George R. Stark - Publications

Affiliations: 
Stanford, ICRF, Cleveland Clinic 
Area:
signal transducers and activators of transcription
Website:
http://www.jbc.org/cgi/ijlink?linkType=FULL&journalCode=jbc&resid=280/11/9753

200 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M. Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models. Cancer Research. PMID 26921329 DOI: 10.1158/0008-5472.CAN-15-2162  1
2015 Wu L, Chen X, Zhao J, Martin B, Zepp JA, Ko JS, Gu C, Cai G, Ouyang W, Sen G, Stark GR, Su B, Vines CM, Tournier C, Hamilton TA, et al. A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis. The Journal of Experimental Medicine. PMID 26347473 DOI: 10.1084/jem.20150204  1
2015 Lu T, Stark GR. NF-κB: Regulation by Methylation. Cancer Research. PMID 26337909 DOI: 10.1158/0008-5472.CAN-15-1022  1
2015 Sung PS, Cheon H, Cho CH, Hong SH, Park DY, Seo HI, Park SH, Yoon SK, Stark GR, Shin EC. Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness. Proceedings of the National Academy of Sciences of the United States of America. PMID 26216956 DOI: 10.1073/pnas.1513341112  1
2015 De S, Zhou H, DeSantis D, Croniger CM, Li X, Stark GR. Erlotinib protects against LPS-induced Endotoxicity because TLR4 needs EGFR to signal. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195767 DOI: 10.1073/pnas.1511794112  1
2015 Dasgupta M, Dermawan JK, Willard B, Stark GR. STAT3-driven transcription depends upon the dimethylation of K49 by EZH2. Proceedings of the National Academy of Sciences of the United States of America. 112: 3985-90. PMID 25767098 DOI: 10.1073/pnas.1503152112  1
2015 Lu T, Stark GR. Using sequential immunoprecipitation and mass spectrometry to identify methylation of NF-κB. Methods in Molecular Biology (Clifton, N.J.). 1280: 383-93. PMID 25736762 DOI: 10.1007/978-1-4939-2422-6_23  1
2015 Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey-Bates EG, Edsbäcker E, Pellegrini P, Rassoolzadeh H, Brnjic S, Larsson R, Stark GR, Grandér D, Linder S, Tamm KP, et al. Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs. International Journal of Cancer. Journal International Du Cancer. 136: E51-61. PMID 25156627 DOI: 10.1002/ijc.29161  1
2014 Dasgupta M, Unal H, Willard B, Yang J, Karnik SS, Stark GR. Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3. The Journal of Biological Chemistry. 289: 30763-71. PMID 25217633 DOI: 10.1074/jbc.M114.603894  1
2014 De S, Dermawan JK, Stark GR. EGF receptor uses SOS1 to drive constitutive activation of NFκB in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 11721-6. PMID 25071181 DOI: 10.1073/pnas.1412390111  1
2014 Dermawan JK, Gurova K, Pink J, Dowlati A, De S, Narla G, Sharma N, Stark GR. Quinacrine overcomes resistance to erlotinib by inhibiting FACT, NF-κB, and cell-cycle progression in non-small cell lung cancer. Molecular Cancer Therapeutics. 13: 2203-14. PMID 25028470 DOI: 10.1158/1535-7163.MCT-14-0013  1
2014 Cheon H, Borden EC, Stark GR. Interferons and their stimulated genes in the tumor microenvironment. Seminars in Oncology. 41: 156-73. PMID 24787290 DOI: 10.1053/j.seminoncol.2014.02.002  1
2014 Wienerroither S, Shukla P, Farlik M, Majoros A, Stych B, Vogl C, Cheon HJ, Stark GR, Strobl B, Müller M, Decker T. Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex Cell Reports. DOI: 10.1016/j.celrep.2015.06.021  1
2013 Qiu J, Thapaliya S, Runkana A, Yang Y, Tsien C, Mohan ML, Narayanan A, Eghtesad B, Mozdziak PE, McDonald C, Stark GR, Welle S, Naga Prasad SV, Dasarathy S. Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB-mediated mechanism. Proceedings of the National Academy of Sciences of the United States of America. 110: 18162-7. PMID 24145431 DOI: 10.1073/pnas.1317049110  1
2013 Wang Y, van Boxel-Dezaire AH, Cheon H, Yang J, Stark GR. STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor. Proceedings of the National Academy of Sciences of the United States of America. 110: 16975-80. PMID 24082147 DOI: 10.1073/pnas.1315862110  1
2013 Cheon H, Holvey-Bates EG, Schoggins JW, Forster S, Hertzog P, Imanaka N, Rice CM, Jackson MW, Junk DJ, Stark GR. IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage. The Embo Journal. 32: 2751-63. PMID 24065129 DOI: 10.1038/emboj.2013.203  1
2013 Lu T, Yang M, Huang DB, Wei H, Ozer GH, Ghosh G, Stark GR. Role of lysine methylation of NF-κB in differential gene regulation. Proceedings of the National Academy of Sciences of the United States of America. 110: 13510-5. PMID 23904479 DOI: 10.1073/pnas.1311770110  1
2013 Wei H, Wang B, Miyagi M, She Y, Gopalan B, Huang DB, Ghosh G, Stark GR, Lu T. PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB. Proceedings of the National Academy of Sciences of the United States of America. 110: 13516-21. PMID 23904475 DOI: 10.1073/pnas.1311784110  1
2013 Zhang T, Park KA, Li Y, Byun HS, Jeon J, Lee Y, Hong JH, Kim JM, Huang SM, Choi SW, Kim SH, Sohn KC, Ro H, Lee JH, Lu T, ... Stark GR, et al. PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65. Nature Communications. 4: 2062. PMID 23797602 DOI: 10.1038/ncomms3062  1
2012 Cipriano R, Graham J, Miskimen KL, Bryson BL, Bruntz RC, Scott SA, Brown HA, Stark GR, Jackson MW. FAM83B mediates EGFR- and RAS-driven oncogenic transformation. The Journal of Clinical Investigation. 122: 3197-210. PMID 22886302 DOI: 10.1172/JCI60517  1
2012 Stark GR, Darnell JE. The JAK-STAT pathway at twenty. Immunity. 36: 503-14. PMID 22520844 DOI: 10.1016/j.immuni.2012.03.013  1
2012 Tan MH, De S, Bebek G, Orloff MS, Wesolowski R, Downs-Kelly E, Budd GT, Stark GR, Eng C. Specific kinesin expression profiles associated with taxane resistance in basal-like breast cancer. Breast Cancer Research and Treatment. 131: 849-58. PMID 21479552 DOI: 10.1007/s10549-011-1500-8  1
