Year |
Citation |
Score |
2020 |
Lu X, Tsutsumi Y, Huang C, Xu W, Byrn SR, Templeton AC, Buevich AV, Amoureux JP, Su Y. Molecular packing of pharmaceuticals analyzed with paramagnetic relaxation enhancement and ultrafast magic angle pinning NMR. Physical Chemistry Chemical Physics : Pccp. PMID 32495810 DOI: 10.1039/D0Cp02049D |
0.317 |
|
2020 |
Lu X, Li M, Huang C, Lowinger MB, Xu W, Yu L, Byrn SR, Templeton AC, Su Y. Atomic-level Drug Substance and Polymer Interaction in Posaconazole Amorphous Solid Dispersion from Solid-State NMR. Molecular Pharmaceutics. PMID 32401529 DOI: 10.1021/Acs.Molpharmaceut.0C00268 |
0.333 |
|
2020 |
Lu X, Huang C, Li M, Skomski D, Xu W, Yu L, Byrn SR, Templeton AC, Su Y. Molecular Mechanism of Crystalline-to-Amorphous Conversion of Pharmaceutical Solids from F Magic Angle Spinning NMR. The Journal of Physical Chemistry. B. PMID 32378905 DOI: 10.1021/Acs.Jpcb.0C02131 |
0.377 |
|
2019 |
Byrn SR, Chen XS, Smith PA. Predictive and Accelerated Formulation Design Using Synchrotron Methods. Aaps Pharmscitech. 20: 176. PMID 31037517 DOI: 10.1208/S12249-019-1375-2 |
0.426 |
|
2019 |
Byrn SR, de Araujo G, Smith P, Benmore C. Continuity of solids between amorphous and crystalline states – insights from synchrotron X-ray pair distribution function (SXPDF) studies Acta Crystallographica Section a Foundations and Advances. 75: a367-a367. DOI: 10.1107/S0108767319096429 |
0.34 |
|
2018 |
de Araujo GLB, Ferreira FF, Bernardes CES, Sato JAP, Gil OM, de Faria DLA, Loebenberg R, Byrn SR, Ghisleni DDM, Bou-Chacra NA, Pinto TJA, Antonio SG, Ferraz HG, Zemlyanov D, Gonçalves DS, et al. A New Thermodynamically Favored Flubendazole/Maleic Acid Binary Crystal Form: Structure, Energetics, and in Silico PBPK Model-Based Investigation Crystal Growth & Design. 18: 2377-2386. DOI: 10.1021/Acs.Cgd.7B01807 |
0.427 |
|
2017 |
Kalra A, Luner P, Taylor LS, Byrn SR, Li T. Gaining Thermodynamic Insight from Distinct Glass Formation Kinetics of Structurally Similar Organic Compounds. Journal of Pharmaceutical Sciences. PMID 28648689 DOI: 10.1016/J.Xphs.2017.06.012 |
0.342 |
|
2017 |
Kalra A, Tishmack P, Lubach JW, Munson E, Taylor LS, Byrn SR, Li T. Impact of Supramolecular Aggregation on the Crystallization Kinetics of Organic Compounds from the Supercooled Liquid State. Molecular Pharmaceutics. PMID 28485947 DOI: 10.1021/Acs.Molpharmaceut.7B00245 |
0.406 |
|
2017 |
de Araujo GL, Benmore CJ, Byrn SR. Local Structure of Ion Pair Interaction in Lapatinib Amorphous Dispersions characterized by Synchrotron X-Ray diffraction and Pair Distribution Function Analysis. Scientific Reports. 7: 46367. PMID 28397829 DOI: 10.1038/Srep46367 |
0.747 |
|
2017 |
Zeller M, de Araujo GL, Parker T, Singh Rai A, Byrn SR. A new solvate of afatinib, a specific inhibitor of the ErbB family of tyrosine kinases. Acta Crystallographica. Section E, Crystallographic Communications. 73: 417-422. PMID 28316823 DOI: 10.1107/S2056989017002626 |
0.736 |
|
2017 |
Nie H, Byrn SR, Zhou QT. Stability of pharmaceutical salts in solid oral dosage forms. Drug Development and Industrial Pharmacy. 1-43. PMID 28276282 DOI: 10.1080/03639045.2017.1304960 |
0.315 |
|
2016 |
Nie H, Xu W, Taylor LS, Marsac PJ, Byrn SR. Crystalline solid dispersion-a strategy to slowdown salt disproportionation in solid state formulations during storage and wet granulation. International Journal of Pharmaceutics. PMID 27979765 DOI: 10.1016/J.Ijpharm.2016.12.014 |
0.351 |
|
2016 |
Nie H, Su Y, Zhang M, Song Y, Leone A, Taylor LS, Marsac PJ, Li T, Byrn SR. Solid-State Spectroscopic Investigation of Molecular Interactions between Clofazimine and Hypromellose Phthalate in Amorphous Solid Dispersions. Molecular Pharmaceutics. PMID 27653759 DOI: 10.1021/Acs.Molpharmaceut.6B00740 |
