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Year Citation  Score
2013 Van Amerongen R, Berns A. Break the loop, escape the cycle? Embo Journal. 32: 1967-1969. PMID 23749211 DOI: 10.1038/emboj.2013.137  0.554
2012 Walf-Vorderwülbecke V, de Boer J, Horton SJ, van Amerongen R, Proost N, Berns A, Williams O. Frat2 mediates the oncogenic activation of Rac by MLL fusions. Blood. 120: 4819-28. PMID 23074275 DOI: 10.1182/blood-2012-05-432534  0.605
2006 van Amerongen R, Berns A. Knockout mouse models to study Wnt signal transduction Trends in Genetics. 22: 678-689. PMID 17045694 DOI: 10.1016/j.tig.2006.10.001  0.611
2006 Van Amerongen R, Berns A. TXR1-mediated thrombospondin repression: A novel mechanism of resistance to taxanes? Genes and Development. 20: 1975-1981. PMID 16882973 DOI: 10.1101/gad.1460806  0.566
2005 Van Amerongen R, Nawijn M, Franca-Koh J, Zevenhoven J, Van Der Gulden H, Jonkers J, Berns A. Frat is dispensable for canonical Wnt signaling in mammals Genes and Development. 19: 425-430. PMID 15681612 DOI: 10.1101/gad.326705  0.616
2004 Robanus-Maandag E, Giovannini M, Van Der Valk M, Niwa-Kawakita M, Abramowski V, Antonescu C, Thomas G, Berns A. Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin Oncogene. 23: 6541-6547. PMID 15221010 DOI: 10.1038/Sj.Onc.1207858  0.552
2004 Van Amerongen R, Van Der Gulden H, Bleeker F, Jonkers J, Berns A. Characterization and functional analysis of the murine Frat2 gene Journal of Biological Chemistry. 279: 26967-26974. PMID 15073180 DOI: 10.1074/jbc.M400439200  0.622
1974 Berns AJ, Bloemendal H. Translation of mRNA from vertebrate eye lenses. Methods in Enzymology. 30: 675-94. PMID 4859573 DOI: 10.1016/0076-6879(74)30065-1  0.404
1974 Strous GJ, Berns AJ, Bloemendal H. N-terminal acetylation of the nascent chains of alpha-crystallin. Biochemical and Biophysical Research Communications. 58: 876-84. PMID 4836280 DOI: 10.1016/S0006-291X(74)80498-5  0.39
1974 Berns A, Janssen P, Bloemendal H. The molecular weight of the 14S calf lens messenger RNA. Biochemical and Biophysical Research Communications. 59: 1157-64. PMID 4472373 DOI: 10.1016/S0006-291X(74)80100-2  0.418
1974 Piperno G, Bertazzoni U, Berns AJ, Bloemendal H. Calf lens crystallin messenger RNA's contain polynucleotide sequences rich in adenylic acid. Nucleic Acids Research. 1: 245-55. PMID 4472020 DOI: 10.1093/Nar/1.2.245  0.412
1973 Berns AJ, Bloemendal H, Kaufman SJ, Verma IM. Synthesis of DNA complementary to 14S calf lens crystallin messenger RNA by reverse transcriptase. Biochemical and Biophysical Research Communications. 52: 1013-9. PMID 4122882 DOI: 10.1016/0006-291X(73)91038-3  0.417
1972 Bloemendal H, Berns AJ, van der Ouderaa F, de Jong WW. Evidence for a "non-genetic" origin of the A1 chains of alpha-crystallin. Experimental Eye Research. 14: 80-1. PMID 5039850 DOI: 10.1016/0014-4835(72)90147-9  0.354
1972 Berns AJ, van Kraaikamp M, Bloemendal H, Lane CD. Calf crystallin synthesis in frog cells: the translation of lens-cell 14S RNA in oocytes. Proceedings of the National Academy of Sciences of the United States of America. 69: 1606-9. PMID 4504377 DOI: 10.1073/Pnas.69.6.1606  0.443
1972 Berns AJ, Strous GJ, Bloemendal H. Heterologous in vitro synthesis of lens -crystallin polypeptide. Nature: New Biology. 236: 7-9. PMID 4502421 DOI: 10.1038/Newbio236007A0  0.437
1972 Mathews MB, Osborn M, Berns AJ, Bloemendal H. Translation of two messenger RNAs from lens in a cell free system from Krebs II ascites cells. Nature: New Biology. 236: 5-7. PMID 4502420 DOI: 10.1038/Newbio236005A0  0.439
1971 Berns AJ, De Abreu RA, Van Kraaikamp M, Benedetti EL, Bloemendal H. Synthesis of lens protein in vitro V. Isolation of messenger-like RNA from lens by high resolution zonal centrifugation. Febs Letters. 18: 159-163. PMID 11946110 DOI: 10.1016/0014-5793(71)80434-9  0.447
