George M. Church - Publications

Genetics Harvard Medical School, Boston, MA, United States 
Computational Genetics

366 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nguyen HQ, Chattoraj S, Castillo D, Nguyen SC, Nir G, Lioutas A, Hershberg EA, Martins NMC, Reginato PL, Hannan M, Beliveau BJ, Church GM, Daugharthy ER, Marti-Renom MA, Wu CT. 3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing. Nature Methods. PMID 32719531 DOI: 10.1038/s41592-020-0890-0  0.76
2020 Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, D'Gama AM, Kim SN, Hill RS, Goldberg AP, Poultney C, Minshew NJ, Kushima I, Aleksic B, Ozaki N, ... ... Church GM, et al. Publisher Correction: Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nature Neuroscience. PMID 32665711 DOI: 10.1038/s41593-020-0681-z  0.36
2020 Kuru E, Määttälä RM, Noguera K, Stork DA, Narasimhan K, Rittichier J, Wiegand D, Church GM. Release Factor Inhibiting Antimicrobial Peptides Improve Nonstandard Amino Acid Incorporation in Wild-type Bacterial Cells. Acs Chemical Biology. PMID 32603088 DOI: 10.1021/acschembio.0c00055  0.56
2020 Eroshenko N, Gill T, Keaveney MK, Church GM, Trevejo JM, Rajaniemi H. Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures. Nature Biotechnology. PMID 32504046 DOI: 10.1038/s41587-020-0577-1  0.68
2020 Wannier TM, Nyerges A, Kuchwara HM, Czikkely M, Balogh D, Filsinger GT, Borders NC, Gregg CJ, Lajoie MJ, Rios X, Pál C, Church GM. Improved bacterial recombineering by parallelized protein discovery. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467157 DOI: 10.1073/pnas.2001588117  1
2020 Turczyk BM, Busby M, Martin AL, Daugharthy ER, Myung D, Terry RC, Inverso SA, Kohman RE, Church GM. Spatial Sequencing: A Perspective. Journal of Biomolecular Techniques : Jbt. PMID 32382252 DOI: 10.7171/jbt.20-3102-003  0.8
2020 Smith CJ, Castanon O, Said K, Volf V, Khoshakhlagh P, Hornick A, Ferreira R, Wu CT, Güell M, Garg S, Ng AHM, Myllykallio H, Church GM. Enabling large-scale genome editing at repetitive elements by reducing DNA nicking. Nucleic Acids Research. PMID 32315033 DOI: 10.1093/nar/gkaa239  0.76
2020 Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, ... Church GM, et al. A Deep Learning Approach to Antibiotic Discovery. Cell. 181: 475-483. PMID 32302574 DOI: 10.1016/j.cell.2020.04.001  0.96
2020 Niu D, Ma X, Yuan T, Niu Y, Xu Y, Sun Z, Ping Y, Li W, Zhang J, Wang T, Church GM. Porcine genome engineering for xenotransplantation. Advanced Drug Delivery Reviews. PMID 32275950 DOI: 10.1016/j.addr.2020.04.001  0.76
2020 Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackerman Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, ... Church GM, et al. A Deep Learning Approach to Antibiotic Discovery. Cell. 180: 688-702.e13. PMID 32084340 DOI: 10.1016/j.cell.2020.01.021  0.96
2019 Minev D, Guerra R, Kishi JY, Smith C, Krieg E, Said K, Hornick A, Sasaki HM, Filsinger G, Beliveau BJ, Yin P, Church GM, Shih WM. Rapid in vitro production of single-stranded DNA. Nucleic Acids Research. PMID 31713635 DOI: 10.1093/nar/gkz998  0.76
2019 Ostrov N, Beal J, Ellis T, Gordon DB, Karas BJ, Lee HH, Lenaghan SC, Schloss JA, Stracquadanio G, Trefzer A, Bader JS, Church GM, Coelho CM, Efcavitch JW, Güell M, et al. Technological challenges and milestones for writing genomes. Science (New York, N.Y.). 366: 310-312. PMID 31624201 DOI: 10.1126/science.aay0339  0.84
2019 Zullo JM, Drake D, Aron L, O'Hern P, Dhamne SC, Davidsohn N, Mao CA, Klein WH, Rotenberg A, Bennett DA, Church GM, Colaiácovo MP, Yankner BA. Regulation of lifespan by neural excitation and REST. Nature. 574: 359-364. PMID 31619788 DOI: 10.1038/s41586-019-1647-8  1
2019 Grishin D, Obbad K, Church GM. Author Correction: Data privacy in the age of personal genomics. Nature Biotechnology. PMID 31591553 DOI: 10.1038/s41587-019-0304-y  0.32
2019 Grishin D, Obbad K, Church GM. Data privacy in the age of personal genomics. Nature Biotechnology. 37: 1115-1117. PMID 31537915 DOI: 10.1038/s41587-019-0271-3  0.32
2019 Saka SK, Wang Y, Kishi JY, Zhu A, Zeng Y, Xie W, Kirli K, Yapp C, Cicconet M, Beliveau BJ, Lapan SW, Yin S, Lin M, Boyden ES, Kaeser PS, ... ... Church GM, et al. Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues. Nature Biotechnology. PMID 31427819 DOI: 10.1038/s41587-019-0207-y  0.76
2019 Scheiman J, Luber JM, Chavkin TA, MacDonald T, Tung A, Pham LD, Wibowo MC, Wurth RC, Punthambaker S, Tierney BT, Yang Z, Hattab MW, Avila-Pacheco J, Clish CB, Lessard S, ... Church GM, et al. Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism. Nature Medicine. PMID 31235964 DOI: 10.1038/s41591-019-0485-4  0.56
2019 Lee HH, Kalhor R, Goela N, Bolot J, Church GM. Terminator-free template-independent enzymatic DNA synthesis for digital information storage. Nature Communications. 10: 2383. PMID 31160595 DOI: 10.1038/s41467-019-10258-1  0.84
2019 Xiao Y, Muhuri M, Li S, Qin W, Xu G, Luo L, Li J, Letizia AJ, Wang SK, Chan YK, Wang C, Fuchs SP, Wang D, Su Q, Nahid MA, ... Church GM, et al. Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity. Jci Insight. 5. PMID 31112525 DOI: 10.1172/jci.insight.99052  0.76
2019 Lee HH, Ostrov N, Wong BG, Gold MA, Khalil AS, Church GM. Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi. Nature Microbiology. PMID 30962569 DOI: 10.1038/s41564-019-0423-8  0.84
2019 Shendure J, Balasubramanian S, Church GM, Gilbert W, Rogers J, Schloss JA, Waterston RH. Publisher Correction: DNA sequencing at 40: past, present and future. Nature. PMID 30948799 DOI: 10.1038/s41586-019-1120-8  1
2019 Noble C, Min J, Olejarz J, Buchthal J, Chavez A, Smidler AL, DeBenedictis EA, Church GM, Nowak MA, Esvelt KM. Daisy-chain gene drives for the alteration of local populations. Proceedings of the National Academy of Sciences of the United States of America. PMID 30940750 DOI: 10.1073/pnas.1716358116  0.72
2019 Wiegand DJ, Lee HH, Ostrov N, Church GM. Cell-free Protein Expression Using the Rapidly Growing Bacterium Vibrio natriegens. Journal of Visualized Experiments : Jove. PMID 30933074 DOI: 10.3791/59495  0.84
2019 Kaminski Strauss S, Schirman D, Jona G, Brooks AN, Kunjapur AM, Nguyen Ba AN, Flint A, Solt A, Mershin A, Dixit A, Yona AH, Csörgő B, Busby BP, Hennig BP, Pál C, ... ... Church GM, et al. Evolthon: A community endeavor to evolve lab evolution. Plos Biology. 17: e3000182. PMID 30925180 DOI: 10.1371/journal.pbio.3000182  0.76
2019 Zoltick ES, Linderman MD, McGinniss MA, Ramos E, Ball MP, Church GM, Leonard DGB, Pereira S, McGuire AL, Caskey CT, Sanderson SC, Schadt EE, Nielsen DE, Crawford SD, Green RC, et al. Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium. Genome Medicine. 11: 10. PMID 30808425 DOI: 10.1186/s13073-019-0619-9  0.68
2019 Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Reports. 26: 1112-1127.e9. PMID 30699343 DOI: 10.1016/j.celrep.2019.01.023  0.36
2019 Hoehe MR, Herwig R, Mao Q, Peters BA, Drmanac R, Church GM, Huebsch T. Significant abundance of cis configurations of coding variants in diploid human genomes. Nucleic Acids Research. PMID 30698752 DOI: 10.1093/nar/gkz031  1
2019 Caldwell BJ, Zakharova E, Filsinger GT, Wannier TM, Hempfling JP, Chun-Der L, Pei D, Church GM, Bell CE. Crystal structure of the Redβ C-terminal domain in complex with λ Exonuclease reveals an unexpected homology with λ Orf and an interaction with Escherichia coli single stranded DNA binding protein. Nucleic Acids Research. PMID 30624736 DOI: 10.1093/nar/gky1309  0.44
2018 Møller HD, Lin L, Xiang X, Petersen TS, Huang J, Yang L, Kjeldsen E, Jensen UB, Zhang X, Liu X, Xu X, Wang J, Yang H, Church GM, Bolund L, et al. CRISPR-C: circularization of genes and chromosome by CRISPR in human cells. Nucleic Acids Research. 46: e131. PMID 30551175 DOI: 10.1093/nar/gky767  0.72
2018 Nageshwaran S, Chavez A, Cher Yeo N, Guo X, Lance-Byrne A, Tung A, Collins JJ, Church GM. CRISPR Guide RNA Cloning for Mammalian Systems. Journal of Visualized Experiments : Jove. PMID 30346403 DOI: 10.3791/57998  0.96
2018 Brunk E, Chang RL, Xia J, Hefzi H, Yurkovich JT, Kim D, Buckmiller E, Wang HH, Cho BK, Yang C, Palsson BO, Church GM, Lewis NE. Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301795 DOI: 10.1073/pnas.1811971115  1
2018 Wiegand D, Lee HH, Ostrov N, Church GM. Establishing a cell-free Vibrio natriegens expression system. Acs Synthetic Biology. PMID 30160938 DOI: 10.1021/acssynbio.8b00222  0.84
2018 Kalhor R, Kalhor K, Mejia L, Leeper K, Graveline A, Mali P, Church GM. Developmental barcoding of whole mouse via homing CRISPR. Science (New York, N.Y.). PMID 30093604 DOI: 10.1126/science.aat9804  0.72
2018 Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, ... ... Church GM, et al. An enhanced CRISPR repressor for targeted mammalian gene regulation. Nature Methods. PMID 30013045 DOI: 10.1038/s41592-018-0048-5  0.96
2018 Musah S, Dimitrakakis N, Camacho DM, Church GM, Ingber DE. Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip. Nature Protocols. 13: 1662-1685. PMID 29995874 DOI: 10.1038/s41596-018-0007-8  0.84
2018 Clarke R, Heler R, MacDougall MS, Yeo NC, Chavez A, Regan M, Hanakahi L, Church GM, Marraffini LA, Merrill BJ. Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks. Molecular Cell. 71: 42-55.e8. PMID 29979968 DOI: 10.1016/j.molcel.2018.06.005  0.64
2018 Lubner JM, Balsbaugh JL, Church GM, Chou MF, Schwartz D. Characterizing Protein Kinase Substrate Specificity Using the Proteomic Peptide Library (ProPeL) Approach. Current Protocols in Chemical Biology. 10: e38. PMID 29927115 DOI: 10.1002/cpch.38  0.6
2018 Noble C, Adlam B, Church GM, Esvelt KM, Nowak MA. Current CRISPR gene drive systems are likely to be highly invasive in wild populations. Elife. 7. PMID 29916367 DOI: 10.7554/eLife.33423  0.72
2018 Guo X, Chavez A, Tung A, Chan Y, Kaas C, Yin Y, Cecchi R, Garnier SL, Kelsic ED, Schubert M, DiCarlo JE, Collins JJ, Church GM. High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR-Cas9 in yeast. Nature Biotechnology. PMID 29786095 DOI: 10.1038/nbt.4147  0.96
2018 Frumkin I, Lajoie MJ, Gregg CJ, Hornung G, Church GM, Pilpel Y. Codon usage of highly expressed genes affects proteome-wide translation efficiency. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735666 DOI: 10.1073/pnas.1719375115  1
