Carmelo Rizzo - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Organic Chemistry, Pharmaceutical Chemistry

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ghodke PP, Mali JR, Patra A, Rizzo CJ, Guengerich FP, Egli M. Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N-ethenodeoxyguanosine by human DNA translesion polymerase η. The Journal of Biological Chemistry. 100642. PMID 33839151 DOI: 10.1016/j.jbc.2021.100642  0.48
2020 Chen H, Cui Z, Hejazi L, Yao L, Walmsley SJ, Rizzo CJ, Turesky RJ. Kinetics of DNA Adducts and Abasic Site Formation in Tissues of Mice Treated with a Nitrogen Mustard. Chemical Research in Toxicology. PMID 32174110 DOI: 10.1021/Acs.Chemrestox.0C00012  0.32
2019 Chen H, Yao L, Brown C, Rizzo CJ, Turesky RJ. Quantitation of Apurinic/Apyrimidinic Sites in Isolated DNA and in Mammalian Tissue with Reduced Artifact. Analytical Chemistry. PMID 31055913 DOI: 10.1021/acs.analchem.9b01351  0.32
2018 Bamberger SN, Malik CK, Voehler MW, Brown SK, Pan H, Johnson-Salyard TL, Rizzo CJ, Stone MP. Configurational and Conformational Equilibria of N-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5- N-methylformamidopyrimidine (MeFapy-dG) Lesion in DNA. Chemical Research in Toxicology. PMID 30169026 DOI: 10.1021/acs.chemrestox.8b00135  0.68
2016 Bose A, Millsap AD, DeLeon A, Rizzo CJ, Basu AK. Translesion synthesis of the N(2)-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells: Error-free replication by DNA polymerase κ and mutagenic bypass by DNA polymerases η, ζ, and Rev1. Chemical Research in Toxicology. PMID 27490094 DOI: 10.1021/Acs.Chemrestox.6B00221  0.32
2016 Minko IG, Jacobs AC, de Leon AR, Gruppi F, Donley N, Harris TM, Rizzo CJ, McCullough AK, Lloyd RS. Catalysts of DNA Strand Cleavage at Apurinic/Apyrimidinic Sites. Scientific Reports. 6: 28894. PMID 27363485 DOI: 10.1038/Srep28894  0.4
2015 Gruppi F, Hejazi L, Christov PP, Krishnamachari S, Turesky RJ, Rizzo CJ. Characterization of nitrogen mustard formamidopyrimidine adduct formation of bis(2-chloroethyl)ethylamine with calf thymus DNA and a human mammary cancer cell line. Chemical Research in Toxicology. 28: 1850-60. PMID 26285869 DOI: 10.1021/Acs.Chemrestox.5B00297  0.32
2015 Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK. DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells. Nucleic Acids Research. PMID 26220181 DOI: 10.1093/Nar/Gkv750  0.32
2015 Stavros KM, Hawkins EK, Rizzo CJ, Stone MP. Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA Adduct Positioned at the Nonreiterated G(1) in the NarI Restriction Site. Chemical Research in Toxicology. 28: 1455-68. PMID 26083477 DOI: 10.1021/acs.chemrestox.5b00140  0.68
2015 Patra A, Banerjee S, Johnson Salyard TL, Malik CK, Christov PP, Rizzo CJ, Stone MP, Egli M. Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV. Journal of the American Chemical Society. 137: 7011-4. PMID 25988947 DOI: 10.1021/Jacs.5B02701  0.68
2015 Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, et al. Next-generation sequencing reveals the biological significance of the N2,3-ethenoguanine lesion in vivo. Nucleic Acids Research. 43: 5489-500. PMID 25837992 DOI: 10.1093/Nar/Gkv243  0.32
2015 Zdżalik D, Domańska A, Prorok P, Kosicki K, van den Born E, Falnes PØ, Rizzo CJ, Guengerich FP, Tudek B. Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins. Dna Repair. 30: 1-10. PMID 25797601 DOI: 10.1016/J.Dnarep.2015.02.021  0.32
