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228 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Stolze SC, Liu N, Wijdeven RH, Tuin AW, van den Nieuwendijk AM, Florea BI, van der Stelt M, van der Marel GA, Neefjes JJ, Overkleeft HS. Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes. Molecular Biosystems. PMID 27138522 DOI: 10.1039/c6mb00257a  0.48
2015 van der Kant R, Jonker CT, Wijdeven RH, Bakker J, Janssen L, Klumperman J, Neefjes J. Characterization of the mammalian CORVET and HOPS complexes and their modular restructuring for endosome specificity. The Journal of Biological Chemistry. PMID 26463206 DOI: 10.1074/jbc.M115.688440  0.48
2015 Wijdeven RH, Jongsma ML, Neefjes J, Berlin I. ER contact sites direct late endosome transport. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 26440125 DOI: 10.1002/bies.201500095  0.48
2015 Berkers CR, de Jong A, Schuurman KG, Linnemann C, Meiring HD, Janssen L, Neefjes JJ, Schumacher TN, Rodenko B, Ovaa H. Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules. Journal of Immunology (Baltimore, Md. : 1950). PMID 26401003 DOI: 10.4049/jimmunol.1402455  0.48
2015 Bentin Toaldo C, Alexi X, Beelen K, Kok M, Hauptmann M, Jansen M, Berns E, Neefjes J, Linn S, Michalides R, Zwart W. Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13. Bmc Cancer. 15: 588. PMID 26272591 DOI: 10.1186/s12885-015-1591-4  0.48
2015 Wijdeven RH, Pang B, van der Zanden SY, Qiao X, Blomen V, Hoogstraat M, Lips EH, Janssen L, Wessels L, Brummelkamp TR, Neefjes J. Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer. Cancer Research. 75: 4176-87. PMID 26260527 DOI: 10.1158/0008-5472.CAN-15-0380  0.48
2015 Scanu T, Spaapen RM, Bakker JM, Pratap CB, Wu LE, Hofland I, Broeks A, Shukla VK, Kumar M, Janssen H, Song JY, Neefjes-Borst EA, Te Riele H, Holden DW, Nath G, ... Neefjes J, et al. Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma. Cell Host & Microbe. 17: 763-74. PMID 26028364 DOI: 10.1016/j.chom.2015.05.002  0.48
2015 Pang B, de Jong J, Qiao X, Wessels LF, Neefjes J. Chemical profiling of the genome with anti-cancer drugs defines target specificities. Nature Chemical Biology. 11: 472-80. PMID 25961671 DOI: 10.1038/nchembio.1811  0.48
2015 Surace L, Lysenko V, Fontana AO, Cecconi V, Janssen H, Bicvic A, Okoniewski M, Pruschy M, Dummer R, Neefjes J, Knuth A, Gupta A, van den Broek M. Complement is a central mediator of radiotherapy-induced tumor-specific immunity and clinical response. Immunity. 42: 767-77. PMID 25888260 DOI: 10.1016/j.immuni.2015.03.009  0.48
2015 van Luijn MM, Kreft KL, Jongsma ML, Mes SW, Wierenga-Wolf AF, van Meurs M, Melief MJ, der Kant Rv, Janssen L, Janssen H, Tan R, Priatel JJ, Neefjes J, Laman JD, Hintzen RQ. Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis Brain : a Journal of Neurology. 138: 1531-1547. PMID 25823473 DOI: 10.1093/brain/awv080  0.48
2015 Garstka MA, Fish A, Celie PH, Joosten RP, Janssen GM, Berlin I, Hoppes R, Stadnik M, Janssen L, Ovaa H, van Veelen PA, Perrakis A, Neefjes J. The first step of peptide selection in antigen presentation by MHC class I molecules. Proceedings of the National Academy of Sciences of the United States of America. 112: 1505-10. PMID 25605945 DOI: 10.1073/pnas.1416543112  0.48
2015 Jongsma ML, Berlin I, Neefjes J. On the move: organelle dynamics during mitosis. Trends in Cell Biology. 25: 112-24. PMID 25466831 DOI: 10.1016/j.tcb.2014.10.005  0.48
2015 De Wit J, Jorritsma T, Makuch M, Remmerswaal EBM, Klaasse Bos H, Souwer Y, Neefjes J, Ten Berge IJM, Van Ham SM. Human B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures Journal of Allergy and Clinical Immunology. 135: 1053-1060. PMID 25258142 DOI: 10.1016/j.jaci.2014.08.012  0.48
2015 Dohmen AJC, Swartz JE, Van Den Brekel MWM, Willems SM, Spijker R, Neefjes J, Zuur CL. Feasibility of primary tumor culture models and preclinical prediction assays for head and neck cancer: A narrative review Cancers. 7: 1716-1742. DOI: 10.3390/cancers7030858  0.48
2015 van Deventer S, Menendez-Benito V, van Leeuwen F, Neefjes J. N-terminal acetylation and replicative age affect proteasome localization and cell fitness during aging Journal of Cell Science. 128: 109-117. DOI: 10.1242/jcs.157354  0.48
2015 Neefjes J. Expanding the peptidome for immunotherapy Blood. 126: 1154-1156. DOI: 10.1182/blood-2015-07-657130  0.48
2014 Luteijn RD, Hoelen H, Kruse E, van Leeuwen WF, Grootens J, Horst D, Koorengevel M, Drijfhout JW, Kremmer E, Früh K, Neefjes JJ, Killian A, Lebbink RJ, Ressing ME, Wiertz EJ. Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP. Journal of Immunology (Baltimore, Md. : 1950). 193: 1578-89. PMID 25024387 DOI: 10.4049/jimmunol.1400964  0.48
2014 Verbrugge I, Gasparini A, Haynes NM, Hagekyriakou J, Galli M, Stewart TJ, Abrams SI, Yagita H, Verheij M, Johnstone RW, Borst J, Neefjes J. The curative outcome of radioimmunotherapy in a mouse breast cancer model relies on mTOR signaling. Radiation Research. 182: 219-29. PMID 24960417 DOI: 10.1667/RR13511.1  0.48
2014 van Kasteren SI, Overkleeft H, Ovaa H, Neefjes J. Chemical biology of antigen presentation by MHC molecules Current Opinion in Immunology. 26: 21-31. PMID 24556397 DOI: 10.1016/j.coi.2013.10.005  0.48
2014 Van Der Kant R, Neefjes J. Small regulators, major consequences-Ca2+ and cholesterol at the endosome-ER interface Journal of Cell Science. 127: 929-938. PMID 24554437 DOI: 10.1242/jcs.137539  0.48
2014 Neefjes J, van der Kant R. Stuck in traffic: An emerging theme in diseases of the nervous system Trends in Neurosciences. 37: 66-76. PMID 24411104 DOI: 10.1016/j.tins.2013.11.006  0.48
2014 Albers HM, Kuijl C, Bakker J, Hendrickx L, Wekker S, Farhou N, Liu N, Blasco-Moreno B, Scanu T, den Hertog J, Celie P, Ovaa H, Neefjes J. Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection. Acs Chemical Biology. 9: 414-22. PMID 24274083 DOI: 10.1021/cb400421a  0.48
2014 Wijdeven RH, Neefjes J, Ovaa H. How chemistry supports cell biology: The chemical toolbox at your service Trends in Cell Biology. 24: 751-760. DOI: 10.1016/j.tcb.2014.07.002  0.48
2013 Neefjes J, Ovaa H. A peptide's perspective on antigen presentation to the immune system Nature Chemical Biology. 9: 769-775. PMID 24231618 DOI: 10.1038/nchembio.1391  0.48
2013 van der Kant R, Fish A, Janssen L, Janssen H, Krom S, Ho N, Brummelkamp T, Carette J, Rocha N, Neefjes J. Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L. Journal of Cell Science. 126: 3462-74. PMID 23729732 DOI: 10.1242/jcs.129270  0.48
2013 Pang B, Qiao X, Janssen L, Velds A, Groothuis T, Kerkhoven R, Nieuwland M, Ovaa H, Rottenberg S, van Tellingen O, Janssen J, Huijgens P, Zwart W, Neefjes J. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nature Communications. 4: 1908. PMID 23715267 DOI: 10.1038/ncomms2921  0.48
