Joseph M. Tager - Publications

Affiliations: 
University of Amsterdam, Amsterdam, Netherlands 
Area:
biochemistry

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1998 Wanders RJ, Tager JM. Lipid metabolism in peroxisomes in relation to human disease. Molecular Aspects of Medicine. 19: 69-154. PMID 9827430  1
1996 Groen AK, Elferink RP, Tager JM. Control analysis of biliary lipid secretion. Journal of Theoretical Biology. 182: 427-36. PMID 8944177 DOI: 10.1006/jtbi.1996.0183  1
1996 Tager JM, Moser HW, Barker PB, Barth PG, Boltshauser E, Campagnoni AT, Dawson G, DeVivo DC, Federico A, Fluharty AL, Gieselmann V, Hodes ME, Hurko O, Jaeken J, Kruse B, et al. The MRI suggests a leukodystrophy, but tests are negative - What should we do? Probing white-matter disorders Molecular and Chemical Neuropathology. 27: 1-106. PMID 8790669  1
1996 Wanders RJA, Tager JM. Chapter 6 Peroxisomal disorders Principles of Medical Biology. 3: 155-172. DOI: 10.1016/S1569-2582(05)80037-6  1
1994 Tager JM, Aerts JM, van den Bogert C, Wanders RJ. Signals on proteins, intracellular targeting and inborn errors of organellar metabolism. Journal of Inherited Metabolic Disease. 17: 459-69. PMID 7967496 DOI: 10.1007/BF00711361  1
1994 Wanders RJ, Barth PG, Schutgens RB, Tager JM. Clinical and biochemical characteristics of peroxisomal disorders: an update. European Journal of Pediatrics. 153: S44-8. PMID 7957386 DOI: 10.1007/BF02138777  1
1994 Wanders RJ, Dekker C, Hovarth VA, Schutgens RB, Tager JM, Van Laer P, Lecoutere D. Human alkyldihydroxyacetonephosphate synthase deficiency: a new peroxisomal disorder. Journal of Inherited Metabolic Disease. 17: 315-8. PMID 7807941 DOI: 10.1007/BF00711817  1
1993 van Weely S, Brandsma M, Strijland A, Tager JM, Aerts JM. Demonstration of the existence of a second, non-lysosomal glucocerebrosidase that is not deficient in Gaucher disease. Biochimica Et Biophysica Acta. 1181: 55-62. PMID 8457606 DOI: 10.1016/0925-4439(93)90090-N  1
1993 Kwekkeboom J, van Oosten M, de Boer M, van Alphen L, Mevissen ML, Lindhout E, Tager JM, de Groot C. An efficient procedure for the generation of human monoclonal antibodies based on activation of human B lymphocytes by a murine thymoma cell line. Journal of Immunological Methods. 160: 117-27. PMID 8450231 DOI: 10.1016/0022-1759(93)90015-Y  1
1993 van Weely S, van den Berg M, Barranger JA, Sa Miranda MC, Tager JM, Aerts JM. Role of pH in determining the cell-type-specific residual activity of glucocerebrosidase in type 1 Gaucher disease. The Journal of Clinical Investigation. 91: 1167-75. PMID 8450045 DOI: 10.1172/JCI116276  1
1993 Lindhout E, Mevissen ML, Kwekkeboom J, Tager JM, de Groot C. Direct evidence that human follicular dendritic cells (FDC) rescue germinal centre B cells from death by apoptosis. Clinical and Experimental Immunology. 91: 330-6. PMID 8428399  1
1993 Aerts JM, Van Weely S, Boot R, Hollak CE, Tager JM. Pathogenesis of lysosomal storage disorders as illustrated by Gaucher disease. Journal of Inherited Metabolic Disease. 16: 288-91. PMID 8411983 DOI: 10.1007/BF00710267  1
1993 Middelkoop E, Wiemer EA, Schoenmaker DE, Strijland A, Tager JM. Topology of catalase assembly in human skin fibroblasts. Biochimica Et Biophysica Acta. 1220: 15-20. PMID 8268239 DOI: 10.1016/0167-4889(93)90091-3  1
1993 Kwekkeboom J, De Boer M, Tager JM, De Groot C. CD40 plays an essential role in the activation of human B cells by murine EL4B5 cells. Immunology. 79: 439-44. PMID 7691726  1
1993 Wanders RJ, Schutgens RB, Barth PG, Tager JM, van den Bosch H. Postnatal diagnosis of peroxisomal disorders: a biochemical approach. Biochimie. 75: 269-79. PMID 7685190 DOI: 10.1016/0300-9084(93)90087-9  1
1992 Wiemer EA, Ofman R, Middelkoop E, de Boer M, Wanders RJ, Tager JM. Production and characterisation of monoclonal antibodies against native and disassembled human catalase. Journal of Immunological Methods. 151: 165-75. PMID 1629607 DOI: 10.1016/0022-1759(92)90115-A  1
1992 Heikoop JC, Wanders RJ, Strijland A, Purvis R, Schutgens RB, Tager JM. Genetic and biochemical heterogeneity in patients with the rhizomelic form of chondrodysplasia punctata--a complementation study. Human Genetics. 89: 439-44. PMID 1618493 DOI: 10.1007/BF00194319  1
1992 Kwekkeboom J, de Groot C, Tager JM. Efficient electric field-induced generation of hybridomas from human B lymphocytes without prior activation in vitro. Human Antibodies and Hybridomas. 3: 48-53. PMID 1576322  1
1992 Wanders RJ, van Roermund CW, Lageweg W, Jakobs BS, Schutgens RB, Nijenhuis AA, Tager JM. X-linked adrenoleukodystrophy: biochemical diagnosis and enzyme defect. Journal of Inherited Metabolic Disease. 15: 634-44. PMID 1528022 DOI: 10.1007/BF01799620  1
1992 Heikoop JC, van den Berg M, Strijland A, Weijers PJ, Just WW, Meijer AJ, Tager JM. Turnover of peroxisomal vesicles by autophagic proteolysis in cultured fibroblasts from Zellweger patients. European Journal of Cell Biology. 57: 165-71. PMID 1511694  1
1992 Wanders RJ, van Roermund CW, Denis S, Schutgens RB, Ijlst L, Tager JM. Molecular analysis of disorders of peroxisomal beta-oxidation. Progress in Clinical and Biological Research. 375: 507-19. PMID 1438395  1
1992 Wolvetang EJ, Tager JM, Wanders RJ. Latency of peroxisomal palmitoyl-CoA beta-oxidation in digitonin permeabilized fibroblasts: the effect of ATP on peroxisomal permeability. Progress in Clinical and Biological Research. 375: 223-9. PMID 1438367  1
1992 Wanders RJ, Schumacher H, Heikoop J, Schutgens RB, Tager JM. Human dihydroxyacetonephosphate acyltransferase deficiency: a new peroxisomal disorder. Journal of Inherited Metabolic Disease. 15: 389-91. PMID 1405476 DOI: 10.1007/BF02435984  1
1992 Wanders RJ, van Roermund CW, Brul S, Schutgens RB, Tager JM. Bifunctional enzyme deficiency: identification of a new type of peroxisomal disorder in a patient with an impairment in peroxisomal beta-oxidation of unknown aetiology by means of complementation analysis. Journal of Inherited Metabolic Disease. 15: 385-8. PMID 1357231 DOI: 10.1007/BF02435983  1
1992 van den Bosch H, Schutgens RB, Wanders RJ, Tager JM. Biochemistry of peroxisomes. Annual Review of Biochemistry. 61: 157-97. PMID 1353950 DOI: 10.1146/annurev.bi.61.070192.001105  1
1992 Heikoop JC, Ossendorp BC, Wanders RJ, Wirtz KW, Tager JM. Subcellular localisation and processing of non-specific lipid transfer protein are not aberrant in Rhizomelic Chondrodysplasia Punctata fibroblasts. Febs Letters. 299: 201-4. PMID 1347505 DOI: 10.1016/0014-5793(92)80247-E  1
1992 Klumperman J, Fransen JA, Tager JM, Ginsel LA. The cation-independent mannose 6-phosphate receptor is not involved in the polarized secretion of lysosomal alpha-glucosidase from Caco-2 cells. European Journal of Cell Biology. 57: 147-54. PMID 1324837  1
1992 Lombardo MC, van der Zwaan JW, Brul S, Tager JM. A procedure for selecting mammalian cells with an impairment in oxidative phosphorylation. Biochimica Et Biophysica Acta. 1138: 275-81. PMID 1314097 DOI: 10.1016/0925-4439(92)90004-7  1
1991 Lageweg W, Wanders RJ, Tager JM. Long-chain-acyl-CoA synthetase and very-long-chain-acyl-CoA synthetase activities in peroxisomes and microsomes from rat liver. An enzymological study. European Journal of Biochemistry / Febs. 196: 519-23. PMID 2007410  1
