Yufeng J. Tseng, Ph.D. - Publications

Affiliations: 
2002 University of Illinois at Chicago, Health Sciences Center 
Area:
Pharmaceutical Chemistry

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lin FY, Esposito EX, Tseng YJ. LeadOp+R: Structure-Based Lead Optimization With Synthetic Accessibility. Frontiers in Pharmacology. 9: 96. PMID 29556192 DOI: 10.3389/fphar.2018.00096  1
2017 Su BH, Shen MY, Harn YC, Wang SY, Schurz A, Lin C, Lin OA, Tseng YJ. An efficient computer-aided structural elucidation strategy for mixtures using an iterative dynamic programming algorithm. Journal of Cheminformatics. 9: 57. PMID 29143270 DOI: 10.1186/s13321-017-0244-9  0.48
2017 Schurz A, Su BH, Tu YS, Lu TT, Lin OA, Tseng YJ. G.A.M.E.: GPU-accelerated mixture elucidator. Journal of Cheminformatics. 9: 50. PMID 29086161 DOI: 10.1186/s13321-017-0238-7  0.48
2016 Hsu KH, Su BH, Tu YS, Lin OA, Tseng YJ. Mutagenicity in a Molecule: Identification of Core Structural Features of Mutagenicity Using a Scaffold Analysis. Plos One. 11: e0148900. PMID 26863515 DOI: 10.1371/journal.pone.0148900  1
2015 Chen GY, Liao HW, Tsai IL, Tseng YJ, Kuo CH. Using the Matrix-Induced Ion Suppression Method for Concentration Normalization in Cellular Metabolomics Studies. Analytical Chemistry. PMID 26359637 DOI: 10.1021/acs.analchem.5b01869  1
2015 Lai YS, Chen WC, Kuo TC, Ho CT, Kuo CH, Tseng YJ, Lu KH, Lin SH, Panyod S, Sheen LY. Mass-Spectrometry-Based Serum Metabolomics of a C57BL/6J Mouse Model of High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease Development. Journal of Agricultural and Food Chemistry. 63: 7873-84. PMID 26262841 DOI: 10.1021/acs.jafc.5b02830  1
2015 Esposito EX, Hopfinger AJ, Shao CY, Su BH, Chen SZ, Tseng YJ. Exploring possible mechanisms of action for the nanotoxicity and protein binding of decorated nanotubes: interpretation of physicochemical properties from optimal QSAR models. Toxicology and Applied Pharmacology. 288: 52-62. PMID 26200234 DOI: 10.1016/j.taap.2015.07.008  1
2015 Su BH, Tu YS, Lin C, Shao CY, Lin OA, Tseng YJ. Rule-based Prediction Models of Cytochrome P450 Inhibition. Journal of Chemical Information and Modeling. PMID 26108525 DOI: 10.1021/acs.jcim.5b00130  1
2015 Chen HH, Tseng YJ, Wang SY, Tsai YS, Chang CS, Kuo TC, Yao WJ, Shieh CC, Wu CH, Kuo PH. The metabolome profiling and pathway analysis in metabolic healthy and abnormal obesity. International Journal of Obesity (2005). PMID 25907313 DOI: 10.1038/ijo.2015.65  1
2015 Chen GY, Liao HW, Tseng YJ, Tsai IL, Kuo CH. A matrix-induced ion suppression method to normalize concentration in urinary metabolomics studies using flow injection analysis electrospray ionization mass spectrometry. Analytica Chimica Acta. 864: 21-9. PMID 25732423 DOI: 10.1016/j.aca.2015.01.022  1
2015 Su BH, Tu YS, Lin OA, Harn YC, Shen MY, Tseng YJ. Rule-based classification models of molecular autofluorescence. Journal of Chemical Information and Modeling. 55: 434-45. PMID 25625768 DOI: 10.1021/ci5007432  1
2015 Wang SY, Kuo CH, Tseng YJ. Ion trace detection algorithm to extract pure ion chromatograms to improve untargeted peak detection quality for liquid chromatography/time-of-flight mass spectrometry-based metabolomics data. Analytical Chemistry. 87: 3048-55. PMID 25622715 DOI: 10.1021/ac504711d  1
2015 Shao CY, Su BH, Tu YS, Lin C, Lin OA, Tseng YJ. CypRules: a rule-based P450 inhibition prediction server. Bioinformatics (Oxford, England). 31: 1869-71. PMID 25617412 DOI: 10.1093/bioinformatics/btv043  1
