| Year |
Citation |
Score |
| 2023 |
Di Raddo ME, Milenkovic M, Sivasubramanian M, Hasbi A, Bergman J, Withey S, Madras BK, George SR. Δ9-Tetrahydrocannabinol does not upregulate an aversive dopamine receptor mechanism in adolescent brain unlike in adults. Current Research in Neurobiology. 5: 100107. PMID 38020805 DOI: 10.1016/j.crneur.2023.100107 |
0.321 |
|
| 2022 |
Hasbi A, Madras BK, George SR. Daily Δ-Tetrahydrocannabinol and Withdrawal Increase Dopamine D-D Receptor Heteromer to Mediate Anhedonia- and Anxiogenic-like Behavior Through a Dynorphin and Kappa Opioid Receptor Mechanism. Biological Psychiatry Global Open Science. 3: 550-566. PMID 37519471 DOI: 10.1016/j.bpsgos.2022.07.003 |
0.42 |
|
| 2021 |
Williams OOF, Coppolino M, George SR, Perreault ML. Sex Differences in Dopamine Receptors and Relevance to Neuropsychiatric Disorders. Brain Sciences. 11. PMID 34573220 DOI: 10.3390/brainsci11091199 |
0.34 |
|
| 2020 |
Hasbi A, Sivasubramanian M, Milenkovic M, Komarek K, Madras BK, George SR. Dopamine D1-D2 receptor heteromer expression in key brain regions of rat and higher species: Upregulation in rat striatum after cocaine administration. Neurobiology of Disease. 105017. PMID 32679312 DOI: 10.1016/J.Nbd.2020.105017 |
0.541 |
|
| 2020 |
Hasbi A, Nguyen T, Rahal H, Manduca JD, Miksys S, Tyndale RF, Madras BK, Perreault ML, George SR. Sex difference in dopamine D1-D2 receptor complex expression and signaling affects depression- and anxiety-like behaviors. Biology of Sex Differences. 11: 8. PMID 32087746 DOI: 10.1186/S13293-020-00285-9 |
0.451 |
|
| 2019 |
Hasbi A, Madras BK, Bergman J, Kohut S, Lin Z, Withey SL, George SR. Δ-Tetrahydrocannabinol Increases Dopamine D1-D2 Receptor Heteromer and Elicits Phenotypic Reprogramming in Adult Primate Striatal Neurons. Iscience. 23: 100794. PMID 31972514 DOI: 10.1016/J.Isci.2019.100794 |
0.485 |
|
| 2017 |
Hasbi A, Perreault ML, Shen MYF, Fan T, Nguyen T, Alijaniaram M, Banasikowski TJ, Grace AA, O'Dowd BF, Fletcher PJ, George SR. Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB. Frontiers in Pharmacology. 8: 924. PMID 29354053 DOI: 10.3389/Fphar.2017.00924 |
0.653 |
|
| 2017 |
Perreault ML, Fan T, Banasikowski TJ, Grace AA, George SR. The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction. The European Journal of Neuroscience. PMID 28677227 DOI: 10.1111/Ejn.13635 |
0.406 |
|
| 2016 |
Payer D, Williams B, Mansouri E, Stevanovski S, Nakajima S, Le Foll B, Kish S, Houle S, Mizrahi R, George SR, George TP, Boileau I. Corticotropin-releasing hormone and dopamine release in healthy individuals. Psychoneuroendocrinology. 76: 192-196. PMID 27951520 DOI: 10.1016/J.Psyneuen.2016.11.034 |
0.381 |
|
| 2016 |
Rico AJ, Dopeso-Reyes IG, Martínez-Pinilla E, Sucunza D, Pignataro D, Roda E, Marín-Ramos D, Labandeira-García JL, George SR, Franco R, Lanciego JL. Neurochemical evidence supporting dopamine D1-D2 receptor heteromers in the striatum of the long-tailed macaque: changes following dopaminergic manipulation. Brain Structure & Function. PMID 27612857 DOI: 10.1007/S00429-016-1306-X |
0.533 |
|
| 2016 |
Perreault ML, Hasbi A, Shen MY, Fan T, Navarro G, Fletcher PJ, Franco R, Lanciego JL, George SR. Disruption of a dopamine receptor complex amplifies the actions of cocaine. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27480020 DOI: 10.1016/J.Euroneuro.2016.07.008 |
0.499 |
|
| 2015 |
Shen MY, Perreault ML, Bambico FR, Jones-Tabah J, Cheung M, Fan T, Nobrega JN, George SR. Rapid anti-depressant and anxiolytic actions following dopamine D1-D2 receptor heteromer inactivation. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26431907 DOI: 10.1016/J.Euroneuro.2015.09.004 |
0.429 |
|
| 2015 |
Huroy S, Kanawaty A, Magomedova L, Cummins CL, George SR, van der Kooy D, Henderson JT. EphB2 Reverse Signaling Regulates Learned Opiate Tolerance via Hippocampal Function. Behavioural Brain Research. PMID 26408450 DOI: 10.1016/J.Bbr.2015.09.023 |
0.373 |
|
| 2015 |
Perreault ML, Shen MY, Fan T, George SR. Regulation of c-fos expression by the dopamine D1-D2 receptor heteromer. Neuroscience. 285: 194-203. PMID 25446350 DOI: 10.1016/J.Neuroscience.2014.11.017 |
0.503 |
|
| 2015 |
Shen MY, Perreault ML, Fan T, George SR. The dopamine D1-D2 receptor heteromer exerts a tonic inhibitory effect on the expression of amphetamine-induced locomotor sensitization. Pharmacology, Biochemistry, and Behavior. 128: 33-40. PMID 25444866 DOI: 10.1016/J.Pbb.2014.11.011 |
0.514 |
|
| 2014 |
Hasbi A, Perreault ML, Shen MY, Zhang L, To R, Fan T, Nguyen T, Ji X, O'Dowd BF, George SR. A peptide targeting an interaction interface disrupts the dopamine D1-D2 receptor heteromer to block signaling and function in vitro and in vivo: effective selective antagonism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4806-20. PMID 25063849 DOI: 10.1096/Fj.14-254037 |
0.738 |
|
| 2014 |
Kabli N, Fan T, O'Dowd BF, George SR. μ-δ opioid receptor heteromer-specific signaling in the striatum and hippocampus. Biochemical and Biophysical Research Communications. 450: 906-11. PMID 24976397 DOI: 10.1016/J.Bbrc.2014.06.099 |
0.822 |
|
| 2014 |
George SR, Kern A, Smith RG, Franco R. Dopamine receptor heteromeric complexes and their emerging functions. Progress in Brain Research. 211: 183-200. PMID 24968781 DOI: 10.1016/B978-0-444-63425-2.00008-8 |
0.549 |
|
| 2014 |
Perreault ML, O'Dowd BF, George SR. Dopamine Dâ‚-Dâ‚‚ receptor heteromer regulates signaling cascades involved in addiction: potential relevance to adolescent drug susceptibility. Developmental Neuroscience. 36: 287-96. PMID 24820626 DOI: 10.1159/000360158 |
0.678 |
|
| 2014 |
Finnema SJ, Stepanov V, Nakao R, Sromek AW, Zhang T, Neumeyer JL, George SR, Seeman P, Stabin MG, Jonsson C, Farde L, Halldin C. (18)F-MCL-524, an (18)F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1164-70. PMID 24790219 DOI: 10.2967/Jnumed.113.133876 |
0.494 |
|
| 2014 |
Kabli N, Nguyen T, Balboni G, O'Dowd BF, George SR. Antidepressant-like and anxiolytic-like effects following activation of the μ-δ opioid receptor heteromer in the nucleus accumbens. Molecular Psychiatry. 19: 986-94. PMID 24061495 DOI: 10.1038/Mp.2013.115 |
0.772 |
|
| 2014 |