1971 Berns AJ, Zweers A, Gribnau AA, Bloemendal H. Proteolytic activity of partly purified ribonuclease inhibitor from rat liver. Biochimica Et Biophysica Acta. 247: 62-5. PMID 5160756 DOI: 10.1016/0005-2787(71)90807-0  0.375
Low-probability matches (unlikely to be authored by this person)
2010 Van Amerongen R, Nawijn MC, Lambooij JP, Proost N, Jonkers J, Berns A. Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways Oncogene. 29: 93-104. PMID 19802005 DOI: 10.1038/onc.2009.310  0.228
2011 Nawijn MC, Alendar A, Berns A. For better or for worse: The role of Pim oncogenes in tumorigenesis Nature Reviews Cancer. 11: 23-34. PMID 21150935 DOI: 10.1038/nrc2986  0.22
2002 Marino S, Krimpenfort P, Leung C, van der Korput HA, Trapman J, Camenisch I, Berns A, Brandner S. PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum. Development (Cambridge, England). 129: 3513-22. PMID 12091320  0.204
2007 Krimpenfort P, IJpenberg A, Song JY, Van Der Valk M, Nawijn M, Zevenhoven J, Berns A. p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a Nature. 448: 943-946. PMID 17713536 DOI: 10.1038/nature06084  0.202
2002 Mikkers H, Allen J, Knipscheer P, Romeyn L, Hart A, Vink E, Berns A. High-throughput retroviral tagging to identify components of specific signaling pathways in cancer Nature Genetics. 32: 153-159. PMID 12185366 DOI: 10.1038/Ng950  0.202
2004 Mikkers H, Nawijn M, Allen J, Brouwers C, Verhoeven E, Jonkers J, Berns A. Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors Molecular and Cellular Biology. 24: 6104-6115. PMID 15199164 DOI: 10.1128/MCB.24.13.6104-6115.2004  0.198
2002 Mikkers H, Allen J, Berns A. Proviral activation of the tumor suppressor E2a contributes to T cell lymphomagenesis in EμMyc transgenic mice Oncogene. 21: 6559-6566. PMID 12242653 DOI: 10.1038/sj.onc.1205930  0.195
2005 Van Amerongen R, Berns A. Re-evaluating the role of Frat in Wnt-signal transduction Cell Cycle. 4: e89-e96.  0.182
2006 Shakhova O, Leung C, Van Montfort E, Berns A, Marino S. Lack of Rb and p53 delays cerebellar development and predisposes to large cell anaplastic medulloblastoma through amplification of N-Myc and Ptch2 Cancer Research. 66: 5190-5200. PMID 16707443 DOI: 10.1158/0008-5472.CAN-05-3545  0.181
2002 Vooijs M, Te Riele H, Van der Valk M, Berns A. Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells Oncogene. 21: 4635-4645. PMID 12096340 DOI: 10.1038/sj.onc.1205575  0.176
2004 Ruiz S, Santos M, Segrelles C, Leis H, Jorcano JL, Berns A, Paramio JM, Vooijs M. Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis Development. 131: 2737-2748. PMID 15148303 DOI: 10.1242/dev.01148  0.174
2016 Serresi M, Gargiulo G, Proost N, Siteur B, Cesaroni M, Koppens M, Xie H, Sutherland KD, Hulsman D, Citterio E, Orkin S, Berns A, van Lohuizen M. Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer Cancer Cell. 29: 17-31. DOI: 10.1016/J.Ccell.2015.12.006  0.171
2007 Hameyer D, Loonstra A, Eshkind L, Schmitt S, Antunes C, Groen A, Bindels E, Jonkers J, Krimpenfort P, Meuwissen R, Rijswijk L, Bex A, Berns A, Bockamp E. Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues Physiological Genomics. 31: 32-41. PMID 17456738 DOI: 10.1152/physiolgenomics.00019.2007  0.17
2003 Mikkers H, Berns A. Retroviral insertional mutagenesis: Tagging cancer pathways Advances in Cancer Research. 88: 53-99. PMID 12665053 DOI: 10.1016/S0065-230X(03)88255-6  0.17
2008 Berns A. A tRNA with Oncogenic Capacity Cell. 133: 29-30. PMID 18394985 DOI: 10.1016/j.cell.2008.03.017  0.17
2015 Huijbers IJ, Del Bravo J, Bin Ali R, Pritchard C, Braumuller TM, van Miltenburg MH, Henneman L, Michalak EM, Berns A, Jonkers J. Using the GEMM-ESC strategy to study gene function in mouse models. Nature Protocols. 10: 1755-85. PMID 26492136 DOI: 10.1038/nprot.2015.114  0.169
2011 March HN, Rust AG, Wright NA, ten Hoeve J, de Ridder J, Eldridge M, van der Weyden L, Berns A, Gadiot J, Uren A, Kemp R, Arends MJ, Wessels LF, Winton DJ, Adams DJ. Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis. Nature Genetics. 43: 1202-9. PMID 22057237 DOI: 10.1038/Ng.990  0.167
