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Year Citation  Score
2020 Miao Z, Adamiak RW, Antczak M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Cheng Y, Chou FC, Das R, Dokholyan NV, Ding F, Geniesse C, Jiang Y, Joshi A, ... ... Patel DJ, et al. RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers. Rna (New York, N.Y.). PMID 32371455 DOI: 10.1261/rna.075341.120  1
2020 Hohl M, Mojumdar A, Hailemariam S, Kuryavyi V, Ghisays F, Sorenson K, Chang M, Taylor BS, Patel DJ, Burgers PM, Cobb JA, Petrini JHJ. Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis. Plos Genetics. 16: e1008422. PMID 32187176 DOI: 10.1371/journal.pgen.1008422  0.4
2019 Teplova M, Falschlunger C, Krasheninina O, Egger M, Ren A, Patel DJ, Micura R. On crucial roles of two hydrated Mg2+ ions in reaction catalysis of the pistol ribozyme. Angewandte Chemie (International Ed. in English). PMID 31804735 DOI: 10.1002/anie.201912522  1
2019 Batki J, Schnabl J, Wang J, Handler D, Andreev VI, Stieger CE, Novatchkova M, Lampersberger L, Kauneckaite K, Xie W, Mechtler K, Patel DJ, Brennecke J. The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. Nature Structural & Molecular Biology. 26: 720-731. PMID 31384064 DOI: 10.1038/s41594-019-0270-6  0.32
2019 Xie W, Lama L, Adura C, Tomita D, Glickman JF, Tuschl T, Patel DJ. Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31142647 DOI: 10.1073/pnas.1905013116  0.48
2019 Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, ... ... Patel DJ, et al. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nature Communications. 10: 2261. PMID 31113940 DOI: 10.1038/s41467-019-08620-4  0.96
2019 Zheng L, Falschlunger C, Huang K, Mairhofer E, Yuan S, Wang J, Patel DJ, Micura R, Ren A. Hatchet ribozyme structure and implications for cleavage mechanism. Proceedings of the National Academy of Sciences of the United States of America. PMID 31088965 DOI: 10.1073/pnas.1902413116  1
2019 Hirano Y, Gao YG, Stephenson DJ, Vu NT, Malinina L, Simanshu DK, Chalfant CE, Patel DJ, Brown RE. Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase Aα. Elife. 8. PMID 31050338 DOI: 10.7554/eLife.44760  0.44
2019 Boekhout M, Karasu ME, Wang J, Acquaviva L, Pratto F, Brick K, Eng DY, Xu J, Camerini-Otero RD, Patel DJ, Keeney S. REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks. Molecular Cell. PMID 31003867 DOI: 10.1016/j.molcel.2019.03.023  0.32
2019 Yang H, Patel DJ. CasX: a new and small CRISPR gene-editing protein. Cell Research. PMID 30992542 DOI: 10.1038/s41422-019-0165-4  0.48
2018 Deng P, Zhou Y, Jiang J, Li H, Tian W, Cao Y, Qin Y, Kim J, Roeder RG, Patel DJ, Wang Z. Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224485 DOI: 10.1073/pnas.1812256115  0.4
2018 Liu Y, Esyunina D, Olovnikov I, Teplova M, Kulbachinskiy A, Aravin AA, Patel DJ. Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Reports. 24: 453-462. PMID 29996105 DOI: 10.1016/j.celrep.2018.06.021  0.56
2018 Noh KM, Wang H, Kim HR, Wenderski W, Fang F, Li CH, Dewell S, Hughes SH, Melnick AM, Patel DJ, Li H, Allis CD. Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs. Molecular Cell. 69: 533. PMID 29395070 DOI: 10.1016/j.molcel.2018.01.014  0.4
2018 Kenoth R, Zou X, Simanshu DK, Pike HM, Malinina L, Patel DJ, Brown RE, Kamlekar RK. Functional evaluation of Tryptophans in glycolipid binding and membrane interaction by HETC2, a fungal glycolipid transfer protein. Biochimica Et Biophysica Acta. PMID 29305831 DOI: 10.1016/j.bbamem.2018.01.001  0.44
2018 Eng ET, Yang H, Raczkowski AM, Patel D, Potter CS, Carragher B. Cryo-EM Studies on the Mechanism and Inhibition of Target DNA Binding in the Type I-F Csy Surveillance Complex Biophysical Journal. 114: 164a. DOI: 10.1016/j.bpj.2017.11.918  0.48
2017 Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, ... Patel DJ, et al. Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nature Communications. 8: 1827. PMID 29170402 DOI: 10.1038/s41467-017-01770-3  0.96
2017 Ren A, Micura R, Patel DJ. Structure-based mechanistic insights into catalysis by small self-cleaving ribozymes. Current Opinion in Chemical Biology. 41: 71-83. PMID 29107885 DOI: 10.1016/j.cbpa.2017.09.017  1
2017 Neuner S, Falschlunger C, Fuchs E, Himmelstoss M, Ren A, Patel D, Micura R. Atom-specific mutagenesis reveals structural and catalytic roles for active site-adenosine and hydrated Mg2+ in pistol ribozyme. Angewandte Chemie (International Ed. in English). PMID 29098759 DOI: 10.1002/anie.201708679  1
2017 Hoelper D, Huang H, Jain AY, Patel DJ, Lewis PW. Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX. Nature Communications. 8: 1193. PMID 29084956 DOI: 10.1038/s41467-017-01206-y  0.56
2017 Zheng L, Mairhofer E, Teplova M, Zhang Y, Ma J, Patel DJ, Micura R, Ren A. Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme. Nature Communications. 8: 1180. PMID 29081514 DOI: 10.1038/s41467-017-01276-y  1
2017 Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P, Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ, Subramaniam S. Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell. 171: 414-426.e12. PMID 28985564 DOI: 10.1016/j.cell.2017.09.006  0.48
2017 Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, ... Patel DJ, et al. Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nature Communications. 8: 750. PMID 28963528 DOI: 10.1038/s41467-017-00833-9  0.96
2017 Sheng G, Gogakos T, Wang J, Zhao H, Serganov A, Juranek S, Tuschl T, Patel DJ, Wang Y. Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Research. 45: 9149-9163. PMID 28911094 DOI: 10.1093/nar/gkx547  0.6
2017 Li H, Liefke R, Jiang J, Kurland JV, Tian W, Deng P, Zhang W, He Q, Patel DJ, Bulyk ML, Shi Y, Wang Z. Polycomb-like proteins link the PRC2 complex to CpG islands. Nature. PMID 28869966 DOI: 10.1038/nature23881  0.4
2017 Yang H, Patel DJ. Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9. Molecular Cell. PMID 28602637 DOI: 10.1016/j.molcel.2017.05.024  0.48
2017 Malinina L, Patel DJ, Brown RE. How α-Helical Motifs Form Functionally Diverse Lipid-Binding Compartments. Annual Review of Biochemistry. PMID 28375742 DOI: 10.1146/annurev-biochem-061516-044445  0.4
2017 Yang H, Patel DJ. New CRISPR-Cas systems discovered. Cell Research. PMID 28220773 DOI: 10.1038/cr.2017.21  0.48
2017 Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki J, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Feng D, ... ... Patel DJ, et al. RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. Rna (New York, N.Y.). PMID 28138060 DOI: 10.1261/rna.060368.116  1
2017 Hammond CM, Strømme CB, Huang H, Patel DJ, Groth A. Histone chaperone networks shaping chromatin function. Nature Reviews. Molecular Cell Biology. PMID 28053344 DOI: 10.1038/nrm.2016.159  0.56
2017 Zhai X, Gao Y, Boldyrev IA, Malinina L, Patel DJ, Molotkovsky JG, Chalfant CA, Brown RE. Regulation of Membrane Binding by the C2-Domain of Cytoplasmic Phospholipase A2 by Ceramide-1-Phosphate and Calcium Biophysical Journal. 112: 392a-393a. DOI: 10.1016/j.bpj.2016.11.2132  0.4
2017 Zhai X, Simanshu DK, Boldyrev IA, Pike HM, Mundy J, Malinina L, Molotkovsky JG, Patel DJ, Brown RE. Sphingolipid Transfer by GLTP-fold Proteins is Differentially Regulated by Phosphatidylinositol Derivatives Biophysical Journal. 112: 229a. DOI: 10.1016/j.bpj.2016.11.1259  0.44
2016 Zhai X, Gao YG, Mishra SK, Simanshu DK, Boldyrev IA, Benson LM, Bergen HR, Malinina L, Mundy J, Molotkovsky JG, Patel DJ, Brown RE. Phosphatidylserine stimulates ceramide-1-phosphate (C1P) intermembrane transfer by C1P transfer proteins. The Journal of Biological Chemistry. PMID 28011644 DOI: 10.1074/jbc.M116.760256  0.44
2016 Yang H, Gao P, Rajashankar KR, Patel DJ. PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell. 167: 1814-1828.e12. PMID 27984729 DOI: 10.1016/j.cell.2016.11.053  0.96
2016 Huang H, Deng Z, Vladimirova O, Wiedmer A, Lu F, Lieberman PM, Patel DJ. Structural basis underlying viral hijacking of a histone chaperone complex. Nature Communications. 7: 12707. PMID 27581705 DOI: 10.1038/ncomms12707  1
2016 Gao P, Yang H, Rajashankar KR, Huang Z, Patel DJ. Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition. Cell Research. PMID 27444870 DOI: 10.1038/cr.2016.88  0.4
2016 Höfer K, Li S, Abele F, Frindert J, Schlotthauer J, Grawenhoff J, Du J, Patel DJ, Jäschke A. Structure and function of the bacterial decapping enzyme NudC. Nature Chemical Biology. PMID 27428510 DOI: 10.1038/nchembio.2132  1
2016 Ren A, Vušurović N, Gebetsberger J, Gao P, Juen M, Kreutz C, Micura R, Patel DJ. Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage. Nature Chemical Biology. PMID 27398999 DOI: 10.1038/nchembio.2125  1
2016 Saredi G, Huang H, Hammond CM, Alabert C, Bekker-Jensen S, Forne I, Reverón-Gómez N, Foster BM, Mlejnkova L, Bartke T, Cejka P, Mailand N, Imhof A, Patel DJ, Groth A. H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex. Nature. PMID 27338793 DOI: 10.1038/nature18312  0.56
2016 Prendergast L, Müller S, Liu Y, Huang H, Dingli F, Loew D, Vassias I, Patel DJ, Sullivan KF, Almouzni G. The CENP-T/-W complex is a binding partner of the histone chaperone FACT. Genes & Development. PMID 27284163 DOI: 10.1101/gad.275073.115  0.56
2015 Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM, Patel DJ. Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Reports. 13: 1800-1813. PMID 26655897 DOI: 10.1016/j.celrep.2015.10.062  1
2015 Murn J, Teplova M, Zarnack K, Shi Y, Patel DJ. Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt. Nature Structural & Molecular Biology. PMID 26641712 DOI: 10.1038/nsmb.3140  0.96
2015 Košutić M, Neuner S, Ren A, Flür S, Wunderlich C, Mairhofer E, Vušurović N, Seikowski J, Breuker K, Höbartner C, Patel DJ, Kreutz C, Micura R. A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class. Angewandte Chemie (International Ed. in English). PMID 26473980 DOI: 10.1002/anie.201506601  1
2015 Chen S, Yang Z, Wilkinson AW, Deshpande AJ, Sidoli S, Krajewski K, Strahl BD, Garcia BA, Armstrong SA, Patel DJ, Gozani O. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Molecular Cell. PMID 26439302 DOI: 10.1016/j.molcel.2015.08.019  1
2015 Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A. Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP. Proceedings of the National Academy of Sciences of the United States of America. 112: E5391-400. PMID 26374839 DOI: 10.1073/pnas.1515737112  1
2015 Teplova M, Farazi TA, Tuschl T, Patel DJ. Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS. Quarterly Reviews of Biophysics. 1-11. PMID 26347403 DOI: 10.1017/S0033583515000207  1
2015 Webster A, Li S, Hur JK, Wachsmuth M, Bois JS, Perkins EM, Patel DJ, Aravin AA. Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper. Molecular Cell. 59: 564-75. PMID 26295961 DOI: 10.1016/j.molcel.2015.07.017  1
2015 Huang H, Strømme CB, Saredi G, Hödl M, Strandsby A, González-Aguilera C, Chen S, Groth A, Patel DJ. A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks. Nature Structural & Molecular Biology. 22: 618-26. PMID 26167883 DOI: 10.1038/nsmb.3055  1
2015 Ren A, Rajashankar KR, Patel DJ. Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism. Structure (London, England : 1993). PMID 26118534 DOI: 10.1016/j.str.2015.05.016  1
2015 Chen S, Rufiange A, Huang H, Rajashankar KR, Nourani A, Patel DJ. Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2. Genes & Development. 29: 1326-40. PMID 26109053 DOI: 10.1101/gad.261115.115  1
2015 Noh KM, Wang H, Kim HR, Wenderski W, Fang F, Li CH, Dewell S, Hughes SH, Melnick AM, Patel DJ, Li H, Allis CD. Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs. Molecular Cell. 59: 89-103. PMID 26073541 DOI: 10.1016/j.molcel.2015.05.017  1
2015 Kim B, Ha M, Loeff L, Chang H, Simanshu DK, Li S, Fareh M, Patel DJ, Joo C, Kim VN. TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms. The Embo Journal. 34: 1801-15. PMID 25979828 DOI: 10.15252/embj.201590931  0.96
2015 Gao P, Patel DJ. V-cGAPs: attenuators of 3'3'-cGAMP signaling. Cell Research. 25: 529-30. PMID 25906992 DOI: 10.1038/cr.2015.48  0.96
