Roland Kanaar, PhD - Publications

Genetics and Cell Biology Erasmus Medical Center Rotterdam, Rotterdam, Netherlands 
DNA Repair

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Harnicek D, Kampmann E, Lauber K, Hennel R, Cardoso Martins AS, Guo Y, Belka C, Mörtl S, Gallmeier E, Kanaar R, Mansmann U, Hucl T, Lindner LH, Hiddemann W, Issels RD. Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair. International Journal of Cancer. PMID 26933761 DOI: 10.1002/ijc.30070  1
2016 Issels R, Kampmann E, Kanaar R, Lindner LH. Hallmarks of hyperthermia in driving the future of clinical hyperthermia as targeted therapy: translation into clinical application. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 1-7. PMID 26803991 DOI: 10.3109/02656736.2015.1119317  1
2015 Naipal KA, Verkaik NS, Sánchez H, van Deurzen CH, den Bakker MA, Hoeijmakers JH, Kanaar R, Vreeswijk MP, Jager A, van Gent DC. Tumor slice culture system to assess drug response of primary breast cancer. Bmc Cancer. 16: 78. PMID 26860465 DOI: 10.1186/s12885-016-2119-2  1
2015 Tham KC, Kanaar R, Lebbink JH. Mismatch repair and homeologous recombination. Dna Repair. PMID 26739221 DOI: 10.1016/j.dnarep.2015.11.010  1
2015 Ameziane N, May P, Haitjema A, van de Vrugt HJ, van Rossum-Fikkert SE, Ristic D, Williams GJ, Balk J, Rockx D, Li H, Rooimans MA, Oostra AB, Velleuer E, Dietrich R, Bleijerveld OB, ... ... Kanaar R, et al. A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51. Nature Communications. 6: 8829. PMID 26681308 DOI: 10.1038/Ncomms9829  1
2015 Ramnath NW, Hawinkels LJ, van Heijningen PM, Riet LT, Paauwe M, Vermeij M, Danser AH, Kanaar R, Ten Dijke P, Essers J. Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels. Scientific Reports. 5: 16872. PMID 26607280 DOI: 10.1038/srep16872  1
2015 Naipal KA, Raams A, Bruens ST, Brandsma I, Verkaik NS, Jaspers NG, Hoeijmakers JH, van Leenders GJ, Pothof J, Kanaar R, Boormans J, van Gent DC. Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer. Plos One. 10: e0126029. PMID 25927440 DOI: 10.1371/journal.pone.0126029  1
2015 Braks JA, Spiegelberg L, Koljenovic S, Ridwan Y, Keereweer S, Kanaar R, Wolvius EB, Essers J. Optical Imaging of Tumor Response to Hyperbaric Oxygen Treatment and Irradiation in an Orthotopic Mouse Model of Head and Neck Squamous Cell Carcinoma. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 25724406 DOI: 10.1007/s11307-015-0834-8  1
2015 Uringa EJ, Baldeyron C, Odijk H, Wassenaar E, van Cappellen WA, Maas A, Hoeijmakers JH, Baarends WM, Kanaar R, Essers J. A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity. Dna Repair. 25: 27-40. PMID 25463395 DOI: 10.1016/j.dnarep.2014.11.002  1
2015 Pont LM, Naipal K, Kloezeman JJ, Venkatesan S, van den Bent M, van Gent DC, Dirven CM, Kanaar R, Lamfers ML, Leenstra S. DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells. Cancer Letters. 356: 525-35. PMID 25305451 DOI: 10.1016/j.canlet.2014.09.049  1
2015 Reuter M, Zelensky A, Smal I, Meijering E, van Cappellen WA, Martijn de Gruiter H, van Belle GJ, van Royen ME, Houtsmuller AB, Essers J, Kanaar R, Wyman C. Correction to: "BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells" [J. Cell Biol. Vol. 207 No. 5, December 8, 2014. Pages 599-613] Journal of Cell Biology. 208: 857-857.  1
2014 Reuter M, Zelensky A, Smal I, Meijering E, van Cappellen WA, de Gruiter HM, van Belle GJ, van Royen ME, Houtsmuller AB, Essers J, Kanaar R, Wyman C. BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells. The Journal of Cell Biology. 207: 599-613. PMID 25488918 DOI: 10.1083/jcb.201405014  1
