Peter B. Dervan - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 
Area:
DNA recognition
Website:
http://dervan.caltech.edu/dervan.html

244 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kurmis AA, Dervan PB. Sequence specific suppression of androgen receptor-DNA binding in vivo by a Py-Im polyamide. Nucleic Acids Research. PMID 30838415 DOI: 10.1093/nar/gkz153  0.76
2018 Diaz-Perez S, Kane N, Kurmis AA, Yang F, Kummer NT, Dervan PB, Nickols NG. Interference with DNA repair after ionizing radiation by a pyrrole-imidazole polyamide. Plos One. 13: e0196803. PMID 29715291 DOI: 10.1371/journal.pone.0196803  0.92
2017 Xu J, Lahiri I, Wang W, Wier A, Cianfrocco MA, Chong J, Hare AA, Dervan PB, DiMaio F, Leschziner AE, Wang D. Structural basis for the initiation of eukaryotic transcription-coupled DNA repair. Nature. PMID 29168508 DOI: 10.1038/nature24658  0.6
2017 Kurmis AA, Yang F, Welch TR, Nickols NG, Dervan PB. A pyrrole-imidazole polyamide is active against enzalutamide-resistant prostate cancer. Cancer Research. PMID 28360139 DOI: 10.1158/0008-5472.CAN-16-2503  0.92
2016 Xu L, Wang W, Gotte D, Yang F, Hare AA, Welch TR, Li BC, Shin JH, Chong J, Strathern JN, Dervan PB, Wang D. RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791148 DOI: 10.1073/pnas.1612745113  0.92
2016 Gerhardt J, Bhalla AD, Butler JS, Puckett JW, Dervan PB, Rosenwaks Z, Napierala M. Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells. Cell Reports. PMID 27425605 DOI: 10.1016/j.celrep.2016.06.075  0.88
2015 Szablowski JO, Raskatov JA, Dervan PB. An HRE-binding Py-Im polyamide impairs hypoxic signaling in tumors. Molecular Cancer Therapeutics. PMID 26719577 DOI: 10.1158/1535-7163.MCT-15-0719  1
2015 Hargrove AE, Martinez TF, Hare AA, Kurmis AA, Phillips JW, Sud S, Pienta KJ, Dervan PB. Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide. Plos One. 10: e0143161. PMID 26571387 DOI: 10.1371/journal.pone.0143161  1
2015 Kang JS, Dervan PB. A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma. Quarterly Reviews of Biophysics. 48: 453-64. PMID 26537405 DOI: 10.1017/S0033583515000104  1
2014 Martínez TF, Phillips JW, Karanja KK, Polaczek P, Wang CM, Li BC, Campbell JL, Dervan PB. Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response. Nucleic Acids Research. 42: 11546-59. PMID 25249630 DOI: 10.1093/nar/gku866  1
2014 Raskatov JA, Szablowski JO, Dervan PB. Tumor xenograft uptake of a pyrrole-imidazole (Py-Im) polyamide varies as a function of cell line grafted. Journal of Medicinal Chemistry. 57: 8471-6. PMID 25238175 DOI: 10.1021/jm500964c  1
2014 Raskatov JA, Puckett JW, Dervan PB. A C-14 labeled Py-Im polyamide localizes to a subcutaneous prostate cancer tumor. Bioorganic & Medicinal Chemistry. 22: 4371-5. PMID 24780272 DOI: 10.1016/j.bmc.2014.04.010  1
2014 Kang JS, Meier JL, Dervan PB. Design of sequence-specific DNA binding molecules for DNA methyltransferase inhibition. Journal of the American Chemical Society. 136: 3687-94. PMID 24502234 DOI: 10.1021/ja500211z  1
2013 Yang F, Nickols NG, Li BC, Szablowski JO, Hamilton SR, Meier JL, Wang CM, Dervan PB. Animal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit. Journal of Medicinal Chemistry. 56: 7449-57. PMID 24015881 DOI: 10.1021/jm401100s  1
2013 Nickols NG, Szablowski JO, Hargrove AE, Li BC, Raskatov JA, Dervan PB. Activity of a Py-Im polyamide targeted to the estrogen response element. Molecular Cancer Therapeutics. 12: 675-84. PMID 23443804 DOI: 10.1158/1535-7163.MCT-12-1040  1
2013 Edwards JS, Betts L, Frazier ML, Pollet RM, Kwong SM, Walton WG, Ballentine WK, Huang JJ, Habibi S, Del Campo M, Meier JL, Dervan PB, Firth N, Redinbo MR. Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 110: 2804-9. PMID 23359708 DOI: 10.1073/pnas.1219701110  1
2013 Yang F, Nickols NG, Li BC, Marinov GK, Said JW, Dervan PB. Antitumor activity of a pyrrole-imidazole polyamide. Proceedings of the National Academy of Sciences of the United States of America. 110: 1863-8. PMID 23319609 DOI: 10.1073/pnas.1222035110  1
2013 Li BC, Montgomery DC, Puckett JW, Dervan PB. Synthesis of cyclic Py-Im polyamide libraries. The Journal of Organic Chemistry. 78: 124-33. PMID 23106218 DOI: 10.1021/jo302053v  0.92
2013 Chenoweth DM, Meier JL, Dervan PB. Pyrrole-imidazole polyamides distinguish between double-helical DNA and RNA. Angewandte Chemie (International Ed. in English). 52: 415-8. PMID 22987334 DOI: 10.1002/anie.201205775  1
2012 Meier JL, Yu AS, Korf I, Segal DJ, Dervan PB. Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing. Journal of the American Chemical Society. 134: 17814-22. PMID 23013524 DOI: 10.1021/ja308888c  1
2012 Raskatov JA, Nickols NG, Hargrove AE, Marinov GK, Wold B, Dervan PB. Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide. Proceedings of the National Academy of Sciences of the United States of America. 109: 16041-5. PMID 22988074 DOI: 10.1073/pnas.1214267109  1
2012 Synold TW, Xi B, Wu J, Yen Y, Li BC, Yang F, Phillips JW, Nickols NG, Dervan PB. Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice. Cancer Chemotherapy and Pharmacology. 70: 617-25. PMID 22907527 DOI: 10.1007/s00280-012-1954-3  1
2012 Du J, Campau E, Soragni E, Ku S, Puckett JW, Dervan PB, Gottesfeld JM. Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells. The Journal of Biological Chemistry. 287: 29861-72. PMID 22798143 DOI: 10.1074/jbc.M112.391961  1
2012 Jespersen C, Soragni E, James Chou C, Arora PS, Dervan PB, Gottesfeld JM. Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells. Bioorganic & Medicinal Chemistry Letters. 22: 4068-71. PMID 22607671 DOI: 10.1016/j.bmcl.2012.04.090  1
2012 Hargrove AE, Raskatov JA, Meier JL, Montgomery DC, Dervan PB. Characterization and solubilization of pyrrole-imidazole polyamide aggregates. Journal of Medicinal Chemistry. 55: 5425-32. PMID 22607187 DOI: 10.1021/jm300380a  1
2012 Puckett JW, Green JT, Dervan PB. Microwave assisted synthesis of Py-Im polyamides. Organic Letters. 14: 2774-7. PMID 22578091 DOI: 10.1021/ol3010003  1
2012 Raskatov JA, Hargrove AE, So AY, Dervan PB. Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear. Journal of the American Chemical Society. 134: 7995-9. PMID 22509786 DOI: 10.1021/ja302588v  1
2012 Raskatov JA, Meier JL, Puckett JW, Yang F, Ramakrishnan P, Dervan PB. Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders. Proceedings of the National Academy of Sciences of the United States of America. 109: 1023-8. PMID 22203967 DOI: 10.1073/pnas.1118506109  1