0.374 |
|
2016 |
Nie H, Xu W, Ren J, Taylor LS, Marsac PJ, John CT, Byrn SR. Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. Molecular Pharmaceutics. PMID 27542728 DOI: 10.1021/Acs.Molpharmaceut.6B00630 |
0.333 |
|
2016 |
Song Y, Zemlyanov D, Chen X, Su Z, Nie H, Lubach JW, Smith D, Byrn S, Pinal R. Acid-base interactions in amorphous solid dispersions of lumefantrine prepared by spray-drying and hot-melt extrusion using X-ray photoelectron spectroscopy. International Journal of Pharmaceutics. PMID 27370910 DOI: 10.1016/J.Ijpharm.2016.06.126 |
0.558 |
|
2016 |
Braun DE, Nartowski KP, Khimyak YZ, Morris KR, Byrn SR, Griesser UJ. Structural Properties, Order-Disorder Phenomena and Phase Stability of Orotic Acid Crystal Forms. Molecular Pharmaceutics. PMID 26741914 DOI: 10.1021/Acs.Molpharmaceut.5B00856 |
0.413 |
|
2016 |
De Araujo GLB, Zeller M, Smith D, Nie H, Byrn SR. Unexpected Single Crystal Growth Induced by a Wire and New Crystalline Structures of Lapatinib Crystal Growth and Design. 16: 6122-6130. DOI: 10.1021/Acs.Cgd.6B01271 |
0.38 |
|
2016 |
Benmore C, Mou Q, Benmore K, Robinson D, Neuefeind J, Ilavsky J, Byrn S, Yarger J. A SAXS-WAXS study of the endothermic transitions in amorphous or supercooled liquid itraconazole Thermochimica Acta. 644: 1-5. DOI: 10.1016/J.Tca.2016.10.004 |
0.305 |
|
2015 |
Song Y, Zemlyanov D, Chen X, Nie H, Su Z, Fang K, Yang X, Smith D, Byrn S, Lubach JW. Acid-Base Interactions of Polystyrene Sulfonic Acid in Amorphous Solid Dispersions Using a Combined UV/FTIR/XPS/ssNMR Study. Molecular Pharmaceutics. PMID 26716395 DOI: 10.1021/Acs.Molpharmaceut.5B00708 |
0.599 |
|
2015 |
Nie H, Mo H, Zhang M, Song Y, Fang K, Taylor LS, Li T, Byrn SR. Investigating the Interaction Pattern and Structural Elements of a Drug-Polymer Complex at the Molecular Level. Molecular Pharmaceutics. 12: 2459-68. PMID 25988812 DOI: 10.1021/Acs.Molpharmaceut.5B00162 |
0.329 |
|
2015 |
Penumetcha SS, Byrn SR, Morris KR. Relaxation Kinetic Study of Eudragit® NM30D Film Based on Complex Modulus Formalism. Aaps Pharmscitech. PMID 25735736 DOI: 10.1208/S12249-015-0289-X |
0.725 |
|
2015 |
Song Y, Yang X, Chen X, Nie H, Byrn S, Lubach JW. Investigation of drug-excipient interactions in lapatinib amorphous solid dispersions using solid-state NMR spectroscopy. Molecular Pharmaceutics. 12: 857-66. PMID 25585133 DOI: 10.1021/Mp500692A |
0.383 |
|
2013 |
Lee J, Boerrigter SX, Jung YW, Byun Y, Yuk SH, Byrn SR, Lee EH. Organic vapor sorption method of isostructural solvates and polymorph of tenofovir disoproxil fumarate. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 50: 253-62. PMID 23872626 DOI: 10.1016/J.Ejps.2013.07.004 |
0.378 |
|
2013 |
Benmore CJ, Weber JK, Tailor AN, Cherry BR, Yarger JL, Mou Q, Weber W, Neuefeind J, Byrn SR. Structural characterization and aging of glassy pharmaceuticals made using acoustic levitation. Journal of Pharmaceutical Sciences. 102: 1290-300. PMID 23381910 DOI: 10.1002/Jps.23464 |
0.405 |
|
2013 |
Weber JKR, Benmore CJ, Tailor AN, Tumber SK, Neuefeind J, Cherry B, Yarger JL, Mou Q, Weber W, Byrn SR. A neutron-X-ray, NMR and calorimetric study of glassy Probucol synthesized using containerless techniques Chemical Physics. 424: 89-92. DOI: 10.1016/J.Chemphys.2013.05.019 |
0.399 |
|
2012 |
Lee EH, Byrn SR, Pinal R. The solution properties of mefenamic acid and a closely related analogue are indistinguishable in polar solvents but significantly different in nonpolar environments. Journal of Pharmaceutical Sciences. 101: 4529-39. PMID 22972701 DOI: 10.1002/Jps.23316 |
0.309 |
|
2012 |
Trasi NS, Byrn SR. Mechanically induced amorphization of drugs: a study of the thermal behavior of cryomilled compounds. Aaps Pharmscitech. 13: 772-84. PMID 22585375 DOI: 10.1208/S12249-012-9801-8 |