1991 Middelkoop E, Strijland A, Tager JM. Does aminotriazole inhibit import of catalase into peroxisomes by retarding unfolding? Febs Letters. 279: 79-82. PMID 1995347 DOI: 10.1016/0014-5793(91)80255-2  1
1991 Wanders RJ, Schutgens RB, van den Bosch H, Tager JM, Kleijer WJ. Prenatal diagnosis of inborn errors in peroxisomal beta-oxidation. Prenatal Diagnosis. 11: 253-61. PMID 1896411  1
1991 Rijnboutt S, Aerts HM, Geuze HJ, Tager JM, Strous GJ. Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells. The Journal of Biological Chemistry. 266: 4862-8. PMID 1848227  1
1991 Aerts JMFG, Miranda MCS, de Lacerda LW, van Weely S, Donker-Koopman W, Brouwer-Kelder B, Jansen DC, van Leeuwen M, Schram AW, Tsiapara A, Tager JM. The identification of type 1 Gaucher disease patients, asymptomatic cases and carriers in The Netherlands using urine samples: An evaluation Clinica Chimica Acta. 203: 349-361. PMID 1838035 DOI: 10.1016/0009-8981(91)90308-Y  1
1991 Van Weely S, Van Leeuwen MB, Jansen IDC, De Bruijn MAC, Brouwer-Kelder EM, Schram A, Sa Miranda MC, Barranger JA, Petersen EM, Goldblatt J, Stotz H, Schwarzmann G, Sandhoff K, Svennerholm L, Erikson A, ... Tager JM, et al. Clinical phenotype of Gaucher disease in relation to properties of mutant glucocerebrosidase in cultured fibroblasts Bba - Molecular Basis of Disease. 1096: 301-311. PMID 1829642 DOI: 10.1016/0925-4439(91)90066-I  1
1991 Lageweg W, Tager JM, Wanders RJ. Topography of very-long-chain-fatty-acid-activating activity in peroxisomes from rat liver. The Biochemical Journal. 276: 53-6. PMID 1828148  1
1991 Wanders RJ, Tager JM. Peroxisomal fatty acid beta-oxidation in relation to adrenoleukodystrophy. Developmental Neuroscience. 13: 262-6. PMID 1817031  1
1991 Lageweg W, Steen I, Tager JM, Wanders RJ. A fluorimetric assay for acyl-CoA synthetase activities. Analytical Biochemistry. 197: 384-8. PMID 1785692 DOI: 10.1016/0003-2697(91)90408-L  1
1991 Klumperman J, Fransen JA, Boekestijn TC, Oude Elferink RP, Matter K, Hauri HP, Tager JM, Ginsel LA. Biosynthesis and transport of lysosomal alpha-glucosidase in the human colon carcinoma cell line Caco-2: secretion from the apical surface. Journal of Cell Science. 100: 339-47. PMID 1757490  1
1991 Wiemer EA, Out M, Schelen A, Wanders RJ, Schutgens RB, Van den Bosch H, Tager JM. Phenotypic heterogeneity in cultured skin fibroblasts from patients with disorders of peroxisome biogenesis belonging to the same complementation group. Biochimica Et Biophysica Acta. 1097: 232-7. PMID 1718439 DOI: 10.1016/0925-4439(91)90041-7  1
1991 Mevissen ML, de Boer M, Tuin K, Tager JM, de Groot C. Identification of structural differences between different forms of interleukin-2 (IL-2) using anti-(human recombinant) IL-2 monoclonal antibodies. Cytokine. 3: 54-9. PMID 1715771 DOI: 10.1016/1043-4666(91)90010-B  1
1991 Ohashi T, Hong CM, Weiler S, Tomich JM, Aerts JM, Tager JM, Barranger JA. Characterization of human glucocerebrosidase from different mutant alleles. The Journal of Biological Chemistry. 266: 3661-7. PMID 1704891  1
1991 van Roermund CW, Brul S, Tager JM, Schutgens RB, Wanders RJ. Acyl-CoA oxidase, peroxisomal thiolase and dihydroxyacetone phosphate acyltransferase: aberrant subcellular localization in Zellweger syndrome. Journal of Inherited Metabolic Disease. 14: 152-64. PMID 1679469 DOI: 10.1007/BF01800588  1
1991 Bout A, Franse MM, Collins J, Blonden L, Tager JM, Benne R. Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient. Biochimica Et Biophysica Acta. 1090: 43-51. PMID 1679347 DOI: 10.1016/0167-4781(91)90035-K  1
1991 Heikoop JC, Van den Berg M, Strijland A, Weijers PJ, Schutgens RB, Just WW, Wanders RJ, Tager JM. Peroxisomes of normal morphology but deficient in 3-oxoacyl-CoA thiolase in rhizomelic chondrodysplasia punctata fibroblasts. Biochimica Et Biophysica Acta. 1097: 62-70. PMID 1677591  1
1991 Wolvetang EJ, Tager JM, Wanders RJ. Factors influencing the latency of the peroxisomal enzyme dihydroxyacetone-phosphate acyltransferase (DHAP-AT) in permeabilized human skin fibroblasts. Biochimica Et Biophysica Acta. 1095: 122-6. PMID 1657193 DOI: 10.1016/0167-4889(91)90074-8  1
1990 Wanders RJ, Ruiter J, van Roermund CW, Schutgens RB, Ofman R, Jurriaans S, Tager JM. Human liver L-alanine-glyoxylate aminotransferase: characteristics and activity in controls and hyperoxaluria type I patients using a simple spectrophotometric method. Clinica Chimica Acta; International Journal of Clinical Chemistry. 189: 139-44. PMID 2397596 DOI: 10.1016/0009-8981(90)90084-6  1
1990 Heikoop JC, van Roermund CW, Just WW, Ofman R, Schutgens RB, Heymans HS, Wanders RJ, Tager JM. Rhizomelic chondrodysplasia punctata. Deficiency of 3-oxoacyl-coenzyme A thiolase in peroxisomes and impaired processing of the enzyme. The Journal of Clinical Investigation. 86: 126-30. PMID 2365812 DOI: 10.1172/JCI114674  1
1990 Wanders RJ, van Roermund CW, Schelen A, Schutgens RB, Tager JM. Inborn errors of peroxisomal beta-oxidation: biochemical identification using enzymic and immunological methods. Progress in Clinical and Biological Research. 321: 559-67. PMID 2326311  1
1990 Wanders RJ, Heymans HS, Schutgens RB, van den Bosch H, Tager JM, Theil A. [Zellweger syndrome and other peroxisomal disorders: II. (Bio)chemical characteristics of a recently discovered group of diseases]. Nederlands Tijdschrift Voor Geneeskunde. 134: 639-42. PMID 2320167  1
1990 Hardeman D, Zomer HW, Schutgens RB, Tager JM, van den Bosch H. Effect of peroxisome proliferation on ether phospholipid biosynthesizing enzymes in rat liver. The International Journal of Biochemistry. 22: 1413-8. PMID 2276415 DOI: 10.1016/0020-711X(90)90231-Q  1
1990 Bout A, de Boer PA, Tager JM, Benne R, Moorman AF. Zonal distribution of peroxisomal 3-oxoacyl-CoA thiolase mRNA in liver from rats treated with di-(2-ethylhexyl)phthalate. Biochimica Et Biophysica Acta. 1055: 240-2. PMID 2265212 DOI: 10.1016/0167-4889(90)90039-G  1
1990 Wanders RJ, ten Brink HJ, van Roermund CW, Schutgens RB, Tager JM, Jakobs C. Identification of pristanoyl-CoA oxidase activity in human liver and its deficiency in the Zellweger syndrome. Biochemical and Biophysical Research Communications. 172: 490-5. PMID 2241949 DOI: 10.1016/0006-291X(90)90699-N  1
1990 Sa Miranda MC, Aerts JM, Pinto R, Fontes A, de Lacerda LW, van Weely S, Barranger J, Tager JM. Activity of glucocerebrosidase in extracts of different cell types from type 1 Gaucher disease patients. Clinical Genetics. 38: 218-27. PMID 2225530  1
1990 Aerts JM, Sa Miranda MC, Brouwer-Kelder EM, Van Weely S, Barranger JA, Tager JM. Conditions affecting the activity of glucocerebrosidase purified from spleens of control subjects and patients with type 1 Gaucher disease. Biochimica Et Biophysica Acta. 1041: 55-63. PMID 2223847 DOI: 10.1016/0167-4838(90)90122-V  1
1990 Aerts JM, Donker-Koopman WE, Brul S, Van Weely S, Sa Miranda MC, Barranger JA, Tager JM, Schram AW. Comparative study on glucocerebrosidase in spleens from patients with Gaucher disease. The Biochemical Journal. 269: 93-100. PMID 2198026  1
