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Year Citation  Score
2019 Batki J, Schnabl J, Wang J, Handler D, Andreev VI, Stieger CE, Novatchkova M, Lampersberger L, Kauneckaite K, Xie W, Mechtler K, Patel DJ, Brennecke J. The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. Nature Structural & Molecular Biology. 26: 720-731. PMID 31384064 DOI: 10.1038/s41594-019-0270-6  0.32
2019 Xie W, Lama L, Adura C, Tomita D, Glickman JF, Tuschl T, Patel DJ. Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31142647 DOI: 10.1073/pnas.1905013116  0.36
2019 Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, ... ... Patel DJ, et al. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nature Communications. 10: 2261. PMID 31113940 DOI: 10.1038/s41467-019-08620-4  0.96
2019 Zheng L, Falschlunger C, Huang K, Mairhofer E, Yuan S, Wang J, Patel DJ, Micura R, Ren A. Hatchet ribozyme structure and implications for cleavage mechanism. Proceedings of the National Academy of Sciences of the United States of America. PMID 31088965 DOI: 10.1073/pnas.1902413116  1
2019 Hirano Y, Gao YG, Stephenson DJ, Vu NT, Malinina L, Simanshu DK, Chalfant CE, Patel DJ, Brown RE. Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase Aα. Elife. 8. PMID 31050338 DOI: 10.7554/eLife.44760  0.44
2019 Boekhout M, Karasu ME, Wang J, Acquaviva L, Pratto F, Brick K, Eng DY, Xu J, Camerini-Otero RD, Patel DJ, Keeney S. REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks. Molecular Cell. PMID 31003867 DOI: 10.1016/j.molcel.2019.03.023  0.32
2019 Yang H, Patel DJ. CasX: a new and small CRISPR gene-editing protein. Cell Research. PMID 30992542 DOI: 10.1038/s41422-019-0165-4  0.48
2018 Deng P, Zhou Y, Jiang J, Li H, Tian W, Cao Y, Qin Y, Kim J, Roeder RG, Patel DJ, Wang Z. Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224485 DOI: 10.1073/pnas.1812256115  0.36
2018 Liu Y, Esyunina D, Olovnikov I, Teplova M, Kulbachinskiy A, Aravin AA, Patel DJ. Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Reports. 24: 453-462. PMID 29996105 DOI: 10.1016/j.celrep.2018.06.021  0.48
2018 Noh KM, Wang H, Kim HR, Wenderski W, Fang F, Li CH, Dewell S, Hughes SH, Melnick AM, Patel DJ, Li H, Allis CD. Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs. Molecular Cell. 69: 533. PMID 29395070 DOI: 10.1016/j.molcel.2018.01.014  0.32
2018 Kenoth R, Zou X, Simanshu DK, Pike HM, Malinina L, Patel DJ, Brown RE, Kamlekar RK. Functional evaluation of Tryptophans in glycolipid binding and membrane interaction by HETC2, a fungal glycolipid transfer protein. Biochimica Et Biophysica Acta. PMID 29305831 DOI: 10.1016/j.bbamem.2018.01.001  0.44
2017 Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, ... Patel DJ, et al. Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nature Communications. 8: 1827. PMID 29170402 DOI: 10.1038/s41467-017-01770-3  0.96
2017 Ren A, Micura R, Patel DJ. Structure-based mechanistic insights into catalysis by small self-cleaving ribozymes. Current Opinion in Chemical Biology. 41: 71-83. PMID 29107885 DOI: 10.1016/j.cbpa.2017.09.017  1
2017 Neuner S, Falschlunger C, Fuchs E, Himmelstoss M, Ren A, Patel D, Micura R. Atom-specific mutagenesis reveals structural and catalytic roles for active site-adenosine and hydrated Mg2+ in pistol ribozyme. Angewandte Chemie (International Ed. in English). PMID 29098759 DOI: 10.1002/anie.201708679  1
2017 Hoelper D, Huang H, Jain AY, Patel DJ, Lewis PW. Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX. Nature Communications. 8: 1193. PMID 29084956 DOI: 10.1038/s41467-017-01206-y  0.56
2017 Zheng L, Mairhofer E, Teplova M, Zhang Y, Ma J, Patel DJ, Micura R, Ren A. Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme. Nature Communications. 8: 1180. PMID 29081514 DOI: 10.1038/s41467-017-01276-y  1
2017 Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P, Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ, Subramaniam S. Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell. 171: 414-426.e12. PMID 28985564 DOI: 10.1016/j.cell.2017.09.006  0.48
2017 Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, ... Patel DJ, et al. Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nature Communications. 8: 750. PMID 28963528 DOI: 10.1038/s41467-017-00833-9  0.96
2017 Sheng G, Gogakos T, Wang J, Zhao H, Serganov A, Juranek S, Tuschl T, Patel DJ, Wang Y. Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Research. 45: 9149-9163. PMID 28911094 DOI: 10.1093/nar/gkx547  0.6
2017 Li H, Liefke R, Jiang J, Kurland JV, Tian W, Deng P, Zhang W, He Q, Patel DJ, Bulyk ML, Shi Y, Wang Z. Polycomb-like proteins link the PRC2 complex to CpG islands. Nature. PMID 28869966 DOI: 10.1038/nature23881  0.36
2017 Yang H, Patel DJ. Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9. Molecular Cell. PMID 28602637 DOI: 10.1016/j.molcel.2017.05.024  0.48