2012 Meier JL, Montgomery DC, Dervan PB. Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns. Nucleic Acids Research. 40: 2345-56. PMID 22080545 DOI: 10.1093/nar/gkr970  1
2011 Zhang Y, Sicot G, Cui X, Vogel M, Wuertzer CA, Lezon-Geyda K, Wheeler J, Harki DA, Muzikar KA, Stolper DA, Dervan PB, Perkins AS. Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide. Biochemistry. 50: 10431-41. PMID 22039883 DOI: 10.1021/bi200962u  1
2011 Muzikar KA, Meier JL, Gubler DA, Raskatov JA, Dervan PB. Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA. Organic Letters. 13: 5612-5. PMID 21957930 DOI: 10.1021/ol202285y  1
2010 Chenoweth DM, Dervan PB. Structural basis for cyclic Py-Im polyamide allosteric inhibition of nuclear receptor binding. Journal of the American Chemical Society. 132: 14521-9. PMID 20812704 DOI: 10.1021/ja105068b  1
2009 Muzikar KA, Nickols NG, Dervan PB. Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression. Proceedings of the National Academy of Sciences of the United States of America. 106: 16598-603. PMID 19805343 DOI: 10.1073/pnas.0909192106  1
2009 Chenoweth DM, Dervan PB. Allosteric modulation of DNA by small molecules. Proceedings of the National Academy of Sciences of the United States of America. 106: 13175-9. PMID 19666554 DOI: 10.1073/pnas.0906532106  1
2009 Chenoweth DM, Harki DA, Dervan PB. Oligomerization route to Py-Im polyamide macrocycles. Organic Letters. 11: 3590-3. PMID 19627138 DOI: 10.1021/ol901311m  1
2009 Jacobs CS, Dervan PB. Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture. Journal of Medicinal Chemistry. 52: 7380-8. PMID 19572551 DOI: 10.1021/jm900256f  1
2009 Ho D, Dose C, Albrecht CH, Severin P, Falter K, Dervan PB, Gaub HE. Quantitative detection of small molecule/DNA complexes employing a force-based and label-free DNA-microarray. Biophysical Journal. 96: 4661-71. PMID 19486688 DOI: 10.1016/j.bpj.2009.02.059  1
2009 Chenoweth DM, Harki DA, Dervan PB. Solution-phase synthesis of pyrrole-imidazole polyamides. Journal of the American Chemical Society. 131: 7175-81. PMID 19413320 DOI: 10.1021/ja901307m  1
2009 Chenoweth DM, Harki DA, Phillips JW, Dose C, Dervan PB. Cyclic pyrrole-imidazole polyamides targeted to the androgen response element. Journal of the American Chemical Society. 131: 7182-8. PMID 19413319 DOI: 10.1021/ja901309z  1
2009 Farkas ME, Li BC, Dose C, Dervan PB. DNA sequence selectivity of hairpin polyamide turn units. Bioorganic & Medicinal Chemistry Letters. 19: 3919-23. PMID 19349175 DOI: 10.1016/j.bmcl.2009.03.072  1
2008 Harki DA, Satyamurthy N, Stout DB, Phelps ME, Dervan PB. In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 105: 13039-44. PMID 18753620 DOI: 10.1073/pnas.0806308105  1
2008 Hsu CF, Dervan PB. Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cells. Bioorganic & Medicinal Chemistry Letters. 18: 5851-5. PMID 18524590 DOI: 10.1016/j.bmcl.2008.05.063  1
2008 Dose C, Farkas ME, Chenoweth DM, Dervan PB. Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit. Journal of the American Chemical Society. 130: 6859-66. PMID 18459783 DOI: 10.1021/ja800888d  1
2008 Moretti R, Donato LJ, Brezinski ML, Stafford RL, Hoff H, Thorson JS, Dervan PB, Ansari AZ. Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly. Acs Chemical Biology. 3: 220-9. PMID 18422304 DOI: 10.1021/cb700258r  1
2008 Chou CJ, Farkas ME, Tsai SM, Alvarez D, Dervan PB, Gottesfeld JM. Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia. Molecular Cancer Therapeutics. 7: 769-78. PMID 18413791 DOI: 10.1158/1535-7163.MCT-08-0130  1
2008 Cohen JD, Sadowski JP, Dervan PB. Programming multiple protein patterns on a single DNA nanostructure. Journal of the American Chemical Society. 130: 402-3. PMID 18081289 DOI: 10.1021/ja0772400  1
2007 Hsu CF, Phillips JW, Trauger JW, Farkas ME, Belitsky JM, Heckel A, Olenyuk BZ, Puckett JW, Wang CC, Dervan PB. Completion of a Programmable DNA-Binding Small Molecule Library. Tetrahedron. 63: 6146-6151. PMID 18596841 DOI: 10.1016/j.tet.2007.03.041  1
2007 Stafford RL, Dervan PB. The reach of linear protein-DNA dimerizers. Journal of the American Chemical Society. 129: 14026-33. PMID 17949089 DOI: 10.1021/ja075247b  1
2007 Dose C, Ho D, Gaub HE, Dervan PB, Albrecht CH. Recognition of "mirror-image" DNA by small molecules. Angewandte Chemie (International Ed. in English). 46: 8384-7. PMID 17899583 DOI: 10.1002/anie.200703007  1
2007 Puckett JW, Muzikar KA, Tietjen J, Warren CL, Ansari AZ, Dervan PB. Quantitative microarray profiling of DNA-binding molecules. Journal of the American Chemical Society. 129: 12310-9. PMID 17880081 DOI: 10.1021/ja0744899  1
2007 Farkas ME, Tsai SM, Dervan PB. Alpha-diaminobutyric acid-linked hairpin polyamides. Bioorganic & Medicinal Chemistry. 15: 6927-36. PMID 17869122 DOI: 10.1016/j.bmc.2007.07.019  1
2007 Cohen JD, Sadowski JP, Dervan PB. Addressing single molecules on DNA nanostructures. Angewandte Chemie (International Ed. in English). 46: 7956-9. PMID 17763481 DOI: 10.1002/anie.200702767  1
2007 Nickols NG, Jacobs CS, Farkas ME, Dervan PB. Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface. Acs Chemical Biology. 2: 561-71. PMID 17708671 DOI: 10.1021/cb700110z  1
2007 Nickols NG, Dervan PB. Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide. Proceedings of the National Academy of Sciences of the United States of America. 104: 10418-23. PMID 17566103 DOI: 10.1073/pnas.0704217104  1
2007 Stafford RL, Arndt HD, Brezinski ML, Ansari AZ, Dervan PB. Minimization of a protein-DNA dimerizer. Journal of the American Chemical Society. 129: 2660-8. PMID 17290996 DOI: 10.1021/ja067971k  1
2007 Chenoweth DM, Viger A, Dervan PB. Fluorescent sequence-specific dsDNA binding oligomers. Journal of the American Chemical Society. 129: 2216-7. PMID 17279754 DOI: 10.1021/ja0682576  1
2007 Nickols NG, Jacobs CS, Farkas ME, Dervan PB. Improved nuclear localization of DNA-binding polyamides. Nucleic Acids Research. 35: 363-70. PMID 17175539 DOI: 10.1093/nar/gkl1042  1
2007 Tsai SM, Farkas ME, Chou CJ, Gottesfeld JM, Dervan PB. Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates. Nucleic Acids Research. 35: 307-16. PMID 17170006 DOI: 10.1093/nar/gkl1025  1
2007 Chenoweth DM, Poposki JA, Marques MA, Dervan PB. Programmable oligomers targeting 5'-GGGG-3' in the minor groove of DNA and NF-kappaB binding inhibition. Bioorganic & Medicinal Chemistry. 15: 759-70. PMID 17095230 DOI: 10.1016/j.bmc.2006.10.051  1
2007 Dervan PB, Urbach AR. The Importance of β-Alanine for Recognition of the Minor Groove of DNA Essays in Contemporary Chemistry: From Molecular Structure Towards Biology. 327-339. DOI: 10.1002/9783906390451.ch9  1