Perreault ML, Hasbi A, O'Dowd BF, George SR. Heteromeric dopamine receptor signaling complexes: emerging neurobiology and disease relevance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 156-68. PMID 23774533 DOI: 10.1038/Npp.2013.148 |
0.711 |
|
| 2014 |
Perreault ML, O'Dowd BF, George SR. Dopamine D1-D2 Receptor Heteromer regulates signaling cascades involved in addiction: Potential relevance to adolescent drug susceptibility Developmental Neuroscience. 36: 287-296. DOI: 10.1159/0003601586 |
0.42 |
|
| 2013 |
Perreault ML, Fan T, O'Dowd BF, George SR. Enhanced brain-derived neurotrophic factor signaling in the nucleus accumbens of juvenile rats. Developmental Neuroscience. 35: 384-95. PMID 24021607 DOI: 10.1159/000351026 |
0.689 |
|
| 2013 |
Ting-A-Kee R, Mercuriano LE, Vargas-Perez H, George SR, van der Kooy D. Dopamine D1 receptors are not critical for opiate reward but can mediate opiate memory retrieval in a state-dependent manner. Behavioural Brain Research. 247: 174-7. PMID 23538064 DOI: 10.1016/J.Bbr.2013.03.026 |
0.543 |
|
| 2013 |
O'Dowd BF, Nguyen T, Ji X, George SR. D5 dopamine receptor carboxyl tail involved in D5-D2 heteromer formation. Biochemical and Biophysical Research Communications. 431: 586-9. PMID 23318175 DOI: 10.1016/J.Bbrc.2012.12.139 |
0.746 |
|
| 2013 |
Novak G, Fan T, O'Dowd BF, George SR. Postnatal maternal deprivation and pubertal stress have additive effects on dopamine D2 receptor and CaMKII beta expression in the striatum. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 31: 189-95. PMID 23313435 DOI: 10.1016/J.Ijdevneu.2013.01.001 |
0.639 |
|
| 2013 |
Novak G, Fan T, O'Dowd BF, George SR. Striatal development involves a switch in gene expression networks, followed by a myelination event: implications for neuropsychiatric disease. Synapse (New York, N.Y.). 67: 179-88. PMID 23184870 DOI: 10.1002/Syn.21628 |
0.628 |
|
| 2013 |
Perreault ML, Jones-Tabah J, O'Dowd BF, George SR. A physiological role for the dopamine D5 receptor as a regulator of BDNF and Akt signalling in rodent prefrontal cortex. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 477-83. PMID 22827965 DOI: 10.1017/S1461145712000685 |
0.725 |
|
| 2013 |
Novak G, Fan T, O'Dowd BF, George SR. Striatal neurodevelopment involves a switch in gene expression and a myelination event F1000research. 4. DOI: 10.7490/F1000Research.1092847.1 |
0.564 |
|
| 2012 |
Perreault ML, Hasbi A, Alijaniaram M, O'Dowd BF, George SR. Reduced striatal dopamine D1-D2 receptor heteromer expression and behavioural subsensitivity in juvenile rats. Neuroscience. 225: 130-9. PMID 22986162 DOI: 10.1016/J.Neuroscience.2012.08.042 |
0.547 |
|
| 2012 |
O'Dowd BF, Ji X, O'Dowd PB, Nguyen T, George SR. Disruption of the mu-delta opioid receptor heteromer. Biochemical and Biophysical Research Communications. 422: 556-60. PMID 22583900 DOI: 10.1016/J.Bbrc.2012.05.023 |
0.689 |
|
| 2012 |
Perreault ML, Fan T, Alijaniaram M, O'Dowd BF, George SR. Dopamine D1-D2 receptor heteromer in dual phenotype GABA/glutamate-coexpressing striatal medium spiny neurons: regulation of BDNF, GAD67 and VGLUT1/2. Plos One. 7: e33348. PMID 22428025 DOI: 10.1371/Journal.Pone.0033348 |
0.706 |
|
| 2012 |
Grieder TE, George O, Tan H, George SR, Le Foll B, Laviolette SR, van der Kooy D. Phasic D1 and tonic D2 dopamine receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 109: 3101-6. PMID 22308372 DOI: 10.1073/Pnas.1114422109 |
0.421 |
|
| 2012 |
O'Dowd BF, Ji X, Nguyen T, George SR. Two amino acids in each of D1 and D2 dopamine receptor cytoplasmic regions are involved in D1-D2 heteromer formation. Biochemical and Biophysical Research Communications. 417: 23-8. PMID 22100647 DOI: 10.1016/J.Bbrc.2011.11.027 |
0.732 |
|
| 2011 |
Perreault ML, Hasbi A, O'Dowd BF, George SR. The dopamine d1-d2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in Basal Ganglia. Frontiers in Neuroanatomy. 5: 31. PMID 21747759 DOI: 10.3389/Fnana.2011.00031 |
0.734 |
|
| 2011 |
Sromek AW, Si YG, Zhang T, George SR, Seeman P, Neumeyer JL. Synthesis and Biological Evaluation of N-Fluoroalkyl and 2-Fluoroalkoxy Substituted Aporphines: Potential PET Ligands for Dopamine D(2) Receptors. Acs Medicinal Chemistry Letters. 2: 189-194. PMID 21666830 DOI: 10.1021/Ml1001689 |
0.467 |
|
| 2011 |
Hasbi A, O'Dowd BF, George SR. Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance. Molecular Brain. 4: 26. PMID 21663703 DOI: 10.1186/1756-6606-4-26 |
0.76 |
|
| 2011 |
O'Dowd BF, Ji X, Alijaniaram M, Nguyen T, George SR. Separation and reformation of cell surface dopamine receptor oligomers visualized in cells. European Journal of Pharmacology. 658: 74-83. PMID 21371461 DOI: 10.1016/J.Ejphar.2011.02.030 |
0.77 |
|
| 2011 |
Kong MM, Verma V, O'Dowd BF, George SR. The role of palmitoylation in directing dopamine D1 receptor internalization through selective endocytic routes. Biochemical and Biophysical Research Communications. 405: 445-9. PMID 21241663 DOI: 10.1016/J.Bbrc.2011.01.050 |
0.813 |
|
| 2011 |
Perreault ML, O'Dowd BF, George SR. Dopamine receptor homooligomers and heterooligomers in schizophrenia. Cns Neuroscience & Therapeutics. 17: 52-7. PMID 21199449 DOI: 10.1111/J.1755-5949.2010.00228.X |
0.743 |
|
| 2011 |
Perreault ML, Hasbi A, Alijaniaram M, O’Dowd BF, George SR. Dopamine D1 and D2 receptor coexpression in medium spiny neurons: Potential role for the dopamine D1-D2 receptor heteromer in schizophrenia F1000research. 2. DOI: 10.7490/F1000Research.1646.1 |
0.55 |
|
| 2010 |
Kabli N, Martin N, Fan T, Nguyen T, Hasbi A, Balboni G, O'Dowd BF, George SR. Agonists at the δ-opioid receptor modify the binding of µ-receptor agonists to the µ-δ receptor hetero-oligomer. British Journal of Pharmacology. 161: 1122-36. PMID 20977461 DOI: 10.1111/J.1476-5381.2010.00944.X |
0.834 |
|
| 2010 |
Perreault ML, Hasbi A, Alijaniaram M, Fan T, Varghese G, Fletcher PJ, Seeman P, O'Dowd BF, George SR. The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia. The Journal of Biological Chemistry. 285: 36625-34. PMID 20864528 DOI: 10.1074/Jbc.M110.159954 |
0.733 |
|
| 2010 |