2011 Zula JA, Green HC, Ransohoff RM, Rudick RA, Stark GR, van Boxel-Dezaire AH. The role of cell type-specific responses in IFN-β therapy of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 108: 19689-94. PMID 22106296 DOI: 10.1073/pnas.1117347108  1
2011 Velazquez L, Fellous M, Stark GR, Pellegrini S. Pillars article: A protein tyrosine kinase in the interferon α/β signaling pathway. Cell. 1992. 70: 313-322. Journal of Immunology (Baltimore, Md. : 1950). 187: 5479-88. PMID 22102731  1
2011 Sears N, Sen GC, Stark GR, Chattopadhyay S. Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation. The Journal of Biological Chemistry. 286: 33037-44. PMID 21816816 DOI: 10.1074/jbc.M111.257022  1
2011 Guo C, Stark GR. FER tyrosine kinase (FER) overexpression mediates resistance to quinacrine through EGF-dependent activation of NF-kappaB. Proceedings of the National Academy of Sciences of the United States of America. 108: 7968-73. PMID 21518868 DOI: 10.1073/pnas.1105369108  1
2011 Guryanova OA, Wu Q, Cheng L, Lathia JD, Huang Z, Yang J, MacSwords J, Eyler CE, McLendon RE, Heddleston JM, Shou W, Hambardzumyan D, Lee J, Hjelmeland AB, Sloan AE, ... ... Stark GR, et al. Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell. 19: 498-511. PMID 21481791 DOI: 10.1016/j.ccr.2011.03.004  1
2011 Wan Y, Kim TW, Yu M, Zhou H, Yamashita M, Kang Z, Yin W, Wang JA, Thomas J, Sen GC, Stark GR, Li X. The dual functions of IL-1 receptor-associated kinase 2 in TLR9-mediated IFN and proinflammatory cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 186: 3006-14. PMID 21270393 DOI: 10.4049/jimmunol.1003217  1
2011 Cheon H, Yang J, Stark GR. The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 33-40. PMID 21166594 DOI: 10.1089/jir.2010.0100  1
2011 Stark GR, Wang Y, Lu T. Lysine methylation of promoter-bound transcription factors and relevance to cancer. Cell Research. 21: 375-80. PMID 21151202 DOI: 10.1038/cr.2010.174  1
2010 Yang J, Huang J, Dasgupta M, Sears N, Miyagi M, Wang B, Chance MR, Chen X, Du Y, Wang Y, An L, Wang Q, Lu T, Zhang X, Wang Z, ... Stark GR, et al. Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. Proceedings of the National Academy of Sciences of the United States of America. 107: 21499-504. PMID 21098664 DOI: 10.1073/pnas.1016147107  1
2010 van Boxel-Dezaire AH, Zula JA, Xu Y, Ransohoff RM, Jacobberger JW, Stark GR. Major differences in the responses of primary human leukocyte subsets to IFN-beta. Journal of Immunology (Baltimore, Md. : 1950). 185: 5888-99. PMID 20956346 DOI: 10.4049/jimmunol.0902314  1
2010 Wan Y, Yang M, Kolattukudy S, Stark GR, Lu T. Activation of cAMP-responsive-element-binding protein by PI3 kinase and p38 MAPK is essential for elevated expression of transforming growth factor β2 in cancer cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 30: 677-81. PMID 20629536 DOI: 10.1089/jir.2009.0117  1
2010 Lu T, Stark GR. Use of forward genetics to discover novel regulators of NF-kappaB. Cold Spring Harbor Perspectives in Biology. 2: a001966. PMID 20516132 DOI: 10.1101/cshperspect.a001966  1
2010 Lu T, Jackson MW, Wang B, Yang M, Chance MR, Miyagi M, Gudkov AV, Stark GR. Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65. Proceedings of the National Academy of Sciences of the United States of America. 107: 46-51. PMID 20080798 DOI: 10.1073/pnas.0912493107  1
2009 Shultz DB, Rani MR, Fuller JD, Ransohoff RM, Stark GR. Roles of IKK-beta, IRF1, and p65 in the activation of chemokine genes by interferon-gamma. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 29: 817-24. PMID 19929594 DOI: 10.1089/jir.2009.0034  1
2009 Lu T, Jackson MW, Singhi AD, Kandel ES, Yang M, Zhang Y, Gudkov AV, Stark GR. Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proceedings of the National Academy of Sciences of the United States of America. 106: 16339-44. PMID 19805303 DOI: 10.1073/pnas.0908560106  1
2009 De S, Cipriano R, Jackson MW, Stark GR. Overexpression of kinesins mediates docetaxel resistance in breast cancer cells. Cancer Research. 69: 8035-42. PMID 19789344 DOI: 10.1158/0008-5472.CAN-09-1224  1
2009 Cheon H, Stark GR. Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes. Proceedings of the National Academy of Sciences of the United States of America. 106: 9373-8. PMID 19478064 DOI: 10.1073/pnas.0903487106  1
2009 Wan Y, Xiao H, Affolter J, Kim TW, Bulek K, Chaudhuri S, Carlson D, Hamilton T, Mazumder B, Stark GR, Thomas J, Li X. Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control. The Journal of Biological Chemistry. 284: 10367-75. PMID 19224918 DOI: 10.1074/jbc.M807822200  1
2008 Dasgupta M, Agarwal MK, Varley P, Lu T, Stark GR, Kandel ES. Transposon-based mutagenesis identifies short RIP1 as an activator of NFkappaB. Cell Cycle (Georgetown, Tex.). 7: 2249-56. PMID 18635966  1
2008 Hastak K, Paul RK, Agarwal MK, Thakur VS, Amin AR, Agrawal S, Sramkoski RM, Jacobberger JW, Jackson MW, Stark GR, Agarwal ML. DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation. Proceedings of the National Academy of Sciences of the United States of America. 105: 6314-9. PMID 18434539 DOI: 10.1073/pnas.0802080105  1
2008 Yang J, Stark GR. Roles of unphosphorylated STATs in signaling. Cell Research. 18: 443-51. PMID 18364677 DOI: 10.1038/cr.2008.41  1
2007 Borden EC, Sen GC, Uze G, Silverman RH, Ransohoff RM, Foster GR, Stark GR. Interferons at age 50: past, current and future impact on biomedicine. Nature Reviews. Drug Discovery. 6: 975-90. PMID 18049472 DOI: 10.1038/nrd2422  1
2007 Shultz DB, Fuller JD, Yang Y, Sizemore N, Rani MR, Stark GR. Activation of a subset of genes by IFN-gamma requires IKKbeta but not interferon-dependent activation of NF-kappaB. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 27: 875-84. PMID 17970697 DOI: 10.1089/jir.2007.0031  1