2013 Terweij M, Welsem Tv, Deventer SV, Verzijlbergen KF, Menendez-Benito V, Ontoso D, San-Segundo P, Neefjes J, Leeuwen Fv. Recombination-induced tag exchange (RITE) cassette series to monitor protein dynamics in saccharomyces cerevisiae G3: Genes, Genomes, Genetics. 3: 1261-1272. PMID 23708297 DOI: 10.1534/g3.113.006213  0.48
2013 Ekkebus R, van Kasteren SI, Kulathu Y, Scholten A, Berlin I, Geurink PP, de Jong A, Goerdayal S, Neefjes J, Heck AJ, Komander D, Ovaa H. On terminal alkynes that can react with active-site cysteine nucleophiles in proteases. Journal of the American Chemical Society. 135: 2867-70. PMID 23387960 DOI: 10.1021/ja309802n  0.48
2013 Kuijl C, Pilli M, Alahari SK, Janssen H, Khoo PS, Ervin KE, Calero M, Jonnalagadda S, Scheller RH, Neefjes J, Junutula JR. Rac and Rab GTPases dual effector Nischarin regulates vesicle maturation to facilitate survival of intracellular bacteria. The Embo Journal. 32: 713-27. PMID 23386062 DOI: 10.1038/emboj.2013.10  0.48
2013 Paul P, Neefjes J. Studying MHC class II transport in dendritic cells. Methods in Molecular Biology (Clifton, N.J.). 960: 489-507. PMID 23329509 DOI: 10.1007/978-1-62703-218-6_36  0.48
2013 Jongsma MLM, Neefjes J. Assaying peptide translocation by the peptide transporter TAP Methods in Molecular Biology. 960: 53-65. PMID 23329478 DOI: 10.1007/978-1-62703-218-6_5  0.48
2013 van de Kooij B, Verbrugge I, de Vries E, Gijsen M, Montserrat V, Maas C, Neefjes J, Borst J. Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1. The Journal of Biological Chemistry. 288: 6617-28. PMID 23300075 DOI: 10.1074/jbc.M112.448209  0.48
2013 Neefjes J, Unanue ER. The ever surprising field of antigen presentation Molecular Immunology. 55: 105. PMID 23298870 DOI: 10.1016/j.molimm.2012.11.003  0.48
2013 Menendez-Benito V, Van Deventer SJ, Jimenez-Garcia V, Roy-Luzarraga M, Van Leeuwen F, Neefjes J. Spatiotemporal analysis of organelle and macromolecular complex inheritance Proceedings of the National Academy of Sciences of the United States of America. 110: 175-180. PMID 23248297 DOI: 10.1073/pnas.1207424110  0.48
2013 Garstka MA, Neefjes J. How to target MHC class II into the MIIC compartment Molecular Immunology. 55: 162-165. PMID 23200228 DOI: 10.1016/j.molimm.2012.10.022  0.48
2013 Wijdeven RH, Bakker JM, Paul P, Neefjes J. Exploring genome-wide datasets of MHC class II antigen presentation. Molecular Immunology. 55: 172-4. PMID 23137594 DOI: 10.1016/j.molimm.2012.10.014  0.48
2013 De Leeuw R, Flach K, Toaldo CB, Alexi X, Canisius S, Neefjes J, Michalides R, Zwart W. PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance Oncogene. 32: 3543-3551. PMID 22907427 DOI: 10.1038/onc.2012.361  0.48
2013 Van Der Kant R, Zondervan I, Janssen L, Neefjes J. Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1 Journal of Lipid Research. 54: 2153-2165. DOI: 10.1194/jlr.M037325  0.48
2012 Souwer Y, Griekspoor A, de Wit J, Martinoli C, Zagato E, Janssen H, Jorritsma T, Bar-Ephraïm YE, Rescigno M, Neefjes J, van Ham SM. Selective Infection of Antigen-Specific B Lymphocytes by Salmonella Mediates Bacterial Survival and Systemic Spreading of Infection Plos One. 7. PMID 23209805 DOI: 10.1371/journal.pone.0050667  0.48
2012 Huang S, Hölzel M, Knijnenburg T, Schlicker A, Roepman P, McDermott U, Garnett M, Grernrum W, Sun C, Prahallad A, Groenendijk FH, Mittempergher L, Nijkamp W, Neefjes J, Salazar R, et al. MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling Cell. 151: 937-950. PMID 23178117 DOI: 10.1016/j.cell.2012.10.035  0.48
2012 de Jong A, Merkx R, Berlin I, Rodenko B, Wijdeven RH, El Atmioui D, Yalçin Z, Robson CN, Neefjes JJ, Ovaa H. Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes. Chembiochem : a European Journal of Chemical Biology. 13: 2251-8. PMID 23011887 DOI: 10.1002/cbic.201200497  0.48
2012 Majera D, Kristan KC, Neefjes J, Turk D, Miheli? M. Expression, purification and assembly of soluble multimeric MHC class II-invariant chain complexes Febs Letters. 586: 1318-1324. PMID 22465664 DOI: 10.1016/j.febslet.2012.03.038  0.48
2012 Houtman R, De Leeuw R, Rondaij M, Melchers D, Verwoerd D, Ruijtenbeek R, Martens JWM, Neefjes J, Michalides R. Serine-305 phosphorylation modulates estrogen receptor alpha binding to a coregulator peptide array, with potential application in predicting responses to tamoxifen Molecular Cancer Therapeutics. 11: 805-816. PMID 22319200 DOI: 10.1158/1535-7163.MCT-11-0855  0.48
2012 Hoorn Tv, Paul P, Janssen L, Janssen H, Neefjes J. Dynamics within tetraspanin pairs affect MHC class II expression. Journal of Cell Science. 125: 328-39. PMID 22302999 DOI: 10.1242/jcs.088047  0.48
2012 Spaapen RM, Neefjes J. Immuno-waste exposure and further management Nature Immunology. 13: 109-111. PMID 22261957 DOI: 10.1038/ni.2204  0.48
2012 Uusi-Rauva K, Kyttälä A, Van Der Kant R, Vesa J, Tanhuanpää K, Neefjes J, Olkkonen VM, Jalanko A. Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments Cellular and Molecular Life Sciences. 69: 2075-2089. PMID 22261744 DOI: 10.1007/s00018-011-0913-1  0.48
2012 Neefjes J, Sadaka C. Into the intracellular logistics of cross-presentation Frontiers in Immunology. 3. DOI: 10.3389/fimmu.2012.00031  0.48
2011 Neefjes J, Jongsma ML, Paul P, Bakke O. Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nature Reviews. Immunology. 11: 823-36. PMID 22076556 DOI: 10.1038/nri3084  0.48
2011 Verweij FJ, Van Eijndhoven MAJ, Hopmans ES, Vendrig T, Wurdinger T, Cahir-Mcfarland E, Kieff E, Geerts D, Van Der Kant R, Neefjes J, Middeldorp JM, Pegtel DM. LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation Embo Journal. 30: 2115-2129. PMID 21527913 DOI: 10.1038/emboj.2011.123  0.48
2011 Paul P, van den Hoorn T, Jongsma ML, Bakker MJ, Hengeveld R, Janssen L, Cresswell P, Egan DA, van Ham M, Ten Brinke A, Ovaa H, Beijersbergen RL, Kuijl C, Neefjes J. A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell. 145: 268-83. PMID 21458045 DOI: 10.1016/j.cell.2011.03.023  0.48
2011 Kessler JH, Khan S, Seifert U, Le Gall S, Chow KM, Paschen A, Bres-Vloemans SA, De Ru A, Van Montfoort N, Franken KLMC, Benckhuijsen WE, Brooks JM, Van Hall T, Ray K, Mulder A, ... ... Neefjes J, et al. Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes Nature Immunology. 12: 45-53. PMID 21151101 DOI: 10.1038/ni.1974  0.48
2011 van den Hoorn T, Paul P, Jongsma ML, Neefjes J. Routes to manipulate MHC class II antigen presentation. Current Opinion in Immunology. 23: 88-95. PMID 21112200 DOI: 10.1016/j.coi.2010.11.002  0.48
2011 Kok M, Zwart W, Holm C, Fles R, Hauptmann M, Van'T Veer LJ, Wessels LFA, Neefjes J, Stål O, Linn SC, Landberg G, Michalides R. PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer Breast Cancer Research and Treatment. 125: 1-12. PMID 20213082 DOI: 10.1007/s10549-010-0798-y  0.48
2010 Salomon I, Janssen H, Neefjes J. Mechanical forces used for cell fractionation can create hybrid membrane vesicles International Journal of Biological Sciences. 6: 649-654. PMID 21060726  0.48