2015 Brennan FP, Branner K, Den Besten JH, Horn AM, Ki Choi B, Mao W, Nakamura T, Oterkus E, Paranhos Pasqualino I, Parmentier G, Rizzo C, Romanoff J, Rörup J, Samanta A, Theodoulidis A, et al. Fatigue and fracture Proceedings of the 19th International Ship and Offshore Structures Congress, Issc 2015. 1: 351-413.  0.68
2014 Gruppi F, Johnson Salyard TL, Rizzo CJ. Synthesis of G-N2-(CH2)3-N2-G Trimethylene DNA Interstrand Cross-Links. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. 56: 5.14.1-15. PMID 25606979 DOI: 10.1002/0471142700.nc0514s56  1
2014 Gruppi F, Salyard TL, Rizzo CJ. Synthesis of G-N (2)-(CH2)3-N (2)-G Trimethylene DNA interstrand cross-links. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. 5: 5.14.1-5.14.15. PMID 25431636 DOI: 10.1002/0471142700.nc0514s56  0.4
2014 Singh V, Fedeles BI, Li D, Delaney JC, Kozekov ID, Kozekova A, Marnett LJ, Rizzo CJ, Essigmann JM. Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB. Chemical Research in Toxicology. 27: 1619-31. PMID 25157679 DOI: 10.1021/Tx5002817  1
2014 Christov PP, Son KJ, Rizzo CJ. Synthesis and characterization of oligonucleotides containing a nitrogen mustard formamidopyrimidine monoadduct of deoxyguanosine. Chemical Research in Toxicology. 27: 1610-8. PMID 25136769 DOI: 10.1021/Tx5002354  1
2014 Petrova KV, Millsap AD, Stec DF, Rizzo CJ. Characterization of the deoxyguanosine-lysine cross-link of methylglyoxal. Chemical Research in Toxicology. 27: 1019-29. PMID 24801980 DOI: 10.1021/tx500068v  1
2014 Stavros KM, Hawkins EK, Rizzo CJ, Stone MP. Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI DNA recognition sequence. Nucleic Acids Research. 42: 3450-63. PMID 24366876 DOI: 10.1093/nar/gkt1109  1
2013 Maddukuri L, Shuck SC, Eoff RL, Zhao L, Rizzo CJ, Guengerich FP, Marnett LJ. Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine. Biochemistry. 52: 8766-76. PMID 24171480 DOI: 10.1021/Bi401103K  1
2013 Shell SM, Hawkins EK, Tsai MS, Hlaing AS, Rizzo CJ, Chazin WJ. Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DNA. Dna Repair. 12: 947-53. PMID 24051049 DOI: 10.1016/J.Dnarep.2013.08.013  1
2013 Shanmugam G, Minko IG, Banerjee S, Christov PP, Kozekov ID, Rizzo CJ, Lloyd RS, Egli M, Stone MP. Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4. Chemical Research in Toxicology. 26: 1348-60. PMID 23947567 DOI: 10.1021/Tx400200B  1
2013 Christov PP, Hawkins EK, Kett NR, Rizzo CJ. Simplified synthesis of individual stereoisomers of the 4-hydroxynonenal adducts of deoxyguanosine. Tetrahedron Letters. 54: 4289-4291. PMID 23935223 DOI: 10.1016/J.Tetlet.2013.06.004  1
2013 Earley LF, Minko IG, Christov PP, Rizzo CJ, Lloyd RS. Mutagenic spectra arising from replication bypass of the 2,6-diamino-4-hydroxy-N(5)-methyl formamidopyrimidine adduct in primate cells. Chemical Research in Toxicology. 26: 1108-14. PMID 23763662 DOI: 10.1021/Tx4001495  1
2012 Zhao L, Pence MG, Christov PP, Wawrzak Z, Choi JY, Rizzo CJ, Egli M, Guengerich FP. Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases. The Journal of Biological Chemistry. 287: 35516-26. PMID 22910910 DOI: 10.1074/Jbc.M112.403253  1
2012 Christov PP, Yamanaka K, Choi JY, Takata K, Wood RD, Guengerich FP, Lloyd RS, Rizzo CJ. Replication of the 2,6-diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases. Chemical Research in Toxicology. 25: 1652-61. PMID 22721435 DOI: 10.1021/Tx300113E  1