2015 Ren A, Wang XC, Kellenberger CA, Rajashankar KR, Jones RA, Hammond MC, Patel DJ. Structural basis for molecular discrimination by a 3',3'-cGAMP sensing riboswitch. Cell Reports. 11: 1-12. PMID 25818298 DOI: 10.1016/j.celrep.2015.03.004  0.96
2015 Malinina L, Simanshu DK, Zhai X, Samygina VR, Kamlekar R, Kenoth R, Ochoa-Lizarralde B, Malakhova ML, Molotkovsky JG, Patel DJ, Brown RE. Sphingolipid transfer proteins defined by the GLTP-fold. Quarterly Reviews of Biophysics. 1-42. PMID 25797198 DOI: 10.1017/S003358351400016X  1
2015 Murn J, Zarnack K, Yang YJ, Durak O, Murphy EA, Cheloufi S, Gonzalez DM, Teplova M, Curk T, Zuber J, Patel DJ, Ule J, Luscombe NM, Tsai LH, Walsh CA, et al. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes & Development. 29: 501-12. PMID 25737280 DOI: 10.1101/gad.258483.115  0.96
2015 Dai Q, Ren A, Westholm JO, Duan H, Patel DJ, Lai EC. Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family. Genes & Development. 29: 48-62. PMID 25561495 DOI: 10.1101/gad.252122.114  0.96
2015 Li H, Zhao S, Patel DJ. Histone recognition by tandem modules and modulation by multiple PTMs Histone Recognition. 149-172. DOI: 10.1007/978-3-319-18102-8_7  1
2014 Lim J, Ha M, Chang H, Kwon SC, Simanshu DK, Patel DJ, Kim VN. Uridylation by TUT4 and TUT7 marks mRNA for degradation. Cell. 159: 1365-76. PMID 25480299 DOI: 10.1016/j.cell.2014.10.055  0.96
2014 Lee M, Choi Y, Kim K, Jin H, Lim J, Nguyen TA, Yang J, Jeong M, Giraldez AJ, Yang H, Patel DJ, Kim VN. Adenylation of maternally inherited microRNAs by Wispy. Molecular Cell. 56: 696-707. PMID 25454948 DOI: 10.1016/j.molcel.2014.10.011  0.96
2014 Ren A, Košuti? M, Rajashankar KR, Frener M, Santner T, Westhof E, Micura R, Patel DJ. In-line alignment and Mg²⁺ coordination at the cleavage site of the env22 twister ribozyme. Nature Communications. 5: 5534. PMID 25410397 DOI: 10.1038/ncomms6534  1
2014 Patel DJ. RNA. Complete pairing not needed. Science (New York, N.Y.). 346: 542-3. PMID 25359948 DOI: 10.1126/science.1262123  1
2014 Kruidenier L, Chung CW, Cheng Z, Liddle J, Che K, Joberty G, Bantscheff M, Bountra C, Bridges A, Diallo H, Eberhard D, Hutchinson S, Jones E, Katso R, Leveridge M, ... ... Patel DJ, et al. Kruidenier et al. reply. Nature. 514: E2. PMID 25279927 DOI: 10.1038/nature13689  0.96
2014 Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ. Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA. Cell Reports. 8: 1668-76. PMID 25199835 DOI: 10.1016/j.celrep.2014.08.010  0.96
2014 Swarts DC, Makarova K, Wang Y, Nakanishi K, Ketting RF, Koonin EV, Patel DJ, van der Oost J. The evolutionary journey of Argonaute proteins. Nature Structural & Molecular Biology. 21: 743-53. PMID 25192263 DOI: 10.1038/nsmb.2879  1
2014 Cheng Z, Cheung P, Kuo AJ, Yukl ET, Wilmot CM, Gozani O, Patel DJ. A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36. Genes & Development. 28: 1758-71. PMID 25128496 DOI: 10.1101/gad.246561.114  1
2014 Ren A, Patel DJ. c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets. Nature Chemical Biology. 10: 780-6. PMID 25086509 DOI: 10.1038/nchembio.1606  1
2014 Le Thomas A, Stuwe E, Li S, Du J, Marinov G, Rozhkov N, Chen YC, Luo Y, Sachidanandam R, Toth KF, Patel D, Aravin AA. Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes & Development. 28: 1667-80. PMID 25085419 DOI: 10.1101/gad.245514.114  0.96
2014 Du J, Patel DJ. Structural biology-based insights into combinatorial readout and crosstalk among epigenetic marks. Biochimica Et Biophysica Acta. 1839: 719-27. PMID 24747177 DOI: 10.1016/j.bbagrm.2014.04.011  0.96
2014 Swarts DC, Jore MM, Westra ER, Zhu Y, Janssen JH, Snijders AP, Wang Y, Patel DJ, Berenguer J, Brouns SJ, van der Oost J. DNA-guided DNA interference by a prokaryotic Argonaute. Nature. 507: 258-61. PMID 24531762 DOI: 10.1038/nature12971  0.96
2014 Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN, Patel DJ. A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer. Molecular Cell. 53: 606-16. PMID 24486018 DOI: 10.1016/j.molcel.2014.01.003  0.96
2014 Simanshu DK, Zhai X, Munch D, Hofius D, Markham JE, Bielawski J, Bielawska A, Malinina L, Molotkovsky JG, Mundy JW, Patel DJ, Brown RE. Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels. Cell Reports. 6: 388-99. PMID 24412362 DOI: 10.1016/j.celrep.2013.12.023  0.96
2014 Sheng G, Zhao H, Wang J, Rao Y, Tian W, Swarts DC, van der Oost J, Patel DJ, Wang Y. Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proceedings of the National Academy of Sciences of the United States of America. 111: 652-7. PMID 24374628 DOI: 10.1073/pnas.1321032111  0.96
2014 Loeff L, Ha M, Kim B, Yeom K, Simanshu DK, Patel DJ, Kim NV, Joo C. Single-Molecule View on the Duality of Microrna Uridylation Biophysical Journal. 106: 698a. DOI: 10.1016/j.bpj.2013.11.3861  0.44
2014 Simanshu DK, Kamlekar RK, Wijesinghe DS, Zou X, Zhai X, Mishra SK, Molotkovsky JG, Malinina L, Hinchcliffe EH, Chalfant CE, Patel DJ, Brown RE. Nonvesicular Trafficking of Ceramide-1-Phosphate by a Lipid Transfer Protein that Regulates Eicosanoid Production Biophysical Journal. 106: 303a. DOI: 10.1016/j.bpj.2013.11.1759  0.44
2014 Ochoa-Lizarralde B, Delgado S, Zhai X, Samygina VR, Popov AN, Cabo-Bilbao A, Pike HM, Molotkovsky JG, Patel DJ, Brown RE, Malinina L. The Hidden Role of Residues in the Recognition Center of Human Glycolipid Transfer Protein (GLTP) Biophysical Journal. 106: 302a-303a. DOI: 10.1016/j.bpj.2013.11.1758  0.4
2014 Zhai X, Simanshu DK, Munch D, Benson LM, Bergen HR, Pike HM, Malinina L, Mundy J, Molotkovsky JG, Patel DJ, Brown RE. Structure-Function Analyses Reveal Arabidopsis Accelerated-Cell-Death11 (Acd11) is a Ceramide-1-Phosphate Transfer Protein that Forms a Gltp-Fold Biophysical Journal. 106: 300a. DOI: 10.1016/j.bpj.2013.11.1745  0.44
2013 Simanshu DK, Yamaguchi Y, Park JH, Inouye M, Patel DJ. Structural basis of mRNA recognition and cleavage by toxin MazF and its regulation by antitoxin MazE in Bacillus subtilis. Molecular Cell. 52: 447-58. PMID 24120662 DOI: 10.1016/j.molcel.2013.09.006  1
2013 Wang Z, Patel DJ. Small molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases. Quarterly Reviews of Biophysics. 46: 349-73. PMID 23991894 DOI: 10.1017/S0033583513000085  1
2013 Gao P, Ascano M, Zillinger T, Wang W, Dai P, Serganov AA, Gaffney BL, Shuman S, Jones RA, Deng L, Hartmann G, Barchet W, Tuschl T, Patel DJ. Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA. Cell. 154: 748-62. PMID 23910378 DOI: 10.1016/j.cell.2013.07.023  1
2013 Simanshu DK, Kamlekar RK, Wijesinghe DS, Zou X, Zhai X, Mishra SK, Molotkovsky JG, Malinina L, Hinchcliffe EH, Chalfant CE, Brown RE, Patel DJ. Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature. 500: 463-7. PMID 23863933 DOI: 10.1038/nature12332  1
2013 Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature. 500: 93-7. PMID 23812588 DOI: 10.1038/nature12287  1
2013 Nakanishi K, Ascano M, Gogakos T, Ishibe-Murakami S, Serganov AA, Briskin D, Morozov P, Tuschl T, Patel DJ. Eukaryote-specific insertion elements control human ARGONAUTE slicer activity. Cell Reports. 3: 1893-900. PMID 23809764 DOI: 10.1016/j.celrep.2013.06.010  1
2013 Gao P, Ascano M, Wu Y, Barchet W, Gaffney BL, Zillinger T, Serganov AA, Liu Y, Jones RA, Hartmann G, Tuschl T, Patel DJ. Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell. 153: 1094-107. PMID 23647843 DOI: 10.1016/j.cell.2013.04.046  1
2013 Patel DJ, Wang Z. Readout of epigenetic modifications. Annual Review of Biochemistry. 82: 81-118. PMID 23642229 DOI: 10.1146/annurev-biochem-072711-165700  1
2013 Shen J, Xia W, Khotskaya YB, Huo L, Nakanishi K, Lim SO, Du Y, Wang Y, Chang WC, Chen CH, Hsu JL, Wu Y, Lam YC, James BP, Liu X, ... ... Patel DJ, et al. EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature. 497: 383-7. PMID 23636329 DOI: 10.1038/nature12080  1
2013 Teplova M, Hafner M, Teplov D, Essig K, Tuschl T, Patel DJ. Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites. Genes & Development. 27: 928-40. PMID 23630077 DOI: 10.1101/gad.216531.113  1
2013 Samygina VR, Ochoa-Lizarralde B, Popov AN, Cabo-Bilbao A, Goni-de-Cerio F, Molotkovsky JG, Patel DJ, Brown RE, Malinina L. Structural insights into lipid-dependent reversible dimerization of human GLTP. Acta Crystallographica. Section D, Biological Crystallography. 69: 603-16. PMID 23519669 DOI: 10.1107/S0907444913000024  1
2013 Dai Q, Ren A, Westholm JO, Serganov AA, Patel DJ, Lai EC. The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors. Genes & Development. 27: 602-14. PMID 23468431 DOI: 10.1101/gad.213314.113  1
2013 Oh YS, Gao P, Lee KW, Ceglia I, Seo JS, Zhang X, Ahn JH, Chait BT, Patel DJ, Kim Y, Greengard P. SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action. Cell. 152: 831-43. PMID 23415230 DOI: 10.1016/j.cell.2013.01.014  1
2013 Khutsishvili I, Zhang N, Marky LA, Crean C, Patel DJ, Geacintov NE, Shafirovich V. Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions. Biochemistry. 52: 1354-63. PMID 23360616 DOI: 10.1021/bi301566v  1
2013 Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG. An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Molecular Cell. 49: 571-82. PMID 23273982 DOI: 10.1016/j.molcel.2012.11.026  1
2013 Kamlekar RK, Simanshu DK, Gao YG, Kenoth R, Pike HM, Prendergast FG, Malinina L, Molotkovsky JG, Venyaminov SY, Patel DJ, Brown RE. The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids. Biochimica Et Biophysica Acta. 1831: 417-27. PMID 23159414 DOI: 10.1016/j.bbalip.2012.10.010  1
2013 Kenoth R, Zou X, Simanshu DK, Zhai X, Pike HM, Molotkovsky JG, Patel DJ, Brown RE. Tryptophan Point Mutants of HET-C2, a Fungal Glycolipid Transfer Protein, Provide Insights into Glycolipid Binding/Transfer and Membrane Interaction Biophysical Journal. 104: 593a. DOI: 10.1016/j.bpj.2012.11.3293  0.44
2012 Kuryavyi V, Cahoon LA, Seifert HS, Patel DJ. RecA-binding pilE G4 sequence essential for pilin antigenic variation forms monomeric and 5' end-stacked dimeric parallel G-quadruplexes. Structure (London, England : 1993). 20: 2090-102. PMID 23085077 DOI: 10.1016/j.str.2012.09.013  1
2012 Elsässer SJ, Huang H, Lewis PW, Chin JW, Allis CD, Patel DJ. DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition. Nature. 491: 560-5. PMID 23075851 DOI: 10.1038/nature11608  1
2012 Kruidenier L, Chung CW, Cheng Z, Liddle J, Che K, Joberty G, Bantscheff M, Bountra C, Bridges A, Diallo H, Eberhard D, Hutchinson S, Jones E, Katso R, Leveridge M, ... ... Patel DJ, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 488: 404-8. PMID 22842901 DOI: 10.1038/nature11262  1
2012 Nakanishi K, Weinberg DE, Bartel DP, Patel DJ. Structure of yeast Argonaute with guide RNA. Nature. 486: 368-74. PMID 22722195 DOI: 10.1038/nature11211  1
2012 Ren A, Rajashankar KR, Patel DJ. Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch. Nature. 486: 85-9. PMID 22678284 DOI: 10.1038/nature11152  1
2012 Ausin I, Greenberg MV, Simanshu DK, Hale CJ, Vashisht AA, Simon SA, Lee TF, Feng S, Española SD, Meyers BC, Wohlschlegel JA, Patel DJ, Jacobsen SE. INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America. 109: 8374-81. PMID 22592791 DOI: 10.1073/pnas.1206638109  0.44
2012 Serganov A, Patel DJ. Molecular recognition and function of riboswitches. Current Opinion in Structural Biology. 22: 279-86. PMID 22579413 DOI: 10.1016/j.sbi.2012.04.005  1
2012 Serganov A, Patel DJ. Metabolite recognition principles and molecular mechanisms underlying riboswitch function. Annual Review of Biophysics. 41: 343-70. PMID 22577823 DOI: 10.1146/annurev-biophys-101211-113224  1
2012 Kuo AJ, Song J, Cheung P, Ishibe-Murakami S, Yamazoe S, Chen JK, Patel DJ, Gozani O. The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome. Nature. 484: 115-9. PMID 22398447 DOI: 10.1038/nature10956  1
2012 Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, ... Patel DJ, et al. RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction. Rna (New York, N.Y.). 18: 610-25. PMID 22361291 DOI: 10.1261/rna.031054.111  1
2012 Song J, Teplova M, Ishibe-Murakami S, Patel DJ. Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation. Science (New York, N.Y.). 335: 709-12. PMID 22323818 DOI: 10.1126/science.1214453  1