2010 Zwart W, Peperzak V, de Vries E, Keller AM, van der Horst G, Veraar EA, Geumann U, Janssen H, Janssen L, Naik SH, Neefjes J, Borst J. The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells. Journal of Cell Science. 123: 3817-27. PMID 20971706 DOI: 10.1242/jcs.068510  0.48
2010 de Wit J, Souwer Y, Jorritsma T, Bos HK, Brinke tA, Neefjes J, Marieke van Ham S. Antigen-specific B cells reactivate an effective cytotoxic T Cell response against phagocytosed Salmonella through cross-presentation Plos One. 5. PMID 20885961 DOI: 10.1371/journal.pone.0013016  0.48
2010 Pang B, Neefjes J. Coupled for cross-presentation in tumor immunotherapy Science Translational Medicine. 2. PMID 20702855 DOI: 10.1126/scitranslmed.3001245  0.48
2010 Zwart W, De Leeuw R, Rondaij M, Neefjes J, Mancini MA, Michalides R. The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen Journal of Cell Science. 123: 1253-1261. PMID 20332105 DOI: 10.1242/jcs.061135  0.48
2010 Verzijlbergen KF, Menendez-Benito V, van Welsem T, van Deventer SJ, Lindstrom DL, Ovaa H, Neefjes J, Gottschling DE, van Leeuwen F. Recombination-induced tag exchange to track old and new proteins. Proceedings of the National Academy of Sciences of the United States of America. 107: 64-8. PMID 20018668 DOI: 10.1073/pnas.0911164107  0.48
2010 van Deventer S, Neefjes J. The immunoproteasome cleans up after inflammation Cell. 142: 517-518. DOI: 10.1016/j.cell.2010.08.002  0.48
2009 Kuijl C, Neefjes J. New insight into the everlasting host-pathogen arms race Nature Immunology. 10: 808-809. PMID 19621040 DOI: 10.1038/ni0809-808  0.48
2009 Rocha N, Kuijl C, Van Der Kant R, Janssen L, Houben D, Janssen H, Zwart W, Neefjes J. Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150Glued and late endosome positioning Journal of Cell Biology. 185: 1209-1225. PMID 19564404 DOI: 10.1083/jcb.200811005  0.48
2009 Pang B, Neijssen J, Qiao X, Janssen L, Janssen H, Lippuner C, Neefjes J. Direct antigen presentation and gap junction mediated cross-presentation during apoptosis Journal of Immunology. 183: 1083-1090. PMID 19553546 DOI: 10.4049/jimmunol.0900861  0.48
2009 Souwer Y, Griekspoor A, Jorritsma T, De Wit J, Janssen H, Neefjes J, Van Ham SM. B cell receptor-mediated internalization of Salmonella: A novel pathway for autonomous B cell activation and antibody production Journal of Immunology. 182: 7473-7481. PMID 19494270 DOI: 10.4049/jimmunol.0802831  0.48
2009 Zwart W, Rondaij M, Jalink K, Sharp ZD, Mancini MA, Neefjes J, Michalides R. Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1 Molecular Endocrinology. 23: 1335-1345. PMID 19477949 DOI: 10.1210/me.2008-0268  0.48
2009 Souwer Y, Chamuleau ME, van de Loosdrecht AA, Tolosa E, Jorritsma T, Muris JJ, Dinnissen-van Poppel MJ, Snel SN, van de Corput L, Ossenkoppele GJ, Meijer CJ, Neefjes JJ, Marieke van Ham S. Detection of aberrant transcription of major histocompatibility complex class II antigen presentation genes in chronic lymphocytic leukaemia identifies HLA-DOA mRNA as a prognostic factor for survival. British Journal of Haematology. 145: 334-43. PMID 19245431 DOI: 10.1111/j.1365-2141.2009.07625.x  0.48
2009 Benlalam H, Jalil A, Hasmim M, Pang B, Tamouza R, Mitterrand M, Godet Y, Lamerant N, Robert C, Avril MF, Neefjes J, Tursz T, Mami-Chouaib F, Kieda C, Chouaib S. Gap junction communication between autologous endothelial and tumor cells induce cross-recognition and elimination by specific CTL Journal of Immunology. 182: 2654-2664. PMID 19234159 DOI: 10.4049/jimmunol.0800815  0.48
2009 Holm C, Kok M, Michalides R, Fles R, Koornstra RHT, Wesseling J, Hauptmann M, Neefjes J, Peterse JL, Stål O, Landberg G, Linn SC. Phosphorylation of the oestrogen receptor α at serine 305 and prediction of tamoxifen resistance in breast cancer Journal of Pathology. 217: 372-379. PMID 18991335 DOI: 10.1002/path.2455  0.48
2009 Ovaa H, Kuijl C, Neefjes J. Recent and new targets for small molecule anti-cancer agents Drug Discovery Today: Technologies. 6: e3-e11. DOI: 10.1016/j.ddtec.2010.01.001  0.48
2008 Kuijl C, Tuin AW, Overkleeft H, Neefjes J. Reciprocal chemical genetics for swift lead and target identification Molecular Biosystems. 4: 1001-1008. PMID 19082139 DOI: 10.1039/b803265n  0.48
2008 van den Hoorn T, Neefjes J. Activated pDCs: Open to new antigen-presentation possibilities Nature Immunology. 9: 1208-1210. PMID 18936779 DOI: 10.1038/ni1108-1208  0.48
2008 Hodge JW, Guha C, Neefjes J, Gulley JL. Synergizing radiation therapy and immunotherapy for curing incurable cancers: Opportunities and challenges Oncology. 22: 1064-1070. PMID 18777956  0.48
2008 Koppers-Lalic D, Verweij MC, Lipi?ska AD, Wang Y, Quinten E, Reits EA, Koch J, Loch S, Marcondes Rezende M, Daus F, Bie?kowska-Szewczyk K, Osterrieder N, Mettenleiter TC, Heemskerk MH, Tampé R, ... Neefjes JJ, et al. Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP. Plos Pathogens. 4: e1000080. PMID 18516302 DOI: 10.1371/journal.ppat.1000080  0.48
2008 Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections. Journal of Immunology (Baltimore, Md. : 1950). 180: 1704-12. PMID 18209067  0.48
2008 Rocha N, Neefjes J. MHC class II molecules on the move for successful antigen presentation Embo Journal. 27: 1-5. PMID 18046453 DOI: 10.1038/sj.emboj.7601945  0.48
2007 Kuijl C, Savage NDL, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, Van Den Nieuwendijk R, Van Den Eeden SJF, Geluk A, Poot A, Van Der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff THM, ... Neefjes J, et al. Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1 Nature. 450: 725-730. PMID 18046412 DOI: 10.1038/nature06345  0.48
2007 Berkers CR, van Leeuwen FW, Groothuis TA, Peperzak V, van Tilburg EW, Borst J, Neefjes JJ, Ovaa H. Profiling proteasome activity in tissue with fluorescent probes. Molecular Pharmaceutics. 4: 739-48. PMID 17708652 DOI: 10.1021/mp0700256  0.48
2007 Zwart W, Griekspoor A, Berno V, Lakeman K, Jalink K, Mancini M, Neefjes J, Michalides R. PKA-induced resistance to tamoxifen is associated with an altered orientation of ERα towards co-activator SRC-1 Embo Journal. 26: 3534-3544. PMID 17627277 DOI: 10.1038/sj.emboj.7601791  0.48
2007 Hislop AD, Ressing ME, van Leeuwen D, Pudney VA, Horst D, Koppers-Lalic D, Croft NP, Neefjes JJ, Rickinson AB, Wiertz EJ. A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates. The Journal of Experimental Medicine. 204: 1863-73. PMID 17620360 DOI: 10.1084/jem.20070256  0.48
2007 Zwart W, Griekspoor A, Rondaij M, Verwoerd D, Neefjes J, Michalides R. Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor α Molecular Cancer Therapeutics. 6: 1526-1533. PMID 17513601 DOI: 10.1158/1535-7163.MCT-06-0750  0.48
2007 Ono N, Van der Heijden I, Scheffer GL, Van de Wetering K, Van Deemter E, De Haas M, Boerke A, Gadella BM, De Rooij DG, Neefjes JJ, Groothuis TA, Oomen L, Brocks L, Ishikawa T, Borst P. Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm. The Biochemical Journal. 406: 31-40. PMID 17472575 DOI: 10.1042/BJ20070292  0.48