2007 van Boxel-Dezaire AH, Stark GR. Cell type-specific signaling in response to interferon-gamma. Current Topics in Microbiology and Immunology. 316: 119-54. PMID 17969446 DOI: 10.1007/978-3-540-71329-6-7  1
2007 Kan CE, Patton JT, Stark GR, Jackson MW. p53-mediated growth suppression in response to Nutlin-3 in cyclin D1 transformed cells occurs independently of p21. Cancer Research. 67: 9862-8. PMID 17942917 DOI: 10.1158/0008-5472.CAN-07-0259  1
2007 Stark GR. How cells respond to interferons revisited: from early history to current complexity. Cytokine & Growth Factor Reviews. 18: 419-23. PMID 17683974 DOI: 10.1016/j.cytogfr.2007.06.013  1
2007 Agrawal S, Febbraio M, Podrez E, Cathcart MK, Stark GR, Chisolm GM. Signal transducer and activator of transcription 1 is required for optimal foam cell formation and atherosclerotic lesion development. Circulation. 115: 2939-47. PMID 17533179 DOI: 10.1161/CIRCULATIONAHA.107.696922  1
2007 Yang J, Liao X, Agarwal MK, Barnes L, Auron PE, Stark GR. Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB. Genes & Development. 21: 1396-408. PMID 17510282 DOI: 10.1101/gad.1553707  1
2007 Lu T, Tian L, Han Y, Vogelbaum M, Stark GR. Dose-dependent cross-talk between the transforming growth factor-beta and interleukin-1 signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 104: 4365-70. PMID 17360530 DOI: 10.1073/pnas.0700118104  1
2006 Agarwal MK, Hastak K, Jackson MW, Breit SN, Stark GR, Agarwal ML. Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors. Proceedings of the National Academy of Sciences of the United States of America. 103: 16278-83. PMID 17050687 DOI: 10.1073/pnas.0607210103  1
2006 van Boxel-Dezaire AH, Rani MR, Stark GR. Complex modulation of cell type-specific signaling in response to type I interferons. Immunity. 25: 361-72. PMID 16979568 DOI: 10.1016/j.immuni.2006.08.014  1
2006 Stark GR, Taylor WR. Control of the G2/M transition. Molecular Biotechnology. 32: 227-48. PMID 16632889 DOI: 10.1385/MB:32:3:227  1
2006 Jackson MW, Patt LE, LaRusch GA, Donner DB, Stark GR, Mayo LD. Hdm2 nuclear export, regulated by insulin-like growth factor-I/MAPK/p90Rsk signaling, mediates the transformation of human cells. The Journal of Biological Chemistry. 281: 16814-20. PMID 16621805 DOI: 10.1074/jbc.M511617200  1
2006 Patton JT, Mayo LD, Singhi AD, Gudkov AV, Stark GR, Jackson MW. Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3. Cancer Research. 66: 3169-76. PMID 16540668 DOI: 10.1158/0008-5472.CAN-05-3832  1
2005 Gurova KV, Hill JE, Guo C, Prokvolit A, Burdelya LG, Samoylova E, Khodyakova AV, Ganapathi R, Ganapathi M, Tararova ND, Bosykh D, Lvovskiy D, Webb TR, Stark GR, Gudkov AV. Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors. Proceedings of the National Academy of Sciences of the United States of America. 102: 17448-53. PMID 16287968 DOI: 10.1073/pnas.0508888102  1
2005 Marques JT, Rebouillat D, Ramana CV, Murakami J, Hill JE, Gudkov A, Silverman RH, Stark GR, Williams BR. Down-regulation of p53 by double-stranded RNA modulates the antiviral response. Journal of Virology. 79: 11105-14. PMID 16103161 DOI: 10.1128/JVI.79.17.11105-11114.2005  1
2005 Kandel ES, Lu T, Wan Y, Agarwal MK, Jackson MW, Stark GR. Mutagenesis by reversible promoter insertion to study the activation of NF-kappaB. Proceedings of the National Academy of Sciences of the United States of America. 102: 6425-30. PMID 15851657 DOI: 10.1073/pnas.0502463102  1
2005 Jackson MW, Agarwal MK, Yang J, Bruss P, Uchiumi T, Agarwal ML, Stark GR, Taylor WR. p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2. Journal of Cell Science. 118: 1821-32. PMID 15827088 DOI: 10.1242/jcs.02307  1
2005 Yang J, Chatterjee-Kishore M, Staugaitis SM, Nguyen H, Schlessinger K, Levy DE, Stark GR. Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation. Cancer Research. 65: 939-47. PMID 15705894  1
2005 Stark GR. My life in science, not the restaurant business. The Journal of Biological Chemistry. 280: 9753-60. PMID 15632125 DOI: 10.1074/jbc.X400011200  1
2005 Qing Y, Costa-Pereira AP, Watling D, Stark GR. Role of tyrosine 441 of interferon-gamma receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation. The Journal of Biological Chemistry. 280: 1849-53. PMID 15522878 DOI: 10.1074/jbc.M409863200  1
2004 Lu T, Stark GR. Cytokine overexpression and constitutive NFkappaB in cancer. Cell Cycle (Georgetown, Tex.). 3: 1114-7. PMID 15492502  1
2004 Qing Y, Stark GR. Alternative activation of STAT1 and STAT3 in response to interferon-gamma. The Journal of Biological Chemistry. 279: 41679-85. PMID 15284232 DOI: 10.1074/jbc.M406413200  1
2004 Stark GR, Taylor WR. Analyzing the G2/M checkpoint. Methods in Molecular Biology (Clifton, N.J.). 280: 51-82. PMID 15187249 DOI: 10.1385/1-59259-788-2:051  1
2004 Sizemore N, Agarwal A, Das K, Lerner N, Sulak M, Rani S, Ransohoff R, Shultz D, Stark GR. Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes. Proceedings of the National Academy of Sciences of the United States of America. 101: 7994-8. PMID 15148408 DOI: 10.1073/pnas.0401593101  1
2004 Lu T, Burdelya LG, Swiatkowski SM, Boiko AD, Howe PH, Stark GR, Gudkov AV. Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 7112-7. PMID 15118089 DOI: 10.1073/pnas.0402048101  1
2004 Jackson MW, Agarwal MK, Agarwal ML, Agarwal A, Stanhope-Baker P, Williams BR, Stark GR. Limited role of N-terminal phosphoserine residues in the activation of transcription by p53. Oncogene. 23: 4477-87. PMID 15064747 DOI: 10.1038/sj.onc.1207575  1