2014 Zelensky A, Kanaar R, Wyman C. Mediators of homologous DNA pairing. Cold Spring Harbor Perspectives in Biology. 6: a016451. PMID 25301930 DOI: 10.1101/Cshperspect.A016451  1
2014 Ramnath NW, van de Luijtgaarden KM, van der Pluijm I, van Nimwegen M, van Heijningen PM, Swagemakers SM, van Thiel BS, Ridwan RY, van Vliet N, Vermeij M, Hawinkels LJ, de Munck A, Dzyubachyk O, Meijering E, van der Spek P, ... ... Kanaar R, et al. Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema. Plos One. 9: e106054. PMID 25255451 DOI: 10.1371/journal.pone.0106054  1
2014 Naipal KA, Verkaik NS, Ameziane N, van Deurzen CH, Ter Brugge P, Meijers M, Sieuwerts AM, Martens JW, O'Connor MJ, Vrieling H, Hoeijmakers JH, Jonkers J, Kanaar R, de Winter JP, Vreeswijk MP, et al. Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4816-26. PMID 24963051 DOI: 10.1158/1078-0432.CCR-14-0571  1
2014 Kuzniar A, Kanaar R. PIQMIe: a web server for semi-quantitative proteomics data management and analysis. Nucleic Acids Research. 42: W100-6. PMID 24861615 DOI: 10.1093/nar/gku478  1
2014 Carvalho JF, Kanaar R. Targeting homologous recombination-mediated DNA repair in cancer. Expert Opinion On Therapeutic Targets. 18: 427-58. PMID 24491188 DOI: 10.1517/14728222.2014.882900  1
2013 Shima H, Suzuki H, Sun J, Kono K, Shi L, Kinomura A, Horikoshi Y, Ikura T, Ikura M, Kanaar R, Igarashi K, Saitoh H, Kurumizaka H, Tashiro S. Activation of the SUMO modification system is required for the accumulation of RAD51 at sites of DNA damage. Journal of Cell Science. 126: 5284-92. PMID 24046452 DOI: 10.1242/jcs.133744  1
2013 Messiaen S, Le Bras A, Duquenne C, Barroca V, Moison D, Déchamps N, Doussau M, Bauchet AL, Guerquin MJ, Livera G, Essers J, Kanaar R, Habert R, Bernardino-Sgherri J. Rad54 is required for the normal development of male and female germ cells and contributes to the maintainance of their genome integrity after genotoxic stress. Cell Death & Disease. 4: e774. PMID 23949223 DOI: 10.1038/cddis.2013.281  1
2013 Sanchez H, Kertokalio A, van Rossum-Fikkert S, Kanaar R, Wyman C. Combined optical and topographic imaging reveals different arrangements of human RAD54 with presynaptic and postsynaptic RAD51-DNA filaments. Proceedings of the National Academy of Sciences of the United States of America. 110: 11385-90. PMID 23801766 DOI: 10.1073/Pnas.1306467110  1
2013 Zelensky AN, Sanchez H, Ristic D, Vidic I, van Rossum-Fikkert SE, Essers J, Wyman C, Kanaar R. Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation. Nucleic Acids Research. 41: 6475-89. PMID 23666627 DOI: 10.1093/Nar/Gkt375  1
2013 Kikuchi K, Narita T, Pham VT, Iijima J, Hirota K, Keka IS, Mohiuddin, Okawa K, Hori T, Fukagawa T, Essers J, Kanaar R, Whitby MC, Sugasawa K, Taniguchi Y, et al. Structure-specific endonucleases xpf and mus81 play overlapping but essential roles in DNA repair by homologous recombination. Cancer Research. 73: 4362-71. PMID 23576554 DOI: 10.1158/0008-5472.CAN-12-3154  1
2013 Warmerdam DO, Brinkman EK, Marteijn JA, Medema RH, Kanaar R, Smits VA. UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway. Journal of Cell Science. 126: 1923-30. PMID 23447674 DOI: 10.1242/jcs.118265  1
2013 Bergs JW, Krawczyk PM, Borovski T, ten Cate R, Rodermond HM, Stap J, Medema JP, Haveman J, Essers J, van Bree C, Stalpers LJ, Kanaar R, Aten JA, Franken NA. Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining. Dna Repair. 12: 38-45. PMID 23237939 DOI: 10.1016/j.dnarep.2012.10.008  1