2015 Hung CS, Li HY, Kuo CH, Lin MS, Kuo TC, Tsai SJ, Liu PH, Lin CH, Yang CY, Chuang LM, Chen MF, Tseng YJ, Kao HL. Fasting but not changes of plasma metabolome during oral glucose tolerance tests improves the diagnosis of severe coronary arterial stenosis. Clinical Endocrinology. PMID 25557422 DOI: 10.1111/cen.12713  1
2015 Chen GY, Chiu HH, Lin SW, Tseng YJ, Tsai SJ, Kuo CH. Development and application of a comparative fatty acid analysis method to investigate voriconazole-induced hepatotoxicity. Clinica Chimica Acta; International Journal of Clinical Chemistry. 438: 126-34. PMID 25150729 DOI: 10.1016/j.cca.2014.08.013  1
2015 Tzeng TH, Kuo CY, Wang SY, Huang PK, Huang YM, Hsieh WC, Huang YJ, Kuo PH, Yu SA, Lee SC, Tseng YJ, Tian WC, Lu SS. A Portable Micro Gas Chromatography System for Lung Cancer Associated Volatile Organic Compound Detection Ieee Journal of Solid-State Circuits. DOI: 10.1109/JSSC.2015.2489839  1
2015 Tzeng TH, Kuo CY, Wang SY, Huang PK, Kuo PH, Huang YM, Hsieh WC, Yu SA, Tseng YJ, Tian WC, Lee SC, Lu SS. A portable micro gas chromatography system for volatile compounds detection with 15ppb of sensitivity Digest of Technical Papers - Ieee International Solid-State Circuits Conference. 58: 388-389. DOI: 10.1109/ISSCC.2015.7063089  1
2015 Esposito EX, Hopfinger AJ, Shao CY, Su BH, Chen SZ, Tseng YJ. Exploring possible mechanisms of action for the nanotoxicity and protein binding of decorated nanotubes: Interpretation of physicochemical properties from optimal QSAR models Toxicology and Applied Pharmacology. 288: 52-62. DOI: 10.1016/j.taap.2015.07.008  1
2015 Lin MI, Su BH, Lee CH, Wang ST, Wu WC, Dangate P, Wang SY, Huang WI, Cheng TJ, Lin OA, Cheng YSE, Tseng YJ, Sun CM. Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1 European Journal of Medicinal Chemistry. 102: 477-486. DOI: 10.1016/j.ejmech.2015.08.016  1
2014 Lin SW, Kang WY, Lin DT, Lee J, Wu FL, Chen CL, Tseng YJ. Comparison of warfarin therapy clinical outcomes following implementation of an automated mobile phone-based critical laboratory value text alert system. Bmc Medical Genomics. 7: S13. PMID 25079609 DOI: 10.1186/1755-8794-7-S1-S13  1
2013 Tsai IL, Kuo TC, Ho TJ, Harn YC, Wang SY, Fu WM, Kuo CH, Tseng YJ. Metabolomic Dynamic Analysis of Hypoxia in MDA-MB-231 and the Comparison with Inferred Metabolites from Transcriptomics Data. Cancers. 5: 491-510. PMID 24216987 DOI: 10.3390/cancers5020491  1
2013 Su BH, Huang YS, Chang CY, Tu YS, Tseng YJ. Template-based de novo design for type II kinase inhibitors and its extented application to acetylcholinesterase inhibitors. Molecules (Basel, Switzerland). 18: 13487-509. PMID 24184819 DOI: 10.3390/molecules181113487  1
2013 Liu CT, Raghu R, Lin SH, Wang SY, Kuo CH, Tseng YJ, Sheen LY. Metabolomics of ginger essential oil against alcoholic fatty liver in mice. Journal of Agricultural and Food Chemistry. 61: 11231-40. PMID 24171385 DOI: 10.1021/jf403523g  1
2013 Tsai IL, Weng TI, Tseng YJ, Tan HK, Sun HJ, Kuo CH. Screening and confirmation of 62 drugs of abuse and metabolites in urine by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Journal of Analytical Toxicology. 37: 642-51. PMID 24084874 DOI: 10.1093/jat/bkt083  1
2013 Kuo TC, Tian TF, Tseng YJ. 3Omics: a web-based systems biology tool for analysis, integration and visualization of human transcriptomic, proteomic and metabolomic data. Bmc Systems Biology. 7: 64. PMID 23875761 DOI: 10.1186/1752-0509-7-64  1