2004 Jin G, Klika A, Callahan M, Faga B, Danzig J, Jiang Z, Li X, Stark GR, Harrington J, Sherf B. Identification of a human NF-kappaB-activating protein, TAB3. Proceedings of the National Academy of Sciences of the United States of America. 101: 2028-33. PMID 14766965 DOI: 10.1073/pnas.0307314101  1
2004 Sathe SS, Sizemore N, Li X, Vithalani K, Commane M, Swiatkowski SM, Stark GR. Mutant human cells with constitutive activation of NF-kappaB. Proceedings of the National Academy of Sciences of the United States of America. 101: 192-7. PMID 14691254 DOI: 10.1073/pnas.0306812101  1
2004 Lu T, Sathe SS, Swiatkowski SM, Hampole CV, Stark GR. Secretion of cytokines and growth factors as a general cause of constitutive NFkappaB activation in cancer. Oncogene. 23: 2138-45. PMID 14676835 DOI: 10.1038/sj.onc.1207332  1
2003 Wald D, Qin J, Zhao Z, Qian Y, Naramura M, Tian L, Towne J, Sims JE, Stark GR, Li X. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nature Immunology. 4: 920-7. PMID 12925853 DOI: 10.1038/ni968  1
2003 Clifford B, Beljin M, Stark GR, Taylor WR. G2 arrest in response to topoisomerase II inhibitors: the role of p53. Cancer Research. 63: 4074-81. PMID 12874009  1
2003 Zhang J, Yang J, Roy SK, Tininini S, Hu J, Bromberg JF, Poli V, Stark GR, Kalvakolanu DV. The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3. Proceedings of the National Academy of Sciences of the United States of America. 100: 9342-7. PMID 12867595 DOI: 10.1073/pnas.1633516100  1
2003 Nguyen H, Chatterjee-Kishore M, Jiang Z, Qing Y, Ramana CV, Bayes J, Commane M, Li X, Stark GR. IRAK-dependent phosphorylation of Stat1 on serine 727 in response to interleukin-1 and effects on gene expression. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 23: 183-92. PMID 12856330 DOI: 10.1089/107999003765027384  1
2002 Rani MR, Hibbert L, Sizemore N, Stark GR, Ransohoff RM. Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene. The Journal of Biological Chemistry. 277: 38456-61. PMID 12169689 DOI: 10.1074/jbc.M203204200  1
2002 Chawla-Sarkar M, Leaman DW, Jacobs BS, Tuthill RJ, Chatterjee-Kishore M, Stark GR, Borden EC. Resistance to interferons in melanoma cells does not correlate with the expression or activation of signal transducer and activator of transcription 1 (Stat1). Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 22: 603-13. PMID 12060499 DOI: 10.1089/10799900252982089  1
2002 Peters KL, Smith HL, Stark GR, Sen GC. IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA. Proceedings of the National Academy of Sciences of the United States of America. 99: 6322-7. PMID 11972054 DOI: 10.1073/pnas.092133199  1
2002 Li X, Stark GR. NFkappaB-dependent signaling pathways. Experimental Hematology. 30: 285-96. PMID 11937262 DOI: 10.1016/S0301-472X(02)00777-4  1
2002 Ramana CV, Gil MP, Schreiber RD, Stark GR. Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling. Trends in Immunology. 23: 96-101. PMID 11929133 DOI: 10.1016/S1471-4906(01)02118-4  1
2002 Wong LH, Sim H, Chatterjee-Kishore M, Hatzinisiriou I, Devenish RJ, Stark G, Ralph SJ. Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1 Journal of Biological Chemistry. 277: 19408-19417. PMID 11909852 DOI: 10.1074/jbc.M111302200  1
2002 Agrawal S, Agarwal ML, Chatterjee-Kishore M, Stark GR, Chisolm GM. Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis. Molecular and Cellular Biology. 22: 1981-92. PMID 11884587 DOI: 10.1128/MCB.22.7.1981-1992.2002  1
2002 Sizemore N, Lerner N, Dombrowski N, Sakurai H, Stark GR. Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B. The Journal of Biological Chemistry. 277: 3863-9. PMID 11733537 DOI: 10.1074/jbc.M110572200  1
2002 Bean LJ, Stark GR. Regulation of the accumulation and function of p53 by phosphorylation of two residues within the domain that binds to Mdm2. The Journal of Biological Chemistry. 277: 1864-71. PMID 11707453 DOI: 10.1074/jbc.M108881200  1
2002 Wagner TC, Velichko S, Vogel D, Rani MR, Leung S, Ransohoff RM, Stark GR, Perez HD, Croze E. Interferon signaling is dependent on specific tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cells. The Journal of Biological Chemistry. 277: 1493-9. PMID 11682488 DOI: 10.1074/jbc.M108928200  1
2001 Wald D, Commane M, Stark GR, Li X. IRAK and TAK1 are required for IL-18-mediated signaling. European Journal of Immunology. 31: 3747-54. PMID 11745395 DOI: 10.1002/1521-4141(200112)31:12<3747::AID-IMMU3747>3.0.CO;2-E  1
2001 Rani MR, Asthagiri AR, Singh A, Sizemore N, Sathe SS, Li X, DiDonato JD, Stark GR, Ransohoff RM. A role for NF-kappa B in the induction of beta-R1 by interferon-beta. The Journal of Biological Chemistry. 276: 44365-8. PMID 11591697 DOI: 10.1074/jbc.C100417200  1
2001 Girardin SE, Tournebize R, Mavris M, Page AL, Li X, Stark GR, Bertin J, DiStefano PS, Yaniv M, Sansonetti PJ, Philpott DJ. CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. Embo Reports. 2: 736-42. PMID 11463746 DOI: 10.1093/embo-reports/kve155  1
2001 Nguyen H, Ramana CV, Bayes J, Stark GR. Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression. The Journal of Biological Chemistry. 276: 33361-8. PMID 11438544 DOI: 10.1074/jbc.M105070200  1
2001 Chernov MV, Bean LJ, Lerner N, Stark GR. Regulation of ubiquitination and degradation of p53 in unstressed cells through C-terminal phosphorylation. The Journal of Biological Chemistry. 276: 31819-24. PMID 11431470 DOI: 10.1074/jbc.M103170200  1
2001 Agarwal ML, Ramana CV, Hamilton M, Taylor WR, DePrimo SE, Bean LJ, Agarwal A, Agarwal MK, Wolfman A, Stark GR. Regulation of p53 expression by the RAS-MAP kinase pathway. Oncogene. 20: 2527-36. PMID 11420662 DOI: 10.1038/sj.onc.1204353  1
2001 Gil MP, Bohn E, O'Guin AK, Ramana CV, Levine B, Stark GR, Virgin HW, Schreiber RD. Biologic consequences of Stat1-independent IFN signaling. Proceedings of the National Academy of Sciences of the United States of America. 98: 6680-5. PMID 11390995 DOI: 10.1073/pnas.111163898  1