2007 Neijssen J, Pang B, Neefjes J. Gap junction-mediated intercellular communication in the immune system Progress in Biophysics and Molecular Biology. 94: 207-218. PMID 17467043 DOI: 10.1016/j.pbiomolbio.2007.03.008  0.48
2007 Griekspoor A, Zwart W, Neefjes J, Michalides R. Visualizing the action of steroid hormone receptors in living cells. Nuclear Receptor Signaling. 5: e003. PMID 17464358  0.48
2007 Keller AM, Groothuis TA, Veraar EA, Marsman M, Maillette de Buy Wenniger L, Janssen H, Neefjes J, Borst J. Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 104: 5989-94. PMID 17389361 DOI: 10.1073/pnas.0700946104  0.48
2007 Johansson M, Rocha N, Zwart W, Jordens I, Janssen L, Kuijl C, Olkkonen VM, Neefjes J. Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor βIII spectrin Journal of Cell Biology. 176: 459-471. PMID 17283181 DOI: 10.1083/jcb.200606077  0.48
2007 Menéndez-Benito V, Neefjes J. Autophagy in MHC Class II Presentation: Sampling from Within Immunity. 26: 1-3. PMID 17241953 DOI: 10.1016/j.immuni.2007.01.005  0.48
2006 Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, et al. A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chemistry & Biology. 13: 1217-26. PMID 17114003 DOI: 10.1016/j.chembiol.2006.09.013  0.48
2006 Elliott T, Neefjes J. The Complex Route to MHC Class I-Peptide Complexes Cell. 127: 249-251. PMID 17055423 DOI: 10.1016/j.cell.2006.10.001  0.48
2006 Jordens I, Westbroek W, Marsman M, Rocha N, Mommaas M, Huizing M, Lambert J, Naeyaert JM, Neefjes J. Rab7 and Rab27a control two motor protein activities involved in melanosomal transport Pigment Cell Research. 19: 412-423. PMID 16965270 DOI: 10.1111/j.1600-0749.2006.00329.x  0.48
2006 Qian SB, Reits E, Neefjes J, Deslich JM, Bennink JR, Yewdell JW. Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products Journal of Immunology. 177: 227-233. PMID 16785518  0.48
2006 Bergink S, Salomons FA, Hoogstraten D, Groothuis TAM, De Waard H, Wu J, Yuan L, Citterio E, Houtsmuller AB, Neefjes J, Hoeijmakers JHJ, Vermeulen W, Dantuma NP. DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A Genes and Development. 20: 1343-1352. PMID 16702407 DOI: 10.1101/gad.373706  0.48
2006 Reits EA, Hodge JW, Herberts CA, Groothuis TA, Chakraborty M, Wansley EK, Camphausen K, Luiten RM, de Ru AH, Neijssen J, Griekspoor A, Mesman E, Verreck FA, Spits H, Schlom J, ... ... Neefjes JJ, et al. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. The Journal of Experimental Medicine. 203: 1259-71. PMID 16636135 DOI: 10.1084/jem.20052494  0.48
2006 Marsman M, Jordens I, Rocha N, Kuijl C, Janssen L, Neefjes J. A splice variant of RILP induces lysosomal clustering independent of dynein recruitment Biochemical and Biophysical Research Communications. 344: 747-756. PMID 16631113 DOI: 10.1016/j.bbrc.2006.03.178  0.48
2006 Dantuma NP, Groothuis TAM, Salomons FA, Neefjes J. A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling Journal of Cell Biology. 173: 19-26. PMID 16606690 DOI: 10.1083/jcb.200510071  0.48
2006 Groothuis T, Neefjes J. The ins and outs of intracellular peptides and antigen presentation by MHC class I molecules Current Topics in Microbiology and Immunology. 300: 127-148. PMID 16573239  0.48
2006 Herberts CA, Neijssen JJ, de Haan J, Janssen L, Drijfhout JW, Reits EA, Neefjes JJ. Cutting edge: HLA-B27 acquires many N-terminal dibasic peptides: coupling cytosolic peptide stability to antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 176: 2697-701. PMID 16493024  0.48
2006 Groothuis TAM, Dantuma NP, Neefjes J, Salomons FA. Ubiquitin crosstalk connecting cellular processes Cell Division. 1. DOI: 10.1186/1747-1028-1-21  0.48
2005 Hernández-Muñoz I, Taghavi P, Kuijl C, Neefjes J, Van Lohuizen M. Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1 Molecular and Cellular Biology. 25: 11047-11058. PMID 16314526 DOI: 10.1128/MCB.25.24.11047-11058.2005  0.48
2005 Groothuis TAM, Neefjes J. The many roads to cross-presentation Journal of Experimental Medicine. 202: 1313-1318. PMID 16287713 DOI: 10.1084/jem.20051379  0.48
2005 Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 175: 6605-14. PMID 16272315  0.48
2005 Jordens I, Marsman M, Kuijl C, Neefjes J. Rab proteins, connecting transport and vesicle fusion Traffic. 6: 1070-1077. PMID 16262719 DOI: 10.1111/j.1600-0854.2005.00336.x  0.48
2005 Groothuis TA, Griekspoor AC, Neijssen JJ, Herberts CA, Neefjes JJ. MHC class I alleles and their exploration of the antigen-processing machinery. Immunological Reviews. 207: 60-76. PMID 16181327 DOI: 10.1111/j.0105-2896.2005.00305.x  0.48
2005 Kuipers HF, Biesta PJ, Groothuis TA, Neefjes JJ, Mommaas AM, van den Elsen PJ. Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains. Human Immunology. 66: 653-65. PMID 15993711 DOI: 10.1016/j.humimm.2005.04.004  0.48
2005 Fernandez-Borja M, Janssen L, Verwoerd D, Hordijk P, Neefjes J. RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1 Journal of Cell Science. 118: 2661-2670. PMID 15944396 DOI: 10.1242/jcs.02384  0.48
2005 Griekspoor A, Zwart W, Neefjes J. Presenting antigen presentation in living cells using biophysical techniques Current Opinion in Microbiology. 8: 338-343. PMID 15939359 DOI: 10.1016/j.mib.2005.04.007  0.48
2005 De Almeida SF, Carvalho IF, Cardoso CS, Cordeiro JV, Azevedo JE, Neefjes J, De Sousa M. HFE cross-talks with the MHC class I antigen presentation pathway Blood. 106: 971-977. PMID 15840699 DOI: 10.1182/blood-2004-12-4640  0.48
2005 Marsman M, Jordens I, Griekspoor A, Neefjes J. Chaperoning antigen presentation by MHC class II molecules and their role in oncogenesis Advances in Cancer Research. 93: 129-158. PMID 15797446 DOI: 10.1016/S0065-230X(05)93004-2  0.48
2005 Koppers-Lalic D, Reits EAJ, Ressing ME, Lipinska AD, Abele R, Koch J, Rezende MM, Admiraal P, Van Leeuwen D, Bienkowska-Szewczyk K, Mettenleiter TC, Rijsewijk FAM, Tampé R, Neefjes J, Wiertz EJHJ. Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing Proceedings of the National Academy of Sciences of the United States of America. 102: 5144-5149. PMID 15793001 DOI: 10.1073/pnas.0501463102  0.48
2005 Neijssen J, Herberts C, Drijfhout JW, Reits E, Janssen L, Neefjes J. Cross-presentation by intercellular peptide transfer through gap junctions Nature. 434: 83-88. PMID 15744304 DOI: 10.1038/nature03290  0.48
2005 Zwart W, Griekspoor A, Kuijl C, Marsman M, Van Rheenen J, Janssen H, Calafat J, Van Ham M, Janssen L, Van Lith M, Jalink K, Neefjes J. Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape Immunity. 22: 221-233. PMID 15723810 DOI: 10.1016/j.immuni.2005.01.006  0.48
2005 Harding CV, Neefjes J. Antigen processing and recognition. Current Opinion in Immunology. 17: 55-7. PMID 15653311 DOI: 10.1016/j.coi.2004.12.007  0.48