2012 Eppink B, Krawczyk PM, Stap J, Kanaar R. Hyperthermia-induced DNA repair deficiency suggests novel therapeutic anti-cancer strategies. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 28: 509-17. PMID 22834701 DOI: 10.3109/02656736.2012.695427  1
2012 Rousseau L, Etienne O, Roque T, Desmaze C, Haton C, Mouthon MA, Bernardino-Sgherri J, Essers J, Kanaar R, Boussin FD. In vivo importance of homologous recombination DNA repair for mouse neural stem and progenitor cells. Plos One. 7: e37194. PMID 22666344 DOI: 10.1371/journal.pone.0037194  1
2012 Krawczyk PM, Borovski T, Stap J, Cijsouw T, ten Cate R, Medema JP, Kanaar R, Franken NA, Aten JA. Chromatin mobility is increased at sites of DNA double-strand breaks. Journal of Cell Science. 125: 2127-33. PMID 22328517 DOI: 10.1242/jcs.089847  1
2011 Levy-Barda A, Lerenthal Y, Davis AJ, Chung YM, Essers J, Shao Z, van Vliet N, Chen DJ, Hu MC, Kanaar R, Ziv Y, Shiloh Y. Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks. Cell Cycle (Georgetown, Tex.). 10: 4300-10. PMID 22134242 DOI: 10.4161/cc.10.24.18642  1
2011 Wyman C, Lebbink J, Kanaar R. Mre11-Rad50 complex crystals suggest molecular calisthenics. Dna Repair. 10: 1066-70. PMID 21893433 DOI: 10.1016/J.Dnarep.2011.07.008  1
2011 Eppink B, Tafel AA, Hanada K, van Drunen E, Hickson ID, Essers J, Kanaar R. The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination. Dna Repair. 10: 1095-105. PMID 21885354 DOI: 10.1016/j.dnarep.2011.08.006  1
2011 Tanori M, Pasquali E, Leonardi S, Giardullo P, Di Majo V, Taccioli G, Essers J, Kanaar R, Mullenders LH, Atkinson MJ, Mancuso M, Saran A, Pazzaglia S. Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum. Oncogene. 30: 4740-9. PMID 21602895 DOI: 10.1038/onc.2011.178  1
2011 Holthausen JT, van Loenhout MT, Sanchez H, Ristic D, van Rossum-Fikkert SE, Modesti M, Dekker C, Kanaar R, Wyman C. Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques. Nucleic Acids Research. 39: 6558-67. PMID 21576230 DOI: 10.1093/nar/gkr295  1
2011 Krawczyk PM, Eppink B, Essers J, Stap J, Rodermond H, Odijk H, Zelensky A, van Bree C, Stalpers LJ, Buist MR, Soullié T, Rens J, Verhagen HJ, O'Connor MJ, Franken NA, ... ... Kanaar R, et al. Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition. Proceedings of the National Academy of Sciences of the United States of America. 108: 9851-6. PMID 21555554 DOI: 10.1073/pnas.1101053108  1
2011 Morak MJ, van Koetsveld PM, Kanaar R, Hofland LJ, van Eijck CH. Type I interferons as radiosensitisers for pancreatic cancer. European Journal of Cancer (Oxford, England : 1990). 47: 1938-45. PMID 21478011 DOI: 10.1016/j.ejca.2011.03.009  1
2011 Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, ... ... Kanaar R, et al. Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Molecular Cell. 41: 529-42. PMID 21362549 DOI: 10.1016/J.Molcel.2011.02.015  1
2011 Agarwal S, van Cappellen WA, Guénolé A, Eppink B, Linsen SE, Meijering E, Houtsmuller A, Kanaar R, Essers J. ATP-dependent and independent functions of Rad54 in genome maintenance. The Journal of Cell Biology. 192: 735-50. PMID 21357745 DOI: 10.1083/jcb.201011025  1
2011 Ristic D, Kanaar R, Wyman C. Visualizing RAD51-mediated joint molecules: implications for recombination mechanism and the effect of sequence heterology. Nucleic Acids Research. 39: 155-67. PMID 20817928 DOI: 10.1093/Nar/Gkq766  1
2011 Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, ... ... Kanaar R, et al. Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks Molecular Cell. 42: 137. DOI: 10.1016/j.molcel.2011.03.009  1
2011 Eppink B, Essers J, Kanaar R. Interplay and Quality Control of DNA Damage Repair Mechanisms Genome Organization and Function in the Cell Nucleus. 395-415. DOI: 10.1002/9783527639991.ch16  1