2018 de Paz AM, Cybulski TR, Marblestone AH, Zamft BM, Church GM, Boyden ES, Kording KP, Tyo KEJ. High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing. Nucleic Acids Research. PMID 29718339 DOI: 10.1093/nar/gky296  0.76
2018 Farahany NA, Greely HT, Hyman S, Koch C, Grady C, Pașca SP, Sestan N, Arlotta P, Bernat JL, Ting J, Lunshof JE, Iyer EPR, Hyun I, Capestany BH, Church GM, et al. The ethics of experimenting with human brain tissue. Nature. 556: 429-432. PMID 29691509 DOI: 10.1038/d41586-018-04813-x  1
2018 Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP. An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance. Cell. 173: 649-664.e20. PMID 29677511 DOI: 10.1016/j.cell.2018.03.052  0.64
2018 Chan Y, Chan YK, Goodman DB, Guo X, Chavez A, Lim ET, Church GM. Enabling multiplexed testing of pooled donor cells through whole-genome sequencing. Genome Medicine. 10: 31. PMID 29673390 DOI: 10.1186/s13073-018-0541-6  1
2018 Chavez A, Pruitt BW, Tuttle M, Shapiro RS, Cecchi RJ, Winston J, Turczyk BM, Tung M, Collins JJ, Church GM. Precise Cas9 targeting enables genomic mutation prevention. Proceedings of the National Academy of Sciences of the United States of America. PMID 29555762 DOI: 10.1073/pnas.1718148115  0.96
2018 Wannier TM, Kunjapur AM, Rice DP, McDonald MJ, Desai MM, Church GM. Adaptive evolution of genomically recoded. Proceedings of the National Academy of Sciences of the United States of America. PMID 29440500 DOI: 10.1073/pnas.1715530115  0.76
2018 Nivala J, Shipman SL, Church GM. Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration. Nature Microbiology. PMID 29379209 DOI: 10.1038/s41564-017-0097-z  1
2018 Kohman RE, Kunjapur AM, Hysolli E, Wang Y, Church GM. From Designing the Molecules of Life to Designing Life: Future Applications Derived from Advances in DNA Technologies. Angewandte Chemie (International Ed. in English). PMID 29316123 DOI: 10.1002/anie.201707976  0.76
2018 Kunjapur AM, Stork DA, Kuru E, Vargas-Rodriguez O, Landon M, Söll D, Church GM. Engineering posttranslational proofreading to discriminate nonstandard amino acids. Proceedings of the National Academy of Sciences of the United States of America. PMID 29301968 DOI: 10.1073/pnas.1715137115  0.92
2017 Thompson DB, Aboulhouda S, Hysolli E, Smith CJ, Wang S, Castanon O, Church GM. The future of multiplexed eukaryotic genome engineering. Acs Chemical Biology. PMID 29241002 DOI: 10.1021/acschembio.7b00842  0.76
2017 Chen X, Sun YC, Church GM, Lee JH, Zador AM. Efficient in situ barcode sequencing using padlock probe-based BaristaSeq. Nucleic Acids Research. PMID 29190363 DOI: 10.1093/nar/gkx1206  0.88
2017 Shapiro RS, Chavez A, Porter CBM, Hamblin M, Kaas CS, DiCarlo JE, Zeng G, Xu X, Revtovich AV, Kirienko NV, Wang Y, Church GM, Collins JJ. A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans. Nature Microbiology. PMID 29062088 DOI: 10.1038/s41564-017-0043-0  0.96
2017 Musah S, Mammoto A, Ferrante TC, Jeanty SSF, Hirano-Kobayashi M, Mammoto T, Roberts K, Chung S, Novak R, Ingram M, Fatanat-Didar T, Koshy S, Weaver JC, Church GM, Ingber DE. Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. Nature Biomedical Engineering. 1. PMID 29038743 DOI: 10.1038/s41551-017-0069  0.84
2017 Shendure J, Balasubramanian S, Church GM, Gilbert W, Rogers J, Schloss JA, Waterston RH. DNA sequencing at 40: past, present and future. Nature. PMID 29019985 DOI: 10.1038/nature24286  1
2017 Cho YS, Kim H, Kim HM, Jho S, Jun J, Lee YJ, Chae KS, Kim CG, Kim S, Eriksson A, Edwards JS, Lee S, Kim BC, Manica A, Oh TK, ... Church GM, et al. Corrigendum: An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes. Nature Communications. 8: 16168. PMID 28991236 DOI: 10.1038/ncomms16168  0.96
2017 Fang L, Guell M, Church GM, Pfeifer BA. Heterologous Erythromycin Production across Strain and Plasmid Construction. Biotechnology Progress. PMID 28960932 DOI: 10.1002/btpr.2567  0.68
2017 Wang Y, Woehrstein JB, Donoghue N, Dai M, Avendano MS, Schackmann RCJ, Zoeller J, Wang SSH, Tillberg PW, Park D, Lapan SW, Boyden ES, Brugge JS, Kaeser PS, Church G, et al. Rapid sequential in situ multiplexing with DNA-Exchange-Imaging in Neuronal Cells and Tissues. Nano Letters. PMID 28933153 DOI: 10.1021/acs.nanolett.7b02716  0.76
2017 Lubock NB, Zhang D, Sidore AM, Church GM, Kosuri S. A systematic comparison of error correction enzymes by next-generation sequencing. Nucleic Acids Research. 45: 9206-9217. PMID 28911123 DOI: 10.1093/nar/gkx691  1
2017 Chari R, Church GM. Beyond editing to writing large genomes. Nature Reviews. Genetics. PMID 28852223 DOI: 10.1038/nrg.2017.59  0.64
2017 Niu D, Wei HJ, Lin L, George H, Wang T, Lee IH, Zhao HY, Wang Y, Kan Y, Shrock E, Lesha E, Wang G, Luo Y, Qing Y, Jiao D, ... ... Church GM, et al. Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9. Science (New York, N.Y.). PMID 28798043 DOI: 10.1126/science.aan4187  0.76
2017 Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, D'Gama AM, Kim SN, Hill RS, Goldberg AP, Poultney C, Minshew NJ, Kushima I, Aleksic B, Ozaki N, ... ... Church GM, et al. Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nature Neuroscience. PMID 28714951 DOI: 10.1038/nn.4598  0.36
2017 Li J, Zhang C, Huang P, Kuru E, Forster-Benson ETC, Li T, Church GM. Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system. Translation (Austin, Tex.). 5: e1327006. PMID 28702280 DOI: 10.1080/21690731.2017.1327006  0.76
2017 Shipman SL, Nivala J, Macklis JD, Church GM. CRISPR-Cas encoding of a digital movie into the genomes of a population of living bacteria. Nature. PMID 28700573 DOI: 10.1038/nature23017  1
2017 Giwa S, Lewis JK, Alvarez L, Langer R, Roth AE, Church GM, Markmann JF, Sachs DH, Chandraker A, Wertheim JA, Rothblatt M, Boyden ES, Eidbo E, Lee WPA, Pomahac B, et al. The promise of organ and tissue preservation to transform medicine. Nature Biotechnology. 35: 530-542. PMID 28591112 DOI: 10.1038/nbt.3889  0.6
2017 Madison AC, Royal MW, Vigneault F, Chen L, Griffin PB, Horowitz M, Church GM, Fair RB. A scalable device for automated microbial electroporation in a digital microfluidic platform. Acs Synthetic Biology. PMID 28569062 DOI: 10.1021/acssynbio.7b00007  1
2017 Goodman DB, Kuznetsov G, Lajoie MJ, Ahern BW, Napolitano MG, Chen KY, Chen C, Church GM. Millstone: software for multiplex microbial genome analysis and engineering. Genome Biology. 18: 101. PMID 28545559 DOI: 10.1186/s13059-017-1223-1  1
2017 Kuznetsov G, Goodman DB, Filsinger GT, Landon M, Rohland N, Aach J, Lajoie MJ, Church GM. Optimizing complex phenotypes through model-guided multiplex genome engineering. Genome Biology. 18: 100. PMID 28545477 DOI: 10.1186/s13059-017-1217-z  1
2017 Aach J, Lunshof J, Iyer E, Church GM. Correction: Addressing the ethical issues raised by synthetic human entities with embryo-like features. Elife. 6. PMID 28494857 DOI: 10.7554/eLife.27642  0.96
2017 Aach J, Lunshof J, Iyer E, Church GM. Addressing the ethical issues raised by synthetic human entities with embryo-like features. Elife. 6. PMID 28494856 DOI: 10.7554/eLife.20674  0.96
2017 Cybulski TR, Boyden ES, Church GM, Tyo KEJ, Kording KP. Nucleotide-time alignment for molecular recorders. Plos Computational Biology. 13: e1005483. PMID 28459860 DOI: 10.1371/journal.pcbi.1005483  0.6
2017 Noble C, Olejarz J, Esvelt KM, Church GM, Nowak MA. Evolutionary dynamics of CRISPR gene drives. Science Advances. 3: e1601964. PMID 28435878 DOI: 10.1126/sciadv.1601964  0.72
2017 Chan Y, Tung M, Garruss AS, Zaranek SW, Chan YK, Lunshof JE, Zaranek AW, Ball MP, Chou MF, Lim ET, Church GM. An unbiased index to quantify participant's phenotypic contribution to an open-access cohort. Scientific Reports. 7: 46148. PMID 28387241 DOI: 10.1038/srep46148  0.72
2017 Li J, Haas W, Jackson K, Kuru E, Jewett MC, Fan ZH, Gygi SP, Church GM. Co-generating synthetic parts toward a self-replicating system. Acs Synthetic Biology. PMID 28330337 DOI: 10.1021/acssynbio.6b00342  0.76
2017 Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM. Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform. Nature Microbiology. 2: 16274. PMID 28165460 DOI: 10.1038/nmicrobiol.2016.274  0.64
2017 Chari R, Yeo NC, Chavez A, Church GM. sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity. Acs Synthetic Biology. PMID 28146356 DOI: 10.1021/acssynbio.6b00343  0.64
2017 Lubner JM, Dodge-Kafka KL, Carlson CR, Church GM, Chou MF, Schwartz D. Cushing's syndrome mutant PKA(L)(205R) exhibits altered substrate specificity. Febs Letters. 591: 459-467. PMID 28100013 DOI: 10.1002/1873-3468.12562  0.6
2017 Wang G, Yang L, Grishin D, Rios X, Ye LY, Hu Y, Li K, Zhang D, Church GM, Pu WT. Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies. Nature Protocols. 12: 88-103. PMID 27929521 DOI: 10.1038/nprot.2016.152  1
2017 Kalhor R, Mali P, Church GM. Rapidly evolving homing CRISPR barcodes. Nature Methods. 14: 195-200. PMID 27918539 DOI: 10.1038/nmeth.4108  0.72
2016 Cho YS, Kim H, Kim HM, Jho S, Jun J, Lee YJ, Chae KS, Kim CG, Kim S, Eriksson A, Edwards JS, Lee S, Kim BC, Manica A, Oh TK, ... Church GM, et al. An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes. Nature Communications. 7: 13637. PMID 27882922 DOI: 10.1038/ncomms13637  0.96
2016 Soares AE, Novak BJ, Haile J, Heupink TH, Fjeldså J, Gilbert MT, Poinar H, Church GM, Shapiro B. Complete mitochondrial genomes of living and extinct pigeons revise the timing of the columbiform radiation. Bmc Evolutionary Biology. 16: 230. PMID 27782796 DOI: 10.1186/s12862-016-0800-3  0.04
2016 Stranges PB, Palla M, Kalachikov S, Nivala J, Dorwart M, Trans A, Kumar S, Porel M, Chien M, Tao C, Morozova I, Li Z, Shi S, Aberra A, Arnold C, ... ... Church GM, et al. Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array. Proceedings of the National Academy of Sciences of the United States of America. 113: E6749-E6756. PMID 27729524 DOI: 10.1073/pnas.1608271113  1
2016 Mao Q, Ciotlos S, Zhang RY, Ball MP, Chin R, Carnevali P, Barua N, Nguyen S, Agarwal MR, Clegg T, Connelly A, Vandewege W, Zaranek AW, Estep PW, Church GM, et al. The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes. Gigascience. 5: 42. PMID 27724973 DOI: 10.1186/s13742-016-0148-z  0.96
2016 Napolitano MG, Landon M, Gregg CJ, Lajoie MJ, Govindarajan L, Mosberg JA, Kuznetsov G, Goodman DB, Vargas-Rodriguez O, Isaacs FJ, Söll D, Church GM. Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 113: E5588-97. PMID 27601680 DOI: 10.1073/pnas.1605856113  1