1975 Reijnders L, Aalberg AM, Kammen AK, Berns AJ. The effect of double-stranded cowpea mosaic viral RNA on protein synthesis. Biochimica Et Biophysica Acta. 390: 69-77. PMID 1092369 DOI: 10.1016/0005-2787(75)90009-X  0.165
2007 Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, ... ... Berns A, et al. Pim-1 regulates cardiomyocyte survival downstream of Akt Nature Medicine. 13: 1467-1475. PMID 18037896 DOI: 10.1038/Nm1671  0.163
2010 Kool J, Uren AG, Martins CP, Sie D, de Ridder J, Turner G, van Uitert M, Matentzoglu K, Lagcher W, Krimpenfort P, Gadiot J, Pritchard C, Lenz J, Lund AH, Jonkers J, ... ... Berns A, et al. Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes. Cancer Research. 70: 520-31. PMID 20068150 DOI: 10.1158/0008-5472.Can-09-2736  0.162
2010 Mattison J, Kool J, Uren AG, de Ridder J, Wessels L, Jonkers J, Bignell GR, Butler A, Rust AG, Brosch M, Wilson CH, van der Weyden L, Largaespada DA, Stratton MR, Futreal PA, ... ... Berns A, et al. Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach. Cancer Research. 70: 883-95. PMID 20103622 DOI: 10.1158/0008-5472.Can-09-1737  0.159
1996 Brady HJ, Salomons GS, Bobeldijk RC, Berns AJ. T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53. The Embo Journal. 15: 1221-30. PMID 8635454  0.159
2003 Marino S, Hoogervoorst D, Brandner S, Berns A. Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence. Development (Cambridge, England). 130: 3359-68. PMID 12810584 DOI: 10.1242/Dev.00553  0.156
2002 Hwang HC, Martins CP, Bronkhorst Y, Randel E, Berns A, Fero M, Clurman BE. Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis Proceedings of the National Academy of Sciences of the United States of America. 99: 11293-11298. PMID 12151601 DOI: 10.1073/Pnas.162356099  0.155
2002 Martins CP, Berns A. Loss of p27Kip1 but not p21Cip1 decreases survival and synergizes with MYC in murine lymphomagenesis Embo Journal. 21: 3739-3748. PMID 12110586 DOI: 10.1093/emboj/cdf364  0.151
2012 Krimpenfort P, Song JY, Proost N, Zevenhoven J, Jonkers J, Berns A. Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours Nature. 482: 538-541. PMID 22358843 DOI: 10.1038/nature10790  0.15
1984 Selten G, Cuypers H, Zijlstra M, Melief C, Berns A. Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation. The Embo Journal. 3: 3215-3222. DOI: 10.1002/j.1460-2075.1984.tb02281.x  0.15
2015 Kwon MC, Proost N, Song JY, Sutherland KD, Zevenhoven J, Berns A. Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis. Genes & Development. 29: 1587-92. PMID 26215568 DOI: 10.1101/gad.262998.115  0.149
2014 Zeilstra J, Joosten SP, van Andel H, Tolg C, Berns A, Snoek M, van de Wetering M, Spaargaren M, Clevers H, Pals ST. Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling. Oncogene. 33: 665-70. PMID 23318432 DOI: 10.1038/Onc.2012.611  0.147
1986 Cuypers HT, Selten GC, Zijlstra M, de Goede RE, Melief CJ, Berns AJ. Tumor progression in murine leukemia virus-induced T-cell lymphomas: monitoring clonal selections with viral and cellular probes. Journal of Virology. 60: 230-41. PMID 3091854 DOI: 10.1128/jvi.60.1.230-241.1986  0.145
1996 Brady HJ, Gil-Gómez G, Kirberg J, Berns AJ. Bax alpha perturbs T cell development and affects cell cycle entry of T cells. The Embo Journal. 15: 6991-7001. PMID 9003775  0.144
1996 Smit JJ, Baas F, Hoogendijk JE, Jansen GH, van der Valk MA, Schinkel AH, Berns AJ, Acton D, Nooter K, Burger H, Smith SJ, Borst P. Peripheral neuropathy in mice transgenic for a human MDR3 P-glycoprotein mini-gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6386-93. PMID 8815917  0.143
2008 Jongsma J, van Montfort E, Vooijs M, Zevenhoven J, Krimpenfort P, van der Valk M, van de Vijver M, Berns A. A Conditional Mouse Model for Malignant Mesothelioma Cancer Cell. 13: 261-271. PMID 18328429 DOI: 10.1016/j.ccr.2008.01.030  0.14