2012 Zhao L, Christov PP, Kozekov ID, Pence MG, Pallan PS, Rizzo CJ, Egli M, Guengerich FP. Replication of N2,3-ethenoguanine by DNA polymerases. Angewandte Chemie (International Ed. in English). 51: 5466-9. PMID 22488769 DOI: 10.1002/Anie.201109004  1
2012 Banerjee S, Christov PP, Kozekova A, Rizzo CJ, Egli M, Stone MP. Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chemical Research in Toxicology. 25: 422-35. PMID 22313351 DOI: 10.1021/Tx200460J  1
2011 Harris CM, Stec DF, Christov PP, Kozekov ID, Rizzo CJ, Harris TM. Deoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzene. Chemical Research in Toxicology. 24: 1944-56. PMID 21972945 DOI: 10.1021/Tx2002838  1
2011 Huang H, Wang H, Kozekova A, Rizzo CJ, Stone MP. Formation of a N2-dG:N2-dG carbinolamine DNA cross-link by the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N2-dG adduct. Journal of the American Chemical Society. 133: 16101-10. PMID 21916419 DOI: 10.1021/ja205145q  0.68
2011 Shanmugam G, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP. 1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine. Chemical Research in Toxicology. 24: 1071-9. PMID 21675798 DOI: 10.1021/Tx200089V  0.68
2011 Polavarapu PL, Donahue EA, Shanmugam G, Scalmani G, Hawkins EK, Rizzo C, Ibnusaud I, Thomas G, Habel D, Sebastian D. A single chiroptical spectroscopic method may not be able to establish the absolute configurations of diastereomers: dimethylesters of hibiscus and garcinia acids. The Journal of Physical Chemistry. A. 115: 5665-73. PMID 21568330 DOI: 10.1021/Jp202501Y  1
2011 Huang H, Wang H, Voehler MW, Kozekova A, Rizzo CJ, McCullough AK, Lloyd RS, Stone MP. γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage. Chemical Research in Toxicology. 24: 1123-33. PMID 21561113 DOI: 10.1021/tx200113n  1
2011 Polavarapu PL, Scalmani G, Hawkins EK, Rizzo C, Jeirath N, Ibnusaud I, Habel D, Nair DS, Haleema S. Importance of solvation in understanding the chiroptical spectra of natural products in solution phase: garcinia acid dimethyl ester. Journal of Natural Products. 74: 321-8. PMID 21114277 DOI: 10.1021/Np100512W  1
2010 Kozekov ID, Turesky RJ, Alas GR, Harris CM, Harris TM, Rizzo CJ. Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal. Chemical Research in Toxicology. 23: 1701-13. PMID 20964440 DOI: 10.1021/Tx100179G  1
2010 Christov PP, Banerjee S, Stone MP, Rizzo CJ. Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV. Journal of Nucleic Acids. 2010. PMID 20798848 DOI: 10.4061/2010/850234  1
2010 Maddukuri L, Eoff RL, Choi JY, Rizzo CJ, Guengerich FP, Marnett LJ. In vitro bypass of the major malondialdehyde- and base propenal-derived DNA adduct by human Y-family DNA polymerases κ, ι, and Rev1. Biochemistry. 49: 8415-24. PMID 20726503 DOI: 10.1021/Bi1009024  1
2010 Huang H, Kozekov ID, Kozekova A, Rizzo CJ, McCullough AK, Lloyd RS, Stone MP. Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage. Biochemistry. 49: 6155-64. PMID 20604523 DOI: 10.1021/bi100364f  1
2010 Christov PP, Petrova KV, Shanmugam G, Kozekov ID, Kozekova A, Guengerich FP, Stone MP, Rizzo CJ. Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). Chemical Research in Toxicology. 23: 1330-41. PMID 20578729 DOI: 10.1021/Tx100082E  1