2012 Du J, Kelly AE, Funabiki H, Patel DJ. Structural basis for recognition of H3T3ph and Smac/DIABLO N-terminal peptides by human Survivin. Structure (London, England : 1993). 20: 185-95. PMID 22244766 DOI: 10.1016/j.str.2011.12.001  1
2012 Kanth Kamlekar R, Gao Y, Simanshu D, Prendergast FG, Venyaminov SY, Malinina L, Molotkovsky JG, Patel DJ, Brown RE. Glycolipid Transfer Protein (GLTP) Domain of Phosphoinositol 4-Phosphate Adaptor Protein-2 (FAPP2): Lipid Transfer Specificity and Physical Features Biophysical Journal. 102: 495a. DOI: 10.1016/j.bpj.2011.11.2713  0.4
2011 Xi Q, Wang Z, Zaromytidou AI, Zhang XH, Chow-Tsang LF, Liu JX, Kim H, Barlas A, Manova-Todorova K, Kaartinen V, Studer L, Mark W, Patel DJ, Massagué J. A poised chromatin platform for TGF-β access to master regulators. Cell. 147: 1511-24. PMID 22196728 DOI: 10.1016/j.cell.2011.11.032  1
2011 Samygina VR, Popov AN, Cabo-Bilbao A, Ochoa-Lizarralde B, Goni-de-Cerio F, Zhai X, Molotkovsky JG, Patel DJ, Brown RE, Malinina L. Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein. Structure (London, England : 1993). 19: 1644-54. PMID 22078563 DOI: 10.1016/j.str.2011.09.011  1
2011 Huang L, Ishibe-Murakami S, Patel DJ, Serganov A. Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch. Proceedings of the National Academy of Sciences of the United States of America. 108: 14801-6. PMID 21873197 DOI: 10.1073/pnas.1111701108  1
2011 Pikovskaya O, Polonskaia A, Patel DJ, Serganov A. Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch. Nature Chemical Biology. 7: 748-55. PMID 21841796 DOI: 10.1038/nchembio.631  1
2011 Teplova M, Wohlbold L, Khin NW, Izaurralde E, Patel DJ. Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nature Structural & Molecular Biology. 18: 990-8. PMID 21822283 DOI: 10.1038/nsmb.2094  1
2011 Weinberg DE, Nakanishi K, Patel DJ, Bartel DP. The inside-out mechanism of Dicers from budding yeasts. Cell. 146: 262-76. PMID 21784247 DOI: 10.1016/j.cell.2011.06.021  1
2011 Rajakumara E, Wang Z, Ma H, Hu L, Chen H, Lin Y, Guo R, Wu F, Li H, Lan F, Shi YG, Xu Y, Patel DJ, Shi Y. PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression. Molecular Cell. 43: 275-84. PMID 21777816 DOI: 10.1016/j.molcel.2011.07.006  1
2011 Reeves DA, Mu H, Kropachev K, Cai Y, Ding S, Kolbanovskiy A, Kolbanovskiy M, Chen Y, Krzeminski J, Amin S, Patel DJ, Broyde S, Geacintov NE. Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions. Nucleic Acids Research. 39: 8752-64. PMID 21764772 DOI: 10.1093/nar/gkr537  1
2011 Park JE, Heo I, Tian Y, Simanshu DK, Chang H, Jee D, Patel DJ, Kim VN. Dicer recognizes the 5' end of RNA for efficient and accurate processing. Nature. 475: 201-5. PMID 21753850 DOI: 10.1038/nature10198  1
2011 Teplova M, Malinina L, Darnell JC, Song J, Lu M, Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB, Patel DJ. Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. Structure (London, England : 1993). 19: 930-44. PMID 21742260 DOI: 10.1016/j.str.2011.05.002  1
2011 Iwase S, Xiang B, Ghosh S, Ren T, Lewis PW, Cochrane JC, Allis CD, Picketts DJ, Patel DJ, Li H, Shi Y. ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nature Structural & Molecular Biology. 18: 769-76. PMID 21666679 DOI: 10.1038/nsmb.2062  1
2011 Rechkoblit O, Delaney JC, Essigmann JM, Patel DJ. Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure (London, England : 1993). 19: 821-32. PMID 21645853 DOI: 10.1016/j.str.2011.03.020  1
2011 Phan AT, Kuryavyi V, Darnell JC, Serganov A, Majumdar A, Ilin S, Raslin T, Polonskaia A, Chen C, Clain D, Darnell RB, Patel DJ. Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. Nature Structural & Molecular Biology. 18: 796-804. PMID 21642970 DOI: 10.1038/nsmb.2064  1
2011 Ruthenburg AJ, Li H, Milne TA, Dewell S, McGinty RK, Yuen M, Ueberheide B, Dou Y, Muir TW, Patel DJ, Allis CD. Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions. Cell. 145: 692-706. PMID 21596426 DOI: 10.1016/j.cell.2011.03.053  1
2011 Kenoth R, Kamlekar RK, Simanshu DK, Gao Y, Malinina L, Prendergast FG, Molotkovsky JG, Patel DJ, Venyaminov SY, Brown RE. Conformational folding and stability of the HET-C2 glycolipid transfer protein fold: does a molten globule-like state regulate activity? Biochemistry. 50: 5163-71. PMID 21553912 DOI: 10.1021/bi200382c  1
2011 Tian Y, Simanshu DK, Ascano M, Diaz-Avalos R, Park AY, Juranek SA, Rice WJ, Yin Q, Robinson CV, Tuschl T, Patel DJ. Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex. Nature Structural & Molecular Biology. 18: 658-64. PMID 21552261 DOI: 10.1038/nsmb.2069  1
2011 Wang Z, Patel DJ. Combinatorial readout of dual histone modifications by paired chromatin-associated modules. The Journal of Biological Chemistry. 286: 18363-8. PMID 21454653 DOI: 10.1074/jbc.R111.219139  1
2011 Rajakumara E, Law JA, Simanshu DK, Voigt P, Johnson LM, Reinberg D, Patel DJ, Jacobsen SE. A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes & Development. 25: 137-52. PMID 21245167 DOI: 10.1101/gad.1980311  0.44
2011 Tian Y, Simanshu DK, Ma JB, Patel DJ. Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proceedings of the National Academy of Sciences of the United States of America. 108: 903-10. PMID 21193640 DOI: 10.1073/pnas.1017762108  1
2011 Song J, Rechkoblit O, Bestor TH, Patel DJ. Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science (New York, N.Y.). 331: 1036-40. PMID 21163962 DOI: 10.1126/science.1195380  1
2011 Rüdel S, Wang Y, Lenobel R, Körner R, Hsiao HH, Urlaub H, Patel D, Meister G. Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Research. 39: 2330-43. PMID 21071408 DOI: 10.1093/nar/gkq1032  1
2011 Mallikaratchy PR, Ruggiero A, Gardner JR, Kuryavyi V, Maguire WF, Heaney ML, McDevitt MR, Patel DJ, Scheinberg DA. A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia. Nucleic Acids Research. 39: 2458-69. PMID 21030439 DOI: 10.1093/nar/gkq996  1
2011 Malinina L, Samygina V, Cabo-Bilbao A, Popov AN, Ochoa-Lizarralde B, Patel DJ, Brown RE. Sulfatide selective human glycolipid transfer protein Acta Crystallographica Section a Foundations of Crystallography. 67: C289-C289. DOI: 10.1107/S0108767311092774  0.4
2011 Broyde S, Wang L, Cai Y, Jia L, Shapiro R, Patel DJ, Geacintov NE. Covalent polycyclic aromatic hydrocarbon-DNA adducts: Carcinogenicity, structure, and function Current Cancer Research. 6: 181-207. DOI: 10.1007/978-1-61737-995-6_9  1
2010 Tsai WW, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S, Tsai CY, Shi X, Schwarzer D, Plunkett W, Aronow B, Gozani O, Fischle W, Hung MC, Patel DJ, et al. TRIM24 links a non-canonical histone signature to breast cancer. Nature. 468: 927-32. PMID 21164480 DOI: 10.1038/nature09542  1
2010 Huang L, Serganov A, Patel DJ. Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Molecular Cell. 40: 774-86. PMID 21145485 DOI: 10.1016/j.molcel.2010.11.026  1
2010 Kamlekar RK, Gao Y, Kenoth R, Molotkovsky JG, Prendergast FG, Malinina L, Patel DJ, Wessels WS, Venyaminov SY, Brown RE. Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold. Biophysical Journal. 99: 2626-35. PMID 20959104 DOI: 10.1016/j.bpj.2010.08.038  1
2010 Teplova M, Song J, Gaw HY, Teplov A, Patel DJ. Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1. Structure (London, England : 1993). 18: 1364-77. PMID 20947024 DOI: 10.1016/j.str.2010.06.018  1
2010 Cai Y, Patel DJ, Broyde S, Geacintov NE. Base sequence context effects on nucleotide excision repair. Journal of Nucleic Acids. 2010. PMID 20871811 DOI: 10.4061/2010/174252  1
2010 Wang Y, Ludwig J, Schuberth C, Goldeck M, Schlee M, Li H, Juranek S, Sheng G, Micura R, Tuschl T, Hartmann G, Patel DJ. Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I. Nature Structural & Molecular Biology. 17: 781-7. PMID 20581823 DOI: 10.1038/nsmb.1863  1
2010 Broyde S, Patel DJ. DNA repair: How to accurately bypass damage. Nature. 465: 1023-4. PMID 20577203 DOI: 10.1038/4651023a  1
2010 Kuryavyi V, Phan AT, Patel DJ. Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter. Nucleic Acids Research. 38: 6757-73. PMID 20566478 DOI: 10.1093/nar/gkq558  1
2010 Wang Z, Song J, Milne TA, Wang GG, Li H, Allis CD, Patel DJ. Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell. 141: 1183-94. PMID 20541251 DOI: 10.1016/j.cell.2010.05.016  1
2010 Cai Y, Kropachev K, Xu R, Tang Y, Kolbanovskii M, Kolbanovskii A, Amin S, Patel DJ, Broyde S, Geacintov NE. Distant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion. Journal of Molecular Biology. 399: 397-409. PMID 20399214 DOI: 10.1016/j.jmb.2010.04.004  1
2010 Kenoth R, Simanshu DK, Kamlekar RK, Pike HM, Molotkovsky JG, Benson LM, Bergen HR, Prendergast FG, Malinina L, Venyaminov SY, Patel DJ, Brown RE. Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. The Journal of Biological Chemistry. 285: 13066-78. PMID 20164530 DOI: 10.1074/jbc.M109.093203  1
2010 Rechkoblit O, Kolbanovskiy A, Malinina L, Geacintov NE, Broyde S, Patel DJ. Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nature Structural & Molecular Biology. 17: 379-88. PMID 20154704 DOI: 10.1038/nsmb.1771  1
2010 Kuryavyi V, Patel DJ. Solution structure of a unique G-quadruplex scaffold adopted by a guanosine-rich human intronic sequence. Structure (London, England : 1993). 18: 73-82. PMID 20152154 DOI: 10.1016/j.str.2009.10.015  1
2010 Shen C, Patel DJ. Biogenic amine-ionophore interactions: Structure and dynamics of lasalocid (X537A) complexes with phenethylamines and catecholamines in nonpolar solution. Proceedings of the National Academy of Sciences of the United States of America. 74: 4734-8. PMID 16592462 DOI: 10.1073/pnas.74.11.4734  0.36
2010 Telvekar VN, Patel DJ, Jadhav NC, Mishra SJ. Three-dimensional QSAR and pharmacophore mapping of biphenyl benzoic acid derivatives as selective human β3-adrenergic receptor agonists Medicinal Chemistry Research. 19: 1174-1190. DOI: 10.1007/s00044-009-9261-1  0.56
2010 Majumdar A, Patel DJ. ChemInform Abstract: Identifying Hydrogen Bond Alignments in Multistranded DNA Architectures by NMR Cheminform. 33: no-no. DOI: 10.1002/chin.200217296  0.8
2010 Broyde S, Wang L, Patel DJ, Geacintov NE. Elucidating Structure-Function Relationships in Bulky DNA Lesions: From Solution Structures to Polymerases The Chemical Biology of Dna Damage. 331-352. DOI: 10.1002/9783527630110.ch14  1
2010 Cai Y, Kropachev K, Kolbanovskiy M, Kolbanovskiy A, Broyde S, Patel DJ, Geacintov NE. Recognition and Removal of Bulky DNA Lesions by the Nucleotide Excision Repair System The Chemical Biology of Dna Damage. 261-298. DOI: 10.1002/9783527630110.ch12  1
2009 Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ. Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature. 461: 754-61. PMID 19812667 DOI: 10.1038/nature08434  1
2009 Serganov A, Patel DJ. Amino acid recognition and gene regulation by riboswitches. Biochimica Et Biophysica Acta. 1789: 592-611. PMID 19619684 DOI: 10.1016/j.bbagrm.2009.07.002  1
2009 Zhang N, Ding S, Kolbanovskiy A, Shastry A, Kuzmin VA, Bolton JL, Patel DJ, Broyde S, Geacintov NE. NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms. Biochemistry. 48: 7098-109. PMID 19527068 DOI: 10.1021/bi9006429  1
2009 Westhof E, Patel DJ. Nucleic acids: how high resolution structural biology help us to understand Darwinian evolution. Current Opinion in Structural Biology. 19: 235-8. PMID 19482468 DOI: 10.1016/j.sbi.2009.04.004  1
2009 Rechkoblit O, Malinina L, Cheng Y, Geacintov NE, Broyde S, Patel DJ. Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure (London, England : 1993). 17: 725-36. PMID 19446528 DOI: 10.1016/j.str.2009.03.011  1
2009 Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature. 459: 847-51. PMID 19430464 DOI: 10.1038/nature08036  1
2009 Li H, Motamedi MR, Yip CK, Wang Z, Walz T, Patel DJ, Moazed D. An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Molecular Cell. 34: 155-67. PMID 19394293 DOI: 10.1016/j.molcel.2009.02.032  1
2009 Pikovskaya O, Serganov AA, Polonskaia A, Serganov A, Patel DJ. Preparation and crystallization of riboswitch-ligand complexes Methods in Molecular Biology (Clifton, N.J.). 540: 115-128. PMID 19381556 DOI: 10.1007/978-1-59745-558-9_9  1