2004 Neefjes J, Groothuis TAM, Dantuma NP. The 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation | Nobelprijs Scheikunde 2004 voor de ontdekking van ubiquitine-gemedieerde eiwitafbraak Nederlands Tijdschrift Voor Geneeskunde. 148: 2579-2582. PMID 15646859  0.48
2004 Michalides R, Griekspoor A, Balkenende A, Verwoerd D, Janssen L, Jalink K, Floore A, Velds A, Van 't Veer L, Neefjes J. Tamoxifen resistance by a conformational arrest of the estrogen receptor α after PKA activation in breast cancer Cancer Cell. 5: 597-605. PMID 15193262 DOI: 10.1016/j.ccr.2004.05.016  0.48
2004 Reits E, Neijssen J, Herberts C, Benckhuijsen W, Janssen L, Drijfhout JW, Neefjes J. A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation Immunity. 20: 495-506. PMID 15084277 DOI: 10.1016/S1074-7613(04)00074-3  0.48
2004 Marsman M, Jordens I, Kuijl C, Janssen L, Neefjes J. Dynein-mediated vesicle transport controls intracellular Salmonella replication Molecular Biology of the Cell. 15: 2954-2964. PMID 15064357 DOI: 10.1091/mbc.E03-08-0614  0.48
2004 Neefjes J, Dantuma NP. Fluorescent probes for proteolysis: Tools for drug discovery Nature Reviews Drug Discovery. 3: 58-69. PMID 14708021  0.48
2003 Yewdell JW, Reits E, Neefjes J. Making sense of mass destruction: Quantitating MHC class I antigen presentation Nature Reviews Immunology. 3: 952-961. PMID 14647477  0.48
2003 Koppers-Lalic D, Rychlowski M, van Leeuwen D, Rijsewijk FA, Ressing ME, Neefjes JJ, Bienkowska-Szewczyk K, Wiertz EJ. Bovine herpesvirus 1 interferes with TAP-dependent peptide transport and intracellular trafficking of MHC class I molecules in human cells. Archives of Virology. 148: 2023-37. PMID 14551822 DOI: 10.1007/s00705-003-0142-5  0.48
2003 Ressing ME, Van Leeuwen D, Verreck FAW, Gomez R, Heemskerk B, Toebes M, Mullen MM, Jardetzky TS, Longnecker R, Schilham MW, Ottenhoff THM, Neefjes J, Schumacher TN, Hutt-Fletcher LM, Wiertz EJHJ. Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition Proceedings of the National Academy of Sciences of the United States of America. 100: 11583-11588. PMID 14504389 DOI: 10.1073/pnas.2034960100  0.48
2003 Reits E, Neefjes J. The immunological synapse: An exclusive zone for directed cell death after specific recognition | De immunologische synaps: Een exclusieve zone voor gerichte celdood na specifieke herkenning Nederlands Tijdschrift Voor Geneeskunde. 147: 1102-1106. PMID 12822518  0.48
2003 van Lith M, van Ham M, Neefjes J. Stable expression of MHC class I heavy chain/HLA-DO complexes at the plasma membrane European Journal of Immunology. 33: 1145-1151. PMID 12731039 DOI: 10.1002/eji.200323472  0.48
2003 Herberts C, Reits E, Neefjes J. Proteases, proteases and proteases for presentation Nature Immunology. 4: 306-308. PMID 12660727 DOI: 10.1038/ni0403-306  0.48
2003 Reits E, Griekspoor A, Neijssen J, Groothuis T, Jalink K, Van Veelen P, Janssen H, Calafat J, Drijfhout JW, Neefjes J. Peptide Diffusion, Protection, and Degradation in Nuclear and Cytoplasmic Compartments before Antigen Presentation by MHC Class I Immunity. 18: 97-108. PMID 12530979 DOI: 10.1016/S1074-7613(02)00511-3  0.48
2002 Van Lith M, Van Ham M, Neefjes J. Novel polymorphisms in HLA-DOA and HLA-DOB in B-cell malignancies Immunogenetics. 54: 591-595. PMID 12439622 DOI: 10.1007/s00251-002-0500-6  0.48
2002 Reits E, Griekspoor A, Neefjes J. Herpes viral proteins manipulating the peptide transporter TAP Current Topics in Microbiology and Immunology. 269: 75-83. PMID 12224517  0.48
2002 Grommé M, Neefjes J. Antigen degradation or presentation by MHC class I molecules via classical and non-classical pathways Molecular Immunology. 39: 181-202. PMID 12200050 DOI: 10.1016/S0161-5890(02)00101-3  0.48
2002 Villalba M, Bi K, Hu J, Altman Y, Bushway P, Reits E, Neefjes J, Baier G, Abraham RT, Altman A. Translocation of PKCθ in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C Journal of Cell Biology. 157: 253-263. PMID 11956228 DOI: 10.1083/jcb.200201097  0.48
2001 Neefjes J. Determining protein transport to the plasma membrane Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 15.4. PMID 18228331  0.48
2001 Roucard C, Thomas C, Pasquier MA, Trowsdale J, Sotto JJ, Neefjes J, Van Ham M. In vivo and in vitro modulation of HLA-DM and HLA-DO is induced by B lymphocyte activation Journal of Immunology. 167: 6849-6858. PMID 11739502  0.48
2001 Schüller S, Neefjes J, Ottenhoff T, Thole J, Young D. Coronin is involved in uptake of Mycobacterium bovis BCG in human macrophages but not in phagosome maintenance Cellular Microbiology. 3: 785-793. PMID 11736991 DOI: 10.1046/j.1462-5822.2001.00155.x  0.48
2001 Jordens I, Fernandez-Borja M, Marsman M, Dusseljee S, Janssen L, Calafat J, Janssen H, Wubbolts R, Neefjes J. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors Current Biology. 11: 1680-1685. PMID 11696325 DOI: 10.1016/S0960-9822(01)00531-0  0.48
2001 Koppers-Lalic D, Rijsewijk FAM, Verschuren SBE, van Gaans-van den Brink JAM, Neisig A, Ressing ME, Neefjes J, Wiertz EJHJ. The UL41-encoded virion host shutoff (vhs) protein and vhs-independent mechanisms are responsible for down-regulation of MHC class I molecules by bovine herpesvirus 1 Journal of General Virology. 82: 2071-2081. PMID 11514716  0.48
2001 Knuehl C, Spee P, Ruppert T, Kuckelkorn U, Henklein P, Neefjes J, Kloetzel PM. The murine cytomegalovirus pp89 immunodominant H-2Ld epitope is generated and translocated into the endoplasmic reticulum as an 11-mer precursor peptide Journal of Immunology. 167: 1515-1521. PMID 11466372  0.48
2001 Van Lith M, Van Ham M, Griekspoor A, Tjin E, Verwoerd D, Calafat J, Janssen H, Reits E, Pastoors L, Neefjes J. Regulation of MHC class II antigen presentation by sorting of recycling HLA-DM/DO and class II within the multivesicular body Journal of Immunology. 167: 884-892. PMID 11441095  0.48
2001 De Leeuw HPJC, Fernandez-Borja M, Reits EAJ, De Wit TR, Wijers-Koster PM, Hordijk PL, Neefjes J, Van Mourik JA, Voorberg J. Small GTP-binding protein Ral modulates regulated exocytosis of von Willebrand factor by endothelial cells Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 899-904. PMID 11397694  0.48
2001 Reits EA, Neefjes JJ. From fixed to FRAP: measuring protein mobility and activity in living cells. Nature Cell Biology. 3: E145-7. PMID 11389456 DOI: 10.1038/35078615  0.48
2001 Neisig A, Neefjes J. Application of one-dimensional isoelectric focusing to separate different major histocompatibility complex class I alleles and determine their allelic interactions with transporter associated with antigen processing (TAP) Methods in Molecular Biology (Clifton, N.J.). 156: 153-163. PMID 11068757  0.48
2000 Reits EAJ, Griekspoor AC, Neefjes J. How does TAP pump peptides? Insights from DNA repair and traffic ATPases Immunology Today. 21: 598-600. PMID 11114418 DOI: 10.1016/S0167-5699(00)01720-5  0.48
2000 Van Ham M, Van Lith M, Griekspoor A, Neefjes J. What to do with HLA-DO? Immunogenetics. 51: 765-770. PMID 10970090 DOI: 10.1007/s002510000208  0.48