2010 Huang H, Kozekov ID, Kozekova A, Wang H, Lloyd RS, Rizzo CJ, Stone MP. DNA cross-link induced by trans-4-hydroxynonenal. Environmental and Molecular Mutagenesis. 51: 625-34. PMID 20577992 DOI: 10.1002/em.20599  0.68
2010 Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro. Chemical Research in Toxicology. 23: 1076-88. PMID 20377178 DOI: 10.1021/Tx100053N  1
2010 Shanmugam G, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP. Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion. Biochemistry. 49: 2615-26. PMID 20201499 DOI: 10.1021/Bi901516D  0.68
2010 Liu M, Bandaru V, Bond JP, Jaruga P, Zhao X, Christov PP, Burrows CJ, Rizzo CJ, Dizdaroglu M, Wallace SS. The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo Proceedings of the National Academy of Sciences of the United States of America. 107: 4925-4930. PMID 20185759 DOI: 10.1073/Pnas.0908307107  1
2010 Yamanaka K, Minko IG, Takata K, Kolbanovskiy A, Kozekov ID, Wood RD, Rizzo CJ, Lloyd RS. Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Chemical Research in Toxicology. 23: 689-95. PMID 20102227 DOI: 10.1021/Tx900449U  0.36
2010 Stone MP, Huang H, Cho YJ, Kim HY, Kozekov ID, Kozekova A, Wang H, Harris TM, Rizzo CJ, Minko IG, Lloyd RS. Interstrand DNA Cross-Linking 1, N 2-Deoxyguanosine Adducts Derived from α,β-Unsaturated Aldehydes: Structure-Function Relationships The Chemical Biology of Dna Damage. 201-216. DOI: 10.1002/9783527630110.ch9  1
2009 Ben-Yehoyada M, Wang LC, Kozekov ID, Rizzo CJ, Gottesman ME, Gautier J. Checkpoint signaling from a single DNA interstrand crosslink. Molecular Cell. 35: 704-15. PMID 19748363 DOI: 10.1016/J.Molcel.2009.08.014  1
2009 Zhang H, Bren U, Kozekov ID, Rizzo CJ, Stec DF, Guengerich FP. Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Journal of Molecular Biology. 392: 251-69. PMID 19607842 DOI: 10.1016/J.Jmb.2009.07.019  0.48
2009 Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP. Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes. The Journal of Biological Chemistry. 284: 17687-99. PMID 19542237 DOI: 10.1074/Jbc.M109014274  1
2009 Huang H, Kim HY, Kozekov ID, Cho YJ, Wang H, Kozekova A, Harris TM, Rizzo CJ, Stone MP. Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence. Journal of the American Chemical Society. 131: 8416-24. PMID 19530727 DOI: 10.1021/Ja809543J  1
2009 Eoff RL, Stafford JB, Szekely J, Rizzo CJ, Egli M, Guengerich FP, Marnett LJ. Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Biochemistry. 48: 7079-88. PMID 19492857 DOI: 10.1021/Bi9003588  1
2009 Christov PP, Angel KC, Guengerich FP, Rizzo CJ. Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry. Chemical Research in Toxicology. 22: 1086-95. PMID 19397282 DOI: 10.1021/Tx900047C  1
2009 Minko IG, Kozekov ID, Harris TM, Rizzo CJ, Lloyd RS, Stone MP. Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chemical Research in Toxicology. 22: 759-78. PMID 19397281 DOI: 10.1021/Tx9000489  1
2009 Knutson CG, Rubinson EH, Akingbade D, Anderson CS, Stec DF, Petrova KV, Kozekov ID, Guengerich FP, Rizzo CJ, Marnett LJ. Oxidation and glycolytic cleavage of etheno and propano DNA base adducts. Biochemistry. 48: 800-9. PMID 19132922 DOI: 10.1021/Bi801654J  1
2009 Stafford JB, Eoff RL, Kozekova A, Rizzo CJ, Guengerich FP, Marnett LJ. Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one. Biochemistry. 48: 471-80. PMID 19108641 DOI: 10.1021/Bi801591A  1