Verma V, Hasbi A, O'Dowd BF, George SR. Dopamine D1-D2 receptor Heteromer-mediated calcium release is desensitized by D1 receptor occupancy with or without signal activation: dual functional regulation by G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 285: 35092-103. PMID 20807772 DOI: 10.1074/Jbc.M109.088625 |
0.811 |
|
| 2010 |
Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, et al. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics (Oxford, England). 26: 1804-5. PMID 20501551 DOI: 10.1093/Bioinformatics/Btq264 |
0.4 |
|
| 2010 |
Lee DK, Ferguson SS, George SR, O'Dowd BF. The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin. Biochemical and Biophysical Research Communications. 395: 185-9. PMID 20353754 DOI: 10.1016/J.Bbrc.2010.03.151 |
0.682 |
|
| 2010 |
Hasbi A, O'Dowd BF, George SR. Heteromerization of dopamine D2 receptors with dopamine D1 or D5 receptors generates intracellular calcium signaling by different mechanisms. Current Opinion in Pharmacology. 10: 93-9. PMID 19897420 DOI: 10.1016/J.Coph.2009.09.011 |
0.719 |
|
| 2010 |
Ng J, Rashid AJ, So CH, O'Dowd BF, George SR. Activation of calcium/calmodulin-dependent protein kinase IIalpha in the striatum by the heteromeric D1-D2 dopamine receptor complex. Neuroscience. 165: 535-41. PMID 19837142 DOI: 10.1016/J.Neuroscience.2009.10.017 |
0.557 |
|
| 2010 |
El-Ghundi MB, Fan T, Karasinska JM, Yeung J, Zhou M, O'Dowd BF, George SR. Restoration of amphetamine-induced locomotor sensitization in dopamine D1 receptor-deficient mice. Psychopharmacology. 207: 599-618. PMID 19830406 DOI: 10.1007/S00213-009-1690-5 |
0.844 |
|
| 2010 |
Hasbi A, O’Dowd BF, George SR. Signaling of dopamine receptor homo- and heterooligomers G Protein-Coupled Receptors: Structure, Signaling, and Physiology. 90-110. DOI: 10.1017/CBO9780511760334.006 |
0.461 |
|
| 2009 |
Hasbi A, Fan T, Alijaniaram M, Nguyen T, Perreault ML, O'Dowd BF, George SR. Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth. Proceedings of the National Academy of Sciences of the United States of America. 106: 21377-82. PMID 19948956 DOI: 10.1073/Pnas.0903676106 |
0.669 |
|
| 2009 |
Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131 |
0.403 |
|
| 2009 |
So CH, Verma V, Alijaniaram M, Cheng R, Rashid AJ, O'Dowd BF, George SR. Calcium signaling by dopamine D5 receptor and D5-D2 receptor hetero-oligomers occurs by a mechanism distinct from that for dopamine D1-D2 receptor hetero-oligomers. Molecular Pharmacology. 75: 843-54. PMID 19171671 DOI: 10.1124/Mol.108.051805 |
0.791 |
|
| 2008 |
Natesan S, Reckless GE, Barlow KBL, Odontiadis J, Nobrega JN, Baker GB, George SR, Mamo D, Kapur S. The antipsychotic potential of l-stepholidine - A naturally occurring dopamine receptor D1 agonist and D2 antagonist Psychopharmacology. 199: 275-289. PMID 18521575 DOI: 10.1007/S00213-008-1172-1 |
0.507 |
|
| 2008 |
Juhasz JR, Hasbi A, Rashid AJ, So CH, George SR, O'Dowd BF. Mu-opioid receptor heterooligomer formation with the dopamine D1 receptor as directly visualized in living cells. European Journal of Pharmacology. 581: 235-43. PMID 18237729 DOI: 10.1016/J.Ejphar.2007.11.060 |
0.758 |
|
| 2007 |
George SR, O'Dowd BF. A novel dopamine receptor signaling unit in brain: heterooligomers of D1 and D2 dopamine receptors. Thescientificworldjournal. 7: 58-63. PMID 17982577 DOI: 10.1100/tsw.2007.223 |
0.737 |
|
| 2007 |
Rashid AJ, O'Dowd BF, Verma V, George SR. Neuronal Gq/11-coupled dopamine receptors: an uncharted role for dopamine. Trends in Pharmacological Sciences. 28: 551-5. PMID 17950471 DOI: 10.1016/J.Tips.2007.10.001 |
0.742 |
|
| 2007 |
Hasbi A, Nguyen T, Fan T, Cheng R, Rashid A, Alijaniaram M, Rasenick MM, O'Dowd BF, George SR. Trafficking of preassembled opioid mu-delta heterooligomer-Gz signaling complexes to the plasma membrane: coregulation by agonists. Biochemistry. 46: 12997-3009. PMID 17941650 DOI: 10.1021/Bi701436W |
0.687 |
|
| 2007 |
Kong MM, Hasbi A, Mattocks M, Fan T, O'Dowd BF, George SR. Regulation of D1 dopamine receptor trafficking and signaling by caveolin-1. Molecular Pharmacology. 72: 1157-70. PMID 17699686 DOI: 10.1124/mol.107.034769 |
0.683 |
|
| 2007 |
Skrabanek L, Murcia M, Bouvier M, Devi L, George SR, Lohse MJ, Milligan G, Neubig R, Palczewski K, Parmentier M, Pin JP, Vriend G, Javitch JA, Campagne F, Filizola M. Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. Bmc Bioinformatics. 8: 177. PMID 17537266 DOI: 10.1186/1471-2105-8-177 |
0.366 |
|
| 2007 |
So CH, Verma V, O'Dowd BF, George SR. Desensitization of the dopamine D1 and D2 receptor hetero-oligomer mediated calcium signal by agonist occupancy of either receptor. Molecular Pharmacology. 72: 450-62. PMID 17519357 DOI: 10.1124/Mol.107.034884 |
0.784 |
|
| 2007 |
El-Ghundi M, O'Dowd BF, George SR. Insights into the role of dopamine receptor systems in learning and memory. Reviews in the Neurosciences. 18: 37-66. PMID 17405450 DOI: 10.1515/Revneuro.2007.18.1.37 |
0.831 |
|
| 2007 |
O'Dowd BF, Alijaniaram M, Ji X, Nguyen T, Eglen RM, George SR. Using ligand-induced conformational change to screen for compounds targeting G-protein-coupled receptors. Journal of Biomolecular Screening. 12: 175-85. PMID 17289935 DOI: 10.1177/1087057106298287 |
0.629 |
|
| 2007 |
Rashid AJ, So CH, Kong MM, Furtak T, El-Ghundi M, Cheng R, O'Dowd BF, George SR. D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 104: 654-9. PMID 17194762 DOI: 10.1073/Pnas.0604049104 |
0.856 |
|
| 2006 |
Kong MM, Fan T, Varghese G, O'dowd BF, George SR. Agonist-induced cell surface trafficking of an intracellularly sequestered D1 dopamine receptor homo-oligomer. Molecular Pharmacology. 70: 78-89. PMID 16597839 DOI: 10.1124/mol.105.021246 |
0.707 |
|
| 2006 |
Lee DK, George SR, O'Dowd BF. Unravelling the roles of the apelin system: prospective therapeutic applications in heart failure and obesity. Trends in Pharmacological Sciences. 27: 190-4. PMID 16530855 DOI: 10.1016/j.tips.2006.02.006 |
0.632 |
|
| 2006 |
Rashid A, So C, O'Dowd B, George S. S.19.05 Heterooligomerization of D1 and D2 dopamine receptors in brain: implications for psychosis? European Neuropsychopharmacology. 16: S193. DOI: 10.1016/S0924-977X(06)70097-9 |
0.549 |
|
| 2005 |