1990 Tager JM, Brul S, Wiemer EA, Strijland A, Van Driel R, Schutgens RB, Van den Bosch H, Wanders RJ, Westerveld A. Genetic relationship between the Zellweger syndrome and other peroxisomal disorders characterized by an impairment in the assembly of peroxisomes. Progress in Clinical and Biological Research. 321: 545-58. PMID 2183242  1
1990 Wolvetang EJ, Wanders RJ, Schutgens RB, Berden JA, Tager JM. Properties of the ATPase activity associated with peroxisome-enriched fractions from rat liver: comparison with mitochondrial F1F0-ATPase. Biochimica Et Biophysica Acta. 1035: 6-11. PMID 2166576 DOI: 10.1016/0304-4165(90)90166-T  1
1990 Van Beeumen JJ, Van Kuilenburg AB, Van Bun S, Van den Bogert C, Tager JM, Muijsers AO. Demonstration of two isoforms of subunit VIIa of cytochrome c oxidase from human skeletal muscle. Implications for mitochondrial myopathies. Febs Letters. 263: 213-6. PMID 2159420 DOI: 10.1016/0014-5793(90)81376-Y  1
1990 Van Weely S, Aerts JM, Van Leeuwen MB, Heikoop JC, Donker-Koopman WE, Barranger JA, Tager JM, Schram AW. Function of oligosaccharide modification in glucocerebrosidase, a membrane-associated lysosomal hydrolase. European Journal of Biochemistry / Febs. 191: 669-77. PMID 2143986 DOI: 10.1111/j.1432-1033.1990.tb19173.x  1
1990 Wolvetang EJ, Tager JM, Wanders RJ. Latency of the peroxisomal enzyme acyl-CoA:dihydroxyacetonephosphate acyltransferase in digitonin-permeabilized fibroblasts: the effect of ATP and ATPase inhibitors. Biochemical and Biophysical Research Communications. 170: 1135-43. PMID 2143898 DOI: 10.1016/0006-291X(90)90511-K  1
1990 Wanders RJ, van Roermund CW, Schelen A, Schutgens RB, Tager JM, Stephenson JB, Clayton PT. A bifunctional protein with deficient enzymic activity: identification of a new peroxisomal disorder using novel methods to measure the peroxisomal beta-oxidation enzyme activities. Journal of Inherited Metabolic Disease. 13: 375-9. PMID 2122104 DOI: 10.1007/BF01799399  1
1990 Wanders RJ, van Roermund CW, Schutgens RB, Barth PG, Heymans HS, van den Bosch H, Tager JM. The inborn errors of peroxisomal beta-oxidation: a review. Journal of Inherited Metabolic Disease. 13: 4-36. PMID 2109148 DOI: 10.1007/BF01799330  1
1990 Wanders RJ, Boltshauser E, Steinmann B, Spycher MA, Schutgens RB, van den Bosch H, Tager JM. Infantile phytanic acid storage disease, a disorder of peroxisome biogenesis: a case report. Journal of the Neurological Sciences. 98: 1-11. PMID 1700075 DOI: 10.1016/0022-510X(90)90177-O  1
1990 Heymans HS, Wanders RJ, Schutgens RB, van den Bosch H, Tager JM, Barth PG. [Zellweger syndrome and other peroxisomal disorders: I. Clinical characteristics of a recently discovered group of diseases]. Nederlands Tijdschrift Voor Geneeskunde. 134: 634-9. PMID 1690863  1
1990 Wanders RJA, Van Roermund CWT, Schelen A, Schutgens RBH, Van den Bosch H, Tager JM. X-linked adrenoleukodystrophy and other inborn errors of peroxisomal β-oxidation: Clinical and biochemical aspects Adrenoleukodystrophy and Other Peroxisomal Disorders. Clinical, Biochemical, Genetic and Therapeutic Aspects: Proceedings of the International Workshop. Ics898. 17-36.  1
1990 Tager JM, Brul S, Wiemer EAC, Heikoop JC, Middelkoop E, Bout A, Westerveld A, Wanders RJA. Peroxisomal disorders: An updating Adrenoleukodystrophy and Other Peroxisomal Disorders. Clinical, Biochemical, Genetic and Therapeutic Aspects: Proceedings of the International Workshop. Ics898. 3-15.  1
1989 van Duijn G, Langedijk JP, de Boer M, Tager JM. High yields of specific hybridomas obtained by electrofusion of murine lymphocytes immunized in vivo or in vitro. Experimental Cell Research. 183: 463-72. PMID 2767160 DOI: 10.1016/0014-4827(89)90405-9  1
1989 De Boer M, Ossendorp FA, Van Duijn G, Ten Voorde GH, Tager JM. Optimal conditions for the generation of monoclonal antibodies using primary immunisation of mouse splenocytes in vitro under serum-free conditions. Journal of Immunological Methods. 121: 253-60. PMID 2760468 DOI: 10.1016/0022-1759(89)90168-3  1
1989 Wiemer EA, Brul S, Just WW, Van Driel R, Brouwer-Kelder E, Van Den Berg M, Weijers PJ, Schutgens RB, Van Den Bosch H, Schram A. Presence of peroxisomal membrane proteins in liver and fibroblasts from patients with the Zellweger syndrome and related disorders: evidence for the existence of peroxisomal ghosts. European Journal of Cell Biology. 50: 407-17. PMID 2697558  1
1989 Oude Elferink RP, Fransen J, Klumperman J, Ginsel LA, Tager JM. Secretion of a precursor form of lysosomal alpha-glucosidase from the brush border of human kidney proximal tubule cells. European Journal of Cell Biology. 50: 299-303. PMID 2697557  1
1989 Wanders RJ, Barth PG, Schutgens RB, Van den Bosch H, Tager JM, Stroink H, Przyrembel H, Heymans HS. [X-linked adrenoleukodystrophy and other peroxisomal diseases caused by a failing peroxisomal beta-oxidation system: clinical expression, diagnosis and treatment]. Tijdschrift Voor Kindergeneeskunde. 57: 186-97. PMID 2683204  1
1989 Bout A, Hoovers JM, Bakker E, Mannens MM, Geurts van Kessel A, Westerveld A, Tager JM, Benne R. Assignment of the gene coding for human peroxisomal 3-oxoacyl-CoA thiolase (ACAA) to chromosome region 3p22----p23. Cytogenetics and Cell Genetics. 52: 147-50. PMID 2630187 DOI: 10.1159/000132861  1
1989 Wanders RJ, Romeyn GJ, Schutgens RB, Tager JM. L-pipecolate oxidase: a distinct peroxisomal enzyme in man. Biochemical and Biophysical Research Communications. 164: 550-5. PMID 2572224 DOI: 10.1016/0006-291X(89)91754-3  1
1989 Al BJ, Tiffany CW, Gomes de Mesquita DS, Moser HW, Tager JM, Schram AW. Properties of acid ceramidase from human spleen. Biochimica Et Biophysica Acta. 1004: 245-51. PMID 2526656 DOI: 10.1016/0005-2760(89)90274-9  1
1989 Robinson D, Tager JM. Hair root diagnosis of Fabry's disease. Journal of Inherited Metabolic Disease. 12: 491-2. PMID 2516183 DOI: 10.1007/BF01802051  1
1989 Wanders RJ, Wiemer EA, Brul S, Schutgens RB, van den Bosch H, Tager JM. Prenatal diagnosis of Zellweger syndrome by direct visualization of peroxisomes in chorionic villus fibroblasts by immunofluorescence microscopy. Journal of Inherited Metabolic Disease. 12: 301-4. PMID 2512431 DOI: 10.1007/BF03335405  1
1989 Schutgens RB, Schrakamp G, Wanders RJ, Heymans HS, Tager JM, van den Bosch H. Prenatal and perinatal diagnosis of peroxisomal disorders. Journal of Inherited Metabolic Disease. 12: 118-34. PMID 2509803 DOI: 10.1007/BF01799291  1
1989 Wanders RJA, Heymans HSA, Schutgens RBH, Van Den Bosch H, Tager JM. Biochemical investigations in peroxisomal disorders Journal of Clinical Chemistry and Clinical Biochemistry. 27: 303-304.  1
1989 Wanders RJA, Heymans HSA, Schutgens RBH, Barth PG, Van Den Bosch H, Tager JM. Peroxisomal diseases: Clinical and biochemical characteristics of a newly discovered group of hereditary diseases Tijdschrift Van De Nederlandse Vereniging Voor Klinische Chemie. 14: 152-164.  1
1988 Wanders RJ, Romeyn GJ, van Roermund CW, Schutgens RB, van den Bosch H, Tager JM. Identification of L-pipecolate oxidase in human liver and its deficiency in the Zellweger syndrome. Biochemical and Biophysical Research Communications. 154: 33-8. PMID 3395335 DOI: 10.1016/0006-291X(88)90645-6  1