2009 Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP. Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts. The Journal of Biological Chemistry. 284: 3563-76. PMID 19059910 DOI: 10.1074/Jbc.M807778200  1
2009 Huang H, Wang H, Lloyd RS, Rizzo CJ, Stone MP. Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA. Chemical Research in Toxicology. 22: 187-200. PMID 19053179 DOI: 10.1021/tx800320m  0.68
2008 Christov PP, Brown KL, Kozekov ID, Stone MP, Harris TM, Rizzo CJ. Site-specific synthesis and characterization of oligonucleotides containing an N6-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine lesion, the ring-opened product from N7-methylation of deoxyguanosine. Chemical Research in Toxicology. 21: 2324-33. PMID 19053322 DOI: 10.1021/Tx800352A  1
2008 Huang H, Wang H, Qi N, Lloyd RS, Rizzo CJ, Stone MP. The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Biochemistry. 47: 11457-72. PMID 18847226 DOI: 10.1021/Bi8011143  0.68
2008 Minko IG, Yamanaka K, Kozekov ID, Kozekova A, Indiani C, O'Donnell ME, Jiang Q, Goodman MF, Rizzo CJ, Lloyd RS. Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Chemical Research in Toxicology. 21: 1983-90. PMID 18788757 DOI: 10.1021/Tx800174A  1
2008 Shanmugam G, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP. Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2. Chemical Research in Toxicology. 21: 1795-805. PMID 18693701 DOI: 10.1021/Tx8001466  0.68
2008 Christov PP, Kozekov ID, Rizzo CJ, Harris TM. The formamidopyrimidine derivative of 7-(2-oxoethyl)-2'-deoxyguanosine. Chemical Research in Toxicology. 21: 1777-86. PMID 18690723 DOI: 10.1021/Tx800142M  1
2008 Huang H, Wang H, Qi N, Kozekova A, Rizzo CJ, Stone MP. Rearrangement of the (6S,8R,11S) and (6R,8S,11R) exocyclic 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal to N2-deoxyguanosine cyclic hemiacetal adducts when placed complementary to cytosine in duplex DNA. Journal of the American Chemical Society. 130: 10898-906. PMID 18661996 DOI: 10.1021/Ja801824B  0.68
2008 Dexheimer TS, Kozekova A, Rizzo CJ, Stone MP, Pommier Y. The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts. Nucleic Acids Research. 36: 4128-36. PMID 18550580 DOI: 10.1093/nar/gkn334  1
2008 Stone MP, Cho YJ, Huang H, Kim HY, Kozekov ID, Kozekova A, Wang H, Minko IG, Lloyd RS, Harris TM, Rizzo CJ. Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources. Accounts of Chemical Research. 41: 793-804. PMID 18500830 DOI: 10.1021/Ar700246X  1
2008 Minko IG, Harbut MB, Kozekov ID, Kozekova A, Jakobs PM, Olson SB, Moses RE, Harris TM, Rizzo CJ, Lloyd RS. Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links. The Journal of Biological Chemistry. 283: 17075-82. PMID 18434313 DOI: 10.1074/Jbc.M801238200  1
2008 Szekely J, Rizzo CJ, Marnett LJ. Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation. Journal of the American Chemical Society. 130: 2195-201. PMID 18225895 DOI: 10.1021/Ja074506U  1
2008 Szekely J, Wang H, Peplowski KM, Knutson CG, Marnett LJ, Rizzo CJ. "One-pot" syntheses of malondialdehyde adducts of nucleosides. Nucleosides, Nucleotides & Nucleic Acids. 27: 103-9. PMID 18205065 DOI: 10.1080/15257770701795797  1
2008 Minko IG, Kozekov ID, Kozekova A, Harris TM, Rizzo CJ, Lloyd RS. Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts. Mutation Research. 637: 161-72. PMID 17868748 DOI: 10.1016/J.Mrfmmm.2007.08.001  1
