| Year |
Citation |
Score |
| 2019 |
Golden MP, Côté I, Green SM, Toklu HZ, Tüme N, Scarpace PJ, Yarrow JF. The Effects of Leptin and Estradiol Administration on Cancellous Bone Microarchitecture in Male Rats Medicine & Science in Sports & Exercise. 51: 755. DOI: 10.1249/01.Mss.0000562750.58750.53 |
0.364 |
|
| 2018 |
Côté I, Green SM, Yarrow JF, Conover CF, Toklu HZ, Morgan D, Carter CS, Tümer N, Scarpace PJ. Estradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in rats. Journal of Neuroendocrinology. e12646. PMID 30246441 DOI: 10.1111/Jne.12646 |
0.502 |
|
| 2018 |
Cote I, Toklu HZ, Green SM, Morgan D, Carter CS, Tumer N, Scarpace PJ. Limiting feeding to the active phase reduces blood pressure without the necessity of caloric reduction or fat mass loss. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30024775 DOI: 10.1152/Ajpregu.00076.2018 |
0.452 |
|
| 2018 |
Bruce EB, Sakarya Y, Kirichenko N, Toklu HZ, Sumners C, Morgan D, Tümer N, Scarpace PJ, Carter CS. ACE2 activator diminazene aceturate reduces adiposity but preserves lean mass in young and old rats. Experimental Gerontology. PMID 30006298 DOI: 10.1016/J.Exger.2018.07.008 |
0.553 |
|
| 2018 |
Scarpace P, Côté I, Green S, Morgan D, Carter C, Tümer N. ESTRADIOL AND LEPTIN OVEREXPRESSION HAVE INDEPENDENT MODES OF ACTION ON DECREASED FOOD INTAKE AND BODY WEIGHT IN MALES RATS Journal of Hypertension. 36: e84. DOI: 10.1097/01.Hjh.0000539206.85977.8D |
0.457 |
|
| 2017 |
Côté I, Green SM, Morgan D, Carter C, Tümer N, Scarpace PJ. Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reduction. Canadian Journal of Physiology and Pharmacology. PMID 29131966 DOI: 10.1139/Cjpp-2017-0440 |
0.415 |
|
| 2017 |
Cote I, Sakarya Y, Green SM, Morgan D, Carter CS, Tumer N, Scarpace PJ. iBAT sympathetic innervation is not required for body weight loss induced by central leptin delivery. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00219.2017. PMID 29089334 DOI: 10.1152/Ajpendo.00219.2017 |
0.486 |
|
| 2017 |
Côté I, Green SM, Toklu HZ, Morgan D, Carter CS, Tümer N, Scarpace PJ. Differential physiological responses to central leptin overexpression in male and female rats. Journal of Neuroendocrinology. PMID 29044801 DOI: 10.1111/Jne.12552 |
0.404 |
|
| 2017 |
Basgut B, Whidden MA, Kirichenko N, Woods M, Erdos B, Scarpace PJ, Tümer N. Effect of High-Salt Diet on Age-Related High Blood Pressure and Hypothalamic Redox Signaling. Pharmacology. 100: 105-114. PMID 28521325 DOI: 10.1159/000472259 |
0.351 |
|
| 2017 |
Scarpace P, Cote I, Toklu H, Tumer N. [Lb.02.29] Feeding Schedule Reduces Blood Pressure But Does Not Protect Against Diet-Induced Obesity In Rats Journal of Hypertension. 35. DOI: 10.1097/01.Hjh.0000523754.95393.4A |
0.47 |
|
| 2016 |
Côté I, Sakarya Y, Kirichenko N, Morgan D, Carter CS, Tümer N, Scarpace PJ. Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction. Canadian Journal of Physiology and Pharmacology. 1-9. PMID 28051332 DOI: 10.1139/Cjpp-2016-0290 |
0.408 |
|
| 2016 |
Toklu HZ, Scarpace PJ, Sakarya Y, Kirichenko N, Matheny M, Bruce EB, Carter CS, Morgan D, Tümer N. Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change STAT3 signalling or SIRT1/AMPK pathway. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. 1-9. PMID 28006433 DOI: 10.1139/Apnm-2016-0067 |
0.467 |
|
| 2016 |
Gocmez SS, Scarpace PJ, Whidden MA, Erdos B, Kirichenko N, Sakarya Y, Utkan T, Tumer N. Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries. Journal of Exercise Nutrition & Biochemistry. 20: 41-8. PMID 27298812 DOI: 10.20463/Jenb.2016.03.20.1.2 |
0.343 |
|
| 2016 |
Toklu HZ, Bruce EB, Sakarya Y, Carter CS, Morgan D, Matheny MK, Kirichenko N, Scarpace PJ, Tümer N. Anorexic response to rapamycin does not appear to involve a central mechanism. Clinical and Experimental Pharmacology & Physiology. PMID 27232670 DOI: 10.1111/1440-1681.12601 |
0.503 |
|
| 2016 |
Toklu HZ, Muller-Delp J, Sakaraya Y, Oktay S, Kirichenko N, Matheny M, Carter CS, Morgan D, Strehler KY, Tumer N, Scarpace PJ. High dietary fructose does not exacerbate the detrimental consequences of high fat diet on basilar artery function. Journal of Physiology and Pharmacology : An Official Journal of the Polish Physiological Society. 67: 205-16. PMID 27226180 |
0.343 |
|
| 2016 |
Gocmez SS, Gacar N, Utkan T, Gacar G, Scarpace PJ, Tumer N. Protective effects of resveratrol on aging-induced cognitive impairment in rats. Neurobiology of Learning and Memory. 131: 131-6. PMID 27040098 DOI: 10.1016/J.Nlm.2016.03.022 |
