Oscar Vargas-Rodriguez - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Biochemistry

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Awawdeh A, Tapia A, Alshawi SA, Dawodu O, Gaier SA, Specht C, Beaudoin JD, Tharp JM, Vargas-Rodriguez O. Efficient suppression of premature termination codons with alanine by engineered chimeric pyrrolysine tRNAs. Nucleic Acids Research. PMID 39558163 DOI: 10.1093/nar/gkae1048  0.727
2024 Radecki AA, Fantasia-Davis A, Maldonado JS, Mann JW, Sepulveda-Camacho S, Morosky P, Douglas J, Vargas-Rodriguez O. Coexisting bacterial aminoacyl-tRNA synthetase paralogs exhibit distinct phylogenetic backgrounds and functional compatibility with Escherichia coli. Iubmb Life. PMID 39417753 DOI: 10.1002/iub.2920  0.392
2024 Douglas J, Cui H, Perona JJ, Vargas-Rodriguez O, Tyynismaa H, Carreño CA, Ling J, Ribas de Pouplana L, Yang XL, Ibba M, Becker H, Fischer F, Sissler M, Carter CW, Wills PR. AARS Online: A collaborative database on the structure, function, and evolution of the aminoacyl-tRNA synthetases. Iubmb Life. PMID 39247978 DOI: 10.1002/iub.2911  0.758
2024 Schuntermann DB, Jaskolowski M, Reynolds NM, Vargas-Rodriguez O. The central role of transfer RNAs in mistranslation. The Journal of Biological Chemistry. 107679. PMID 39154912 DOI: 10.1016/j.jbc.2024.107679  0.497
2024 Cruz E, Vargas-Rodriguez O. The role of tRNA identity elements in aminoacyl-tRNA editing. Frontiers in Microbiology. 15: 1437528. PMID 39101037 DOI: 10.3389/fmicb.2024.1437528  0.529
2024 Awawdeh A, Radecki AA, Vargas-Rodriguez O. Suppressor tRNAs at the interface of genetic code expansion and medicine. Frontiers in Genetics. 15: 1420331. PMID 38798701 DOI: 10.3389/fgene.2024.1420331  0.314
2024 Thaenert A, Sevostyanova A, Chung CZ, Vargas-Rodriguez O, Melnikov SV, Söll D. Engineered mRNA-ribosome fusions for facile biosynthesis of selenoproteins. Proceedings of the National Academy of Sciences of the United States of America. 121: e2321700121. PMID 38442159 DOI: 10.1073/pnas.2321700121  0.546
2023 Schuntermann DB, Fischer JT, Bile J, Gaier SA, Shelley BA, Awawdeh A, Jahn M, Hoffman KS, Westhof E, Söll D, Clarke CR, Vargas-Rodriguez O. Mistranslation of the genetic code by a new family of bacterial transfer RNAs. The Journal of Biological Chemistry. 104852. PMID 37224963 DOI: 10.1016/j.jbc.2023.104852  0.649
2023 Morosky P, Comyns C, Nunes LGA, Chung CZ, Hoffmann PR, Söll D, Vargas-Rodriguez O, Krahn N. Dual incorporation of non-canonical amino acids enables production of post-translationally modified selenoproteins. Frontiers in Molecular Biosciences. 10: 1096261. PMID 36762212 DOI: 10.3389/fmolb.2023.1096261  0.624
2022 Krahn N, Söll D, Vargas-Rodriguez O. Diversification of aminoacyl-tRNA synthetase activities genomic duplication. Frontiers in Physiology. 13: 983245. PMID 36060688 DOI: 10.3389/fphys.2022.983245  0.528
2022 Prabhakar A, Krahn N, Zhang J, Vargas-Rodriguez O, Krupkin M, Fu Z, Acosta-Reyes FJ, Ge X, Choi J, Crnković A, Ehrenberg M, Puglisi EV, Söll D, Puglisi J. Uncovering translation roadblocks during the development of a synthetic tRNA. Nucleic Acids Research. PMID 35882385 DOI: 10.1093/nar/gkac576  0.629
2022 Zhang H, Gong X, Zhao Q, Mukai T, Vargas-Rodriguez O, Zhang H, Zhang Y, Wassel P, Amikura K, Maupin-Furlow J, Ren Y, Xu X, Wolf YI, Makarova KS, Koonin EV, et al. The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism. Nucleic Acids Research. PMID 35466371 DOI: 10.1093/nar/gkac271  0.638
2021 Vargas-Rodriguez O, Badran AH, Hoffman KS, Chen M, Crnković A, Ding Y, Krieger JR, Westhof E, Söll D, Melnikov S. Bacterial translation machinery for deliberate mistranslation of the genetic code. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34413202 DOI: 10.1073/pnas.2110797118  0.59
2021 Tharp JM, Vargas-Rodriguez O, Schepartz A, Söll D. Genetic Encoding of Three Distinct Noncanonical Amino Acids Using Reprogrammed Initiator and Nonsense Codons. Acs Chemical Biology. PMID 33723984 DOI: 10.1021/acschembio.1c00120  0.782
2020 Vargas-Rodriguez O, Bakhtina M, McGowan D, Abid J, Goto Y, Suga H, Musier-Forsyth K. Human -editing enzyme displays tRNA acceptor stem specificity and relaxed amino acid selectivity. The Journal of Biological Chemistry. PMID 33051185 DOI: 10.1074/jbc.RA120.015981  0.639
2019 Hoffman KS, Vargas-Rodriguez O, Bak DW, Mukai T, Woodward LK, Weerapana E, Söll D, Reynolds NM. A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation. The Journal of Biological Chemistry. PMID 31296657 DOI: 10.1074/Jbc.Ra119.008219  0.621