0.743 |
|
2012 |
Weber RJ, Benmore CJ, Tumber SK, Tailor AN, Rey CA, Taylor LS, Byrn SR. Acoustic levitation: recent developments and emerging opportunities in biomaterials research. European Biophysics Journal : Ebj. 41: 397-403. PMID 22038123 DOI: 10.1007/S00249-011-0767-3 |
0.311 |
|
2011 |
Ito T, Byrn S, Chen X, Carvajal MT. Thermal insight of mechanically activated bile acid powders. International Journal of Pharmaceutics. 420: 68-75. PMID 21872650 DOI: 10.1016/J.Ijpharm.2011.08.022 |
0.384 |
|
2011 |
Su Z, Luthra S, Krzyzaniak JF, Agra-Kooijman DM, Kumar S, Byrn SR, Shalaev EY. Crystalline, liquid crystalline, and isotropic phases of sodium deoxycholate in water. Journal of Pharmaceutical Sciences. 100: 4836-44. PMID 21721005 DOI: 10.1002/Jps.22690 |
0.563 |
|
2011 |
Trasi NS, Boerrigter SX, Byrn SR, Carvajal TM. Investigating the effect of dehydration conditions on the compactability of glucose. International Journal of Pharmaceutics. 406: 55-61. PMID 21232587 DOI: 10.1016/J.Ijpharm.2010.12.042 |
0.726 |
|
2011 |
Emeje M, Isimi C, Byrn S, Fortunak J, Kunle O, Ofoefule S. Extraction and physicochemical characterization of a new polysaccharide obtained from the fresh fruits of abelmoschus esculentus. Iranian Journal of Pharmaceutical Research. 10: 237-246. DOI: 10.22037/Ijpr.2011.971 |
0.341 |
|
2011 |
Yamauchi M, Lee EH, Otte A, Byrn SR, Carvajal MT. Contrasting the surface and bulk properties of anhydrate and dehydrated hydrate materials Crystal Growth and Design. 11: 692-698. DOI: 10.1021/Cg101098V |
0.329 |
|
2010 |
Engers D, Teng J, Jimenez-Novoa J, Gent P, Hossack S, Campbell C, Thomson J, Ivanisevic I, Templeton A, Byrn S, Newman A. A solid-state approach to enable early development compounds: selection and animal bioavailability studies of an itraconazole amorphous solid dispersion. Journal of Pharmaceutical Sciences. 99: 3901-22. PMID 20602348 DOI: 10.1002/Jps.22233 |
0.332 |
|
2010 |
Lee EH, Byrn SR. Stabilization of metastable flufenamic acid by inclusion of mefenamic acid: solid solution or epilayer? Journal of Pharmaceutical Sciences. 99: 4013-22. PMID 20589947 DOI: 10.1002/Jps.22250 |
0.357 |
|
2010 |
Byrn SR, Zografi G, Chen X. Accelerating proof of concept for small molecule drugs using solid-state chemistry. Journal of Pharmaceutical Sciences. 99: 3665-75. PMID 20589946 DOI: 10.1002/Jps.22215 |
0.447 |
|
2010 |
Li H, Wen H, Stowell JG, Morris KR, Byrn SR. Crystal quality and physical reactivity in the case of flufenamic acid (FFA). Journal of Pharmaceutical Sciences. 99: 3839-48. PMID 20589945 DOI: 10.1002/Jps.22221 |
0.34 |
|
2010 |
Trasi NS, Boerrigter SX, Byrn SR. Investigation of the milling-induced thermal behavior of crystalline and amorphous griseofulvin. Pharmaceutical Research. 27: 1377-89. PMID 20490628 DOI: 10.1007/S11095-010-0129-3 |
0.709 |
|
2010 |
Mao C, Chamarthy SP, Byrn SR, Pinal R. Theoretical and experimental considerations on the enthalpic relaxation of organic glasses using differential scanning calorimetry. The Journal of Physical Chemistry. B. 114: 269-79. PMID 20017467 DOI: 10.1021/Jp906633K |
0.503 |
|
2010 |
Chen X, Stowell JG, Morris KR, Byrn SR. Quantitative study of solid-state acid-base reactions between polymorphs of flufenamic acid and magnesium oxide using X-ray powder diffraction. Journal of Pharmaceutical and Biomedical Analysis. 51: 866-74. PMID 19906502 DOI: 10.1016/J.Jpba.2009.09.021 |
0.476 |
|
2010 |
Atassi F, Mao C, Masadeh AS, Byrn SR. Solid-state characterization of amorphous and mesomorphous calcium ketoprofen. Journal of Pharmaceutical Sciences. 99: 3684-97. PMID 19780126 DOI: 10.1002/Jps.21925 |
0.729 |
|
2010 |