1988 Aerts JM, Heikoop J, van Weely S, Donker-Koopman WE, Barranger JA, Tager JM, Schram AW. Characterization of glucocerebrosidase in peripheral blood cells and cultured blastoid cells. Experimental Cell Research. 177: 391-8. PMID 3391250 DOI: 10.1016/0014-4827(88)90472-7  1
1988 Wanders RJ, van Roermund CW, van Wijland MJ, Schutgens RB, van den Bosch H, Schram AW, Tager JM. Direct demonstration that the deficient oxidation of very long chain fatty acids in X-linked adrenoleukodystrophy is due to an impaired ability of peroxisomes to activate very long chain fatty acids. Biochemical and Biophysical Research Communications. 153: 618-24. PMID 3382393 DOI: 10.1016/S0006-291X(88)81140-9  1
1988 Schrakamp G, Schalkwijk CG, Schutgens RB, Wanders RJ, Tager JM, van den Bosch H. Plasmalogen biosynthesis in peroxisomal disorders: fatty alcohol versus alkylglycerol precursors. Journal of Lipid Research. 29: 325-34. PMID 3379344  1
1988 Brul S, Wiemer EA, Westerveld A, Strijland A, Wanders RJ, Schram AW, Heymans HS, Schutgens RB, Van den Bosch H, Tager JM. Kinetics of the assembly of peroxisomes after fusion of complementary cell lines from patients with the cerebro-hepato-renal (Zellweger) syndrome and related disorders. Biochemical and Biophysical Research Communications. 152: 1083-9. PMID 3377768 DOI: 10.1016/S0006-291X(88)80395-4  1
1988 Aerts JM, Schram AW, Strijland A, van Weely S, Jonsson LM, Tager JM, Sorrell SH, Ginns EI, Barranger JA, Murray GJ. Glucocerebrosidase, a lysosomal enzyme that does not undergo oligosaccharide phosphorylation. Biochimica Et Biophysica Acta. 964: 303-8. PMID 3349099 DOI: 10.1016/0304-4165(88)90030-X  1
1988 Willemsen R, van Dongen JM, Aerts JM, Schram AW, Tager JM, Goudsmit R, Reuser AJ. An immunoelectron microscopic study of glucocerebrosidase in type 1 Gaucher's disease spleen. Ultrastructural Pathology. 12: 471-8. PMID 3194992 DOI: 10.3109/01913128809032232  1
1988 Bout A, Teunissen Y, Hashimoto T, Benne R, Tager JM. Nucleotide sequence of human peroxisomal 3-oxoacyl-CoA thiolase. Nucleic Acids Research. 16: 10369. PMID 3194209  1
1988 Groen AK, Tager JM. Control analysis provides a simple means of understanding the control structure of a metabolic pathway. The Biochemical Journal. 253: 619-21. PMID 3178732  1
1988 Wanders RJ, van Roermund CW, Jurriaans S, Schutgens RB, Tager JM, van den Bosch H, Wolff ED, Przyrembel H, Berger R, Schaaphok FG. Diversity in residual alanine glyoxylate aminotransferase activity in hyperoxaluria type I: correlation with pyridoxine responsiveness. Journal of Inherited Metabolic Disease. 11: 208-11. PMID 3141704 DOI: 10.1007/BF01804237  1
1988 Wanders RJ, van Roermund CW, van Wijland MJ, Schutgens RB, Schram AW, Tager JM, van den Bosch H, Schalkwijk C. X-linked adrenoleukodystrophy: identification of the primary defect at the level of a deficient peroxisomal very long chain fatty acyl-CoA synthetase using a newly developed method for the isolation of peroxisomes from skin fibroblasts. Journal of Inherited Metabolic Disease. 11: 173-7. PMID 3141702 DOI: 10.1007/BF01804228  1
1988 Clayton PT, Lake BD, Hjelm M, Stephenson JB, Besley GT, Wanders RJ, Schram AW, Tager JM, Schutgens RB, Lawson AM. Bile acid analyses in "pseudo-Zellweger" syndrome; clues to the defect in peroxisomal beta-oxidation. Journal of Inherited Metabolic Disease. 11: 165-8. PMID 3141700 DOI: 10.1007/BF01804226  1
1988 Wanders RJ, van Roermund CW, van Wijland MJ, Schutgens RB, Tager JM, van den Bosch H, Thomas GH. Peroxisomes and peroxisomal functions in hyperpipecolic acidaemia. Journal of Inherited Metabolic Disease. 11: 161-4. PMID 3141699 DOI: 10.1007/BF01804225  1
1988 Sa Miranda MC, Aerts JM, Pinto RA, Magalhaes JA, Barranger JA, Tager JM, Schram AW. Heterogeneity in human acid beta-glucosidase revealed by cellulose-acetate electrophoresis. Biochimica Et Biophysica Acta. 965: 163-8. PMID 3130106 DOI: 10.1016/0304-4165(88)90052-9  1
1988 van den Bosch H, Schalkwijk CG, Schrakamp G, Wanders RJ, Schutgens RB, Schram AW, Tager JM. Aberration in de novo ether lipid biosynthesis in peroxisomal disorders. Progress in Clinical and Biological Research. 282: 139-50. PMID 3071794  1
1988 Fransen JA, Ginsel LA, Cambier PH, Klumperman J, Oude Elferink RP, Tager JM. Immunocytochemical demonstration of the lysosomal enzyme alpha-glucosidase in the brush border of human intestinal epithelial cells. European Journal of Cell Biology. 47: 72-80. PMID 3068058  1
1988 Wanders RJ, Heymans HS, Schutgens RB, Barth PG, van den Bosch H, Tager JM. Peroxisomal disorders in neurology. Journal of the Neurological Sciences. 88: 1-39. PMID 3066850 DOI: 10.1016/0022-510X(88)90203-1  1
1988 Wanders RJ, van Roermund CW, Schutgens RB, van den Bosch H, Tager JM. Impaired ability of peroxisomes to activate very-long-chain fatty acids in X-linked adrenoleukodystrophy. Lancet (London, England). 2: 170. PMID 2899227 DOI: 10.1016/S0140-6736(88)90729-5  1
1988 Poll-The BT, Roels F, Ogier H, Scotto J, Vamecq J, Schutgens RBH, Wanders RJA, Van Roermund CWT, Van Wijland MJA, Schram AW, Tager JM, Saudubray JM. A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy) American Journal of Human Genetics. 42: 422-434. PMID 2894756  1
1988 Sinjorgo KM, Hakvoort TB, Muijsers AO, Schram AW, Tager JM. Cytochrome c oxidase: organ-specific isoenzymes and deficiencies. Journal of Inherited Metabolic Disease. 11: 202-4. PMID 2846964 DOI: 10.1007/BF01804235  1
1988 De Boer M, Ten Voorde GH, Ossendorp FA, Van Duijn G, Tager JM. Requirements for the generation of memory B cells in vivo and their subsequent activation in vitro for the production of antigen-specific hybridomas. Journal of Immunological Methods. 113: 143-9. PMID 2459251 DOI: 10.1016/0022-1759(88)90390-0  1
1988 Brul S, Westerveld A, Strijland A, Wanders RJ, Schram AW, Heymans HS, Schutgens RB, van den Bosch H, Tager JM. Genetic heterogeneity in the cerebrohepatorenal (Zellweger) syndrome and other inherited disorders with a generalized impairment of peroxisomal functions. A study using complementation analysis. The Journal of Clinical Investigation. 81: 1710-5. PMID 2454948 DOI: 10.1172/JCI113510  1
1988 Wanders RJ, Heymans HS, Schutgens RB, Poll-Thé BT, Saudubray JM, Tager JM, Schrakamp G, van den Bosch H. Peroxisomal functions in classical Refsum's disease: comparison with the infantile form of Refsum's disease. Journal of the Neurological Sciences. 84: 147-55. PMID 2454298 DOI: 10.1016/0022-510X(88)90120-7  1
1987 Aerts JM, Donker-Koopman WE, van Laar C, Brul S, Murray GJ, Wenger DA, Barranger JA, Tager JM, Schram AW. Relationship between the two immunologically distinguishable forms of glucocerebrosidase in tissue extracts. European Journal of Biochemistry / Febs. 163: 583-9. PMID 3830174 DOI: 10.1111/j.1432-1033.1987.tb10907.x  1
1987 Wanders RJ, Strijland A, van Roermund CW, van den Bosch H, Schutgens RB, Tager JM, Schram AW. Catalase in cultured skin fibroblasts from patients with the cerebro-hepato-renal (Zellweger) syndrome: normal maturation in peroxisome-deficient cells. Biochimica Et Biophysica Acta. 923: 478-82. PMID 3828388 DOI: 10.1016/0304-4165(87)90057-2  1
1987 Willemsen R, von Dongen JM, Ginns EI, Sips HJ, Schram AW, Tager JM, Barranger JA, Reuser AJJ. Ultrastructural localization of glucocerebrosidase in cultured Gaucher's disease fibroblasts by immunocytochemistry Journal of Neurology. 234: 44-51. PMID 3819786 DOI: 10.1007/BF00314009  1
