Gustav Edward Lienhard - Publications

Affiliations: 
1972- Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Biochemistry, Cell Biology, Molecular Biology
Website:
https://geiselmed.dartmouth.edu/lienhard/members/

160 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Sano H, Peck GR, Blachon S, Lienhard GE. A potential link between insulin signaling and GLUT4 translocation: Association of Rab10-GTP with the exocyst subunit Exoc6/6b. Biochemical and Biophysical Research Communications. 465: 601-5. PMID 26299925 DOI: 10.1016/j.bbrc.2015.08.069  1
2015 Kettenbach AN, Sano H, Keller SR, Lienhard GE, Gerber SA. SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle. Journal of Proteomics. 114: 48-60. PMID 25463755 DOI: 10.1016/j.jprot.2014.11.001  1
2014 Oeckinghaus A, Postler TS, Rao P, Schmitt H, Schmitt V, Grinberg-Bleyer Y, Kühn LI, Gruber CW, Lienhard GE, Ghosh S. κB-Ras proteins regulate both NF-κB-dependent inflammation and Ral-dependent proliferation Cell Reports. 8: 1793-1807. PMID 25220458 DOI: 10.1016/j.celrep.2014.08.015  1
2011 Sano H, Peck GR, Kettenbach AN, Gerber SA, Lienhard GE. Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C. The Journal of Biological Chemistry. 286: 16541-5. PMID 21454697 DOI: 10.1074/jbc.C111.228908  1
2010 Dash S, Langenberg C, Fawcett KA, Semple RK, Romeo S, Sharp S, Sano H, Lienhard GE, Rochford JJ, Howlett T, Massoud AF, Hindmarsh P, Howell SJ, Wilkinson RJ, Lyssenko V, et al. Analysis of TBC1D4 in patients with severe insulin resistance. Diabetologia. 53: 1239-42. PMID 20349035 DOI: 10.1007/s00125-010-1724-x  1
2009 Peck GR, Chavez JA, Roach WG, Budnik BA, Lane WS, Karlsson HK, Zierath JR, Lienhard GE. Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation. The Journal of Biological Chemistry. 284: 30016-23. PMID 19740738 DOI: 10.1074/jbc.M109.035568  1
2009 Dash S, Sano H, Rochford JJ, Semple RK, Yeo G, Hyden CS, Soos MA, Clark J, Rodin A, Langenberg C, Druet C, Fawcett KA, Tung YC, Wareham NJ, Barroso I, ... Lienhard GE, et al. A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. Proceedings of the National Academy of Sciences of the United States of America. 106: 9350-5. PMID 19470471 DOI: 10.1073/pnas.0900909106  1
2009 Lyons PD, Peck GR, Kettenbach AN, Gerber SA, Roudaia L, Lienhard GE. Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes. Bioscience Reports. 29: 229-35. PMID 19006485 DOI: 10.1042/BSR20080162  1
2008 Lienhard GE. Non-functional phosphorylations? Trends in Biochemical Sciences. 33: 351-2. PMID 18603430 DOI: 10.1016/j.tibs.2008.05.004  1
2008 Chavez JA, Roach WG, Keller SR, Lane WS, Lienhard GE. Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation. The Journal of Biological Chemistry. 283: 9187-95. PMID 18258599 DOI: 10.1074/jbc.M708934200  1
2008 Sano H, Roach WG, Peck GR, Fukuda M, Lienhard GE. Rab10 in insulin-stimulated GLUT4 translocation. The Biochemical Journal. 411: 89-95. PMID 18076383 DOI: 10.1042/BJ20071318  1
2007 Sano H, Eguez L, Teruel MN, Fukuda M, Chuang TD, Chavez JA, Lienhard GE, McGraw TE. Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane. Cell Metabolism. 5: 293-303. PMID 17403373 DOI: 10.1016/j.cmet.2007.03.001  1
2007 Roach WG, Chavez JA, Mîinea CP, Lienhard GE. Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1. The Biochemical Journal. 403: 353-8. PMID 17274760 DOI: 10.1042/BJ20061798  1
2006 Schmelzle K, Kane S, Gridley S, Lienhard GE, White FM. Temporal dynamics of tyrosine phosphorylation in insulin signaling. Diabetes. 55: 2171-9. PMID 16873679 DOI: 10.2337/db06-0148  1
2006 Chavez JA, Gridley S, Sano H, Lane WS, Lienhard GE. The 47kDa Akt substrate associates with phosphodiesterase 3B and regulates its level in adipocytes. Biochemical and Biophysical Research Communications. 342: 1218-22. PMID 16516160 DOI: 10.1016/j.bbrc.2006.02.091  1
2006 Gridley S, Chavez JA, Lane WS, Lienhard GE. Adipocytes contain a novel complex similar to the tuberous sclerosis complex. Cellular Signalling. 18: 1626-32. PMID 16490346 DOI: 10.1016/j.cellsig.2006.01.002  1
2005 Eguez L, Lee A, Chavez JA, Miinea CP, Kane S, Lienhard GE, McGraw TE. Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein. Cell Metabolism. 2: 263-72. PMID 16213228 DOI: 10.1016/j.cmet.2005.09.005  1
2005 Kane S, Lienhard GE. Calmodulin binds to the Rab GTPase activating protein required for insulin-stimulated GLUT4 translocation. Biochemical and Biophysical Research Communications. 335: 175-80. PMID 16055084 DOI: 10.1016/j.bbrc.2005.07.056  1