2010 Sun J, Oma Y, Harata M, Kono K, Shima H, Kinomura A, Ikura T, Suzuki H, Mizutani S, Kanaar R, Tashiro S. ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot. Plos One. 5: e13554. PMID 21048951 DOI: 10.1371/journal.pone.0013554  1
2010 Holthausen JT, Wyman C, Kanaar R. Regulation of DNA strand exchange in homologous recombination. Dna Repair. 9: 1264-72. PMID 20971042 DOI: 10.1016/J.Dnarep.2010.09.014  1
2010 Warmerdam DO, Kanaar R, Smits VA. Differential Dynamics of ATR-Mediated Checkpoint Regulators. Journal of Nucleic Acids. 2010. PMID 20847938 DOI: 10.4061/2010/319142  1
2010 Chu WK, Hanada K, Kanaar R, Hickson ID. BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells. Oncogene. 29: 4705-14. PMID 20531307 DOI: 10.1038/Onc.2010.214  1
2010 Sanchez H, Kanaar R, Wyman C. Molecular recognition of DNA-protein complexes: a straightforward method combining scanning force and fluorescence microscopy. Ultramicroscopy. 110: 844-51. PMID 20382478 DOI: 10.1016/J.Ultramic.2010.03.002  1
2010 De Vlaminck I, Vidic I, van Loenhout MT, Kanaar R, Lebbink JH, Dekker C. Torsional regulation of hRPA-induced unwinding of double-stranded DNA. Nucleic Acids Research. 38: 4133-42. PMID 20197317 DOI: 10.1093/nar/gkq067  1
2010 Wang H, Zhang X, Wang P, Yu X, Essers J, Chen D, Kanaar R, Takeda S, Wang Y. Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation. Nucleic Acids Research. 38: 3245-51. PMID 20150414 DOI: 10.1093/Nar/Gkq069  1
2010 Warmerdam DO, Kanaar R. Dealing with DNA damage: relationships between checkpoint and repair pathways. Mutation Research. 704: 2-11. PMID 20006736 DOI: 10.1016/j.mrrev.2009.12.001  1
2009 Soria G, Belluscio L, van Cappellen WA, Kanaar R, Essers J, Gottifredi V. DNA damage induced Pol eta recruitment takes place independently of the cell cycle phase. Cell Cycle (Georgetown, Tex.). 8: 3340-8. PMID 19806028  1
2009 Bhagwat N, Olsen AL, Wang AT, Hanada K, Stuckert P, Kanaar R, D'Andrea A, Niedernhofer LJ, McHugh PJ. XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. Molecular and Cellular Biology. 29: 6427-37. PMID 19805513 DOI: 10.1128/Mcb.00086-09  1
2009 Brugmans L, Verkaik NS, Kunen M, van Drunen E, Williams BR, Petrini JH, Kanaar R, Essers J, van Gent DC. NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication. Dna Repair. 8: 1363-70. PMID 19782649 DOI: 10.1016/J.Dnarep.2009.09.002  1
2009 Muñoz IM, Hain K, Déclais AC, Gardiner M, Toh GW, Sanchez-Pulido L, Heuckmann JM, Toth R, Macartney T, Eppink B, Kanaar R, Ponting CP, Lilley DM, Rouse J. Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Molecular Cell. 35: 116-27. PMID 19595721 DOI: 10.1016/J.Molcel.2009.06.020  1
2009 van Loenhout MT, van der Heijden T, Kanaar R, Wyman C, Dekker C. Dynamics of RecA filaments on single-stranded DNA. Nucleic Acids Research. 37: 4089-99. PMID 19429893 DOI: 10.1093/Nar/Gkp326  1
2009 Warmerdam DO, Freire R, Kanaar R, Smits VA. Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress. Cell Cycle (Georgetown, Tex.). 8: 1765-74. PMID 19411845  1
2009 van der Linden E, Sanchez H, Kinoshita E, Kanaar R, Wyman C. RAD50 and NBS1 form a stable complex functional in DNA binding and tethering. Nucleic Acids Research. 37: 1580-8. PMID 19151086 DOI: 10.1093/Nar/Gkn1072  1
2009 Kirshner M, Rathavs M, Nizan A, Essers J, Kanaar R, Shiloh Y, Barzilai A. Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair. Dna Repair. 8: 253-61. PMID 19061978 DOI: 10.1016/j.dnarep.2008.11.005  1