2006 Viger A, Dervan PB. Exploring the limits of benzimidazole DNA-binding oligomers for the hypoxia inducible factor (HIF) site. Bioorganic & Medicinal Chemistry. 14: 8539-49. PMID 16971129 DOI: 10.1016/j.bmc.2006.08.028  1
2006 Alvarez D, Chou CJ, Latella L, Zeitlin SG, Ku S, Puri PL, Dervan PB, Gottesfeld JM. A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate. Cell Cycle (Georgetown, Tex.). 5: 1537-48. PMID 16861886  1
2006 Burnett R, Melander C, Puckett JW, Son LS, Wells RD, Dervan PB, Gottesfeld JM. DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia. Proceedings of the National Academy of Sciences of the United States of America. 103: 11497-502. PMID 16857735 DOI: 10.1073/pnas.0604939103  1
2006 Doss RM, Marques MA, Foister S, Chenoweth DM, Dervan PB. Programmable oligomers for minor groove DNA recognition. Journal of the American Chemical Society. 128: 9074-9. PMID 16834381 DOI: 10.1021/ja0621795  1
2006 Warren CL, Kratochvil NC, Hauschild KE, Foister S, Brezinski ML, Dervan PB, Phillips GN, Ansari AZ. Defining the sequence-recognition profile of DNA-binding molecules. Proceedings of the National Academy of Sciences of the United States of America. 103: 867-72. PMID 16418267 DOI: 10.1073/pnas.0509843102  1
2006 Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting Cancer Proliferation by Small-Molecule Gene Regulation (DOI:10.1016/j.chembiol.2004.09.004) Chemistry and Biology. 13: 339. DOI: 10.1016/j.chembiol.2006.02.006  1
2005 Fechter EJ, Olenyuk B, Dervan PB. Sequence-specific fluorescence detection of DNA by polyamide-thiazole orange conjugates. Journal of the American Chemical Society. 127: 16685-91. PMID 16305259 DOI: 10.1021/ja054650k  1
2005 Dervan PB, Doss RM, Marques MA. Programmable DNA binding oligomers for control of transcription. Current Medicinal Chemistry. Anti-Cancer Agents. 5: 373-87. PMID 16101489 DOI: 10.2174/1568011054222346  1
2005 Hauschild KE, Metzler RE, Arndt HD, Moretti R, Raffaelle M, Dervan PB, Ansari AZ. Temperature-sensitive protein-DNA dimerizers. Proceedings of the National Academy of Sciences of the United States of America. 102: 5008-13. PMID 15781856 DOI: 10.1073/pnas.0501289102  1
2005 Gearhart MD, Dickinson L, Ehley J, Melander C, Dervan PB, Wright PE, Gottesfeld JM. Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides. Biochemistry. 44: 4196-203. PMID 15766247 DOI: 10.1021/bi047872o  1
2005 Philips BJ, Chang AY, Dervan PB, Beerman TA. DNA damage effects of a polyamide-CBI conjugate in SV40 virions. Molecular Pharmacology. 67: 877-82. PMID 15576630 DOI: 10.1124/mol.104.006254  1
2005 Edayathumangalam RS, Weyermann P, Dervan PB, Gottesfeld JM, Luger K. Nucleosomes in solution exist as a mixture of twist-defect states. Journal of Molecular Biology. 345: 103-14. PMID 15567414 DOI: 10.1016/j.jmb.2004.10.012  1
2005 Dervan PB, Poulin-Kerstien AT, Fechter EJ, Edelson BS. Regulation of gene expression by synthetic DNA-binding ligands Topics in Current Chemistry. 253: 1-31. DOI: 10.1007/b100440  1
2004 Doss RM, Marques MA, Foister S, Dervan PB. DNA minor-groove recognition by 3-methylthiophene/pyrrole pair. Chemistry & Biodiversity. 1: 886-99. PMID 17191889 DOI: 10.1002/cbdv.200490071  1
2004 Kwon Y, Arndt HD, Mao Q, Choi Y, Kawazoe Y, Dervan PB, Uesugi M. Small molecule transcription factor mimic. Journal of the American Chemical Society. 126: 15940-1. PMID 15584709 DOI: 10.1021/ja0445140  1
2004 Olenyuk BZ, Zhang GJ, Klco JM, Nickols NG, Kaelin WG, Dervan PB. Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist. Proceedings of the National Academy of Sciences of the United States of America. 101: 16768-73. PMID 15556999 DOI: 10.1073/pnas.0407617101  1
2004 Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting cancer proliferation by small-molecule gene regulation. Chemistry & Biology. 11: 1583-94. PMID 15556009 DOI: 10.1016/j.chembiol.2004.09.004  1
2004 Ylisastigui L, Coull JJ, Rucker VC, Melander C, Bosch RJ, Brodie SJ, Corey L, Sodora DL, Dervan PB, Margolis DM. Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors. The Journal of Infectious Diseases. 190: 1429-37. PMID 15378435 DOI: 10.1086/423822  1
2004 Livengood JA, Fechter EJ, Dervan PB, Nyborg JK. Paradoxical effects of DNA binding polyamides on HTLV-1 transcription. Frontiers in Bioscience : a Journal and Virtual Library. 9: 3058-67. PMID 15353337  1
2004 Marques MA, Doss RM, Foister S, Dervan PB. Expanding the repertoire of heterocycle ring pairs for programmable minor groove DNA recognition. Journal of the American Chemical Society. 126: 10339-49. PMID 15315448 DOI: 10.1021/ja0486465  1
2004 Fechter EJ, Olenyuk B, Dervan PB. Design of a sequence-specific DNA bisintercalator. Angewandte Chemie (International Ed. in English). 43: 3591-4. PMID 15293255 DOI: 10.1002/anie.200454231  1
2004 Zhang Q, Dwyer TJ, Tsui V, Case DA, Cho J, Dervan PB, Wemmer DE. NMR structure of a cyclic polyamide-DNA complex. Journal of the American Chemical Society. 126: 7958-66. PMID 15212545 DOI: 10.1021/ja0373622  1
2004 Edelson BS, Best TP, Olenyuk B, Nickols NG, Doss RM, Foister S, Heckel A, Dervan PB. Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates. Nucleic Acids Research. 32: 2802-18. PMID 15155849 DOI: 10.1093/nar/gkh609  1
2004 Edayathumangalam RS, Weyermann P, Gottesfeld JM, Dervan PB, Luger K. Molecular recognition of the nucleosomal "supergroove". Proceedings of the National Academy of Sciences of the United States of America. 101: 6864-9. PMID 15100411 DOI: 10.1073/pnas.0401743101  0.72
2004 Nguyen-Hackley DH, Ramm E, Taylor CM, Joung JK, Dervan PB, Pabo CO. Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands. Biochemistry. 43: 3880-90. PMID 15049695 DOI: 10.1021/bi030223c  1
2004 Rucker VC, Dunn AR, Sharma S, Dervan PB, Gray HB. Mechanism of sequence-specific fluorescent detection of DNA by N-methyl-imidazole, N-methyl-pyrrole, and β-alanine linked polyamides Journal of Physical Chemistry B. 108: 7490-7494. DOI: 10.1021/jp037423i  1
2003 Poulin-Kerstien AT, Dervan PB. DNA-templated dimerization of hairpin polyamides. Journal of the American Chemical Society. 125: 15811-21. PMID 14677972 DOI: 10.1021/ja030494a  1
2003 Arndt HD, Hauschild KE, Sullivan DP, Lake K, Dervan PB, Ansari AZ. Toward artificial developmental regulators. Journal of the American Chemical Society. 125: 13322-3. PMID 14583004 DOI: 10.1021/ja0371395  1
2003 Dudouet B, Burnett R, Dickinson LA, Wood MR, Melander C, Belitsky JM, Edelson B, Wurtz N, Briehn C, Dervan PB, Gottesfeld JM. Accessibility of nuclear chromatin by DNA binding polyamides. Chemistry & Biology. 10: 859-67. PMID 14522056 DOI: 10.1016/j.chembiol.2003.09.001  1