2017 Yang H, Patel DJ. New CRISPR-Cas systems discovered. Cell Research. PMID 28220773 DOI: 10.1038/cr.2017.21  0.48
2017 Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki J, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Feng D, ... ... Patel DJ, et al. RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. Rna (New York, N.Y.). PMID 28138060 DOI: 10.1261/rna.060368.116  1
2017 Hammond CM, Strømme CB, Huang H, Patel DJ, Groth A. Histone chaperone networks shaping chromatin function. Nature Reviews. Molecular Cell Biology. PMID 28053344 DOI: 10.1038/nrm.2016.159  0.56
2016 Zhai X, Gao YG, Mishra SK, Simanshu DK, Boldyrev IA, Benson LM, Bergen HR, Malinina L, Mundy J, Molotkovsky JG, Patel DJ, Brown RE. Phosphatidylserine stimulates ceramide-1-phosphate (C1P) intermembrane transfer by C1P transfer proteins. The Journal of Biological Chemistry. PMID 28011644 DOI: 10.1074/jbc.M116.760256  0.44
2016 Yang H, Gao P, Rajashankar KR, Patel DJ. PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell. 167: 1814-1828.e12. PMID 27984729 DOI: 10.1016/j.cell.2016.11.053  0.96
2016 Huang H, Deng Z, Vladimirova O, Wiedmer A, Lu F, Lieberman PM, Patel DJ. Structural basis underlying viral hijacking of a histone chaperone complex. Nature Communications. 7: 12707. PMID 27581705 DOI: 10.1038/ncomms12707  1
2016 Gao P, Yang H, Rajashankar KR, Huang Z, Patel DJ. Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition. Cell Research. PMID 27444870 DOI: 10.1038/cr.2016.88  0.4
2016 Höfer K, Li S, Abele F, Frindert J, Schlotthauer J, Grawenhoff J, Du J, Patel DJ, Jäschke A. Structure and function of the bacterial decapping enzyme NudC. Nature Chemical Biology. PMID 27428510 DOI: 10.1038/nchembio.2132  1
2016 Ren A, Vušurović N, Gebetsberger J, Gao P, Juen M, Kreutz C, Micura R, Patel DJ. Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage. Nature Chemical Biology. PMID 27398999 DOI: 10.1038/nchembio.2125  1
2016 Saredi G, Huang H, Hammond CM, Alabert C, Bekker-Jensen S, Forne I, Reverón-Gómez N, Foster BM, Mlejnkova L, Bartke T, Cejka P, Mailand N, Imhof A, Patel DJ, Groth A. H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex. Nature. PMID 27338793 DOI: 10.1038/nature18312  0.56
2016 Prendergast L, Müller S, Liu Y, Huang H, Dingli F, Loew D, Vassias I, Patel DJ, Sullivan KF, Almouzni G. The CENP-T/-W complex is a binding partner of the histone chaperone FACT. Genes & Development. PMID 27284163 DOI: 10.1101/gad.275073.115  0.56
2015 Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM, Patel DJ. Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Reports. 13: 1800-1813. PMID 26655897 DOI: 10.1016/j.celrep.2015.10.062  1
2015 Murn J, Teplova M, Zarnack K, Shi Y, Patel DJ. Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt. Nature Structural & Molecular Biology. PMID 26641712 DOI: 10.1038/nsmb.3140  0.96
2015 Košutić M, Neuner S, Ren A, Flür S, Wunderlich C, Mairhofer E, Vušurović N, Seikowski J, Breuker K, Höbartner C, Patel DJ, Kreutz C, Micura R. A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class. Angewandte Chemie (International Ed. in English). PMID 26473980 DOI: 10.1002/anie.201506601  1
2015 Chen S, Yang Z, Wilkinson AW, Deshpande AJ, Sidoli S, Krajewski K, Strahl BD, Garcia BA, Armstrong SA, Patel DJ, Gozani O. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Molecular Cell. PMID 26439302 DOI: 10.1016/j.molcel.2015.08.019  1
2015 Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A. Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP. Proceedings of the National Academy of Sciences of the United States of America. 112: E5391-400. PMID 26374839 DOI: 10.1073/pnas.1515737112  1
2015 Teplova M, Farazi TA, Tuschl T, Patel DJ. Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS. Quarterly Reviews of Biophysics. 1-11. PMID 26347403 DOI: 10.1017/S0033583515000207  1
2015 Webster A, Li S, Hur JK, Wachsmuth M, Bois JS, Perkins EM, Patel DJ, Aravin AA. Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper. Molecular Cell. 59: 564-75. PMID 26295961 DOI: 10.1016/j.molcel.2015.07.017  1
2015 Huang H, Strømme CB, Saredi G, Hödl M, Strandsby A, González-Aguilera C, Chen S, Groth A, Patel DJ. A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks. Nature Structural & Molecular Biology. 22: 618-26. PMID 26167883 DOI: 10.1038/nsmb.3055  1
2015 Ren A, Rajashankar KR, Patel DJ. Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism. Structure (London, England : 1993). PMID 26118534 DOI: 10.1016/j.str.2015.05.016  1
2015 Chen S, Rufiange A, Huang H, Rajashankar KR, Nourani A, Patel DJ. Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2. Genes & Development. 29: 1326-40. PMID 26109053 DOI: 10.1101/gad.261115.115  1