2009 Lim KW, Amrane S, Bouaziz S, Xu W, Mu Y, Patel DJ, Luu KN, Phan AT. Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers. Journal of the American Chemical Society. 131: 4301-9. PMID 19271707 DOI: 10.1021/ja807503g  1
2009 Zhai X, Malakhova ML, Pike HM, Benson LM, Bergen HR, Sugár IP, Malinina L, Patel DJ, Brown RE. Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: insights into glycolipid binding affinity. The Journal of Biological Chemistry. 284: 13620-8. PMID 19270338 DOI: 10.1074/jbc.M809089200  1
2009 Zhao Q, Rank G, Tan YT, Li H, Moritz RL, Simpson RJ, Cerruti L, Curtis DJ, Patel DJ, Allis CD, Cunningham JM, Jane SM. PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing. Nature Structural & Molecular Biology. 16: 304-11. PMID 19234465 DOI: 10.1038/nsmb.1568  1
2009 Serganov A, Huang L, Patel DJ. Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch Nature. 458: 233-237. PMID 19169240 DOI: 10.1038/nature07642  1
2009 Kropachev K, Kolbanovskii M, Cai Y, Rodríguez F, Kolbanovskii A, Liu Y, Zhang L, Amin S, Patel D, Broyde S, Geacintov NE. The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions. Journal of Molecular Biology. 386: 1193-203. PMID 19162041 DOI: 10.1016/j.jmb.2008.12.082  1
2009 Xiao A, Li H, Shechter D, Ahn SH, Fabrizio LA, Erdjument-Bromage H, Ishibe-Murakami S, Wang B, Tempst P, Hofmann K, Patel DJ, Elledge SJ, Allis CD. WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity. Nature. 457: 57-62. PMID 19092802 DOI: 10.1038/nature07668  1
2009 Cai Y, Patel DJ, Geacintov NE, Broyde S. Differential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signals. Journal of Molecular Biology. 385: 30-44. PMID 18948114 DOI: 10.1016/j.jmb.2008.09.087  1
2008 Wang Y, Juranek S, Li H, Sheng G, Tuschl T, Patel DJ. Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature. 456: 921-6. PMID 19092929 DOI: 10.1038/nature07666  1
2008 Teplova M, Patel DJ. Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1. Nature Structural & Molecular Biology. 15: 1343-51. PMID 19043415 DOI: 10.1038/nsmb.1519  0.56
2008 Patel DJ. Structural biology of riboswitch-mediated gene regulation and argonaute-mediated gene silencing Nucleic Acids Symposium Series (2004). 1. PMID 18776223 DOI: 10.1093/nass/nrn001  1
2008 Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ. Structure of the guide-strand-containing argonaute silencing complex. Nature. 456: 209-13. PMID 18754009 DOI: 10.1038/nature07315  1
2008 Broyde S, Wang L, Rechkoblit O, Geacintov NE, Patel DJ. Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. Trends in Biochemical Sciences. 33: 209-19. PMID 18407502 DOI: 10.1016/j.tibs.2008.02.004  1
2008 Serganov A, Patel DJ. Towards deciphering the principles underlying an mRNA recognition code. Current Opinion in Structural Biology. 18: 120-9. PMID 18255277 DOI: 10.1016/j.sbi.2007.12.006  0.6
2008 Broyde S, Wang L, Zhang L, Rechkoblit O, Geacintov NE, Patel DJ. DNA adduct structure-function relationships: comparing solution with polymerase structures. Chemical Research in Toxicology. 21: 45-52. PMID 18052109 DOI: 10.1021/tx700193x  1
2007 Li H, Fischle W, Wang W, Duncan EM, Liang L, Murakami-Ishibe S, Allis CD, Patel DJ. Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger. Molecular Cell. 28: 677-91. PMID 18042461 DOI: 10.1016/j.molcel.2007.10.023  1
2007 Ruthenburg AJ, Li H, Patel DJ, Allis CD. Multivalent engagement of chromatin modifications by linked binding modules. Nature Reviews. Molecular Cell Biology. 8: 983-94. PMID 18037899 DOI: 10.1038/nrm2298  1
2007 Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ. How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nature Structural & Molecular Biology. 14: 1025-40. PMID 17984965 DOI: 10.1038/nsmb1338  1
2007 Cai Y, Patel DJ, Geacintov NE, Broyde S. Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair. Journal of Molecular Biology. 374: 292-305. PMID 17942115 DOI: 10.1016/j.jmb.2007.09.034  1
2007 Patel DJ, Phan AT, Kuryavyi V. Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Research. 35: 7429-55. PMID 17913750 DOI: 10.1093/nar/gkm711  0.4
2007 Phan AT, Kuryavyi V, Luu KN, Patel DJ. Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Research. 35: 6517-25. PMID 17895279 DOI: 10.1093/nar/gkm706  0.4
2007 Serganov A, Patel DJ. Ribozymes, riboswitches and beyond: regulation of gene expression without proteins. Nature Reviews. Genetics. 8: 776-90. PMID 17846637 DOI: 10.1038/nrg2172  0.6
2007 Bailor MH, Musselman C, Hansen AL, Gulati K, Patel DJ, Al-Hashimi HM. Characterizing the relative orientation and dynamics of RNA A-form helices using NMR residual dipolar couplings. Nature Protocols. 2: 1536-46. PMID 17571061 DOI: 10.1038/nprot.2007.221  1
2007 Phan AT, Kuryavyi V, Burge S, Neidle S, Patel DJ. Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter. Journal of the American Chemical Society. 129: 4386-92. PMID 17362008 DOI: 10.1021/ja068739h  1
2007 Rodríguez FA, Cai Y, Lin C, Tang Y, Kolbanovskiy A, Amin S, Patel DJ, Broyde S, Geacintov NE. Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context. Nucleic Acids Research. 35: 1555-68. PMID 17287290 DOI: 10.1093/nar/gkm022  1
2007 Hermann T, Tereshko V, Skripkin E, Patel DJ. Apramycin recognition by the human ribosomal decoding site. Blood Cells, Molecules & Diseases. 38: 193-8. PMID 17258916 DOI: 10.1016/j.bcmd.2006.11.006  0.32
2006 Patel DJ, Ma JB, Yuan YR, Ye K, Pei Y, Kuryavyi V, Malinina L, Meister G, Tuschl T. Structural biology of RNA silencing and its functional implications. Cold Spring Harbor Symposia On Quantitative Biology. 71: 81-93. PMID 17381284 DOI: 10.1101/sqb.2006.71.053  1
2006 Zhang X, Yuan YR, Pei Y, Lin SS, Tuschl T, Patel DJ, Chua NH. Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. Genes & Development. 20: 3255-68. PMID 17158744 DOI: 10.1101/gad.1495506  1
2006 Taverna SD, Ilin S, Rogers RS, Tanny JC, Lavender H, Li H, Baker L, Boyle J, Blair LP, Chait BT, Patel DJ, Aitchison JD, Tackett AJ, Allis CD. Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Molecular Cell. 24: 785-96. PMID 17157260 DOI: 10.1016/j.molcel.2006.10.026  1
2006 Malinina L, Malakhova ML, Kanack AT, Lu M, Abagyan R, Brown RE, Patel DJ. The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. Plos Biology. 4: e362. PMID 17105344 DOI: 10.1371/journal.pbio.0040362  1
2006 Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ. A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA. Structure (London, England : 1993). 14: 1557-65. PMID 17027504 DOI: 10.1016/j.str.2006.08.009  1
2006 Luu KN, Phan AT, Kuryavyi V, Lacroix L, Patel DJ. Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold. Journal of the American Chemical Society. 128: 9963-70. PMID 16866556 DOI: 10.1021/ja062791w  0.4
2006 Ruthenburg AJ, Wang W, Graybosch DM, Li H, Allis CD, Patel DJ, Verdine GL. Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nature Structural & Molecular Biology. 13: 704-12. PMID 16829959 DOI: 10.1038/nsmb1119  1
2006 Zhang L, Rechkoblit O, Wang L, Patel DJ, Shapiro R, Broyde S. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies. Nucleic Acids Research. 34: 3326-37. PMID 16820532 DOI: 10.1093/nar/gkl425  1
2006 Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature. 441: 1167-71. PMID 16728979 DOI: 10.1038/nature04740  1
2006 Li H, Ilin S, Wang W, Duncan EM, Wysocka J, Allis CD, Patel DJ. Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature. 442: 91-5. PMID 16728978 DOI: 10.1038/nature04802  1
2006 Phan AT, Kuryavyi V, Patel DJ. DNA architecture: from G to Z. Current Opinion in Structural Biology. 16: 288-98. PMID 16714104 DOI: 10.1016/j.sbi.2006.05.011  0.4
2006 Wombacher R, Keiper S, Suhm S, Serganov A, Patel DJ, Jäschke A. Control of stereoselectivity in an enzymatic reaction by backdoor access. Angewandte Chemie (International Ed. in English). 45: 2469-72. PMID 16528762 DOI: 10.1002/anie.200503280  0.6
2006 Teplova M, Yuan YR, Phan AT, Malinina L, Ilin S, Teplov A, Patel DJ. Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen. Molecular Cell. 21: 75-85. PMID 16387655 DOI: 10.1016/j.molcel.2005.10.027  0.56
2006 Rechkoblit O, Malinina L, Cheng Y, Kuryavyi V, Broyde S, Geacintov NE, Patel DJ. Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. Plos Biology. 4: e11. PMID 16379496 DOI: 10.1371/journal.pbio.0040011  1
2006 Wombacher R, Keiper S, Suhm S, Serganov A, Patel DJ, Jäschke A. Kontrolle der Stereoselektivität einer enzymatischen Reaktion “durch die Hintertür” Angewandte Chemie. 118: 2529-2533. DOI: 10.1002/ange.200503280  0.6
2005 Phan AT, Kuryavyi V, Gaw HY, Patel DJ. Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nature Chemical Biology. 1: 167-73. PMID 16408022 DOI: 10.1038/nchembio723  0.4
2005 Ye K, Patel DJ. RNA silencing suppressor p21 of Beet yellows virus forms an RNA binding octameric ring structure Structure. 13: 1375-1384. PMID 16154094 DOI: 10.1016/j.str.2005.06.017  1
2005 Yuan YR, Pei Y, Ma JB, Kuryavyi V, Zhadina M, Meister G, Chen HY, Dauter Z, Tuschl T, Patel DJ. Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage. Molecular Cell. 19: 405-19. PMID 16061186 DOI: 10.1016/j.molcel.2005.07.011  1
2005 Malakhova ML, Malinina L, Pike HM, Kanack AT, Patel DJ, Brown RE. Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex. The Journal of Biological Chemistry. 280: 26312-20. PMID 15901739 DOI: 10.1074/jbc.M500481200  0.4
2005 Pitt SW, Zhang Q, Patel DJ, Al-Hashimi HM. Evidence that electrostatic interactions dictate the ligand-induced arrest of RNA global flexibility. Angewandte Chemie (International Ed. in English). 44: 3412-5. PMID 15861447 DOI: 10.1002/anie.200500075  1
2005 Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel DJ. Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature. 434: 666-70. PMID 15800629 DOI: 10.1038/nature03514  1
2005 Wang L, Wu M, Yan SF, Patel DJ, Geacintov NE, Broyde S. Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations. Chemical Research in Toxicology. 18: 441-56. PMID 15777084 DOI: 10.1021/tx049786v  1
2005 Zhang N, Lin C, Huang X, Kolbanovskiy A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement. Journal of Molecular Biology. 346: 951-65. PMID 15701509 DOI: 10.1016/j.jmb.2004.12.027  1
2005 Phan AT, Kuryavyi V, Ma JB, Faure A, Andréola ML, Patel DJ. An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase. Proceedings of the National Academy of Sciences of the United States of America. 102: 634-9. PMID 15637158 DOI: 10.1073/pnas.0406278102  1
2005 Phan AT, Kuryavyi V, Gaw HY, Patel DJ. Erratum: Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter Nature Chemical Biology. 1: 234-234. DOI: 10.1038/nchembio0905-234b  0.4
2004 Serganov A, Yuan YR, Pikovskaya O, Polonskaia A, Malinina L, Phan AT, Hobartner C, Micura R, Breaker RR, Patel DJ. Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs. Chemistry & Biology. 11: 1729-41. PMID 15610857 DOI: 10.1016/j.chembiol.2004.11.018  1
2004 Wu M, Yan SF, Tan J, Patel DJ, Geacintov NE, Broyde S. Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2807-18. PMID 15353316 DOI: 10.2741/1438  1
2004 Cheng Y, Sequeira SM, Malinina L, Tereshko V, Söllner TH, Patel DJ. Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain. Protein Science : a Publication of the Protein Society. 13: 2665-72. PMID 15340165 DOI: 10.1110/ps.04832604  0.4
2004 Malinina L, Malakhova ML, Teplov A, Brown RE, Patel DJ. Structural basis for glycosphingolipid transfer specificity. Nature. 430: 1048-53. PMID 15329726 DOI: 10.1038/nature02856  0.4
2004 Ma JB, Ye K, Patel DJ. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature. 429: 318-22. PMID 15152257 DOI: 10.1038/nature02519  1
2004 Mathy N, Pellegrini O, Serganov A, Patel DJ, Ehresmann C, Portier C. Specific recognition of rpsO mRNA and 16S rRNA by Escherichia coli ribosomal protein S15 relies on both mimicry and site differentiation Molecular Microbiology. 52: 661-675. PMID 15101974 DOI: 10.1111/j.1365-2958.2004.04005.x  1
2004 Pitt SW, Majumdar A, Serganov A, Patel DJ, Al-Hashimi HM. Argininamide binding arrests global motions in HIV-1 TAR RNA: comparison with Mg2+-induced conformational stabilization. Journal of Molecular Biology. 338: 7-16. PMID 15050819 DOI: 10.1016/j.jmb.2004.02.031  1