2000 Koopmann JO, Albring J, Hüter E, Bulbuc N, Spee P, Neefjes J, Hämmerling GJ, Momburg F. Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel Immunity. 13: 117-127. PMID 10933400  0.48
2000 Singh-Jasuja H, Toes REM, Spee P, Münz C, Hilf N, Schoenberger SP, Ricciardi-Castagnoli P, Neefjes J, Rammensee HG, Arnold-Schild D, Schild H. Cross-presentation of glycoprotein 96-associated antigens: On major histocompatibility complex class I molecules requires receptor-mediated endocytosis Journal of Experimental Medicine. 191: 1965-1974. PMID 10839811 DOI: 10.1084/jem.191.11.1965  0.48
2000 Reits EAJ, Vos JC, Grammé M, Neefjes J. The major substrates for TAP in vivo are derived from newly synthesized proteins Nature. 404: 774-778. PMID 10783892 DOI: 10.1038/35008103  0.48
2000 Van Marieke H, Van Lith M, Lillemeier B, Tjin E, Grüneberg U, Rahman D, Pastoors L, Van Meijgaarden K, Roucard C, Trowsdale J, Ottenhoff T, Pappin D, Neefjes J. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO Journal of Experimental Medicine. 191: 1127-1135. PMID 10748231 DOI: 10.1084/jem.191.7.1127  0.48
2000 Vos JC, Reits EAJ, Wojcik-Jacobs E, Neefjes J. Head-head/tail-tail relative orientation of the pore-forming domains of the heterodimeric ABC transporter TAP Current Biology. 10: 1-7. PMID 10660295 DOI: 10.1016/S0960-9822(99)00257-2  0.48
2000 Beekman NJ, van Veelen PA, van Hall T, Neisig A, Sijts A, Camps M, Kloetzel PM, Neefjes JJ, Melief CJ, Ossendorp F. Abrogation of CTL epitope processing by single amino acid substitution flanking the C-terminal proteasome cleavage site. Journal of Immunology (Baltimore, Md. : 1950). 164: 1898-905. PMID 10657639  0.48
1999 Wubbolts R, Neefjes J. Intracellular transport and peptide loading of MHC class II molecules: Regulation by chaperones and motors Immunological Reviews. 172: 189-208. PMID 10631947  0.48
1999 Potter PK, Copier J, Sacks SH, Calafat J, Janssen H, Neefjes JJ, Kelly AP. Accurate intracellular localization of HLA-DM requires correct spacing of a cytoplasmic YTPL targeting motif relative to the transmembrane domain. European Journal of Immunology. 29: 3936-44. PMID 10602001 DOI: 10.1002/(SICI)1521-4141(199912)29:12<3936::AID-IMMU3936>3.0.CO;2-K  0.48
1999 Vos JC, Spee P, Momburg F, Neefjes J. Membrane topology and dimerization of the two subunits of the transporter associated with antigen processing reveal a three-domain structure Journal of Immunology. 163: 6679-6685. PMID 10586064  0.48
1999 Andersen MH, Bonfill JE, Neisig A, Arsequell G, Søndergaard I, Neefjes J, Zeuthen J, Elliott T, Haurum JS. Phosphorylated peptides can be transported by TAP molecules, presented by class I MHC molecules, and recognized by phosphopeptide-specific CTL Journal of Immunology. 163: 3812-3818. PMID 10490979  0.48
1999 Grommé M, Uytdehaag FGCM, Janssen H, Calafat J, Van Binnendijk RS, Kenter MJH, Tulp A, Verwoerd D, Neefjes J. Recycling MHC class I molecules and endosomal peptide loading Proceedings of the National Academy of Sciences of the United States of America. 96: 10326-10331. PMID 10468607 DOI: 10.1073/pnas.96.18.10326  0.48
1999 Spee P, Subjeck J, Neefjes J. Identification of novel peptide binding proteins in the endoplasmic reticulum: ERp72, calnexin, and grp170 Biochemistry. 38: 10559-10566. PMID 10441153 DOI: 10.1021/bi990321r  0.48
1999 Haurum JS, Høier IB, Arsequell G, Neisig A, Valencia G, Zeuthen J, Neefjes J, Elliott T. Presentation of cytosolic glycosylated peptides by human class I major histocompatibility complex molecules in vivo Journal of Experimental Medicine. 190: 145-150. PMID 10429679 DOI: 10.1084/jem.190.1.145  0.48
1999 Neefjes J. CIIV, MIIC and other compartments for MHC class II loading European Journal of Immunology. 29: 1421-1425. PMID 10359095 DOI: 10.1002/(SICI)1521-4141(199905)29:05<1421::AID-IMMU1421>3.0.CO;2-C  0.48
1999 Tulp A, Verwoerd D, Neefjes J. Lectin-induced retardation of subcellular organelles during preparative density gradient electrophoresis: Selective purification of plasma membranes Electrophoresis. 20: 438-444. PMID 10217149  0.48
1999 Tulp A, Verwoerd D, Neefjes J. Electromigration for separations of protein complexes Journal of Chromatography B: Biomedical Sciences and Applications. 722: 141-151. PMID 10068138 DOI: 10.1016/S0378-4347(98)00504-0  0.48
1999 Wubbolts R, Fernandez-Borja M, Jordens I, Reits E, Dusseljee S, Echeverri C, Vallee RB, Neefjes J. Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments. Journal of Cell Science. 112: 785-95. PMID 10036229  0.48
1999 Fernandez-Borja M, Wubbolts R, Calafat J, Janssen H, Divecha N, Dusseljee S, Neefjes J. Multivesicular body morphogenesis requires phosphatidylinositol 3-kinase activity Current Biology. 9: 55-58. PMID 9889123 DOI: 10.1016/S0960-9822(99)80048-7  0.48
1998 Vierboom MP, Feltkamp MC, Neisig A, Drijfhout JW, ter Schegget J, Neefjes JJ, Melief CJ, Kast WM. Peptide vaccination with an anchor-replaced CTL epitope protects against human papillomavirus type 16-induced tumors expressing the wild-type epitope. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 399-408. PMID 9807734  0.48
1998 Tulp A, Fernandez-Borja M, Verwoerd D, Neefjes J. High-resolution density gradient electrophoresis of subcellular organelles and proteins under nondenaturing conditions Electrophoresis. 19: 1288-1293. PMID 9694267 DOI: 10.1002/elps.1150190812  0.48
1998 Dusseljee S, Wubbolts R, Verwoerd D, Tulp A, Janssen H, Calafat J, Neefjes J. Removal and degradation of the free MHC class II β chain in the endoplasmic reticulum requires proteasomes and is accelerated by BFA Journal of Cell Science. 111: 2217-2226. PMID 9664043  0.48
1998 Tulp A, Verwoerd D, Benham A, Jalink K, Sier C, Neefjes J. High performance density gradient electrophoresis of subcellular organelles, protein complexes and proteins Electrophoresis. 19: 1171-1178. PMID 9662180 DOI: 10.1002/elps.1150190718  0.48
1998 Benham AM, Grommé M, Neefjes J. Allelic differences in the relationship between proteasome activity and MHC class I peptide loading Journal of Immunology. 161: 83-89. PMID 9647210  0.48
1998 Neisig A, Melief CJM, Neefjes J. Reduced cell surface expression of HLA-C molecules correlates with restricted peptide binding and stable TAP interaction Journal of Immunology. 160: 171-179. PMID 9551969  0.48
1997 Benham AM, Neefjes JJ. Proteasome activity limits the assembly of MHC class I molecules after IFN-gamma stimulation. Journal of Immunology (Baltimore, Md. : 1950). 159: 5896-904. PMID 9550386  0.48
1997 Tulp A, Verwoerd D, Benham A, Neefjes J. High-resolution density gradient electrophoresis of proteins and subcellular organelles Electrophoresis. 18: 2509-2515. PMID 9527478 DOI: 10.1002/elps.1150181404  0.48
1997 Koppelman B, Neefjes JJ, de Vries JE, de Waal Malefyt R. Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling. Immunity. 7: 861-71. PMID 9430231 DOI: 10.1016/S1074-7613(00)80404-5  0.48