Karasinska JM, George SR, Cheng R, O'Dowd BF. Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine-induced locomotor activity, reward and CREB phosphorylation. The European Journal of Neuroscience. 22: 1741-50. PMID 16197514 DOI: 10.1111/j.1460-9568.2005.04353.x |
0.662 |
|
| 2005 |
Fan T, Varghese G, Nguyen T, Tse R, O'Dowd BF, George SR. A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers. The Journal of Biological Chemistry. 280: 38478-88. PMID 16159882 DOI: 10.1074/Jbc.M505644200 |
0.728 |
|
| 2005 |
O'Dowd BF, Ji X, Alijaniaram M, Rajaram RD, Kong MM, Rashid A, Nguyen T, George SR. Dopamine receptor oligomerization visualized in living cells. The Journal of Biological Chemistry. 280: 37225-35. PMID 16115864 DOI: 10.1074/Jbc.M504562200 |
0.744 |
|
| 2005 |
Hasbi A, O'Dowd BF, George SR. A G protein-coupled receptor for estrogen: the end of the search? Molecular Interventions. 5: 158-61. PMID 15994455 DOI: 10.1124/mi.5.3.5 |
0.606 |
|
| 2005 |
So CH, Varghese G, Curley KJ, Kong MM, Alijaniaram M, Ji X, Nguyen T, O'dowd BF, George SR. D1 and D2 dopamine receptors form heterooligomers and cointernalize after selective activation of either receptor. Molecular Pharmacology. 68: 568-78. PMID 15923381 DOI: 10.1124/Mol.105.012229 |
0.726 |
|
| 2005 |
Seeman P, Weinshenker D, Quirion R, Srivastava LK, Bhardwaj SK, Grandy DK, Premont RT, Sotnikova TD, Boksa P, El-Ghundi M, O'dowd BF, George SR, Perreault ML, Männistö PT, Robinson S, et al. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 3513-8. PMID 15716360 DOI: 10.1073/Pnas.0409766102 |
0.82 |
|
| 2005 |
Lee DK, Saldivia VR, Nguyen T, Cheng R, George SR, O'Dowd BF. Modification of the terminal residue of apelin-13 antagonizes its hypotensive action. Endocrinology. 146: 231-6. PMID 15486224 DOI: 10.1210/En.2004-0359 |
0.581 |
|
| 2004 |
Lee SP, So CH, Rashid AJ, Varghese G, Cheng R, Lança AJ, O'Dowd BF, George SR. Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. The Journal of Biological Chemistry. 279: 35671-8. PMID 15159403 DOI: 10.1074/Jbc.M401923200 |
0.748 |
|
| 2004 |
Rashid AJ, O'Dowd BF, George SR. Minireview: Diversity and complexity of signaling through peptidergic G protein-coupled receptors. Endocrinology. 145: 2645-52. PMID 15044354 DOI: 10.1210/En.2004-0052 |
0.658 |
|
| 2004 |
Lee DK, Lança AJ, Cheng R, Nguyen T, Ji XD, Gobeil F, Chemtob S, George SR, O'Dowd BF. Agonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptors. The Journal of Biological Chemistry. 279: 7901-8. PMID 14645236 DOI: 10.1074/Jbc.M306377200 |
0.701 |
|
| 2003 |
Madras BK, Fahey MA, Miller GM, De La Garza R, Goulet M, Spealman RD, Meltzer PC, George SR, O'Dowd BF, Bonab AA, Livni E, Fischman AJ. Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors. European Journal of Pharmacology. 479: 41-51. PMID 14612136 DOI: 10.1016/J.Ejphar.2003.08.055 |
0.581 |
|
| 2003 |
Lee DK, George SR, O'Dowd BF. Continued discovery of ligands for G protein-coupled receptors. Life Sciences. 74: 293-7. PMID 14607257 DOI: 10.1016/J.Lfs.2003.09.016 |
0.713 |
|
| 2003 |
Lee SP, O'Dowd BF, George SR. Homo- and hetero-oligomerization of G protein-coupled receptors. Life Sciences. 74: 173-80. PMID 14607244 DOI: 10.1016/J.Lfs.2003.09.028 |
0.743 |
|
| 2003 |
Vanti WB, Muglia P, Nguyen T, Cheng R, Kennedy JL, George SR, O'Dowd BF. Discovery of a null mutation in a human trace amine receptor gene. Genomics. 82: 531-6. PMID 14559210 DOI: 10.1016/S0888-7543(03)00173-3 |
0.679 |
|
| 2003 |
Thompson MD, Storm van's Gravesande K, Galczenski H, Burnham WM, Siminovitch KA, Zamel N, Slutsky A, Drazen JM, George SR, Evans JF, O'Dowd BF. A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha. Pharmacogenetics. 13: 641-9. PMID 14515063 DOI: 10.1097/01.fpc.0000054127.14659.42 |
0.652 |
|
| 2003 |
Lee SP, O'Dowd BF, Rajaram RD, Nguyen T, George SR. D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4. Biochemistry. 42: 11023-31. PMID 12974638 DOI: 10.1021/Bi0345539 |
0.731 |
|
| 2003 |
George SR, Ng GY, Lee SP, Fan T, Varghese G, Wang C, Deber CM, Seeman P, O'Dowd BF. Blockade of G protein-coupled receptors and the dopamine transporter by a transmembrane domain peptide: novel strategy for functional inhibition of membrane proteins in vivo. The Journal of Pharmacology and Experimental Therapeutics. 307: 481-9. PMID 12970389 DOI: 10.1124/Jpet.103.053843 |
0.699 |
|
| 2003 |
Vanti WB, Nguyen T, Cheng R, Lynch KR, George SR, O'Dowd BF. Novel human G-protein-coupled receptors. Biochemical and Biophysical Research Communications. 305: 67-71. PMID 12732197 DOI: 10.1016/S0006-291X(03)00709-5 |
0.635 |
|
| 2003 |
Karasinska JM, George SR, O'Dowd BF. Family 1 G protein-coupled receptor function in the CNS. Insights from gene knockout mice. Brain Research. Brain Research Reviews. 41: 125-52. PMID 12663079 DOI: 10.1016/S0165-0173(02)00221-7 |
0.675 |
|
| 2003 |
El-Ghundi M, O'Dowd BF, Erclik M, George SR. Attenuation of sucrose reinforcement in dopamine D1 receptor deficient mice. The European Journal of Neuroscience. 17: 851-62. PMID 12603275 DOI: 10.1046/J.1460-9568.2003.02496.X |
0.818 |
|
| 2002 |
George SR, O'Dowd BF, Lee SP. G-protein-coupled receptor oligomerization and its potential for drug discovery. Nature Reviews. Drug Discovery. 1: 808-20. PMID 12360258 DOI: 10.1038/Nrd913 |
0.658 |
|
| 2002 |
Lee DK, George SR, O'Dowd BF. Novel G-protein-coupled receptor genes expressed in the brain: continued discovery of important therapeutic targets. Expert Opinion On Therapeutic Targets. 6: 185-202. PMID 12223080 DOI: 10.1517/14728222.6.2.185 |
0.691 |
|
| 2002 |
Levac BA, O'Dowd BF, George SR. Oligomerization of opioid receptors: generation of novel signaling units. Current Opinion in Pharmacology. 2: 76-81. PMID 11786312 DOI: 10.1016/S1471-4892(02)00124-8 |
0.706 |
|
| 2002 |
Lamey M, Thompson M, Varghese G, Chi H, Sawzdargo M, George SR, O'Dowd BF. Distinct residues in the carboxyl tail mediate agonist-induced desensitization and internalization of the human dopamine D1 receptor. The Journal of Biological Chemistry. 277: 9415-21. PMID 11773080 DOI: 10.1074/Jbc.M111811200 |
0.739 |
|
| 2001 |
Lee DK, George SR, Evans JF, Lynch KR, O'Dowd BF. Orphan G protein-coupled receptors in the CNS. Current Opinion in Pharmacology. 1: 31-9. PMID 11712532 DOI: 10.1016/S1471-4892(01)00003-0 |
