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Joseph N. Contessa, Ph.D. - Publications

Affiliations: 
2002 Virginia Commonwealth University, Richmond, VA, United States 
Area:
Molecular Biology, Cell Biology, Medical Biophysics, Oncology
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wong SJ, Torres-Saavedra PA, Saba NF, Shenouda G, Bumpous JM, Wallace RE, Chung CH, El-Naggar AK, Gwede CK, Burtness B, Tennant PA, Dunlap NE, Redman R, Stokes WA, Rudra S, ... ... Contessa JN, et al. Radiotherapy Plus Cisplatin With or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial. Jama Oncology. PMID 37768670 DOI: 10.1001/jamaoncol.2023.3809  0.35
2021 Petrulli JR, Zheng M, Huang Y, Nabulsi NB, Goldberg SB, Contessa JN, Morris ED. Evaluation of quantitative modeling methods in whole-body, dynamic [C]-erlotinib PET. American Journal of Nuclear Medicine and Molecular Imaging. 11: 143-153. PMID 34079641  0.318
2019 Baro M, Lopez Sambrooks C, Burtness BA, Lemmon MA, Contessa JN. Neuregulin Signaling is a Mechanism of Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma. Molecular Cancer Therapeutics. PMID 31387891 DOI: 10.1158/1535-7163.Mct-19-0163  0.374
2019 Klaver E, Zhao P, May M, Flanagan-Steet H, Freeze HH, Gilmore R, Wells L, Contessa J, Steet R. Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing. Disease Models & Mechanisms. PMID 31101650 DOI: 10.1242/Dmm.039602  0.37
2018 Lopez Sambrooks C, Baro M, Quijano A, Narayan A, Wei C, Greninger P, Egan RK, Patel AA, Benes CH, Saltzman WM, Contessa JN. Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors. Cancer Research. PMID 30026325 DOI: 10.1158/0008-5472.Can-18-0505  0.453
2018 Baro M, Lopez Sambrooks C, Quijano A, Saltzman WM, Contessa JN. Oligosaccharyltransferase inhibition Reduces Receptor Tyrosine Kinase Activation and Enhances Glioma Radiosensitivity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29967251 DOI: 10.1158/1078-0432.Ccr-18-0792  0.411
2017 Petrulli JR, Hansen SB, Abourbeh G, Yaqub M, Bahce I, Holden D, Huang Y, Nabulsi NB, Contessa JN, Mishani E, Lammertsma AA, Morris ED. A multi species evaluation of the radiation dosimetry of [(11)C]erlotinib, the radiolabeled analog of a clinically utilized tyrosine kinase inhibitor. Nuclear Medicine and Biology. 47: 56-61. PMID 28126682 DOI: 10.1016/J.Nucmedbio.2016.12.009  0.424
2017 Magnuson WJ, Lester-Coll NH, Wu AJ, Yang TJ, Lockney NA, Gerber NK, Beal K, Amini A, Patil T, Kavanagh BD, Camidge DR, Braunstein SE, Boreta LC, Balasubramanian SK, Ahluwalia MS, ... ... Contessa JN, et al. Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naïve Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016697144. PMID 28113019 DOI: 10.1200/JCO.2016.69.7144  0.374
2016 Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nature Chemical Biology. PMID 27694802 DOI: 10.1038/Nchembio.2194  0.425
2016 Magnuson WJ, Amini A, Patil T, Kavanagh BD, Camidge DR, Braunstein SE, Boreta L, Attia A, Rana N, Contessa JN, Gettinger SN, Lester-Coll NH, Yu JB, Chiang VL. Deferring Radiation Therapy for Brain Metastases in Patients With EGFR-Mutant Non-Small Cell Lung Cancer: A Multi-Institutional Analysis. International Journal of Radiation Oncology, Biology, Physics. 96: S57-S58. PMID 27675963 DOI: 10.1016/j.ijrobp.2016.06.149  0.306
2014 Cazet A, Charest J, Bennett DC, Sambrooks CL, Contessa JN. Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity. Plos One. 9: e110345. PMID 25314669 DOI: 10.1371/journal.pone.0110345  0.438