2003 Best TP, Edelson BS, Nickols NG, Dervan PB. Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 100: 12063-8. PMID 14519850 DOI: 10.1073/pnas.2035074100  1
2003 Foister S, Marques MA, Doss RM, Dervan PB. Shape selective recognition of T.A base pairs by hairpin polyamides containing N-terminal 3-methoxy (and 3-chloro) thiophene residues. Bioorganic & Medicinal Chemistry. 11: 4333-40. PMID 13129569 DOI: 10.1016/S0968-0896(03)00502-9  1
2003 Heckel A, Dervan PB. U-pin polyamide motif for recognition of the DNA minor groove. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 3353-66. PMID 12866079 DOI: 10.1002/chem.200304784  1
2003 Fechter EJ, Dervan PB. Allosteric inhibition of protein--DNA complexes by polyamide--intercalator conjugates. Journal of the American Chemical Society. 125: 8476-85. PMID 12848553 DOI: 10.1021/ja030125e  1
2003 Dervan PB, Edelson BS. Recognition of the DNA minor groove by pyrrole-imidazole polyamides. Current Opinion in Structural Biology. 13: 284-99. PMID 12831879 DOI: 10.1016/S0959-440X(03)00081-2  1
2003 Yang F, Belitsky JM, Villanueva RA, Dervan PB, Roth MJ. Inhibition of Moloney murine leukemia virus integration using polyamides targeting the long-terminal repeat sequences. Biochemistry. 42: 6249-58. PMID 12755629 DOI: 10.1021/bi034177s  1
2003 Briehn CA, Weyermann P, Dervan PB. Alternative heterocycles for DNA recognition: the benzimidazole/imidazole pair. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 2110-22. PMID 12740860 DOI: 10.1002/chem.200204689  1
2003 Renneberg D, Dervan PB. Imidazopyridine/Pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition. Journal of the American Chemical Society. 125: 5707-16. PMID 12733909 DOI: 10.1021/ja0300158  1
2003 Olenyuk B, Jitianu C, Dervan PB. Parallel synthesis of H-pin polyamides by alkene metathesis on solid phase. Journal of the American Chemical Society. 125: 4741-51. PMID 12696892 DOI: 10.1021/ja0213221  1
2003 Wang YD, Dziegielewski J, Wurtz NR, Dziegielewska B, Dervan PB, Beerman TA. DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate. Nucleic Acids Research. 31: 1208-15. PMID 12582240 DOI: 10.1093/nar/gkg215  1
2003 Suto RK, Edayathumangalam RS, White CL, Melander C, Gottesfeld JM, Dervan PB, Luger K. Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. Journal of Molecular Biology. 326: 371-80. PMID 12559907 DOI: 10.1016/S0022-2836(02)01407-9  1
2003 Rucker VC, Foister S, Melander C, Dervan PB. Sequence specific fluorescence detection of double strand DNA. Journal of the American Chemical Society. 125: 1195-202. PMID 12553822 DOI: 10.1021/ja021011q  1
2003 Rucker VC, Melander C, Dervan PB. Influence of β-alanine on hairpin polyamide orientation in the DNA minor groove Helvetica Chimica Acta. 86: 1839-1851. DOI: 10.1002/hlca.200390148  1
2002 Coull JJ, He G, Melander C, Rucker VC, Dervan PB, Margolis DM. Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrrole-imidazole polyamides. Journal of Virology. 76: 12349-54. PMID 12414976 DOI: 10.1128/JVI.76.23.12349-12354.2002  1
2002 Arora PS, Ansari AZ, Best TP, Ptashne M, Dervan PB. Design of artificial transcriptional activators with rigid poly-L-proline linkers. Journal of the American Chemical Society. 124: 13067-71. PMID 12405833 DOI: 10.1021/ja0208355  1
2002 Hawkins CA, Baird EE, Dervan PB, Wemmer DE. Analysis of hairpin polyamide complexes having DNA binding sites in close proximity. Journal of the American Chemical Society. 124: 12689-96. PMID 12392416 DOI: 10.1021/ja020335b  1
2002 Wang YD, Dziegielewski J, Chang AY, Dervan PB, Beerman TA. Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate. The Journal of Biological Chemistry. 277: 42431-7. PMID 12196541 DOI: 10.1074/jbc.M207179200  1
2002 Kers I, Dervan PB. Search for the optimal linker in tandem hairpin polyamides. Bioorganic & Medicinal Chemistry. 10: 3339-49. PMID 12150881 DOI: 10.1016/S0968-0896(02)00221-3  1
2002 Belitsky JM, Leslie SJ, Arora PS, Beerman TA, Dervan PB. Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates. Bioorganic & Medicinal Chemistry. 10: 3313-8. PMID 12150878 DOI: 10.1016/S0968-0896(02)00204-3  1
2002 Gottesfeld JM, Belitsky JM, Melander C, Dervan PB, Luger K. Blocking transcription through a nucleosome with synthetic DNA ligands. Journal of Molecular Biology. 321: 249-63. PMID 12144782 DOI: 10.1016/S0022-2836(02)00598-3  1
2002 Urbach AR, Love JJ, Ross SA, Dervan PB. Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif. Journal of Molecular Biology. 320: 55-71. PMID 12079334 DOI: 10.1016/S0022-2836(02)00430-8  1
2002 Weyermann P, Dervan PB. Recognition of ten base pairs of DNA by head-to-head hairpin dimers. Journal of the American Chemical Society. 124: 6872-8. PMID 12059208 DOI: 10.1021/ja020258k  1
2002 Belitsky JM, Nguyen DH, Wurtz NR, Dervan PB. Solid-phase synthesis of DNA binding polyamides on oxime resin. Bioorganic & Medicinal Chemistry. 10: 2767-74. PMID 12057666 DOI: 10.1016/S0968-0896(02)00133-5  1
2002 Wurtz NR, Pomerantz JL, Baltimore D, Dervan PB. Inhibition of DNA binding by NF-kappa B with pyrrole-imidazole polyamides. Biochemistry. 41: 7604-9. PMID 12056891 DOI: 10.1021/bi020114i  1
2002 Ehley JA, Melander C, Herman D, Baird EE, Ferguson HA, Goodrich JA, Dervan PB, Gottesfeld JM. Promoter scanning for transcription inhibition with DNA-binding polyamides. Molecular and Cellular Biology. 22: 1723-33. PMID 11865052 DOI: 10.1128/MCB.22.6.1723-1733.2002  1
2002 Marques MA, Doss RM, Urbach AR, Dervan PB. Toward an understanding of the chemical etiology for DNA minor-groove recognition by polyamides Helvetica Chimica Acta. 85: 4485-4517. DOI: 10.1002/hlca.200290024  1
2001 Dervan PB. Molecular recognition of DNA by small molecules. Bioorganic & Medicinal Chemistry. 9: 2215-35. PMID 11553460 DOI: 10.1016/S0968-0896(01)00262-0  1
2001 Wang CC, Dervan PB. Sequence-specific trapping of topoisomerase I by DNA binding polyamide-camptothecin conjugates. Journal of the American Chemical Society. 123: 8657-61. PMID 11535069 DOI: 10.1021/ja010392p  1
2001 Bremer RE, Wurtz NR, Szewczyk JW, Dervan PB. Inhibition of major groove DNA binding bZIP proteins by positive patch polyamides. Bioorganic & Medicinal Chemistry. 9: 2093-103. PMID 11504645 DOI: 10.1016/S0968-0896(01)00122-5  1
2001 Trauger JW, Dervan PB. Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes. Methods in Enzymology. 340: 450-66. PMID 11494863 DOI: 10.1016/S0076-6879(01)40436-8  1