2005 Mîinea CP, Sano H, Kane S, Sano E, Fukuda M, Peränen J, Lane WS, Lienhard GE. AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain. The Biochemical Journal. 391: 87-93. PMID 15971998 DOI: 10.1042/BJ20050887  1
2005 Karlsson HK, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg-Henriksson H. Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects. Diabetes. 54: 1692-7. PMID 15919790 DOI: 10.2337/diabetes.54.6.1692  1
2005 Sano H, Kane S, Sano E, Lienhard GE. Synip phosphorylation does not regulate insulin-stimulated GLUT4 translocation. Biochemical and Biophysical Research Communications. 332: 880-4. PMID 15913552 DOI: 10.1016/j.bbrc.2005.05.027  1
2005 Bruss MD, Arias EB, Lienhard GE, Cartee GD. Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity. Diabetes. 54: 41-50. PMID 15616009 DOI: 10.2337/diabetes.54.1.41  1
2005 Gridley S, Lane WS, Garner CW, Lienhard GE. Novel insulin-elicited phosphoproteins in adipocytes. Cellular Signalling. 17: 59-66. PMID 15451025 DOI: 10.1016/j.cellsig.2004.05.013  1
2003 Mîinea CP, Lienhard GE. Stoichiometry of site-specific protein phosphorylation estimated with phosphopeptide-specific antibodies. Biotechniques. 34: 828-31. PMID 12703308  1
2003 Sano H, Kane S, Sano E, Mîinea CP, Asara JM, Lane WS, Garner CW, Lienhard GE. Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. The Journal of Biological Chemistry. 278: 14599-602. PMID 12637568 DOI: 10.1074/jbc.C300063200  1
2003 Terauchi Y, Matsui J, Suzuki R, Kubota N, Komeda K, Aizawa S, Eto K, Kimura S, Nagai R, Tobe K, Lienhard GE, Kadowaki T. Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice. The Journal of Biological Chemistry. 278: 14284-90. PMID 12493745 DOI: 10.1074/jbc.M211045200  1
2002 Laustsen PG, Michael MD, Crute BE, Cohen SE, Ueki K, Kulkarni RN, Keller SR, Lienhard GE, Kahn CR. Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice. Genes & Development. 16: 3213-22. PMID 12502742 DOI: 10.1101/gad.1034802  1
2002 Björnholm M, He AR, Attersand A, Lake S, Liu SC, Lienhard GE, Taylor S, Arner P, Zierath JR. Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans. Diabetologia. 45: 1697-702. PMID 12488959 DOI: 10.1007/s00125-002-0945-z  1
2002 Kane S, Sano H, Liu SC, Asara JM, Lane WS, Garner CC, Lienhard GE. A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. The Journal of Biological Chemistry. 277: 22115-8. PMID 11994271 DOI: 10.1074/jbc.C200198200  1
2002 Sano H, Liu SC, Lane WS, Piletz JE, Lienhard GE. Insulin receptor substrate 4 associates with the protein IRAS. The Journal of Biological Chemistry. 277: 19439-47. PMID 11912194 DOI: 10.1074/jbc.M111838200  1
2001 Laustsen PG, Lane WS, Bennett V, Lienhard GE. Association of protein kinase Cλ with adducin in 3T3-L1 adipocytes Biochimica Et Biophysica Acta - Molecular Cell Research. 1539: 163-172. PMID 11389978 DOI: 10.1016/S0167-4889(01)00105-7  1
2000 Liu SCH, Lane WS, Lienhard GE. Cloning and preliminary characterization of a 105 kDa protein with an N-terminal kinase-like domain Biochimica Et Biophysica Acta - Gene Structure and Expression. 1517: 148-152. PMID 11118629 DOI: 10.1016/S0167-4781(00)00234-7  1
2000 Fantin VR, Wang Q, Lienhard GE, Keller SR. Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis. American Journal of Physiology. Endocrinology and Metabolism. 278: E127-33. PMID 10644546  1
1999 Fantin VR, Keller SR, Lienhard GE, Wang LM. Insulin receptor substrate 4 supports insulin- and interleukin 4-stimulated proliferation of hematopoietic cells. Biochemical and Biophysical Research Communications. 260: 718-23. PMID 10403832 DOI: 10.1006/bbrc.1999.0967  1
1999 Liu SC, Wang Q, Lienhard GE, Keller SR. Insulin receptor substrate 3 is not essential for growth or glucose homeostasis. The Journal of Biological Chemistry. 274: 18093-9. PMID 10364263 DOI: 10.1074/jbc.274.25.18093  1
1999 Morris NJ, Ross SA, Neveu JM, Lane WS, Lienhard GE. Cloning and preliminary characterization of a 121 kDa protein with multiple predicted C2 domains Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1431: 525-530. PMID 10350628 DOI: 10.1016/S0167-4838(99)00068-0  1
1999 Morris NJ, Ross SA, Neveu JM, Lane WS, Lienhard GE. Cloning and characterization of a 22 kDa protein from rat adipocytes: A new member of the reticulon family Biochimica Et Biophysica Acta - Molecular Cell Research. 1450: 68-76. PMID 10231557 DOI: 10.1016/S0167-4889(99)00033-6  1