2003 Al-Hashimi HM, Pitt SW, Majumdar A, Xu W, Patel DJ. Mg2+-induced variations in the conformation and dynamics of HIV-1 TAR RNA probed using NMR residual dipolar couplings. Journal of Molecular Biology. 329: 867-73. PMID 12798678 DOI: 10.1016/S0022-2836(03)00517-5  1
2003 Serganov A, Polonskaia A, Ehresmann B, Ehresmann C, Patel DJ. Ribosomal protein S15 represses its own translation via adaptation of an rRNA-like fold within its mRNA. The Embo Journal. 22: 1898-908. PMID 12682022 DOI: 10.1093/emboj/cdg170  0.6
2003 Yan S, Wu M, Patel DJ, Geacintov NE, Broyde S. Simulating structural and thermodynamic properties of carcinogen-damaged DNA. Biophysical Journal. 84: 2137-48. PMID 12668423 DOI: 10.1016/S0006-3495(03)75020-6  1
2003 Tereshko V, Skripkin E, Patel DJ. Encapsulating streptomycin within a small 40-mer RNA. Chemistry & Biology. 10: 175-87. PMID 12618190 DOI: 10.1016/S1074-5521(03)00024-3  0.32
2002 Palmer AG, Patel DJ. Kurt Wüthrich and NMR of biological macromolecules. Structure (London, England : 1993). 10: 1603-4. PMID 12467565 DOI: 10.1016/S0969-2126(02)00915-2  1
2002 Ye K, Serganov A, Hu W, Garber M, Patel DJ. Ribosome-associated factor Y adopts a fold resembling a double-stranded RNA binding domain scaffold. European Journal of Biochemistry. 269: 5182-91. PMID 12392550 DOI: 10.1046/j.1432-1033.2002.03222.x  0.8
2002 Geacintov NE, Broyde S, Buterin T, Naegeli H, Wu M, Yan S, Patel DJ. Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery. Biopolymers. 65: 202-10. PMID 12228925 DOI: 10.1002/bip.10239  1
2002 Wu M, Yan S, Patel DJ, Geacintov NE, Broyde S. Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability. Nucleic Acids Research. 30: 3422-32. PMID 12140327 DOI: 10.1093/nar/gkf427  1
2002 Patel DJ. Structural biology: A molecular propeller Nature. 417: 807-808. PMID 12075337 DOI: 10.1038/417807a  1
2002 Al-Hashimi HM, Gorin A, Majumdar A, Gosser Y, Patel DJ. Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings. Journal of Molecular Biology. 318: 637-49. PMID 12054812 DOI: 10.1016/S0022-2836(02)00160-2  1
2002 Al-Hashimi HM, Patel DJ. Residual dipolar couplings: synergy between NMR and structural genomics. Journal of Biomolecular Nmr. 22: 1-8. PMID 11885976 DOI: 10.1023/A:1013801714041  1
2002 Majumdar A, Gosser Y, Patel DJ. 1H-1H correlations across N-H...N hydrogen bonds in nucleic acids. Journal of Biomolecular Nmr. 21: 289-306. PMID 11824750 DOI: 10.1023/A:1013340227140  0.8
2002 Majumdar A, Patel DJ. Identifying hydrogen bond alignments in multistranded DNA architectures by NMR. Accounts of Chemical Research. 35: 1-11. PMID 11790083 DOI: 10.1021/ar010097+  0.8
2002 Al-Hashimi HM, Gosser Y, Gorin A, Hu W, Majumdar A, Patel DJ. Concerted motions in HIV-1 TAR RNA may allow access to bound state conformations: RNA dynamics from NMR residual dipolar couplings. Journal of Molecular Biology. 315: 95-102. PMID 11779230 DOI: 10.1006/jmbi.2001.5235  1
2002 Nonin-Lecomte S, Lin CH, Patel DJ. Additional hydrogen bonds and base-pair kinetics in the symmetrical AMP-DNA aptamer complex. Biophysical Journal. 81: 3422-31. PMID 11721004 DOI: 10.1016/S0006-3495(01)75974-7  0.36
2002 Hu W, Gosser YQ, Xu W, Patel DJ. Novel 2D and 3D multiple-quantum bi-directional HCNCH experiments for the correlation of ribose and base protons/carbons in 13C/15N labeled RNA. Journal of Biomolecular Nmr. 20: 167-72. PMID 11495247 DOI: 10.1023/A:1011226415824  0.8
2001 Wu M, Yan S, Patel DJ, Geacintov NE, Broyde S. Cyclohexene ring and Fjord region twist inversion in stereoisomeric DNA adducts of enantiomeric benzo[c]phenanthrene diol epoxides. Chemical Research in Toxicology. 14: 1629-42. PMID 11743746 DOI: 10.1021/tx010152n  1
2001 Zhang N, Gorin A, Majumdar A, Kettani A, Chernichenko N, Skripkin E, Patel DJ. Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs. Journal of Molecular Biology. 312: 1073-88. PMID 11580251 DOI: 10.1006/jmbi.2001.5002  0.8
2001 Zhang N, Gorin A, Majumdar A, Kettani A, Chernichenko N, Skripkin E, Patel DJ. V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads. Journal of Molecular Biology. 311: 1063-79. PMID 11531340 DOI: 10.1006/jmbi.2001.4916  0.8
2001 Al-Hashimi HM, Gorin A, Majumdar A, Patel DJ. Alignment of the HTLV-I Rex peptide bound to its target RNA aptamer from magnetic field-induced residual dipolar couplings and intermolecular hydrogen bonds. Journal of the American Chemical Society. 123: 3179-80. PMID 11457047 DOI: 10.1021/ja004133w  1
2001 Al-Hashimi HM, Majumdar A, Gorin A, Kettani A, Skripkin E, Patel DJ. Field- and phage-induced dipolar couplings in a homodimeric DNA quadruplex: relative orientation of G.(C-A) triad and G-tetrad motifs and direct determination of C2 symmetry axis orientation. Journal of the American Chemical Society. 123: 633-40. PMID 11456575 DOI: 10.1021/ja003379y  1
2001 Kuryavyi V, Majumdar A, Shallop A, Chernichenko N, Skripkin E, Jones R, Patel DJ. A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple. Journal of Molecular Biology. 310: 181-94. PMID 11419945 DOI: 10.1006/jmbi.2001.4759  0.8
2001 Al-Hashimi HM, Tolman JR, Majumdar A, Gorin A, Patel DJ. Determining stoichiometry in homomultimeric nucleic acid complexes using magnetic field induced residual dipolar couplings. Journal of the American Chemical Society. 123: 5806-7. PMID 11403617 DOI: 10.1021/ja0105865  1
2001 Majumdar A, Kettani A, Skripkin E, Patel DJ. Pulse sequences for detection of NH2...N hydrogen bonds in sheared G . A mismatches via remote, non-exchangeable protons. Journal of Biomolecular Nmr. 19: 103-13. PMID 11256807 DOI: 10.1023/A:1008311624772  0.8
2001 Lin CH, Huang X, Kolbanovskii A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity. Journal of Molecular Biology. 306: 1059-80. PMID 11237618 DOI: 10.1006/jmbi.2001.4425  1
2001 Gosser Y, Hermann T, Majumdar A, Hu W, Frederick R, Jiang F, Xu W, Patel DJ. Peptide-triggered conformational switch in HIV-1 RRE RNA complexes. Nature Structural Biology. 8: 146-50. PMID 11175904 DOI: 10.1038/84138  0.8
2001 Liu A, Hu W, Majumdar A, Rosen MK, Patel DJ. NMR detection of side chain-side chain hydrogen bonding interactions in 13C/15N-labeled proteins. Journal of Biomolecular Nmr. 17: 305-10. PMID 11014594 DOI: 10.1023/A:1008390813387  0.8
2001 Liu A, Hu W, Majumdar A, Rosen MK, Patel DJ. Detection of very weak side chain-main chain hydrogen bonding interactions in medium-size 13C/15N-labeled proteins by sensitivity-enhanced NMR spectroscopy. Journal of Biomolecular Nmr. 17: 79-82. PMID 10909868 DOI: 10.1023/A:1008373501591  0.8
2000 Shimotakahara S, Gorin A, Kolbanovskiy A, Kettani A, Hingerty BE, Amin S, Broyde S, Geacintov N, Patel DJ. Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove. Journal of Molecular Biology. 302: 377-93. PMID 10970740 DOI: 10.1006/jmbi.2000.4071  1
2000 Patel DJ, Suri AK. Structure, recognition and discrimination in RNA aptamer complexes with cofactors, amino acids, drugs and aminoglycoside antibiotics Journal of Biotechnology. 74: 39-60. PMID 10943571 DOI: 10.1016/S1389-0352(99)00003-3  1
2000 Kettani A, Basu G, Gorin A, Majumdar A, Skripkin E, Patel DJ. A two-stranded template-based approach to G·(C-A) triad formation: Designing novel structural elements into an existing DNA framework Journal of Molecular Biology. 301: 129-146. PMID 10926497 DOI: 10.1006/jmbi.2000.3932  1
2000 Hermann T, Patel DJ. RNA bulges as architectural and recognition motifs Structure. 8. PMID 10745015 DOI: 10.1016/S0969-2126(00)00110-6  1
2000 Kettani A, Gorin A, Majumdar A, Hermann T, Skripkin E, Zhao H, Jones R, Patel DJ. A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations. Journal of Molecular Biology. 297: 627-44. PMID 10731417 DOI: 10.1006/jmbi.2000.3524  0.8
2000 Majumdar A, Kettani A, Skripkin E, Patel DJ. Observation of internucleotide NH...N hydrogen bonds in the absence of directly detectable protons. Journal of Biomolecular Nmr. 15: 207-11. PMID 10677824 DOI: 10.1023/A:1008357304708  0.8
2000 Hermann T, Patel DJ. Adaptive recognition by nucleic acid aptamers Science. 287: 820-825. PMID 10657289 DOI: 10.1126/science.287.5454.820  1
2000 Jiang F, Gorin A, Hu W, Majumdar A, Baskerville S, Xu W, Ellington A, Patel DJ. Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples. Structure (London, England : 1993). 7: 1461-72. PMID 10647177 DOI: 10.1016/S0969-2126(00)88337-9  0.8
2000 Kuryavyi V, Kettani A, Wang W, Jones R, Patel DJ. A diamond-shaped zipper-like DNA architecture containing triads sandwiched between mismatches and tetrads. Journal of Molecular Biology. 295: 455-69. PMID 10623538 DOI: 10.1006/jmbi.1999.3345  0.4
2000 Liu A, Majumdar A, Hu W, Kettani A, Skripkin E, Patel DJ. NMR Detection of NH···OC Hydrogen Bonds in13C,15N-Labeled Nucleic Acids Journal of the American Chemical Society. 122: 3206-3210. DOI: 10.1021/ja994255s  0.8
2000 Liu A, Majumdar A, Jiang F, Chernichenko N, Skripkin E, Patel DJ. NMR Detection of Intermolecular N−H···N Hydrogen Bonds in the Human T Cell Leukemia Virus-1 Rex Peptide−RNA Aptamer Complex Journal of the American Chemical Society. 122: 11226-11227. DOI: 10.1021/ja003080f  0.8
1999 Hermann T, Patel DJ. Stitching together RNA tertiary architectures Journal of Molecular Biology. 294: 829-849. PMID 10588890 DOI: 10.1006/jmbi.1999.3312  1
1999 Gu Z, Gorin A, Hingerty BE, Broyde S, Patel DJ. Solution structures of aminofluorene [AF]-stacked conformers of the syn [AF]-C8-dG adduct positioned opposite dC or dA at a template-primer junction. Biochemistry. 38: 10855-70. PMID 10451382 DOI: 10.1021/bi991266p  1
1999 Gu Z, Gorin A, Krishnasamy R, Hingerty BE, Basu AK, Broyde S, Patel DJ. Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex. Biochemistry. 38: 10843-54. PMID 10451381 DOI: 10.1021/bi9912138  1
1999 Mao B, Gu Z, Gorin A, Chen J, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex. Biochemistry. 38: 10831-42. PMID 10451380 DOI: 10.1021/bi991212f  1
1999 Jiang L, Majumdar A, Hu W, Jaishree TJ, Xu W, Patel DJ. Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer. Structure (London, England : 1993). 7: 817-27. PMID 10425683 DOI: 10.1016/S0969-2126(99)80105-1  0.8
1999 Kettani A, Bouaziz S, Skripkin E, Majumdar A, Wang W, Jones RA, Patel DJ. Interlocked mismatch-aligned arrowhead DNA motifs. Structure (London, England : 1993). 7: 803-15. PMID 10425682 DOI: 10.1016/S0969-2126(99)80104-X  0.8
1999 Lin CH, Wang W, Jones RA, Patel DJ. Formation of an amino-acid-binding pocket through adaptive zippering-up of a large DNA hairpin loop. Chemistry & Biology. 5: 555-72. PMID 9818148 DOI: 10.1016/S1074-5521(98)90114-4  0.52
1999 Ye X, Gorin A, Frederick R, Hu W, Majumdar A, Xu W, McLendon G, Ellington A, Patel DJ. RNA architecture dictates the conformations of a bound peptide Chemistry and Biology. 6: 657-669. DOI: 10.1016/S1074-5521(99)80117-3  1
1998 Bouaziz S, Kettani A, Patel DJ. A K cation-induced conformational switch within a loop spanning segment of a DNA quadruplex containing G-G-G-C repeats. Journal of Molecular Biology. 282: 637-52. PMID 9737927 DOI: 10.1006/jmbi.1998.2031  0.4
1998 Kettani A, Bouaziz S, Gorin A, Zhao H, Jones RA, Patel DJ. Solution structure of a Na cation stabilized DNA quadruplex containing G.G.G.G and G.C.G.C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA. Journal of Molecular Biology. 282: 619-36. PMID 9737926 DOI: 10.1006/jmbi.1998.2030  0.52
1998 Patel DJ. Solution structure of the tobramycin-RNA aptamer complex Nature Structural Biology. 5: 769-774. PMID 9731769 DOI: 10.1038/1804  1
1998 Patel DJ, Mao B, Gu Z, Hingerty BE, Gorin A, Basu AK, Broyde S. Nuclear magnetic resonance solution structures of covalent aromatic amine-DNA adducts and their mutagenic relevance. Chemical Research in Toxicology. 11: 391-407. PMID 9585469 DOI: 10.1021/tx9702143  1
1998 Cai Z, Gorin A, Frederick R, Ye X, Hu W, Majumdar A, Kettani A, Patel DJ. Solution structure of P22 transcriptional antitermination N peptide-boxB RNA complex. Nature Structural Biology. 5: 203-12. PMID 9501914 DOI: 10.1038/nsb0398-203  0.8