1997 Van Ham SM, Tjin EPM, Lillemeier BF, Grüneberg U, Van Meijgaarden KE, Pastoors L, Verwoerd D, Tulp A, Canas B, Rahman D, Ottenhoff THM, Pappin DJC, Trowsdale J, Neefjes J. HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading Current Biology. 7: 950-957. PMID 9382849  0.48
1997 Spee P, Neefjes J. TAP-translocated peptides specifically bind proteins in the endoplasmic reticulum, including gp96, protein disulfide isomerase and calreticulin European Journal of Immunology. 27: 2441-2449. PMID 9341791 DOI: 10.1002/eji.1830270944  0.48
1997 Tan MC, Mommaas AM, Drijfhout JW, Jordens R, Onderwater JJ, Verwoerd D, Mulder AA, van der Heiden AN, Scheidegger D, Oomen LC, Ottenhoff TH, Tulp A, Neefjes JJ, Koning F. Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells. European Journal of Immunology. 27: 2426-35. PMID 9341789 DOI: 10.1002/eji.1830270942  0.48
1997 Reits EAJ, Benham AM, Plougastel B, Neefjes J, Trowsdale J. Dynamics of proteasome distribution in living cells Embo Journal. 16: 6087-6094. PMID 9321388 DOI: 10.1093/emboj/16.20.6087  0.48
1997 Khanna R, Burrows SR, Neisig A, Neefjes J, Moss DJ, Silins SL. Hierarchy of Epstein-Barr virus-specific cytotoxic T-cell responses in individuals carrying different subtypes of an HLA allele: Implications for epitope-based antiviral vaccines Journal of Virology. 71: 7429-7435. PMID 9311821  0.48
1997 Tan MC, Mommaas AM, Drijfhout JW, Jordens R, Onderwater JJ, Verwoerd D, Mulder AA, van der Heiden AN, Ottenhoff TH, Cella M, Tulp A, Neefjes JJ, Koning F. Mannose receptor mediated uptake of antigens strongly enhances HLA-class II restricted antigen presentation by cultured dendritic cells. Advances in Experimental Medicine and Biology. 417: 171-4. PMID 9286356  0.48
1997 Grommé M, Van der Valk R, Sliedregt K, Vernie L, Liskamp R, Hämmerling G, Koopmann JO, Momburg F, Neefjes J. The rational design of TAP inhibitors using peptide substrate modifications and peptidomimetics European Journal of Immunology. 27: 898-904. PMID 9130642 DOI: 10.1002/eji.1830270415  0.48
1997 Cerundolo V, Benham A, Braud V, Mukherjee S, Gould K, Macino B, Neefjes J, Townsend A. The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells European Journal of Immunology. 27: 336-341. PMID 9022037 DOI: 10.1002/eji.1830270148  0.48
1997 Wubbolts R, Fernandez-Bona M, Neefjes J. MHC class II molecules: Transport pathways for antigen presentation Trends in Cell Biology. 7: 115-118. DOI: 10.1016/S0962-8924(97)01000-3  0.48
1996 Izquierdo MA, Neefjes JJ, Mathari AE, Flens MJ, Scheffer GL, Scheper RJ. Overexpression of the ABC transporter TAP in multidrug-resistant human cancer cell lines. British Journal of Cancer. 74: 1961-7. PMID 8980397  0.48
1996 Fernandez-Borja M, Neefjes JJ. How cells instruct the immune system to carry out their elimination. Biochemical Society Transactions. 24: 1039-43. PMID 8968508  0.48
1996 Neefjes JJ. Antigen presentation by MHC class I and II molecules. Immunobiology. 195: 456-60. PMID 8933150 DOI: 10.1016/S0171-2985(96)80015-5  0.48
1996 Volkmann A, Neefjes J, Stockinger B. A conditionally immortalized dendritic cell line which differentiates in contact with T cells or T cell-derived cytokines European Journal of Immunology. 26: 2565-2572. PMID 8921940 DOI: 10.1002/eji.1830261105  0.48
1996 Wubbolts R, Fernandez-Borja M, Oomen L, Verwoerd D, Janssen H, Calafat J, Tulp A, Dusseljee S, Neefjes J. Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface Journal of Cell Biology. 135: 611-622. PMID 8909537 DOI: 10.1083/jcb.135.3.611  0.48
1996 Tulp A, Verwoerd D, Fernandez-Borja M, Neefjes J, Hart AAM. High resolution density gradient electrophoresis of cellular organelles Electrophoresis. 17: 173-178. PMID 8907536 DOI: 10.1002/elps.1150170128  0.48
1996 Lewis JW, Neisig A, Neefjes J, Elliott T. Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP. Current Biology : Cb. 6: 873-83. PMID 8805302 DOI: 10.1016/S0960-9822(02)00611-5  0.48
1996 Ossendorp F, Eggers M, Neisig A, Ruppert T, Groettrup M, Sijts A, Mengedé E, Kloetzel PM, Neefjes J, Koszinowski U, Melief C. A single residue exchange within a viral CTL epitope alters proteasome-mediated degradation resulting in lack of antigen presentation Immunity. 5: 115-124. PMID 8769475 DOI: 10.1016/S1074-7613(00)80488-4  0.48
1996 Koopmann JO, Post M, Neefjes JJ, Hämmerling GJ, Momburg F. Translocation of long peptides by transporters associated with antigen processing (TAP). European Journal of Immunology. 26: 1720-8. PMID 8765012 DOI: 10.1002/eji.1830260809  0.48
1996 Brouns GS, de Vries E, Neefjes JJ, Borst J. Assembled pre-B cell receptor complexes are retained in the endoplasmic reticulum by a mechanism that is not selective for the pseudo-light chain. The Journal of Biological Chemistry. 271: 19272-8. PMID 8702609 DOI: 10.1074/jbc.271.32.19272  0.48
1996 Fernandez-Borja M, Verwoerd D, Sanderson F, Aerts H, Trowsdale J, Tulp A, Neefjes J. HLA-DM and MHC class II molecules co-distribute with peptidase-containing lysosomal subcompartments International Immunology. 8: 625-640. PMID 8671650  0.48
1996 Neisig A, Wubbolts R, Zang X, Melief C, Neefjes J. Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing Journal of Immunology. 156: 3196-3206. PMID 8617941  0.48
1996 Sanderson F, Thomas C, Neefjes J, Trowsdale J. Association between HLA-DM and HLA-DR in vivo Immunity. 4: 87-96. PMID 8574855 DOI: 10.1016/S1074-7613(00)80301-5  0.48
1996 Sijts AJAM, Neisig A, Neefjes J, Pamer EG. Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies Journal of Immunology. 156: 685-692. PMID 8543821  0.48
1996 Benham A, Neefjes J. The effect of lactacystin on antigen presentation by MHC Class I molecules Biochemical Society Transactions. 24: 629S.  0.48
1996 Fernandez-Borja M, Neefjes J. How cells instruct the immune system for their suicide Biochemical Society Transactions. 24: 586S.  0.48
1995 Benham AM, Neefjes JJ. Antigen processing by the class I pathway. Biochemical Society Transactions. 23: 664-9. PMID 8566439  0.48
1995 Neisig A, Roelse J, Sijts AJ, Ossendorp F, Feltkamp MC, Kast WM, Melief CJ, Neefjes JJ. Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences. Journal of Immunology (Baltimore, Md. : 1950). 154: 1273-9. PMID 7822796  0.48
1995 Kleijmeer MJ, Ossevoort MA, van Veen CJ, van Hellemond JJ, Neefjes JJ, Kast WM, Melief CJ, Geuze HJ. MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 154: 5715-24. PMID 7751623  0.48
1995 Neefjes J, Gottfried E, Roelse J, Gromme M, Obst R, Hammerling GJ, Momburg F. Analysis of the fine specificity of rat, mouse and human TAP peptide transporters European Journal of Immunology. 25: 1133-1136. PMID 7737286  0.48
1995 Peters PJ, Raposo G, Neefjes JJ, Oorschot V, Leijendekker RL, Geuze HJ, Ploegh HL. Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes. The Journal of Experimental Medicine. 182: 325-34. PMID 7629497 DOI: 10.1084/jem.182.2.325  0.48