1999 Fantin VR, Lavan BE, Wang Q, Jenkins NA, Gilbert DJ, Copeland NG, Keller SR, Lienhard GE. Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene. Endocrinology. 140: 1329-37. PMID 10067860 DOI: 10.1210/endo.140.3.6578  1
1998 Ross SA, Lienhard GE, Lavan BE. Association of insulin receptor substrate 3 with SH2 domain-containing proteins in rat adipocytes. Biochemical and Biophysical Research Communications. 247: 487-92. PMID 9642156 DOI: 10.1006/bbrc.1998.8821  1
1998 Fantin VR, Sparling JD, Slot JW, Keller SR, Lienhard GE, Lavan BE. Characterization of insulin receptor substrate 4 in human embryonic kidney 293 cells. The Journal of Biological Chemistry. 273: 10726-32. PMID 9553137 DOI: 10.1074/jbc.273.17.10726  1
1998 Ross SA, Keller SR, Lienhard GE. Increased intracellular sequestration of the insulin-regulated aminopeptidase upon differentiation of 3T3-L1 cells. The Biochemical Journal. 330: 1003-8. PMID 9480922  1
1998 Morris NJ, Ross SA, Lane WS, Moestrup SK, Petersen CM, Keller SR, Lienhard GE. Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes. The Journal of Biological Chemistry. 273: 3582-7. PMID 9452485 DOI: 10.1074/jbc.273.6.3582  1
1997 Ross SA, Herbst JJ, Keller SR, Lienhard GE. Trafficking kinetics of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications. 239: 247-51. PMID 9345303 DOI: 10.1006/bbrc.1997.7459  1
1997 Lavan BE, Fantin VR, Chang ET, Lane WS, Keller SR, Lienhard GE. A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family. The Journal of Biological Chemistry. 272: 21403-7. PMID 9261155 DOI: 10.1074/jbc.272.34.21403  1
1997 Herbst JJ, Ross SA, Scott HM, Bobin SA, Morris NJ, Lienhard GE, Keller SR. Insulin stimulates cell surface aminopeptidase activity toward vasopressin in adipocytes. The American Journal of Physiology. 272: E600-6. PMID 9142880  1
1997 Lavan BE, Lane WS, Lienhard GE. The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family. The Journal of Biological Chemistry. 272: 11439-43. PMID 9111055 DOI: 10.1074/jbc.272.17.11439  1
1997 Morris NJ, Ducret A, Aebersold R, Ross SA, Keller SR, Lienhard GE. Membrane amine oxidase cloning and identification as a major protein in the adipocyte plasma membrane. The Journal of Biological Chemistry. 272: 9388-92. PMID 9083076 DOI: 10.1074/jbc.272.14.9388  1
1996 Ross SA, Scott HM, Morris NJ, Leung WY, Mao F, Lienhard GE, Keller SR. Characterization of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 271: 3328-32. PMID 8621739  1
1995 D'Ambrosio C, Keller SR, Morrione A, Lienhard GE, Baserga R, Surmacz E. Transforming potential of the insulin receptor substrate 1. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 6: 557-62. PMID 7647039  1
1995 Herbst JJ, Andrews GC, Contillo LG, Singleton DH, Genereux PE, Gibbs EM, Lienhard GE. Effect of the activation of phosphatidylinositol 3-kinase by a thiophosphotyrosine peptide on glucose transport in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 270: 26000-5. PMID 7592791 DOI: 10.1074/jbc.270.43.26000  1
1995 Keller SR, Scott HM, Mastick CC, Aebersold R, Lienhard GE. Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles. The Journal of Biological Chemistry. 270: 23612-8. PMID 7559527 DOI: 10.1074/jbc.270.40.23612  1
1995 Yin T, Keller SR, Quelle FW, Witthuhn BA, Tsang ML, Lienhard GE, Ihle JN, Yang YC. Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases. The Journal of Biological Chemistry. 270: 20497-502. PMID 7544789 DOI: 10.1074/jbc.270.35.20497  1
1995 Kuhne MR, Zhao ZH, Lienhard GE. Evidence Against Dephosphorylation of Insulin-Elicited Phosphotyrosine Proteins in Vivo by the Phosphatase PTP2C Biochemical and Biophysical Research Communications. 211: 190-197. PMID 7540003 DOI: 10.1006/bbrc.1995.1795  1
1994 Keller SR, Lienhard GE. Insulin signalling: the role of insulin receptor substrate 1. Trends in Cell Biology. 4: 115-9. PMID 14731733 DOI: 10.1016/0962-8924(94)90065-5  1
1994 Mastick CC, Aebersold R, Lienhard GE. Characterization of a Major Protein in GLUT4 Vesicles: Concentration in the vesicles and insulin-stimulated translocation to the plasma membrane Journal of Biological Chemistry. 269: 6089-6092. PMID 8119954  1
1994 Lienhard GE. Life without the IRS Nature. 372: 128-129. PMID 7969441  1