2013 Petrulli JR, Sullivan JM, Zheng MQ, Bennett DC, Charest J, Huang Y, Morris ED, Contessa JN. Quantitative analysis of [11C]-erlotinib PET demonstrates specific binding for activating mutations of the EGFR kinase domain. Neoplasia (New York, N.Y.). 15: 1347-53. PMID 24403856 DOI: 10.1593/Neo.131666  0.395
2013 Bennett DC, Charest J, Sebolt K, Lehrman M, Rehemtulla A, Contessa JN. High-throughput screening identifies aclacinomycin as a radiosensitizer of EGFR-mutant non-small cell lung cancer. Translational Oncology. 6: 382-91. PMID 23730419 DOI: 10.1593/tlo.13232  0.359
2011 Khan AP, Contessa JN, Nyati MK, Ross BD, Rehemtulla A. Molecular imaging of epidermal growth factor receptor kinase activity. Analytical Biochemistry. 417: 57-64. PMID 21693098 DOI: 10.1016/j.ab.2011.05.040  0.524
2010 Contessa JN, Bhojani MS, Freeze HH, Ross BD, Rehemtulla A, Lawrence TS. Molecular imaging of N-linked glycosylation suggests glycan biosynthesis is a novel target for cancer therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3205-14. PMID 20413434 DOI: 10.1158/1078-0432.CCR-09-3331  0.413
2008 Contessa JN, Bhojani MS, Freeze HH, Rehemtulla A, Lawrence TS. Inhibition of N-linked glycosylation disrupts receptor tyrosine kinase signaling in tumor cells. Cancer Research. 68: 3803-9. PMID 18483264 DOI: 10.1158/0008-5472.CAN-07-6389  0.414
2008 Contessa JN, Hamstra DA. Revoking the privilege: targeting HER2 in the central nervous system. Molecular Pharmacology. 73: 271-3. PMID 17981994 DOI: 10.1124/mol.107.042986  0.341
2006 Contessa JN, Abell A, Valerie K, Lin PS, Schmidt-Ullrich RK. ErbB receptor tyrosine kinase network inhibition radiosensitizes carcinoma cells. International Journal of Radiation Oncology, Biology, Physics. 65: 851-8. PMID 16751066 DOI: 10.1016/J.Ijrobp.2006.02.025  0.713
2006 Contessa JN, Abell A, Mikkelsen RB, Valerie K, Schmidt-Ullrich RK. Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation. Breast Cancer Research and Treatment. 95: 17-27. PMID 16267617 DOI: 10.1007/S10549-005-9023-9  0.689
2003 Lammering G, Hewit TH, Valerie K, Lin PS, Contessa JN, Schmidt-Ullrich RK. Anti-erbB receptor strategy as a gene therapeutic intervention to improve radiotherapy in malignant human tumours. International Journal of Radiation Biology. 79: 561-8. PMID 14530165 DOI: 10.1080/0955300031000102632  0.606
2003 Schmidt-Ullrich RK, Contessa JN, Lammering G, Amorino G, Lin PS. ERBB receptor tyrosine kinases and cellular radiation responses. Oncogene. 22: 5855-65. PMID 12947392 DOI: 10.1038/Sj.Onc.1206698  0.717
2003 Lammering G, Hewit TH, Valerie K, Contessa JN, Amorino GP, Dent P, Schmidt-Ullrich RK. EGFRvIII-mediated radioresistance through a strong cytoprotective response. Oncogene. 22: 5545-53. PMID 12944901 DOI: 10.1038/Sj.Onc.1206788  0.733
2003 Dent P, Yacoub A, Contessa J, Caron R, Amorino G, Valerie K, Hagan MP, Grant S, Schmidt-Ullrich R. Stress and radiation-induced activation of multiple intracellular signaling pathways. Radiation Research. 159: 283-300. PMID 12600231 DOI: 10.1667/0033-7587(2003)159[0283:Sariao]2.0.Co;2  0.646
2002 Contessa JN, Hampton J, Lammering G, Mikkelsen RB, Dent P, Valerie K, Schmidt-Ullrich RK. Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells. Oncogene. 21: 4032-41. PMID 12037685 DOI: 10.1038/Sj.Onc.1205500  0.67