0.377 |
|
| 2016 |
Strehler KY, Matheny M, Kirichenko N, Sakarya Y, Bruce E, Toklu HZ, Carter CS, Morgan D, Tümer N, Scarpace PJ. Onset of leptin resistance shows temporal differences related to dose or pulsed treatment. European Journal of Pharmacology. PMID 27012992 DOI: 10.1016/J.Ejphar.2016.03.026 |
0.415 |
|
| 2016 |
Yarrow JF, Toklu HZ, Balaez A, Phillips EG, Otzel DM, Chen C, Wronski TJ, Aguirre JI, Sakarya Y, Tümer N, Scarpace PJ. Fructose consumption does not worsen bone deficits resulting from high-fat feeding in young male rats. Bone. PMID 26855373 DOI: 10.1016/J.Bone.2016.02.004 |
0.374 |
|
| 2015 |
Carter CS, Khamiss D, Matheny M, Toklu HZ, Kirichenko N, Strehler KY, Tümer N, Scarpace PJ, Morgan D. Rapamycin Versus Intermittent Feeding: Dissociable Effects on Physiological and Behavioral Outcomes When Initiated Early and Late in Life. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25617380 DOI: 10.1093/Gerona/Glu238 |
0.439 |
|
| 2015 |
Scarpace PJ, Matheny M, Strehler KY, Toklu HZ, Kirichenko N, Carter CS, Morgan D, Tümer N. Rapamycin Normalizes Serum Leptin by Alleviating Obesity and Reducing Leptin Synthesis in Aged Rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25617379 DOI: 10.1093/Gerona/Glu230 |
0.56 |
|
| 2015 |
Tumer N, Toklu HZ, Muller-Delp J, Sakarya Y, Oktay S, Matheny M, Kirichenko N, Carter C, Morgan D, Scarpace PJ. Pp.19.20: High Fat Plus Dietary Fructose Is Not More Deleterious Than A High Fat Diet On Cardiovascular Health Journal of Hypertension. 33. DOI: 10.1097/01.Hjh.0000468299.75276.Bb |
0.38 |
|
| 2014 |
Matheny M, Strehler KYE, King M, Tümer N, Scarpace PJ. Targeted leptin receptor blockade: Role of ventral tegmental area and nucleus of the solitary tract leptin receptors in body weight homeostasis Journal of Endocrinology. 222: 27-41. PMID 24920667 DOI: 10.1530/Joe-13-0455 |
0.485 |
|
| 2014 |
Tümer N, Toklu HZ, Muller-Delp JM, Oktay S, Ghosh P, Strang K, Delp MD, Scarpace PJ. The effects of aging on the functional and structural properties of the rat basilar artery. Physiological Reports. 2. PMID 24907295 DOI: 10.14814/Phy2.12031 |
0.347 |
|
| 2014 |
Toklu HZ, Kwon OS, Sakarya Y, Powers SK, Llinas K, Kirichenko N, Sollanek KJ, Wiggs MP, Smuder AJ, Talbert EE, Scarpace PJ, Tümer N. The effects of enalapril and losartan on mechanical ventilation-induced sympathoadrenal activation and oxidative stress in rats. The Journal of Surgical Research. 188: 510-6. PMID 24630519 DOI: 10.1016/J.Jss.2014.01.054 |
0.313 |
|
| 2013 |
Tümer N, Svetlov S, Whidden M, Kirichenko N, Prima V, Erdos B, Sherman A, Kobeissy F, Yezierski R, Scarpace PJ, Vierck C, Wang KK. Overpressure blast-wave induced brain injury elevates oxidative stress in the hypothalamus and catecholamine biosynthesis in the rat adrenal medulla. Neuroscience Letters. 544: 62-7. PMID 23570732 DOI: 10.1016/J.Neulet.2013.03.042 |
0.365 |
|
| 2013 |
Vasselli JR, Scarpace PJ, Harris RB, Banks WA. Dietary components in the development of leptin resistance. Advances in Nutrition (Bethesda, Md.). 4: 164-75. PMID 23493533 DOI: 10.3945/An.112.003152 |
0.507 |
|
| 2013 |
Scarpace PJ, Matheny M, Kirichenko N, Gao YX, Tümer N, Zhang Y. Leptin overexpression in VTA trans-activates the hypothalamus whereas prolonged leptin action in either region cross-desensitizes Neuropharmacology. 65: 90-100. PMID 22982569 DOI: 10.1016/J.Neuropharm.2012.09.005 |
0.47 |
|
| 2012 |
Scarpace ET, Matheny M, Strehler KY, Shapiro A, Cheng KY, Tümer N, Scarpace PJ. Simultaneous introduction of a novel high fat diet and wheel running induces anorexia. Physiology & Behavior. 105: 909-14. PMID 22115947 DOI: 10.1016/J.Physbeh.2011.11.011 |
0.469 |
|
| 2011 |
Andino LM, Ryder DJ, Shapiro A, Matheny MK, Zhang Y, Judge MK, Cheng KY, Tümer N, Scarpace PJ. POMC overexpression in the ventral tegmental area ameliorates dietary obesity. The Journal of Endocrinology. 210: 199-207. PMID 21565854 DOI: 10.1530/Joe-10-0418 |
0.807 |
|
| 2011 |
Erdos B, Kirichenko N, Whidden M, Basgut B, Woods M, Cudykier I, Tawil R, Scarpace PJ, Tumer N. Effect of age on high-fat diet-induced hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 301: H164-72. PMID 21551274 DOI: 10.1152/Ajpheart.01289.2010 |
0.542 |
|
| 2011 |
Shapiro A, Tümer N, Gao Y, Cheng KY, Scarpace PJ. Prevention and reversal of diet-induced leptin resistance with a sugar-free diet despite high fat content. The British Journal of Nutrition. 106: 390-7. PMID 21418711 DOI: 10.1017/S000711451100033X |