1994 Lavan BE, Lienhard GE. Insulin signalling and the stimulation of glucose transport. Biochemical Society Transactions. 22: 676-80. PMID 7821662  1
1994 Kuhné MR, Zhao Z, Rowles J, Lavan BE, Shen SH, Fischer EH, Lienhard GE. Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C. The Journal of Biological Chemistry. 269: 15833-7. PMID 7515062  1
1994 Lamphere L, Carpenter CL, Sheng ZF, Kallen RG, Lienhard GE. Activation of PI 3-kinase in 3T3-L1 adipocytes by association with insulin receptor substrate-1 American Journal of Physiology - Endocrinology and Metabolism. 266. PMID 7513124  1
1994 Herbst JJ, Andrews G, Contillo L, Lamphere L, Gardner J, Lienhard GE, Gibbs EM. Potent activation of phosphatidylinositol 3′-kinase by simple phosphotyrosine peptides derived from insulin receptor substrate 1 containing two YMXM motifs for binding SH2 domains Biochemistry. 33: 9376-9381.  1
1993 Kuhné MR, Pawson T, Lienhard GE, Feng GS. The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp Journal of Biological Chemistry. 268: 11479-11481. PMID 8505282  1
1993 Stoffel M, Espinosa R, Keller SR, Lienhard GE, Le Beau MM, Bell GI. Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism. Diabetologia. 36: 335-7. PMID 8477879 DOI: 10.1007/BF00400237  1
1993 Keller SR, Aebersold R, Garner CW, Lienhard GE. The insulin-elicited 160 kDa phosphotyrosine protein in mouse adipocytes is an insulin receptor substrate 1: identification by cloning. Biochimica Et Biophysica Acta. 1172: 323-6. PMID 8448209 DOI: 10.1016/0167-4781(93)90222-Y  1
1993 Keller SR, Lamphere L, Lavan BE, Kuhné MR, Lienhard GE. Insulin and IGF-I signaling through the insulin receptor substrate 1. Molecular Reproduction and Development. 35: 346-51; discussion 3. PMID 8398112 DOI: 10.1002/mrd.1080350405  1
1993 Laurie SM, Cain CC, Lienhard GE, Castle JD. The glucose transporter GluT4 and secretory carrier membrane proteins (SCAMPs) colocalize in rat adipocytes and partially segregate during insulin stimulation. The Journal of Biological Chemistry. 268: 19110-7. PMID 8360193  1
1993 Wang LM, Keegan AD, Li W, Lienhard GE, Pacini S, Gutkind JS, Myers MG, Sun XJ, White MF, Aaronson SA, Paul WE, Pierce JH. Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells Proceedings of the National Academy of Sciences of the United States of America. 90: 4032-4036. PMID 7683417  1
1993 Lavan BE, Lienhard GE. The insulin-elicited 60-kDa phosphotyrosine protein in rat adipocytes is associated with phosphatidylinositol 3-kinase. The Journal of Biological Chemistry. 268: 5921-8. PMID 7680652  1
1992 Lienhard GE, Slot JW, James DE, Mueckler MM. How cells absorb glucose Scientific American. 266: 86-91. PMID 1734513  1
1992 Cain CC, Trimble WS, Lienhard GE. Members of the VAMP family of synaptic vesicle proteins are components of glucose transporter-containing vesicles from rat adipocytes Journal of Biological Chemistry. 267: 11681-11684. PMID 1601842  1
1992 Lamphere L, Lienhard GE. Components of signaling pathways for insulin and insulin-like growth factor-I in muscle myoblasts and myotubes Endocrinology. 131: 2196-2202. PMID 1385098 DOI: 10.1210/en.131.5.2196  1
1992 Lavan BE, Kuhné MR, Garner CW, Anderson D, Reedijk M, Pawson T, Lienhard GE. The association of insulin-elicited phosphotyrosine proteins with src homology 2 domains. The Journal of Biological Chemistry. 267: 11631-6. PMID 1375946  1
1992 Rice KM, Lienhard GE, Garner CW. Regulation of the expression of pp160, a putative insulin receptor signal protein, by insulin, dexamethasone, and 1-methyl-3-isobutylxanthine in 3T3-L1 adipocytes Journal of Biological Chemistry. 267: 10163-10167. PMID 1374400  1
1991 Slot JW, Geuze HJ, Gigengack S, Lienhard GE, James DE. Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat Journal of Cell Biology. 113: 123-135. PMID 2007617  1
1991 Slot JW, Geuze HJ, Gigengack S, James DE, Lienhard GE. Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat Proceedings of the National Academy of Sciences of the United States of America. 88: 7815-7819. PMID 1881917  1
1991 Keller SR, Kitagawa K, Aebersold R, Lienhard GE, Garner CW. Isolation and characterization of the 160,000-Da phosphotyrosyl protein, a putative participant in insulin signaling. The Journal of Biological Chemistry. 266: 12817-20. PMID 1712770  1
1990 Calderhead DM, Kitagawa K, Lienhard GE, Gould GW. Translocation of the brain-type glucose transporter largely accounts for insulin stimulation of glucose transport in BC3H-1 myocytes Biochemical Journal. 269: 597-601. PMID 2202294  1