0.448 |
|
| 2001 |
Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF. Discovery and mapping of ten novel G protein-coupled receptor genes. Gene. 275: 83-91. PMID 11574155 DOI: 10.1016/S0378-1119(01)00651-5 |
0.66 |
|
| 2001 |
Clements MK, McDonald TP, Wang R, Xie G, O'Dowd BF, George SR, Austin CP, Liu Q. FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54. Biochemical and Biophysical Research Communications. 284: 1189-93. PMID 11414709 DOI: 10.1006/Bbrc.2001.5098 |
0.663 |
|
| 2001 |
Nguyen T, Shapiro DA, George SR, Setola V, Lee DK, Cheng R, Rauser L, Lee SP, Lynch KR, Roth BL, O'Dowd BF. Discovery of a novel member of the histamine receptor family. Molecular Pharmacology. 59: 427-33. PMID 11179435 DOI: 10.1124/Mol.59.3.427 |
0.677 |
|
| 2001 |
El-Ghundi M, O'Dowd BF, George SR. Prolonged fear responses in mice lacking dopamine D1 receptor. Brain Research. 892: 86-93. PMID 11172752 DOI: 10.1016/S0006-8993(00)03234-0 |
0.806 |
|
| 2001 |
Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF. Identification of four novel human G protein-coupled receptors expressed in the brain. Brain Research. Molecular Brain Research. 86: 13-22. PMID 11165367 DOI: 10.1016/S0169-328X(00)00242-4 |
0.445 |
|
| 2001 |
Bailey WJ, Vanti WB, George SR, Blevins R, Swaminathan S, Bonini JA, Smith KE, Weinshank RL, O'Dowd BF. Patent status of the therapeutically important G-protein-coupled receptors Expert Opinion On Therapeutic Patents. 11: 1861-1887. DOI: 10.1517/13543776.11.12.1861 |
0.429 |
|
| 2001 |
Levac BAR, Dowd BF, George SR. Opioids: Molecular basis of action Current Opinion in Endocrinology and Diabetes. 8: 166-171. DOI: 10.1097/00060793-200106000-00010 |
0.346 |
|
| 2000 |
Thompson MD, Gonzalez N, Nguyen T, Comings DE, George SR, O'Dowd BF. Serotonin transporter gene polymorphisms in alcohol dependence. Alcohol (Fayetteville, N.Y.). 22: 61-7. PMID 11113619 DOI: 10.1016/S0741-8329(00)00105-1 |
0.535 |
|
| 2000 |
Elmhurst JL, Xie Z, O'Dowd BF, George SR. The splice variant D3nf reduces ligand binding to the D3 dopamine receptor: evidence for heterooligomerization. Brain Research. Molecular Brain Research. 80: 63-74. PMID 11039730 DOI: 10.1016/S0169-328X(00)00120-0 |
0.61 |
|
| 2000 |
Lee SP, Xie Z, Varghese G, Nguyen T, O'Dowd BF, George SR. Oligomerization of dopamine and serotonin receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: S32-40. PMID 11008065 DOI: 10.1016/S0893-133X(00)00155-X |
0.729 |
|
| 2000 |
Vandenbergh DJ, Thompson MD, Cook EH, Bendahhou E, Nguyen T, Krasowski MD, Zarrabian D, Comings D, Sellers EM, Tyndale RF, George SR, O'Dowd BF, Uhl GR. Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations. Molecular Psychiatry. 5: 283-92. PMID 10889531 DOI: 10.1038/Sj.Mp.4000701 |
0.601 |
|
| 2000 |
Karasinska JM, George SR, El-Ghundi M, Fletcher PJ, O'Dowd BF. Modification of dopamine D(1) receptor knockout phenotype in mice lacking both dopamine D(1) and D(3) receptors. European Journal of Pharmacology. 399: 171-81. PMID 10884517 DOI: 10.1016/S0014-2999(00)00347-2 |
0.85 |
|
| 2000 |
Lee SP, O'Dowd BF, Ng GY, Varghese G, Akil H, Mansour A, Nguyen T, George SR. Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell. Molecular Pharmacology. 58: 120-8. PMID 10860933 DOI: 10.1124/Mol.58.1.120 |
0.726 |
|
| 2000 |
Heise CE, O'Dowd BF, Figueroa DJ, Sawyer N, Nguyen T, Im DS, Stocco R, Bellefeuille JN, Abramovitz M, Cheng R, Williams DL, Zeng Z, Liu Q, Ma L, Clements MK, ... ... George SR, et al. Characterization of the human cysteinyl leukotriene 2 receptor. The Journal of Biological Chemistry. 275: 30531-6. PMID 10851239 DOI: 10.1074/Jbc.M003490200 |
0.448 |
|
| 2000 |
George SR, Fan T, Xie Z, Tse R, Tam V, Varghese G, O'Dowd BF. Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties. The Journal of Biological Chemistry. 275: 26128-35. PMID 10842167 DOI: 10.1074/Jbc.M000345200 |
0.719 |
|
| 2000 |
Liu IS, George SR, Seeman P. The human dopamine D2(Longer) receptor has a high-affinity state and inhibits adenylyl cyclase. Brain Research. Molecular Brain Research. 77: 281-4. PMID 10837924 DOI: 10.1016/S0169-328X(00)00064-4 |
0.57 |
|
| 2000 |
Deng HB, Yu Y, Pak Y, O'Dowd BF, George SR, Surratt CK, Uhl GR, Wang JB. Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitization. Biochemistry. 39: 5492-9. PMID 10820022 DOI: 10.1021/Bi991938B |
0.699 |
|
| 2000 |
Tong Y, Chabot JG, Shen SH, O'Dowd BF, George SR, Quirion R. Ontogenic profile of the expression of the mu opioid receptor gene in the rat telencephalon and diencephalon: an in situ hybridization study. Journal of Chemical Neuroanatomy. 18: 209-22. PMID 10781737 DOI: 10.1016/S0891-0618(00)00043-0 |
0.456 |
|
| 2000 |
Im DS, Heise CE, Harding MA, George SR, O'Dowd BF, Theodorescu D, Lynch KR. Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate. Molecular Pharmacology. 57: 753-9. PMID 10727522 DOI: 10.1124/Mol.57.4.753 |
0.652 |
|
| 2000 |
Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, Liu Y, Liu IS, Heng HH, Seeman P, George SR, O'Dowd BF, Marchese A. Cloning and characterization of additional members of the G protein-coupled receptor family. Biochimica Et Biophysica Acta. 1490: 311-23. PMID 10684976 DOI: 10.1016/S0167-4781(99)00241-9 |
0.463 |
|
| 2000 |
O'Dowd BF, Lee DK, Huang W, Nguyen T, Cheng R, Liu Y, Wang B, Gershengorn MC, George SR. TRH-R2 exhibits similar binding and acute signaling but distinct regulation and anatomic distribution compared with TRH-R1. Molecular Endocrinology (Baltimore, Md.). 14: 183-93. PMID 10628757 DOI: 10.1210/Mend.14.1.0407 |
0.311 |
|
| 2000 |
Lee DK, Cheng R, Nguyen T, Fan T, Kariyawasam AP, Liu Y, Osmond DH, George SR, O'Dowd BF. Characterization of apelin, the ligand for the APJ receptor. Journal of Neurochemistry. 74: 34-41. PMID 10617103 DOI: 10.1046/J.1471-4159.2000.0740034.X |
0.624 |
|
| 1999 |
Jin H, Xie Z, George SR, O'Dowd BF. Palmitoylation occurs at cysteine 347 and cysteine 351 of the dopamine D(1) receptor. European Journal of Pharmacology. 386: 305-12. PMID 10618483 DOI: 10.1016/S0014-2999(99)00727-X |
0.697 |
|
| 1999 |
El-Ghundi M, Fletcher PJ, Drago J, Sibley DR, O'Dowd BF, George SR. Spatial learning deficit in dopamine D(1) receptor knockout mice. European Journal of Pharmacology. 383: 95-106. PMID 10585522 DOI: 10.1016/S0014-2999(99)00573-7 |