2015 Noh KM, Wang H, Kim HR, Wenderski W, Fang F, Li CH, Dewell S, Hughes SH, Melnick AM, Patel DJ, Li H, Allis CD. Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs. Molecular Cell. 59: 89-103. PMID 26073541 DOI: 10.1016/j.molcel.2015.05.017  1
2015 Kim B, Ha M, Loeff L, Chang H, Simanshu DK, Li S, Fareh M, Patel DJ, Joo C, Kim VN. TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms. The Embo Journal. 34: 1801-15. PMID 25979828 DOI: 10.15252/embj.201590931  0.96
2015 Gao P, Patel DJ. V-cGAPs: attenuators of 3'3'-cGAMP signaling. Cell Research. 25: 529-30. PMID 25906992 DOI: 10.1038/cr.2015.48  0.96
2015 Ren A, Wang XC, Kellenberger CA, Rajashankar KR, Jones RA, Hammond MC, Patel DJ. Structural basis for molecular discrimination by a 3',3'-cGAMP sensing riboswitch. Cell Reports. 11: 1-12. PMID 25818298 DOI: 10.1016/j.celrep.2015.03.004  0.96
2015 Malinina L, Simanshu DK, Zhai X, Samygina VR, Kamlekar R, Kenoth R, Ochoa-Lizarralde B, Malakhova ML, Molotkovsky JG, Patel DJ, Brown RE. Sphingolipid transfer proteins defined by the GLTP-fold. Quarterly Reviews of Biophysics. 1-42. PMID 25797198 DOI: 10.1017/S003358351400016X  1
2015 Murn J, Zarnack K, Yang YJ, Durak O, Murphy EA, Cheloufi S, Gonzalez DM, Teplova M, Curk T, Zuber J, Patel DJ, Ule J, Luscombe NM, Tsai LH, Walsh CA, et al. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes & Development. 29: 501-12. PMID 25737280 DOI: 10.1101/gad.258483.115  0.96
2015 Dai Q, Ren A, Westholm JO, Duan H, Patel DJ, Lai EC. Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family. Genes & Development. 29: 48-62. PMID 25561495 DOI: 10.1101/gad.252122.114  0.96
2015 Li H, Zhao S, Patel DJ. Histone recognition by tandem modules and modulation by multiple PTMs Histone Recognition. 149-172. DOI: 10.1007/978-3-319-18102-8_7  1
2014 Lim J, Ha M, Chang H, Kwon SC, Simanshu DK, Patel DJ, Kim VN. Uridylation by TUT4 and TUT7 marks mRNA for degradation. Cell. 159: 1365-76. PMID 25480299 DOI: 10.1016/j.cell.2014.10.055  0.96
2014 Lee M, Choi Y, Kim K, Jin H, Lim J, Nguyen TA, Yang J, Jeong M, Giraldez AJ, Yang H, Patel DJ, Kim VN. Adenylation of maternally inherited microRNAs by Wispy. Molecular Cell. 56: 696-707. PMID 25454948 DOI: 10.1016/j.molcel.2014.10.011  0.96
2014 Ren A, Košuti? M, Rajashankar KR, Frener M, Santner T, Westhof E, Micura R, Patel DJ. In-line alignment and Mg²⁺ coordination at the cleavage site of the env22 twister ribozyme. Nature Communications. 5: 5534. PMID 25410397 DOI: 10.1038/ncomms6534  1
2014 Patel DJ. RNA. Complete pairing not needed. Science (New York, N.Y.). 346: 542-3. PMID 25359948 DOI: 10.1126/science.1262123  1
2014 Kruidenier L, Chung CW, Cheng Z, Liddle J, Che K, Joberty G, Bantscheff M, Bountra C, Bridges A, Diallo H, Eberhard D, Hutchinson S, Jones E, Katso R, Leveridge M, ... ... Patel DJ, et al. Kruidenier et al. reply. Nature. 514: E2. PMID 25279927 DOI: 10.1038/nature13689  0.96
2014 Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ. Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA. Cell Reports. 8: 1668-76. PMID 25199835 DOI: 10.1016/j.celrep.2014.08.010  0.96
2014 Swarts DC, Makarova K, Wang Y, Nakanishi K, Ketting RF, Koonin EV, Patel DJ, van der Oost J. The evolutionary journey of Argonaute proteins. Nature Structural & Molecular Biology. 21: 743-53. PMID 25192263 DOI: 10.1038/nsmb.2879  1
2014 Cheng Z, Cheung P, Kuo AJ, Yukl ET, Wilmot CM, Gozani O, Patel DJ. A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36. Genes & Development. 28: 1758-71. PMID 25128496 DOI: 10.1101/gad.246561.114  1
2014 Ren A, Patel DJ. c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets. Nature Chemical Biology. 10: 780-6. PMID 25086509 DOI: 10.1038/nchembio.1606  1
2014 Du J, Patel DJ. Structural biology-based insights into combinatorial readout and crosstalk among epigenetic marks. Biochimica Et Biophysica Acta. 1839: 719-27. PMID 24747177 DOI: 10.1016/j.bbagrm.2014.04.011  0.96
2014 Swarts DC, Jore MM, Westra ER, Zhu Y, Janssen JH, Snijders AP, Wang Y, Patel DJ, Berenguer J, Brouns SJ, van der Oost J. DNA-guided DNA interference by a prokaryotic Argonaute. Nature. 507: 258-61. PMID 24531762 DOI: 10.1038/nature12971  0.96
2014 Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN, Patel DJ. A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer. Molecular Cell. 53: 606-16. PMID 24486018 DOI: 10.1016/j.molcel.2014.01.003  0.96
2014 Simanshu DK, Zhai X, Munch D, Hofius D, Markham JE, Bielawski J, Bielawska A, Malinina L, Molotkovsky JG, Mundy JW, Patel DJ, Brown RE. Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels. Cell Reports. 6: 388-99. PMID 24412362 DOI: 10.1016/j.celrep.2013.12.023  0.96
2014 Sheng G, Zhao H, Wang J, Rao Y, Tian W, Swarts DC, van der Oost J, Patel DJ, Wang Y. Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proceedings of the National Academy of Sciences of the United States of America. 111: 652-7. PMID 24374628 DOI: 10.1073/pnas.1321032111  0.96