1990 Calderhead DM, Kitagawa K, Tanner LI, Holman GD, Lienhard GE. Insulin regulation of the two glucose transporters in 3T3-L1 adipocytes Journal of Biological Chemistry. 265: 13800-13808. PMID 2199443  1
1990 Davies A, Ciardelli TL, Lienhard GE, Boyle JM, Whetton AD, Baldwin SA. Site-specific antibodies as probes of the topology and function of the human erythrocyte glucose transporter. The Biochemical Journal. 266: 799-808. PMID 1691633  1
1989 Gould GW, Lienhard GE. Expression of a functional glucose transporter in Xenopus oocytes Biochemistry. 28: 9447-9452. PMID 2692709 DOI: 10.1021/bi00450a030  1
1989 Kitagawa K, Rosen BS, Spiegelman BM, Lienhard GE, Tanner LI. Insulin stimulates the acute release of adipsin from 3T3-L1 adipocytes Bba - Molecular Cell Research. 1014: 83-89. PMID 2679882 DOI: 10.1016/0167-4889(89)90244-9  1
1989 Gould GW, Lienhard GE, Tanner LI, Gibbs EM. Phenylarsine oxide stimulates hexose transport in 3T3-L1 adipocytes by a mechanism other than an increase in surface transporters. Archives of Biochemistry and Biophysics. 268: 264-75. PMID 2643384 DOI: 10.1016/0003-9861(89)90588-2  1
1989 Baldwin SA, Lienhard GE. Purification and reconstitution of glucose transporter from human erythrocytes Methods in Enzymology. 174: 39-50. PMID 2633031  1
1989 Appleman JR, Lienhard GE. Kinetics of the purified glucose transporter. direct measurement of the rates of interconversion of transporter conformers Biochemistry. 28: 8221-8227. PMID 2605179  1
1989 Tanner LI, Lienhard GE. Localization of transferrin receptors and insulin-like growth factor II receptors in vesicles from 3T3-L1 adipocytes that contain intracellular glucose transporters Journal of Cell Biology. 108: 1537-1545. PMID 2538483  1
1989 Gould GW, Derechin V, James DE, Tordjman K, Ahern S, Gibbs EM, Lienhard GE, Mueckler M. Insulin-stimulated translocation of the HepG2/erythrocyte-type glucose transporter expressed in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 264: 2180-4. PMID 2536700  1
1989 Lienhard GE. Insuline may cause translocation of proteins to the cell surface by stimulating membrane trafficking from the trans Golgi reticulum Genes and Gene Products in the Development of Diabetes Mellitus: Proceedings of the 3rd Nordisk Insulin Symposium 'Genes Ane Gene Products in the Development of Diabetes Mellitus'. Ics866. 313-328.  1
1988 Blok J, Gibbs EM, Lienhard GE, Slot JW, Geuze HJ. Insulin-induced translocation of glucose transporters from post-Golgi compartments to the plasma membrane of 3T3-L1 adipocytes. The Journal of Cell Biology. 106: 69-76. PMID 3276714  1
1988 Calderhead DM, Lienhard GE. Labeling of glucose transporters at the cell surface in 3T3-L1 adipocytes. Evidence for both translocation and a second mechanism in the insulin stimulation of transport Journal of Biological Chemistry. 263: 12171-12174. PMID 3137219  1
1988 Froehner SC, Davies A, Baldwin SA, Lienhard GE. The blood-nerve barrier is rich in glucose transporter. Journal of Neurocytology. 17: 173-8. PMID 3060567 DOI: 10.1007/BF01674204  1
1988 Gibbs EM, Lienhard GE, Gould GW. Insulin-induced translocation of glucose transporters to the plasma membrane precedes full stimulation of hexose transport. Biochemistry. 27: 6681-5. PMID 3058203  1
1988 Brown SJ, Gould GW, Davies A, Baldwin SA, Lienhard GE, Gibbs EM. Characterization of vesicles containing insulin-responsive intracellular glucose transporters isolated from 3T3-L1 adipocytes by an improved procedure. Biochimica Et Biophysica Acta. 971: 339-50. PMID 3048418 DOI: 10.1016/0167-4889(88)90150-4  1
1988 Schulz M, Lienhard G, Rupp F, Zinkernagel RM, Hengartner H. Expression of T cell receptor gamma-chain in murine cytotoxic T cells: analysis of a highly transcribed nonrearranged gene cluster. Experimental Cell Biology. 56: 181-9. PMID 2849571  1
1988 Witters LA, Watts TD, Gould GW, Lienhard GE, Gibbs EM. Regulation of protein phosphorylation by insulin and an insulinomimetic oligosaccharide in 3T3-L1 adipocytes and Fao hepatoma cells. Biochemical and Biophysical Research Communications. 153: 992-8. PMID 2839176 DOI: 10.1016/S0006-291X(88)81326-3  1
1987 Allard WJ, Gibbs EM, Witters LA, Lienhard GE. The glucose transporter in human fibroblasts is phosphorylated in response to phorbol ester but not in response to growth factors. Biochimica Et Biophysica Acta. 929: 288-95. PMID 3300786 DOI: 10.1016/0167-4889(87)90255-2  1