2002 Jonkers J, Berns A. Conditional mouse models of sporadic cancer Nature Reviews Cancer. 2: 251-265. PMID 12001987  0.14
1994 De Wind N, Peeters BP, Zuderveld A, Gielkens AL, Berns AJ, Kimman TG. Mutagenesis and characterization of a 41-kilobase-pair region of the pseudorabies virus genome: transcription map, search for virulence genes, and comparison with homologs of herpes simplex virus type 1. Virology. 200: 784-90. PMID 8178460 DOI: 10.1006/viro.1994.1242  0.14
2013 Akhtar W, de Jong J, Pindyurin AV, Pagie L, Meuleman W, de Ridder J, Berns A, Wessels LF, van Lohuizen M, van Steensel B. Chromatin position effects assayed by thousands of reporters integrated in parallel. Cell. 154: 914-27. PMID 23953119 DOI: 10.1016/J.Cell.2013.07.018  0.136
1992 Kimman TG, Pol JM, de Wind N, Oei-Lie N, Berns AJ, Gielkens AL. Role of different genes in the virulence and pathogenesis of Aujeszky's disease virus. Veterinary Microbiology. 33: 45-52. PMID 1336250 DOI: 10.1016/0378-1135(92)90034-Q  0.136
2002 Vooijs M, Jonkers J, Lyons S, Berns A. Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice Cancer Research. 62: 1862-1867. PMID 11912166  0.134
2006 Huijbers IJ, Krimpenfort P, Chomez P, Van Der Valk MA, Song JY, Inderberg-Suso EM, Schmitt-Verhulst AM, Berns A, Van Den Eynde BJ. An inducible mouse model of melanoma expressing a defined tumor antigen Cancer Research. 66: 3278-3286. PMID 16540681 DOI: 10.1158/0008-5472.CAN-05-3216  0.133
2014 Akhtar W, Pindyurin AV, de Jong J, Pagie L, Ten Hoeve J, Berns A, Wessels LF, van Steensel B, van Lohuizen M. Using TRIP for genome-wide position effect analysis in cultured cells. Nature Protocols. 9: 1255-81. PMID 24810036 DOI: 10.1038/nprot.2014.072  0.133
2008 Uren AG, Kool J, Matentzoglu K, de Ridder J, Mattison J, van Uitert M, Lagcher W, Sie D, Tanger E, Cox T, Reinders M, Hubbard TJ, Rogers J, Jonkers J, Wessels L, ... ... Berns A, et al. Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks. Cell. 133: 727-41. PMID 18485879 DOI: 10.1016/J.Cell.2008.03.021  0.132
1987 Quint W, Gielkens A, Van Oirschot J, Berns A, Cuypers HT. Construction and characterization of deletion mutants of pseudorabies virus: a new generation of 'live' vaccines. The Journal of General Virology. 523-34. PMID 3029289 DOI: 10.1099/0022-1317-68-2-523  0.132
2002 Bex A, Vooijs M, Horenblas S, Berns A. Controlling gene expression in the urothelium using transgenic mice with inducible bladder specific Cre-lox recombination Journal of Urology. 168: 2641-2644. PMID 12442001  0.13
2005 Linnoila RI, Naizhen X, Meuwissen R, Berns A, DeMayo FJ. Mouse lung neuroendocrine carcinomas: Distinct morphologies, same transcription factors Experimental Lung Research. 31: 37-55. PMID 15765918 DOI: 10.1080/01902140490495002  0.13
2011 Sutherland KD, Proost N, Brouns I, Adriaensen D, Song JY, Berns A. Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell. 19: 754-64. PMID 21665149 DOI: 10.1016/j.ccr.2011.04.019  0.128
2005 Meuwissen R, Berns A. Mouse models for human lung cancer Genes and Development. 19: 643-664. PMID 15769940 DOI: 10.1101/gad.1284505  0.125
2005 Uren AG, Kool J, Berns A, Van Lohuizen M. Retroviral insertional mutagenesis: Past, present and future Oncogene. 24: 7656-7672. PMID 16299527 DOI: 10.1038/sj.onc.1209043  0.125
2009 Kazarian M, Calbo J, Proost N, Carpenter CL, Berns A, Laird-Offringa IA. Immune response in lung cancer mouse model mimics human anti-Hu reactivity. Journal of Neuroimmunology. 217: 38-45. PMID 19765830 DOI: 10.1016/J.Jneuroim.2009.08.014  0.124
2014 Sutherland KD, Song JY, Kwon MC, Proost N, Zevenhoven J, Berns A. Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 111: 4952-7. PMID 24586047 DOI: 10.1073/pnas.1319963111  0.121
2014 Huijbers IJ, Bin Ali R, Pritchard C, Cozijnsen M, Kwon MC, Proost N, Song JY, de Vries H, Badhai J, Sutherland K, Krimpenfort P, Michalak EM, Jonkers J, Berns A. Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells. Embo Molecular Medicine. 6: 212-25. PMID 24401838 DOI: 10.1002/emmm.201303297  0.121