0.822 |
|
| 1999 |
Liu Q, Pong SS, Zeng Z, Zhang Q, Howard AD, Williams DL, Davidoff M, Wang R, Austin CP, McDonald TP, Bai C, George SR, Evans JF, Caskey CT. Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochemical and Biophysical Research Communications. 266: 174-8. PMID 10581185 DOI: 10.1006/Bbrc.1999.1796 |
0.477 |
|
| 1999 |
Pak Y, O'Dowd BF, Wang JB, George SR. Agonist-induced, G protein-dependent and -independent down-regulation of the mu opioid receptor. The receptor is a direct substrate for protein-tyrosine kinase. The Journal of Biological Chemistry. 274: 27610-6. PMID 10488100 DOI: 10.1074/Jbc.274.39.27610 |
0.489 |
|
| 1999 |
Marchese A, George SR, Kolakowski LF, Lynch KR, O'Dowd BF. Novel GPCRs and their endogenous ligands: expanding the boundaries of physiology and pharmacology. Trends in Pharmacological Sciences. 20: 370-5. PMID 10462760 DOI: 10.1016/S0165-6147(99)01366-8 |
0.483 |
|
| 1999 |
Xie Z, Lee SP, O'Dowd BF, George SR. Serotonin 5-HT(1B) and 5-HT(1D) receptors form homodimers when expressed alone and heterodimers when co-expressed Febs Letters. 456: 63-67. PMID 10452531 DOI: 10.1016/S0014-5793(99)00918-7 |
0.692 |
|
| 1999 |
Lee DK, Nguyen T, Porter CA, Cheng R, George SR, O'Dowd BF. Two related G protein-coupled receptors: the distribution of GPR7 in rat brain and the absence of GPR8 in rodents. Brain Research. Molecular Brain Research. 71: 96-103. PMID 10407191 DOI: 10.1016/S0169-328X(99)00171-0 |
0.656 |
|
| 1999 |
Lee DK, Nguyen T, O'Neill GP, Cheng R, Liu Y, Howard AD, Coulombe N, Tan CP, Tang-Nguyen AT, George SR, O'Dowd BF. Discovery of a receptor related to the galanin receptors. Febs Letters. 446: 103-7. PMID 10100623 DOI: 10.1016/S0014-5793(99)00009-5 |
0.686 |
|
| 1999 |
Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF. Discovery of three novel orphan G-protein-coupled receptors. Genomics. 56: 12-21. PMID 10036181 DOI: 10.1006/Geno.1998.5655 |
0.685 |
|
| 1999 |
Sawzdargo M, Nguyen T, Lee DK, Lynch KR, Cheng R, Heng HH, George SR, O'Dowd BF. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain. Brain Research. Molecular Brain Research. 64: 193-8. PMID 9931487 DOI: 10.1016/S0169-328X(98)00277-0 |
0.672 |
|
| 1999 |
O'Dowd BF, Marchese A, Lee D, Nguyen T, George SR. Novel orphan g protein-coupled receptors Proceedings of the Western Pharmacology Society. 42: 135. |
0.334 |
|
| 1998 |
Zawarynski P, Tallerico T, Seeman P, Lee SP, O'Dowd BF, George SR. Dopamine D2 receptor dimers in human and rat brain Febs Letters. 441: 383-386. PMID 9891976 DOI: 10.1016/S0014-5793(98)01588-9 |
0.742 |
|
| 1998 |
Kolakowski LF, O'Neill GP, Howard AD, Broussard SR, Sullivan KA, Feighner SD, Sawzdargo M, Nguyen T, Kargman S, Shiao LL, Hreniuk DL, Tan CP, Evans J, Abramovitz M, Chateauneuf A, ... ... George SR, et al. Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3. Journal of Neurochemistry. 71: 2239-51. PMID 9832121 DOI: 10.1046/J.1471-4159.1998.71062239.X |
0.624 |
|
| 1998 |
George SR, Lee SP, Varghese G, Zeman PR, Seeman P, Ng GYK, O'Dowd BF. A transmembrane domain-derived peptide inhibits D1 dopamine receptor function without affecting receptor oligomerization Journal of Biological Chemistry. 273: 30244-30248. PMID 9804783 DOI: 10.1074/Jbc.273.46.30244 |
0.52 |
|
| 1998 |
El-Ghundi M, George SR, Drago J, Fletcher PJ, Fan T, Nguyen T, Liu C, Sibley DR, Westphal H, O'Dowd BF. Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior. European Journal of Pharmacology. 353: 149-58. PMID 9726645 DOI: 10.1016/S0014-2999(98)00414-2 |
0.822 |
|
| 1998 |
Marchese A, Nguyen T, Malik P, Xu S, Cheng R, Xie Z, Heng HH, George SR, Kolakowski LF, O'Dowd BF. Cloning genes encoding receptors related to chemoattractant receptors. Genomics. 50: 281-6. PMID 9653656 DOI: 10.1006/Geno.1998.5297 |
0.672 |
|
| 1998 |
Thompson M, Comings DE, Feder L, George SR, O'Dowd BF. Mutation screening of the dopamine D1 receptor gene in Tourette's syndrome and alcohol dependent patients American Journal of Medical Genetics - Neuropsychiatric Genetics. 81: 241-244. PMID 9603612 DOI: 10.1002/(Sici)1096-8628(19980508)81:3<241::Aid-Ajmg7>3.0.Co;2-Z |
0.601 |
|
| 1998 |
Jin H, Nip S, O'Dowd BF, George SR. D1 dopamine receptor activity is not altered by a mutation in the first intracellular loop Biochimica Et Biophysica Acta - Molecular Cell Research. 1402: 165-170. PMID 9561802 DOI: 10.1016/S0167-4889(97)00159-6 |
0.739 |
|
| 1998 |
O'Dowd BF, Nguyen T, Marchese A, Cheng R, Lynch KR, Heng HH, Kolakowski LF, George SR. Discovery of three novel G-protein-coupled receptor genes. Genomics. 47: 310-3. PMID 9479505 DOI: 10.1006/Geno.1998.5095 |
0.665 |
|
| 1997 |
Sawzdargo M, George SR, Nguyen T, Xu S, Kolakowski LF, O'dowd BF. A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1 Biochemical and Biophysical Research Communications. 239: 543-547. PMID 9344866 DOI: 10.1006/Bbrc.1997.7513 |
0.604 |
|
| 1997 |
Ng GYK, Varghese G, Chung HT, Trogadis J, Seeman P, O'Dowd BF, George SR. Resistance of the dopamine D2(L) receptor to desensitization accompanies the up-regulation of receptors on to the surface of Sf9 cells Endocrinology. 138: 4199-4206. PMID 9322930 DOI: 10.1210/endo.138.10.5433 |
0.509 |
|
| 1997 |
Pak Y, O'Dowd BF, George SR. Agonist-induced desensitization of the μ opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail Journal of Biological Chemistry. 272: 24961-24965. PMID 9312100 DOI: 10.1074/Jbc.272.40.24961 |
0.453 |
|
| 1997 |
Jin H, Zastawny R, George SR, O'Dowd BF. Elimination of palmitoylation sites in the human dopamine D1 receptor does not affect receptor-G protein interaction European Journal of Pharmacology. 324: 109-116. PMID 9137920 DOI: 10.1016/S0014-2999(97)00059-9 |
0.768 |
|
| 1997 |
O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF, Lynch KR, George SR. Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes. Gene. 187: 75-81. PMID 9073069 DOI: 10.1016/S0378-1119(96)00722-6 |
0.641 |
|
| 1997 |
Jung BP, Nguyen T, Kolakowski LF, Lynch KR, Heng HHQ, George SR, O'Dowd BF. Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1 Biochemical and Biophysical Research Communications. 230: 69-72. PMID 9020062 DOI: 10.1006/Bbrc.1996.5828 |