1987 Wanders RJ, Schutgens RB, Schrakamp G, Tager JM, Van den Bosch H, Moser AB, Moser HW. Neonatal adrenoleukodystrophy. Impaired plasmalogen biosynthesis and peroxisomal beta-oxidation due to a deficiency of catalase-containing particles (peroxisomes) in cultured skin fibroblasts. Journal of the Neurological Sciences. 77: 331-40. PMID 3819771 DOI: 10.1016/0022-510X(87)90132-8  1
1987 de Vries AC, Schram AW, van den Berg M, Tager JM, Batenburg JJ, van Golde LM. An improved procedure for the isolation of lamellar bodies from human lung. Lamellar bodies free of lysosomes contain a spectrum of lysosomal-type hydrolases. Biochimica Et Biophysica Acta. 922: 259-69. PMID 3689811 DOI: 10.1016/0005-2760(87)90048-8  1
1987 de Boer M, Ossendorp FA, Al BJ, Hilgers J, de Vijlder JJ, Tager JM. Production of monoclonal antibodies to thyroglobulin by in vitro immunization with a free synthetic peptide. Molecular Immunology. 24: 1081-6. PMID 3683404 DOI: 10.1016/0161-5890(87)90076-9  1
1987 Wanders RJ, van Roermund CW, van Wijland MJ, Schutgens RB, Heikoop J, van den Bosch H, Schram AW, Tager JM. Peroxisomal fatty acid beta-oxidation in relation to the accumulation of very long chain fatty acids in cultured skin fibroblasts from patients with Zellweger syndrome and other peroxisomal disorders. The Journal of Clinical Investigation. 80: 1778-83. PMID 3680527 DOI: 10.1172/JCI113271  1
1987 Wanders RJ, van Roermund CW, van Wijland MJ, Nijenhuis AA, Tromp A, Schutgens RB, Brouwer-Kelder EM, Schram AW, Tager JM, van den Bosch H. X-linked adrenoleukodystrophy: defective peroxisomal oxidation of very long chain fatty acids but not of very long chain fatty acyl-CoA esters. Clinica Chimica Acta; International Journal of Clinical Chemistry. 165: 321-9. PMID 3652454 DOI: 10.1016/0009-8981(87)90177-X  1
1987 Wanders RJ, van Roermund CW, Westra R, Schutgens RB, van der Ende MA, Tager JM, Monnens LA, Baadenhuysen H, Govaerts L, Przyrembel H. Alanine glyoxylate aminotransferase and the urinary excretion of oxalate and glycollate in hyperoxaluria type I and the Zellweger syndrome. Clinica Chimica Acta; International Journal of Clinical Chemistry. 165: 311-9. PMID 3652453 DOI: 10.1016/0009-8981(87)90176-8  1
1987 Wanders RJ, van Wijland MJ, van Roermund CW, Schutgens RB, van den Bosch H, Tager JM, Nijenhuis A, Tromp A. Prenatal diagnosis of Zellweger syndrome by measurement of very long chain fatty acid (C26:0) beta-oxidation in cultured chorionic villous fibroblasts: implications for early diagnosis of other peroxisomal disorders. Clinica Chimica Acta; International Journal of Clinical Chemistry. 165: 303-10. PMID 3652452 DOI: 10.1016/0009-8981(87)90175-6  1
1987 Wanders RJ, Barth PG, van Roermund CW, Ofman R, Wolterman R, Schutgens RB, Tager JM, van den Bosch H, Bolhuis PA. Peroxisomes and peroxisomal functions in muscle. Studies with muscle cells from controls and a patient with the cerebro-hepato-renal (Zellweger) syndrome. Experimental Cell Research. 170: 147-52. PMID 3569428 DOI: 10.1016/0014-4827(87)90123-6  1
1987 Jonsson LM, Murray GJ, Sorrell SH, Strijland A, Aerts JF, Ginns EI, Barranger JA, Tager JM, Schram AW. Biosynthesis and maturation of glucocerebrosidase in Gaucher fibroblasts. European Journal of Biochemistry / Febs. 164: 171-9. PMID 3549301 DOI: 10.1111/j.1432-1033.1987.tb11008.x  1
1987 Mutsaers JH, Van Halbeek H, Vliegenthart JF, Tager JM, Reuser AJ, Kroos M, Galjaard H. Determination of the structure of the carbohydrate chains of acid alpha-glucosidase from human placenta. Biochimica Et Biophysica Acta. 911: 244-51. PMID 3542049 DOI: 10.1016/0167-4838(87)90014-8  1
1987 Schutgens RBH, Wanders RJA, Nijenhuis A, Van den Hoek CM, Heymans HSA, Schrakamp G, Bleeker-Wagemakers EM, Delleman JW, Schram AW, Tager JM, Van den Bosch H. Genetic diseases caused by peroxisomal dysfunction. New findings in clinical and biochemical studies Enzyme. 38: 161-176. PMID 3440444  1
1987 de Boer M, Admiraal P, Kok K, Ossendorp FA, de Vijlder JJ, Tager JM. Characterization of five monoclonal antibodies obtained after immunization in vitro with a synthetic 19-amino acid peptide of thyroglobulin. Hybridoma. 6: 655-62. PMID 3436626  1
1987 de Boer M, Ossendorp FA, Bruning PF, Tager JM. Direct evidence for a primary immune response of murine B-lymphocytes after in vitro immunization of dissociated splenocytes. Hybridoma. 6: 253-8. PMID 3298001  1
1987 Tager JM, Oude Elferink RPJ, Reuser A, Kroos M, Ginsel LA, Fransen JAM, Klumperman J. α-Glucosidase deficiency (Pompe's disease) Enzyme. 38: 280-285. PMID 3126044  1
1987 Schutgens RBH, Wanders RJA, Heymans HSA, Schram AW, Tager JM, Schrakamp G, van den Bosch H. Zellweger syndrome: Biochemical procedures in diagnosis, prevention and treatment Journal of Inherited Metabolic Disease. 10: 33-45. PMID 3119940 DOI: 10.1007/BF01812845  1
1987 Tager JM. Inborn errors of cellular organelles: an overview Journal of Inherited Metabolic Disease. 10: 3-10. PMID 3119939 DOI: 10.1007/BF01812842  1
1987 Reuser AJ, Kroos M, Willemsen R, Swallow D, Tager JM, Galjaard H. Clinical diversity in glycogenosis type II. Biosynthesis and in situ localization of acid alpha-glucosidase in mutant fibroblasts. The Journal of Clinical Investigation. 79: 1689-99. PMID 3108320 DOI: 10.1172/JCI113008  1
1987 Wanders RJ, van Roermund CW, van Wijland MJ, Schutgens RB, Schram AW, van den Bosch H, Tager JM. Studies on the peroxisomal oxidation of palmitate and lignocerate in rat liver. Biochimica Et Biophysica Acta. 919: 21-5. PMID 2952173 DOI: 10.1016/0005-2760(87)90213-X  1
1987 Schram AW, Goldfischer S, van Roermund CW, Brouwer-Kelder EM, Collins J, Hashimoto T, Heymans HS, van den Bosch H, Schutgens RB, Tager JM. Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency. Proceedings of the National Academy of Sciences of the United States of America. 84: 2494-6. PMID 2882519 DOI: 10.1073/pnas.84.8.2494  1
1987 Quintern LE, Weitz G, Nehrkorn H, Tager JM, Schram AW, Sandhoff K. Acid sphingomyelinase from human urine: purification and characterization. Biochimica Et Biophysica Acta. 922: 323-36. PMID 2825797 DOI: 10.1016/0005-2760(87)90055-5  1
1987 Poll-The BT, Saudubray JM, Ogier HAM, Odièvre M, Scotto JM, Monnens L, Govaerts LCP, Roels F, Cornelis A, Schutgens RBH, Wanders RJA, Schram AW, Tager JM. Infantile Refsum disease: an inherited peroxisomal disorder - Comparison with Zellweger syndrome and neonatal adrenoleukodystrophy European Journal of Pediatrics. 146: 477-483. PMID 2445576 DOI: 10.1007/BF00441598  1
1987 Wanders RJ, van Roermund CW, van Wijland MJ, Heikoop J, Schutgens RB, Schram AW, Tager JM, van den Bosch H, Poll-Thé BT, Saudubray JM. Peroxisomal very long-chain fatty acid beta-oxidation in human skin fibroblasts: activity in Zellweger syndrome and other peroxisomal disorders. Clinica Chimica Acta; International Journal of Clinical Chemistry. 166: 255-63. PMID 2441904 DOI: 10.1016/0009-8981(87)90428-1  1