2013 Huang CC, McDermott MM, Liu K, Kuo CH, Wang SY, Tao H, Tseng YJ. Plasma metabolomic profiles predict near-term death among individuals with lower extremity peripheral arterial disease. Journal of Vascular Surgery. 58: 989-96.e1. PMID 23688629 DOI: 10.1016/j.jvs.2013.04.022  1
2013 Tsai DM, Kang JJ, Lee SS, Wang SY, Tsai IL, Chen GY, Liao HW, Wei-Chu L, Kuo CH, Tseng YJ. Metabolomic analysis of complex chinese remedies: examples of induced nephrotoxicity in the mouse from a series of remedies containing aristolochic Acid. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 263757. PMID 23606874 DOI: 10.1155/2013/263757  1
2013 Tseng YJ, Kuo CT, Wang SY, Liao HW, Chen GY, Ku YL, Shao WC, Kuo CH. Metabolomic characterization of rhubarb species by capillary electrophoresis and ultra-high-pressure liquid chromatography. Electrophoresis. 34: 2918-27. PMID 23580246 DOI: 10.1002/elps.201200580  1
2013 Chang CY, Hsu MT, Esposito EX, Tseng YJ. Oversampling to overcome overfitting: exploring the relationship between data set composition, molecular descriptors, and predictive modeling methods. Journal of Chemical Information and Modeling. 53: 958-71. PMID 23464929 DOI: 10.1021/ci4000536  1
2013 Ho TJ, Kuo CH, Wang SY, Chen GY, Tseng YJ. True ion pick (TIPick): a denoising and peak picking algorithm to extract ion signals from liquid chromatography/mass spectrometry data. Journal of Mass Spectrometry : Jms. 48: 234-42. PMID 23378096 DOI: 10.1002/jms.3154  1
2013 Shao CY, Chen SZ, Su BH, Tseng YJ, Esposito EX, Hopfinger AJ. Dependence of QSAR models on the selection of trial descriptor sets: a demonstration using nanotoxicity endpoints of decorated nanotubes. Journal of Chemical Information and Modeling. 53: 142-58. PMID 23252880 DOI: 10.1021/ci3005308  1
2013 Wang KC, Wang SY, Kuo CH, Tseng YJ. Distribution-based classification method for baseline correction of metabolomic 1D proton nuclear magnetic resonance spectra. Analytical Chemistry. 85: 1231-9. PMID 23249210 DOI: 10.1021/ac303233c  1
2013 Wang SY, Kuo CH, Tseng YJ. Batch Normalizer: a fast total abundance regression calibration method to simultaneously adjust batch and injection order effects in liquid chromatography/time-of-flight mass spectrometry-based metabolomics data and comparison with current calibration methods. Analytical Chemistry. 85: 1037-46. PMID 23240878 DOI: 10.1021/ac302877x  1
2012 Jansen JM, Amaro RE, Cornell W, Tseng YJ, Walters WP. Computational chemistry and drug discovery: a call to action. Future Medicinal Chemistry. 4: 1893-6. PMID 23088271 DOI: 10.4155/fmc.12.137  1
2012 Jansen JM, Cornell W, Tseng YJ, Amaro RE. Teach-Discover-Treat (TDT): collaborative computational drug discovery for neglected diseases. Journal of Molecular Graphics & Modelling. 38: 360-2. PMID 23085175 DOI: 10.1016/j.jmgm.2012.07.007  1
2012 Su BH, Tu YS, Esposito EX, Tseng YJ. Predictive toxicology modeling: protocols for exploring hERG classification and Tetrahymena pyriformis end point predictions. Journal of Chemical Information and Modeling. 52: 1660-73. PMID 22642982 DOI: 10.1021/ci300060b  1
2012 Wang KC, Kuo CH, Tian TF, Tsai MH, Chiung YM, Hsiech CM, Tsai SJ, Wang SY, Tsai DM, Huang CC, Tseng YJ. Metabolomic characterization of laborers exposed to welding fumes. Chemical Research in Toxicology. 25: 676-86. PMID 22292500 DOI: 10.1021/tx200465e  1