2016 Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM. A multifunctional AAV-CRISPR-Cas9 and its host response. Nature Methods. 13: 868-74. PMID 27595405 DOI: 10.1038/nmeth.3993  0.72
2016 Vasiliou SK, Diamandis EP, Church GM, Greely HT, Baylis F, Thompson C, Schmitt-Ulms G. CRISPR-Cas9 System: Opportunities and Concerns. Clinical Chemistry. 62: 1304-11. PMID 27551006 DOI: 10.1373/clinchem.2016.263186  0.24
2016 Ostrov N, Landon M, Guell M, Kuznetsov G, Teramoto J, Cervantes N, Zhou M, Singh K, Napolitano MG, Moosburner M, Shrock E, Pruitt BW, Conway N, Goodman DB, Gardner CL, ... ... Church GM, et al. Design, synthesis, and testing toward a 57-codon genome. Science (New York, N.Y.). 353: 819-22. PMID 27540174 DOI: 10.1126/science.aaf3639  1
2016 Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES. Nanoscale imaging of RNA with expansion microscopy. Nature Methods. 13: 679-84. PMID 27376770 DOI: 10.1038/nmeth.3899  1
2016 Shipman SL, Nivala J, Macklis JD, Church GM. Molecular recordings by directed CRISPR spacer acquisition. Science (New York, N.Y.). 353: aaf1175. PMID 27284167 DOI: 10.1126/science.aaf1175  1
2016 Zook JM, Catoe D, McDaniel J, Vang L, Spies N, Sidow A, Weng Z, Liu Y, Mason CE, Alexander N, Henaff E, McIntyre AB, Chandramohan D, Chen F, Jaeger E, ... ... Church GM, et al. Extensive sequencing of seven human genomes to characterize benchmark reference materials. Scientific Data. 3: 160025. PMID 27271295 DOI: 10.1038/sdata.2016.25  0.72
2016 Braff JL, Yaung SJ, Esvelt KM, Church GM. Characterization of Cas9-Guide RNA Orthologs. Cold Spring Harbor Protocols. 2016: pdb.top086793. PMID 27140923 DOI: 10.1101/pdb.top086793  0.72
2016 Braff JL, Yaung SJ, Esvelt KM, Church GM. Characterizing Cas9 Protospacer-Adjacent Motifs with High-Throughput Sequencing of Library Depletion Experiments. Cold Spring Harbor Protocols. 2016: pdb.prot090183. PMID 27140916 DOI: 10.1101/pdb.prot090183  0.72
2016 Fuller CW, Kumar S, Porel M, Chien M, Bibillo A, Stranges PB, Dorwart M, Tao C, Li Z, Guo W, Shi S, Korenblum D, Trans A, Aguirre A, Liu E, ... ... Church GM, et al. Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array. Proceedings of the National Academy of Sciences of the United States of America. 113: 5233-8. PMID 27091962 DOI: 10.1073/pnas.1601782113  0.88
2016 Zheng Y, Lajoie MJ, Italia JS, Chin MA, Church GM, Chatterjee A. Performance of optimized noncanonical amino acid mutagenesis systems in the absence of release factor 1. Molecular Biosystems. 12: 1746-9. PMID 27027374 DOI: 10.1039/c6mb00070c  1
2016 Zhirnov V, Zadegan RM, Sandhu GS, Church GM, Hughes WL. Nucleic acid memory. Nature Materials. 15: 366-70. PMID 27005909 DOI: 10.1038/nmat4594  0.12
2016 Rogers JK, Taylor ND, Church GM. Biosensor-based engineering of biosynthetic pathways. Current Opinion in Biotechnology. 42: 84-91. PMID 26998575 DOI: 10.1016/j.copbio.2016.03.005  0.6
2016 Krueger AS, Munck C, Dantas G, Church GM, Galagan J, Lehár J, Sommer MO. Simulating Serial-Target Antibacterial Drug Synergies Using Flux Balance Analysis. Plos One. 11: e0147651. PMID 26821252 DOI: 10.1371/journal.pone.0147651  0.6
2016 Tabebordbar M, Zhu K, Cheng JK, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ. In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Science (New York, N.Y.). 351: 407-11. PMID 26721686 DOI: 10.1126/science.aad5177  0.96
2016 Biteen JS, Blainey PC, Cardon ZG, Chun M, Church GM, Dorrestein PC, Fraser SE, Gilbert JA, Jansson JK, Knight R, Miller JF, Ozcan A, Prather KA, Quake SR, Ruby EG, et al. Tools for the Microbiome: Nano and Beyond. Acs Nano. 10: 6-37. PMID 26695070 DOI: 10.1021/acsnano.5b07826  1
2016 Taylor ND, Garruss AS, Moretti R, Chan S, Arbing MA, Cascio D, Rogers JK, Isaacs FJ, Kosuri S, Baker D, Fields S, Church GM, Raman S. Engineering an allosteric transcription factor to respond to new ligands. Nature Methods. 13: 177-83. PMID 26689263 DOI: 10.1038/nmeth.3696  1
2016 Ho JM, Reynolds NM, Rivera K, Connolly M, Guo LT, Ling J, Pappin DJ, Church GM, Söll D. Efficient Reassignment of a Frequent Serine Codon in Wild-Type Escherichia coli. Acs Synthetic Biology. 5: 163-71. PMID 26544153 DOI: 10.1021/acssynbio.5b00197  0.92
2015 Church GM. Precision Chemistry for Precision Medicine. Acs Central Science. 1: 11-3. PMID 27162939 DOI: 10.1021/acscentsci.5b00088  0.01
2015 Byrne SM, Church GM. Crispr-mediated Gene Targeting of Human Induced Pluripotent Stem Cells. Current Protocols in Stem Cell Biology. 35: 5A.8.1-22. PMID 26949444 DOI: 10.1002/9780470151808.sc05a08s35  0.2
2015 Feng J, Jester BW, Tinberg CE, Mandell DJ, Antunes MS, Chari R, Morey KJ, Rios X, Medford JI, Church GM, Fields S, Baker D. A general strategy to construct small molecule biosensors in eukaryotes. Elife. 4. PMID 26714111 DOI: 10.7554/eLife.10606  0.72
2015 Church G. Perspective: Encourage the innovators. Nature. 528: S7. PMID 26630599 DOI: 10.1038/528S7a  1
2015 Yetisen AK, Davis J, Coskun AF, Church GM, Hyun Yun S. Bioart. Trends in Biotechnology. 33: 724-34. PMID 26617334 DOI: 10.1016/j.tibtech.2015.09.011  0.24
2015 DiCarlo JE, Chavez A, Dietz SL, Esvelt KM, Church GM. Safeguarding CRISPR-Cas9 gene drives in yeast. Nature Biotechnology. 33: 1250-1255. PMID 26571100 DOI: 10.1038/nbt.3412  0.72
2015 Tsioris K, Gupta NT, Ogunniyi AO, Zimnisky RM, Qian F, Yao Y, Wang X, Stern JN, Chari R, Briggs AW, Clouser CR, Vigneault F, Church GM, Garcia MN, Murray KO, et al. Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 1587-97. PMID 26481611 DOI: 10.1039/c5ib00169b  1
2015 Alivisatos AP, Chun M, Church GM, Greenspan RJ, Roukes ML, Yuste R. A National Network of Neurotechnology Centers for the BRAIN Initiative. Neuron. 88: 445-8. PMID 26481036 DOI: 10.1016/j.neuron.2015.10.015  1
2015 Yang L, Güell M, Niu D, George H, Lesha E, Grishin D, Aach J, Shrock E, Xu W, Poci J, Cortazio R, Wilkinson RA, Fishman JA, Church G. Genome-wide inactivation of porcine endogenous retroviruses (PERVs). Science (New York, N.Y.). PMID 26456528 DOI: 10.1126/science.aad1191  1
2015 Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM. Corrigendum: Biocontainment of genetically modified organisms by synthetic protein design. Nature. 527: 264. PMID 26416745 DOI: 10.1038/nature15536  1
2015 Lajoie MJ, Söll D, Church GM. Overcoming challenges in engineering the genetic code. Journal of Molecular Biology. PMID 26348789 DOI: 10.1016/j.jmb.2015.09.003  0.92
2015 Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/science.aac7932  0.72
2015 Glaser JI, Zamft BM, Church GM, Kording KP. Puzzle Imaging: Using Large-Scale Dimensionality Reduction Algorithms for Localization. Plos One. 10: e0131593. PMID 26192446 DOI: 10.1371/journal.pone.0131593  0.6
2015 Chari R, Mali P, Moosburner M, Church GM. Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach. Nature Methods. 12: 823-6. PMID 26167643 DOI: 10.1038/nmeth.3473  0.72
2015 Rogers JK, Guzman CD, Taylor ND, Raman S, Anderson K, Church GM. Synthetic biosensors for precise gene control and real-time monitoring of metabolites. Nucleic Acids Research. 43: 7648-60. PMID 26152303 DOI: 10.1093/nar/gkv616  0.72
2015 Yaung SJ, Deng L, Li N, Braff JL, Church GM, Bry L, Wang HH, Gerber GK. Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics. Molecular Systems Biology. 11: 788. PMID 26148351  1
2015 Petit E, Coppi MV, Hayes JC, Tolonen AC, Warnick T, Latouf WG, Amisano D, Biddle A, Mukherjee S, Ivanova N, Lykidis A, Land M, Hauser L, Kyrpides N, Henrissat B, ... ... Church GM, et al. Genome and Transcriptome of Clostridium phytofermentans, Catalyst for the Direct Conversion of Plant Feedstocks to Fuels. Plos One. 10: e0118285. PMID 26035711 DOI: 10.1371/journal.pone.0118285  1
2015 Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, et al. Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science (New York, N.Y.). 348: 36-8. PMID 25791083 DOI: 10.1126/science.aab1028  1
2015 Yaung SJ, Deng L, Li N, Braff JL, Church GM, Bry L, Wang HH, Gerber GK. Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics. Molecular Systems Biology. 11: 788. PMID 25762151 DOI: 10.15252/msb.20145866  1
2015 Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, ... ... Church GM, et al. Highly efficient Cas9-mediated transcriptional programming. Nature Methods. 12: 326-8. PMID 25730490 DOI: 10.1038/nmeth.3312  1
2015 Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Ferrante TC, Terry R, Turczyk BM, Yang JL, Lee HS, Aach J, Zhang K, Church GM. Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues. Nature Protocols. 10: 442-58. PMID 25675209 DOI: 10.1038/nprot.2014.191  0.96
2015 Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM. Biocontainment of genetically modified organisms by synthetic protein design. Nature. 518: 55-60. PMID 25607366 DOI: 10.1038/nature14121  1
2015 Yaung SJ, Esvelt KM, Church GM. Complete Genome Sequences of T4-Like Bacteriophages RB3, RB5, RB6, RB7, RB9, RB10, RB27, RB33, RB55, RB59, and RB68. Genome Announcements. 3. PMID 25555735 DOI: 10.1128/genomeA.01122-14  0.72
2015 Drmanac R, Peters BA, Church GM, Reid CA, Xu X. Accurate whole genome sequencing as the ultimate genetic test. Clinical Chemistry. 61: 305-6. PMID 25479756 DOI: 10.1373/clinchem.2014.224907  0.6
2015 Byrne SM, Ortiz L, Mali P, Aach J, Church GM. Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells. Nucleic Acids Research. 43: e21. PMID 25414332 DOI: 10.1093/nar/gku1246  1
2015 Bonde MT, Kosuri S, Genee HJ, Sarup-Lytzen K, Church GM, Sommer MO, Wang HH. Direct mutagenesis of thousands of genomic targets using microarray-derived oligonucleotides. Acs Synthetic Biology. 4: 17-22. PMID 24856730 DOI: 10.1021/sb5001565  1
2015 Tolonen AC, Cerisy T, El-Sayyed H, Boutard M, Salanoubat M, Church GM. Fungal lysis by a soil bacterium fermenting cellulose. Environmental Microbiology. 17: 2618-27. PMID 24798076 DOI: 10.1111/1462-2920.12495  0.16
2015 Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, ... ... Church G, et al. Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes Cell Metabolism. 22: 239-252. DOI: 10.1016/j.cmet.2015.07.015  1