2001 Ansari AZ, Mapp AK, Nguyen DH, Dervan PB, Ptashne M. Towards a minimal motif for artificial transcriptional activators. Chemistry & Biology. 8: 583-92. PMID 11410377 DOI: 10.1016/S1074-5521(01)00037-0  1
2001 Gottesfeld JM, Melander C, Suto RK, Raviol H, Luger K, Dervan PB. Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides. Journal of Molecular Biology. 309: 615-29. PMID 11397084 DOI: 10.1006/jmbi.2001.4694  1
2001 Wurtz NR, Turner JM, Baird EE, Dervan PB. Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids. Organic Letters. 3: 1201-3. PMID 11348194 DOI: 10.1021/ol0156796  1
2001 Wang CC, Ellervik U, Dervan PB. Expanding the recognition of the minor groove of DNA by incorporation of beta-alanine in hairpin polyamides. Bioorganic & Medicinal Chemistry. 9: 653-7. PMID 11310600 DOI: 10.1016/S0968-0896(00)00282-0  1
2001 Urbach AR, Dervan PB. Toward rules for 1:1 polyamide:DNA recognition. Proceedings of the National Academy of Sciences of the United States of America. 98: 4343-8. PMID 11296283 DOI: 10.1073/pnas.081070798  1
2001 Nguyen DH, Szewczyk JW, Baird EE, Dervan PB. Alternative heterocycles for DNA recognition: an N-methylpyrazole/N-methylpyrrole pair specifies for A.T/T.A base pairs. Bioorganic & Medicinal Chemistry. 9: 7-17. PMID 11197348 DOI: 10.1016/S0968-0896(00)00219-4  1
2001 Baliga R, Baird EE, Herman DM, Melander C, Dervan PB, Crothers DM. Kinetic consequences of covalent linkage of DNA binding polyamides. Biochemistry. 40: 3-8. PMID 11141050 DOI: 10.1021/bi0022339  1
2000 Melander C, Herman DM, Dervan PB. Discrimination of A/T sequences in the minor groove of DNA within a cyclic polyamide motif. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 4487-97. PMID 11192081 DOI: 10.1002/1521-3765(20001215)6:24<4487::AID-CHEM4487>3.0.CO;2-C  1
2000 Gottesfeld JM, Turner JM, Dervan PB. Chemical approaches to control gene expression. Gene Expression. 9: 77-91. PMID 11097426  1
2000 Zhan ZY, Dervan PB. Alternative heterocycles for DNA recognition: a 3-pyrazole/pyrrole pair specifies for G.C base pairs. Bioorganic & Medicinal Chemistry. 8: 2467-74. PMID 11058042 DOI: 10.1016/S0968-0896(00)00182-6  1
2000 Bremer RE, Szewczyk JW, Baird EE, Dervan PB. Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl- and N-methylpyrrole. Bioorganic & Medicinal Chemistry. 8: 1947-55. PMID 11003140 DOI: 10.1016/S0968-0896(00)00145-0  1
2000 Winston RL, Ehley JA, Baird EE, Dervan PB, Gottesfeld JM. Asymmetric DNA binding by a homodimeric bHLH protein. Biochemistry. 39: 9092-8. PMID 10924102 DOI: 10.1021/bi000947d  1
2000 Chiang SY, Burli RW, Benz CC, Gawron L, Scott GK, Dervan PB, Beerman TA. Targeting the ets binding site of the HER2/neu promoter with pyrrole-imidazole polyamides. The Journal of Biological Chemistry. 275: 24246-54. PMID 10818092 DOI: 10.1074/jbc.M000820200  1
2000 Mapp AK, Ansari AZ, Ptashne M, Dervan PB. Activation of gene expression by small molecule transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 97: 3930-5. PMID 10760265 DOI: 10.1073/pnas.97.8.3930  1
2000 Wurtz NR, Dervan PB. Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates. Chemistry & Biology. 7: 153-61. PMID 10712931 DOI: 10.1016/S1074-5521(00)00085-5  1
2000 Kielkopf CL, Bremer RE, White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB, Rees DC. Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove. Journal of Molecular Biology. 295: 557-67. PMID 10623546 DOI: 10.1006/jmbi.1999.3364  1
2000 Chang AY, Dervan PB. Strand selective cleavage of DNA by diastereomers of hairpin polyamide- seco-CBI conjugates Journal of the American Chemical Society. 122: 4856-4864. DOI: 10.1021/ja994345x  1
2000 Ellervik U, Wang CCC, Dervan PB. Hydroxybenzamide/pyrrole pair distinguishes T·A from A·T base pairs in the minor groove of DNA Journal of the American Chemical Society. 122: 9354-9360. DOI: 10.1021/ja001692u  1
2000 Floreancig PE, Swalley SE, Trauger JW, Dervan PB. Recognition of the minor groove of DNA by hairpin polyamides containing α-substituted-β-amino acids Journal of the American Chemical Society. 122: 6342-6350. DOI: 10.1021/ja000509u  1
2000 Hawkins CA, Peláez De Clairac R, Dominey RN, Baird EE, White S, Dervan PB, Wemmer DE. Controlling binding orientation in hairpin polyamide DNA complexes Journal of the American Chemical Society. 122: X. DOI: 10.1021/ja0001198  1
2000 Minehan TG, Gottwald K, Dervan PB. Molecular recognition of DNA by Hoechst benzimidazoles: Exploring beyond the pyrrole-imidazole-hydroxypyrrole polyamide-pairing code Helvetica Chimica Acta. 83: 2197-2213. DOI: 10.1002/1522-2675(20000906)83:9<2197::AID-HLCA2197>3.0.CO;2-N  1
2000 Mapp AK, Dervan PB. Preparation of thioesters for the ligation of peptides with non-native substrates Tetrahedron Letters. 41: 9451-9454.  1
2000 Hawkins CA, Peláez De Clairac R, Dominey RN, Baird EE, White S, Dervan PB, Wemmer DE. Controlling binding orientation in hairpin polyamide DNA complexes Journal of the American Chemical Society. 122: X.  1
1999 Dervan PB, Bürli RW. Sequence-specific DNA recognition by polyamides. Current Opinion in Chemical Biology. 3: 688-93. PMID 10600731 DOI: 10.1016/S1367-5931(99)00027-7  1
1999 Lenzmeier BA, Baird EE, Dervan PB, Nyborg JK. The tax protein-DNA interaction is essential for HTLV-I transactivation in vitro. Journal of Molecular Biology. 291: 731-44. PMID 10452885 DOI: 10.1006/jmbi.1999.2969  1
1999 Dickinson LA, Trauger JW, Baird EE, Ghazal P, Dervan PB, Gottesfeld JM. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides. Biochemistry. 38: 10801-7. PMID 10451376 DOI: 10.1021/bi9912847  1
1999 Dickinson LA, Trauger JW, Baird EE, Dervan PB, Graves BJ, Gottesfeld JM. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. The Journal of Biological Chemistry. 274: 12765-73. PMID 10212261 DOI: 10.1074/jbc.274.18.12765  1
1999 McBryant SJ, Baird EE, Trauger JW, Dervan PB, Gottesfeld JM. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand. Journal of Molecular Biology. 286: 973-81. PMID 10047474 DOI: 10.1006/jmbi.1999.2539  1
1999 Pilch DS, Poklar N, Baird EE, Dervan PB, Breslauer KJ. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA. Biochemistry. 38: 2143-51. PMID 10026298 DOI: 10.1021/bi982628g  1
1999 Urbach AR, Szewczyk JW, White S, Turner JM, Baird EE, Dervan PB. Sequence selectivity of 3-hydroxypyrrole/pyrrole ring pairings in the DNA minor groove Journal of the American Chemical Society. 121: 11621-11629. DOI: 10.1021/ja9930667  1
1999 De Clairac RPL, Seel CJ, Geierstanger BH, Mrksich M, Baird EE, Dervan PB, Wemmer DE. NMR characterization of the aliphatic β/β pairing for recognition of A·T/T·A base pairs in the minor groove of DNA Journal of the American Chemical Society. 121: 2956-2964. DOI: 10.1021/ja983671u  1