2011 Calbo J, van Montfort E, Proost N, van Drunen E, Beverloo HB, Meuwissen R, Berns A. A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer Cancer Cell. 19: 244-256. PMID 21316603 DOI: 10.1016/j.ccr.2010.12.021  0.12
1992 Kimman TG, de Wind N, Oei-Lie N, Pol JM, Berns AJ, Gielkens AL. Contribution of single genes within the unique short region of Aujeszky's disease virus (suid herpesvirus type 1) to virulence, pathogenesis and immunogenicity. The Journal of General Virology. 73: 243-51. PMID 1311354 DOI: 10.1099/0022-1317-73-2-243  0.118
2004 Jonkers J, Berns A. Oncogene addiction: Sometimes a temporary slavery Cancer Cell. 6: 535-538. PMID 15607957 DOI: 10.1016/j.ccr.2004.12.002  0.116
2003 Lyons SK, Meuwissen R, Krimpenfort P, Berns A. The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice. Cancer Research. 63: 7042-6. PMID 14612492  0.115
2013 Horn KE, Glasgow SD, Gobert D, Bull SJ, Luk T, Girgis J, Tremblay ME, McEachern D, Bouchard JF, Haber M, Hamel E, Krimpenfort P, Murai KK, Berns A, Doucet G, et al. DCC expression by neurons regulates synaptic plasticity in the adult brain. Cell Reports. 3: 173-85. PMID 23291093 DOI: 10.1016/J.Celrep.2012.12.005  0.114
2011 Huijbers IJ, Krimpenfort P, Berns A, Jonkers J. Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models Bioessays. 33: 701-710. PMID 21735458 DOI: 10.1002/bies.201100018  0.113
2015 Krimpenfort P, Berns A. Wnt Down, Tumors Wind Up? Cell. 161: 1494-1496. PMID 26091030 DOI: 10.1016/j.cell.2015.06.008  0.11
1993 de Wind N, Berns A, Gielkens A, Kimman T. Ribonucleotide reductase-deficient mutants of pseudorabies virus are avirulent for pigs and induce partial protective immunity. The Journal of General Virology. 351-9. PMID 8383170 DOI: 10.1099/0022-1317-74-3-351  0.11
2010 Sutherland KD, Berns A. Cell of origin of lung cancer. Molecular Oncology. 4: 397-403. PMID 20594926 DOI: 10.1016/j.molonc.2010.05.002  0.11
2005 Calbó J, Meuwissen R, Van Montfort E, Van Tellingen O, Berns A. Genotype-phenotype relationships in a mouse model for human small-cell lung cancer Cold Spring Harbor Symposia On Quantitative Biology. 70: 225-232. PMID 16869758 DOI: 10.1101/sqb.2005.70.026  0.11
1981 Van Beveren C, Galleshaw JA, Jonas V, Berns AJ, Doolittle RF, Donoghue DJ, Verma IM. Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus. Nature. 289: 258-62. PMID 6256659 DOI: 10.1038/289258A0  0.11
2005 Ma X, Ziel-van der Made AC, Autar B, van der Korput HA, Vermeij M, van Duijn P, Cleutjens KB, de Krijger R, Krimpenfort P, Berns A, van der Kwast TH, Trapman J. Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis. Cancer Research. 65: 5730-9. PMID 15994948 DOI: 10.1158/0008-5472.CAN-04-4519  0.11
1982 Mariman EC, van Eekelen CA, Reinders RJ, Berns AJ, van Venrooij WJ. Adenoviral heterogeneous nuclear RNA is associated with the host nuclear matrix during splicing. Journal of Molecular Biology. 154: 103-19. PMID 6176712 DOI: 10.1016/0022-2836(82)90420-X  0.109
1980 Verma IM, Lai MH, Bosselman RA, McKennett MA, Fan H, Berns A. Molecular cloning of unintegrated Moloney mouse sarcoma virus DNA in bacteriophage lambda. Proceedings of the National Academy of Sciences of the United States of America. 77: 1773-7. PMID 6445561 DOI: 10.1073/Pnas.77.4.1773  0.105
2008 Lehembre F, Yilmaz M, Wicki A, Schomber T, Strittmatter K, Ziegler D, Kren A, Went P, Derksen PWB, Berns A, Jonkers J, Christofori G. NCAM-induced focal adhesion assembly: A functional switch upon loss of E-cadherin Embo Journal. 27: 2603-2615. PMID 18772882 DOI: 10.1038/emboj.2008.178  0.105
2007 Liao CP, Zhong C, Saribekyan G, Bading J, Park R, Conti PS, Moats R, Berns A, Shi W, Zhou Z, Nikitin AY, Roy-Burman P. Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. Cancer Research. 67: 7525-33. PMID 17671224 DOI: 10.1158/0008-5472.Can-07-0668  0.105