2007 Knutson CG, Wang H, Rizzo CJ, Marnett LJ. Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-β-D-erythropentofuranosyl)-pyrimido[1,2-α]purine-10(3H) -one, in the rat Journal of Biological Chemistry. 282: 36257-36264. PMID 17951255 DOI: 10.1074/Jbc.M706814200  1
2007 Shanmugam G, Goodenough AK, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP. Structure of the 1,N2-etheno-2'-deoxyguanosine adduct in duplex DNA at pH 8.6. Chemical Research in Toxicology. 20: 1601-11. PMID 17941687 DOI: 10.1021/Tx7001788  1
2007 Stover JS, Rizzo CJ. Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline. Chemical Research in Toxicology. 20: 1972-9. PMID 17914884 DOI: 10.1021/Tx7002867  1
2007 Petrova KV, Jalluri RS, Kozekov ID, Rizzo CJ. Mechanism of 1,N2-etheno-2'-deoxyguanosine formation from epoxyaldehydes. Chemical Research in Toxicology. 20: 1685-92. PMID 17907786 DOI: 10.1021/tx7001433  1
2007 Wang F, Elmquist CE, Stover JS, Rizzo CJ, Stone MP. DNA sequence modulates the conformation of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme. Biochemistry. 46: 8498-516. PMID 17602664 DOI: 10.1021/Bi700361U  1
2007 Elmquist CE, Wang F, Stover JS, Stone MP, Rizzo CJ. Conformational differences of the C8-deoxyguanosine adduct of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) within the NarI recognition sequence. Chemical Research in Toxicology. 20: 445-54. PMID 17311423 DOI: 10.1021/Tx060229D  1
2007 Cho YJ, Kozekov ID, Harris TM, Rizzo CJ, Stone MP. Stereochemistry modulates the stability of reduced interstrand cross-links arising from R- and S-alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence. Biochemistry. 46: 2608-21. PMID 17305317 DOI: 10.1021/Bi061381H  1
2007 Stover JS, Ciobanu M, Cliffel DE, Rizzo CJ. Chemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosine. Journal of the American Chemical Society. 129: 2074-81. PMID 17256856 DOI: 10.1021/Ja066404U  1
2006 Stover JS, Chowdhury G, Zang H, Guengerich FP, Rizzo CJ. Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases. Chemical Research in Toxicology. 19: 1506-17. PMID 17112239 DOI: 10.1021/Tx0601455  1
2006 Wang H, Kozekov ID, Kozekova A, Tamura PJ, Marnett LJ, Harris TM, Rizzo CJ. Site-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy. Chemical Research in Toxicology. 19: 1467-74. PMID 17112234 DOI: 10.1021/Tx060137O  1
2006 Cho YJ, Wang H, Kozekov ID, Kozekova A, Kurtz AJ, Jacob J, Voehler M, Smith J, Harris TM, Rizzo CJ, Lloyd RS, Stone MP. Orientation of the crotonaldehyde-derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA adduct hinders interstrand cross-link formation in the 5'-CpG-3' sequence. Chemical Research in Toxicology. 19: 1019-29. PMID 16918240 DOI: 10.1021/Tx0600604  1
2006 Wang F, DeMuro NE, Elmquist CE, Stover JS, Rizzo CJ, Stone MP. Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions. Journal of the American Chemical Society. 128: 10085-95. PMID 16881637 DOI: 10.1021/Ja062004V  1
2006 Choi JY, Stover JS, Angel KC, Chowdhury G, Rizzo CJ, Guengerich FP. Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. The Journal of Biological Chemistry. 281: 25297-306. PMID 16835218 DOI: 10.1074/Jbc.M605699200  1
2006 Choi JY, Zang H, Angel KC, Kozekov ID, Goodenough AK, Rizzo CJ, Guengerich FP. Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases. Chemical Research in Toxicology. 19: 879-86. PMID 16780368 DOI: 10.1021/Tx060051V  1