2013 Simanshu DK, Yamaguchi Y, Park JH, Inouye M, Patel DJ. Structural basis of mRNA recognition and cleavage by toxin MazF and its regulation by antitoxin MazE in Bacillus subtilis. Molecular Cell. 52: 447-58. PMID 24120662 DOI: 10.1016/j.molcel.2013.09.006  1
2013 Wang Z, Patel DJ. Small molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases. Quarterly Reviews of Biophysics. 46: 349-73. PMID 23991894 DOI: 10.1017/S0033583513000085  1
2013 Gao P, Ascano M, Zillinger T, Wang W, Dai P, Serganov AA, Gaffney BL, Shuman S, Jones RA, Deng L, Hartmann G, Barchet W, Tuschl T, Patel DJ. Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA. Cell. 154: 748-62. PMID 23910378 DOI: 10.1016/j.cell.2013.07.023  1
2013 Simanshu DK, Kamlekar RK, Wijesinghe DS, Zou X, Zhai X, Mishra SK, Molotkovsky JG, Malinina L, Hinchcliffe EH, Chalfant CE, Brown RE, Patel DJ. Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature. 500: 463-7. PMID 23863933 DOI: 10.1038/nature12332  1
2013 Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature. 500: 93-7. PMID 23812588 DOI: 10.1038/nature12287  1
2013 Nakanishi K, Ascano M, Gogakos T, Ishibe-Murakami S, Serganov AA, Briskin D, Morozov P, Tuschl T, Patel DJ. Eukaryote-specific insertion elements control human ARGONAUTE slicer activity. Cell Reports. 3: 1893-900. PMID 23809764 DOI: 10.1016/j.celrep.2013.06.010  1
2013 Gao P, Ascano M, Wu Y, Barchet W, Gaffney BL, Zillinger T, Serganov AA, Liu Y, Jones RA, Hartmann G, Tuschl T, Patel DJ. Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell. 153: 1094-107. PMID 23647843 DOI: 10.1016/j.cell.2013.04.046  1
2013 Patel DJ, Wang Z. Readout of epigenetic modifications. Annual Review of Biochemistry. 82: 81-118. PMID 23642229 DOI: 10.1146/annurev-biochem-072711-165700  1
2013 Shen J, Xia W, Khotskaya YB, Huo L, Nakanishi K, Lim SO, Du Y, Wang Y, Chang WC, Chen CH, Hsu JL, Wu Y, Lam YC, James BP, Liu X, ... ... Patel DJ, et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature. 497: 383-7. PMID 23636329 DOI: 10.1038/nature12080  1
2013 Teplova M, Hafner M, Teplov D, Essig K, Tuschl T, Patel DJ. Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites. Genes & Development. 27: 928-40. PMID 23630077 DOI: 10.1101/gad.216531.113  1
2013 Samygina VR, Ochoa-Lizarralde B, Popov AN, Cabo-Bilbao A, Goni-de-Cerio F, Molotkovsky JG, Patel DJ, Brown RE, Malinina L. Structural insights into lipid-dependent reversible dimerization of human GLTP. Acta Crystallographica. Section D, Biological Crystallography. 69: 603-16. PMID 23519669 DOI: 10.1107/S0907444913000024  1
2013 Dai Q, Ren A, Westholm JO, Serganov AA, Patel DJ, Lai EC. The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors. Genes & Development. 27: 602-14. PMID 23468431 DOI: 10.1101/gad.213314.113  1
2013 Oh YS, Gao P, Lee KW, Ceglia I, Seo JS, Zhang X, Ahn JH, Chait BT, Patel DJ, Kim Y, Greengard P. SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action. Cell. 152: 831-43. PMID 23415230 DOI: 10.1016/j.cell.2013.01.014  1
2013 Khutsishvili I, Zhang N, Marky LA, Crean C, Patel DJ, Geacintov NE, Shafirovich V. Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions. Biochemistry. 52: 1354-63. PMID 23360616 DOI: 10.1021/bi301566v  1
2013 Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG. An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Molecular Cell. 49: 571-82. PMID 23273982 DOI: 10.1016/j.molcel.2012.11.026  1
2013 Kamlekar RK, Simanshu DK, Gao YG, Kenoth R, Pike HM, Prendergast FG, Malinina L, Molotkovsky JG, Venyaminov SY, Patel DJ, Brown RE. The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids. Biochimica Et Biophysica Acta. 1831: 417-27. PMID 23159414 DOI: 10.1016/j.bbalip.2012.10.010  1
2012 Kuryavyi V, Cahoon LA, Seifert HS, Patel DJ. RecA-binding pilE G4 sequence essential for pilin antigenic variation forms monomeric and 5' end-stacked dimeric parallel G-quadruplexes. Structure (London, England : 1993). 20: 2090-102. PMID 23085077 DOI: 10.1016/j.str.2012.09.013  1
2012 Elsässer SJ, Huang H, Lewis PW, Chin JW, Allis CD, Patel DJ. DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition. Nature. 491: 560-5. PMID 23075851 DOI: 10.1038/nature11608  1
2012 Kruidenier L, Chung CW, Cheng Z, Liddle J, Che K, Joberty G, Bantscheff M, Bountra C, Bridges A, Diallo H, Eberhard D, Hutchinson S, Jones E, Katso R, Leveridge M, ... ... Patel DJ, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 488: 404-8. PMID 22842901 DOI: 10.1038/nature11262  1
2012 Nakanishi K, Weinberg DE, Bartel DP, Patel DJ. Structure of yeast Argonaute with guide RNA. Nature. 486: 368-74. PMID 22722195 DOI: 10.1038/nature11211  1