0.701 |
|
| 1997 |
Kolakqwsk LF, Casares J, Marchese A, Johnson MP, Nguyen T, Lynch KR, George SR, O'Dowd B. Discovery, cloning, and characterization of a novel human G protein-coupled receptor genes Faseb Journal. 11: A1339. |
0.338 |
|
| 1996 |
Kolakowski LF, Jung BP, Nguyen T, Johnson MP, Lynch KR, Cheng R, Heng HHQ, George SR, O'Dowd BF. Characterization of a human gene related to genes encoding somatostatin receptors Febs Letters. 398: 253-258. PMID 8977118 DOI: 10.1016/S0014-5793(96)01160-X |
0.665 |
|
| 1996 |
Pak Y, Kouvelas A, Scheideler MA, Rasmussen J, O'Dowd BF, George SR. Agonist-induced functional desensitization of the μ-opioid receptor is mediated by loss of membrane receptors rather than uncoupling from G protein Molecular Pharmacology. 50: 1214-1222. PMID 8913353 |
0.415 |
|
| 1996 |
Ng GYK, O'Dowd BF, George SR. Genotypic differences in mesolimbic enkephalin gene expression DBA/2J and C57BL/6J inbred mice European Journal of Pharmacology. 311: 45-52. PMID 8884235 DOI: 10.1016/0014-2999(96)00401-3 |
0.613 |
|
| 1996 |
Ng GYK, O'Dowd BF, Lee SP, Chung HT, Brann MR, Seeman P, George SR. Dopamine D2 receptor dimers and receptor-blocking peptides Biochemical and Biophysical Research Communications. 227: 200-204. PMID 8858125 DOI: 10.1006/Bbrc.1996.1489 |
0.759 |
|
| 1996 |
Heiber M, Marchese A, Nguyen T, Heng HH, George SR, O'Dowd BF. A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. Genomics. 32: 462-5. PMID 8838812 DOI: 10.1006/Geno.1996.0143 |
0.718 |
|
| 1996 |
O'Dowd BF, Nguyen T, Lynch KR, Kolakowski LF, Thompson M, Cheng R, Marchese A, Ng G, Heng HH, George SR. A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain. Febs Letters. 394: 325-9. PMID 8830667 DOI: 10.1016/0014-5793(96)00901-5 |
0.739 |
|
| 1996 |
Lam S, Shen Y, Nguyen T, Messier TL, Brann M, Comings D, George SR, O'Dowd BF. A serotonin receptor gene (5HT1A) variant found in a Tourette's Syndrome patient Biochemical and Biophysical Research Communications. 219: 853-858. PMID 8645269 DOI: 10.1006/Bbrc.1996.0322 |
0.683 |
|
| 1995 |
Nguyen T, Erb L, Weisman GA, Marchese A, Heng HH, Garrad RC, George SR, Turner JT, O'Dowd BF. Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene. The Journal of Biological Chemistry. 270: 30845-8. PMID 8537335 DOI: 10.1074/Jbc.270.52.30845 |
0.703 |
|
| 1995 |
Marchese A, Beischlag TV, Nguyen T, Niznik HB, Weinshank RL, George SR, O'Dowd BF. Two gene duplication events in the human and primate dopamine D5 receptor gene family. Gene. 154: 153-8. PMID 7890157 DOI: 10.1016/0378-1119(94)00879-W |
0.686 |
|
| 1995 |
Bard JA, Nawoschik SP, O'Dowd BF, George SR, Branchek TA, Weinshank RL. The human serotonin 5-hydroxytryptamine1D receptor pseudogene is transcribed Gene. 153: 295-296. PMID 7875610 DOI: 10.1016/0378-1119(94)00693-M |
0.596 |
|
| 1995 |
Heiber M, Docherty JM, Shah G, Nguyen T, Cheng R, Heng HH, Marchese A, Tsui LC, Shi X, George SR. Isolation of three novel human genes encoding G protein-coupled receptors. Dna and Cell Biology. 14: 25-35. PMID 7832990 DOI: 10.1089/Dna.1995.14.25 |
0.46 |
|
| 1995 |
Trogadis JE, Ng GYK, O'Dowd BF, George SR, Stevens JK. Dopamine D1 receptor distribution in Sf9 cells imaged by confocal microscopy: A quantitative evaluation Journal of Histochemistry and Cytochemistry. 43: 497-506. PMID 7730588 |
0.48 |
|
| 1995 |
Ng GY, Trogadis J, Stevens J, Bouvier M, O'Dowd BF, George SR. Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and biochemically separated from D1 receptor internalization. Proceedings of the National Academy of Sciences of the United States of America. 92: 10157-61. PMID 7479745 DOI: 10.1073/Pnas.92.22.10157 |
0.776 |
|
| 1994 |
Zastawny RL, George SR, Nguyen T, Cheng R, Tsatsos J, Briones-Urbina R, O'Dowd BF. Cloning, characterization, and distribution of a μ-opioid receptor in rat brain Journal of Neurochemistry. 62: 2099-2105. PMID 8189219 DOI: 10.1046/J.1471-4159.1994.62062099.X |
0.677 |
|
| 1994 |
Laurier LG, Corrigall WA, George SR. Dopamine receptor density, sensitivity and mRNA levels are altered following self-administration of cocaine in the rat Brain Research. 634: 31-40. PMID 8156390 DOI: 10.1016/0006-8993(94)90255-0 |
0.551 |
|
| 1994 |
Ren WZ, Ng GYK, Wang RX, Wu PH, O'Dowd BF, Osmond DH, George SR, Liew CC. The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations Molecular Brain Research. 22: 173-185. PMID 8015377 DOI: 10.1016/0169-328X(94)90045-0 |
0.561 |
|
| 1994 |
Ng GYK, O'Dowd BF, Caron M, Dennis M, Brann MR, George SR. Phosphorylation and palmitoylation of the human D2L dopamine receptor in Sf9 cells Journal of Neurochemistry. 63: 1589-1595. PMID 7931316 DOI: 10.1046/J.1471-4159.1994.63051589.X |
0.74 |
|
| 1994 |
Ng GY, George SR. Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse European Journal of Pharmacology: Molecular Pharmacology. 269: 365-374. PMID 7895775 DOI: 10.1016/0922-4106(94)90044-2 |
0.526 |
|
| 1994 |
Ng GY, O'Dowd BF, George SR. Genotypic differences in brain dopamine receptor function in the DBA/2J and C57BL/6J inbred mouse strains European Journal of Pharmacology: Molecular Pharmacology. 269: 349-364. PMID 7895774 DOI: 10.1016/0922-4106(94)90043-4 |
0.745 |
|
| 1994 |
Marchese A, Docherty JM, Nguyen T, Heiber M, Cheng R, Heng HH, Tsui LC, Shi X, George SR, O'Dowd BF. Cloning of human genes encoding novel G protein-coupled receptors. Genomics. 23: 609-18. PMID 7851889 DOI: 10.1006/Geno.1994.1549 |
0.684 |
|
| 1994 |
Marchese A, Cheng R, Lee MC, Porter CA, Heiber M, Goodman M, George SR, O'Dowd BF. Mapping studies of two G protein-coupled receptor genes: an amino acid difference may confer a functional variation between a human and rodent receptor. Biochemical and Biophysical Research Communications. 205: 1952-8. PMID 7811287 DOI: 10.1006/Bbrc.1994.2899 |
0.451 |
|
| 1994 |
Laurier LG, O'Dowd BF, George SR. Heterogeneous tissue-specific transcription of dopamine receptor subtype messenger RNA in rat brain Molecular Brain Research. 25: 344-350. PMID 7808233 DOI: 10.1016/0169-328X(94)90170-8 |
0.739 |
|
| 1994 |