2009 van Mameren J, Modesti M, Kanaar R, Wyman C, Peterman EJ, Wuite GJ. Counting RAD51 proteins disassembling from nucleoprotein filaments under tension. Nature. 457: 745-8. PMID 19060884 DOI: 10.1038/Nature07581  1
2009 Budzowska M, Kanaar R. Mechanisms of dealing with DNA damage-induced replication problems. Cell Biochemistry and Biophysics. 53: 17-31. PMID 19034694 DOI: 10.1007/s12013-008-9039-y  1
2008 Medhurst AL, Warmerdam DO, Akerman I, Verwayen EH, Kanaar R, Smits VA, Lakin ND. ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage. Journal of Cell Science. 121: 3933-40. PMID 19020305 DOI: 10.1242/jcs.033688  1
2008 Krawczyk PM, Stap J, Hoebe RA, van Oven CH, Kanaar R, Aten JA. Analysis of the mobility of DNA double-strand break-containing chromosome domains in living mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 463: 309-20. PMID 18951175 DOI: 10.1007/978-1-59745-406-3_19  1
2008 Kanaar R, Wyman C. DNA repair by the MRN complex: break it to make it. Cell. 135: 14-6. PMID 18854148 DOI: 10.1016/J.Cell.2008.09.027  1
2008 van der Heijden T, Modesti M, Hage S, Kanaar R, Wyman C, Dekker C. Homologous recombination in real time: DNA strand exchange by RecA. Molecular Cell. 30: 530-8. PMID 18498754 DOI: 10.1016/J.Molcel.2008.03.010  1
2008 Wyman C, Warmerdam DO, Kanaar R. From DNA end chemistry to cell-cycle response: the importance of structure, even when it's broken. Molecular Cell. 30: 5-6. PMID 18406321 DOI: 10.1016/J.Molcel.2008.03.007  1
2008 Stap J, Krawczyk PM, Van Oven CH, Barendsen GW, Essers J, Kanaar R, Aten JA. Induction of linear tracks of DNA double-strand breaks by alpha-particle irradiation of cells. Nature Methods. 5: 261-6. PMID 18309310 DOI: 10.1038/nmeth.f.206  1
2008 Kanaar R, Wyman C, Rothstein R. Quality control of DNA break metabolism: in the 'end', it's a good thing. The Embo Journal. 27: 581-8. PMID 18285819 DOI: 10.1038/Emboj.2008.11  1
2008 Tra W, Rakhorst H, Hofer S, Kanaar R, Perez-Amodio S. Effects of radiation on tissue-engineered mucosa 8th World Biomaterials Congress 2008. 2: 1078.  1
2007 Modesti M, Budzowska M, Baldeyron C, Demmers JA, Ghirlando R, Kanaar R. RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination. Molecular Cell. 28: 468-81. PMID 17996710 DOI: 10.1016/j.molcel.2007.08.025  1
2007 Marchetti F, Essers J, Kanaar R, Wyrobek AJ. Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations. Proceedings of the National Academy of Sciences of the United States of America. 104: 17725-9. PMID 17978187 DOI: 10.1073/pnas.0705257104  1
2007 Hanada K, Budzowska M, Davies SL, van Drunen E, Onizawa H, Beverloo HB, Maas A, Essers J, Hickson ID, Kanaar R. The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nature Structural & Molecular Biology. 14: 1096-104. PMID 17934473 DOI: 10.1038/nsmb1313  1
2007 van der Heijden T, Seidel R, Modesti M, Kanaar R, Wyman C, Dekker C. Real-time assembly and disassembly of human RAD51 filaments on individual DNA molecules. Nucleic Acids Research. 35: 5646-57. PMID 17709342 DOI: 10.1093/Nar/Gkm629  1
2007 Dinant C, de Jager M, Essers J, van Cappellen WA, Kanaar R, Houtsmuller AB, Vermeulen W. Activation of multiple DNA repair pathways by sub-nuclear damage induction methods. Journal of Cell Science. 120: 2731-40. PMID 17646676 DOI: 10.1242/jcs.004523  1
2007 Modesti M, Ristic D, van der Heijden T, Dekker C, van Mameren J, Peterman EJ, Wuite GJ, Kanaar R, Wyman C. Fluorescent human RAD51 reveals multiple nucleation sites and filament segments tightly associated along a single DNA molecule. Structure (London, England : 1993). 15: 599-609. PMID 17502105 DOI: 10.1016/J.Str.2007.04.003  1