Lee EH, Boerrigter SXM, Byrn SR. Epitaxy of a structurally related compound on the (100) faces of flufenamic acid form i and iii single crystals Crystal Growth and Design. 10: 518-527. DOI: 10.1021/Cg900549H |
0.366 |
|
2010 |
Lee EH, Smith DT, Fanwick PE, Byrn SR. Characterization and anisotropic lattice expansion/contraction of polymorphs of tenofovir disoproxil fumarate Crystal Growth and Design. 10: 2314-2322. DOI: 10.1021/Cg1000667 |
0.375 |
|
2009 |
Emeje M, Nwabunike P, Isimi C, Fortunak J, Mitchell JW, Byrn S, Kunle O, Ofoefule S. Isolation, characterization and formulation properties of a new plant gum obtained from Cissus refescence International Journal of Green Pharmacy. 3: 16-23. DOI: 10.4103/0973-8258.49369 |
0.334 |
|
2008 |
Lee EH, Boerrigter SXM, Rumondor ACF, Chamarthy SP, Byrn SR. Formation and solid-state characterization of a salt-induced metastable polymorph of flufenamic acid Crystal Growth and Design. 8: 91-97. DOI: 10.1021/Cg7008607 |
0.343 |
|
2007 |
Li H, Stowell JG, He X, Morris KR, Byrn SR. Investigations on solid-solid phase transformation of 5-methyl-2-[(4-methyl-2-nitrophenyl)amino]-3-thiophenecarbonitrile. Journal of Pharmaceutical Sciences. 96: 1079-89. PMID 17455331 DOI: 10.1002/Jps.20937 |
0.568 |
|
2007 |
Henck JO, Byrn SR. Designing a molecular delivery system within a preclinical timeframe. Drug Discovery Today. 12: 189-99. PMID 17331883 DOI: 10.1016/J.Drudis.2007.01.006 |
0.311 |
|
2006 |
Mao C, Prasanth Chamarthy S, Byrn SR, Pinal R. A calorimetric method to estimate molecular mobility of amorphous solids at relatively low temperatures. Pharmaceutical Research. 23: 2269-76. PMID 16933097 DOI: 10.1007/S11095-006-9071-9 |
0.495 |
|
2006 |
Atassi F, Byrn SR. General trends in the desolvation behavior of calcium salts. Pharmaceutical Research. 23: 2405-12. PMID 16927185 DOI: 10.1007/S11095-006-9015-4 |
0.661 |
|
2006 |
Lee EH, Byrn SR, Carvajal MT. Additive-induced metastable single crystal of mefenamic acid. Pharmaceutical Research. 23: 2375-80. PMID 16927183 DOI: 10.1007/S11095-006-9045-Y |
0.36 |
|
2006 |
Terakita A, Byrn SR. Structure and physical stability of hydrates and thermotropic mesophase of calcium benzoate. Journal of Pharmaceutical Sciences. 95: 1162-72. PMID 16570305 DOI: 10.1002/Jps.20589 |
0.374 |
|
2006 |
Li H, Stowell JG, Borchardt TB, Byrn SR. Synthesis, conformational polymorphism, and construction of a G-T diagram of 2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile Crystal Growth and Design. 6: 2469-2474. DOI: 10.1021/Cg050608P |
0.305 |
|
2005 |
Qiu Z, Stowell JG, Cao W, Morris KR, Byrn SR, Carvajal MT. Effect of milling and compression on the solid-state Maillard reaction. Journal of Pharmaceutical Sciences. 94: 2568-80. PMID 16200560 DOI: 10.1002/Jps.20448 |
0.563 |
|
2005 |
Qiu Z, Stowell JG, Morris KR, Byrn SR, Pinal R. Kinetic study of the Maillard reaction between metoclopramide hydrochloride and lactose. International Journal of Pharmaceutics. 303: 20-30. PMID 16126356 DOI: 10.1016/J.Ijpharm.2005.06.016 |
0.565 |
|
2005 |
Chen X, Griesser UJ, Te RL, Pfeiffer RR, Morris KR, Stowell JG, Byrn SR. Analysis of the acid-base reaction between solid indomethacin and sodium bicarbonate using infrared spectroscopy, X-ray powder diffraction, and solid-state nuclear magnetic resonance spectroscopy. Journal of Pharmaceutical and Biomedical Analysis. 38: 670-7. PMID 15967295 DOI: 10.1016/J.Jpba.2005.02.017 |
0.76 |
|
2004 |
Davis TD, Peck GE, Stowell JG, Morris KR, Byrn SR. Modeling and monitoring of polymorphic transformations during the drying phase of wet granulation. Pharmaceutical Research. 21: 860-6. PMID 15180346 DOI: 10.1023/B:Pham.0000026440.00508.Cf |
0.561 |
|
2004 |