1987 Tanner LI, Lienhard GE. Insulin elicits a redistribution of transferrin receptors in 3T3-L1 adipocytes through an increase in the rate constant for receptor externalization Journal of Biological Chemistry. 262: 8975-8980. PMID 3298247  1
1987 Horner HC, Munck A, Lienhard GE. Dexamethasone causes translocation of glucose transporters from the plasma membrane to an intracellular site in human fibroblasts. The Journal of Biological Chemistry. 262: 17696-702. PMID 2826429  1
1986 Gibbs EM, Allard WJ, Lienhard GE. The glucose transporter in 3T3-L1 adipocytes is phosphorylated in response to phorbol ester but not in response to insulin. The Journal of Biological Chemistry. 261: 16597-603. PMID 3536929  1
1986 Biber JW, Lienhard GE. Isolation of vesicles containing insulin-responsive, intracellular glucose transporters from 3T3-L1 adipocytes Journal of Biological Chemistry. 261: 16180-16184. PMID 3536924  1
1986 Gibbs EM, Lienhard GE, Appleman JR, Lane MD, Frost SC. Insulin stimulates fluid-phase endocytosis and exocytosis in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 261: 3944-51. PMID 3512562  1
1986 Schroer DW, Frost SC, Kohanski RA, Lane MD, Lienhard GE. Identification and partial purification of the insulin-responsive glucose transporter from 3T3-L1 adipocytes. Biochimica Et Biophysica Acta. 885: 317-26. PMID 3511974 DOI: 10.1016/0167-4889(86)90247-8  1
1985 Appleman JR, Lienhard GE. Rapid kinetics of the glucose transporter from human erythrocytes. Detection and measurement of a half-turnover of the purified transporter Journal of Biological Chemistry. 260: 4575-4578. PMID 4039316  1
1985 Mueckler M, Caruso C, Baldwin SA, Panico M, Blench I, Morris HR, Allard WJ, Lienhard GE, Lodish HF. Sequence and structure of a human glucose transporter Science. 229: 941-945. PMID 3839598 DOI: 10.1126/science.3839598  1
1985 Witters LA, Vater CA, Lienhard GE. Phosphorylation of the glucose transporter in vitro and in vivo by protein kinase C Nature. 315: 777-778. PMID 3159967 DOI: 10.1038/315777a0  1
1985 Allard WJ, Lienhard GE. Monoclonal antibodies to the glucose transporter from human erythrocytes. Identification of the transporter as a M(r) = 55,000 protein Journal of Biological Chemistry. 260: 8668-8675. PMID 2410404  1
1985 Allard WJ, Lienhard GE. Monoclonal antibodies to the human erythrocyte glucose transporter. Unambiguous identification of the transporter as a 46,000 dalton polypeptide Federation Proceedings. 44.  1
1985 Appleman JR, Lienhard GE. Rapid kinetics of the glucose transporter from human erythrocytes: Detection and measurement of a half-turnover of the purified transporter Federation Proceedings. 44.  1
1985 Frost S, Lane MD, Lienhard G, Gibbs M. Insulin-activated fluid-phase endocytosis in 3T3-L1 adipocytes Federation Proceedings. 44: 6119.  1
1985 Gibbs EM, Lienhard GE, Lane MD, Frost SC. Kinetics of fluid-phase exocytosis in 3T3-L1 adipocytes: Stimulation by insulin Federation Proceedings. 44: No. 8147.  1
1984 Lienhard GE, Crabb JH, Ransome KJ. Endoglycosidase F cleaves the oligosaccharides from the glucose transporter of the human erythrocyte Bba - Biomembranes. 769: 404-410. PMID 6421318 DOI: 10.1016/0005-2736(84)90324-9  1
1984 Gibbs EM, Lienhard GE. Fluid-phase endocytosis by isolated rat adipocytes. Journal of Cellular Physiology. 121: 569-75. PMID 6389574 DOI: 10.1002/jcp.1041210316  1
1984 Gorga JC, Lienhard GE. One transporter per vesicle: Determination of the basis of the insulin effect on glucose transport Federation Proceedings. 43: 2237-2241. PMID 6370726  1
1983 Klip A, Walker D, Ransome KJ, Schroer DW, Lienhard GE. Identification of the glucose transporter in rat skeletal muscle Archives of Biochemistry and Biophysics. 226: 198-205. PMID 6685458 DOI: 10.1016/0003-9861(83)90285-0  1
1983 Lienhard GE. Regulation of cellular membrane transport by the exocytotic insertion and endocytic retrieval of transporters Trends in Biochemical Sciences. 8: 125-127. DOI: 10.1016/0968-0004(83)90234-7  1
1982 Gorga FR, Lienhard GE. Changes in the intrinsic fluorescence of the human erythrocyte monosaccharide transporter upon ligand binding Biochemistry. 21: 1905-1908. PMID 7200802  1