2014 Cybulski TR, Glaser JI, Marblestone AH, Zamft BM, Boyden ES, Church GM, Kording KP. Spatial information in large-scale neural recordings. Frontiers in Computational Neuroscience. 8: 172. PMID 25653613 DOI: 10.3389/fncom.2014.00172  0.76
2014 Raman S, Rogers JK, Taylor ND, Church GM. Evolution-guided optimization of biosynthetic pathways. Proceedings of the National Academy of Sciences of the United States of America. 111: 17803-8. PMID 25453111 DOI: 10.1073/pnas.1409523111  0.72
2014 Yang L, Grishin D, Wang G, Aach J, Zhang CZ, Chari R, Homsy J, Cai X, Zhao Y, Fan JB, Seidman C, Seidman J, Pu W, Church G. Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells. Nature Communications. 5: 5507. PMID 25425480 DOI: 10.1038/ncomms6507  1
2014 Hoehe MR, Church GM, Lehrach H, Kroslak T, Palczewski S, Nowick K, Schulz S, Suk EK, Huebsch T. Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes. Nature Communications. 5: 5569. PMID 25424553 DOI: 10.1038/ncomms6569  0.48
2014 Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM. Rapid neurogenesis through transcriptional activation in human stem cells. Molecular Systems Biology. 10: 760. PMID 25403753  1
2014 Byrne SM, Mali P, Church GM. Genome editing in human stem cells. Methods in Enzymology. 546: 119-38. PMID 25398338 DOI: 10.1016/B978-0-12-801185-0.00006-4  1
2014 Raman S, Taylor N, Genuth N, Fields S, Church GM. Engineering allostery. Trends in Genetics : Tig. 30: 521-8. PMID 25306102 DOI: 10.1016/j.tig.2014.09.004  0.72
2014 Gu L, Li C, Aach J, Hill DE, Vidal M, Church GM. Multiplex single-molecule interaction profiling of DNA-barcoded proteins. Nature. 515: 554-7. PMID 25252978 DOI: 10.1038/nature13761  0.96
2014 Li J, Gu L, Aach J, Church GM. Improved cell-free RNA and protein synthesis system. Plos One. 9: e106232. PMID 25180701 DOI: 10.1371/journal.pone.0106232  0.96
2014 Stern JN, Yaari G, Vander Heiden JA, Church G, Donahue WF, Hintzen RQ, Huttner AJ, Laman JD, Nagra RM, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH, et al. B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes. Science Translational Medicine. 6: 248ra107. PMID 25100741 DOI: 10.1126/scitranslmed.3008879  1
2014 Esvelt KM, Smidler AL, Catteruccia F, Church GM. Concerning RNA-guided gene drives for the alteration of wild populations. Elife. 3. PMID 25035423 DOI: 10.7554/eLife.03401  0.72
2014 Oye KA, Esvelt K, Appleton E, Catteruccia F, Church G, Kuiken T, Lightfoot SB, McNamara J, Smidler A, Collins JP. Biotechnology. Regulating gene drives. Science (New York, N.Y.). 345: 626-8. PMID 25035410 DOI: 10.1126/science.1254287  1
2014 Güell M, Yang L, Church GM. Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA). Bioinformatics (Oxford, England). 30: 2968-70. PMID 24990609 DOI: 10.1093/bioinformatics/btu427  0.72
2014 Yang L, Yang JL, Byrne S, Pan J, Church GM. CRISPR/Cas9-Directed Genome Editing of Cultured Cells. Current Protocols in Molecular Biology. 107: 31.1.1-17. PMID 24984853 DOI: 10.1002/0471142727.mb3101s107  0.72
2014 Yaung SJ, Esvelt KM, Church GM. CRISPR/Cas9-mediated phage resistance is not impeded by the DNA modifications of phage T4. Plos One. 9: e98811. PMID 24886988 DOI: 10.1371/journal.pone.0098811  0.72
2014 Chatterjee A, Lajoie MJ, Xiao H, Church GM, Schultz PG. A bacterial strain with a unique quadruplet codon specifying non-native amino acids. Chembiochem : a European Journal of Chemical Biology. 15: 1782-6. PMID 24867343 DOI: 10.1002/cbic.201402104  1
2014 Montague TG, Cruz JM, Gagnon JA, Church GM, Valen E. CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing. Nucleic Acids Research. 42: W401-7. PMID 24861617 DOI: 10.1093/nar/gku410  0.12
2014 Yaung SJ, Church GM, Wang HH. Recent progress in engineering human-associated microbiomes. Methods in Molecular Biology (Clifton, N.J.). 1151: 3-25. PMID 24838875 DOI: 10.1007/978-1-4939-0554-6_1  1
2014 Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, ... ... Church GM, et al. Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Nature Medicine. 20: 616-23. PMID 24813252 DOI: 10.1038/nm.3545  1
2014 Kosuri S, Church GM. Large-scale de novo DNA synthesis: technologies and applications. Nature Methods. 11: 499-507. PMID 24781323 DOI: 10.1038/nmeth.2918  1
2014 Mee MT, Collins JJ, Church GM, Wang HH. Syntrophic exchange in synthetic microbial communities. Proceedings of the National Academy of Sciences of the United States of America. 111: E2149-56. PMID 24778240 DOI: 10.1073/pnas.1405641111  1
2014 Ball MP, Bobe JR, Chou MF, Clegg T, Estep PW, Lunshof JE, Vandewege W, Zaranek A, Church GM. Harvard Personal Genome Project: lessons from participatory public research. Genome Medicine. 6: 10. PMID 24713084 DOI: 10.1186/gm527  0.96
2014 Yuste R, Church GM. The new century of the brain. Scientific American. 310: 38-45. PMID 24660326  1
2014 Laserson U, Vigneault F, Gadala-Maria D, Yaari G, Uduman M, Vander Heiden JA, Kelton W, Taek Jung S, Liu Y, Laserson J, Chari R, Lee JH, Bachelet I, Hickey B, Lieberman-Aiden E, ... ... Church GM, et al. High-resolution antibody dynamics of vaccine-induced immune responses. Proceedings of the National Academy of Sciences of the United States of America. 111: 4928-33. PMID 24639495 DOI: 10.1073/pnas.1323862111  1
2014 Church GM, Elowitz MB, Smolke CD, Voigt CA, Weiss R. Realizing the potential of synthetic biology. Nature Reviews. Molecular Cell Biology. 15: 289-94. PMID 24622617 DOI: 10.1038/nrm3767  0.04
2014 Lunshof JE, Church GM, Prainsack B. Raw data: access to inaccuracy--response. Science (New York, N.Y.). 343: 969. PMID 24578564 DOI: 10.1126/science.343.6174.969-a  0.52
2014 Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Yang JL, Ferrante TC, Terry R, Jeanty SS, Li C, Amamoto R, Peters DT, Turczyk BM, Marblestone AH, Inverso SA, Bernard A, ... ... Church GM, et al. Highly multiplexed subcellular RNA sequencing in situ. Science (New York, N.Y.). 343: 1360-3. PMID 24578530 DOI: 10.1126/science.1250212  0.96
2014 Yang L, Mali P, Kim-Kiselak C, Church G. CRISPR-Cas-mediated targeted genome editing in human cells. Methods in Molecular Biology (Clifton, N.J.). 1114: 245-67. PMID 24557908 DOI: 10.1007/978-1-62703-761-7_16  1
2014 Bröcker MJ, Ho JM, Church GM, Söll D, O'Donoghue P. Recoding the genetic code with selenocysteine. Angewandte Chemie (International Ed. in English). 53: 319-23. PMID 24511637  0.92
2014 Lunshof JE, Church GM, Prainsack B. Information access. Raw personal data: providing access. Science (New York, N.Y.). 343: 373-4. PMID 24458627 DOI: 10.1126/science.1249382  0.52
2014 Gregg CJ, Lajoie MJ, Napolitano MG, Mosberg JA, Goodman DB, Aach J, Isaacs FJ, Church GM. Rational optimization of tolC as a powerful dual selectable marker for genome engineering. Nucleic Acids Research. 42: 4779-90. PMID 24452804 DOI: 10.1093/nar/gkt1374  1
2014 Uduman M, Shlomchik MJ, Vigneault F, Church GM, Kleinstein SH. Integrating B cell lineage information into statistical tests for detecting selection in Ig sequences. Journal of Immunology (Baltimore, Md. : 1950). 192: 867-74. PMID 24376267 DOI: 10.4049/jimmunol.1301551  1
2014 Robasky K, Lewis NE, Church GM. The role of replicates for error mitigation in next-generation sequencing. Nature Reviews. Genetics. 15: 56-62. PMID 24322726 DOI: 10.1038/nrg3655  0.84
2014 Ling J, Daoud R, Lajoie MJ, Church GM, Söll D, Lang BF. Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria. Nucleic Acids Research. 42: 499-508. PMID 24049072 DOI: 10.1093/nar/gkt842  1
2014 Umbarger MA, Kennedy CJ, Saunders P, Breton B, Chennagiri N, Emhoff J, Greger V, Hallam S, Maganzini D, Micale C, Nizzari MM, Towne CF, Church GM, Porreca GJ. Next-generation carrier screening. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 16: 132-40. PMID 23765052 DOI: 10.1038/gim.2013.83  0.96
2014 Drukier AK, Cantor C, Chonofsky M, Church GM, Fagaly RL, Freese K, Lopez A, Sano T, Savage C, Wong WP. New class of biological detectors for WIMPs International Journal of Modern Physics A. 29. DOI: 10.1142/S0217751X14430076  1
2013 Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, ... ... Church GM, et al. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies. Plos Pathogens. 9: e1003754. PMID 24278016 DOI: 10.1371/journal.ppat.1003754  1
2013 Marblestone AH, Zamft BM, Maguire YG, Shapiro MG, Cybulski TR, Glaser JI, Amodei D, Stranges PB, Kalhor R, Dalrymple DA, Seo D, Alon E, Maharbiz MM, Carmena JM, Rabaey JM, ... ... Church GM, et al. Physical principles for scalable neural recording. Frontiers in Computational Neuroscience. 7: 137. PMID 24187539 DOI: 10.3389/fncom.2013.00137  0.76
2013 Church GM. BRAIN: innovative neurotechnologies for imaging and therapeutics. Dialogues in Clinical Neuroscience. 15: 241-3. PMID 24174897  0.01
2013 Li JB, Church GM. Deciphering the functions and regulation of brain-enriched A-to-I RNA editing. Nature Neuroscience. 16: 1518-22. PMID 24165678 DOI: 10.1038/nn.3539  0.96
2013 DiCarlo JE, Conley AJ, Penttilä M, Jäntti J, Wang HH, Church GM. Yeast oligo-mediated genome engineering (YOGE). Acs Synthetic Biology. 2: 741-9. PMID 24160921 DOI: 10.1021/sb400117c  1
2013 Lajoie MJ, Kosuri S, Mosberg JA, Gregg CJ, Zhang D, Church GM. Probing the limits of genetic recoding in essential genes. Science (New York, N.Y.). 342: 361-3. PMID 24136967 DOI: 10.1126/science.1241460  1
2013 Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, et al. Genomically recoded organisms expand biological functions. Science (New York, N.Y.). 342: 357-60. PMID 24136966 DOI: 10.1126/science.1241459  1
2013 Church G. Improving genome understanding. Nature. 502: 143. PMID 24108012 DOI: 10.1038/502143a  1
2013 O'Shea JP, Chou MF, Quader SA, Ryan JK, Church GM, Schwartz D. pLogo: a probabilistic approach to visualizing sequence motifs. Nature Methods. 10: 1211-2. PMID 24097270 DOI: 10.1038/nmeth.2646  0.6
2013 Mali P, Esvelt KM, Church GM. Cas9 as a versatile tool for engineering biology. Nature Methods. 10: 957-63. PMID 24076990 DOI: 10.1038/nmeth.2649  0.72
2013 Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nature Methods. 10: 1116-21. PMID 24076762 DOI: 10.1038/nmeth.2681  0.72
2013 Goodman DB, Church GM, Kosuri S. Causes and effects of N-terminal codon bias in bacterial genes. Science (New York, N.Y.). 342: 475-9. PMID 24072823 DOI: 10.1126/science.1241934  1