Grant DJ, Byrn SR. A timely re-examination of drug polymorphism in pharmaceutical development and regulation. Advanced Drug Delivery Reviews. 56: 237-9. PMID 14962580 DOI: 10.1016/J.Addr.2003.12.001 |
0.374 |
|
2003 |
Davis TD, Morris KR, Huang H, Peck GE, Stowell JG, Eisenhauer BJ, Hilden JL, Gibson D, Byrn SR. In situ monitoring of wet granulation using online X-ray powder diffraction. Pharmaceutical Research. 20: 1851-7. PMID 14661932 DOI: 10.1023/B:Pham.0000003385.20030.9A |
0.601 |
|
2003 |
Newman AW, Byrn SR. Solid-state analysis of the active pharmaceutical ingredient in drug products. Drug Discovery Today. 8: 898-905. PMID 14554018 DOI: 10.1016/S1359-6446(03)02832-0 |
0.355 |
|
2003 |
Tishmack PA, Bugay DE, Byrn SR. Solid-state nuclear magnetic resonance spectroscopy--pharmaceutical applications. Journal of Pharmaceutical Sciences. 92: 441-74. PMID 12587108 DOI: 10.1002/Jps.10307 |
0.307 |
|
2003 |
Te RL, Griesser UJ, Morris KR, Byrn SR, Stowell JG. X-ray Diffraction and Solid-State NMR Investigation of the Single-Crystal to Single-Crystal Dehydration of Thiamine Hydrochloride Monohydrate Crystal Growth and Design. 3: 997-1004. DOI: 10.1021/Cg0340749 |
0.771 |
|
2003 |
Reutzel-Edens SM, Bush JK, Magee PA, Stephenson GA, Byrn SR. Anhydrates and Hydrates of Olanzapine: Crystallization, Solid-State Characterization, and Structural Relationships Crystal Growth and Design. 3: 897-907. DOI: 10.1021/Cg034055Z |
0.4 |
|
2002 |
Chen X, Morris KR, Griesser UJ, Byrn SR, Stowell JG. Reactivity differences of indomethacin solid forms with ammonia gas. Journal of the American Chemical Society. 124: 15012-9. PMID 12475345 DOI: 10.1021/Ja017662O |
0.502 |
|
2002 |
Chen X, Li T, Morris KR, Byrn SR. Crystal packing and chemical reactivity of two polymorphs of flufenamic acid with ammonia Molecular Crystals and Liquid Crystals Science and Technology Section a: Molecular Crystals and Liquid Crystals. 381: 121-131. DOI: 10.1080/713738743 |
0.499 |
|
2001 |
Byrn SR, Xu W, Newman AW. Chemical reactivity in solid-state pharmaceuticals: Formulation implications Advanced Drug Delivery Reviews. 48: 115-136. PMID 11325479 DOI: 10.1016/S0169-409X(01)00102-8 |
0.367 |
|
2001 |
He X, Griesser UJ, Stowell JG, Borchardt TB, Byrn SR. Conformational color polymorphism and control of crystallization of 5-methyl-2-[(4-methyl-2-nitrophenyl)amino]-3-thiophenecarbonitrile. Journal of Pharmaceutical Sciences. 90: 371-88. PMID 11170030 DOI: 10.1002/1520-6017(200103)90:3<371::Aid-Jps12>3.0.Co;2-N |
0.594 |
|
2000 |
Guo Y, Byrn SR, Zografi G. Effects of lyophilization on the physical characteristics and chemical stability of amorphous quinapril hydrochloride Pharmaceutical Research. 17: 930-935. PMID 11028937 DOI: 10.1023/A:1007519003070 |
0.316 |
|
2000 |
Morris KR, Stowell JG, Byrn SR, Placette AW, Davis TD, Peck GE. Accelerated fluid bed drying using NIR monitoring and phenomenological modeling. Drug Development and Industrial Pharmacy. 26: 985-8. PMID 10914323 DOI: 10.1081/Ddc-100101326 |
0.572 |
|
2000 |
Guo Y, Byrn SR, Zografi G. Physical characteristics and chemical degradation of amorphous quinapril hydrochloride Journal of Pharmaceutical Sciences. 89: 128-143. PMID 10664545 DOI: 10.1002/(Sici)1520-6017(200001)89:1<128::Aid-Jps13>3.0.Co;2-Z |
0.365 |
|
2000 |
Yu L, Stephenson GA, Mitchell CA, Bunnell CA, Snorek SV, Bowyer JJ, Borchardt TB, Stowell JG, Byrn SR. Thermochemistry and conformational polymorphism of a hexamorphic crystal system Journal of the American Chemical Society. 122: 585-591. DOI: 10.1021/Ja9930622 |
0.376 |
|
1998 |
Chongprasert S, Griesser UJ, Bottorff AT, Williams NA, Byrn SR, Nail SL. Effects of freeze-dry processing conditions on the crystallization of pentamidine isethionate Journal of Pharmaceutical Sciences. 87: 1155-1160. PMID 9724570 DOI: 10.1021/Js970342B |