2001 Ramana CV, Gil MP, Han Y, Ransohoff RM, Schreiber RD, Stark GR. Stat1-independent regulation of gene expression in response to IFN-gamma. Proceedings of the National Academy of Sciences of the United States of America. 98: 6674-9. PMID 11390994 DOI: 10.1073/pnas.111164198  1
2001 Bean LJ, Stark GR. Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV. Oncogene. 20: 1076-84. PMID 11314044 DOI: 10.1038/sj.onc.1204204  1
2001 Taylor WR, Stark GR. Regulation of the G2/M transition by p53. Oncogene. 20: 1803-15. PMID 11313928 DOI: 10.1038/sj.onc.1204252  1
2001 Li X, Commane M, Jiang Z, Stark GR. IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK). Proceedings of the National Academy of Sciences of the United States of America. 98: 4461-5. PMID 11287640 DOI: 10.1073/pnas.071054198  1
2001 Takaesu G, Ninomiya-Tsuji J, Kishida S, Li X, Stark GR, Matsumoto K. Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Molecular and Cellular Biology. 21: 2475-84. PMID 11259596 DOI: 10.1128/MCB.21.7.2475-2484.2001  1
2001 Taylor WR, Schonthal AH, Galante J, Stark GR. p130/E2F4 binds to and represses the cdc2 promoter in response to p53. The Journal of Biological Chemistry. 276: 1998-2006. PMID 11032828 DOI: 10.1074/jbc.M005101200  1
2000 Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR. Act1, an NF-kappa B-activating protein. Proceedings of the National Academy of Sciences of the United States of America. 97: 10489-93. PMID 10962024 DOI: 10.1073/pnas.160265197  1
2000 Chatterjee-Kishore M, Wright KL, Ting JP, Stark GR. How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene. The Embo Journal. 19: 4111-22. PMID 10921891 DOI: 10.1093/emboj/19.15.4111  1
2000 Farrar JD, Smith JD, Murphy TL, Leung S, Stark GR, Murphy KM. Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2. Nature Immunology. 1: 65-9. PMID 10881177 DOI: 10.1038/76932  1
2000 Mohan RR, Mohan RR, Kim WJ, Stark GR, Wilson SE. Defective keratocyte apoptosis in response to epithelial injury in stat 1 null mice. Experimental Eye Research. 70: 485-91. PMID 10865997 DOI: 10.1006/exer.1999.0807  1
2000 Ramana CV, Chatterjee-Kishore M, Nguyen H, Stark GR. Complex roles of Stat1 in regulating gene expression. Oncogene. 19: 2619-27. PMID 10851061 DOI: 10.1038/sj.onc.1203525  1
2000 Chatterjee-Kishore M, van Den Akker F, Stark GR. Adenovirus E1A down-regulates LMP2 transcription by interfering with the binding of stat1 to IRF1. The Journal of Biological Chemistry. 275: 20406-11. PMID 10764778 DOI: 10.1074/jbc.M001861200  1
2000 Albrecht EB, Hunyady AB, Stark GR, Patterson TE. Mechanisms of sod2 gene amplification in Schizosaccharomyces pombe. Molecular Biology of the Cell. 11: 873-86. PMID 10712506  1
2000 Chatterjee-Kishore M, van den Akker F, Stark GR. Association of STATs with relatives and friends. Trends in Cell Biology. 10: 106-11. PMID 10675904 DOI: 10.1016/S0962-8924(99)01709-2  1
2000 Ramana CV, Grammatikakis N, Chernov M, Nguyen H, Goh KC, Williams BRG, Stark GR. Regulation of c-myc expression by IFN-γ through Stat1-dependent and -independent pathways Embo Journal. 19: 263-272. PMID 10637230  1
1999 Taylor WR, DePrimo SE, Agarwal A, Agarwal ML, Schönthal AH, Katula KS, Stark GR. Mechanisms of G2 arrest in response to overexpression of p53 Molecular Biology of the Cell. 10: 3607-3622. PMID 10564259  1
1999 Stark GR, Gudkov AV. Forward genetics in mammalian cells: Functional approaches to gene discovery Human Molecular Genetics. 8: 1925-1938. PMID 10469846 DOI: 10.1093/hmg/8.10.1925  1
1999 Patterson TE, Albrecht EB, Nurse P, Sazer S, Stark GR. Effects of genome position and the DNA damage checkpoint on the structure and frequency of sod2 gene amplification in fission yeast. Molecular Biology of the Cell. 10: 2199-208. PMID 10397759  1
1999 Wesche H, Gao X, Li X, Kirschning CJ, Stark GR, Cao Z. IRAK-M is a novel member of the pelle/interleukin-1 receptor-associated kinase (IRAK) family Journal of Biological Chemistry. 274: 19403-19410. PMID 10383454 DOI: 10.1074/jbc.274.27.19403  1
1999 Sizemore N, Leung S, Stark GR. Activation of phosphatidylinositol 3-kinase in response to interleukin- 1 leads to phosphorylation and activation of the NF-κB p65/RelA subunit Molecular and Cellular Biology. 19: 4798-4805. PMID 10373529  1
1999 Li X, Commane M, Burns C, Vithalani K, Cao Z, Stark GR. Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase Molecular and Cellular Biology. 19: 4643-4652. PMID 10373513  1
1999 Taylor WR, Agarwal ML, Agarwal A, Stacey DW, Stark GR. p53 inhibits entry into mitosis when DNA synthesis is blocked Oncogene. 18: 283-295. PMID 9927185 DOI: 10.1038/sj.onc.1202516  1
1998 Li X, Leung S, Burns C, Stark GR. Cooperative binding of stat1-2 heterodimers and ISGF3 to tandem DNA elements Biochimie. 80: 703-710. PMID 9865492 DOI: 10.1016/S0300-9084(99)80023-6  1
1998 Agarwal ML, Agarwal A, Taylor WR, Chernova O, Sharma Y, Stark GR. A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides Proceedings of the National Academy of Sciences of the United States of America. 95: 14775-14780. PMID 9843965 DOI: 10.1073/pnas.95.25.14775  1
1998 Lackmann M, Harpur AG, Oates AC, Mann RJ, Gabriel A, Meutermans W, Alewood PF, Kerr IM, Stark GR, Wilks AF. Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: prevalence of latent STAT1 in high-molecular weight complexes. Growth Factors (Chur, Switzerland). 16: 39-51. PMID 9777369  1
1998 Leaman DW, Salvekar A, Patel R, Sen GC, Stark GR. A mutant cell line defective in response to double-stranded RNA and in regulating basal expression of interferon-stimulated genes Proceedings of the National Academy of Sciences of the United States of America. 95: 9442-9447. PMID 9689099 DOI: 10.1073/pnas.95.16.9442  1