2009 Uren AG, Mikkers H, Kool J, van der Weyden L, Lund AH, Wilson CH, Rance R, Jonkers J, van Lohuizen M, Berns A, Adams DJ. A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites. Nature Protocols. 4: 789-98. PMID 19528954 DOI: 10.1038/Nprot.2009.64  0.103
2004 Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, et al. The European dimension for the mouse genome mutagenesis program. Nature Genetics. 36: 925-7. PMID 15340424 DOI: 10.1038/Ng0904-925  0.103
1995 Berns AJ, Clift S, Cohen LK, Donehower RC, Dranoff G, Hauda KM, Jaffee EM, Lazenby AJ, Levitsky HI, Marshall FF. Phase I study of non-replicating autologous tumor cell injections using cells prepared with or without GM-CSF gene transduction in patients with metastatic renal cell carcinoma. Human Gene Therapy. 6: 347-68. PMID 7779918 DOI: 10.1089/Hum.1995.6.3-347  0.102
2009 Kool J, Berns A. High-throughput insertional mutagenesis screens in mice to identify oncogenic networks Nature Reviews Cancer. 9: 389-399. PMID 19461666  0.102
1980 Berns AJ, Lai MH, Bosselman RA, McKennett MA, Bacheler LT, Fan H, Maandag EC, van der Putten HV, Verma IM. Molecular cloning of unintegrated and a portion of integrated moloney murine leukemia viral DNA in bacteriophage lambda. Journal of Virology. 36: 254-63. PMID 6255210 DOI: 10.1128/Jvi.36.1.254-263.1980  0.102
2015 Henneman L, van Miltenburg MH, Michalak EM, Braumuller TM, Jaspers JE, Drenth AP, de Korte-Grimmerink R, Gogola E, Szuhai K, Schlicker A, Bin Ali R, Pritchard C, Huijbers IJ, Berns A, Rottenberg S, et al. Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: 8409-14. PMID 26100884 DOI: 10.1073/pnas.1500223112  0.101
2002 Berns A. Senescence: A companion in chemotherapy? Cancer Cell. 1: 309-311. PMID 12086843 DOI: 10.1016/S1535-6108(02)00063-6  0.099
2006 Peeper D, Berns A. Cross-Species Oncogenomics in Cancer Gene Identification Cell. 125: 1230-1233. PMID 16814709 DOI: 10.1016/j.cell.2006.06.018  0.099
2005 Berns A. Stem cells for lung cancer? Cell. 121: 811-813. PMID 15960966 DOI: 10.1016/j.cell.2005.06.004  0.097
2014 de Jong J, Akhtar W, Badhai J, Rust AG, Rad R, Hilkens J, Berns A, van Lohuizen M, Wessels LF, de Ridder J. Chromatin landscapes of retroviral and transposon integration profiles. Plos Genetics. 10: e1004250. PMID 24721906 DOI: 10.1371/journal.pgen.1004250  0.096
1990 Klein JC, Bleeker MJ, Lutgerink JT, van Dijk WJ, Brugghe HF, van den Elst H, van der Marel GA, van Boom JH, Westra JG, Berns AJ. Use of shuttle vectors to study the molecular processing of defined carcinogen-induced DNA damage: mutagenicity of single O4-ethylthymine adducts in HeLa cells. Nucleic Acids Research. 18: 4131-7. PMID 2377457 DOI: 10.1093/nar/18.14.4131  0.094
2011 de Jong J, de Ridder J, van der Weyden L, Sun N, van Uitert M, Berns A, van Lohuizen M, Jonkers J, Adams DJ, Wessels LF. Computational identification of insertional mutagenesis targets for cancer gene discovery. Nucleic Acids Research. 39: e105. PMID 21652642 DOI: 10.1093/Nar/Gkr447  0.091
2013 Kwon MC, Berns A. Mouse models for lung cancer. Molecular Oncology. 7: 165-77. PMID 23481268 DOI: 10.1016/j.molonc.2013.02.010  0.088
2007 Liu X, Holstege H, Van Der Gulden H, Treur-Mulder M, Zevenhoven J, Velds A, Kerkhoven RM, Van Vliet MH, Wessels LFA, Petersen JL, Berns A, Jonkers J. Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer Proceedings of the National Academy of Sciences of the United States of America. 104: 12111-12116. PMID 17626182 DOI: 10.1073/pnas.0702969104  0.084
2003 Meuwissen R, Linn SC, Linnoila RI, Zevenhoven J, Mooi WJ, Berns A. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model Cancer Cell. 4: 181-189. PMID 14522252 DOI: 10.1016/S1535-6108(03)00220-4  0.083
1992 de Wind N, Wagenaar F, Pol J, Kimman T, Berns A. The pseudorabies virus homology of the herpes simplex virus UL21 gene product is a capsid protein which is involved in capsid maturation. Journal of Virology. 66: 7096-7103. DOI: 10.1128/jvi.66.12.7096-7103.1992  0.081