2012 Ren A, Rajashankar KR, Patel DJ. Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch. Nature. 486: 85-9. PMID 22678284 DOI: 10.1038/nature11152  1
2012 Ausin I, Greenberg MV, Simanshu DK, Hale CJ, Vashisht AA, Simon SA, Lee TF, Feng S, Española SD, Meyers BC, Wohlschlegel JA, Patel DJ, Jacobsen SE. INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America. 109: 8374-81. PMID 22592791 DOI: 10.1073/pnas.1206638109  0.44
2012 Serganov A, Patel DJ. Molecular recognition and function of riboswitches. Current Opinion in Structural Biology. 22: 279-86. PMID 22579413 DOI: 10.1016/j.sbi.2012.04.005  1
2012 Serganov A, Patel DJ. Metabolite recognition principles and molecular mechanisms underlying riboswitch function. Annual Review of Biophysics. 41: 343-70. PMID 22577823 DOI: 10.1146/annurev-biophys-101211-113224  1
2012 Kuo AJ, Song J, Cheung P, Ishibe-Murakami S, Yamazoe S, Chen JK, Patel DJ, Gozani O. The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome. Nature. 484: 115-9. PMID 22398447 DOI: 10.1038/nature10956  1
2012 Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, ... Patel DJ, et al. RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction. Rna (New York, N.Y.). 18: 610-25. PMID 22361291 DOI: 10.1261/rna.031054.111  1
2012 Song J, Teplova M, Ishibe-Murakami S, Patel DJ. Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation. Science (New York, N.Y.). 335: 709-12. PMID 22323818 DOI: 10.1126/science.1214453  1
2012 Du J, Kelly AE, Funabiki H, Patel DJ. Structural basis for recognition of H3T3ph and Smac/DIABLO N-terminal peptides by human Survivin. Structure (London, England : 1993). 20: 185-95. PMID 22244766 DOI: 10.1016/j.str.2011.12.001  1
2011 Xi Q, Wang Z, Zaromytidou AI, Zhang XH, Chow-Tsang LF, Liu JX, Kim H, Barlas A, Manova-Todorova K, Kaartinen V, Studer L, Mark W, Patel DJ, Massagué J. A poised chromatin platform for TGF-β access to master regulators. Cell. 147: 1511-24. PMID 22196728 DOI: 10.1016/j.cell.2011.11.032  1
2011 Samygina VR, Popov AN, Cabo-Bilbao A, Ochoa-Lizarralde B, Goni-de-Cerio F, Zhai X, Molotkovsky JG, Patel DJ, Brown RE, Malinina L. Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein. Structure (London, England : 1993). 19: 1644-54. PMID 22078563 DOI: 10.1016/j.str.2011.09.011  1
2011 Huang L, Ishibe-Murakami S, Patel DJ, Serganov A. Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch. Proceedings of the National Academy of Sciences of the United States of America. 108: 14801-6. PMID 21873197 DOI: 10.1073/pnas.1111701108  1
2011 Pikovskaya O, Polonskaia A, Patel DJ, Serganov A. Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch. Nature Chemical Biology. 7: 748-55. PMID 21841796 DOI: 10.1038/nchembio.631  1
2011 Teplova M, Wohlbold L, Khin NW, Izaurralde E, Patel DJ. Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nature Structural & Molecular Biology. 18: 990-8. PMID 21822283 DOI: 10.1038/nsmb.2094  1
2011 Weinberg DE, Nakanishi K, Patel DJ, Bartel DP. The inside-out mechanism of Dicers from budding yeasts. Cell. 146: 262-76. PMID 21784247 DOI: 10.1016/j.cell.2011.06.021  1
2011 Rajakumara E, Wang Z, Ma H, Hu L, Chen H, Lin Y, Guo R, Wu F, Li H, Lan F, Shi YG, Xu Y, Patel DJ, Shi Y. PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression. Molecular Cell. 43: 275-84. PMID 21777816 DOI: 10.1016/j.molcel.2011.07.006  1
2011 Reeves DA, Mu H, Kropachev K, Cai Y, Ding S, Kolbanovskiy A, Kolbanovskiy M, Chen Y, Krzeminski J, Amin S, Patel DJ, Broyde S, Geacintov NE. Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions. Nucleic Acids Research. 39: 8752-64. PMID 21764772 DOI: 10.1093/nar/gkr537  1
2011 Park JE, Heo I, Tian Y, Simanshu DK, Chang H, Jee D, Patel DJ, Kim VN. Dicer recognizes the 5' end of RNA for efficient and accurate processing. Nature. 475: 201-5. PMID 21753850 DOI: 10.1038/nature10198  1
2011 Teplova M, Malinina L, Darnell JC, Song J, Lu M, Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB, Patel DJ. Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. Structure (London, England : 1993). 19: 930-44. PMID 21742260 DOI: 10.1016/j.str.2011.05.002  1
2011 Iwase S, Xiang B, Ghosh S, Ren T, Lewis PW, Cochrane JC, Allis CD, Picketts DJ, Patel DJ, Li H, Shi Y. ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nature Structural & Molecular Biology. 18: 769-76. PMID 21666679 DOI: 10.1038/nsmb.2062  1
2011 Rechkoblit O, Delaney JC, Essigmann JM, Patel DJ. Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure (London, England : 1993). 19: 821-32. PMID 21645853 DOI: 10.1016/j.str.2011.03.020  1
2011 Phan AT, Kuryavyi V, Darnell JC, Serganov A, Majumdar A, Ilin S, Raslin T, Polonskaia A, Chen C, Clain D, Darnell RB, Patel DJ. Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. Nature Structural & Molecular Biology. 18: 796-804. PMID 21642970 DOI: 10.1038/nsmb.2064  1