2006 Otteneder MB, Knutson CG, Daniels JS, Hashim M, Crews BC, Remmel RP, Wang H, Rizzo C, Marnett LJ. In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG Proceedings of the National Academy of Sciences of the United States of America. 103: 6665-6669. PMID 16614064 DOI: 10.1073/Pnas.0602017103  1
2006 Cho YJ, Wang H, Kozekov ID, Kurtz AJ, Jacob J, Voehler M, Smith J, Harris TM, Lloyd RS, Rizzo CJ, Stone MP. Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence. Chemical Research in Toxicology. 19: 195-208. PMID 16485895 DOI: 10.1021/Tx050239Z  1
2005 Cho YJ, Kim HY, Huang H, Slutsky A, Minko IG, Wang H, Nechev LV, Kozekov ID, Kozekova A, Tamura P, Jacob J, Voehler M, Harris TM, Lloyd RS, Rizzo CJ, et al. Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct. Journal of the American Chemical Society. 127: 17686-96. PMID 16351098 DOI: 10.1021/Ja053897E  1
2005 Goodenough AK, Kozekov ID, Zang H, Choi JY, Guengerich FP, Harris TM, Rizzo CJ. Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine. Chemical Research in Toxicology. 18: 1701-14. PMID 16300379 DOI: 10.1021/Tx050141K  1
2005 Zang H, Goodenough AK, Choi JY, Irimia A, Loukachevitch LV, Kozekov ID, Angel KC, Rizzo CJ, Egli M, Guengerich FP. DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine. The Journal of Biological Chemistry. 280: 29750-64. PMID 15965231 DOI: 10.1074/Jbc.M504756200  1
2005 Scholdberg TA, Merritt WK, Dean SM, Kowalcyzk A, Harris CM, Harris TM, Rizzo CJ, Lloyd RS, Stone MP. Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence. Biochemistry. 44: 3327-37. PMID 15736943 DOI: 10.1021/Bi0482452  1
2004 Stover JS, Rizzo CJ. Synthesis of the N2-deoxyguanosine adduct of the potent dietary mutagen IQ. Organic Letters. 6: 4985-8. PMID 15606116 DOI: 10.1021/Ol047851M  1
2004 Elmquist CE, Stover JS, Wang Z, Rizzo CJ. Site-specific synthesis and properties of oligonucleotides containing C8-deoxyguanosine adducts of the dietary mutagen IQ. Journal of the American Chemical Society. 126: 11189-201. PMID 15355100 DOI: 10.1021/Ja0487022  1
2004 Brock AK, Kozekov ID, Rizzo CJ, Harris TM. Coupling products of nucleosides with the glyoxal adduct of deoxyguanosine. Chemical Research in Toxicology. 17: 1047-56. PMID 15310236 DOI: 10.1021/Tx049906Z  1
2004 Wang H, Marnett LJ, Harris TM, Rizzo CJ. A novel synthesis of malondialdehyde adducts of deoxyguanosine, deoxyadenosine, and deoxycytidine. Chemical Research in Toxicology. 17: 144-9. PMID 14967001 DOI: 10.1021/Tx034174G  1
2003 Wang H, Kozekov ID, Harris TM, Rizzo CJ. Site-specific synthesis and reactivity of oligonucleotides containing stereochemically defined 1,N2-deoxyguanosine adducts of the lipid peroxidation product trans-4-hydroxynonenal. Journal of the American Chemical Society. 125: 5687-700. PMID 12733907 DOI: 10.1021/Ja0288800  0.36
2003 Kozekov ID, Nechev LV, Moseley MS, Harris CM, Rizzo CJ, Stone MP, Harris TM. DNA interchain cross-links formed by acrolein and crotonaldehyde. Journal of the American Chemical Society. 125: 50-61. PMID 12515506 DOI: 10.1021/Ja020778F  1
2003 Rezaei M, Harris TM, Rizzo CJ. Stereoselective synthesis of the 1,N2-deoxyguanosine adducts of cinnamaldehyde. A stereocontrolled route to deoxyguanosine adducts of α,β-unsaturated aldehydes Tetrahedron Letters. 44: 7513-7516. DOI: 10.1016/J.Tetlet.2003.08.006  1