2013 De Ridder J, Kool J, Uren AG, Bot J, De Jong J, Rust AG, Berns A, Van Lohuizen M, Adams DJ, Wessels L, Reinders M. Mutational genomics for cancer pathway discovery Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7986: 35-46. DOI: 10.1007/978-3-642-39159-0-4  0.08
2006 Derksen PWB, Liu X, Saridin F, van der Gulden H, Zevenhoven J, Evers B, van Beijnum JR, Griffioen AW, Vink J, Krimpenfort P, Peterse JL, Cardiff RD, Berns A, Jonkers J. Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis Cancer Cell. 10: 437-449. PMID 17097565 DOI: 10.1016/j.ccr.2006.09.013  0.08
1982 van der Hoorn FA, Hulsebos E, Berns AJ, Bloemers HP. Molecularly cloned c-mos(rat) is biologically active. The Embo Journal. 1: 1313-7. PMID 6327263 DOI: 10.1002/j.1460-2075.1982.tb01316.x  0.079
2014 Berns A, Pandolfi PP. Tumor microenvironment revisited Embo Reports. 15: 458-459. DOI: 10.1002/Embr.201438794  0.075
2009 Kool J, Berns A. High throughput insertional mutagenesis screens in mice to identify oncogenic networks (Nature Reviews Cancer (2009) 9, (389-399)) Nature Reviews Cancer. 9: 604. DOI: 10.1038/nrc2700  0.073
2016 Serresi M, Gargiulo G, Proost N, Siteur B, Cesaroni M, Koppens M, Xie H, Sutherland KD, Hulsman D, Citterio E, Orkin S, Berns A, van Lohuizen M. Correction to Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer [Cancer Cell 29, 17-31, 2016] Cancer Cell. 29: 241. DOI: 10.1016/j.ccell.2016.01.012  0.072
2010 de Vries NA, Bruggeman SW, Hulsman D, de Vries HI, Zevenhoven J, Buckle T, Hamans BC, Leenders WP, Beijnen JH, van Lohuizen M, Berns AJ, van Tellingen O. Rapid and robust transgenic high-grade glioma mouse models for therapy intervention studies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3431-41. PMID 20472681 DOI: 10.1158/1078-0432.Ccr-09-3414  0.072
2008 van Amerongen R, Berns A. Targeted Anticancer Therapies: Mouse Models Help Uncover the Mechanisms of Tumor Escape (DOI:10.1016/j.ccr.2007.12.019) Cancer Cell. 13: 287. DOI: 10.1016/j.ccr.2008.02.012  0.072
1981 Van Beveren C, Goddard JG, Berns AJ, Verma IM. Biogenesis of a transforming gene. Molecular Biology Reports. 7: 163-5. PMID 7254205 DOI: 10.1007/Bf00778748  0.065
1985 Gielkens AL, Van Oirschot JT, Berns AJ. Genome differences among field isolates and vaccine strains of pseudorabies virus. The Journal of General Virology. 66: 69-82. PMID 2981962 DOI: 10.1099/0022-1317-66-1-69  0.064
2016 Malaspina D, Kranz TM, Heguy A, Harroch S, Mazgaj R, Rothman K, Berns A, Hasan S, Antonius D, Goetz R, Lazar M, Chao MV, Gonen O. Prefrontal neuronal integrity predicts symptoms and cognition in schizophrenia and is sensitive to genetic heterogeneity. Schizophrenia Research. PMID 26925801 DOI: 10.1016/J.Schres.2016.02.031  0.061
2013 Berns A, Barbacid M. Mouse models of cancer. Molecular Oncology. 7: 143-5. PMID 23499582 DOI: 10.1016/J.Molonc.2013.02.014  0.061
2015 Rajan A, Berns A, Ringborg U, Celis J, Ponder B, Caldas C, Livingston D, Bristow RG, Hecht TT, Tursz T, van Luenen H, Bono P, Helander T, Seamon K, Smyth JF, et al. Excellent translational research in oncology: A journey towards novel and more effective anti-cancer therapies. Molecular Oncology. PMID 26797050 DOI: 10.1016/J.Molonc.2015.12.007  0.059
1990 van Oirschot JT, Terpstra C, Moormann RJ, Berns AJ, Gielkens AL. Safety of an Aujeszky's disease vaccine based on deletion mutant strain 783 which does not express thymidine kinase and glycoprotein I. The Veterinary Record. 127: 443-6. PMID 2177288  0.058
2014 Bin Ali R, van der Ahé F, Braumuller TM, Pritchard C, Krimpenfort P, Berns A, Huijbers IJ. Improved pregnancy and birth rates with routine application of nonsurgical embryo transfer Transgenic Research. 23: 691-695. PMID 24798251 DOI: 10.1007/s11248-014-9802-3  0.056
1995 Lie-Venema H, Labruyère WT, van Roon MA, de Boer PA, Moorman AF, Berns AJ, Lamers WH. The spatio-temporal control of the expression of glutamine synthetase in the liver is mediated by its 5'-enhancer. The Journal of Biological Chemistry. 270: 28251-6. PMID 7499322 DOI: 10.1074/jbc.270.47.28251  0.056