1999 Herman DM, Turner JM, Baird EE, Dervan PB. Cycle polyamide motif for recognition of the minor groove of DNA Journal of the American Chemical Society. 121: 1121-1129. DOI: 10.1021/ja983206x  1
1999 Swalley SE, Baird EE, Dervan PB. Effects of γ-Turn and β-Tail Amino Acids on Sequence-Specific Recognition of DNA by Hairpin Polyamides Journal of the American Chemical Society. 121: X-1119. DOI: 10.1021/ja9830905  1
1999 White S, Turner JM, Szewczyk JW, Baird EE, Dervan PB. Affinity and specificity of multiple hydroxypyrrole/pyrrole ring pairings for coded recognition of DNA [8] Journal of the American Chemical Society. 121: 260-261. DOI: 10.1021/ja9830593  1
1999 Herman DM, Baird EE, Dervan PB. Tandem hairpin motif for recognition in the minor groove of DNA by pyrrole - Imidazole polyamides Chemistry - a European Journal. 5: 975-983.  1
1998 Trauger JW, Baird EE, Dervan PB. Cooperative Hairpin Dimers for Recognition of DNA by Pyrrole-Imidazole Polyamides. Angewandte Chemie (International Ed. in English). 37: 1421-1423. PMID 29710894 DOI: 10.1002/(SICI)1521-3773(19980605)37:10<1421::AID-ANIE1421>3.0.CO;2-8  0.88
1998 Dickinson LA, Gulizia RJ, Trauger JW, Baird EE, Mosier DE, Gottesfeld JM, Dervan PB. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proceedings of the National Academy of Sciences of the United States of America. 95: 12890-5. PMID 9789010 DOI: 10.1073/pnas.95.22.12890  1
1998 Kielkopf CL, White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB, Rees DC. A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA. Science (New York, N.Y.). 282: 111-5. PMID 9756473 DOI: 10.1126/science.282.5386.111  1
1998 Bremer RE, Baird EE, Dervan PB. Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch. Chemistry & Biology. 5: 119-33. PMID 9545429  1
1998 White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB. Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature. 391: 468-71. PMID 9461213 DOI: 10.1038/35106  1
1998 Kielkopf CL, Baird EE, Dervan PB, Rees DC. Structural basis for G.C recognition in the DNA minor groove. Nature Structural Biology. 5: 104-9. PMID 9461074 DOI: 10.1038/nsb0298-104  1
1998 Turner JM, Swalley SE, Baird EE, Dervan PB. Aliphatic/aromatic amino acid pairings for polyamide recognition in the minor groove of DNA Journal of the American Chemical Society. 120: 6219-6226. DOI: 10.1021/ja980147e  1
1998 Herman DM, Baird EE, Dervan PB. Stereochemical control of the DNA binding affinity, sequence specificity, and orientation preference of chiral hairpin polyamides in the minor groove Journal of the American Chemical Society. 120: 1382-1391. DOI: 10.1021/ja9737228  1
1998 Trauger JW, Baird EE, Dervan PB. Cooperative hairpin dimers for recognition of DNA by pyrrole-imidazole polyamides Angewandte Chemie - International Edition. 37: 1421-1423. DOI: 10.1002/(SICI)1521-3773(19980605)37:10<1421::AID-ANIE1421>3.0.CO;2-8  1
1998 Greenberg WA, Baird EE, Dervan PB. A comparison of H-pin and hairpin polyamide motifs for the recognition of the minor groove of DNA Chemistry - a European Journal. 4: 796-805. DOI: 10.1002/(SICI)1521-3765(19980515)4:5<796::AID-CHEM796>3.0.CO;2-G  1
1997 Neely L, Trauger JW, Baird EE, Dervan PB, Gottesfeld JM. Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex. Journal of Molecular Biology. 274: 439-45. PMID 9417925 DOI: 10.1006/jmbi.1997.1411  1
1997 White S, Baird EE, Dervan PB. On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides. Chemistry & Biology. 4: 569-78. PMID 9281524  1
1997 Wemmer DE, Dervan PB. Targeting the minor groove of DNA. Current Opinion in Structural Biology. 7: 355-61. PMID 9204277 DOI: 10.1016/S0959-440X(97)80051-6  1
1997 Taylor MJ, Dervan PB. Kinetic analysis of sequence-specific alkylation of DNA by pyrimidine oligodeoxyribonucleotide-directed triple-helix formation. Bioconjugate Chemistry. 8: 354-64. PMID 9177841 DOI: 10.1021/bc970035x  1
1997 Gottesfeld JM, Neely L, Trauger JW, Baird EE, Dervan PB. Regulation of gene expression by small molecules. Nature. 387: 202-5. PMID 9144294 DOI: 10.1038/387202a0  1
1997 Koshlap KM, Schultze P, Brunar H, Dervan PB, Feigon J. Solution structure of an intramolecular DNA triplex containing an N7- glycosylated guanine which mimics a protonated cytosine Biochemistry. 36: 2659-2668. PMID 9054573 DOI: 10.1021/bi962438a  1
1997 White S, Baird EE, Dervan PB. Orientation preferences of pyrrole-imidazole polyamides in the minor groove of DNA Journal of the American Chemical Society. 119: 8756-8765. DOI: 10.1021/ja971569b  1
1997 Turner JM, Baird EE, Dervan PB. Recognition of seven base pair sequences in the minor groove of DNA by ten-ring pyrrole-imidazole polyamide hairpins Journal of the American Chemical Society. 119: 7636-7644. DOI: 10.1021/ja971208w  1
1997 Swalley SE, Baird EE, Dervan PB. Discrimination of 5'-GGGG-3', 5'-GCGC-3', and 5'-GGCC-3' sequences in the minor groove of DNA by eight-ring hairpin polyamides Journal of the American Chemical Society. 119: 6953-6961. DOI: 10.1021/ja971184t  1
1997 Lamamie De Clairac RP, Geierstanger BH, Mrksich M, Dervan PB, Wemmer DE. NMR characterization of hairpin polyamide complexes with the minor groove of DNA Journal of the American Chemical Society. 119: 7909-7916. DOI: 10.1021/ja964314r  1
1997 Lehmann TE, Greenberg WA, Liberies DA, Wada CK, Dervan PB. Triple-helix formation by pyrimidine oligonucleotide containing nonnatural nucleosides with extended aromatic nucleobases: Intercalation from the major groove as a method for recognizing C·G and T·A base pairs Helvetica Chimica Acta. 80: 2002-2022. DOI: 10.1002/hlca.19970800618  1
1997 Dervan PB. Gene-specific transcription inhibition in vivo by designed ligands Faseb Journal. 11: A1291.  1
1997 Swalley SE, Baird EE, Dervan PB. A pyrrole-imidazole polyamide motif for recognition of eleven base pair sequences in the minor groove of DNA Chemistry - a European Journal. 3: 1600-1607.  1
1996 Parks ME, Dervan PB. Simultaneous binding of a polyamide dimer and an oligonucleotide in the minor and major grooves of DNA. Bioorganic & Medicinal Chemistry. 4: 1045-50. PMID 8831975 DOI: 10.1016/0968-0896(96)00089-2  1
1996 White S, Baird EE, Dervan PB. Effects of the A.T/T.A degeneracy of pyrrole--imidazole polyamide recognition in the minor groove of DNA. Biochemistry. 35: 12532-7. PMID 8823190 DOI: 10.1021/bi960744i  1
1996 Grant KB, Dervan PB. Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation. Biochemistry. 35: 12313-9. PMID 8823165 DOI: 10.1021/bi9608469  1