1998 Yamauchi T, Yasushi K, Ueki K, Tsuji Y, Stark GR, Kerr IM, Tsushima T, Akanuma Y, Komuro I, Tobe K, Yazaki Y, Kadowaki T. Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase Journal of Biological Chemistry. 273: 15719-15726. PMID 9624169 DOI: 10.1074/jbc.273.25.15719  1
1998 Wright KL, Chin KC, Linhoff M, Skinner C, Brown JA, Boss JM, Stark GR, Ting JP. CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 6267-72. PMID 9600954 DOI: 10.1073/pnas.95.11.6267  1
1998 Chernov MV, Ramana CV, Adler VV, Stark GR. Stabilization and activation of p53 are regulated independently by different phosphorylation events Proceedings of the National Academy of Sciences of the United States of America. 95: 2284-2289. PMID 9482877 DOI: 10.1073/pnas.95.5.2284  1
1998 Chernova OB, Chernov MV, Ishizaka Y, Agarwal ML, Stark GR. MYC abrogates p53-mediated cell cycle arrest in N-(phosphonacetyl)-L- aspartate-treated cells, permitting CAD gene amplification Molecular and Cellular Biology. 18: 536-545. PMID 9418900  1
1998 Agarwal ML, Taylor WR, Chernov MV, Chernova OB, Stark GR. The p53 network Journal of Biological Chemistry. 273: 1-4. PMID 9417035 DOI: 10.1074/jbc.273.1.1  1
1997 Stark GR. Genetic analysis of interferon and other mammalian signaling pathways Harvey Lectures. 93: 1-16. PMID 10941415  1
1997 Kumar A, Commane M, Flickinger TW, Horvath CM, Stark GR. Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases Science. 278: 1630-1632. PMID 9374464 DOI: 10.1126/science.278.5343.1630  1
1997 Agarwal ML, Agarwal A, Taylor WR, Wang ZQ, Wagner EF, Stark GR. Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase Oncogene. 15: 1035-1041. PMID 9285557  1
1997 Haque SJ, Wu Q, Kammer W, Friedrich K, Smith JM, Kerr IM, Stark GR, Williams BRG. Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1 Proceedings of the National Academy of Sciences of the United States of America. 94: 8563-8568. PMID 9238016 DOI: 10.1073/pnas.94.16.8563  1
1997 Shimoda K, Feng J, Murakami H, Nagata S, Watling D, Rogers NC, Stark GR, Kerr IM, Ihle JN. Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor. Blood. 90: 597-604. PMID 9226159  1
1997 Han Y, Watling D, Rogers NC, Stark GR. JAK2 and STAT5, but not JAK1 and STAT1, are required for prolactin- induced β-lactoglobulin transcription Molecular Endocrinology. 11: 1180-1188. PMID 9212064 DOI: 10.1210/me.11.8.1180  1
1997 Chernov MV, Stark GR. The p53 activation and apoptosis induced by DNA damage are reversibly inhibited by salicylate Oncogene. 14: 2503-2510. PMID 9191050 DOI: 10.1038/sj.onc.1201104  1
1997 Komarova EA, Chernov MV, Franks R, Wang K, Armin G, Zelnick CR, Chin DM, Bacus SS, Stark GR, Gudkov AV. Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo Embo Journal. 16: 1391-1400. PMID 9135154 DOI: 10.1093/emboj/16.6.1391  1
1997 Li X, Leung S, Kerr IM, Stark GR. Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling Molecular and Cellular Biology. 17: 2048-2056. PMID 9121453  1
1997 Smith KA, Chernova OB, Groves RP, Stark MB, Martínez JL, Davidson JN, Trent JM, Patterson TE, Agarwal A, Duncan P, Agarwal ML, Stark GR. Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged. Proceedings of the National Academy of Sciences of the United States of America. 94: 1816-21. PMID 9050862 DOI: 10.1073/pnas.94.5.1816  1
1997 Kohlhuber F, Rogers NC, Watling D, Feng J, Guschin D, Briscoe J, Witthuhn BA, Kotenko SV, Pestka S, Stark GR, Ihle JN, Kerr IM. A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses. Molecular and Cellular Biology. 17: 695-706. PMID 9001223  1
1996 Leaman DW, Leung S, Li X, Stark GR. Regulation of STAT-dependent pathways by growth factors and cytokines Faseb Journal. 10: 1578-1588. PMID 9002549  1
1996 Foster GR, Rodrigues O, Ghouze F, Schulte-Frohlinde E, Testa D, Liao MJ, Stark GR, Leadbeater L, Thomas HC. Different relative activities of human cell-derived interferon-α subtypes: IFN-α8 has very high antiviral potency Journal of Interferon and Cytokine Research. 16: 1027-1033. PMID 8974005  1
1996 Horvath CM, Stark GR, Kerr IM, Darnell JE. Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex. Molecular and Cellular Biology. 16: 6957-64. PMID 8943351  1
1996 Poupon MF, Smith KA, Chernova OB, Gilbert C, Stark GR. Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles Molecular Biology of the Cell. 7: 345-354. PMID 8868464  1
1996 Ossovskaya VS, Mazo IA, Chernov MV, Chernova OB, Strezoska Z, Kondratov R, Stark GR, Chumakov PM, Gudkov AV. Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains Proceedings of the National Academy of Sciences of the United States of America. 93: 10309-10314. PMID 8816796 DOI: 10.1073/pnas.93.19.10309  1
1996 Sandhya Rani MR, Foster GR, Leung S, Leaman D, Stark GR, Ransohoff RM. Characterization of β-R1, a gene that is selectively induced by interferon β (IFN-β) compared with IFN-α Journal of Biological Chemistry. 271: 22878-22884. PMID 8798467 DOI: 10.1074/jbc.271.37.22878  1
1996 Leung S, Li X, Stark GR. STATs find that hanging together can be stimulating Science. 273: 750-751. PMID 8701326  1
1996 Briscoe J, Rogers NC, Witthuhn BA, Watling D, Harpur AG, Wilks AF, Stark GR, Ihle JN, Kerr IM. Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state. The Embo Journal. 15: 799-809. PMID 8631301  1
1996 Han Y, Leaman DW, Watling D, Rogers NC, Groner B, Kerr IM, Wood WI, Stark GR. Participation of JAK and STAT proteins in growth hormone-induced signaling Journal of Biological Chemistry. 271: 5947-5952. PMID 8621469 DOI: 10.1074/jbc.271.10.5947  1
1996 Li X, Leung S, Qureshi S, Darnell JE, Stark GR. Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha. The Journal of Biological Chemistry. 271: 5790-4. PMID 8621447 DOI: 10.1074/jbc.271.10.5790  1