2012 Tseng YJ, Hopfinger AJ, Esposito EX. The great descriptor melting pot: mixing descriptors for the common good of QSAR models. Journal of Computer-Aided Molecular Design. 26: 39-43. PMID 22200979 DOI: 10.1007/s10822-011-9511-4  1
2011 Lin FY, Tseng YJ. Structure-based fragment hopping for lead optimization using predocked fragment database. Journal of Chemical Information and Modeling. 51: 1703-15. PMID 21627327 DOI: 10.1021/ci200136j  1
2011 Shen MY, Su BH, Esposito EX, Hopfinger AJ, Tseng YJ. A comprehensive support vector machine binary hERG classification model based on extensive but biased end point hERG data sets. Chemical Research in Toxicology. 24: 934-49. PMID 21504223 DOI: 10.1021/tx200099j  1
2010 Wang SY, Ho TJ, Kuo CH, Tseng YJ. Chromaligner: a web server for chromatogram alignment. Bioinformatics (Oxford, England). 26: 2338-9. PMID 20576623 DOI: 10.1093/bioinformatics/btq337  1
2010 Su BH, Shen MY, Esposito EX, Hopfinger AJ, Tseng YJ. In silico binary classification QSAR models based on 4D-fingerprints and MOE descriptors for prediction of hERG blockage. Journal of Chemical Information and Modeling. 50: 1304-18. PMID 20565102 DOI: 10.1021/ci100081j  1
2010 Kuo CH, Lee CW, Lin SC, Tsai IL, Lee SS, Tseng YJ, Kang JJ, Peng FC, Wei-Chu L. Rapid determination of aristolochic acids I and II in herbal products and biological samples by ultra-high-pressure liquid chromatography-tandem mass spectrometry. Talanta. 80: 1672-80. PMID 20152395 DOI: 10.1016/j.talanta.2009.10.003  1
2008 Zheng T, Hopfinger AJ, Esposito EX, Liu J, Tseng YJ. Membrane-interaction quantitative structure--activity relationship (MI-QSAR) analyses of skin penetration enhancers. Journal of Chemical Information and Modeling. 48: 1238-56. PMID 18507373 DOI: 10.1021/ci8000277  1
2008 Liu J, Kern PS, Gerberick GF, Santos-Filho OA, Esposito EX, Hopfinger AJ, Tseng YJ. Categorical QSAR models for skin sensitization based on local lymph node assay measures and both ground and excited state 4D-fingerprint descriptors. Journal of Computer-Aided Molecular Design. 22: 345-66. PMID 18338230 DOI: 10.1007/s10822-008-9190-y  1
2007 Li Y, Pan D, Liu J, Kern PS, Gerberick GF, Hopfinger AJ, Tseng YJ. Categorical QSAR Models for skin sensitization based upon local lymph node assay classification measures part 2: 4D-fingerprint three-state and two-2-state logistic regression models. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 532-44. PMID 17675333 DOI: 10.1093/toxsci/kfm185  1
2007 Iyer M, Zheng T, Hopfinger AJ, Tseng YJ. QSAR analyses of skin penetration enhancers. Journal of Chemical Information and Modeling. 47: 1130-49. PMID 17472334 DOI: 10.1021/ci700051e  1
2007 Iyer M, Tseng YJ, Senese CL, Liu J, Hopfinger AJ. Prediction and mechanistic interpretation of human oral drug absorption using MI-QSAR analysis. Molecular Pharmaceutics. 4: 218-31. PMID 17397237 DOI: 10.1021/mp0600900  1
2007 Li Y, Tseng YJ, Pan D, Liu J, Kern PS, Gerberick GF, Hopfinger AJ. 4D-fingerprint categorical QSAR models for skin sensitization based on the classification of local lymph node assay measures. Chemical Research in Toxicology. 20: 114-28. PMID 17226934 DOI: 10.1021/tx6002535  1
2004 Senese CL, Duca J, Pan D, Hopfinger AJ, Tseng YJ. 4D-fingerprints, universal QSAR and QSPR descriptors. Journal of Chemical Information and Computer Sciences. 44: 1526-39. PMID 15446810 DOI: 10.1021/ci049898s  1
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