2011 Ruthenburg AJ, Li H, Milne TA, Dewell S, McGinty RK, Yuen M, Ueberheide B, Dou Y, Muir TW, Patel DJ, Allis CD. Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell. 145: 692-706. PMID 21596426 DOI: 10.1016/j.cell.2011.03.053  1
2011 Kenoth R, Kamlekar RK, Simanshu DK, Gao Y, Malinina L, Prendergast FG, Molotkovsky JG, Patel DJ, Venyaminov SY, Brown RE. Conformational folding and stability of the HET-C2 glycolipid transfer protein fold: does a molten globule-like state regulate activity? Biochemistry. 50: 5163-71. PMID 21553912 DOI: 10.1021/bi200382c  1
2011 Tian Y, Simanshu DK, Ascano M, Diaz-Avalos R, Park AY, Juranek SA, Rice WJ, Yin Q, Robinson CV, Tuschl T, Patel DJ. Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex. Nature Structural & Molecular Biology. 18: 658-64. PMID 21552261 DOI: 10.1038/nsmb.2069  1
2011 Wang Z, Patel DJ. Combinatorial readout of dual histone modifications by paired chromatin-associated modules. The Journal of Biological Chemistry. 286: 18363-8. PMID 21454653 DOI: 10.1074/jbc.R111.219139  1
2011 Rajakumara E, Law JA, Simanshu DK, Voigt P, Johnson LM, Reinberg D, Patel DJ, Jacobsen SE. A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes & Development. 25: 137-52. PMID 21245167 DOI: 10.1101/gad.1980311  0.44
2011 Tian Y, Simanshu DK, Ma JB, Patel DJ. Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proceedings of the National Academy of Sciences of the United States of America. 108: 903-10. PMID 21193640 DOI: 10.1073/pnas.1017762108  1
2011 Song J, Rechkoblit O, Bestor TH, Patel DJ. Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science (New York, N.Y.). 331: 1036-40. PMID 21163962 DOI: 10.1126/science.1195380  1
2011 Rüdel S, Wang Y, Lenobel R, Körner R, Hsiao HH, Urlaub H, Patel D, Meister G. Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Research. 39: 2330-43. PMID 21071408 DOI: 10.1093/nar/gkq1032  1
2011 Mallikaratchy PR, Ruggiero A, Gardner JR, Kuryavyi V, Maguire WF, Heaney ML, McDevitt MR, Patel DJ, Scheinberg DA. A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia. Nucleic Acids Research. 39: 2458-69. PMID 21030439 DOI: 10.1093/nar/gkq996  1
2011 Broyde S, Wang L, Cai Y, Jia L, Shapiro R, Patel DJ, Geacintov NE. Covalent polycyclic aromatic hydrocarbon-DNA adducts: Carcinogenicity, structure, and function Current Cancer Research. 6: 181-207. DOI: 10.1007/978-1-61737-995-6_9  1
2010 Tsai WW, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S, Tsai CY, Shi X, Schwarzer D, Plunkett W, Aronow B, Gozani O, Fischle W, Hung MC, Patel DJ, et al. TRIM24 links a non-canonical histone signature to breast cancer. Nature. 468: 927-32. PMID 21164480 DOI: 10.1038/nature09542  1
2010 Huang L, Serganov A, Patel DJ. Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Molecular Cell. 40: 774-86. PMID 21145485 DOI: 10.1016/j.molcel.2010.11.026  1
2010 Kamlekar RK, Gao Y, Kenoth R, Molotkovsky JG, Prendergast FG, Malinina L, Patel DJ, Wessels WS, Venyaminov SY, Brown RE. Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold. Biophysical Journal. 99: 2626-35. PMID 20959104 DOI: 10.1016/j.bpj.2010.08.038  1
2010 Teplova M, Song J, Gaw HY, Teplov A, Patel DJ. Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1. Structure (London, England : 1993). 18: 1364-77. PMID 20947024 DOI: 10.1016/j.str.2010.06.018  1
2010 Cai Y, Patel DJ, Broyde S, Geacintov NE. Base sequence context effects on nucleotide excision repair. Journal of Nucleic Acids. 2010. PMID 20871811 DOI: 10.4061/2010/174252  1
2010 Wang Y, Ludwig J, Schuberth C, Goldeck M, Schlee M, Li H, Juranek S, Sheng G, Micura R, Tuschl T, Hartmann G, Patel DJ. Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I. Nature Structural & Molecular Biology. 17: 781-7. PMID 20581823 DOI: 10.1038/nsmb.1863  1
2010 Broyde S, Patel DJ. DNA repair: How to accurately bypass damage. Nature. 465: 1023-4. PMID 20577203 DOI: 10.1038/4651023a  1
2010 Kuryavyi V, Phan AT, Patel DJ. Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter. Nucleic Acids Research. 38: 6757-73. PMID 20566478 DOI: 10.1093/nar/gkq558  1
2010 Wang Z, Song J, Milne TA, Wang GG, Li H, Allis CD, Patel DJ. Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell. 141: 1183-94. PMID 20541251 DOI: 10.1016/j.cell.2010.05.016  1
2010 Cai Y, Kropachev K, Xu R, Tang Y, Kolbanovskii M, Kolbanovskii A, Amin S, Patel DJ, Broyde S, Geacintov NE. Distant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion. Journal of Molecular Biology. 399: 397-409. PMID 20399214 DOI: 10.1016/j.jmb.2010.04.004  1
2010 Kenoth R, Simanshu DK, Kamlekar RK, Pike HM, Molotkovsky JG, Benson LM, Bergen HR, Prendergast FG, Malinina L, Venyaminov SY, Patel DJ, Brown RE. Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. The Journal of Biological Chemistry. 285: 13066-78. PMID 20164530 DOI: 10.1074/jbc.M109.093203  1