0.464 |
|
| 2011 |
Zhang Y, Rodrigues E, Li G, Gao Y, King M, Carter CS, Tumer N, Cheng KY, Scarpace PJ. Simultaneous POMC gene transfer to hypothalamus and brainstem increases physical activity, lipolysis and reduces adult-onset obesity. The European Journal of Neuroscience. 33: 1541-50. PMID 21366729 DOI: 10.1111/J.1460-9568.2011.07633.X |
0.549 |
|
| 2011 |
Matheny M, Shapiro A, Tümer N, Scarpace PJ. Region-specific diet-induced and leptin-induced cellular leptin resistance includes the ventral tegmental area in rats. Neuropharmacology. 60: 480-7. PMID 21059361 DOI: 10.1016/J.Neuropharm.2010.11.002 |
0.479 |
|
| 2011 |
Shapiro A, Cheng KY, Gao Y, Seo DO, Anton S, Carter CS, Zhang Y, Tumer N, Scarpace PJ. The act of voluntary wheel running reverses dietary hyperphagia and increases leptin signaling in ventral tegmental area of aged obese rats. Gerontology. 57: 335-42. PMID 20881371 DOI: 10.1159/000321343 |
0.569 |
|
| 2010 |
Zhang Y, Rodrigues E, Gao YX, King M, Cheng KY, Erdös B, Tümer N, Carter C, Scarpace PJ. Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity Neuroscience. 169: 1662-1671. PMID 20538045 DOI: 10.1016/J.Neuroscience.2010.06.001 |
0.561 |
|
| 2010 |
Scarpace PJ, Matheny M, Zhang Y. Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area Physiology and Behavior. 100: 173-179. PMID 20193697 DOI: 10.1016/J.Physbeh.2010.02.017 |
0.496 |
|
| 2010 |
Zhang Y, Collazo R, Gao Y, Li G, Scarpace PJ. Intermittent MTII application evokes repeated anorexia and robust fat and weight loss. Peptides. 31: 639-43. PMID 20034526 DOI: 10.1016/J.Peptides.2009.12.019 |
0.506 |
|
| 2009 |
Matheny M, Zhang Y, Shapiro A, Tümer N, Scarpace PJ. Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1254-61. PMID 19726711 DOI: 10.1152/Ajpregu.90449.2008 |
0.558 |
|
| 2009 |
Erdos B, Broxson CS, Cudykier I, Basgut B, Whidden M, Landa T, Scarpace PJ, Tümer N. Effect of high-fat diet feeding on hypothalamic redox signaling and central blood pressure regulation. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 32: 983-8. PMID 19713964 DOI: 10.1038/Hr.2009.129 |
0.504 |
|
| 2009 |
Judge MK, Zhang Y, Scarpace PJ. Responses to the cannabinoid receptor-1 antagonist, AM251, are more robust with age and with high-fat feeding. The Journal of Endocrinology. 203: 281-90. PMID 19679649 DOI: 10.1677/Joe-09-0210 |
0.827 |
|
| 2009 |
Zhang J, Scarpace PJ. The soluble leptin receptor neutralizes leptin-mediated STAT3 signalling and anorexic responses in vivo. British Journal of Pharmacology. 158: 475-82. PMID 19422379 DOI: 10.1111/J.1476-5381.2009.00246.X |
0.765 |
|
| 2009 |
Manfredsson FP, Tumer N, Erdos B, Landa T, Broxson CS, Sullivan LF, Rising AC, Foust KD, Zhang Y, Muzyczka N, Gorbatyuk OS, Scarpace PJ, Mandel RJ. Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 980-91. PMID 19277011 DOI: 10.1038/Mt.2009.45 |
0.496 |
|
| 2009 |
Scarpace PJ, Zhang Y. Leptin resistance: a prediposing factor for diet-induced obesity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R493-500. PMID 19091915 DOI: 10.1152/Ajpregu.90669.2008 |
0.484 |
|
| 2008 |
Shapiro A, Mu W, Roncal C, Cheng KY, Johnson RJ, Scarpace PJ. Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1370-5. PMID 18703413 DOI: 10.1152/Ajpregu.00195.2008 |
0.576 |
|
| 2008 |
Judge MK, Zhang J, Tümer N, Carter C, Daniels MJ, Scarpace PJ. Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 295: R773-R780. PMID 18596107 DOI: 10.1152/Ajpregu.00727.2007 |
0.785 |
|
| 2008 |
Shapiro A, Matheny M, Zhang Y, Tümer N, Cheng KY, Rogrigues E, Zolotukhin S, Scarpace PJ. Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats. Diabetes. 57: 614-22. PMID 18086903 DOI: 10.2337/Db07-0863 |
0.562 |
|
| 2007 |
Tümer N, Erdös B, Matheny M, Cudykier I, Scarpace PJ. Leptin antagonist reverses hypertension caused by leptin overexpression, but fails to normalize obesity-related hypertension. Journal of Hypertension. 25: 2471-8. PMID 17984669 DOI: 10.1097/Hjh.0B013E3282E9A9Fd |
0.446 |
|
| 2007 |
Erdös B, Broxson CS, Landa T, Scarpace PJ, Leeuwenburgh C, Zhang Y, Tümer N. Effects of life-long caloric restriction and voluntary exercise on age-related changes in levels of catecholamine biosynthetic enzymes and angiotensin II receptors in the rat adrenal medulla and hypothalamus. Experimental Gerontology. 42: 745-52. PMID 17540525 DOI: 10.1016/J.Exger.2007.04.007 |
0.406 |
|