1996 Leaman DW, Pisharody S, Flickinger TW, Commane MA, Schlessinger J, Kerr IM, Levy DE, Stark GR. Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor. Molecular and Cellular Biology. 16: 369-75. PMID 8524316  1
1996 Qureshi SA, Leung S, Kerr IM, Stark GR, Darnell JE. Function of Stat2 protein in transcriptional activation by alpha interferon. Molecular and Cellular Biology. 16: 288-93. PMID 8524306  1
1995 Chernova OB, Chernov MV, Agarwal ML, Taylor WR, Stark GR. The role of p53 in regulating genomic stability when DNA and RNA synthesis are inhibited Trends in Biochemical Sciences. 20: 431-434. PMID 8533158 DOI: 10.1016/S0968-0004(00)89094-5  1
1995 Heim MH, Kerr IM, Stark GR, Darnell JE. Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway. Science (New York, N.Y.). 267: 1347-9. PMID 7871432  1
1995 Smith KA, Agarwal ML, Chernov MV, Chernova OB, Deguchi Y, Ishizaka Y, Patterson TE, Poupon MF, Stark GR. Regulation and mechanisms of gene amplification Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 347: 49-56. PMID 7746853  1
1995 Ishizaka Y, Chernov MV, Burns CM, Stark GR. p53-dependent growth arrest of REF52 cells containing newly amplified DNA Proceedings of the National Academy of Sciences of the United States of America. 92: 3224-3228. PMID 7724543  1
1995 Agarwal ML, Agarwal A, Taylor WR, Stark GR. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 92: 8493-8497. PMID 7667317  1
1995 Bandyopadhyay SK, Leonard GT, Bandyopadhyay T, Stark GR, Sen GC. Transcriptional induction by double-stranded RNA is mediated by interferon-stimulated response elements without activation of interferon-stimulated gene factor 3. The Journal of Biological Chemistry. 270: 19624-9. PMID 7642650  1
1995 Lu HT, Riley JL, Babcock GT, Huston M, Stark GR, Boss JM, Ransohoff RM. Interferon (IFN) beta acts downstream of IFN-gamma-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-gamma. The Journal of Experimental Medicine. 182: 1517-25. PMID 7595221  1
1995 Lutfalla G, Holland SJ, Cinato E, Monneron D, Reboul J, Rogers NC, Smith JM, Stark GR, Gardiner K, Mogensen KE, Kerr IM, Uze G. Mutant U5A cells are complemented by an interferon-αβ receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster Embo Journal. 14: 5100-5108. PMID 7588638  1
1995 Bluyssen HAR, Muzaffar R, Vlieststra RJ, Van Der Made ACJ, Leung S, Stark GR, Kerr IM, Trapman J, Levy DE. Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses Proceedings of the National Academy of Sciences of the United States of America. 92: 5645-5649. PMID 7539922  1
1995 Guschin D, Rogers N, Briscoe J, Witthuhn B, Watling D, Horn F, Pellegrini S, Yasukawa K, Heinrich P, Stark GR. A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6. The Embo Journal. 14: 1421-9. PMID 7537214  1
1995 Leung S, Qureshi SA, Kerr IM, Darnell JE, Stark GR. Role of STAT2 in the alpha interferon signaling pathway. Molecular and Cellular Biology. 15: 1312-7. PMID 7532278  1
1995 Patterson TE, Stark GR, Sazer S. A strategy for quickly identifying all unique two-hybrid or library plasmids within a pool of yeast transformants. Nucleic Acids Research. 23: 4222-3. PMID 7479088 DOI: 10.1093/nar/23.20.4222  1
1994 Darnell JE, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science (New York, N.Y.). 264: 1415-21. PMID 8197455  1
1994 Improta T, Schindler C, Horvath CM, Kerr IM, Stark GR, Darnell JE. Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 4776-80. PMID 8197134 DOI: 10.1073/pnas.91.11.4776  1
1994 McKendry R, Pellegrini S, Kerr IM, Stark GR. Constitutive production of alpha and beta interferons in mutant human cell lines Journal of Virology. 68: 4057-4062. PMID 8189543  1
1994 Chin KC, Mao C, Skinner C, Riley JL, Wright KL, Moreno CS, Stark GR, Boss JM, Ting JP. Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction. Immunity. 1: 687-97. PMID 7600294 DOI: 10.1016/1074-7613(94)90039-6  1
1993 Mao C, Davies D, Kerr IM, Stark GR. Mutant human cells defective in induction of major histocompatibility complex class II genes by interferon γ Proceedings of the National Academy of Sciences of the United States of America. 90: 2880-2884. PMID 8464903  1
1993 Stark GR. Regulation and mechanisms of mammalian gene amplification Advances in Cancer Research. 61: 87-113. PMID 8346721  1
1993 Müller M, Briscoe J, Laxton C, Guschin D, Ziemiecki A, Silvennoinen O, Harpur AG, Barbieri G, Witthuhn BA, Schindler C. The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction. Nature. 366: 129-35. PMID 8232552 DOI: 10.1038/366129a0  1
1993 Watling D, Guschin D, Müller M, Silvennoinen O, Witthuhn BA, Quelle FW, Rogers NC, Schindler C, Stark GR, Ihle JN, Kerr IM. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-γ signal transduction pathway Nature. 366: 166-170. PMID 7901766  1
1993 Müller M, Laxton C, Briscoe J, Schindler C, Improta T, Darnell JE, Stark GR, Kerr IM. Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways. The Embo Journal. 12: 4221-8. PMID 7693454  1
1993 Shuai K, Stark GR, Kerr IM, Darnell JE. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science (New York, N.Y.). 261: 1744-6. PMID 7690989  1
1993 Parrington J, Rogers NC, Gewert DR, Pine R, Veals SA, Levy DE, Stark GR, Kerr IM. The interferon-stimulable response elements of two human genes detect overlapping sets of transcription factors European Journal of Biochemistry. 214: 617-626. PMID 7686487  1
1993 Foster GR, Goldin RD, Hay A, McGarvey MJ, Stark GR, Thomas HC. Expression of the terminal protein of hepatitis B virus is associated with failure to respond to interferon therapy Hepatology. 17: 757-762. PMID 7684016  1
1992 Velazquez L, Fellous M, Stark GR, Pellegrini S. A protein tyrosine kinase in the interferon alpha/beta signaling pathway. Cell. 70: 313-22. PMID 1386289 DOI: 10.1016/0092-8674(92)90105-L  1