0.359 |
|
1998 |
Borchardt TB, Stowell JG, Byrn SR. The crystallization of 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile in the presence of structurally similar compounds Molecular Crystals and Liquid Crystals Science and Technology Section a: Molecular Crystals and Liquid Crystals. 313: 271-276. DOI: 10.1080/10587259808044287 |
0.341 |
|
1998 |
Joshi V, Stowell JG, Byrn SR. Solid-state stability of indomethacin solvates Molecular Crystals and Liquid Crystals Science and Technology Section a: Molecular Crystals and Liquid Crystals. 313: 265-270. DOI: 10.1080/10587259808044286 |
0.362 |
|
1998 |
Smith J, MacNamara E, Raftery D, Borchardt T, Byrn S. Application of two-dimensional 13C solid-state NMR to the study of conformational polymorphism Journal of the American Chemical Society. 120: 11710-11713. DOI: 10.1021/Ja980952T |
0.318 |
|
1997 |
Stephenson GA, Stowell JG, Toma PH, Pfeiffer RR, Byrn SR. Solid-state investigations of erythromycin A dihydrate: structure, NMR spectroscopy, and hygroscopicity. Journal of Pharmaceutical Sciences. 86: 1239-44. PMID 9383733 DOI: 10.1021/Js9701667 |
0.404 |
|
1997 |
Xu W, Wahle MC, Stowell JG, Byrn SR. Spirapril hydrochloride hydrate Acta Crystallographica Section C: Crystal Structure Communications. 53: 1917-1919. DOI: 10.1107/S0108270197008287 |
0.315 |
|
1997 |
Shalaev EY, Shalaeva M, Byrn SR, Zografi G. Effects of processing on the solid-state methyl transfer of tetraglycine methyl ester International Journal of Pharmaceutics. 152: 75-88. DOI: 10.1016/S0378-5173(97)00068-9 |
0.345 |
|
1997 |
Stephenson GA, Pfeiffer RR, Byrn SR. Solid-state investigation of the tautomerism of acetohexamide International Journal of Pharmaceutics. 146: 93-99. DOI: 10.1016/S0378-5173(96)04775-8 |
0.373 |
|
1997 |
Shalaev EY, Byrn SR, Zografi G. Single-phase and heterophase solid-state chemical kinetics of thermally induced methyl transfer in tetraglycine methyl ester International Journal of Chemical Kinetics. 29: 339-348. DOI: 10.1002/(Sici)1097-4601(1997)29:5<339::Aid-Kin4>3.0.Co;2-V |
0.336 |
|
1996 |
Stephenson GA, Wozniak TJ, Stowell JG, Byrn SR. Nizatidine, N-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N′- methyl-2-nitro-1,1-ethenediamine Journal of Molecular Structure. 380: 93-100. DOI: 10.1016/0022-2860(96)09216-2 |
0.302 |
|
1995 |
Akers MJ, Milton N, Byrn SR, Nail SL. Glycine Crystallization During Freezing: The Effects of Salt Form, pH, and Ionic Strength Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 1457-1461. PMID 8584480 DOI: 10.1023/A:1016223101872 |
0.384 |
|
1995 |
Saleki‐Gerhardt A, Stoweell JG, Byrn SR, Zografi G. Hydration and dehydration of crystalline and amorphous forms of raffinose Journal of Pharmaceutical Sciences. 84: 318-323. PMID 7616371 DOI: 10.1002/Jps.2600840311 |
0.353 |
|
1994 |
Stephenson GA, Stowell JG, Toma PH, Dorman DE, Greene JR, Byrn SR. Solid-state analysis of polymorphic, isomorphic, and solvated forms of dirithromycin Journal of the American Chemical Society. 116: 5766-5773. DOI: 10.1021/Ja00092A030 |
0.438 |
|
1994 |
Toma PH, Kelley MP, Borchardt TB, Byrn SR, Kahr B. Chromoisomers and polymorphs of 9-phenylacridinium hydrogen sulfate Chemistry of Materials. 6: 1317-1324. DOI: 10.1021/Cm00044A032 |
0.364 |
|
1994 |
Byrn SR, Pfeiffer RR, Stephenson G, Grant DJW, Gleason WB. Solid-state pharmaceutical chemistry Chemistry of Materials. 6: 1148-1158. DOI: 10.1021/Cm00044A013 |
0.39 |
|
1993 |
Saindon PJ, Cauchon NS, Sutton PA, Chang CJ, Peck GE, Byrn SR. Solid-state nuclear magnetic resonance (NMR) spectra of pharmaceutical dosage forms. Pharmaceutical Research. 10: 197-203. PMID 8456065 DOI: 10.1023/A:1018922407786 |