| 2007 |
Li G, Zhang Y, Cheng KY, Scarpace PJ. Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central melanocortin responsiveness Diabetologia. 50: 1490-1499. PMID 17505816 DOI: 10.1007/S00125-007-0685-1 |
0.623 |
|
| 2007 |
Scarpace PJ, Zhang Y. Elevated leptin: consequence or cause of obesity? Frontiers in Bioscience : a Journal and Virtual Library. 12: 3531-44. PMID 17485319 DOI: 10.2741/2332 |
0.49 |
|
| 2007 |
Li G, Zhang Y, Rodrigues E, Zheng D, Matheny M, Cheng KY, Scarpace PJ. Melanocortin activation of nucleus of the solitary tract avoids anorectic tachyphylaxis and induces prolonged weight loss. American Journal of Physiology. Endocrinology and Metabolism. 293: E252-8. PMID 17389713 DOI: 10.1152/Ajpendo.00451.2006 |
0.541 |
|
| 2007 |
Scarpace PJ, Matheny M, Zhang Y, Cheng KY, Tümer N. Leptin antagonist reveals an uncoupling between leptin receptor signal transducer and activator of transcription 3 signaling and metabolic responses with central leptin resistance. The Journal of Pharmacology and Experimental Therapeutics. 320: 706-12. PMID 17082312 DOI: 10.1124/Jpet.106.112813 |
0.534 |
|
| 2007 |
Zhang J, Matheny MK, Tümer N, Mitchell MK, Scarpace PJ. Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R868-74. PMID 17023670 DOI: 10.1152/Ajpregu.00213.2006 |
0.816 |
|
| 2006 |
Zhang Y, Scarpace PJ. The role of leptin in leptin resistance and obesity. Physiology & Behavior. 88: 249-56. PMID 16782141 DOI: 10.1016/J.Physbeh.2006.05.038 |
0.441 |
|
| 2006 |
Zhang Y, Scarpace PJ. Circumventing central leptin resistance: lessons from central leptin and POMC gene delivery. Peptides. 27: 350-64. PMID 16274846 DOI: 10.1016/J.Peptides.2005.01.024 |
0.503 |
|
| 2006 |
Wilsey J, Matheny MK, Scarpace PJ. Oral vanadium enhances the catabolic effects of central leptin in young adult rats. Endocrinology. 147: 493-501. PMID 16195403 DOI: 10.1210/En.2004-1358 |
0.764 |
|
| 2006 |
Tümer N, Scarpace PJ, Dogan MD, Broxson CS, Matheny M, Yurek DM, Peden CS, Burger C, Muzyczka N, Mandel RJ. Hypothalamic rAAV-mediated GDNF gene delivery ameliorates age-related obesity. Neurobiology of Aging. 27: 459-70. PMID 15964099 DOI: 10.1016/J.Neurobiolaging.2005.03.018 |
0.557 |
|
| 2006 |
Aslanidi G, Philipsberg G, Kroutov V, Lamb K, Kohlbrenner E, Campbell-Thompson M, Walter G, Scarpace PJ, Zolotukhin S. 406. rAAV-Mediated Expression of Wnt10b cDNA Prevents the Development of Obesity in DIO Rats Molecular Therapy. 13: S156. DOI: 10.1016/J.Ymthe.2006.08.469 |
0.381 |
|
| 2005 |
Li G, Zhang Y, Wilsey JT, Scarpace PJ. Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats. Diabetologia. 48: 2376-85. PMID 16205885 DOI: 10.1007/S00125-005-1943-8 |
0.782 |
|
| 2005 |
Scarpace PJ, Matheny M, Tümer N, Cheng KY, Zhang Y. Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats Diabetologia. 48: 1075-1083. PMID 15864530 DOI: 10.1007/S00125-005-1763-X |
0.571 |
|
| 2004 |
Zhang Y, Matheny M, Tümer N, Scarpace PJ. Aged-obese rats exhibit robust responses to a melanocortin agonist and antagonist despite leptin resistance. Neurobiology of Aging. 25: 1349-60. PMID 15465633 DOI: 10.1016/J.Neurobiolaging.2004.02.012 |
0.543 |
|
| 2004 |
Li G, Zhang Y, Wilsey JT, Scarpace PJ. Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression. The Journal of Endocrinology. 182: 123-32. PMID 15225137 DOI: 10.1677/Joe.0.1820123 |
0.8 |
|
| 2004 |
Wilsey J, Scarpace PJ. Caloric restriction reverses the deficits in leptin receptor protein and leptin signaling capacity associated with diet-induced obesity: Role of leptin in the regulation of hypothalamic long-form leptin receptor expression Journal of Endocrinology. 181: 297-306. PMID 15128278 DOI: 10.1677/Joe.0.1810297 |
0.537 |
|
| 2004 |
Prima V, Tennant M, Gorbatyuk OS, Muzyczka N, Scarpace PJ, Zolotukhin S. Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: microarray deoxyribonucleic acid-chip analysis of gene expression. Endocrinology. 145: 2035-45. PMID 14715713 DOI: 10.1210/En.2003-1376 |
0.5 |
|
| 2003 |
Shklyaev S, Aslanidi G, Tennant M, Prima V, Kohlbrenner E, Kroutov V, Campbell-Thompson M, Crawford J, Shek EW, Scarpace PJ, Zolotukhin S. Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats. Proceedings of the National Academy of Sciences of the United States of America. 100: 14217-22. PMID 14617771 DOI: 10.1073/Pnas.2333912100 |
0.487 |
|
| 2003 |