2002 Contessa J, Abell A, Lammering G, Hewit T, Valerie K, Schmidt-Ullrich R. EGRF-CD533 acts as a PAN-ERBB receptor tyrosine kinase inhibitor International Journal of Radiation Oncology*Biology*Physics. 54: 175-176. DOI: 10.1016/S0360-3016(02)03361-8  0.646
2001 Lammering G, Lin PS, Contessa JN, Hampton JL, Valerie K, Schmidt-Ullrich RK. Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells. International Journal of Radiation Oncology, Biology, Physics. 51: 775-84. PMID 11697324 DOI: 10.1016/S0360-3016(01)01714-X  0.723
2001 Lammering G, Hewit TH, Hawkins WT, Contessa JN, Reardon DB, Lin PS, Valerie K, Dent P, Mikkelsen RB, Schmidt-Ullrich RK. Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization. Journal of the National Cancer Institute. 93: 921-9. PMID 11416113 DOI: 10.1093/Jnci/93.12.921  0.718
2001 Lammering G, Valerie K, Lin PS, Mikkelsen RB, Contessa JN, Feden JP, Farnsworth J, Dent P, Schmidt-Ullrich RK. Radiosensitization of malignant glioma cells through overexpression of dominant-negative epidermal growth factor receptor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 682-90. PMID 11297265  0.717
2001 Lammering G, Hewit T, Contessa J, Hawkins W, Lin P, Valerie K, Mikkelsen R, Dent P, Schmidt-Ullrich R. EGFR and its mutant EGFRvIII as modulators of tumor cell radiosensitivity International Journal of Radiation Oncology*Biology*Physics. 51: 103. DOI: 10.1016/S0360-3016(01)02012-0  0.696
1999 Schmidt-Ullrich RK, Contessa JN, Dent P, Mikkelsen RB, Valerie K, Reardon DB, Bowers G, Lin PS. Molecular mechanisms of radiation-induced accelerated repopulation. Radiation Oncology Investigations. 7: 321-30. PMID 10644055 DOI: 10.1002/(Sici)1520-6823(1999)7:6<321::Aid-Roi2>3.0.Co;2-Q  0.519
1999 Reardon DB, Contessa JN, Mikkelsen RB, Valerie K, Amir C, Dent P, Schmidt-Ullrich RK. Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells. Oncogene. 18: 4756-66. PMID 10467423 DOI: 10.1038/Sj.Onc.1202849  0.74
1999 Contessa JN, Reardon DB, Todd D, Dent P, Mikkelsen RB, Valerie K, Bowers GD, Schmidt-Ullrich RK. The inducible expression of dominant-negative epidermal growth factor receptor-CD533 results in radiosensitization of human mammary carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 405-11. PMID 10037190  0.74
1999 Schmidt-ullrich R, Bowers G, Dent P, Reardon D, Contessa J, Valerie K. 29 ERBB receptor tyrosine kinases as determinants of cytoprotective and cytotoxic radiation responses of carcinoma cells International Journal of Radiation Oncology*Biology*Physics. 45: 161-162. DOI: 10.1016/S0360-3016(99)90047-0  0.696
1998 Auer KL, Contessa J, Brenz-Verca S, Pirola L, Rusconi S, Cooper G, Abo A, Wymann MP, Davis RJ, Birrer M, Dent P. The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes. Molecular Biology of the Cell. 9: 561-73. PMID 9487126 DOI: 10.1091/Mbc.9.3.561  0.355
1997 Schmidt-Ullrich RK, Mikkelsen RB, Dent P, Todd DG, Valerie K, Kavanagh BD, Contessa JN, Rorrer WK, Chen PB. Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene. 15: 1191-7. PMID 9294612 DOI: 10.1038/Sj.Onc.1201275  0.704
1996 Schmidt-Ullrich R, Mikkelsen R, Valerie K, Todd D, Kavanagh B, Contessa J, Rorrer K, Chen P. 134 Molecular mechanisms of radiation-induced cell proliferation in human carcinoma cells International Journal of Radiation Oncology*Biology*Physics. 36: 225. DOI: 10.1016/S0360-3016(97)85475-2  0.607
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