2010 Rechkoblit O, Kolbanovskiy A, Malinina L, Geacintov NE, Broyde S, Patel DJ. Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nature Structural & Molecular Biology. 17: 379-88. PMID 20154704 DOI: 10.1038/nsmb.1771  1
2010 Kuryavyi V, Patel DJ. Solution structure of a unique G-quadruplex scaffold adopted by a guanosine-rich human intronic sequence. Structure (London, England : 1993). 18: 73-82. PMID 20152154 DOI: 10.1016/j.str.2009.10.015  1
2010 Telvekar VN, Patel DJ, Jadhav NC, Mishra SJ. Three-dimensional QSAR and pharmacophore mapping of biphenyl benzoic acid derivatives as selective human β3-adrenergic receptor agonists Medicinal Chemistry Research. 19: 1174-1190. DOI: 10.1007/s00044-009-9261-1  0.56
2010 Broyde S, Wang L, Patel DJ, Geacintov NE. Elucidating Structure-Function Relationships in Bulky DNA Lesions: From Solution Structures to Polymerases The Chemical Biology of Dna Damage. 331-352. DOI: 10.1002/9783527630110.ch14  1
2010 Cai Y, Kropachev K, Kolbanovskiy M, Kolbanovskiy A, Broyde S, Patel DJ, Geacintov NE. Recognition and Removal of Bulky DNA Lesions by the Nucleotide Excision Repair System The Chemical Biology of Dna Damage. 261-298. DOI: 10.1002/9783527630110.ch12  1
2009 Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ. Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature. 461: 754-61. PMID 19812667 DOI: 10.1038/nature08434  1
2009 Serganov A, Patel DJ. Amino acid recognition and gene regulation by riboswitches. Biochimica Et Biophysica Acta. 1789: 592-611. PMID 19619684 DOI: 10.1016/j.bbagrm.2009.07.002  1
2009 Zhang N, Ding S, Kolbanovskiy A, Shastry A, Kuzmin VA, Bolton JL, Patel DJ, Broyde S, Geacintov NE. NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms. Biochemistry. 48: 7098-109. PMID 19527068 DOI: 10.1021/bi9006429  1
2009 Westhof E, Patel DJ. Nucleic acids: how high resolution structural biology help us to understand Darwinian evolution. Current Opinion in Structural Biology. 19: 235-8. PMID 19482468 DOI: 10.1016/j.sbi.2009.04.004  1
2009 Rechkoblit O, Malinina L, Cheng Y, Geacintov NE, Broyde S, Patel DJ. Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure (London, England : 1993). 17: 725-36. PMID 19446528 DOI: 10.1016/j.str.2009.03.011  1
2009 Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature. 459: 847-51. PMID 19430464 DOI: 10.1038/nature08036  1
2009 Li H, Motamedi MR, Yip CK, Wang Z, Walz T, Patel DJ, Moazed D. An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Molecular Cell. 34: 155-67. PMID 19394293 DOI: 10.1016/j.molcel.2009.02.032  1
2009 Pikovskaya O, Serganov AA, Polonskaia A, Serganov A, Patel DJ. Preparation and crystallization of riboswitch-ligand complexes Methods in Molecular Biology (Clifton, N.J.). 540: 115-128. PMID 19381556 DOI: 10.1007/978-1-59745-558-9_9  1
2009 Lim KW, Amrane S, Bouaziz S, Xu W, Mu Y, Patel DJ, Luu KN, Phan AT. Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers. Journal of the American Chemical Society. 131: 4301-9. PMID 19271707 DOI: 10.1021/ja807503g  1
2009 Zhai X, Malakhova ML, Pike HM, Benson LM, Bergen HR, Sugár IP, Malinina L, Patel DJ, Brown RE. Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: insights into glycolipid binding affinity. The Journal of Biological Chemistry. 284: 13620-8. PMID 19270338 DOI: 10.1074/jbc.M809089200  1
2009 Zhao Q, Rank G, Tan YT, Li H, Moritz RL, Simpson RJ, Cerruti L, Curtis DJ, Patel DJ, Allis CD, Cunningham JM, Jane SM. PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing. Nature Structural & Molecular Biology. 16: 304-11. PMID 19234465 DOI: 10.1038/nsmb.1568  1
2009 Serganov A, Huang L, Patel DJ. Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch Nature. 458: 233-237. PMID 19169240 DOI: 10.1038/nature07642  1
2009 Kropachev K, Kolbanovskii M, Cai Y, Rodríguez F, Kolbanovskii A, Liu Y, Zhang L, Amin S, Patel D, Broyde S, Geacintov NE. The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions. Journal of Molecular Biology. 386: 1193-203. PMID 19162041 DOI: 10.1016/j.jmb.2008.12.082  1
2007 Bailor MH, Musselman C, Hansen AL, Gulati K, Patel DJ, Al-Hashimi HM. Characterizing the relative orientation and dynamics of RNA A-form helices using NMR residual dipolar couplings. Nature Protocols. 2: 1536-46. PMID 17571061 DOI: 10.1038/nprot.2007.221  1
2005 Pitt SW, Zhang Q, Patel DJ, Al-Hashimi HM. Evidence that electrostatic interactions dictate the ligand-induced arrest of RNA global flexibility. Angewandte Chemie (International Ed. in English). 44: 3412-5. PMID 15861447 DOI: 10.1002/anie.200500075  1
2004 Pitt SW, Majumdar A, Serganov A, Patel DJ, Al-Hashimi HM. Argininamide binding arrests global motions in HIV-1 TAR RNA: comparison with Mg2+-induced conformational stabilization. Journal of Molecular Biology. 338: 7-16. PMID 15050819 DOI: 10.1016/j.jmb.2004.02.031  1