1996 Trauger JW, Baird EE, Dervan PB. Extended hairpin polyamide motif for sequence-specific recognition in the minor groove of DNA. Chemistry & Biology. 3: 369-77. PMID 8807866  1
1996 Liberles DA, Dervan PB. Design of artificial sequence-specific DNA bending ligands. Proceedings of the National Academy of Sciences of the United States of America. 93: 9510-4. PMID 8790361 DOI: 10.1073/pnas.93.18.9510  1
1996 Pilch DS, Poklar N, Gelfand CA, Law SM, Breslauer KJ, Baird EE, Dervan PB. Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination. Proceedings of the National Academy of Sciences of the United States of America. 93: 8306-11. PMID 8710866  1
1996 Trauger JW, Baird EE, Dervan PB. Recognition of DNA by designed ligands at subnanomolar concentrations. Nature. 382: 559-61. PMID 8700233 DOI: 10.1038/382559a0  1
1996 Kelly JJ, Baird EE, Dervan PB. Binding site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif. Proceedings of the National Academy of Sciences of the United States of America. 93: 6981-5. PMID 8692930 DOI: 10.1073/pnas.93.14.6981  1
1996 Brunar H, Dervan PB. Sequence composition effects on the stabilities of triple helix formation by oligonucleotides containing N7-deoxyguanosine. Nucleic Acids Research. 24: 1987-91. PMID 8668526 DOI: 10.1093/nar/24.11.1987  1
1996 Wang E, Koshlap KM, Gillespie P, Dervan PB, Feigon J. Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. Journal of Molecular Biology. 257: 1052-69. PMID 8632468 DOI: 10.1006/jmbi.1996.0223  1
1996 Geierstanger BH, Mrksich M, Dervan PB, Wemmer DE. Extending the recognition site of designed minor groove binding molecules. Nature Structural Biology. 3: 321-4. PMID 8599756 DOI: 10.1038/nsb0496-321  1
1996 Swalley SE, Baird EE, Dervan PB. Recognition of a 5'-(A,T)GGG(A,T)2-3' sequence in the minor groove of DNA by an eight-ring hairpin polyamide Journal of the American Chemical Society. 118: 8198-8206. DOI: 10.1021/ja9611598  1
1996 Szewczyk JW, Baird EE, Dervan PB. Cooperative triple-helix formation via a minor groove dimerization domain Journal of the American Chemical Society. 118: 6778-6779. DOI: 10.1021/ja960831y  1
1996 Parks ME, Baird EE, Dervan PB. Recognition of 5'-(A,T)GG(A,T)2-3' sequences in the minor groove of DNA by hairpin polyamides Journal of the American Chemical Society. 118: 6153-6159. DOI: 10.1021/ja9607289  1
1996 Trauger JW, Baird EE, Mrksich M, Dervan PB. Extension of sequence-specific recognition in the minor groove of DNA by pyrrole-imidazole polyamides to 9-13 base pairs Journal of the American Chemical Society. 118: 6160-6166. DOI: 10.1021/ja960726o  1
1996 Parks ME, Baird EE, Dervan PB. Optimization of the hairpin polyamide design for recognition of the minor groove of DNA Journal of the American Chemical Society. 118: 6147-6152. DOI: 10.1021/ja960721r  1
1996 Baird EE, Dervan PB. Solid phase synthesis of polyamides containing imidazole and pyrrole amino acids Journal of the American Chemical Society. 118: 6141-6146. DOI: 10.1021/ja960720z  1
1996 Szewczyk JW, Baird EE, Dervan PB. Sequence-specific recognition of DNA by a major and minor groove binding ligand Angewandte Chemie (International Edition in English). 35: 1487-1489.  1
1995 Chen L, Oakley MG, Glover JN, Jain J, Dervan PB, Hogan PG, Rao A, Verdine GL. Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp. Current Biology : Cb. 5: 882-9. PMID 7583146 DOI: 10.1016/S0960-9822(95)00178-3  0.48
1995 Baliga R, Singleton JW, Dervan PB. RecA.oligonucleotide filaments bind in the minor groove of double-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America. 92: 10393-7. PMID 7479791 DOI: 10.1073/pnas.92.22.10393  1
1995 Cho J, Parks ME, Dervan PB. Cyclic polyamides for recognition in the minor groove of DNA. Proceedings of the National Academy of Sciences of the United States of America. 92: 10389-92. PMID 7479790 DOI: 10.1073/pnas.92.22.10389  1
1995 Hunziker J, Priestley ES, Brunar H, Dervan PB. Design of an N7-glycosylated purine nucleoside for recognition of GC base pairs by triple helix formation Journal of the American Chemical Society. 117: 2661-2662. DOI: 10.1021/ja00114a036  1
1995 Greenberg WA, Dervan PB. Energetics of formation of sixteen triple helical complexes which vary at a single position within a purine motif Journal of the American Chemical Society. 117: 5016-5019.  1
1995 Colocci N, Dervan PB. Cooperative triple-helix formation at adjacent DNA sites: Sequence composition dependence at the junction Journal of the American Chemical Society. 117: 4781-4787.  1
1995 Mrksich M, Dervan PB. Recognition in the minor groove of DNA at 5′-(A,T)GCGC(A,T)-3′ by a four ring tripeptide dimer. Reversal of the specificity of the natural product distamycin Journal of the American Chemical Society. 117: 3325-3332.  1
1995 Best GC, Dervan PB. Energetics of formation of sixteen triple helical complexes which vary at a single position within a pyrimidine motif Journal of the American Chemical Society. 117: X-1193.  1
1995 Priestley ES, Dervan PB. Sequence composition effects on the energetics of triple helix formation by oligonucleotides containing a designed mimic of protonated cytosine Journal of the American Chemical Society. 117: 4761-4765.  1
1994 Han H, Dervan PB. Visualization of RNA tertiary structure by RNA-EDTA.Fe(II) autocleavage: analysis of tRNA(Phe) with uridine-EDTA.Fe(II) at position 47. Proceedings of the National Academy of Sciences of the United States of America. 91: 4955-9. PMID 8197164  0.64
1994 Hacia JG, Dervan PB, Wold BJ. Inhibition of Klenow fragment DNA polymerase on double-helical templates by oligonucleotide-directed triple-helix formation. Biochemistry. 33: 6192-200. PMID 8193133  1
1994 Hacia JG, Wold BJ, Dervan PB. Phosphorothioate oligonucleotide-directed triple helix formation. Biochemistry. 33: 5367-9. PMID 8180158  1
1994 Han H, Schepartz A, Pellegrini M, Dervan PB. Mapping RNA regions in eukaryotic ribosomes that are accessible to methidiumpropyl-EDTA.Fe(II) and EDTA.Fe(II). Biochemistry. 33: 9831-44. PMID 8060991  1
1994 Geierstanger BH, Mrksich M, Dervan PB, Wemmer DE. Design of a G.C-specific DNA minor groove-binding peptide. Science (New York, N.Y.). 266: 646-50. PMID 7939719  1
1994 Oakley MG, Turnbull KD, Dervan PB. Synthesis of a hybrid protein containing the iron-binding ligand of bleomycin and the DNA-binding domain of Hin. Bioconjugate Chemistry. 5: 242-7. PMID 7522582  1
1994 Han H, Dervan PB. Different conformational families of pyrimidine.purine.pyrimidine triple helices depending on backbone composition. Nucleic Acids Research. 22: 2837-44. PMID 7519770  0.64