2013 Eroshenko N, Church GM. Mutants of Cre recombinase with improved accuracy. Nature Communications. 4: 2509. PMID 24056590 DOI: 10.1038/ncomms3509  0.68
2013 Lo C, Liu R, Lee J, Robasky K, Byrne S, Lucchesi C, Aach J, Church G, Bafna V, Zhang K. On the design of clone-based haplotyping. Genome Biology. 14: R100. PMID 24028704 DOI: 10.1186/gb-2013-14-9-r100  1
2013 Church G. Please reanimate. Scientific American. 309: 12. PMID 24003542 DOI: 10.1038/scientificamerican0913-12  1
2013 Tzur YB, Friedland AE, Nadarajan S, Church GM, Calarco JA, Colaiácovo MP. Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system. Genetics. 195: 1181-5. PMID 23979579 DOI: 10.1534/genetics.113.156075  0.44
2013 Payne AC, Andregg M, Kemmish K, Hamalainen M, Bowell C, Bleloch A, Klejwa N, Lehrach W, Schatz K, Stark H, Marblestone A, Church G, Own CS, Andregg W. Molecular threading: mechanical extraction, stretching and placement of DNA molecules from a liquid-air interface. Plos One. 8: e69058. PMID 23935923 DOI: 10.1371/journal.pone.0069058  1
2013 Li JF, Norville JE, Aach J, McCormack M, Zhang D, Bush J, Church GM, Sheen J. Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nature Biotechnology. 31: 688-91. PMID 23929339 DOI: 10.1038/nbt.2654  1
2013 Kosuri S, Goodman DB, Cambray G, Mutalik VK, Gao Y, Arkin AP, Endy D, Church GM. Composability of regulatory sequences controlling transcription and translation in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 110: 14024-9. PMID 23924614 DOI: 10.1073/pnas.1301301110  1
2013 Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G. Optimization of scarless human stem cell genome editing. Nucleic Acids Research. 41: 9049-61. PMID 23907390 DOI: 10.1093/nar/gkt555  1
2013 Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nature Biotechnology. 31: 833-8. PMID 23907171 DOI: 10.1038/nbt.2675  1
2013 Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Optical control of mammalian endogenous transcription and epigenetic states. Nature. 500: 472-6. PMID 23877069 DOI: 10.1038/nature12466  0.96
2013 Glaser JI, Zamft BM, Marblestone AH, Moffitt JR, Tyo K, Boyden ES, Church G, Kording KP. Statistical analysis of molecular signal recording. Plos Computational Biology. 9: e1003145. PMID 23874187 DOI: 10.1371/journal.pcbi.1003145  1
2013 Eminaga S, Christodoulou DC, Vigneault F, Church GM, Seidman JG. Quantification of microRNA expression with next-generation sequencing. Current Protocols in Molecular Biology. Unit 4.17. PMID 23821442 DOI: 10.1002/0471142727.mb0417s103  1
2013 Friedland AE, Tzur YB, Esvelt KM, Colaiácovo MP, Church GM, Calarco JA. Heritable genome editing in C. elegans via a CRISPR-Cas9 system. Nature Methods. 10: 741-3. PMID 23817069 DOI: 10.1038/nmeth.2532  1
2013 Jewett MC, Fritz BR, Timmerman LE, Church GM. In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation. Molecular Systems Biology. 9: 678. PMID 23799452 DOI: 10.1038/msb.2013.31  0.32
2013 Alivisatos AP, Andrews AM, Boyden ES, Chun M, Church GM, Deisseroth K, Donoghue JP, Fraser SE, Lippincott-Schwartz J, Looger LL, Masmanidis S, McEuen PL, Nurmikko AV, Park H, Peterka DS, et al. Nanotools for neuroscience and brain activity mapping. Acs Nano. 7: 1850-66. PMID 23514423 DOI: 10.1021/nn4012847  1
2013 Zhu J, Larman HB, Gao G, Somwar R, Zhang Z, Laserson U, Ciccia A, Pavlova N, Church G, Zhang W, Kesari S, Elledge SJ. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). Nature Biotechnology. 31: 331-4. PMID 23503679 DOI: 10.1038/nbt.2539  1
2013 Mali P, Aach J, Lee JH, Levner D, Nip L, Church GM. Barcoding cells using cell-surface programmable DNA-binding domains. Nature Methods. 10: 403-6. PMID 23503053 DOI: 10.1038/nmeth.2407  0.96
2013 Larman HB, Laserson U, Querol L, Verhaeghen K, Solimini NL, Xu GJ, Klarenbeek PL, Church GM, Hafler DA, Plenge RM, Nigrovic PA, De Jager PL, Weets I, Martens GA, O'Connor KC, et al. PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. Journal of Autoimmunity. 43: 1-9. PMID 23497938 DOI: 10.1016/j.jaut.2013.01.013  0.48
2013 Alivisatos AP, Chun M, Church GM, Deisseroth K, Donoghue JP, Greenspan RJ, McEuen PL, Roukes ML, Sejnowski TJ, Weiss PS, Yuste R. Neuroscience. The brain activity map. Science (New York, N.Y.). 339: 1284-5. PMID 23470729 DOI: 10.1126/science.1236939  1
2013 DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM. Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Research. 41: 4336-43. PMID 23460208 DOI: 10.1093/nar/gkt135  0.96
2013 Rockwell G, Guido NJ, Church GM. Redirector: designing cell factories by reconstructing the metabolic objective. Plos Computational Biology. 9: e1002882. PMID 23341769 DOI: 10.1371/journal.pcbi.1002882  1
2013 Church GM. Reading and writing omes. Molecular Systems Biology. 9: 642. PMID 23340848 DOI: 10.1038/msb.2012.75  0.01
2013 Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. RNA-guided human genome engineering via Cas9. Science (New York, N.Y.). 339: 823-6. PMID 23287722 DOI: 10.1126/science.1232033  0.96
2013 Wang HH, Mee MT, Church GM. Applications of Engineered Synthetic Ecosystems Synthetic Biology. 317-325. DOI: 10.1016/B978-0-12-394430-6.00017-0  1
2012 Eroshenko N, Kosuri S, Marblestone AH, Conway N, Church GM. Gene Assembly from Chip-Synthesized Oligonucleotides. Current Protocols in Chemical Biology. 2012. PMID 25077042 DOI: 10.1002/9780470559277.ch110190  1
2012 Chou MF, Prisic S, Lubner JM, Church GM, Husson RN, Schwartz D. Using bacteria to determine protein kinase specificity and predict target substrates. Plos One. 7: e52747. PMID 23300758 DOI: 10.1371/journal.pone.0052747  0.6
2012 Lin C, Jungmann R, Leifer AM, Li C, Levner D, Church GM, Shih WM, Yin P. Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA. Nature Chemistry. 4: 832-9. PMID 23000997 DOI: 10.1038/nchem.1451  0.76
2012 Mosberg JA, Gregg CJ, Lajoie MJ, Wang HH, Church GM. Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases. Plos One. 7: e44638. PMID 22957093 DOI: 10.1371/journal.pone.0044638  1
2012 Juhas M, Eberl L, Church GM. Essential genes as antimicrobial targets and cornerstones of synthetic biology. Trends in Biotechnology. 30: 601-7. PMID 22951051 DOI: 10.1016/j.tibtech.2012.08.002  0.08
2012 Zamft BM, Marblestone AH, Kording K, Schmidt D, Martin-Alarcon D, Tyo K, Boyden ES, Church G. Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencing. Plos One. 7: e43876. PMID 22928047 DOI: 10.1371/journal.pone.0043876  1
2012 Lajoie MJ, Gregg CJ, Mosberg JA, Washington GC, Church GM. Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering. Nucleic Acids Research. 40: e170. PMID 22904085 DOI: 10.1093/nar/gks751  1
2012 Church GM, Gao Y, Kosuri S. Next-generation digital information storage in DNA. Science (New York, N.Y.). 337: 1628. PMID 22903519 DOI: 10.1126/science.1226355  1
2012 Dreyfuss JM, Levner D, Galagan JE, Church GM, Ramoni MF. How accurate can genetic predictions be? Bmc Genomics. 13: 340. PMID 22827772 DOI: 10.1186/1471-2164-13-340  0.52
2012 Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, ... ... Church GM, et al. A public resource facilitating clinical use of genomes. Proceedings of the National Academy of Sciences of the United States of America. 109: 11920-7. PMID 22797899 DOI: 10.1073/pnas.1201904109  0.96
2012 Peters BA, Kermani BG, Sparks AB, Alferov O, Hong P, Alexeev A, Jiang Y, Dahl F, Tang YT, Haas J, Robasky K, Zaranek AW, Lee JH, Ball MP, Peterson JE, ... ... Church GM, et al. Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells. Nature. 487: 190-5. PMID 22785314 DOI: 10.1038/nature11236  0.88
2012 Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM. Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Research. 40: e117. PMID 22740649 DOI: 10.1093/nar/gks624  0.84
2012 Wang HH, Huang PY, Xu G, Haas W, Marblestone A, Li J, Gygi SP, Forster AC, Jewett MC, Church GM. Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multienzyme catalysis. Acs Synthetic Biology. 1: 43-52. PMID 22737598 DOI: 10.1021/sb3000029  1
2012 Alivisatos AP, Chun M, Church GM, Greenspan RJ, Roukes ML, Yuste R. The brain activity map project and the challenge of functional connectomics. Neuron. 74: 970-4. PMID 22726828 DOI: 10.1016/j.neuron.2012.06.006  1
2012 Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, Dewerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, ... ... Church GM, et al. A BioBrick compatible strategy for genetic modification of plants. Journal of Biological Engineering. 6: 8. PMID 22716313 DOI: 10.1186/1754-1611-6-8  1
2012 Carr PA, Wang HH, Sterling B, Isaacs FJ, Lajoie MJ, Xu G, Church GM, Jacobson JM. Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection. Nucleic Acids Research. 40: e132. PMID 22638574 DOI: 10.1093/nar/gks455  1
2012 Rios X, Briggs AW, Christodoulou D, Gorham JM, Seidman JG, Church GM. Stable gene targeting in human cells using single-strand oligonucleotides with modified bases. Plos One. 7: e36697. PMID 22615794 DOI: 10.1371/journal.pone.0036697  0.64
2012 Alon S, Mor E, Vigneault F, Church GM, Locatelli F, Galeano F, Gallo A, Shomron N, Eisenberg E. Systematic identification of edited microRNAs in the human brain. Genome Research. 22: 1533-40. PMID 22499667 DOI: 10.1101/gr.131573.111  0.36
2012 Wang HH, Kim H, Cong L, Jeong J, Bang D, Church GM. Genome-scale promoter engineering by coselection MAGE. Nature Methods. 9: 591-3. PMID 22484848 DOI: 10.1038/nmeth.1971  1
2012 Vigneault F, Ter-Ovanesyan D, Alon S, Eminaga S, C Christodoulou D, Seidman JG, Eisenberg E, M Church G. High-throughput multiplex sequencing of miRNA. Current Protocols in Human Genetics. Unit 11.12.1-10. PMID 22470142 DOI: 10.1002/0471142905.hg1112s73  1
2012 Thakuria JV, Zaranek AW, Church GM, Berry GT. Back to the future: from genome to metabolome. Human Mutation. 33: 809-12. PMID 22431014 DOI: 10.1002/humu.22073  0.72
2012 Gianoulis TA, Griffin MA, Spakowicz DJ, Dunican BF, Alpha CJ, Sboner A, Sismour AM, Kodira C, Egholm M, Church GM, Gerstein MB, Strobel SA. Genomic analysis of the hydrocarbon-producing, cellulolytic, endophytic fungus Ascocoryne sarcoides. Plos Genetics. 8: e1002558. PMID 22396667 DOI: 10.1371/journal.pgen.1002558  0.24
2012 Douglas SM, Bachelet I, Church GM. A logic-gated nanorobot for targeted transport of molecular payloads. Science (New York, N.Y.). 335: 831-4. PMID 22344439 DOI: 10.1126/science.1214081  0.76