2003 Al-Hashimi HM, Pitt SW, Majumdar A, Xu W, Patel DJ. Mg2+-induced variations in the conformation and dynamics of HIV-1 TAR RNA probed using NMR residual dipolar couplings. Journal of Molecular Biology. 329: 867-73. PMID 12798678 DOI: 10.1016/S0022-2836(03)00517-5  1
2002 Al-Hashimi HM, Gorin A, Majumdar A, Gosser Y, Patel DJ. Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings. Journal of Molecular Biology. 318: 637-49. PMID 12054812 DOI: 10.1016/S0022-2836(02)00160-2  1
2002 Al-Hashimi HM, Patel DJ. Residual dipolar couplings: synergy between NMR and structural genomics. Journal of Biomolecular Nmr. 22: 1-8. PMID 11885976 DOI: 10.1023/A:1013801714041  1
2002 Al-Hashimi HM, Gosser Y, Gorin A, Hu W, Majumdar A, Patel DJ. Concerted motions in HIV-1 TAR RNA may allow access to bound state conformations: RNA dynamics from NMR residual dipolar couplings. Journal of Molecular Biology. 315: 95-102. PMID 11779230 DOI: 10.1006/jmbi.2001.5235  1
2001 Al-Hashimi HM, Gorin A, Majumdar A, Patel DJ. Alignment of the HTLV-I Rex peptide bound to its target RNA aptamer from magnetic field-induced residual dipolar couplings and intermolecular hydrogen bonds. Journal of the American Chemical Society. 123: 3179-80. PMID 11457047 DOI: 10.1021/ja004133w  1
2001 Al-Hashimi HM, Majumdar A, Gorin A, Kettani A, Skripkin E, Patel DJ. Field- and phage-induced dipolar couplings in a homodimeric DNA quadruplex: relative orientation of G.(C-A) triad and G-tetrad motifs and direct determination of C2 symmetry axis orientation. Journal of the American Chemical Society. 123: 633-40. PMID 11456575 DOI: 10.1021/ja003379y  1
2001 Al-Hashimi HM, Tolman JR, Majumdar A, Gorin A, Patel DJ. Determining stoichiometry in homomultimeric nucleic acid complexes using magnetic field induced residual dipolar couplings. Journal of the American Chemical Society. 123: 5806-7. PMID 11403617 DOI: 10.1021/ja0105865  1
1996 Greenbaum NL, Radhakrishnan I, Patel DJ, Hirsh D. Solution structure of the donor site of a trans-splicing RNA. Structure (London, England : 1993). 4: 725-33. PMID 8805553  1
1995 Greenbaum NL, Radhakrishnan I, Hirsh D, Patel DJ. Determination of the folding topology of the SL1 RNA from Caenorhabditis elegans by multidimensional heteronuclear NMR. Journal of Molecular Biology. 252: 314-27. PMID 7563053 DOI: 10.1006/jmbi.1995.0499  1
1992 Gao XL, Mirau P, Patel DJ. Structure refinement of the chromomycin dimer-DNA oligomer complex in solution. Journal of Molecular Biology. 223: 259-79. PMID 1731073  0.92
1992 Radhakrishnan I, Patel DJ, Gao X. Three-dimensional homonuclear NOESY-TOCSY of an intramolecular pyrimidine.purine.pyrimidine DNA triplex containing a central G.TA triple: nonexchangeable proton assignments and structural implications. Biochemistry. 31: 2514-23. PMID 1547235  0.96
1992 Leroy JL, Gao XL, Misra V, Guéron M, Patel DJ. Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening. Biochemistry. 31: 1407-15. PMID 1310611  1
1991 Wang Y, de los Santos C, Gao XO, Greene K, Live D, Patel DJ. Multinuclear nuclear magnetic resonance studies of Na cation-stabilized complex formed by d(G-G-T-T-T-T-C-G-G) in solution. Implications for G-tetrad structures. Journal of Molecular Biology. 222: 819-32. PMID 1660934  0.44
1991 Radhakrishnan I, Gao X, de los Santos C, Live D, Patel DJ. NMR structural studies of intramolecular (Y+)n.(R+)n(Y-)nDNA triplexes in solution: imino and amino proton and nitrogen markers of G.TA base triple formation. Biochemistry. 30: 9022-30. PMID 1654085  0.96
1991 Leroy JL, Gao XL, Guéron M, Patel DJ. Proton exchange and internal motions in two chromomycin dimer-DNA oligomer complexes. Biochemistry. 30: 5653-61. PMID 1645996  1
1990 Gao XL, Patel DJ. Chromomycin dimer-DNA oligomer complexes. Sequence selectivity and divalent cation specificity. Biochemistry. 29: 10940-56. PMID 2176890  0.92
1989 Gao XL, Patel DJ. Solution structure of the chromomycin-DNA complex. Biochemistry. 28: 751-62. PMID 2713341  0.92
1989 Gao XL, Patel DJ. Antitumour drug-DNA interactions: NMR studies of echinomycin and chromomycin complexes. Quarterly Reviews of Biophysics. 22: 93-138. PMID 2675172  0.92
1988 Gao XL, Patel DJ. NMR studies of echinomycin bisintercalation complexes with d(A1-C2-G3-T4) and d(T1-C2-G3-A4) duplexes in aqueous solution: sequence-dependent formation of Hoogsteen A1.T4 and Watson--Crick T1.A4 base pairs flanking the bisintercalation site. Biochemistry. 27: 1744-51. PMID 3365421  0.92
1987 Gao XL, Patel DJ. NMR studies of A.C mismatches in DNA dodecanucleotides at acidic pH. Wobble A(anti).C(anti) pair formation. The Journal of Biological Chemistry. 262: 16973-84. PMID 3680285  0.92
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