Wilsey J, Zolotukhin S, Prima V, Scarpace PJ. Central leptin gene therapy fails to overcome leptin resistance associated with diet-induced obesity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R1011-20. PMID 14557234 DOI: 10.1152/Ajpregu.00193.2003 |
0.812 |
|
| 2003 |
Li G, Mobbs CV, Scarpace PJ. Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats. Diabetes. 52: 1951-7. PMID 12882910 DOI: 10.2337/Diabetes.52.8.1951 |
0.567 |
|
| 2003 |
Scarpace PJ, Matheny M, Zolotukhin S, Tümer N, Zhang Y. Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II. Neuropharmacology. 45: 211-9. PMID 12842127 DOI: 10.1016/S0028-3908(03)00158-8 |
0.537 |
|
| 2003 |
Kim YW, Scarpace PJ. Repeated fasting/refeeding elevates plasma leptin without increasing fat mass in rats. Physiology & Behavior. 78: 459-64. PMID 12676282 DOI: 10.1016/S0031-9384(03)00016-7 |
0.56 |
|
| 2002 |
Li G, Klein RL, Matheny M, King MA, Meyer EM, Scarpace PJ. Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in rats. Neuroscience. 115: 879-89. PMID 12435426 DOI: 10.1016/S0306-4522(02)00447-5 |
0.409 |
|
| 2002 |
Wilsey J, Zolotukhin S, Prima V, Shek EW, Matheny MK, Scarpace PJ. Hypothalmic delivery of doxycycline-inducible leptin gene allows for reversible transgene expression and physiological responses Gene Therapy. 9: 1492-1499. PMID 12407421 DOI: 10.1038/Sj.Gt.3301835 |
0.792 |
|
| 2002 |
Zhang Y, Matheny M, Zolotukhin S, Tumer N, Scarpace PJ. Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting. Biochimica Et Biophysica Acta. 1584: 115-22. PMID 12385894 DOI: 10.1016/S1388-1981(02)00298-6 |
0.439 |
|
| 2002 |
Zhang Y, Wilsey JT, Frase CD, Matheny MM, Bender BS, Zolotukhin S, Scarpace PJ. Peripheral but not central leptin prevents the immunosuppression associated with hypoleptinemia in rats. The Journal of Endocrinology. 174: 455-61. PMID 12208666 DOI: 10.1677/Joe.0.1740455 |
0.797 |
|
| 2002 |
Scarpace PJ, Matheny M, Zhang Y, Shek EW, Prima V, Zolotukhin S, Tümer N. Leptin-induced leptin resistance reveals separate roles for the anorexic and thermogenic responses in weight maintenance. Endocrinology. 143: 3026-35. PMID 12130569 DOI: 10.1210/Endo.143.8.8966 |
0.514 |
|
| 2002 |
Scarpace PJ, Matheny M, Zhang Y, Tümer N, Frase CD, Shek EW, Hong B, Prima V, Zolotukhin S. Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats Neuropharmacology. 42: 548-561. PMID 11955525 DOI: 10.1016/S0028-3908(02)00003-5 |
0.606 |
|
| 2002 |
Borst SE, Snellen HG, Ross H, Scarpace PJ, Kim YW. Metformin restores responses to insulin but not to growth hormone in Sprague-Dawley rats. Biochemical and Biophysical Research Communications. 291: 722-6. PMID 11855850 DOI: 10.1006/Bbrc.2002.6498 |
0.438 |
|
| 2001 |
Scarpace PJ, Tümer N. Peripheral and hypothalamic leptin resistance with age-related obesity Physiology and Behavior. 74: 721-727. PMID 11790435 DOI: 10.1016/S0031-9384(01)00616-3 |
0.569 |
|
| 2001 |
Scarpace PJ, Matheny M, Tümer N. Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats Neuroscience. 104: 1111-1117. PMID 11457594 DOI: 10.1016/S0306-4522(01)00142-7 |
0.573 |
|
| 2001 |
Dhillon H, Kalra SP, Prima V, Zolotukhin S, Scarpace PJ, Moldawer LL, Muzyczka N, Kalra PS. Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study. Regulatory Peptides. 99: 69-77. PMID 11384767 DOI: 10.1016/S0167-0115(01)00237-3 |
0.521 |
|
| 2001 |
Koller MM, Cowman RA, Humphreys-Beher MG, Scarpace PJ. An analysis of parotid salivary gland function with desipramine and age in female NIA Fischer 344 rats Experimental Gerontology. 36: 141-157. PMID 11162918 DOI: 10.1016/S0531-5565(00)00188-1 |
0.394 |
|
| 2000 |
Koller MM, Purushotham KR, Maeda N, Scarpace PJ, Humphreys-Beher MG. Desipramine induced changes in salivary proteins, cultivable oral microbiota and gingival health in aging female NIA Fischer 344 rats Life Sciences. 68: 445-455. PMID 11205893 DOI: 10.1016/S0024-3205(00)00951-6 |
0.388 |
|
| 2000 |
Scarpace PJ, Kumar MV, Li H, Tümer N. Uncoupling proteins 2 and 3 with age: Regulation by fasting and β3-adrenergic agonist treatment Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 55. PMID 11129388 DOI: 10.1093/Gerona/55.12.B588 |
0.444 |
|
| 2000 |
Koller MM, Cowman RA, Humphreys-Beher MG, Scarpace PJ. An analysis of submandibular salivary gland function with desipramine and age in female NIA Fischer 344 rats Mechanisms of Ageing and Development. 119: 131-147. PMID 11080533 DOI: 10.1016/S0047-6374(00)00176-7 |
0.408 |
|
| 2000 |