0.323 |
|
1992 |
Stowell JG, Toma PH, Byrn SR. The structure of MK-571 (form I) at 170 K and conformational analysis by molecular modeling Bioorganic and Medicinal Chemistry Letters. 2: 185-190. DOI: 10.1016/S0960-894X(01)80447-9 |
0.324 |
|
1990 |
Martinez H, Byrn SR, Pfeiffer RR. Solid-state chemistry and crystal structure of cefaclor dihydrate. Pharmaceutical Research. 7: 147-53. PMID 2308894 DOI: 10.1023/A:1015824701581 |
0.384 |
|
1988 |
Byrn SR, Sutton PA, Tobias B, Frye J, Main P. The crystal structure, solid-state NMR spectra, and oxygen reactivity of five crystal forms of prednisolone tert-butylacetate Journal of the American Chemical Society. 110: 1609-1614. DOI: 10.1021/Ja00213A039 |
0.388 |
|
1988 |
Mossa JS, Cassady JM, Kozlowski JF, Zennie TM, Antoun MD, Pellechia MG, McKenzie AT, Byrn SR. Novel 6,7-seco-6,11-cyclolabdane diterpenes from cluytia richardiana Tetrahedron Letters. 29: 3627-3630. DOI: 10.1016/S0040-4039(00)82139-5 |
0.306 |
|
1987 |
Sutton PA, Byrn SR. Crystal structure of two crystal forms of 9 alpha-fluorocortisol acetate: variation of the conformation of the A ring of steroids due to crystal packing. Journal of Pharmaceutical Sciences. 76: 253-8. PMID 3585744 DOI: 10.1002/Jps.2600760316 |
0.348 |
|
1987 |
Byrn SR, Perrier P, Lin CT, Martinez H, Pfeiffer RR. The solid-state decarboxylation of the diammonium salt of moxalactam. Pharmaceutical Research. 4: 137-41. PMID 3509137 DOI: 10.1023/A:1016471003785 |
0.392 |
|
1987 |
Byrn SR, Kessler DW. The solid state reactivity of the crystal forms of hydrocortisone esters Tetrahedron. 43: 1335-1343. DOI: 10.1016/S0040-4020(01)90254-6 |
0.357 |
|
1986 |
Byrn SR, McKenzie AT, Hassan MMA, Al-Badr AA. Conformation of glyburide in the solid state and in solution Journal of Pharmaceutical Sciences. 75: 596-600. PMID 3016235 DOI: 10.1002/Jps.2600750615 |
0.341 |
|
1985 |
Byrn SR, Gray G, Pfeiffer RR, Frye J. Analysis of solid-state Carbon-13 NMR spectra of polymorphs (benoxaprofen and nabilone) and pseudopolymorphs (cefazolin). Journal of Pharmaceutical Sciences. 74: 565-8. PMID 2991492 DOI: 10.1002/Jps.2600740516 |
0.348 |
|
1985 |
Byrn SR. Chapter 29. Solid State Organic Chemistry and Drug Stability Annual Reports in Medicinal Chemistry. 20: 287-294. DOI: 10.1016/S0065-7743(08)61055-6 |
0.361 |
|
1982 |
Perrier PR, Byrn SR. Dehydration of glucuronamide hydrate. Confirmation of the predicted influence of crystal packing on dehydration reactions Journal of Organic Chemistry. 47: 4677-4680. DOI: 10.1021/Jo00145A014 |
0.378 |
|
1982 |
Perrier PR, Byrn SR. Influence of crystal packing on the solid-state desolvation of purine and pyrimidine hydrates: Loss of water of crystallization from thymine monohydrate, cytosine monohydrate, 5-nitrouracil monohydrate, and 2′-deoxyadenosine monohydrate Journal of Organic Chemistry. 47: 4671-4676. DOI: 10.1021/Jo00145A013 |
0.375 |
|
1982 |
Lin CT, Perrier P, Clay GG, Sutton PA, Byrn SR. Solid-state photooxidation of 21-cortisol tert-butylacetate to 21-cortisone tert-butylacetate Journal of Organic Chemistry. 47: 2978-2981. DOI: 10.1021/Jo00136A032 |
0.366 |
|
1981 |
Migliaccio GP, Shieh TL, Byrn SR, Hathaway BA, Nichols DE. Comparison of solution conformational preferences for the hallucinogens bufotenin and psilocin using 360-MHz proton NMR spectroscopy. Journal of Medicinal Chemistry. 24: 206-9. PMID 6259355 DOI: 10.1002/Chin.198128356 |
0.311 |
|
1981 |
Morrison H, Izuno C, Byrn S, McKenzie A. PHOTODIMERIZATION OF 1,3-DIMETHYL-5-CHLOROURACIL Photochemistry and Photobiology. 34: 107-109. DOI: 10.1111/J.1751-1097.1981.Tb08969.X |
0.315 |
|
1978 |