1987 Wanders RJA, Smit W, Heymans HSA, Schutgens RBH, Barth PG, Schierbeek H, Smit GPA, Berger R, Przyrembel H, Eggelte TA, Tager JM, Maaswinkel-Mooy PD, Peters ACB, Monnens LAH, Bakkeren JAJM, et al. Age-related accumulation of phytanic acid in plasma from patients with the cerebro-hepato-renal (Zellweger) syndrome Clinica Chimica Acta. 166: 45-56. PMID 2440622 DOI: 10.1016/0009-8981(87)90193-8  1
1987 Poll-The BT, Saudubray JM, Rocchiccioli F, Scotto J, Roels F, Boue J, Ogier H, Dumez Y, Wanders RJA, Schutgens RBH, Schram AW, Tager JM. Prenatal diagnosis and confirmation of Infantile Refsum's disease Journal of Inherited Metabolic Disease. 10: 229-232. DOI: 10.1007/BF01811412  1
1987 Wanders RJA, Schutgens RBH, Schrakamp G, van den Bosch H, Tager JM, Moser AB, Moser HW. Generalized loss of peroxisomal functions in neonatal adrenoleukodystrophy: Implications for Pre- and postnatal detection and relationship to X-linked adrenoleukodystrophy Journal of Inherited Metabolic Disease. 10: 225-228. DOI: 10.1007/BF01811411  1
1987 Wanders RJA, Van Roermund CWT, Van Wijland MJA, Heikoop J, Van den Put A, Bentlage P, Meijboom E, Tager JM, Schram AW, Van den Bosch H, Schutgens RBH. Peroxisomal fatty acid β-oxidation in human skin fibroblasts: X-linked adrenoleukodystrophy, a peroxisomal very long chain fatty acyl-CoA synthetase deficiency? Journal of Inherited Metabolic Disease. 10: 220-224. DOI: 10.1007/BF01811410  1
1987 Schram AW, Goldfischer S, Wanders RJA, Brouwer-Kelder EM, van Roermund CWT, Collins J, Hashimoto T, Heymans HSA, Schutgens RBH, van den Bosch H, Tager JM. A genetic disorder due to the deficiency of the peroxisomal β-oxidation enzyme 3-oxoacyl-CoA thiolase Journal of Inherited Metabolic Disease. 10: 214-216. DOI: 10.1007/BF01811408  1
1987 Wanders RJA, Barth PG, Schutgens RBH, van Roemund CWT, Ofman R, Tager JM, Wolterman R, Bolhuis PA. Cultured human muscle cells from controls and a Zellweger patient: Study on peroxisomes and peroxisomal functions Journal of Inherited Metabolic Disease. 10: 207-210. DOI: 10.1007/BF01811406  1
1986 Leverve XM, Verhoeven AJ, Groen AK, Meijer AJ, Tager JM. The malate/aspartate shuttle and pyruvate kinase as targets involved in the stimulation of gluconeogenesis by phenylephrine European Journal of Biochemistry. 155: 551-556. PMID 3956499  1
1986 Groen AK, Van Roermund CWT, Vervoorn RC, Tager JM. Control of gluconeogenesis in rat liver cells. Flux control coefficients of the enzymes in the gluconeogenic pathway in the absence and presence of glucagon Biochemical Journal. 237: 379-389. PMID 3800895  1
1986 Aerts JMFG, Donker-Koopman WE, Koot M, Murray GJ, Barranger JA, Tager JM, Schram AW. Comparison of the properties of a soluble form of glucocerebrosidase from human urine with those of the membrane-associated tissue enzyme Bba - Biomembranes. 863: 63-70. PMID 3778913 DOI: 10.1016/0005-2736(86)90387-1  1
1986 Wanders RJA, Schrakamp G, van den Bosch H, Tager JM, Schutgens RBH. A prenatal test for the cerebro-hepato-renal (Zellweger) syndrome by demonstration of the absence of catalase-containing particles (peroxisomes) in cultured amniotic fluid cells European Journal of Pediatrics. 145: 136-138. PMID 3732317 DOI: 10.1007/BF00441876  1
1986 Aerts JMFG, Donker-Koopman WE, Murray GJ, Barranger JA, Tager JM, Schram A. A procedure for the rapid purification in high yield of human glucocerebrosidase using immunoaffinity chromatography with monoclonal antibodies Analytical Biochemistry. 154: 655-663. PMID 3728974 DOI: 10.1016/0003-2697(86)90043-6  1
1986 Schutgens RBH, Romeyn GJ, Ofman R, van den Bosch H, Tager JM, Wanders RJA. Acyl-CoA: dihydroxyacetone phosphate acyltransferase in human skin fibroblasts: study of its properties using a new assay method Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 879: 286-291. PMID 3535897 DOI: 10.1016/0005-2760(86)90217-1  1
1986 de Vries ACJ, Schram AW, Tager JM, Batenburg JJ, van Golde LMG. Genetic relationship between lysosomal and lamellar body-specific α-glucosidases in human lung Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 878: 288-291. PMID 3530334 DOI: 10.1016/0005-2760(86)90159-1  1
1986 Verhoeven AJ, van Roermund CW, Plomp PJ, Wanders RJ, Groen AK, Tager JM. Regulation of mitochondrial respiration in liver Advances in Experimental Medicine and Biology. 194: 241-254. PMID 3529860  1
1986 Oude Elferink RPJ, van Doorn-Van Wakeren J, Hendriks T, Strijland A, Tager JM. Transport and processing of endocytosed lysosomal α-glucosidase in cultured human skin fibroblasts European Journal of Biochemistry. 158: 339-344. PMID 3525157  1
1986 Schutgens RBH, Heymans HSA, Wanders RJA, Bosch Hvd, Tager JM. Peroxisomal disorders: A newly recognised group of genetic diseases European Journal of Pediatrics. 144: 430-440. PMID 3514227 DOI: 10.1007/BF00441734  1
1986 Ossendorp FA, De Boer M, J.M. Al B, Hilgers J, Bruning PF, Tager JM. Production of murine monoclonal antibodies against human thyroglobulin using an in vitro immunization procedure in serum-free medium Journal of Immunological Methods. 91: 257-264. PMID 3488350 DOI: 10.1016/0022-1759(86)90487-4  1
1986 Wanders RJA, Purvis YR, Heymans HSA, Bakkeren JAJM, Parmentier GG, van Eldere J, Eyssen H, van den Bosch H, Tager JM, Schutgens RBH. Age-related differences in plasmalogen content of erythrocytes from patients with the cerebro-hepato-renal (Zellweger) syndrome: Implications for postnatal detection of the disease Journal of Inherited Metabolic Disease. 9: 335-342. PMID 3104670 DOI: 10.1007/BF01800482  1
1986 Aerts JM, Brul S, Donker-Koopman WE, van Weely S, Murray GJ, Barranger JA, Tager JM, Schram AW. Efficient routing of glucocerebrosidase to lysosomes requires complex oligosaccharide chain formation. Biochemical and Biophysical Research Communications. 141: 452-8. PMID 2948505 DOI: 10.1016/S0006-291X(86)80194-2  1
1986 Wanders RJA, van Roermund CWT, de Vries CT, van den Bosch H, Schrakamp G, Tager JM, Schram A, Schutgens RBH. Peroxisomal β-oxidation of palmitoyl-CoA in human liver homogenates and its deficiency in the cerebro-hepato-renal (Zellweger) syndrome Clinica Chimica Acta. 159: 1-10. PMID 2944672 DOI: 10.1016/0009-8981(86)90160-9  1
1986 Aerts JMFG, Donker-Koopman WE, Koot M, Barranger JA, Tager JM, Schram A. Deficient activity of glucocerebrosidase in urine from patients with type 1 Gaucher disease Clinica Chimica Acta. 158: 155-163. PMID 2943536 DOI: 10.1016/0009-8981(86)90231-7  1
1986 Wanders RJA, Schutgens RBH, Schrakamp G, van den Bosch H, Tager JM, Schram AW, Hashimoto T, Poll-Thé BT, Saudubrau JM. Infantile Refsum disease: deficiency of catalase-containing particles (peroxisomes), alkyldihydroxyacetone phosphate synthase and peroxisomal β-oxidation enzyme proteins European Journal of Pediatrics. 145: 172-175. PMID 2429839 DOI: 10.1007/BF00446057  1
1986 Schram AW, Strijland A, Hashimoto T, Wanders RJ, Schutgens RB, van den Bosch H, Tager JM. Biosynthesis and maturation of peroxisomal β-oxidation enzymes in fibroblasts in relation to the Zellweger syndrome and infantile Refsum disease Proceedings of the National Academy of Sciences of the United States of America. 83: 6156-6158. PMID 2426710 DOI: 10.1073/pnas.83.16.6156  1
1986 Wanders RJA, Schutgens RBH, Schrakamp G, van den Bosch H, Tager JM, Poll-Thé BT, Saudubray JM. Deficiency of dihydroxyacetonephosphate acyltransferase and catalase-containing particles in patients with infantile refsum's disease Journal of Inherited Metabolic Disease. 9: 325-328. DOI: 10.1007/BF01799742  1