2009 Uren A, Berns A. Jump-starting cancer gene discovery Nature Biotechnology. 27: 251-252. PMID 19270673 DOI: 10.1038/nbt0309-251  0.055
2015 Gazdar AF, Savage TK, Johnson JE, Berns A, Sage J, Linnoila RI, MacPherson D, McFadden DG, Farago A, Jacks T, Travis WD, Brambilla E. The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 553-64. PMID 25675280 DOI: 10.1097/Jto.0000000000000459  0.053
2010 Dannenberg Jan-Hermen JH, Berns A. Drugging Drug Resistance Cell. 141: 18-20. DOI: 10.1016/j.cell.2010.03.020  0.048
2015 Semenova EA, Nagel R, Berns A. Origins, genetic landscape, and emerging therapies of small cell lung cancer Genes and Development. 29: 1447-1462. DOI: 10.1101/gad.263145.115  0.048
1990 van Oirschot JT, Gielkens AL, Moormann RJ, Berns AJ. Marker vaccines, virus protein-specific antibody assays and the control of Aujeszky's disease. Veterinary Microbiology. 23: 85-101. PMID 2169682 DOI: 10.1016/0378-1135(90)90139-M  0.046
2008 Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, ... ... Berns A, et al. Corrigendum: Pim-1 regulates cardiomyocyte survival downstream of Akt (Nature Medicine (2007) 13, (1467-1475)) Nature Medicine. 14: 350. DOI: 10.1038/Nm0308-350  0.043
2006 Berns A. Cancer biology: Can less be more for p53? Nature. 443: 153-154. PMID 16971934 DOI: 10.1038/443153a  0.042
2010 Berns A. Cancer: The blind spot of p53 Nature. 468: 519-520. PMID 21107421 DOI: 10.1038/468519a  0.036
1991 van Oirschot JT, Moormann RJ, Berns AJ, Gielkens AL. Efficacy of a pseudorabies virus vaccine based on deletion mutant strain 783 that does not express thymidine kinase and glycoprotein I. American Journal of Veterinary Research. 52: 1056-60. PMID 1654033  0.033
2008 Boyle P, Anderson BO, Andersson LC, Ariyaratne Y, Auleley GR, Barbacid M, Bartelink H, Baselga J, Behbehani K, Belardelli F, Berns A, Bishop J, Brawley O, Burns H, Clanton M, et al. Need for global action for cancer control. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 19: 1519-21. PMID 18723552 DOI: 10.1093/Annonc/Mdn426  0.032
2008 Berns A. Kras and Hras - What is the difference? Nature Genetics. 40: 1149-1150. PMID 18818716 DOI: 10.1038/ng1008-1149  0.032
2004 Berns A. Good News for Gene Therapy New England Journal of Medicine. 350: 1679-1680. PMID 15084702 DOI: 10.1056/NEJMcibr040341  0.029
2011 Berns A. Insertional mutagenesis: A powerful tool in cancer research Insertional Mutagenesis Strategies in Cancer Genetics. 1-18. DOI: 10.1007/978-1-4419-7656-7_1  0.025
2005 Berns A. Cancer: Two in one Nature. 436: 787-789. PMID 16094355 DOI: 10.1038/436787a  0.017
2005 Boyle P, Ariyaratne M, Bartelink H, Baselga J, Berns A, Brawley OW, Burns H, Davidov M, Dinshaw KA, Dresler C, Eggermont AM, Gajurel D, Gordina G, Gray N, Kakizoe T, et al. Curbing tobacco's toll starts with the professionals: World No Tobacco Day. Lancet (London, England). 365: 1990-2. PMID 15950704 DOI: 10.1016/S0140-6736(05)66590-7  0.016
2012 McGregor KK, Berns AJ, Owen AJ, Michels SA, Duff D, Bahnsen AJ, Lloyd M. Associations between syntax and the lexicon among children with or without ASD and language impairment. Journal of Autism and Developmental Disorders. 42: 35-47. PMID 21365354 DOI: 10.1007/S10803-011-1210-4  0.016
2006 Boyle P, Yasantha Ariyaratne M, Barrington R, Bartelink H, Bartsch G, Berns A, de Valeriola D, Dinshaw KA, Eggermont AM, Gray N, Kakizoe T, Singh Karki B, Kaslar M, Kerr DJ, Khayat D, et al. Tobacco: deadly in any form or disguise Lancet. 367: 1710-1712. PMID 16731252 DOI: 10.1016/S0140-6736(06)68747-3  0.014
2003 Berns A. Timing will tell Nature. 424: 140-141. PMID 12853941 DOI: 10.1038/424140a  0.01
1989 Berns AJ. [The Nobel Prize in Medicine 1989 for Varmus and Bishop]. Nederlands Tijdschrift Voor Geneeskunde. 133: 2539-40. PMID 2689887  0.01
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