Tsai MD, Weintraub HJ, Byrn SR, Chang C, Floss HG. Conformation-reactivity relationship for pyridoxal Schiff's bases. Rates of racemization and alpha-hydrogen exchange of the pyridoxal Schiff's bases of amino acids. Biochemistry. 17: 3183-8. PMID 687574 DOI: 10.1021/Bi00609A002 |
0.303 |
|
1978 |
Tsai MD, Byrn SR, Chang C, Floss HG, Weintraub HJ. Conformational analysis of pyridoxal Schiff's bases. Nuclear magnetic resonance studies of the conformations about the C4-C4', Calpha-Cbeta, and N-Calpha bonds of the pyridoxal Schiff's bases of amino acids. Biochemistry. 17: 3177-82. PMID 687573 DOI: 10.1021/Bi00609A001 |
0.3 |
|
1978 |
Lin CT, Byrn SR. DESOLVATIONS OF SOLVATED ORGANIC CRYSTALS Mol Cryst Liq Cryst. 50: 99-104. DOI: 10.1080/15421407908084418 |
0.333 |
|
1977 |
Stamos IK, Howie GA, Manni PE, Haws WJ, Byrn SR, Cassady JM. Synthesis and structures of dilactones related to anemonin Journal of Organic Chemistry. 42: 1703-1709. DOI: 10.1021/Jo00430A008 |
0.346 |
|
1976 |
Byrn SR, Graber CW, Midland SL. Comparison of the solid and solution conformations of methapyriline, tripelennamine, diphenhydramine, histamine, and choline. The infrared-X-ray method for determination of solution conformations Journal of Organic Chemistry. 41: 2283-2288. PMID 932856 DOI: 10.1021/Jo00875A015 |
0.354 |
|
1976 |
Byrn SR, Lin CT. The effect of crystal packing and defects on desolvation of hydrate crystals of caffeine and L-(-)-1,4-cyclohexadiene-1-alanine [8] Journal of the American Chemical Society. 98: 4004-4005. PMID 932354 DOI: 10.1002/Chin.197638065 |
0.307 |
|
1972 |
Wang AHJ, Missavage RJ, Byrn SR, Paul IC. Crystal and molecular structure of 1-azabicyclo[3.3.3]undecane hydrochloride. Correlation of some molecular dimensions with spectroscopic properties Journal of the American Chemical Society. 94: 7100-7104. DOI: 10.1021/Ja00775A038 |
0.323 |
|
1972 |
Byrn SR, Curtin DY, Paul IC. The X-ray crystal structures of the yellow and white forms of dimethyl 3,6-dichloro-2,5-dihydroxyterephthalate and a study of the conversion of the yellow form to the white form in the solid state Journal of the American Chemical Society. 94: 890-898. DOI: 10.1021/Ja00758A030 |
0.599 |
|
1972 |
BYRN SR, CURTIN DY, PAUL IC. ChemInform Abstract: ROENTGENSTRUKTURANALYSE DER GELBEN UND DER WEISSEN FORM VON 3,6-DICHLOR-2,5-DIHYDROXY-TEREPHTHALSAEUREDIMETHYLESTER UND UNTERSUCHUNG DER UMWANDLUNG DER GELBEN IN DIE WEISSE FORM IM FESTEN ZUSTAND Chemischer Informationsdienst. 3. DOI: 10.1002/Chin.197216104 |
0.525 |
|
1970 |
CURTIN DY, BYRN SR, PENDERGRASS DB. ChemInform Abstract: THERMISCHE UMLAGERUNG VON ARYLAZOTRIBENZOYLMETHANEN IM FESTEN ZUSTAND, UNTERSUCHUNG UEBER DIFFERENTIALTHERMOANALYSE Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197008068 |
0.492 |
|
1970 |
CURTIN DY, BYRN SR. ChemInform Abstract: STRUKTUREN DER GELBEN UND WEISSEN FORM VON 3,6-DICHLOR-2,5-DIHYDROXY-TEREPHTHALSAEUREDIMETHYLESTER IN LOESUNG Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197003034 |
0.527 |
|
1969 |
Curtin DY, Byrn SR, Pendergrass DB. Thermal rearrangement of arylazotribenzoylmethanes in the solid state. Examination with differential thermal analysis Journal of Organic Chemistry. 34: 3345-3349. DOI: 10.1021/Jo01263A028 |
0.533 |
|
1969 |
Curtin DY, Byrn SR. Structures in solution of the yellow and white forms of dimethyl 3,6-dichloro-2,5-dihydroxyterephthalate Journal of the American Chemical Society. 91: 6102-6106. DOI: 10.1021/Ja01050A029 |
0.517 |
|
1969 |
Curtin DY, Byrn SR. Stereoisomerism at the oxygen-carbon single bond due to hydrogen bonding. Structures of the yellow and white crystalline forms of dimethyl 3,6-dichloro-2,5-dihydroxyterephthalate [15] Journal of the American Chemical Society. 91: 1865-1866. DOI: 10.1021/Ja01035A056 |
0.532 |
|
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