1986 Wanders RJA, Schrakamp G, van den Bosch H, Tager JM, Moser HW, Moser AE, Aubourg P, Kleijer WJ, Schutgens RBH. Pre- and postnatal diagnosis of the cerebrohepato-renal (Zellweger) syndrome via a simple method directly demonstrating the presence of absence of peroxisomes in cultured skin fibroblasts, amniocytes or chorionic villi fibroblasts Journal of Inherited Metabolic Disease. 9: 317-320. DOI: 10.1007/BF01799740  1
1985 Schutgens RB, Schrakamp G, Wanders RJ, Heymans HS, Moser HW, Moser AE, Tager JM, Bosch HV, Aubourg P. The cerebro-hepato-renal (Zellweger) syndrome: prenatal detection based on impaired biosynthesis of plasmalogens. Prenatal Diagnosis. 5: 337-44. PMID 4070172 DOI: 10.1002/pd.1970050506  1
1985 Plomp PJAM, van Roermund CWT, Groen AK, Meijer AJ, Tager JM. Mechanism of the stimulation of respiration by fatty acids in rat liver Febs Letters. 193: 243-246. PMID 4065340 DOI: 10.1016/0014-5793(85)80161-7  1
1985 Wanders RJA, van Weringh G, Schrakamp G, Tager JM, van den Bosch H, Schutgens RBH. Deficiency of acyl-CoA: dihydroxyacetone phosphate acyltransferase in thrombocytes of Zellweger patients: a simple postnatal diagnostic test Clinica Chimica Acta. 151: 217-221. PMID 4053381 DOI: 10.1016/0009-8981(85)90083-X  1
1985 Groen AK, Verhoeven AJ, van Roermund CW, Tager JM. Application of control analysis in studies of regulation of intermediary metabolism Biomedica Biochimica Acta. 44: 943-952. PMID 4038288  1
1985 Schrakamp G, Roosenboom CFP, Schutgens RBH, Wanders RJ, Heymans HS, Tager JM, van den Bosch H. Alkyl dihydroxyacetone phosphate synthase in human fibroblasts and its deficiency in Zellweger syndrome Journal of Lipid Research. 26: 867-873. PMID 4031664  1
1985 Aerts JMFG, Donker-Koopman WE, van Der Vliet MK, Jonsson LM, Ginns EI, Murray GJ, Barranger JA, Tager JM, Schram AW. The occurrence of two immunologically distinguishable β-glucocerebrosidases in human spleen European Journal of Biochemistry. 150: 565-574. PMID 4018098 DOI: 10.1111/j.1432-1033.1985.tb09058.x  1
1985 Tager JM, Ten Harmsen Van Der Beek WA, Wanders RJA, Hashimoto T, Heymans HSA, Van Den Bosch H, Schutgens RBH, Schram A. Peroxisomal β-oxidation enzyme proteins in the Zellweger syndrome Biochemical and Biophysical Research Communications. 126: 1269-1275. PMID 3977916 DOI: 10.1016/0006-291X(85)90322-5  1
1985 Verhoeven AJ, Kamer P, Groen AK, Tager JM. Effects of thyroid hormone on mitochondrial oxidative phosphorylation Biochemical Journal. 226: 183-192. PMID 3977864  1
1985 Schrakamp G, Schutgens RBH, Wanders RJA, Heymans HSA, Tager JM, Van den Bosch H. The cerebro-hepato-renal (Zellweger) syndrome. Impaired de novo biosynthesis of plasmalogens in cultured skin fibroblasts Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 833: 170-174. PMID 3967038 DOI: 10.1016/0005-2760(85)90266-8  1
1985 de Vries ACJ, Schram A, Tager JM, Batenburg JJ, van Golde LMG. A specific acid α-glucosidase in lamellar bodies of the human lung Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 837: 230-238. PMID 3933564 DOI: 10.1016/0005-2760(85)90046-3  1
1985 Oude Elferink RPJ, van Doorn-Van Wakeren J, Strijland A, Reuser AJ, Tager JM. Biosynthesis and intracellular transport of α-glucosidase and cathepsin D in normal and mutant human fibroblasts European Journal of Biochemistry. 153: 55-63. PMID 3905406 DOI: 10.1111/j.1432-1033.1985.tb09266.x  1
1985 Hakvoort TBM, Veyron P, Muilerman HG, Van Dijk W, Tager JM. Identification of denatured enzyme proteins in sodium dodecyl sulfate polyacrylamide gels Biochemical Medicine. 33: 327-333. PMID 3893424 DOI: 10.1016/0006-2944(85)90007-9  1
1985 Freedland RA, Meijer AJ, Tager JM. Nutritional influences on the distribution of the urea cycle: Intermediates in isolated hepatocytes Federation Proceedings. 44: 2453-2457. PMID 3886433  1
1985 Reuser AJJ, Kroos M, Oude Elferink RPJ, Tager JM. Defects in synthesis, phosphorylation, and maturation of acid α-glucosidase in glycogenosis type II Journal of Biological Chemistry. 260: 8336-8341. PMID 3159730  1
1985 Driessen M, Weitz G, Brouwer-Kelder EM, Donker-Koopman WE, Bastiaannet J, Sandhoff K, Barranger JA, Tager JM, Schram A. The effect of detergents on immunoprecipitability of lysosomal sphingomyelinase Bba - General Subjects. 841: 97-102. PMID 2990569 DOI: 10.1016/0304-4165(85)90278-8  1
1985 Weitz G, Driessen M, Brouwer-Kelder EM, Sandhoff K, Barranger JA, Tager JM, Schram A. Soluble sphingomyelinase from human urine as antigen for obtaining anti-sphingomyelinase antibodies Bba - General Subjects. 838: 92-97. PMID 2981569 DOI: 10.1016/0304-4165(85)90254-5  1
1985 van Dongen JM, Willemsen R, Ginns EI, Sips HJ, Tager JM, Barranger JA, Reuser AJ. The subcellular localization of soluble and membrane-bound lysosomal enzymes in I-cell fibroblasts: A comparative immunocytochemical study European Journal of Cell Biology. 39: 179-189. PMID 2935398  1
1985 Haussinger D, Soboll S, Meijer AJ, Gerok W, Tager JM, Sies H. Role of plasma membrane transport in hepatic glutamine metabolism European Journal of Biochemistry. 152: 597-603. PMID 2865140 DOI: 10.1111/j.1432-1033.1985.tb09237.x  1
1985 Wanders RJA, Schutgens RBH, Tager JM. Peroxisomal matrix enzymes in zellweger syndrome: Activity and subcellular localization in liver Journal of Inherited Metabolic Disease. 8: 151-152. PMID 2864474 DOI: 10.1007/BF01811504  1
1985 Leverve XM, Groen AK, Verhoeven AJ, Tager JM. Kinetic analysis of short-term effects of α-agonists on gluconeogenesis in isolated rat hepatocytes Febs Letters. 181: 43-46. PMID 2857658 DOI: 10.1016/0014-5793(85)81110-8  1
1985 Tager JM. Biosynthesis and deficiency of lysosomal enzymes Trends in Biochemical Sciences. 10: 324-326. DOI: 10.1016/0968-0004(85)90174-4  1
1985 Burns JA, Cornish-Bowden A, Groen AK, Heinrich R, Kacser H, Porteous JW, Rapoport SM, Rapoport TA, Stucki JW, Tager JM, Wanders RJA, Westerhoff HV. Control analysis of metabolic systems Trends in Biochemical Sciences. 10: 16. DOI: 10.1016/0968-0004(85)90008-8  1
1984 Tager JM, Jonsson LVM, Aerts JMFG, Elferink RP, Schram AW, Erickson AH, Barranger JA. Metabolic consequences of genetic defects in lysosomes Biochemical Society Transactions. 12: 902-905. PMID 6530036  1
1984 Wanders RJA, Kos M, Roest B, Meijer AJ, Schrakamp G, Heymans HSA, Tegelaers WHH, van den Bosch H, Schutgens RBH, Tager JM. Activity of peroxisomal enzymes and intracellular distribution of catalase in Zellweger syndrome Biochemical and Biophysical Research Communications. 123: 1054-1061. PMID 6148939 DOI: 10.1016/S0006-291X(84)80240-5  1
1984 Schram AW, Dreissen M, Bastiaannet J, Donker-Koopman WE, Brouwer-Kelder EM, Weitz G, Barranger JA, Sandhoff K, Tager JM. Immunological studies on lysosomal sphingomyelinase: Identification of a 28 000-Da component deficient in urine from patients with Niemann-Pick disease types A and B Bioscience Reports. 4: 1051-1057. PMID 6099155 DOI: 10.1007/BF01116698  1
1984 Wanders RJA, van den Berg GB, Tager JM. A re-evaluation of conditions required for an accurate estimation of the extramitochondrial ATP ADP ratio in isolated rat-liver mitochondria Bba - Bioenergetics. 767: 113-119. PMID 6091749 DOI: 10.1016/0005-2728(84)90085-9  1