Koller MM, Maeda N, Scarpace PJ, Humphreys-Beher MG. Desipramine changes salivary gland function, oral microbiota, and oral health in rats European Journal of Pharmacology. 408: 91-98. PMID 11070187 DOI: 10.1016/S0014-2999(00)00770-6 |
0.311 |
|
| 2000 |
Shek EW, Scarpace PJ. Resistance to the anorexic and thermogenic effects of centrally administrated leptin in obese aged rats Regulatory Peptides. 92: 65-71. PMID 11024567 DOI: 10.1016/S0167-0115(00)00151-8 |
0.467 |
|
| 2000 |
Scarpace PJ, Matheny M, Shek EW. Impaired leptin signal transduction with age-related obesity Neuropharmacology. 39: 1872-1879. PMID 10884568 DOI: 10.1016/S0028-3908(00)00014-9 |
0.524 |
|
| 2000 |
Scarpace PJ, Matheny M, Moore RL, Tümer N. Impaired leptin responsiveness in aged rats. Diabetes. 49: 431-5. PMID 10868965 DOI: 10.2337/Diabetes.49.3.431 |
0.562 |
|
| 2000 |
Scarpace PJ, Matheny M, Moore RL, Kumar MV. Modulation of uncoupling protein 2 and uncoupling protein 3: regulation by denervation, leptin and retinoic acid treatment. The Journal of Endocrinology. 164: 331-7. PMID 10694373 DOI: 10.1677/Joe.0.1640331 |
0.314 |
|
| 2000 |
Scarpace PJ, Tümer N. Leptin resistance with age-related obesity Rejuvenation Research. 3: 183-189. DOI: 10.1089/Rej.1.2000.3.183 |
0.59 |
|
| 1999 |
Tümer N, Broxson CS, LaRochelle JS, Scarpace PJ. Induction of tyrosine hydroxylase and neuropeptide Y by carbachol: Modulation with age Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 54. PMID 10568524 DOI: 10.1093/Gerona/54.10.B418 |
0.4 |
|
| 1999 |
Kumar MV, Moore RL, Scarpace PJ. Beta3-adrenergic regulation of leptin, food intake, and adiposity is impaired with age. PflüGers Archiv : European Journal of Physiology. 438: 681-8. PMID 10555566 DOI: 10.1007/s004240051093 |
0.498 |
|
| 1999 |
Kumar MV, Sunvold GD, Scarpace PJ. Dietary vitamin A supplementation in rats: Suppression of leptin and induction of UCP1 mRNA Journal of Lipid Research. 40: 824-829. PMID 10224151 |
0.334 |
|
| 1999 |
Scarpace PJ, Matheny M, Tümer N. Differential down-regulation of β3-adrenergic receptor mRNA and signal transduction by cold exposure in brown adipose tissue of young and senescent rats Pflugers Archiv European Journal of Physiology. 437: 479-483. PMID 9914406 DOI: 10.1007/S004240050804 |
0.426 |
|
| 1998 |
Li H, Matheny M, Tümer N, Scarpace PJ. Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression. American Journal of Physiology. Endocrinology and Metabolism. 275: E405-E411. PMID 29585554 DOI: 10.1152/ajpendo.1998.275.3.E405 |
0.382 |
|
| 1998 |
Scarpace PJ, Matheny M. Leptin induction of UCP1 gene expression is dependent on sympathetic innervation. American Journal of Physiology. Endocrinology and Metabolism. 275: E259-E264. PMID 29585186 DOI: 10.1152/ajpendo.1998.275.2.E259 |
0.364 |
|
| 1998 |
Scarpace PJ, Nicolson M, Matheny M. UCP2, UCP3 and leptin gene expression: Modulation by food restriction and leptin Journal of Endocrinology. 159: 349-357. PMID 9795377 DOI: 10.1677/Joe.0.1590349 |
0.434 |
|
| 1998 |
Li H, Matheny M, Tümer N, Scarpace PJ. Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression American Journal of Physiology - Endocrinology and Metabolism. 275. PMID 9725806 DOI: 10.1152/Ajpendo.1998.275.3.E405 |
0.482 |
|
| 1998 |
Scarpace PJ, Matheny M. Leptin induction of UCP1 gene expression is dependent on sympathetic innervation American Journal of Physiology - Endocrinology and Metabolism. 275. PMID 9688627 DOI: 10.1152/Ajpendo.1998.275.2.E259 |
0.466 |
|
| 1997 |
Li H, Matheny M, Nicolson M, Tümer N, Scarpace PJ. Leptin gene expression increases with age independent of increasing adiposity in rats Diabetes. 46: 2035-2039. PMID 9392492 |
0.37 |
|
| 1997 |
Tümer N, Scarpace PJ, Baker HV, Larochelle JS. AP-1 transcription factor binding activity in rat adrenal medulla and hypothalamus with age and cold exposure Neuropharmacology. 36: 1065-1069. PMID 9294971 DOI: 10.1016/S0028-3908(97)00093-2 |
0.394 |
|
| 1997 |
Scarpace PJ, Matheny M, Pollock BH, Tümer N. Leptin increases uncoupling protein expression and energy expenditure American Journal of Physiology - Endocrinology and Metabolism. 273. PMID 9252501 DOI: 10.1152/Ajpendo.1997.273.1.E226 |
0.495 |
|
| 1997 |
Li H, Matheny M, Scarpace PJ. β3-Adrenergic-mediated suppression of leptin gene expression in rats American Journal of Physiology - Endocrinology and Metabolism. 272. PMID 9227448 DOI: 10.1152/Ajpendo.1997.272.6.E1031 |
0.441 |
|
| 1997 |