1998 Mao B, Hingerty BE, Broyde S, Patel DJ. Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex. Biochemistry. 37: 95-106. PMID 9425029 DOI: 10.1021/bi972258g  1
1998 Mao B, Hingerty BE, Broyde S, Patel DJ. Solution structure of the aminofluorene [AF]-intercalated conformer of the syn-[AF]-C8-dG adduct opposite dC in a DNA duplex. Biochemistry. 37: 81-94. PMID 9425028 DOI: 10.1021/bi972257o  1
1998 Lin CH, Patel DJ. Structural basis of DNA folding and recognition in an AMP-DNA aptamer complex: distinct architectures but common recognition motifs for DNA and RNA aptamers complexed to AMP. Chemistry & Biology. 4: 817-32. PMID 9384529 DOI: 10.1016/S1074-5521(97)90115-0  0.36
1997 Mao B, Gu Z, Gorin A, Hingerty BE, Broyde S, Patel DJ. Solution structure of the aminofluorene-stacked conformer of the syn [AF]-C8-dG adduct positioned at a template-primer junction. Biochemistry. 36: 14491-501. PMID 9398168 DOI: 10.1021/bi972206r  1
1997 Mao B, Gorin A, Gu Z, Hingerty BE, Broyde S, Patel DJ. Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context. Biochemistry. 36: 14479-90. PMID 9398167 DOI: 10.1021/bi972205z  1
1997 Feng B, Gorin A, Kolbanovskiy A, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove. Biochemistry. 36: 13780-90. PMID 9374854 DOI: 10.1021/bi970070r  1
1997 Feng B, Gorin A, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction. Biochemistry. 36: 13769-79. PMID 9374853 DOI: 10.1021/bi970069s  1
1997 Patel DJ, Suri AK, Jiang F, Jiang L, Fan P, Kumar RA, Nonin S. Structure, recognition and adaptive binding in RNA aptamer complexes. Journal of Molecular Biology. 272: 645-64. PMID 9368648 DOI: 10.1006/jmbi.1997.1281  0.52
1997 Nonin S, Jiang F, Patel DJ. Imino proton exchange and base-pair kinetics in the AMP-RNA aptamer complex. Journal of Molecular Biology. 268: 359-74. PMID 9159476 DOI: 10.1006/jmbi.1997.0986  0.32
1997 Kettani A, Bouaziz S, Wang W, Jones RA, Patel DJ. Bombyx mori single repeat telomeric DNA sequence forms a G-quadruplex capped by base triads. Nature Structural Biology. 4: 382-9. PMID 9145109 DOI: 10.1038/nsb0597-382  0.52
1997 Jiang F, Patel DJ, Zhang X, Zhao H, Jones RA. Specific labeling approaches to guanine and adenine imino and amino proton assignments in the AMP-RNA aptamer complex. Journal of Biomolecular Nmr. 9: 55-62. PMID 9081544 DOI: 10.1023/A:1018623601946  0.52
1997 Jiang L, Suri AK, Fiala R, Patel DJ. Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex. Chemistry & Biology. 4: 35-50. PMID 9070426 DOI: 10.1016/S1074-5521(97)90235-0  0.52
1997 Geacintov NE, Cosman M, Hingerty BE, Amin S, Broyde S, Patel DJ. NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity. Chemical Research in Toxicology. 10: 111-46. PMID 9049424 DOI: 10.1021/tx9601418  1
1997 Lin CH, Patel DJ. Encapsulating an amino acid in a DNA fold. Nature Structural Biology. 3: 1046-50. PMID 8946859 DOI: 10.1038/nsb1296-1046  0.36
1997 Ye X, Gorin A, Ellington AD, Patel DJ. Deep penetration of an alpha-helix into a widened RNA major groove in the HIV-1 rev peptide-RNA aptamer complex. Nature Structural Biology. 3: 1026-33. PMID 8946856 DOI: 10.1038/nsb1296-1026  0.48
1996 Cullinan D, Korobka A, Grollman AP, Patel DJ, Eisenberg M, de los Santos C. NMR solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite thymidine: comparison with the duplex containing deoxyadenosine opposite the adduct. Biochemistry. 35: 13319-27. PMID 8873598 DOI: 10.1021/bi9605705  1
1996 Korobka A, Cullinan D, Cosman M, Grollman AP, Patel DJ, Eisenberg M, de los Santos C. Solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite 2'-deoxyadenosine, determined by NMR spectroscopy and restrained molecular dynamics. Biochemistry. 35: 13310-8. PMID 8873597 DOI: 10.1021/bi9605696  1
1996 Jiang F, Fiala R, Live D, Kumar RA, Patel DJ. RNA folding topology and intermolecular contacts in the AMP-RNA aptamer complex. Biochemistry. 35: 13250-66. PMID 8855964 DOI: 10.1021/bi961345q  0.44
1996 Mao B, Vyas RR, Hingerty BE, Broyde S, Basu AK, Patel DJ. Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex. Biochemistry. 35: 12659-70. PMID 8841109 DOI: 10.1021/bi961078o  1
1996 Greenbaum NL, Radhakrishnan I, Patel DJ, Hirsh D. Solution structure of the donor site of a trans-splicing RNA. Structure (London, England : 1993). 4: 725-33. PMID 8805553 DOI: 10.1016/S0969-2126(96)00078-0  1
1996 Cosman M, Hingerty BE, Luneva N, Amin S, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove. Biochemistry. 35: 9850-63. PMID 8703959 DOI: 10.1021/bi9605346  1
1996 Fan P, Suri AK, Fiala R, Live D, Patel DJ. Molecular recognition in the FMN-RNA aptamer complex. Journal of Molecular Biology. 258: 480-500. PMID 8642604 DOI: 10.1006/jmbi.1996.0263  0.44
1996 Chen H, Liu X, Patel DJ. DNA bending and unwinding associated with actinomycin D antibiotics bound to partially overlapping sites on DNA. Journal of Molecular Biology. 258: 457-79. PMID 8642603 DOI: 10.1006/jmbi.1996.0262  1
1996 Kettani A, Kumar RA, Patel DJ. Solution structure of a DNA quadruplex containing the fragile X syndrome triplet repeat. Journal of Molecular Biology. 254: 638-56. PMID 7500339 DOI: 10.1006/jmbi.1995.0644  0.4
1996 Fiala R, Jiang F, Patel DJ. Direct Correlation of Exchangeable and Nonexchangeable Protons on Purine Bases in13C,15N-Labeled RNA Using a HCCNH-TOCSY Experiment Journal of the American Chemical Society. 118: 689-690. DOI: 10.1021/ja9533656  0.32
1996 Chen H, Johnson F, Grollman AP, Patel DJ. Structural Studies of the Ionizing Radiation Adduct 7,8-Dihydro-8-oxoadenine (Aoxo) Positioned Opposite Thymine in a DNA Duplex Magnetic Resonance in Chemistry. 34: S23-S32. DOI: 10.1002/(SICI)1097-458X(199612)34:133.0.CO;2-V  1
1995 Mao B, Hingerty BE, Broyde S, Patel DJ. Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified syn guanine and adjacent unpaired 3'-adenine into the major groove. Biochemistry. 34: 16641-53. PMID 8527437 DOI: 10.1021/bi00051a012  1
1995 Patel DJ, Gumbiner BM. Zipping together a cell adhesion interface Nature. 374: 306-307. PMID 7885464 DOI: 10.1038/374306a0  1
1995 Chen H, Patel DJ. Solution structure of a quinomycin bisintercalator-DNA complex. Journal of Molecular Biology. 246: 164-79. PMID 7853395 DOI: 10.1006/jmbi.1994.0074  1
1995 Lin CH, Patel DJ. Solution structure of the covalent duocarmycin A-DNA duplex complex. Journal of Molecular Biology. 248: 162-79. PMID 7731041 DOI: 10.1006/jmbi.1995.0209  0.36
1995 Wang Y, Patel DJ. Bulge defects in intramolecular pyrimidine.purine.pyrimidine DNA triplexes in solution. Biochemistry. 34: 5696-704. PMID 7727429 DOI: 10.1021/bi00016a046  0.52
1995 Wang Y, Patel DJ. Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex. Structure (London, England : 1993). 2: 1141-56. PMID 7704525 DOI: 10.1016/S0969-2126(94)00117-0  0.52
1995 Wang Y, Patel DJ. Solution structure of the Oxytricha telomeric repeat d[G4(T4G4)3] G-tetraplex. Journal of Molecular Biology. 251: 76-94. PMID 7643391 DOI: 10.1006/jmbi.1995.0417  0.52
1995 Cosman M, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction. Biochemistry. 34: 15334-50. PMID 7578150 DOI: 10.1021/bi00046a043  1
1995 Greenbaum NL, Radhakrishnan I, Hirsh D, Patel DJ. Determination of the folding topology of the SL1 RNA from Caenorhabditis elegans by multidimensional heteronuclear NMR. Journal of Molecular Biology. 252: 314-27. PMID 7563053 DOI: 10.1006/jmbi.1995.0499  1
1995 Chen H, Patel DJ. Solution Structure of the Menogaril-DNA Complex Journal of the American Chemical Society. 117: 5901-5913. DOI: 10.1021/ja00127a001  1
1994 Wang Y, Patel DJ. Solution structure of a parallel-stranded G-quadruplex DNA. Journal of Molecular Biology. 234: 1171-83. PMID 8263919 DOI: 10.1006/jmbi.1993.1668  0.52
1994 Patel DJ. A clasped embrace Nature. 369: 438-439. PMID 8202130 DOI: 10.1038/369438a0  1
1994 Patel DJ. A molecular handshake Nature. 367: 688-690. PMID 8107862 DOI: 10.1038/367688a0  1
1994 Radhakrishnan I, Patel DJ. Hydration sites in purine.purine.pyrimidine and pyrimidine.purine.pyrimidine DNA triplexes in aqueous solution. Structure (London, England : 1993). 2: 395-405. PMID 8081755 DOI: 10.1016/S0969-2126(00)00041-1  1
1994 Wang Y, Patel DJ. Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex. Structure (London, England : 1993). 1: 263-82. PMID 8081740 DOI: 10.1016/0969-2126(93)90015-9  0.52
1994 Radhakrishnan I, Patel DJ. Solution structure of a pyrimidine.purine.pyrimidine DNA triplex containing T.AT, C+.GC and G.TA triples. Structure (London, England : 1993). 2: 17-32. PMID 8075980 DOI: 10.1016/S0969-2126(00)00005-8  1
1994 Radhakrishnan I, Patel DJ. Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples. Structure (London, England : 1993). 1: 135-52. PMID 8069626 DOI: 10.1016/0969-2126(93)90028-F  1
1994 Radhakrishnan I, Patel DJ. Solution structure and hydration patterns of a pyrimidine.purine.pyrimidine DNA triplex containing a novel T.CG base-triple. Journal of Molecular Biology. 241: 600-19. PMID 8057381 DOI: 10.1006/jmbi.1994.1534  1
1994 Radhakrishnan I, Patel DJ. DNA triplexes: solution structures, hydration sites, energetics, interactions, and function. Biochemistry. 33: 11405-16. PMID 7522550 DOI: 10.1021/bi00204a001  1
1994 Ikemoto N, Kumar RA, Dedon PC, Danishefsky SJ, Patel DJ. Esperamicin A1 intercalates into duplex DNA from the minor groove Journal of the American Chemical Society. 116: 9387-9388. DOI: 10.1021/ja00099a089  1
1994 Wang Y, Patel DJ. Solution Stucture of the d(T-C-G-A) Duplex at Acidic pH Journal of Molecular Biology. 242: 508-526. DOI: 10.1006/jmbi.1994.1770  0.52
1993 Patel DJ. Tetrads through interdigitation Nature. 363: 499-500. PMID 8505977 DOI: 10.1038/363499a0  1
1993 Cosman M, de los Santos C, Fiala R, Hingerty BE, Ibanez V, Luna E, Harvey R, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine. Biochemistry. 32: 4145-55. PMID 8476845 DOI: 10.1021/bi00067a001  1
1993 Patel DJ. Marriage of convenience Nature. 365: 490-492. PMID 8413600 DOI: 10.1038/365490a0  1
1993 Rosen MA, Patel DJ. Structural features of a three-stranded DNA junction containing a C-C junctional bulge Biochemistry. 32: 6576-6587. PMID 8329386 DOI: 10.1021/bi00077a011  1
1993 Rosen MA, Patel DJ. Conformational differences between bulged pyrimidines (C-C) and purines (A-A, I-I) at the branch point of three-stranded DNA junctions Biochemistry. 32: 6563-6575. PMID 8329385 DOI: 10.1021/bi00077a010  1
1993 Cosman M, Fiala R, Hingerty BE, Laryea A, Lee H, Harvey RG, Amin S, Geacintov NE, Broyde S, Patel D. Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair. Biochemistry. 32: 12488-97. PMID 8241140 DOI: 10.1021/bi00097a029  1
1993 Radhakrishnan I, de los Santos C, Patel DJ. Nuclear magnetic resonance structural studies of A.AT base triple alignments in intramolecular purine.purine.pyrimidine DNA triplexes in solution. Journal of Molecular Biology. 234: 188-97. PMID 8230198 DOI: 10.1006/jmbi.1993.1573  1
1993 Radhakrishnan I, Patel DJ, Priestly ES, Nash HM, Dervan PB. NMR structural studies on a nonnatural deoxyribonucleoside which mediates recognition of GC base pairs in pyrimidine-purine-pyrimidine DNA triplexes. Biochemistry. 32: 11228-34. PMID 8218188 DOI: 10.1021/bi00092a037  1
1993 Ye X, Kimura KI, Patel DJ. Site-specific intercalation of an anthracycline antitumor antibiotic into a Y·RY DNA triplex through covalent adduct formation Journal of the American Chemical Society. 115: 9325-9326. DOI: 10.1021/ja00073a073  1
1993 Radhakrishnan I, Patel DJ. Solution/structure of an intramolecular purine-purine-pyrimidine DNA triplex Journal of the American Chemical Society. 115: 1615-1617. DOI: 10.1021/ja00057a078  1
1992 Liu X, Chen H, Patel DJ. Solution structure of actinomycin-DNA complexes: drug intercalation at isolated G-C sites. Journal of Biomolecular Nmr. 1: 323-47. PMID 1841703 DOI: 10.1007/BF02192858  1
1992 Gao XL, Mirau P, Patel DJ. Structure refinement of the chromomycin dimer-DNA oligomer complex in solution. Journal of Molecular Biology. 223: 259-79. PMID 1731073 DOI: 10.1016/0022-2836(92)90730-8  0.92
1992 de los Santos C, Cosman M, Hingerty BE, Ibanez V, Margulis LA, Geacintov NE, Broyde S, Patel DJ. Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer. Biochemistry. 31: 5245-52. PMID 1606148 DOI: 10.1021/bi00138a002  1