1994 Singleton SF, Dervan PB. Temperature dependence of the energetics of oligonucleotide-directed triple-helix formation at a single DNA site Journal of the American Chemical Society. 116: 10376-10382.  1
1993 Iverson BL, Dervan PB. Adenine-specific DNA chemical sequencing reaction. Methods in Enzymology. 218: 222-7. PMID 8510534  1
1993 Distefano MD, Dervan PB. Energetics of cooperative binding of oligonucleotides with discrete dimerization domains to DNA by triple helix formation. Proceedings of the National Academy of Sciences of the United States of America. 90: 1179-83. PMID 8433980  1
1993 Feng JA, Simon M, Mack DP, Dervan PB, Johnson RC, Dickerson RE. Crystallization and preliminary X-ray analysis of the DNA binding domain of the Hin recombinase with its DNA binding site. Journal of Molecular Biology. 232: 982-6. PMID 8355281 DOI: 10.1006/jmbi.1993.1443  1
1993 Wade WS, Mrksich M, Dervan PB. Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA. Biochemistry. 32: 11385-9. PMID 8218203  1
1993 Han H, Dervan PB. Sequence-specific recognition of double helical RNA and RNA.DNA by triple helix formation. Proceedings of the National Academy of Sciences of the United States of America. 90: 3806-10. PMID 7683407  0.64
1992 Maher LJ, Dervan PB, Wold B. Analysis of promoter-specific repression by triple-helical DNA complexes in a eukaryotic cell-free transcription system. Biochemistry. 31: 70-81. PMID 1731886  1
1992 Beal PA, Dervan PB. The influence of single base triplet changes on the stability of a pur.pur.pyr triple helix determined by affinity cleaving. Nucleic Acids Research. 20: 2773-6. PMID 1614865  1
1992 Kiessling LL, Griffin LC, Dervan PB. Flanking sequence effects within the pyrimidine triple-helix motif characterized by affinity cleaving. Biochemistry. 31: 2829-34. PMID 1547224  1
1992 Oakley MG, Mrksich M, Dervan PB. Evidence that a minor groove-binding peptide and a major groove-binding protein can simultaneously occupy a common site on DNA. Biochemistry. 31: 10969-75. PMID 1445835  1
1992 Mack DP, Dervan PB. Sequence-specific oxidative cleavage of DNA by a designed metalloprotein, Ni(II).GGH(Hin139-190). Biochemistry. 31: 9399-405. PMID 1390723  0.32
1992 Strobel SA, Dervan PB. Triple helix-mediated single-site enzymatic cleavage of megabase genomic DNA. Methods in Enzymology. 216: 309-21. PMID 1336095 DOI: 10.1016/0076-6879(92)16029-J  1
1992 Mrksich M, Wade WS, Dwyer TJ, Geierstanger BH, Wemmer DE, Dervan PB. Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin. Proceedings of the National Academy of Sciences of the United States of America. 89: 7586-90. PMID 1323845  1
1991 Beal PA, Dervan PB. Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation. Science (New York, N.Y.). 251: 1360-3. PMID 2003222  1
1991 Shin JA, Ebright RH, Dervan PB. Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving. Nucleic Acids Research. 19: 5233-6. PMID 1923807 DOI: 10.1093/nar/19.19.5227  1
1991 Horne DA, Dervan PB. Effects of an abasic site on triple helix formation characterized by affinity cleaving. Nucleic Acids Research. 19: 4963-5. PMID 1923764  1
1991 Strobel SA, Dervan PB. Single-site enzymatic cleavage of yeast genomic DNA mediated by triple helix formation. Nature. 350: 172-4. PMID 1848684 DOI: 10.1038/350172a0  1
1991 Strobel SA, Doucette-Stamm LA, Riba L, Housman DE, Dervan PB. Site-specific cleavage of human chromosome 4 mediated by triple-helix formation. Science (New York, N.Y.). 254: 1639-42. PMID 1836279  1
1991 Maher LJ, Wold B, Dervan PB. Oligonucleotide-directed DNA triple-helix formation: an approach to artificial repressors? Antisense Research and Development. 1: 277-81. PMID 1821648  1
1990 Maher LJ, Dervan PB, Wold BJ. Kinetic analysis of oligodeoxyribonucleotide-directed triple-helix formation on DNA. Biochemistry. 29: 8820-6. PMID 2271558  1
1990 Plum GE, Park YW, Singleton SF, Dervan PB, Breslauer KJ. Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: a spectroscopic and calorimetric study. Proceedings of the National Academy of Sciences of the United States of America. 87: 9436-40. PMID 2251285  1
1990 Mack DP, Sluka JP, Shin JA, Griffin JH, Simon MI, Dervan PB. Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the hix site. Biochemistry. 29: 6561-7. PMID 2204416  0.32
1990 Strobel SA, Dervan PB. Site-specific cleavage of a yeast chromosome by oligonucleotide-directed triple-helix formation. Science (New York, N.Y.). 249: 73-5. PMID 2195655  1
1990 Graham KS, Dervan PB. Structural motif of the DNA binding domain of gamma delta-resolvase characterized by affinity cleaving. The Journal of Biological Chemistry. 265: 16534-40. PMID 2168893  1
1990 Oakley MG, Dervan PB. Structural motif of the GCN4 DNA binding domain characterized by affinity cleaving. Science (New York, N.Y.). 248: 847-50. PMID 2111578  0.6
1989 Wang AH, Cottens S, Dervan PB, Yesinowski JP, van der Marel GA, van Boom JH. Interactions between a symmetrical minor groove binding compound and DNA oligonucleotides: 1H and 19F NMR studies. Journal of Biomolecular Structure & Dynamics. 7: 101-17. PMID 2818866 DOI: 10.1080/07391102.1989.10507754  1
1989 Griffin LC, Dervan PB. Recognition of thymine adenine.base pairs by guanine in a pyrimidine triple helix motif. Science (New York, N.Y.). 245: 967-71. PMID 2549639  0.52
1989 Maher LJ, Wold B, Dervan PB. Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation. Science (New York, N.Y.). 245: 725-30. PMID 2549631  1
1988 Iverson BL, Dervan PB. Nonenzymatic sequence-specific methyl transfer to single-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 4615-9. PMID 3387429  1
1987 Iverson BL, Dervan PB. Adenine specific DNA chemical sequencing reaction. Nucleic Acids Research. 15: 7823-30. PMID 3671067 DOI: 10.1093/nar/15.19.7823  1
1987 Mendel D, Dervan PB. Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA. Proceedings of the National Academy of Sciences of the United States of America. 84: 910-4. PMID 3103127  0.92
1984 Schultz PG, Dervan PB. Distamycin and penta-N-methylpyrrolecarboxamide binding sites on native DNA. A comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity cleaving. Journal of Biomolecular Structure & Dynamics. 1: 1133-47. PMID 6101078 DOI: 10.1080/07391102.1984.10507508  1
1983 Schultz PG, Dervan PB. Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA X Fe(II). Proceedings of the National Academy of Sciences of the United States of America. 80: 6834-7. PMID 6417654  1
Show low-probability matches.