1995 Benham A, Tulp A, Neefjes J. Synthesis and assembly of MHC-peptide complexes Immunology Today. 16: 359-362. PMID 7576076 DOI: 10.1016/0167-5699(95)80157-X  0.48
1995 Gournier H, Pascolo S, Siegrist CA, Jehan J, Pérarnau B, Garcia Z, Rose T, Neefjes J, Lemonnier FA. Restriction of self-antigen presentation to cytolytic T lymphocytes by mouse peptide pumps. European Journal of Immunology. 25: 2019-26. PMID 7542602 DOI: 10.1002/eji.1830250733  0.48
1995 Neefjes J. Antigen processing and presentation Research in Immunology. 146: 397-399. DOI: 10.1016/0923-2494(96)81043-1  0.48
1994 Sanderson F, Kleijmeer MJ, Kelly A, Verwoerd D, Tulp A, Neefjes JJ, Geuze HJ, Trowsdale J. Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science (New York, N.Y.). 266: 1566-9. PMID 7985027  0.52
1993 Bijlmakers MJ, Neefjes JJ, Wojcik-Jacobs EH, Ploegh HL. The assembly of H2-Kb class I molecules translated in vitro requires oxidized glutathione and peptide. European Journal of Immunology. 23: 1305-13. PMID 8500526 DOI: 10.1002/eji.1830230618  1
1993 Neefjes JJ, Dierx J, Ploegh HL. The effect of anchor residue modifications on the stability of major histocompatibility complex class I-peptide interactions. European Journal of Immunology. 23: 840-5. PMID 8384560 DOI: 10.1002/eji.1830230411  1
1992 Neefjes JJ, Ploegh HL. Intracellular transport of MHC class II molecules. Immunology Today. 13: 179-84. PMID 1642756 DOI: 10.1016/0167-5699(92)90123-O  1
1992 Faber ED, Oosting R, Neefjes JJ, Ploegh HL, Meijer DK. Distribution and elimination of the glycosidase inhibitors 1-deoxymannojirimycin and N-methyl-1-deoxynojirimycin in the rat in vivo. Pharmaceutical Research. 9: 1442-50. PMID 1475231  1
1992 Neefjes JJ, Smit L, Gehrmann M, Ploegh HL. The fate of the three subunits of major histocompatibility complex class I molecules. European Journal of Immunology. 22: 1609-14. PMID 1318200 DOI: 10.1002/eji.1830220639  0.48
1992 Neefjes JJ, Ploegh HL. Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes. The Embo Journal. 11: 411-6. PMID 1311249  1
1991 Peters PJ, Neefjes JJ, Oorschot V, Ploegh HL, Geuze HJ. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature. 349: 669-76. PMID 1847504 DOI: 10.1038/349669a0  1
1991 Neefjes JJ, Schumacher TN, Ploegh HL. Assembly and intracellular transport of major histocompatibility complex molecules. Current Opinion in Cell Biology. 3: 601-9. PMID 1837724  1
1991 Schumacher TN, De Bruijn ML, Vernie LN, Kast WM, Melief CJ, Neefjes JJ, Ploegh HL. Peptide selection by MHC class I molecules. Nature. 350: 703-6. PMID 1708852 DOI: 10.1038/350703a0  0.48
1990 Neefjes JJ, De Bruijn ML, Boog CJ, Nieland JD, Boes J, Melief CJ, Ploegh HL. N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response. The Journal of Experimental Medicine. 171: 583-8. PMID 2303788  1
1990 Neefjes JJ, Hengeveld T, Tol O, Ploegh HL. Intracellular interactions of transferrin and its receptor during biosynthesis. The Journal of Cell Biology. 111: 1383-92. PMID 2211816  1
1990 Schumacher TN, Heemels MT, Neefjes JJ, Kast WM, Melief CJ, Ploegh HL. Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell. 62: 563-7. PMID 2199065 DOI: 10.1016/0092-8674(90)90020-F  0.48
1990 Ljunggren HG, Stam NJ, Ohlén C, Neefjes JJ, Höglund P, Heemels MT, Bastin J, Schumacher TN, Townsend A, Kärre K. Empty MHC class I molecules come out in the cold. Nature. 346: 476-80. PMID 2198471 DOI: 10.1038/346476a0  0.68
1990 Neefjes JJ, Stollorz V, Peters PJ, Geuze HJ, Ploegh HL. The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route. Cell. 61: 171-83. PMID 2156628  1
1989 Boog CJ, Neefjes JJ, Boes J, Ploegh HL, Melief CJ. Specific immune responses restored by alteration in carbohydrate chains of surface molecules on antigen-presenting cells. European Journal of Immunology. 19: 537-42. PMID 2785048 DOI: 10.1002/eji.1830190319  0.48
1989 Masucci MG, Stam NJ, Torsteinsdottir S, Neefjes JJ, Klein G, Ploegh HL. Allele-specific down-regulation of MHC class I antigens in Burkitt lymphoma lines. Cellular Immunology. 120: 396-400. PMID 2541930  1
1989 Neefjes JJ, Lindhout J, Broxterman HJ, van der Marel GA, van Boom JH, Ploegh HL. Non-carrier-mediated uptake of the mannosidase I inhibitor 1-deoxymannojirimycin by K562 erythroleukemic cells. The Journal of Biological Chemistry. 264: 10271-5. PMID 2524494  1
1989 Doxiadis I, Krumbacher K, Neefjes JJ, Ploegh HL, Grosse-Wilde H. Biochemical evidence that the DLA-B locus codes for a class II determinant expressed on all canine peripheral blood lymphocytes. Experimental and Clinical Immunogenetics. 6: 219-24. PMID 2520676  1
1989 Rotteveel FT, Neefjes JJ, Ploegh HL, Lucas CJ. Influenza virus changes cell-surface glycoproteins including major histocompatibility complex determinants on lymphocytes. Human Immunology. 26: 199-213. PMID 2514159  1
1988 Dobbe LM, Stam NJ, Neefjes JJ, Giphart MJ. Biochemical complexity of serum HLA class I molecules. Immunogenetics. 27: 203-10. PMID 3276619  0.64
1988 Bolscher JG, van der Bijl MM, Neefjes JJ, Hall A, Smets LA, Ploegh HL. Ras (proto)oncogene induces N-linked carbohydrate modification: temporal relationship with induction of invasive potential. The Embo Journal. 7: 3361-8. PMID 3061796  1
1988 Neefjes JJ, Ploegh HL. Allele and locus-specific differences in cell surface expression and the association of HLA class I heavy chain with beta 2-microglobulin: differential effects of inhibition of glycosylation on class I subunit association. European Journal of Immunology. 18: 801-10. PMID 2967765 DOI: 10.1002/eji.1830180522  1
1988 Neefjes JJ, Verkerk JM, Broxterman HJ, van der Marel GA, van Boom JH, Ploegh HL. Recycling glycoproteins do not return to the cis-Golgi. The Journal of Cell Biology. 107: 79-87. PMID 2839522  1
1987 Rein RS, Seemann GH, Neefjes JJ, Hochstenbach FM, Stam NJ, Ploegh HL. Association with beta 2-microglobulin controls the expression of transfected human class I genes. Journal of Immunology (Baltimore, Md. : 1950). 138: 1178-83. PMID 3543123  1
1987 Gruters RA, Neefjes JJ, Tersmette M, de Goede RE, Tulp A, Huisman HG, Miedema F, Ploegh HL. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature. 330: 74-7. PMID 2959866 DOI: 10.1038/330074a0  1
1986 Neefjes JJ, Doxiadis I, Stam NJ, Beckers CJ, Ploegh HL. An analysis of class I antigens of man and other species by one-dimensional IEF and immunoblotting. Immunogenetics. 23: 164-71. PMID 3957414  1
1986 Neefjes JJ, Hensen EJ, de Kroon TI, Ploegh HL. A biochemical characterization of feline MHC products: unusually high expression of class II antigens on peripheral blood lymphocytes. Immunogenetics. 23: 341-7. PMID 3458670  1
1986 Neefjes JJ, Breur-Vriesendorp BS, van Seventer GA, Iványi P, Ploegh HL. An improved biochemical method for the analysis of HLA-class I antigens. Definition of new HLA-class I subtypes. Human Immunology. 16: 169-81. PMID 3087921  1
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