1992 Radhakrishnan I, Patel DJ, Gao X. Three-dimensional homonuclear NOESY-TOCSY of an intramolecular pyrimidine.purine.pyrimidine DNA triplex containing a central G.TA triple: nonexchangeable proton assignments and structural implications. Biochemistry. 31: 2514-23. PMID 1547235 DOI: 10.1021/bi00124a011  1
1992 Wang Y, Patel DJ. Guanine residues in d(T2AG3) and d(T2G4) form parallel-stranded potassium cation stabilized G-quadruplexes with anti glycosidic torsion angles in solution. Biochemistry. 31: 8112-9. PMID 1525153 DOI: 10.1021/bi00150a002  0.52
1992 Gopalakrishnan S, Liu X, Patel DJ. Solution structure of the covalent sterigmatocystin-DNA adduct Biochemistry. 31: 10790-10801. PMID 1329956 DOI: 10.1021/bi00159a021  1
1992 Rosen MA, Shapiro L, Patel DJ. Solution structure of a trinucleotide A-T-A bulge loop within a DNA duplex. Biochemistry. 31: 4015-26. PMID 1314655 DOI: 10.1021/bi00131a017  0.52
1992 Rosen MA, Live D, Patel DJ. Comparative NMR study of An-bulge loops in DNA duplexes: Intrahelical stacking of A, A-A, and A-A-A bulge loops Biochemistry. 31: 4004-4014. PMID 1314654 DOI: 10.1021/bi00131a016  1
1992 Leroy JL, Gao XL, Misra V, Guéron M, Patel DJ. Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening. Biochemistry. 31: 1407-15. PMID 1310611 DOI: 10.1021/bi00120a017  1
1992 Lin CH, Patel DJ. Site-specific covalent duocarmycin A: intramolecular DNA triplex complex Journal of the American Chemical Society. 114: 10658-10660. DOI: 10.1021/ja00052a085  0.36
1992 Radhakrishnan I, Patel DJ, Veal JM, Gao X. Solution conformation of a G.cntdot.TA [guanosine.cntdot.thymidine-5'-adenylic acid] triple in an intramolecular pyrimidine.cntdot.purine.cntdot.pyrimidine DNA triplex Journal of the American Chemical Society. 114: 6913-6915. DOI: 10.1021/ja00043a045  1
1992 Patel DJ. Covalent carcinogenic guanine-modified DNA lesions: solution structures of adducts and crosslinks Current Opinion in Structural Biology. 2: 345-353. DOI: 10.1016/0959-440X(92)90224-U  1
1991 Zhang XL, Patel DJ. Solution structure of the nogalamycin-DNA complex. Biochemistry. 29: 9451-66. PMID 2174261 DOI: 10.1021/bi00492a020  0.36
1991 Kouchakdjian M, Eisenberg M, Johnson F, Grollman AP, Patel DJ. Structural features of an exocyclic adduct positioned opposite an abasic site in a DNA duplex. Biochemistry. 30: 3262-70. PMID 2009264 DOI: 10.1021/bi00227a014  0.36
1991 Patel DJ. NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (εdA) opposite deoxyguanosine in a DNA duplex. εdA(syn)·dG(anti) pairing at the lesion site Biochemistry. 30: 1828-1835. PMID 1993197 DOI: 10.1021/bi00221a015  1
1991 Patel DJ. NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (εda) opposite thymidine in a DNA duplex. Nonplanar alignment of εdA(anti) and dT(anti) at the lesion site Biochemistry. 30: 1820-1828. PMID 1993196 DOI: 10.1021/bi00221a014  1
1991 Kouchakdjian M, Bodepudi V, Shibutani S, Eisenberg M, Johnson F, Grollman AP, Patel DJ. NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn)·dA(anti) alignment at lesion site Biochemistry. 30: 1403-1412. PMID 1991121 DOI: 10.1021/bi00219a034  1
1991 Ashcroft J, Live DH, Patel DJ, Cowburn D. Heteronuclear two-dimensional 15N- and 13C-NMR studies of DNA oligomers and their netropsin complexes using indirect proton detection. Biopolymers. 31: 45-55. PMID 1851045 DOI: 10.1002/bip.360310105  0.36
1991 Zhang XL, Patel DJ. Solution structure of the luzopeptin-DNA complex. Biochemistry. 30: 4026-41. PMID 1850297 DOI: 10.1021/bi00230a030  0.36
1991 Wang Y, de los Santos C, Gao XO, Greene K, Live D, Patel DJ. Multinuclear nuclear magnetic resonance studies of Na cation-stabilized complex formed by d(G-G-T-T-T-T-C-G-G) in solution. Implications for G-tetrad structures. Journal of Molecular Biology. 222: 819-32. PMID 1660934 DOI: 10.1016/0022-2836(91)90513-6  0.52
1991 Radhakrishnan I, Gao X, de los Santos C, Live D, Patel DJ. NMR structural studies of intramolecular (Y+)n.(R+)n(Y-)nDNA triplexes in solution: imino and amino proton and nitrogen markers of G.TA base triple formation. Biochemistry. 30: 9022-30. PMID 1654085 DOI: 10.1021/bi00101a016  1
1991 Leroy JL, Gao XL, Guéron M, Patel DJ. Proton exchange and internal motions in two chromomycin dimer-DNA oligomer complexes. Biochemistry. 30: 5653-61. PMID 1645996 DOI: 10.1021/bi00237a003  1
1991 Radhakrishnan I, Patel D, Gao X. NMR assignment strategy for DNA protons through three-dimensional proton-proton connectivities. Application to an intramolecular DNA triplex Journal of the American Chemical Society. 113: 8542-8544. DOI: 10.1021/ja00022a063  1
1991 Live DH, Radhakrishnan I, Misra V, Patel DJ. Characterization of protonated cytidine in oligonucleotides by nitrogen-15 NMR studies at natural abundance Journal of the American Chemical Society. 113: 4687-4688. DOI: 10.1021/ja00012a051  1
1991 Radhakrishnan I, de los Santos C, Patel DJ. Nuclear magnetic resonance structural studies of intramolecular purine · purine · pyrimidine DNA triplexes in solution Journal of Molecular Biology. 221: 1403-1418. DOI: 10.1016/0022-2836(91)90941-X  1
1990 de los Santos C, Rosen M, Patel D. NMR studies of DNA (R+)n.(Y-)n.(Y+)n triple helices in solution: imino and amino proton markers of T.A.T and C.G.C+ base-triple formation. Biochemistry. 28: 7282-9. PMID 2819069 DOI: 10.1021/bi00444a021  0.56
1990 Norman D, Live D, Sastry M, Lipman R, Hingerty BE, Tomasz M, Broyde S, Patel DJ. NMR and computational characterization of mitomycin cross-linked to adjacent deoxyguanosines in the minor groove of the d(T-A-C-G-T-A).d(T-A-C-G-T-A) duplex. Biochemistry. 29: 2861-75. PMID 2346750 DOI: 10.1021/bi00463a032  1
1990 Gao XL, Patel DJ. Chromomycin dimer-DNA oligomer complexes. Sequence selectivity and divalent cation specificity. Biochemistry. 29: 10940-56. PMID 2176890 DOI: 10.1021/bi00501a012  0.92
1990 Kouchakdjian M, Eisenberg M, Live D, Marinelli E, Grollman AP, Patel DJ. NMR studies of an exocyclic 1,N2-propanodeoxyguanosine adduct (X) located opposite deoxyadenosine (A) in DNA duplexes at basic pH: simultaneous partial intercalation of X and A between stacked bases. Biochemistry. 29: 4456-65. PMID 2161685 DOI: 10.1021/bi00470a028  0.44
1989 Norman D, Abuaf P, Hingerty BE, Live D, Grunberger D, Broyde S, Patel DJ. NMR and computational characterization of the N-(deoxyguanosin-8-yl)aminofluorene adduct [(AF)G] opposite adenosine in DNA: (AF)G[syn].A[anti] pair formation and its pH dependence. Biochemistry. 28: 7462-76. PMID 2819081 DOI: 10.1021/bi00444a046  1
1989 Kouchakdjian M, Marinelli E, Gao XL, Johnson F, Grollman A, Patel D. NMR studies of exocyclic 1,N2-propanodeoxyguanosine adducts (X) opposite purines in DNA duplexes: protonated X(syn).A(anti) pairing (acidic pH) and X(syn).G(anti) pairing (neutral pH) at the lesion site. Biochemistry. 28: 5647-57. PMID 2775729 DOI: 10.1021/bi00439a047  0.92
1989 Gao XL, Patel DJ. Solution structure of the chromomycin-DNA complex. Biochemistry. 28: 751-62. PMID 2713341 DOI: 10.1021/bi00428a051  0.92
1989 Kalnik MW, Norman DG, Zagorski MG, Swann PF, Patel DJ. Conformational transitions in cytidine bulge-containing deoxytridecanucleotide duplexes: extra cytidine equilibrates between looped out (low temperature) and stacked (elevated temperature) conformations in solution. Biochemistry. 28: 294-303. PMID 2706253 DOI: 10.1021/bi00427a040  1
1989 Gao XL, Patel DJ. Antitumour drug-DNA interactions: NMR studies of echinomycin and chromomycin complexes. Quarterly Reviews of Biophysics. 22: 93-138. PMID 2675172 DOI: 10.1017/S0033583500003814  0.92
1989 Zagorski MG, Bowie JU, Vershon AK, Sauer RT, Patel DJ. NMR studies of Arc repressor mutants: proton assignments, secondary structure, and long-range contacts for the thermostable proline-8----leucine variant of Arc. Biochemistry. 28: 9813-25. PMID 2611267 DOI: 10.1021/bi00451a041  1
1989 Kalnik MW, Chang CN, Johnson F, Grollman AP, Patel DJ. NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite acyclic lesions. Biochemistry. 28: 3373-83. PMID 2545258 DOI: 10.1021/bi00434a037  0.36
1989 Hosur RV, Majumdar A, Patel DJ. Measurement of proton-proton coupling constants in oligonucleotides by 2D NMR: application of .omega.1-decoupling Journal of the American Chemical Society. 111: 5482-5483. DOI: 10.1021/ja00196a074  0.8
1988 Gao XL, Patel DJ. NMR studies of echinomycin bisintercalation complexes with d(A1-C2-G3-T4) and d(T1-C2-G3-A4) duplexes in aqueous solution: sequence-dependent formation of Hoogsteen A1.T4 and Watson--Crick T1.A4 base pairs flanking the bisintercalation site. Biochemistry. 27: 1744-51. PMID 3365421 DOI: 10.1021/bi00405a054  0.92
1988 Kalnik MW, Chang CN, Grollman AP, Patel DJ. NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite the cyclic analogue of 2-deoxyribose. Biochemistry. 27: 924-31. PMID 3259144 DOI: 10.1021/bi00403a013  0.36
1988 Patel DJ, Shapiro L, Hare D. DNA and RNA: NMR studies of conformations and dynamics in solution. Quarterly Reviews of Biophysics. 20: 35-112. PMID 2448843 DOI: 10.1017/s0033583500004224  0.52
1988 Gao X, Patel DJ. G(syn).cntdot.A(anti) mismatch formation in DNA dodecamers at acidic pH: pH-dependent conformational transition of G.cntdot.A mispairs detected by proton NMR Journal of the American Chemical Society. 110: 5178-5182. DOI: 10.1021/ja00223a045  0.96
1987 Hare D, Shapiro L, Patel DJ. Extrahelical adenosine stacks into right-handed DNA: solution conformation of the d(C-G-C-A-G-A-G-C-T-C-G-C-G) duplex deduced from distance geometry analysis of nuclear Overhauser effect spectra. Biochemistry. 25: 7456-64. PMID 3801425 DOI: 10.1021/bi00371a030  0.52
1987 Hare D, Shapiro L, Patel DJ. Wobble dG X dT pairing in right-handed DNA: solution conformation of the d(C-G-T-G-A-A-T-T-C-G-C-G) duplex deduced from distance geometry analysis of nuclear Overhauser effect spectra. Biochemistry. 25: 7445-56. PMID 3801424 DOI: 10.1021/bi00371a029  0.52
1987 Gao XL, Patel DJ. NMR studies of A.C mismatches in DNA dodecanucleotides at acidic pH. Wobble A(anti).C(anti) pair formation. The Journal of Biological Chemistry. 262: 16973-84. PMID 3680285  0.92
1987 Patel DJ, Shapiro L, Hare D. Nuclear magnetic resonance and distance geometry studies of DNA structures in solution. Annual Review of Biophysics and Biophysical Chemistry. 16: 423-54. PMID 3036173 DOI: 10.1146/annurev.bb.16.060187.002231  0.52
1986 Patel DJ, Shapiro L, Kozlowski SA, Gaffney BL, Kuzmich S, Jones RA. Covalent carcinogenic lesions in DNA: NMR studies of O6-methylguanosine containing oligonucleotide duplexes. Biochimie. 67: 861-86. PMID 4084607 DOI: 10.1016/S0300-9084(85)80180-2  0.52
1986 Patel DJ, Shapiro L, Kozlowski SA, Gaffney BL, Jones RA. Structural studies of the O6meG.C interaction in the d(C-G-C-G-A-A-T-T-C-O6meG-C-G) duplex. Biochemistry. 25: 1027-36. PMID 3964658 DOI: 10.1021/bi00353a012  0.52
1986 Patel DJ, Shapiro L, Hare D. Sequence-dependent conformations of DNA duplexes: the TATA segment of the d(G-G-T-A-T-A-C-C) duplex in aqueous solution. Biopolymers. 25: 693-706. PMID 3708110 DOI: 10.1002/bip.360250412  0.52
1986 Patel DJ, Shapiro L, Kozlowski SA, Gaffney BL, Jones RA. Covalent carcinogenic O6-methylguanosine lesions in DNA. Structural studies of the O6 meG X A and O6meG X G interactions in dodecanucleotide duplexes. Journal of Molecular Biology. 188: 677-92. PMID 3016288 DOI: 10.1016/S0022-2836(86)80014-6  0.52
1986 Patel DJ, Shapiro L. Sequence-dependent recognition of DNA duplexes: netropsin complexation to the TATA site of the d(G-G-T-A-T-A-C-C) duplex in aqueous solution. Biopolymers. 25: 707-27. PMID 3011140 DOI: 10.1002/bip.360250413  0.52
1986 Patel DJ, Shapiro L. Molecular recognition in noncovalent antitumor agent-DNA complexes: NMR studies of the base and sequence dependent recognition of the DNA minor groove by netropsin. Biochimie. 67: 887-915. PMID 3002497 DOI: 10.1016/S0300-9084(85)80181-4  0.52
1985 Patel DJ, Kozlowski SA, Weiss M, Bhatt R. Conformation and dynamics of the Pribnow box region of the self-complementary d(C-G-A-T-T-A-T-A-A-T-C-G) duplex in solution. Biochemistry. 24: 936-44. PMID 3995000 DOI: 10.1021/bi00325a019  0.52