1984 Wanders RJ, Groen AK, Van Roermund CW, Tager JM. Factors determining the relative contribution of the adenine-nucleotide translocator and the ADP-regenerating system to the control of oxidative phosphorylation in isolated rat-liver mitochondria European Journal of Biochemistry. 142: 417-424. PMID 6086353  1
1984 Schram AW, Weitz G, Driessen M, Brouwer-Kelder EM, Sandhoff K, Barranger JA, Tager JM. Immunological properties of urinary sphingomyelinase Biochemical Society Transactions. 12: 1027-1028.  1
1984 Oude Elferink RPJ, Hendriks T, Strijland A, Brouwer-Kelder EM, Damsma O, Hilkens J, Hilgers J, Tager JM. Differential effects of leupeptin on the maturation of lysosomal α-glucosidase Biochemical Society Transactions. 12: 1028-1029.  1
1983 Barneveld RA, Keijzer W, Tegelaers FP, Ginns EI, Geurts van Kessel A, Brady RO, Barranger JA, Tager JM, Galjaard H, Westerveld A, Reuser AJ. Assignment of the gene coding for human beta-glucocerebrosidase to the region q21-q31 of chromosome 1 using monoclonal antibodies. Human Genetics. 64: 227-31. PMID 6885065 DOI: 10.1007/BF00279398  1
1983 Ginns EI, Tegelaers FP, Barneveld R, Galjaard H, Reuser AJ, Brady RO, Tager JM, Barranger JA. Determination of Gaucher's disease phenotypes with monoclonal antibody. Clinica Chimica Acta; International Journal of Clinical Chemistry. 131: 283-7. PMID 6883722 DOI: 10.1016/0009-8981(83)90097-9  1
1983 Wanders RJA, Meijer AJ, Groen AK, Tager JM. Bicarbonate and the pathway of glutamate oxidation in isolated rat-liver mitochondria European Journal of Biochemistry. 133: 245-254. PMID 6852031  1
1983 Gankema HS, Groen AK, Wanders RJA, Tager JM. Measurement of binding of adenine nucleotides and phosphate to cytosolic proteins in permeabilized rat-liver cells European Journal of Biochemistry. 131: 447-451. PMID 6832160  1
1983 Groen AK, Vervoorn RC, Van der Meer R, Tager JM. Control of gluconeogenesis in rat liver cells. I. Kinetics of the individual enzymes and the effect of glucagon Journal of Biological Chemistry. 258: 14346-14353. PMID 6643485  1
1983 Oude Elferink RPJ, Harms E, Strijland A, Tager JM. The intralysosomal pH in cultured human skin fibroblasts in relation to cystine accumulation in patients with cystinosis Biochemical and Biophysical Research Communications. 116: 154-161. PMID 6639653 DOI: 10.1016/0006-291X(83)90394-7  1
1983 Ginns EI, Erickson A, Tegelaers FP, Barneveld R, Reuser AJ, Brady RO, Tager JM, Barranger JA. Isozymes of beta-glucosidase: determination of Gaucher's disease phenotypes. Isozymes. 11: 83-93. PMID 6417048  1
1983 Tager JM, Elferink RO, Brouwer-Kelder B, Strijland A, Hilkens J, Reuser A, Kroos M, Surya I, Paape M, Hilgers J. Multiple molecular forms of human acid alpha-glucosidase Isozymes. 7: 101-112. PMID 6350217  1
1983 Tager JM, Wanders RJA, Groen AK, Kunz W, Bohnensack R, Küster U, Letko G, Böhme G, Duszynski J, Wojtczak L. Control of mitochondrial respiration Febs Letters. 151: 1-9. PMID 6337871 DOI: 10.1016/0014-5793(83)80330-5  1
1983 Barneveld RA, Tegelaers FP, Ginns EI, Visser P, Laanen EA, Brady RO, Galjaard H, Barranger JA, Reuser AJ, Tager JM. Monoclonal antibodies against human beta-glucocerebrosidase. European Journal of Biochemistry / Febs. 134: 585-9. PMID 6192991  1
1983 Chester MA, Lundblad A, Häger A, Sjöblad S, Loonen C, Tager JM, Zopf D. Increased urinary excretion of a glycogen-derived tetrasaccharide in heterozygotes with glycogen storage diseases type II and III. Lancet. 1: 994-5. PMID 6132305 DOI: 10.1016/S0140-6736(83)92122-0  1
1982 Groen AK, Vervoorn RC, Wanders RJA, Van der Meer R, Tager JM. An evaluation of the metabolite indicator method for determining the cytosolic phosphate potential in rat liver cells Bba - Molecular Cell Research. 721: 172-177. PMID 7138915 DOI: 10.1016/0167-4889(82)90065-9  1
1982 Meuwissen SGM, Dingemans KP, Strijland A, Tager JM, Ooms BC. Ultrastructural and biochemical liver analyses in Fabry's disease Hepatology. 2: 263-268. PMID 6802742  1
1982 Steckel F, Gieselmann V, Waheed A, Hasilik A, von Figura K, Elferink RO, Kalsbeek R, Tager JM. Biosynthesis of acid α-glucosidase in late-onset forms of glycogenosis type II (Pompe's disease) Febs Letters. 150: 69-76. PMID 6761145 DOI: 10.1016/0014-5793(82)81306-9  1
1981 Hollemans M, Elferink RO, De Groot PG, Strijland A, Tager JM. Accumulation of weak bases in relation to intralysosomal pH in cultured human skin fibroblasts. Biochimica Et Biophysica Acta. 643: 140-51. PMID 7236683  0.68
1981 De Groot PG, Ovde Elferink RO, Hollemans M, Strijland A, Westerveld A, Meera Khan P, Tager JM. Inactivation by chloroquine of alpha-galactosidase in cultured human skin fibroblasts. Experimental Cell Research. 136: 327-33. PMID 6273196 DOI: 10.1016/0014-4827(81)90011-2  1
1980 Wanders RJ, Hoek JB, Tager JM. Origin of the ammonia found in protein-free extracts of rat-liver mitochondria and rat hepatocytes. European Journal of Biochemistry. 110: 197-202. PMID 7439158  1
1980 de Groot PG, Strijland A, Kalsbeek R, Meera Khan P, Westerveld A, Hamers MN, Tager JM. Effect of 2-deoxyglucose on lysosomal enzymes in cultured human skin fibroblasts. Experimental Cell Research. 126: 207-16. PMID 6244168 DOI: 10.1016/0014-4827(80)90487-5  1
1978 de Groot PG, Westerveld A, Meera Khan P, Tager JM. Localization of a gene for human alpha-galactosidase B (= n-acetyl-alpha-d-galactosaminidase) on chromosome 22. Human Genetics. 44: 305-12. PMID 215508 DOI: 10.1007/BF00394295  1
1978 Schram AW, De Groot PG, Hamers MN, Brouwer-Kelder B, Donker-Koopman WE, Tager JM. Further characterization of two forms of N-acetyl-alpha-galactosaminidase from human liver. Biochimica Et Biophysica Acta. 525: 410-6. PMID 210819  0.68
1978 de Groot PG, Hamers MN, Westerveld A, Schram AW, Meera Khan P, Tager JM. A new immunochemical method for the quantitative measurement of specific gene products in man-rodent somatic cell hybrids. Human Genetics. 44: 295-304. PMID 83282 DOI: 10.1007/BF00394294  1
1974 Hoek JB, Ernster L, de Haan EJ, Tager JM. The nicotinamide nucleotide specificity of glutamate dehydrogenase in intact rat-liver mitochondria. Biochimica Et Biophysica Acta. 333: 546-59. PMID 4152605 DOI: 10.1016/0005-2728(74)90138-8  1
1973 Hoek JB, Tager JM. The oxidoreduction state of free NAD(P) and mass-action ratio of total nicotinamide nucleotides in isolated ratliver mitochondria Bba - Bioenergetics. 325: 197-212. PMID 4148618 DOI: 10.1016/0005-2728(73)90096-0  1
1972 Meijer AJ, Brouwer A, Reijngoud DJ, Hoek JB, Tager JM. Transport of glutamate in rat-liver mitochondria. Biochimica Et Biophysica Acta. 283: 421-9. PMID 4649357  1
1971 Sluse FE, Meijer AJ, Tager JM. Anion translocators in rat-heart mitochondria. Febs Letters. 18: 149-153. PMID 11946108  1
1971 Lofrumento NE, Hoek JB, Meyer AJ, Tager JM. Phosphate transport in rat-liver mitochondria. Biochimica Et Biophysica Acta. 226: 297-308. PMID 5575160  1
1969 Hoek JB, Charles R, De Haan EJ, Tager JM. Glutamate oxidation in rat-liver homogenate. Biochimica Et Biophysica Acta. 172: 407-16. PMID 5782247  1
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