1992 Kerr IM, Stark GR. The antiviral effects of the interferons and their inhibition Journal of Interferon Research. 12: 237-240. PMID 1385551  1
1992 Stark GR, Kerr IM. Interferon-dependent signaling pathways: DNA elements, transcription factors, mutations, and effects of viral proteins Journal of Interferon Research. 12: 147-151. PMID 1379292  1
1992 Smith KA, Stark MB, Gorman PA, Stark GR. Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells Proceedings of the National Academy of Sciences of the United States of America. 89: 5427-5431. PMID 1351682  1
1992 Perry ME, Commane M, Stark GR. Simian virus 40 large tumor antigen alone or two cooperating oncogenes convert REF52 cells to a state permissive for gene amplification Proceedings of the National Academy of Sciences of the United States of America. 89: 8112-8116. PMID 1325647  1
1992 Perry ME, Rolfe M, McIntyre P, Commane M, Stark GR. Induction of gene amplification by 5-aza-2′-deoxycytidine Mutation Research - Reviews in Mutation Research. 276: 189-197. DOI: 10.1016/0165-1110(92)90008-W  1
1991 John J, Mckendry R, Pellegrini S, Flavell D, Kerr IM, Stark GR. Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons Molecular and Cellular Biology. 11: 4189-4195. PMID 1906577  1
1991 Lewin AR, Reid LE, McMahon M, Stark GR, Kerr IM. Molecular analysis of a human interferon-inducible gene family European Journal of Biochemistry. 199: 417-423. PMID 1906403  1
1991 Ackrill AM, Reid LE, Gilbert CS, Gewert DR, Porter ACG, Lewin AR, Stark GR, Kerr IM. Differential response of the human 6-16 and 9-27 genes to α and γ interferons Nucleic Acids Research. 19: 591-598. PMID 1901407  1
1991 Mckendry R, John J, Flavell D, Müller M, Kerr IM, Stark GR. High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both α and γ interferons Proceedings of the National Academy of Sciences of the United States of America. 88: 11455-11459. PMID 1837150  1
1991 Ackrill AM, Foster GR, Laxton CD, Flavell DM, Stark GR, Kerr IM. Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene Nucleic Acids Research. 19: 4387-4393. PMID 1832217  1
1991 Kerr IM, Stark GR. The control of interferon-inducible gene expression Febs Letters. 285: 194-198. PMID 1713174 DOI: 10.1016/0014-5793(91)80802-A  1
1991 Foster GR, Ackrill AM, Goldin RD, Kerr IM, Thomas HC, Stark GR. Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons α and γ and double-stranded RNA Proceedings of the National Academy of Sciences of the United States of America. 88: 2888-2892. PMID 1707174  1
1991 Foster GR, Ackrill AM, Golden RD, Goodbourn SE, Kerr IM, Thomas HC, Stark GR. Inhibitory effects of the hepatitis B virus on the cellular response to interferon International Journal of Experimental Pathology. 72: A14-A15.  1
1990 Wright JA, Smith HS, Watt FM, Hancock MC, Hudson DL, Stark GR. DNA amplification is rare in normal human cells Proceedings of the National Academy of Sciences of the United States of America. 87: 1791-1795. PMID 2308938  1
1990 McMillan TJ, Kalebic T, Stark GR, Hart IR. High frequency of double drug resistance in the B16 melanoma cell line European Journal of Cancer and Clinical Oncology. 26: 565-567. PMID 2144741 DOI: 10.1016/0277-5379(90)90077-7  1
1990 Imam AMA, Ackrill AM, Dale TC, Kerr IM, Stark GR. Transcription factors induced by interferons α and γ Nucleic Acids Research. 18: 6573-6580. PMID 2123539 DOI: 10.1093/nar/18.22.6573  1
1990 Smith KA, Gorman PA, Stark MB, Groves RP, Stark GR. Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells Cell. 63: 1219-1227. PMID 1979757 DOI: 10.1016/0092-8674(90)90417-D  1
1989 Stark GR, Debatisse M, Giulotto E, Wahl GM. Recent progress in understanding mechanisms of mammalian DNA amplification Cell. 57: 901-908. PMID 2661014 DOI: 10.1016/0092-8674(89)90328-0  1
1989 Saito I, Groves R, Giulotto E, Rolfe M, Stark GR. Evolution and stability of chromosomal DNA coamplified with the CAD gene Molecular and Cellular Biology. 9: 2445-2552. PMID 2569669  1
1989 Smith KA, Lewin AR, Stark GR. A method for mapping exons using mixed cDNA probes Methods in Molecular and Cellular Biology. 1: 133-141.  1
1984 Wells JA, Swyryd EA, Stark GR. An improved method for purifying 2',5'-oligoadenylate synthetases. The Journal of Biological Chemistry. 259: 1363-70. PMID 6693390  1
1982 Wahl GM, Vitto L, Padgett RA, Stark GR. Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization. Molecular and Cellular Biology. 2: 308-19. PMID 6180304  1
1982 Padgett RA, Wahl GM, Stark GR. Properties of dispersed, highly repeated DNA within and near the hamster CAD gene. Molecular and Cellular Biology. 2: 302-7. PMID 6180303  1
1982 Padgett RA, Wahl GM, Stark GR. Structure of the gene for CAD, the multifunctional protein that initiates UMP synthesis in Syrian hamster cells. Molecular and Cellular Biology. 2: 293-301. PMID 6125880  1
1979 Padgett RA, Wahl GM, Coleman PF, Stark GR. N-(Phosphonacetyl)-L-aspartate-resistant hamster cells overaccumulate a single mRNA coding for the multifunctional protein that catalyzes the first steps of UMP synthesis. The Journal of Biological Chemistry. 254: 974-80. PMID 762107  1
1979 Wahl GM, Padgett RA, Stark GR. Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells. The Journal of Biological Chemistry. 254: 8679-89. PMID 381311  1
1964 STARK GR, STEIN WH. ALKYLATION OF THE METHIONINE RESIDUES OF RIBONUCLEASE IN 8 M UREA. The Journal of Biological Chemistry. 239: 3755-61. PMID 14257603  1
1962 STARK GR, DAWSON CR. On the accessibility of sulfhydryl groups in ascorbic acid oxidase. The Journal of Biological Chemistry. 237: 712-6. PMID 13916312  1
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