2002 Nechev LV, Kozekov ID, Brock AK, Rizzo CJ, Harris TM. DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one, an acrolein adduct of guanine. Chemical Research in Toxicology. 15: 607-13. PMID 12018980 DOI: 10.1021/Tx010181Y  0.36
2001 Wang F, Wang H, Polavarapu PL, Rizzo CJ. Absolute configuration and conformational stability of (+)-2,5-dimethylthiolane and (-)-2,5-dimethylsulfolane Journal of Organic Chemistry. 66: 3507-3512. PMID 11348137 DOI: 10.1021/Jo0100401  1
2001 Drabowicz J, Dudziński B, Mikolajczyk M, Wang F, Dehlavi A, Goring J, Park M, Rizzo CJ, Polavarapu PL, Biscarini P, Wieczorek MW, Majzner WR. Absolute configuration, predominant conformations, and vibrational circular dichroism spectra of enantiomers of n-butyl tert-butyl sulfoxide Journal of Organic Chemistry. 66: 1122-1129. PMID 11312938 DOI: 10.1021/Jo0011179  1
2000 Wang Z, Prudhomme DR, Buck JR, Park M, Rizzo CJ. Stereocontrolled syntheses of deoxyribonucleosides via photoinduced electron-transfer deoxygenation of benzoyl-protected ribo- and arabinonucleosides. The Journal of Organic Chemistry. 65: 5969-85. PMID 10987930 DOI: 10.1021/Jo0003652  1
1998 Hasford JJ, Rizzo CJ. Linear free energy substitutent effect on flavin redox chemistry Journal of the American Chemical Society. 120: 2251-2255. DOI: 10.1021/ja972992n  1
1998 Hasford JJ, Rizzo CJ. Reduction of Hg(II)·EDTA by conformationally biased flavins Tetrahedron Letters. 39: 1317-1320. DOI: 10.1016/S0040-4039(98)00001-X  1
1997 Prudhomme DR, Wang Z, Rizzo CJ. An Improved Photosensitizer for the Photoinduced Electron-Transfer Deoxygenation of Benzoates and m-(Trifluoromethyl)benzoates. The Journal of Organic Chemistry. 62: 8257-8260. PMID 11671949 DOI: 10.1021/Jo971332Y  0.52
1996 Park M, Rizzo CJ. Stereocontrolled de Novo Synthesis of beta-2'-Deoxyribonucleosides. The Journal of Organic Chemistry. 61: 6092-6093. PMID 11667437  0.52
1996 Smith AB, Wood JL, Wong W, Gould AE, Rizzo CJ, Barbosa J, Komiyama K, Omura S. (+)-Trienomycins A, B, C, and F and (+)-mycotrienins I and II: Relative and absolute stereochemistry Journal of the American Chemical Society. 118: 8308-8315. DOI: 10.1021/Ja961400I  1
1992 Smith AB, Wood JL, Rizzo CJ, Furst GT, Carroll PJ, Donohue J, Omura S. (+)-Hitachimycin: Stereochemistry and conformational analysis Journal of the American Chemical Society. 114: 8003-8007. DOI: 10.1021/Ja00047A007  1
1992 Rizzo CJ, Dougherty JP, Breslow R. 3′-Deoxy-2′-phosphoramidites of adenosine and 5-methyluridine used for the solid phase synthesis of unnatural 3′-deoxy-2′-5″-Oligonucleotides Tetrahedron Letters. 33: 4129-4132. DOI: 10.1016/S0040-4039(00)74670-3  1
1990 Rizzo CJ, Wood JL, Furst GT, Smith AB. Aphidicolin synthetic studies, 2. 2D NMR analysis of aphidicolin and its degradation products 3α, 18-dihydroxy-17-noraphidicolan-16-one and 3α, 18-isopropylidenedioxy-17-noraphidicolan-16-one Journal of Natural Products. 53: 735-739. DOI: 10.1021/Np50069A037  1
1990 Smith AB, Wood JL, Rizzo CJ, Furst GT, Carroll PJ, Donohue J, Omura S. Solution and crystal structures of (+)-hitachimycin (stubomycin) Journal of Organic Chemistry. 55: 1133-1135. DOI: 10.1021/Jo00291A004  1
1990 Smith AB, Wood JL, Wong W, Gould AE, Rizzo CJ, Funayama S, Omura S. (+)-Trienomycins A, B, and C: Relative and absolute stereochemistry Journal of the American Chemical Society. 112: 7425-7426. DOI: 10.1021/Ja00176A070  1
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