Tümer N, Bowman CJ, LaRochelle JS, Kelley A, Scarpace PJ. Induction of tyrosine hydroxylase by forskolin: Modulation with age European Journal of Pharmacology. 324: 57-62. PMID 9137913 DOI: 10.1016/S0014-2999(97)00055-1 |
0.421 |
|
| 1997 |
Scarpace PJ. Thermoregulation with age: Role of beta-adrenergic signal transduction Annals of the New York Academy of Sciences. 813: 111-116. PMID 9100870 DOI: 10.1111/J.1749-6632.1997.Tb51680.X |
0.417 |
|
| 1997 |
Scarpace PJ, Matheny M. Leptin increases uncoupling protein expression in brown adiplse tissue along with energy expenditure Faseb Journal. 11. |
0.347 |
|
| 1996 |
Tümer N, Sego RL, Scarpace PJ. Atypical pattern of adenylyl cyclase activity in the adrenal medulla with age Experimental Gerontology. 31: 571-576. PMID 9415112 DOI: 10.1016/0531-5565(96)00053-8 |
0.399 |
|
| 1996 |
Scarpace PJ, Dove J, Matheny M. Effects of age on β adrenergic subtype activation of adenylyl cyclase in brown adipose tissue Proceedings of the Society For Experimental Biology and Medicine. 213: 262-267. PMID 8985310 DOI: 10.3181/00379727-213-44058 |
0.328 |
|
| 1996 |
Scarpace PJ, Matheny M, Tümer N. Myocardial adenylyl cyclase type V and VI mRNA: Differential regulation with age Journal of Cardiovascular Pharmacology. 27: 86-90. PMID 8656664 DOI: 10.1097/00005344-199601000-00014 |
0.337 |
|
| 1996 |
Scarpace PJ, Tse C, Matheny M. Thermoregulation with age: Restoration of β3-adrenergic responsiveness in brown adipose tissue by cold exposure Proceedings of the Society For Experimental Biology and Medicine. 211: 374-380. PMID 8618944 DOI: 10.3181/00379727-211-43983 |
0.425 |
|
| 1996 |
Scarpace PJ, Matheny M. Thermogenesis in brown adipose tissue with age: Post-receptor activation by forskolin PflüGers Archiv European Journal of Physiology. 431: 388-394. PMID 8584432 DOI: 10.1007/Bf02207276 |
0.477 |
|
| 1994 |
Borst SE, Oliver RJ, Scarpace PJ. Alpha1-adrenergic and arginine vasopressin stimulation of inositide hydrolysis in rat hepatocytes is unaltered in senescence Journals of Gerontology. 49. PMID 8282972 DOI: 10.1093/Geronj/49.1.B18 |
0.343 |
|
| 1994 |
Scarpace PJ, Matheny M, Borst S, Tümer N. Thermoregulation with Age: Role of Thermogenesis and Uncoupling Protein Expression in Brown Adipose Tissue Proceedings of the Society For Experimental Biology and Medicine. 205: 154-161. PMID 8108465 DOI: 10.3181/00379727-205-43691 |
0.44 |
|
| 1994 |
Rajakumar G, Scarpace PJ. Relationship between cAMP production and protein secretion in rat submandibular acini: Evidence for loss of reserve capacity with age Life Sciences. 55: 761-766. PMID 8072373 DOI: 10.1016/0024-3205(94)00559-1 |
0.385 |
|
| 1994 |
Sanghani MP, Scarpace PJ. Atypical β-adrenergic receptors in rat liver: Evidence for transient expression during aging Journals of Gerontology. 49. PMID 7907351 DOI: 10.1093/Geronj/49.2.B60 |
0.336 |
|
| 1994 |
Scarpace PJ, Yenice S, Tümer N. Influence of exercise training and age on uncoupling protein mRNA expression in brown adipose tissue Pharmacology, Biochemistry and Behavior. 49: 1057-1059. PMID 7886075 DOI: 10.1016/0091-3057(94)90264-X |
0.354 |
|
| 1994 |
Borst SE, Oliver RJ, Sego RL, Scarpace PJ. α-Adrenergic receptor-mediated thermogenesis in brown adipose tissue of rat General Pharmacology. 25: 1703-1710. PMID 7721049 DOI: 10.1016/0306-3623(94)90375-1 |
0.333 |
|
| 1994 |
Shu Y, Scarpace PJ. Forskolin binding sites and G-protein immunoreactivity in rat hearts during aging Journal of Cardiovascular Pharmacology. 2: 188-193. PMID 7511746 DOI: 10.1097/00005344-199402000-00003 |
0.403 |
|
| 1993 |
Crass MF, Scarpace PJ. Vasoactive properties of a parathyroid hormone-related protein in the rat aorta Peptides. 14: 179-183. PMID 8387185 DOI: 10.1016/0196-9781(93)90027-E |
0.352 |
|
| 1993 |
Scarpace PJ, Koller MM, Rajakumar G. Desipramine desensitizes β-adrenergic signal transduction in salivary glands: differential regulation with age European Journal of Pharmacology: Molecular Pharmacology. 247: 65-72. PMID 8258362 DOI: 10.1016/0922-4106(93)90138-Y |
0.433 |
|
| 1993 |
Mooradian AD, Scarpace PJ. 3,5,3′-l-Triiodothyronine regulation of β-adrenergic receptor density and adenylyl cyclase activity in synaptosomal membranes of aged rats Neuroscience Letters. 161: 101-104. PMID 8255534 DOI: 10.1016/0304-3940(93)90150-J |
0.435 |
|
| 1992 |
Scarpace PJ, Borst SE, Bender BS. The association of E. coli peritonitis with an impaired and delayed fever response in senescent rats Journals of Gerontology. 47. PMID 1624691 DOI: 10.1093/Geronj/47.4.B142 |
0.408 |
|
| 1992 |