George SR, Zastawny RL, Brionesurbina R, Cheng R, Nguyen T, Heiber M, Kouvelas A, Chan AS, Odowd BF. Distinct Distributions of Mu, Delta and Kappa Opioid Receptor mRNA in Rat Brain Biochemical and Biophysical Research Communications. 205: 1438-1444. PMID 7802680 DOI: 10.1006/Bbrc.1994.2826 |
0.435 |
|
| 1994 |
Ng GY, Mouillac B, George SR, Caron M, Dennis M, Bouvier M, O'Dowd BF. Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. European Journal of Pharmacology. 267: 7-19. PMID 7515822 DOI: 10.1016/0922-4106(94)90219-4 |
0.753 |
|
| 1993 |
Tomic M, Seeman P, George SR, Odowd BF. Dopamine D1 Receptor Mutagenesis: Role of Amino Acids in Agonist and Antagonist Binding Biochemical and Biophysical Research Communications. 191: 1020-1027. PMID 8466481 DOI: 10.1006/Bbrc.1993.1319 |
0.544 |
|
| 1993 |
O'Dowd BF, Heiber M, Chan A, Heng HHQ, Tsui LC, Kennedy JL, Shi X, Petronis A, George SR, Nguyen T. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11 Gene. 136: 355-360. PMID 8294032 DOI: 10.1016/0378-1119(93)90495-O |
0.677 |
|
| 1993 |
Ng GYK, George SR, Zastawny RL, Caron M, Bouvier M, Dennis M, O'Dowd BF. Human serotonin(1B) receptor expression in Sf9 cells: Phosphorylation, palmitoylation, and adenylyl cyclase inhibition Biochemistry. 32: 11727-11733. PMID 8218242 DOI: 10.1021/Bi00094A032 |
0.644 |
|
| 1993 |
George SR, Cheng R, Nguyen T, Israel Y, Odowd BF. Polymorphisms of the D4 Dopamine Receptor Alleles in Chronic Alcoholism Biochemical and Biophysical Research Communications. 196: 107-114. PMID 8216280 DOI: 10.1006/Bbrc.1993.2222 |
0.489 |
|
| 1992 |
Borgundvaag B, Kudlow JE, Mueller SG, George SR. Dopamine receptor activation inhibits estrogen-stimulated transforming growth factor-α gene expression and growth in anterior pituitary, but not in uterus Endocrinology. 130: 3453-3458. PMID 1534540 DOI: 10.1210/Endo.130.6.1534540 |
0.309 |
|
| 1991 |
Sunahara RK, Guan HC, O'Dowd BF, Seeman P, Laurier LG, Ng G, George SR, Torchia J, Van Tol HHM, Niznik HB. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1 Nature. 350: 614-619. PMID 1826762 DOI: 10.1038/350614A0 |
0.778 |
|
| 1991 |
George SR, Roldan L, Lui A, Naranjo CA. Endogenous opioids are involved in the genetically determined high preference for ethanol consumption Alcoholism: Clinical and Experimental Research. 15: 668-672. PMID 1656811 DOI: 10.1111/J.1530-0277.1991.Tb00576.X |
0.321 |
|
| 1989 |
Borgundvaag B, George SR. Estrogen regulation of rat anterior pituitary adenylate cyclase. Molecular and Cellular Endocrinology. 59: 35-45. PMID 3197919 DOI: 10.1016/0303-7207(88)90193-1 |
0.377 |
|
| 1988 |
Haas DA, George SR. Effect of dopaminergic and alpha-adrenergic modulation on corticotropin-releasing factor immunoreactivity in rat hypothalamus. Canadian Journal of Physiology and Pharmacology. 66: 754-61. PMID 2901903 DOI: 10.1139/Y88-120 |
0.328 |
|
| 1987 |
George SR, Kertesz M. [Met5]enkephalin concentrations in rat pituitary are maintained under opioid inhibition European Journal of Pharmacology. 140: 95-98. PMID 3622625 DOI: 10.1016/0014-2999(87)90638-8 |
0.345 |
|
| 1987 |
George SR, Kertesz M. Met-enkephalin concentrations in striatum respond reciprocally to alterations in dopamine neurotransmission Peptides. 8: 487-492. PMID 2889200 DOI: 10.1016/0196-9781(87)90014-3 |
0.437 |
|
| 1986 |
George SR, Kertesz M. Met-enkephalin-like immunoreactivity in neurointermediate pituitary is decreased by DA receptor stimulation Peptides. 7: 277-281. PMID 3737447 DOI: 10.1016/0196-9781(86)90225-1 |
0.418 |
|
| 1986 |
George SR, Watanabe M, Seeman P. Dopamine D2 receptors in brain and anterior pituitary recognize agonist and antagonist actions of (-)-3-PPP. Journal of Neural Transmission. 64: 13-33. PMID 2933489 DOI: 10.1007/Bf01259342 |
0.609 |
|
| 1985 |
Borgundvaag B, George SR. Dopamine inhibition of anterior pituitary adenylate cyclase is mediated through the high-affinity state of the D2 receptor. Life Sciences. 37: 379-86. PMID 4040201 DOI: 10.1016/0024-3205(85)90509-0 |
0.506 |
|
| 1985 |
George SR, Watanabe M, Di Paolo T, Falardeau P, Labrie F, Seeman P. The functional state of the dopamine receptor in the anterior pituitary is in the high affinity form. Endocrinology. 117: 690-7. PMID 4017954 DOI: 10.1210/Endo-117-2-690 |
0.346 |
|
| 1985 |
Watanabe M, George SR, Seeman P. Dependence of dopamine receptor conversion from agonist high- to low-affinity state on temperature and sodium ions. Biochemical Pharmacology. 34: 2459-63. PMID 4015688 DOI: 10.1016/0006-2952(85)90526-X |
0.371 |
|
| 1985 |
George SR, Kertesz M. Dopamine receptors regulate Met-enkephalin content in pituitary Brain Research. 334: 187-189. PMID 2986780 DOI: 10.1016/0006-8993(85)90586-4 |
0.527 |
|
| 1985 |
Watanabe M, George SR, Seeman P. Regulation of anterior pituitary D2 dopamine receptors by magnesium and sodium ions. Journal of Neurochemistry. 45: 1842-9. PMID 2932536 DOI: 10.1111/J.1471-4159.1985.Tb10542.X |
0.565 |
|
| 1985 |
George SR, Watanabe M, Seeman P. Dopamine D2 receptors in the anterior pituitary: a single population without reciprocal antagonist/agonist states. Journal of Neurochemistry. 44: 1168-77. PMID 2579204 DOI: 10.1111/J.1471-4159.1985.Tb08740.X |
0.499 |
|
| 1983 |
Van Loon GR, Shum A, George SR, Shin SH. Prolactin increases the activity of tuberoinfundibular and nigroneostriatal dopamine neurons: Prolactin antiserum inhibits the haloperidol-induced increases in dopamine synthesis rates in median eminence and striatum of rats Brain Research Bulletin. 10: 539-545. PMID 6860978 DOI: 10.1016/0361-9230(83)90152-1 |
0.374 |
|
| 1983 |
George S, Binkley K, Seeman P. Dopamine receptor sites and states in human brain. Journal of Neural Transmission-Supplement. 18: 149-156. DOI: 10.1007/978-3-7091-4408-4_14 |
0.478 |
|
| 1982 |
George SR, Van Loon GR. Characterization of high affinity dopamine uptake into the dopamine neurons of the hypothalamus Brain Research. 234: 339-355. PMID 7059835 DOI: 10.1016/0006-8993(82)90874-5 |
0.313 |
|
| 1982 |
George SR, Van Loon GR. β-endorphin alters dopamine uptake by the dopamine neurons of the hypothalamus and striatum Brain Research. 248: 293-303. PMID 6291701 DOI: 10.1016/0006-8993(82)90587-X |
0.391 |
|
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