1982 Lienhard GE, Kim HH, Ransome KJ, Gorga JC. Immunological identification of an insulin-responsive glucose transporter Biochemical and Biophysical Research Communications. 105: 1150-1156. PMID 7046752 DOI: 10.1016/0006-291X(82)91090-7  1
1982 Baldwin SA, Baldwin JM, Lienhard GE. Monosaccharide transporter of the human erythrocyte. Characterization of an improved preparation. Biochemistry. 21: 3836-42. PMID 6890381  1
1982 Shanahan MF, Olson SA, Weber MJ, Lienhard GE, Gorga JC. Photolabeling of glucose-sensitive cytochalasin B binding proteins in erythrocyte, fibroblast and adipocyte membranes Biochemical and Biophysical Research Communications. 107: 38-43. PMID 6289825 DOI: 10.1016/0006-291X(82)91666-7  1
1982 Salter DW, Baldwin SA, Lienhard GE, Weber MJ. Proteins antigenically related to the human erythrocyte glucose transporter in normal and Rous sarcoma virus-transformed chicken embryo fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 79: 1540-1544. PMID 6280190  1
1982 Gorga JC, Lienhard GE. Insulin stimulation of glucose transport in adipocytes Federation Proceedings. 41.  1
1981 Gorga FR, Lienhard GE. Equilibria and kinetics of ligand binding to the human erythrocyte glucose transporter. Evidence for an alternating conformation model for transport Biochemistry. 20: 5108-5113. PMID 7295669  1
1981 Baldwin JM, Gorga JC, Lienhard GE. The monosaccharide transporter of the human erythrocyte. Transport activity upon reconstitution. The Journal of Biological Chemistry. 256: 3685-9. PMID 7194337  1
1981 Baldwin SA, Lienhard GE. Glucose transport across plasma membranes: facilitated diffusion systems Trends in Biochemical Sciences. 6: 208-211. DOI: 10.1016/0968-0004(81)90076-1  1
1981 Matteson DS, Sadhu KM, Lienhard GE. (R)-1-acetamido-2-phenylethaneboronic acid. A specific transition-state analogue for chymotrypsin Journal of the American Chemical Society. 103: 5241-5242.  1
1980 Baldwin JM, Lienhard GE, Baldwin SA. The monosaccharide transport system of the human erythrocyte. Orientation upon reconstitution. Biochimica Et Biophysica Acta. 599: 699-714. PMID 7407110  1
1980 Baldwin SA, Lienhard GE. Immunological identification of the human erythrocyte monosaccharide transporter Biochemical and Biophysical Research Communications. 94: 1401-1408. PMID 6156682 DOI: 10.1016/0006-291X(80)90575-6  1
1979 Baldwin SA, Baldwin JM, Gorga FR, Lienhard GE. Purification of the cytochalasin B binding component of the human erythrocyte monosaccharide transport system. Biochimica Et Biophysica Acta. 552: 183-8. PMID 435493 DOI: 10.1016/0005-2736(79)90257-8  1
1979 Gorga FR, Baldwin SA, Lienhard GE. The monosaccharide transporter from human erythrocytes is heterogeneously glycosylated Biochemical and Biophysical Research Communications. 91: 955-961. PMID 118753 DOI: 10.1016/0006-291X(79)91972-7  1
1978 Zoccoli MA, Baldwin SA, Lienhard GE. The monosaccharide transport system of the human erythrocyte. Solubilization and characterization on the basis of cytochalasin B binding Journal of Biological Chemistry. 253: 6923-6930. PMID 690133  1
1977 Zoccoli MA, Lienhard GE. The activity of the erythrocyte monosaccharide transport system is not correlated with crosslinkage of band 3 protein Biochemical and Biophysical Research Communications. 76: 446-452. PMID 1027439 DOI: 10.1016/0006-291X(77)90745-8  1
1977 Lienhard GE, Gorga FR, Orasky JE, Zoccoli MA. Monosaccharide transport system of the human erythrocyte. Identification of the cytochalasin B binding component Biochemistry. 16: 4921-4926. PMID 911802  1
1977 Zoccoli MA, Lienhard GE. Monosaccharide transport in protein depleted vesicles from erythrocyte membranes Journal of Biological Chemistry. 252: 3131-3135. PMID 863876  1
1977 Wardzala LJ, Cushman SW, Lienhard GE. Characterization of cytochalasin B binding to adipose cell ghosts and plasma membranes Federation Proceedings. 36.  1
1976 Lienhard GE, Wardzala LJ. Cytochalasin B reacts with thiols Febs Letters. 64: 69-72. PMID 1269765 DOI: 10.1016/0014-5793(76)80251-7  1
1976 Gutowski JA, Lienhard GE. Transition state analogs for thiamin pyrophosphate dependent enzymes Journal of Biological Chemistry. 251: 2863-2866. PMID 770474  1
1974 Secemski II, Lienhard GE. The effect of gadolinium ion on the binding of inhibitors and substrates to lysozyme Journal of Biological Chemistry. 249: 2932-2938. PMID 4857195  1