1985 Patel DJ, Kozlowski SA, Hare DR, Reid B, Ikuta S, Lander N, Itakura K. Conformation, dynamics, and structural transitions of the TATA box region of self-complementary d[(C-G)n-T-A-T-A-(C-G)n] duplexes in solution. Biochemistry. 24: 926-35. PMID 3994999 DOI: 10.1021/bi00325a018  1
1984 Möller A, Nordheim A, Kozlowski SA, Patel DJ, Rich A. Bromination stabilizes poly(dG-dC) in the Z-DNA form under low-salt conditions. Biochemistry. 23: 54-62. PMID 6691966 DOI: 10.1021/bi00296a009  0.52
1984 Patel DJ, Kozlowski SA, Ikuta S, Itakura K. Deoxyguanosine-deoxyadenosine pairing in the d(C-G-A-G-A-A-T-T-C-G-C-G) duplex: conformation and dynamics at and adjacent to the dG X dA mismatch site. Biochemistry. 23: 3207-17. PMID 6466638 DOI: 10.1021/bi00309a015  0.52
1984 Patel DJ, Kozlowski SA, Ikuta S, Itakura K. Deoxyadenosine-deoxycytidine pairing in the d(C-G-C-G-A-A-T-T-C-A-C-G) duplex: conformation and dynamics at and adjacent to the dA X dC mismatch site. Biochemistry. 23: 3218-26. PMID 6331846 DOI: 10.1021/bi00309a016  0.52
1983 Patel DJ, Kozlowski SA, Bhatt R. Sequence dependence of base-pair stacking in right-handed DNA in solution: proton nuclear Overhauser effect NMR measurements. Proceedings of the National Academy of Sciences of the United States of America. 80: 3908-12. PMID 6575384 DOI: 10.1073/pnas.80.13.3908  0.52
1983 Patel DJ, Kozlowski SA, Ikuta S, Itakura K, Bhatt R, Hare DR. NMR studies of DNA conformation and dynamics in solution. Cold Spring Harbor Symposia On Quantitative Biology. 47: 197-206. PMID 6574840 DOI: 10.1101/SQB.1983.047.01.025  1
1983 Patel DJ, Ikuta S, Kozlowski S, Itakura K. Sequence dependence of hydrogen exchange kinetics in DNA duplexes at the individual base pair level in solution Proceedings of the National Academy of Sciences of the United States of America. 80: 2184-2188. PMID 6572970 DOI: 10.1073/pnas.80.8.2184  1
1983 Pardi A, Morden KM, Patel DJ, Tinoco I. Kinetics for exchange of the imino protons of the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix in complexes with the antibiotics netropsin and/or actinomycin. Biochemistry. 22: 1107-13. PMID 6301539 DOI: 10.1021/bi00274a018  1
1982 Patel DJ, Kozlowski SA, Marky LA, Rice JA, Broka C, Itakura K, Breslauer KJ. Structure and energetics of a hexanucleotide duplex with stacked trinucleotide ends formed by the sequence d(GAATTCGCG). Biochemistry. 21: 451-5. PMID 7066297 DOI: 10.1021/bi00532a005  1
1982 Patel DJ, Kozlowski SA, Marky LA, Rice JA, Broka C, Itakura K, Breslauer KJ. Extra adenosine stacks into the self-complementary d(CGCAGAATTCGCG) duplex in solution. Biochemistry. 21: 445-51. PMID 7066296 DOI: 10.1021/bi00532a004  1
1982 Patel DJ, Kozlowski SA, Marky LA, Rice JA, Broka C, Dallas J, Itakura K, Breslauer KJ. Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution. Biochemistry. 21: 437-44. PMID 7066295 DOI: 10.1021/bi00532a003  1
1982 Patel DJ, Kozlowski SA, Marky LA, Broka C, Rice JA, Itakura K, Breslauer KJ. Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution. Biochemistry. 21: 428-36. PMID 7066294 DOI: 10.1021/bi00532a002  1
1982 Patel DJ, Kozlowski SA. Right-handed and left-handed DNA: Studies of B- and Z-DNA by using proton nuclear Overhauser effect and P NMR Proceedings of the National Academy of Sciences of the United States of America. 79: 1413-1417. PMID 6951185 DOI: 10.1073/pnas.79.5.1413  1
1982 Pardi A, Morden KM, Patel DJ, Tinoco I. Kinetics for exchange of imino protons in the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix and in two similar helices that contain a G . T base pair, d(C-G-T-G-A-A-T-T-C-G-C-G), and an extra adenine, d(C-G-C-A-G-A-A-T-T-C-G-C-G). Biochemistry. 21: 6567-74. PMID 6295469 DOI: 10.1021/bi00268a038  1
1982 Patel DJ. Antibiotic-DNA interactions: Intermolecular nuclear Overhauser effects in the netropsin-d(C-G-C-G-A-A-T-T-C-G-C-G) complex in solution Proceedings of the National Academy of Sciences of the United States of America. 79: 6424-6428. PMID 6292900 DOI: 10.1073/pnas.79.21.6424  1
1982 Patel DJ, Pardi A, Itakura K. DNA conformation, dynamics, and interactions in solution Science. 216: 581-590. PMID 6280281 DOI: 10.1126/science.6280281  1
1981 Patel DJ, Kozlowski SA, Suggs JW, Cox SD. Right-handed alternating DNA conformation: poly(dA-dT) adopts the same dinucleotide repeat with cesium, tetraalkylammonium, and 3 alpha, 5 beta, 17 beta-dipyrrolidinium steroid dimethiodide cations in aqueous solution. Proceedings of the National Academy of Sciences of the United States of America. 78: 4063-7. PMID 6945570 DOI: 10.1073/pnas.78.7.4063  1
1981 Patel DJ, Kozlowski SA, Rice JA, Broka C, Itakura K. Mutual interaction between adjacent dG . dC actinomycin binding sites and dA . dT netropsin binding sites on the self-complementary d(C-G-C-G-A-A-T-T-C-G-C-G) duplex in solution. Proceedings of the National Academy of Sciences of the United States of America. 78: 7281-4. PMID 6278465 DOI: 10.1073/pnas.78.12.7281  0.52
1981 Patel DJ, Kozlowski SA, Rice JA. Hydrogen bonding, overlap geometry, and sequence specificity in anthracycline antitumor antibiotic.DNA complexes in solution. Proceedings of the National Academy of Sciences of the United States of America. 78: 3333-7. PMID 6267584 DOI: 10.1073/pnas.78.6.3333  0.52
1980 Chen DM, Sakai TT, Glickson JD, Patel DJ. Bleomycin-A2 complexes with poly(dA-dT): A proton nuclear magnetic resonance study of the nonexchangeable hydrogens Biochemical and Biophysical Research Communications. 92: 197-205. PMID 6153523 DOI: 10.1016/0006-291X(80)91539-9  1
1979 Patel DJ. Netropsin . dG-dG-dA-dA-dT-dT-dC-dC complex. Antibiotic binding at adenine . tymine base pairs in the minor groove of the self-complementary octanucleotide duplex octanucleotide duplux European Journal of Biochemistry. 99: 369-378. PMID 499206 DOI: 10.1111/j.1432-1033.1979.tb13265.x  1
1979 Patel DJ. Helix-coil transition of the dG-dC-dG-dC self-complementary duplex and complex formation with daunomycin in solution Biopolymers. 18: 553-569. PMID 444634 DOI: 10.1002/bip.1979.360180307  1
1978 Patel DJ. Synthetic RNA and DNA duplexes. Premelting, melting and postmelting transitions of alternating inosine-cytosine polynucleotides in solution European Journal of Biochemistry. 83: 453-464. PMID 631128 DOI: 10.1111/j.1432-1033.1978.tb12111.x  1
1978 Patel DJ, Shen C. Sugar pucker geometries at the intercalation site of propidium diiodide into miniature RNA and DNA duplexes in solution. Proceedings of the National Academy of Sciences of the United States of America. 75: 2553-7. PMID 275825 DOI: 10.1073/pnas.75.6.2553  0.36
1977 Shen C, Patel DJ. Free acid, anion, alkali, and alkaline earth complexes of lasalocid a (X537A) in methanol: structural and kinetic studies at the monomer level. Proceedings of the National Academy of Sciences of the United States of America. 73: 4277-81. PMID 1069983 DOI: 10.1073/pnas.73.12.4277  0.36
1977 Patel DJ. d-CpCpGpG and d-GpGpCpC self complementary duplexes: Nmr studies of the helix coil transition Biopolymers. 16: 1635-1656. PMID 890063 DOI: 10.1002/bip.1977.360160804  1
1977 Patel DJ. Mutagen-nucleic acid complexes at the polynucleotide duplex level in solution: intercalation of proflavine into poly(dA-dT) and the melting transition of the complex Biopolymers. 16: 2739-2754. PMID 597577 DOI: 10.1002/bip.1977.360161212  1
1976 Patel DJ. Proton and phosphorus NMR studies of d CpG(pCpG)n duplexes in solution. Helix coil transition and complex formation with actinomycin D Biopolymers. 15: 533-558. PMID 1252592 DOI: 10.1002/bip.1976.360150310  1
1976 Nakanishi K, Yudd AP, Crouch RK, Olson GL, Cheung HC, Govindjee R, Ebrey TG, Patel DJ. Letter: Allenic retinals and visual pigment analogues. Journal of the American Chemical Society. 98: 236-8. PMID 1244368 DOI: 10.1021/ja00417a040  1
1976 Patel DJ, Shen C. Structural and kinetic studies of lasalocid A (X537A) and its silver, sodium, and barium salts in nonpolar solvents. Proceedings of the National Academy of Sciences of the United States of America. 73: 1786-90. PMID 1064852 DOI: 10.1073/pnas.73.6.1786  0.36
1976 Patel DJ, Canuel L. Nuclear magnetic resonance studies of the helix-coil transition of poly (dA-dT) in aqueous solution. Proceedings of the National Academy of Sciences of the United States of America. 73: 674-8. PMID 1062778 DOI: 10.1073/pnas.73.3.674  0.36
1976 Patel DJ. NMR studies of the structure and stability of the 1 : 2 actinomycin D · d-pG-C complex in aqueous solution Bba Section Nucleic Acids and Protein Synthesis. 442: 98-108. PMID 953004 DOI: 10.1016/0005-2787(76)90180-5  1
1975 Patel DJ, Canuel LL, Bovey FA. Reassignment of the active site histidines in ribonuclease A by selective deuteration studies. Biopolymers. 14: 987-97. PMID 1156653 DOI: 10.1002/bip.1975.360140508  1
1975 Patel DJ. The predicted secondary structure of the N-terminal sequence of the lac repressor and proposed models for its complexation to the lac operator Biochemistry. 14: 1057-1059. PMID 1092326 DOI: 10.1021/bi00676a027  1
1975 Patel DJ, Canuel LL, Bovey FA, Woodward C. Assignment of the imidazole ring nitrogen protons of histidine 48 in the proton NMR spectrum of ribonuclease A in water solution. Biochimica Et Biophysica Acta. 400: 275-82. PMID 240416 DOI: 10.1016/0005-2795(75)90182-8  1
1975 Patel DJ, Woodward C, Canuel LL, Bovey FA. Correlation of exchangeable (NH) and nonexchangeable (C2H) histidine resonances in the proton NMR spectrum of ribonuclease A in aqueous solution. Biopolymers. 14: 975-86. PMID 239769 DOI: 10.1002/bip.1975.360140507  1
1975 Patel DJ, Canuel LL, Woodward C, Bovey FA. Assignment of the histidine 12-threonine 45 hydrogen-bonded proton in the NMR spectrum of ribonuclease A in H2O. Biopolymers. 14: 959-74. PMID 239768 DOI: 10.1002/bip.1975.360140506  1
1975 Hilbers CW, Patel DJ. Proton nuclear magnetic resonance investigations of the nucleation and propagation reactions associated with the helix-coil transition of d-ApTpGpCpApT in H2O solution Biochemistry. 14: 2656-2660. PMID 238569 DOI: 10.1021/bi00683a015  1
1975 Patel DJ, Hilbers CW. Proton nuclear magnetic resonance investigations of fraying in double-stranded d-ApTpGpCpApT in H2O solution Biochemistry. 14: 2651-2656. PMID 238568 DOI: 10.1021/bi00683a014  1
1975 SERVIS KL, PATEL DJ. ChemInform Abstract: ASPECTS OF THE VALINOMYCIN BACKBONE CONFORMATION IN CHLOROFORM SOLUTION USING LANTHANIDE SHIFT REAGENTS. EVALUATION OF PHI (D-VAL) AND PSI (D-HYIV) ROTATION ANGLES Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197536079  0.32
1974 Patel DJ. Peptide antibiotic-dinucleotide interactions. Nuclear magnetic resonance investigations of complex formation between actinomycin D and d-pGpG in aqueous solution Biochemistry. 13: 2388-2395. PMID 4831638 DOI: 10.1021/bi00708a024  1
1974 Ogawa S, Patel DJ, Simon SR. Proton magnetic resonance study of the switch between the two quaternary structures in high-affinity hemoglobins in the deoxy state Biochemistry. 13: 2001-2006. PMID 4826881 DOI: 10.1021/bi00707a001  1
1974 Patel DJ. Peptide antibiotic-nucleotide interactions. Nuclear magnetic resonance investigations of complex formation between actinomycin D and deoxyguanosine 5′-monophosphate in aqueous solution Biochemistry. 13: 1476-1482. PMID 4819760 DOI: 10.1021/bi00704a025  1
1973 Patel DJ. Conformation of antamanide-sodium in solution Biochemistry. 12: 677-688. PMID 4691512 DOI: 10.1021/bi00728a017  1
1973 Patel DJ. Antamanide conformations in nonaqueous media. Dependence on hydrogen-bond acceptor properties of solvent Biochemistry. 12: 667-676. PMID 4691511 DOI: 10.1021/bi00728a016  1
1973 Patel DJ. Carbon framework of valinomycin and its metal ion complex in solution Biochemistry. 12: 496-501. PMID 4683492 DOI: 10.1021/bi00727a021  1
1972 Patel DJ, Woodward CK, Bovey FA. Proton nuclear magnetic resonance studies of ribonuclease A in H 2 O. Proceedings of the National Academy of Sciences of the United States of America. 69: 599-602. PMID 4501576 DOI: 10.1073/pnas.69.3.599  1
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