2012 Ji J, Ng SH, Sharma V, Neculai D, Hussein S, Sam M, Trinh Q, Church GM, McPherson JD, Nagy A, Batada NN. Elevated coding mutation rate during the reprogramming of human somatic cells into induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 30: 435-40. PMID 22162363 DOI: 10.1002/stem.1011  0.24
2012 Church GM, Gryan G, Lakey N, Kieffer-Higgins S, Mintz L, Temple M, Jaehn L, Ghazizadeh H, Robison K, Rubenfield M, Richterich P. Automated Multiplex Sequencing Automated Dna Sequencing and Analysis. 11-16. DOI: 10.1016/B978-0-08-092639-1.50006-X  0.8
2011 Carmi S, Church GM, Levanon EY. Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution. Nature Communications. 2: 519. PMID 22044998 DOI: 10.1038/ncomms1525  0.6
2011 Umbarger MA, Toro E, Wright MA, Porreca GJ, Baù D, Hong SH, Fero MJ, Zhu LJ, Marti-Renom MA, McAdams HH, Shapiro L, Dekker J, Church GM. The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation. Molecular Cell. 44: 252-64. PMID 22017872 DOI: 10.1016/j.molcel.2011.09.010  0.96
2011 Quan SF, Shaw PJ, Naidoo N, Haeggström E, Krueger JM, Church GM. Panel discussion: can there be a biomarker for sleepiness? Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 7: S45-8. PMID 22003333 DOI: 10.5664/JCSM.1364  0.04
2011 Church GM. New technologies for integrating genomic, environmental and trait data. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 7: S43-4. PMID 22003332 DOI: 10.5664/JCSM.1362  0.01
2011 Shendure JA, Porreca GJ, Church GM, Gardner AF, Hendrickson CL, Kieleczawa J, Slatko BE. Overview of DNA sequencing strategies. Current Protocols in Molecular Biology. Unit7.1. PMID 21987056 DOI: 10.1002/0471142727.mb0701s96  0.96
2011 Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, ... ... Church GM, et al. Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. Plos Genetics. 7: e1002280. PMID 21935354 DOI: 10.1371/journal.pgen.1002280  0.72
2011 Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, ... Church GM, et al. Precise manipulation of chromosomes in vivo enables genome-wide codon replacement. Science (New York, N.Y.). 333: 348-53. PMID 21764749 DOI: 10.1126/science.1205822  1
2011 Alon S, Vigneault F, Eminaga S, Christodoulou DC, Seidman JG, Church GM, Eisenberg E. Barcoding bias in high-throughput multiplex sequencing of miRNA. Genome Research. 21: 1506-11. PMID 21750102 DOI: 10.1101/gr.121715.111  1
2011 Larman HB, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, Leproust EM, Solimini NL, Elledge SJ. Autoantigen discovery with a synthetic human peptidome. Nature Biotechnology. 29: 535-41. PMID 21602805 DOI: 10.1038/nbt.1856  0.68
2011 Wang HH, Church GM. Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering. Methods in Enzymology. 498: 409-26. PMID 21601688 DOI: 10.1016/B978-0-12-385120-8.00018-8  1
2011 Robertson DE, Jacobson SA, Morgan F, Berry D, Church GM, Afeyan NB. A new dawn for industrial photosynthesis. Photosynthesis Research. 107: 269-77. PMID 21318462 DOI: 10.1007/s11120-011-9631-7  0.08
2011 Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nature Biotechnology. 29: 149-53. PMID 21248753 DOI: 10.1038/nbt.1775  1
2011 Tolonen AC, Haas W, Chilaka AC, Aach J, Gygi SP, Church GM. Proteome-wide systems analysis of a cellulosic biofuel-producing microbe. Molecular Systems Biology. 7: 461. PMID 21245846 DOI: 10.1038/msb.2010.116  1
2011 Nelson FK, Snyder M, Gardner AF, Hendrickson CL, Shendure JA, Porreca GJ, Church GM, Ausubel FM, Ju J, Kieleczawa J, Slatko BE. Introduction and historical overview of DNA sequencing Current Protocols in Molecular Biology. DOI: 10.1002/0471142727.mb0700s96  1
2010 Shee K, Strong M, Guido NJ, Lue RA, Church GM, Viel A. Research, collaboration, and open science using web 2.0. Journal of Microbiology & Biology Education. 11: 130-4. PMID 23653712 DOI: 10.1128/jmbe.v11i2.219  1
2010 Sommer MO, Church GM, Dantas G. The human microbiome harbors a diverse reservoir of antibiotic resistance genes. Virulence. 1: 299-303. PMID 21178459 DOI: 10.4161/viru.1.4.12010  0.6
2010 Matzas M, Stähler PF, Kefer N, Siebelt N, Boisguérin V, Leonard JT, Keller A, Stähler CF, Häberle P, Gharizadeh B, Babrzadeh F, Church GM. High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing. Nature Biotechnology. 28: 1291-4. PMID 21113166 DOI: 10.1038/nbt.1710  0.08
2010 Kosuri S, Eroshenko N, Leproust EM, Super M, Way J, Li JB, Church GM. Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips. Nature Biotechnology. 28: 1295-9. PMID 21113165 DOI: 10.1038/nbt.1716  1
2010 Mosberg JA, Lajoie MJ, Church GM. Lambda red recombineering in Escherichia coli occurs through a fully single-stranded intermediate. Genetics. 186: 791-9. PMID 20813883 DOI: 10.1534/genetics.110.120782  1
2010 Schwartz D, Church GM. Collection and motif-based prediction of phosphorylation sites in human viruses. Science Signaling. 3: rs2. PMID 20807955 DOI: 10.1126/scisignal.2001099  0.6
2010 Loh YH, Hartung O, Li H, Guo C, Sahalie JM, Manos PD, Urbach A, Heffner GC, Grskovic M, Vigneault F, Lensch MW, Park IH, Agarwal S, Church GM, Collins JJ, et al. Reprogramming of T cells from human peripheral blood. Cell Stem Cell. 7: 15-9. PMID 20621044 DOI: 10.1016/j.stem.2010.06.004  1
2010 Zaranek AW, Levanon EY, Zecharia T, Clegg T, Church GM. A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing. Plos Genetics. 6: e1000954. PMID 20531933 DOI: 10.1371/journal.pgen.1000954  0.72
2010 Ashley EA, Butte AJ, Wheeler MT, Chen R, Klein TE, Dewey FE, Dudley JT, Ormond KE, Pavlovic A, Morgan AA, Pushkarev D, Neff NF, Hudgins L, Gong L, Hodges LM, ... ... Church GM, et al. Clinical assessment incorporating a personal genome. Lancet (London, England). 375: 1525-35. PMID 20435227 DOI: 10.1016/S0140-6736(10)60452-7  1
2010 Sommer MO, Church GM, Dantas G. A functional metagenomic approach for expanding the synthetic biology toolbox for biomass conversion. Molecular Systems Biology. 6: 360. PMID 20393580 DOI: 10.1038/msb.2010.16  0.6
2010 Lunshof JE, Bobe J, Aach J, Angrist M, Thakuria JV, Vorhaus DB, Hoehe MR, Church GM. Personal genomes in progress: from the human genome project to the personal genome project. Dialogues in Clinical Neuroscience. 12: 47-60. PMID 20373666  1
2010 Prisic S, Dankwa S, Schwartz D, Chou MF, Locasale JW, Kang CM, Bemis G, Church GM, Steen H, Husson RN. Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 107: 7521-6. PMID 20368441 DOI: 10.1073/pnas.0913482107  0.6
2010 Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, Kermani BG, Carnevali P, Nazarenko I, Nilsen GB, Yeung G, Dahl F, Fernandez A, Staker B, Pant KP, Baccash J, ... ... Church GM, et al. Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays. Science (New York, N.Y.). 327: 78-81. PMID 19892942 DOI: 10.1126/science.1181498  0.84
2010 Sullivan GJ, Hay DC, Park IH, Fletcher J, Hannoun Z, Payne CM, Dalgetty D, Black JR, Ross JA, Samuel K, Wang G, Daley GQ, Lee JH, Church GM, Forbes SJ, et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology (Baltimore, Md.). 51: 329-35. PMID 19877180 DOI: 10.1002/hep.23335  0.88
2010 Lunshof JE, Bobe J, Aach J, Angrist M, Thakuria JV, Vorhaus DB, Hoehe MR, Church GM. Personal genomes in progress: From the human genome project to the Personal Genome Project | Avances en el genoma personal: Desde el Proyecto Genoma Humano al Proyecto Genoma Personal Dialogues in Clinical Neuroscience. 12: 44-57.  1
2009 Carr PA, Church GM. Genome engineering. Nature Biotechnology. 27: 1151-62. PMID 20010598 DOI: 10.1038/nbt.1590  0.68
2009 Lee JH, Park IH, Gao Y, Li JB, Li Z, Daley GQ, Zhang K, Church GM. A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells. Plos Genetics. 5: e1000718. PMID 19911041 DOI: 10.1371/journal.pgen.1000718  1
2009 Fuller CW, Middendorf LR, Benner SA, Church GM, Harris T, Huang X, Jovanovich SB, Nelson JR, Schloss JA, Schwartz DC, Vezenov DV. The challenges of sequencing by synthesis. Nature Biotechnology. 27: 1013-23. PMID 19898456 DOI: 10.1038/nbt.1585  1
2009 Tolonen AC, Chilaka AC, Church GM. Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367. Molecular Microbiology. 74: 1300-13. PMID 19775243 DOI: 10.1111/j.1365-2958.2009.06890.x  1
2009 Barak M, Levanon EY, Eisenberg E, Paz N, Rechavi G, Church GM, Mehr R. Evidence for large diversity in the human transcriptome created by Alu RNA editing. Nucleic Acids Research. 37: 6905-15. PMID 19740767 DOI: 10.1093/nar/gkp729  1
2009 Sommer MO, Dantas G, Church GM. Functional characterization of the antibiotic resistance reservoir in the human microflora. Science (New York, N.Y.). 325: 1128-31. PMID 19713526 DOI: 10.1126/science.1176950  0.6
2009 Lun DS, Rockwell G, Guido NJ, Baym M, Kelner JA, Berger B, Galagan JE, Church GM. Large-scale identification of genetic design strategies using local search. Molecular Systems Biology. 5: 296. PMID 19690565 DOI: 10.1038/msb.2009.57  1
2009 Wang HH, Isaacs FJ, Carr PA, Sun ZZ, Xu G, Forest CR, Church GM. Programming cells by multiplex genome engineering and accelerated evolution. Nature. 460: 894-8. PMID 19633652 DOI: 10.1038/nature08187  1
2009 Zhang K, Li JB, Gao Y, Egli D, Xie B, Deng J, Li Z, Lee JH, Aach J, Leproust EM, Eggan K, Church GM. Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human. Nature Methods. 6: 613-8. PMID 19620972 DOI: 10.1038/nmeth.1357  1
2009 Khoury MJ, McBride CM, Schully SD, Ioannidis JP, Feero WG, Janssens AC, Gwinn M, Simons-Morton DG, Bernhardt JM, Cargill M, Chanock SJ, Church GM, Coates RJ, Collins FS, Croyle RT, et al. The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 11: 559-67. PMID 19617843 DOI: 10.1097/GIM.0b013e3181b13a6c  1
2009 Kim JI, Ju YS, Park H, Kim S, Lee S, Yi JH, Mudge J, Miller NA, Hong D, Bell CJ, Kim HS, Chung IS, Lee WC, Lee JS, Seo SH, ... ... Church GM, et al. A highly annotated whole-genome sequence of a Korean individual. Nature. 460: 1011-5. PMID 19587683 DOI: 10.1038/nature08211  0.96
2009 Douglas SM, Marblestone AH, Teerapittayanon S, Vazquez A, Church GM, Shih WM. Rapid prototyping of 3D DNA-origami shapes with caDNAno. Nucleic Acids Research. 37: 5001-6. PMID 19531737 DOI: 10.1093/nar/gkp436  0.76
2009 Li JB, Gao Y, Aach J, Zhang K, Kryukov GV, Xie B, Ahlford A, Yoon JK, Rosenbaum AM, Zaranek AW, LeProust E, Sunyaev SR, Church GM. Multiplex padlock targeted sequencing reveals human hypermutable CpG variations. Genome Research. 19: 1606-15. PMID 19525355 DOI: 10.1101/gr.092213.109  1