1974 David Rawn J, Lienhard GE. The inactivation of acetylcholinesterase by trimethyloxonium ion, an active-site-directed methylating agent Biochemical and Biophysical Research Communications. 56: 654-660. PMID 4826873 DOI: 10.1016/0006-291X(74)90655-X  1
1974 Rawn JD, Lienhard GE. The binding of boronic acids to chymotrypsin Biochemistry. 13: 3124-3130.  1
1974 Rawn JD, Patrick J, Lienhard GE. Decamethoxonium, an alkylating analog of decamethonium [24] Journal of the American Chemical Society. 96: 7585-7586.  1
1973 Lindquist RN, Lynn JL, Lienhard GE. Possible transition-state analogs for ribonuclease. The complexes of uridine with oxovanadium(IV) ion and vanadium(V) ion Journal of the American Chemical Society. 95: 8762-8768. PMID 4783413  1
1973 Lienhard GE, Secemski II. P 1 ,P 5 -Di(adenosine-5')pentaphosphate, a potent multisubstrate inhibitor of adenylate kinase Journal of Biological Chemistry. 248: 1121-1123. PMID 4734335  1
1973 Lienhard GE. Enzymatic catalysis and transition-state theory Science. 180: 149-154. PMID 4632837  1
1973 Lienhard GE, Secemski II. The use of gadolinium ion to determine the mode(s) of binding of substrates and inhibitors to lysozyme Federation Proceedings. 32: 1833.  1
1972 Secemski II, Lehrer SS, Lienhard GE. A transition state analog for lysozyme Journal of Biological Chemistry. 247: 4740-4748. PMID 5052219  1
1972 Lienhard GE, Secemski II, Koehler KA, Lindquist RN. Enzymatic catalysis and the transition state theory of reaction rates: transition state analogs Cold Spring Harbor Symposia On Quantitative Biology. 36: 45-51. PMID 4508159  1
1972 Lienhard GE. Chapter 23. Transition State Analogs as Enzyme Inhibitors Annual Reports in Medicinal Chemistry. 7: 249-258. DOI: 10.1016/S0065-7743(08)60818-0  1
1972 Koehler KA, Jackson RC, Lienhard GE. A search for the addition of monodentate nucleophiles to boric and benzeneboronic acids in water Journal of Organic Chemistry. 37: 2232-2237.  1
1971 Secemski II, Lienhard GE. The role of strain in catalysis by lysozyme [18] Journal of the American Chemical Society. 93: 3549-3550. PMID 5560476  1
1971 Koehler KA, Lienhard GE. 2-Phenylethaneboronic acid, a possible transition-state analog for chymotrypsin Biochemistry. 10: 2477-2483. PMID 5557796  1
1970 Lienhard GE. Kinetic evidence for a (4-amino-2-methyl-5-pyrimidinyl)methyl-enzyme intermediate in the thiaminase I reaction Biochemistry. 9: 3011-3020. PMID 5474802  1
1970 Crosby J, Lienhard GE. Mechanisms of thiamine-catalyzed reactions. A kinetic analysis of the decarboxylation of pyruvate by 3,4-dimethylthiazolium ion in water and ethanol Journal of the American Chemical Society. 92: 5707-5716. PMID 5458742  1
1970 Crosby J, Stone R, Lienhard GE. Mechanisms of thiamine-catalyzed reactions. Decarboxylation of 2-(1-carboxy-1-hydroxyethyl)-3,4-dimethylthiazolium chloride Journal of the American Chemical Society. 92: 2891-2900. PMID 5439974  1
1969 Lienhard GE, Wang TC. On the mechanism of acid-catalyzed enolization of ketones Journal of the American Chemical Society. 91: 1146-1153.  1
1968 Lienhard GE, Wang TC. Kinetics of proton transfer from the α carbon of ethyl thioacetate and its dimethyliminium derivative Journal of the American Chemical Society. 90: 3781-3787.  1
1967 Lienhard GE, Anderson FH. General acid and general base catalysis by the monoanions of dicarboxylic acids Journal of Organic Chemistry. 32: 2229-2233.  1
1966 Lienhard GE, Jencks WP. Thiol addition to the carbonyl group. Equilibria and kinetics. Journal of the American Chemical Society. 88: 3982-94. PMID 5915153  1
1966 Lienhard GE. Kinetics and mechanism of the hydrolysis of 2-acetyl-3,4-dimethylthiazolium ion Journal of the American Chemical Society. 88: 5642-5649.  1
1965 Lienhard GE, Jencks WP. The reaction of carbanions with N,S-diacetylcysteamine. A model for enzymatic carbon--carbon condensation. Journal of the American Chemical Society. 87: 3863-74. PMID 5845265  1
1965 Lienhard GE, Jencks WP. Kinetic demonstration of a tetrahedral intermediate in the hydrolysis of diethyl acetylmalonate and diethyl acetylethylmalonate Journal of the American Chemical Society. 87: 3855-3862.  1
1964 Lienhard GE, Rose IA. The mechanism of action of 6-phosphogluconate dehydrogenase Biochemistry. 3: 190-195. PMID 14163940  1
1964 Lienhard GE, Rose IA. The stereochemistry of decarboxylation of isocitrate by isocitric acid dehydrogenase Biochemistry. 3: 185-190. PMID 14163939  1
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