Scarpace PJ, Matheny M, Bender BS, Borst SE. Impaired Febrile Response with Age: Role of Thermogenesis in Brown Adipose Tissue (43442) Proceedings of the Society For Experimental Biology and Medicine. 200: 353-358. PMID 1615011 DOI: 10.3181/00379727-200-43442 |
0.42 |
|
| 1992 |
Scarpace PJ, Matheny M, Borst SE. Thermogenesis and mitochondrial GDP binding with age in response to the novel agonist CGP-12177A American Journal of Physiology - Endocrinology and Metabolism. 262. PMID 1539643 DOI: 10.1152/Ajpendo.1992.262.2.E185 |
0.395 |
|
| 1992 |
Koller MM, Maeda N, Purushotham KR, Scarpace PJ, Humphreys-Beher MG. A biochemical analysis of parotid and submandibular salivary gland function with age after simultaneous stimulation with pilocarpine and isoproterenol in female NIA Fischer 344 rats Archives of Oral Biology. 37: 219-230. PMID 1375022 DOI: 10.1016/0003-9969(92)90092-M |
0.303 |
|
| 1992 |
Scarpace PJ, Koller MM, Rajakumar G. Desipramine desensitizes β-adrenergic signal transduction in rat salivary glands Neuropharmacology. 31: 1305-1309. PMID 1335132 DOI: 10.1016/0028-3908(92)90060-3 |
0.389 |
|
| 1992 |
Scarpace PJ, Lowenthal DT, Tümer N. Influence of exercise and age on myocardial β-adrenergic receptor properties Experimental Gerontology. 27: 169-177. PMID 1325922 DOI: 10.1016/0531-5565(92)90041-W |
0.348 |
|
| 1992 |
Mooradian AD, Scarpace PJ. β-Adrenergic receptor activity of cerebral microvessels in experimental diabetes mellitus Brain Research. 583: 155-160. PMID 1324092 DOI: 10.1016/S0006-8993(10)80019-8 |
0.343 |
|
| 1992 |
Crass MF, Borst SE, Scarpace PJ. β-adrenergic responsiveness in cultured aorta smooth muscle cells Effects of subculture and aging Biochemical Pharmacology. 43: 1811-1815. PMID 1315546 DOI: 10.1016/0006-2952(92)90714-T |
0.368 |
|
| 1991 |
Mooradian AD, Scarpace PJ. β-Adrenergic receptor activity of cerebral microvessels is reduced in aged rats Neurochemical Research. 16: 447-451. PMID 1681437 DOI: 10.1007/Bf00965565 |
0.395 |
|
| 1991 |
Scarpace PJ, Turner N, Mader SL. β-Adrenergic Function in Aging: Basic Mechanisms and Clinical Implications Drugs &Amp; Aging. 1: 116-129. PMID 1665371 DOI: 10.2165/00002512-199101020-00004 |
0.396 |
|
| 1991 |
Rajakumar G, Scarpace PJ. β-Adrenergic signal transduction in aging parotid and submandibular salivary glands Journals of Gerontology. 46. PMID 1658113 DOI: 10.1093/Geronj/46.6.B249 |
0.356 |
|
| 1991 |
Scarpace PJ, Bender BS, Borst SE. Escherichia coli peritonitis activates thermogenesis in brown adipose tissue: Relationship to fever Canadian Journal of Physiology and Pharmacology. 69: 761-766. PMID 1655179 DOI: 10.1139/Y91-113 |
0.349 |
|
| 1990 |
Borst SE, Scarpace PJ. Alpha1-adrenergic stimulation of inositide hydrolysis in liver of senescent rats Mechanisms of Ageing and Development. 56: 275-280. PMID 1965214 DOI: 10.1016/0047-6374(90)90088-W |
0.381 |
|
| 1990 |
Borst SE, Scarpace PJ. Reduced high-affinity α1-adrenoceptors in liver of senescent rats: Implications of assessment at various temperatures British Journal of Pharmacology. 101: 650-654. PMID 1963803 DOI: 10.1111/J.1476-5381.1990.Tb14135.X |
0.347 |
|
| 1990 |
Borst SE, Narang N, Crews FT, Scarpace PJ. Reduced alpha 1-adrenergic receptor-mediated inositide hydrolysis in cardiac atria of senescent rats. Journal of Cardiovascular Pharmacology. 16: 444-8. PMID 1700216 DOI: 10.1097/00005344-199009000-00014 |
0.4 |
|
| 1988 |
Mooradian AD, Morley JE, Scarpace PJ. The role of zinc status in altered cardiac adenylate cyclase activity in diabetic rats Acta Endocrinologica. 119: 174-180. PMID 2845690 DOI: 10.1530/Acta.0.1190174 |
0.373 |
|
| 1988 |
Scarpace PJ, Mooradian AD, Morley JE. Age-associated decrease in beta-adrenergic receptors and adenylate cyclase activity in rat brown adipose tissue Journals of Gerontology. 43. PMID 2834431 |
0.341 |
|
| 1981 |
Scarpace PJ, Abrass IB. Thyroid hormone regulation of β-adrenergic receptor number in aging rats Endocrinology. 108: 1276-1278. PMID 6258903 DOI: 10.1210/Endo-108-4-1276 |
0.43 |
|
| 1981 |
Abrass IB, Scarpace PJ. Glucocorticoid regulation of myocardial β-adrenergic receptors Endocrinology. 108: 977-980. PMID 6257502 DOI: 10.1210/Endo-108-3-977 |
0.336 |
|
| 1981 |
Scarpace PJ, Abrass IB. Thyroid hormone regulation of rat heart, lymphocyte, and lung β-adrenergic receptors Endocrinology. 108: 1007-1011. PMID 6257494 DOI: 10.1210/Endo-108-3-1007 |
0.337 |
|
| Show low-probability matches. |