2009 Li JB, Levanon EY, Yoon JK, Aach J, Xie B, Leproust E, Zhang K, Gao Y, Church GM. Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science (New York, N.Y.). 324: 1210-3. PMID 19478186 DOI: 10.1126/science.1170995  1
2009 Ball MP, Li JB, Gao Y, Lee JH, LeProust EM, Park IH, Xie B, Daley GQ, Church GM. Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nature Biotechnology. 27: 361-8. PMID 19329998 DOI: 10.1038/nbt.1533  1
2009 Sandgren A, Strong M, Muthukrishnan P, Weiner BK, Church GM, Murray MB. Tuberculosis drug resistance mutation database. Plos Medicine. 6: e2. PMID 19209951 DOI: 10.1371/journal.pmed.1000002  1
2009 de Magalhães JP, Curado J, Church GM. Meta-analysis of age-related gene expression profiles identifies common signatures of aging. Bioinformatics (Oxford, England). 25: 875-81. PMID 19189975 DOI: 10.1093/bioinformatics/btp073  1
2009 de Magalhães JP, Budovsky A, Lehmann G, Costa J, Li Y, Fraifeld V, Church GM. The Human Ageing Genomic Resources: online databases and tools for biogerontologists. Aging Cell. 8: 65-72. PMID 18986374 DOI: 10.1111/j.1474-9726.2008.00442.x  1
2009 Schwartz D, Chou MF, Church GM. Predicting protein post-translational modifications using meta-analysis of proteome scale data sets. Molecular & Cellular Proteomics : McP. 8: 365-79. PMID 18974045 DOI: 10.1074/mcp.M800332-MCP200  1
2009 Douglas SM, Dietz H, Liedl T, Högberg B, Graf F, Marblestone AH, Teerapittayanon S, Vazquez A, Church GM, Shih WM. Design and self-assembly of DNA into nanoscale 3D shapes Siggraph 2009: Talks, Siggraph '09 1
2008 Zaranek AW, Clegg T, Vandewege W, Church GM. Free Factories: Unified Infrastructure for Data Intensive Web Services. Proceedings of the Usenix ... Annual Technical Conference. Usenix Technical Conference. 2008: 391-404. PMID 20514356  0.72
2008 Vigneault F, Sismour AM, Church GM. Efficient microRNA capture and bar-coding via enzymatic oligonucleotide adenylation. Nature Methods. 5: 777-9. PMID 19160512 DOI: 10.1038/nmeth.1244  1
2008 Isenbarger TA, Carr CE, Johnson SS, Finney M, Church GM, Gilbert W, Zuber MT, Ruvkun G. The most conserved genome segments for life detection on Earth and other planets. Origins of Life and Evolution of the Biosphere : the Journal of the International Society For the Study of the Origin of Life. 38: 517-33. PMID 18853276 DOI: 10.1007/s11084-008-9148-z  1
2008 Snitkin ES, Dudley AM, Janse DM, Wong K, Church GM, Segrè D. Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions. Genome Biology. 9: R140. PMID 18808699 DOI: 10.1186/gb-2008-9-9-r140  0.92
2008 Lunshof JE, Chadwick R, Church GM. Hippocrates revisited? Old ideals and new realities. Genomic Medicine. 2: 1-3. PMID 18716915 DOI: 10.1007/s11568-008-9020-2  1
2008 Dantas G, Sommer MO, Oluwasegun RD, Church GM. Bacteria subsisting on antibiotics. Science (New York, N.Y.). 320: 100-3. PMID 18388292 DOI: 10.1126/science.1155157  0.6
2008 Lunshof JE, Chadwick R, Vorhaus DB, Church GM. From genetic privacy to open consent. Nature Reviews. Genetics. 9: 406-11. PMID 18379574 DOI: 10.1038/nrg2360  1
2008 Shendure JA, Porreca GJ, Church GM. Overview of DNA sequencing strategies. Current Protocols in Molecular Biology. Unit 7.1. PMID 18231983 DOI: 10.1002/0471142727.mb0701s81  0.96
2008 Bang D, Church GM. Gene synthesis by circular assembly amplification. Nature Methods. 5: 37-9. PMID 18037891 DOI: 10.1038/nmeth1136  1
2008 Church GM, Porreca GJ, Terry RC, Lares M. High-speed imaging for DNA sequencing Biophotonics International. 15: 34-36.  1
2008 Forest CR, Rosenbaum AM, Church GM. DNA sequencing by ligation on surfacebound beads in a microchannel environment 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 634-636.  1
2007 Kettler GC, Martiny AC, Huang K, Zucker J, Coleman ML, Rodrigue S, Chen F, Lapidus A, Ferriera S, Johnson J, Steglich C, Church GM, Richardson P, Chisholm SW. Patterns and implications of gene gain and loss in the evolution of Prochlorococcus. Plos Genetics. 3: e231. PMID 18159947 DOI: 10.1371/journal.pgen.0030231  1
2007 Porreca GJ, Zhang K, Li JB, Xie B, Austin D, Vassallo SL, LeProust EM, Peck BJ, Emig CJ, Dahl F, Gao Y, Church GM, Shendure J. Multiplex amplification of large sets of human exons. Nature Methods. 4: 931-6. PMID 17934468 DOI: 10.1038/nmeth1110  1
2007 Lindell D, Jaffe JD, Coleman ML, Futschik ME, Axmann IM, Rector T, Kettler G, Sullivan MB, Steen R, Hess WR, Church GM, Chisholm SW. Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution. Nature. 449: 83-6. PMID 17805294 DOI: 10.1038/nature06130  0.8
2007 de Magalhães JP, Sedivy JM, Finch CE, Austad SN, Church GM. A proposal to sequence genomes of unique interest for research on aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 583-4. PMID 17595413  1
2007 Wright MA, Kharchenko P, Church GM, Segrè D. Chromosomal periodicity of evolutionarily conserved gene pairs. Proceedings of the National Academy of Sciences of the United States of America. 104: 10559-64. PMID 17563360 DOI: 10.1073/pnas.0610776104  1
2007 Kim JB, Porreca GJ, Song L, Greenway SC, Gorham JM, Church GM, Seidman CE, Seidman JG. Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy. Science (New York, N.Y.). 316: 1481-4. PMID 17556586 DOI: 10.1126/science.1137325  0.96
2007 de Magalhães JP, Church GM. Analyses of human-chimpanzee orthologous gene pairs to explore evolutionary hypotheses of aging Mechanisms of Ageing and Development. 128: 355-364. PMID 17459455 DOI: 10.1016/j.mad.2007.03.004  1
2007 De Magalhães JP, Costa J, Church GM. An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 62: 149-160. PMID 17339640  1
2007 Forster AC, Church GM. Synthetic biology projects in vitro Genome Research. 17: 1-6. PMID 17151344 DOI: 10.1101/gr.5776007  1
2006 Porreca GJ, Shendure J, Church GM. Polony DNA sequencing. Current Protocols in Molecular Biology. Unit 7.8. PMID 18265387 DOI: 10.1002/0471142727.mb0708s76  0.96
2006 Yang A, Zhu Z, Kapranov P, McKeon F, Church GM, Gingeras TR, Struhl K. Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. Molecular Cell. 24: 593-602. PMID 17188034 DOI: 10.1016/j.molcel.2006.10.018  0.96
2006 Reppas NB, Wade JT, Church GM, Struhl K. The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting. Molecular Cell. 24: 747-57. PMID 17157257 DOI: 10.1016/j.molcel.2006.10.030  0.84
2006 Tolonen AC, Aach J, Lindell D, Johnson ZI, Rector T, Steen R, Church GM, Chisholm SW. Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability. Molecular Systems Biology. 2: 53. PMID 17016519 DOI: 10.1038/msb4100087  1
2006 Derti A, Roth FP, Church GM, Wu CT. Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants. Nature Genetics. 38: 1216-20. PMID 16998490 DOI: 10.1038/ng1888  0.96
2006 Lee SI, Pe'er D, Dudley AM, Church GM, Koller D. Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification. Proceedings of the National Academy of Sciences of the United States of America. 103: 14062-7. PMID 16968785 DOI: 10.1073/pnas.0601852103  1
2006 Forster AC, Church GM. Towards synthesis of a minimal cell Molecular Systems Biology [Electronic Resource].. 2: 45. PMID 16924266 DOI: 10.1038/msb4100090  1
2006 Jaffe JD, Mani DR, Leptos KC, Church GM, Gillette MA, Carr SA. PEPPeR, a platform for experimental proteomic pattern recognition. Molecular & Cellular Proteomics : McP. 5: 1927-41. PMID 16857664 DOI: 10.1074/mcp.M600222-MCP200  0.8
2006 Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, ... ... Church GM, et al. A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies. Nature Biotechnology. 24: 832-40. PMID 16823376 DOI: 10.1038/nbt1217  1
2006 Zhang K, Martiny AC, Reppas NB, Barry KW, Malek J, Chisholm SW, Church GM. Sequencing genomes from single cells by polymerase cloning. Nature Biotechnology. 24: 680-6. PMID 16732271 DOI: 10.1038/nbt1214  0.88
2006 Kharchenko P, Chen L, Freund Y, Vitkup D, Church GM. Identifying metabolic enzymes with multiple types of association evidence. Bmc Bioinformatics. 7: 177. PMID 16571130 DOI: 10.1186/1471-2105-7-177  1
2006 Zhang K, Zhu J, Shendure J, Porreca GJ, Aach JD, Mitra RD, Church GM. Long-range polony haplotyping of individual human chromosome molecules. Nature Genetics. 38: 382-7. PMID 16493423 DOI: 10.1038/ng1741  0.96
2006 Estrada B, Choe SE, Gisselbrecht SS, Michaud S, Raj L, Busser BW, Halfon MS, Church GM, Michelson AM. An integrated strategy for analyzing the unique developmental programs of different myoblast subtypes. Plos Genetics. 2: e16. PMID 16482229 DOI: 10.1371/journal.pgen.0020016  1
2006 Leptos KC, Sarracino DA, Jaffe JD, Krastins B, Church GM. MapQuant: open-source software for large-scale protein quantification. Proteomics. 6: 1770-82. PMID 16470651 DOI: 10.1002/pmic.200500201  0.8
2006 Church GM. Genomes for all Scientific American.. 294: 46-54. PMID 16468433  1
2006 Magalhães JPD, Church GM. Cells discover fire: Employing reactive oxygen species in development and consequences for aging Experimental Gerontology. 41: 1-10. PMID 16226003 DOI: 10.1016/j.exger.2005.09.002  1
2005 Dudley AM, Janse DM, Tanay A, Shamir R, Church GM. A global view of pleiotropy and phenotypically derived gene function in yeast. Molecular Systems Biology. 1: 2005.0001. PMID 16729036 DOI: 10.1038/msb4100004  1
2005 Wade JT, Reppas NB, Church GM, Struhl K. Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites. Genes & Development. 19: 2619-30. PMID 16264194 DOI: 10.1101/gad.1355605  0.84
2005 Lindell D, Jaffe JD, Johnson ZI, Church GM, Chisholm SW. Photosynthesis genes in marine viruses yield proteins during host infection. Nature. 438: 86-9. PMID 16222247 DOI: 10.1038/nature04111  0.8
2005 Petti AA, Church GM. A network of transcriptionally coordinated functional modules in Saccharomyces cerevisiae. Genome Research. 15: 1298-306. PMID 16109970 DOI: 10.1101/gr.3847105  0.76
2005 Shendure J, Porreca GJ, Reppas NB, Lin X, McCutcheon JP, Rosenbaum AM, Wang MD, Zhang K, Mitra RD, Church GM. Accurate multiplex polony sequencing of an evolved bacterial genome. Science (New York, N.Y.). 309: 1728-32. PMID 16081699 DOI: 10.1126/science.1117389  0.96
2005 Zhu Z, Shendure J, Church GM. Discovering functional transcription-factor combinations in the human cell cycle. Genome Research. 15: 848-55. PMID 15930495 DOI: 10.1101/gr.3394405  0.96