2019 Crnković A, Vargas-Rodriguez O, Söll D. Plasticity and Constraints of tRNA Aminoacylation Define Directed Evolution of Aminoacyl-tRNA Synthetases. International Journal of Molecular Sciences. 20. PMID 31075874 DOI: 10.3390/Ijms20092294  0.643
2019 Kwok HS, Vargas-Rodriguez O, Melnikov SV, Soll D. Engineered aminoacyl-tRNA synthetases with improved selectivity towards non-canonical amino acids. Acs Chemical Biology. PMID 30933556 DOI: 10.1021/Acschembio.9B00088  0.639
2018 Melnikov SV, Khabibullina NF, Mairhofer E, Vargas-Rodriguez O, Reynolds NM, Micura R, Söll D, Polikanov YS. Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Research. PMID 30520988 DOI: 10.1093/Nar/Gky1211  0.602
2018 Vargas-Rodriguez O, Sevostyanova A, Söll D, Crnković A. Upgrading aminoacyl-tRNA synthetases for genetic code expansion. Current Opinion in Chemical Biology. 46: 115-122. PMID 30059834 DOI: 10.1016/J.Cbpa.2018.07.014  0.665
2018 Vargas-Rodriguez O, Englert M, Merkuryev A, Mukai T, Söll D. Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA and elongation factor SelB. Rna Biology. PMID 29879865 DOI: 10.1080/15476286.2018.1474074  0.645
2018 Song Y, Zhou H, Vo MN, Shi Y, Nawaz MH, Vargas-Rodriguez O, Diedrich JK, Yates JR, Kishi S, Musier-Forsyth K, Schimmel P. Publisher Correction: Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid. Nature Communications. 9: 1113. PMID 29535387 DOI: 10.1038/S41467-018-03594-1  0.642
2018 Crnković A, Vargas-Rodriguez O, Merkuryev A, Söll D. Effects of Heterologous tRNA Modifications on the Production of Proteins Containing Noncanonical Amino Acids. Bioengineering (Basel, Switzerland). 5. PMID 29393901 DOI: 10.3390/Bioengineering5010011  0.593
2018 Kunjapur AM, Stork DA, Kuru E, Vargas-Rodriguez O, Landon M, Söll D, Church GM. Engineering posttranslational proofreading to discriminate nonstandard amino acids. Proceedings of the National Academy of Sciences of the United States of America. PMID 29301968 DOI: 10.1073/Pnas.1715137115  0.664
2017 Song Y, Zhou H, Vo MN, Shi Y, Nawaz MH, Vargas-Rodriguez O, Diedrich JK, Yates JR, Kishi S, Musier-Forsyth K, Schimmel P. Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid. Nature Communications. 8: 2281. PMID 29273753 DOI: 10.1038/S41467-017-02201-Z  0.704
2017 Reynolds NM, Vargas-Rodriguez O, Söll D, Crnković A. The central role of tRNA in genetic code expansion. Biochimica Et Biophysica Acta. PMID 28323071 DOI: 10.1016/J.Bbagen.2017.03.012  0.622
2017 Englert M, Vargas-Rodriguez O, Reynolds NM, Wang YS, Söll D, Umehara T. A genomically modified Escherichia coli strain carrying an orthogonal E. coli histidyl-tRNA synthetase•tRNA(His) pair. Biochimica Et Biophysica Acta. PMID 28288813 DOI: 10.1016/J.Bbagen.2017.03.003  0.747
2016 Mukai T, Vargas-Rodriguez O, Englert M, Tripp HJ, Ivanova NN, Rubin EM, Kyrpides NC, Söll D. Transfer RNAs with novel cloverleaf structures. Nucleic Acids Research. PMID 28076288 DOI: 10.1093/Nar/Gkw898  0.645
2016 Napolitano MG, Landon M, Gregg CJ, Lajoie MJ, Govindarajan L, Mosberg JA, Kuznetsov G, Goodman DB, Vargas-Rodriguez O, Isaacs FJ, Söll D, Church GM. Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 113: E5588-97. PMID 27601680 DOI: 10.1073/Pnas.1605856113  0.647
2015 Liu Z, Vargas-Rodriguez O, Goto Y, Novoa EM, Ribas de Pouplana L, Suga H, Musier-Forsyth K. Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation. Proceedings of the National Academy of Sciences of the United States of America. 112: 6027-32. PMID 25918376 DOI: 10.1073/Pnas.1423664112  0.756
2015 Novoa EM, Vargas-Rodriguez O, Lange S, Goto Y, Suga H, Musier-Forsyth K, Ribas de Pouplana L. Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific. The Journal of Biological Chemistry. 290: 10495-503. PMID 25724653 DOI: 10.1074/Jbc.M115.640060  0.692
2014 Vargas-Rodriguez O, Musier-Forsyth K. Structural biology: Wobble puts RNA on target Nature. 510: 480-481. PMID 24919145 DOI: 10.1038/Nature13502  0.688
2014 Das M, Vargas-Rodriguez O, Goto Y, Suga H, Musier-Forsyth K. Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation. Nucleic Acids Research. 42: 3943-53. PMID 24371276 DOI: 10.1093/Nar/Gkt1332  0.711
2013 Vargas-Rodriguez O, Musier-Forsyth K. Exclusive use of trans-editing domains prevents proline mistranslation Journal of Biological Chemistry. 288: 14391-14399. PMID 23564458 DOI: 10.1074/Jbc.M113.467795  0.671
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