2005 Tompa M, Li N, Bailey TL, Church GM, De Moor B, Eskin E, Favorov AV, Frith MC, Fu Y, Kent WJ, Makeev VJ, Mironov AA, Noble WS, Pavesi G, Pesole G, et al. Assessing computational tools for the discovery of transcription factor binding sites. Nature Biotechnology. 23: 137-44. PMID 15637633 DOI: 10.1038/nbt1053  0.96
2005 Segrè D, Deluna A, Church GM, Kishony R. Modular epistasis in yeast metabolism. Nature Genetics. 37: 77-83. PMID 15592468 DOI: 10.1038/ng1489  1
2004 Jaffe JD, Stange-Thomann N, Smith C, DeCaprio D, Fisher S, Butler J, Calvo S, Elkins T, FitzGerald MG, Hafez N, Kodira CD, Major J, Wang S, Wilkinson J, Nicol R, ... ... Church GM, et al. The complete genome and proteome of Mycoplasma mobile. Genome Research. 14: 1447-61. PMID 15289470 DOI: 10.1101/gr.2674004  0.8
2004 Grad YH, Roth FP, Halfon MS, Church GM. Prediction of similarly acting cis-regulatory modules by subsequence profiling and comparative genomics in Drosophila melanogaster and D.pseudoobscura. Bioinformatics (Oxford, England). 20: 2738-50. PMID 15145800 DOI: 10.1093/bioinformatics/bth320  0.96
2004 Shendure J, Mitra RD, Varma C, Church GM. Advanced sequencing technologies: methods and goals. Nature Reviews. Genetics. 5: 335-44. PMID 15143316 DOI: 10.1038/nrg1325  0.96
2004 Janse DM, Crosas B, Finley D, Church GM. Localization to the proteasome is sufficient for degradation. The Journal of Biological Chemistry. 279: 21415-20. PMID 15039430 DOI: 10.1074/jbc.M402954200  0.92
2004 Bulyk ML, McGuire AM, Masuda N, Church GM. A motif co-occurrence approach for genome-wide prediction of transcription-factor-binding sites in Escherichia coli. Genome Research. 14: 201-8. PMID 14762058 DOI: 10.1101/gr.1448004  0.92
2004 Jaffe JD, Berg HC, Church GM. Proteogenomic mapping as a complementary method to perform genome annotation. Proteomics. 4: 59-77. PMID 14730672 DOI: 10.1002/pmic.200300511  0.8
2004 Lelandais G, Le Crom S, Devaux F, Vialette S, Church GM, Jacq C, Marc P. yMGV: a cross-species expression data mining tool. Nucleic Acids Research. 32: D323-5. PMID 14681424 DOI: 10.1093/nar/gkh135  0.68
2003 Segrè D, Zucker J, Katz J, Lin X, D'haeseleer P, Rindone WP, Kharchenko P, Nguyen DH, Wright MA, Church GM. From annotated genomes to metabolic flux models and kinetic parameter fitting. Omics : a Journal of Integrative Biology. 7: 301-16. PMID 14583118 DOI: 10.1089/153623103322452413  1
2003 Zhu J, Shendure J, Mitra RD, Church GM. Single molecule profiling of alternative pre-mRNA splicing. Science (New York, N.Y.). 301: 836-8. PMID 12907803 DOI: 10.1126/science.1085792  0.96
2003 Mitra RD, Shendure J, Olejnik J, Edyta-Krzymanska-Olejnik, Church GM. Fluorescent in situ sequencing on polymerase colonies. Analytical Biochemistry. 320: 55-65. PMID 12895469  0.96
2003 King OD, Lee JC, Dudley AM, Janse DM, Church GM, Roth FP. Predicting phenotype from patterns of annotation. Bioinformatics (Oxford, England). 19: i183-9. PMID 12855456  0.96
2003 Selinger DW, Wright MA, Church GM. On the complete determination of biological systems. Trends in Biotechnology. 21: 251-4. PMID 12788544 DOI: 10.1016/S0167-7799(03)00113-6  0.64
2003 Mitra RD, Butty VL, Shendure J, Williams BR, Housman DE, Church GM. Digital genotyping and haplotyping with polymerase colonies. Proceedings of the National Academy of Sciences of the United States of America. 100: 5926-31. PMID 12730373 DOI: 10.1073/pnas.0936399100  0.96
2003 Selinger DW, Saxena RM, Cheung KJ, Church GM, Rosenow C. Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation. Genome Research. 13: 216-23. PMID 12566399 DOI: 10.1101/gr.912603  0.64
2003 Cheung KJ, Badarinarayana V, Selinger DW, Janse D, Church GM. A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli. Genome Research. 13: 206-15. PMID 12566398 DOI: 10.1101/gr.401003  0.64
2002 Lee ML, Bulyk ML, Whitmore GA, Church GM. A statistical model for investigating binding probabilities of DNA nucleotide sequences using microarrays. Biometrics. 58: 981-8. PMID 12495153  0.72
2002 Segrè D, Vitkup D, Church GM. Analysis of optimality in natural and perturbed metabolic networks. Proceedings of the National Academy of Sciences of the United States of America. 99: 15112-7. PMID 12415116 DOI: 10.1073/pnas.232349399  0.92
2002 Shendure J, Church GM. Computational discovery of sense-antisense transcription in the human and mouse genomes. Genome Biology. 3: RESEARCH0044. PMID 12225583  0.96
2002 Zhu Z, Pilpel Y, Church GM. Computational identification of transcription factor binding sites via a transcription-factor-centric clustering (TFCC) algorithm. Journal of Molecular Biology. 318: 71-81. PMID 12054769 DOI: 10.1016/S0022-2836(02)00026-8  0.96
2002 Dudley AM, Aach J, Steffen MA, Church GM. Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range. Proceedings of the National Academy of Sciences of the United States of America. 99: 7554-9. PMID 12032321 DOI: 10.1073/pnas.112683499  1
2002 Bulyk ML, Johnson PL, Church GM. Nucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factors. Nucleic Acids Research. 30: 1255-61. PMID 11861919  0.72
2002 Weber G, Shendure J, Tanenbaum DM, Church GM, Meyerson M. Identification of foreign gene sequences by transcript filtering against the human genome. Nature Genetics. 30: 141-2. PMID 11788827 DOI: 10.1038/ng818  0.96
2001 Chen T, Jaffe JD, Church GM. Algorithms for identifying protein cross-links via tandem mass spectrometry. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 8: 571-83. PMID 11747613 DOI: 10.1089/106652701753307494  0.8
2001 Badarinarayana V, Estep PW, Shendure J, Edwards J, Tavazoie S, Lam F, Church GM. Selection analyses of insertional mutants using subgenic-resolution arrays. Nature Biotechnology. 19: 1060-5. PMID 11689852 DOI: 10.1038/nbt1101-1060  1
2001 Bulyk ML, Huang X, Choo Y, Church GM. Exploring the DNA-binding specificities of zinc fingers with DNA microarrays. Proceedings of the National Academy of Sciences of the United States of America. 98: 7158-63. PMID 11404456 DOI: 10.1073/pnas.111163698  1
2001 Aach J, Bulyk ML, Church GM, Comander J, Derti A, Shendure J. Computational comparison of two draft sequences of the human genome. Nature. 409: 856-9. PMID 11237010 DOI: 10.1038/35057055  1
2000 Selinger DW, Cheung KJ, Mei R, Johansson EM, Richmond CS, Blattner FR, Lockhart DJ, Church GM. RNA expression analysis using a 30 base pair resolution Escherichia coli genome array. Nature Biotechnology. 18: 1262-8. PMID 11101804 DOI: 10.1038/82367  1
2000 Goldmark JP, Fazzio TG, Estep PW, Church GM, Tsukiyama T. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell. 103: 423-33. PMID 11081629  1
2000 Cohen BA, Mitra RD, Hughes JD, Church GM. A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression. Nature Genetics. 26: 183-6. PMID 11017073 DOI: 10.1038/79896  1
2000 McGuire AM, Hughes JD, Church GM. Conservation of DNA regulatory motifs and discovery of new motifs in microbial genomes. Genome Research. 10: 744-57. PMID 10854408 DOI: 10.1101/gr.10.6.744  1
2000 Hughes JD, Estep PW, Tavazoie S, Church GM. Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae. Journal of Molecular Biology. 296: 1205-14. PMID 10698627 DOI: 10.1006/jmbi.2000.3519  1
1999 Tavazoie S, Hughes JD, Campbell MJ, Cho RJ, Church GM. Systematic determination of genetic network architecture. Nature Genetics. 22: 281-5. PMID 10391217 DOI: 10.1038/10343  1
1999 Bulyk ML, Gentalen E, Lockhart DJ, Church GM. Quantifying DNA-protein interactions by double-stranded DNA arrays. Nature Biotechnology. 17: 573-7. PMID 10385322 DOI: 10.1038/9878  1
1999 McGuire AM, De Wulf P, Church GM, Lin EC. A weight matrix for binding recognition by the redox-response regulator ArcA-P of Escherichia coli. Molecular Microbiology. 32: 219-21. PMID 10216875  1
1998 Robison K, McGuire AM, Church GM. A comprehensive library of DNA-binding site matrices for 55 proteins applied to the complete Escherichia coli K-12 genome. Journal of Molecular Biology. 284: 241-54. PMID 9813115 DOI: 10.1006/jmbi.1998.2160  1
1998 Roth FP, Hughes JD, Estep PW, Church GM. Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation. Nature Biotechnology. 16: 939-45. PMID 9788350 DOI: 10.1038/nbt1098-939  1
1998 Tavazoie S, Church GM. Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli. Nature Biotechnology. 16: 566-71. PMID 9624689 DOI: 10.1038/nbt0698-566  1
1996 Robison K, Gilbert W, Church GM. More haemophilus and Mycoplasma genes. Science (New York, N.Y.). 271: 1302b-3b. PMID 17820934 DOI: 10.1126/science.271.5253.1302b  1
1996 Robison K, Gilbert W, Church GM. More Haemophilus and Mycoplasma genes. Science (New York, N.Y.). 271: 1302-3; author reply. PMID 8638118  1
1994 Robison K, Gilbert W, Church GM. Large scale bacterial gene discovery by similarity search. Nature Genetics. 7: 205-14. PMID 7920643 DOI: 10.1038/ng0694-205  1
1985 Church GM, Ephrussi A, Gilbert W, Tonegawa S. Cell-type-specific contacts to immunoglobulin enhancers in nuclei. Nature. 313: 798-801. PMID 3919308 DOI: 10.1038/313798a0  1
1985 Ephrussi A, Church GM, Tonegawa S, Gilbert W. B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo. Science (New York, N.Y.). 227: 134-40. PMID 3917574  1
1985 Church GM, Gilbert W. The genomic sequencing technique. Progress in Clinical and Biological Research. 177: 17-21. PMID 2989835  1
1984 Church GM, Gilbert W. Genomic sequencing. Proceedings of the National Academy of Sciences of the United States of America. 81: 1991-5. PMID 6326095  1
1979 Church GM, Slonimski PP, Gilbert W. Pleiotropic mutations within two yeast mitochondrial cytochrome genes block mRNA processing. Cell. 18: 1209-15. PMID 229970  1
1978 Sussman JL, Holbrook SR, Warrant RW, Church GM, Kim SH. Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement. Journal of Molecular Biology. 123: 607-30. PMID 357742  0.96
1977 Holbrook SR, Sussman JL, Warrant RW, Church GM, Kim SH. RNA-ligant interactions. (I) Magnesium binding sites in yeast tRNAPhe. Nucleic Acids Research. 4: 2811-20. PMID 333395  0.96
1977 Church GM, Sussman JL, Kim SH. Secondary structural complementarity between DNA and proteins. Proceedings of the National Academy of Sciences of the United States of America. 74: 1458-62. PMID 266187  0.96
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