2007 Hanada K, Vermeij M, Garinis GA, de Waard MC, Kunen MG, Myers L, Maas A, Duncker DJ, Meijers C, Dietz HC, Kanaar R, Essers J. Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice. Circulation Research. 100: 738-46. PMID 17293478 DOI: 10.1161/01.Res.0000260181.19449.95  1
2007 Brugmans L, Kanaar R, Essers J. Analysis of DNA double-strand break repair pathways in mice. Mutation Research. 614: 95-108. PMID 16797606 DOI: 10.1016/j.mrfmmm.2006.01.022  1
2007 Van Der Heijden T, Moreno-Herrero F, Kanaar R, Wyman C, Dekker C. AFM tip-induced dissociation of RecA-dsDNA filaments Nano Letters. 7: 1112. DOI: 10.1021/Nl070385K  1
2007 Agarwal S, Kanaar R, Essers J. The cell biology of homologous recombination Topics in Current Genetics. 17: 381-442. DOI: 10.1007/4735_2006_0214  1
2006 Rakhorst HA, Tra WM, Posthumus-Van Sluijs ST, Hovius SE, Levendag PC, Kanaar R, Hofer SO. Quantitative analysis of radiation-induced DNA break repair in a cultured oral mucosal model. Tissue Engineering. 12: 3395-403. PMID 17518676 DOI: 10.1089/ten.2006.12.3395  1
2006 van der Heijden T, Moreno-Herrero F, Kanaar R, Wyman C, Dekker C. Comment on "Direct and real-time visualization of the disassembly of a single RecA-DNA-ATPgammaS complex using AFM imaging in fluid". Nano Letters. 6: 3000-2. PMID 17163748 DOI: 10.1021/Nl061746J  1
2006 Hanada K, Budzowska M, Modesti M, Maas A, Wyman C, Essers J, Kanaar R. The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. The Embo Journal. 25: 4921-32. PMID 17036055 DOI: 10.1038/Sj.Emboj.7601344  1
2006 Mohd-Sarip A, van der Knaap JA, Wyman C, Kanaar R, Schedl P, Verrijzer CP. Architecture of a polycomb nucleoprotein complex. Molecular Cell. 24: 91-100. PMID 17018295 DOI: 10.1016/J.Molcel.2006.08.007  1
2006 Mameren Jv, Modesti M, Kanaar R, Wyman C, Wuite GJ, Peterman EJ. Dissecting elastic heterogeneity along DNA molecules coated partly with Rad51 using concurrent fluorescence microscopy and optical tweezers. Biophysical Journal. 91: L78-80. PMID 16920830 DOI: 10.1529/Biophysj.106.089466  1
2006 Wyman C, Kanaar R. DNA double-strand break repair: all's well that ends well. Annual Review of Genetics. 40: 363-83. PMID 16895466 DOI: 10.1146/Annurev.Genet.40.110405.090451  1
2006 Eppink B, Wyman C, Kanaar R. Multiple interlinked mechanisms to circumvent DNA replication roadblocks. Experimental Cell Research. 312: 2660-5. PMID 16859683 DOI: 10.1016/J.Yexcr.2006.06.011  1
2006 Agarwal S, Tafel AA, Kanaar R. DNA double-strand break repair and chromosome translocations. Dna Repair. 5: 1075-81. PMID 16798112 DOI: 10.1016/j.dnarep.2006.05.029  1
2006 Essers J, Houtsmuller AB, Kanaar R. Analysis of DNA recombination and repair proteins in living cells by photobleaching microscopy. Methods in Enzymology. 408: 463-85. PMID 16793387 DOI: 10.1016/S0076-6879(06)08029-3  1
2006 Aten JA, Kanaar R. Chromosomal organization: mingling with the neighbors. Plos Biology. 4: e155. PMID 16683864 DOI: 10.1371/journal.pbio.0040155  1
2006 Wesoly J, Agarwal S, Sigurdsson S, Bussen W, Van Komen S, Qin J, van Steeg H, van Benthem J, Wassenaar E, Baarends WM, Ghazvini M, Tafel AA, Heath H, Galjart N, Essers J, ... ... Kanaar R, et al. Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis. Molecular and Cellular Biology. 26: 976-89. PMID 16428451 DOI: 10.1128/Mcb.26.3.976-989.2006  1
2005 Garinis GA, Mitchell JR, Moorhouse MJ, Hanada K, de Waard H, Vandeputte D, Jans J, Brand K, Smid M, van der Spek PJ, Hoeijmakers JH, Kanaar R, van der Horst GT. Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks. The Embo Journal. 24: 3952-62. PMID 16252008 DOI: 10.1038/sj.emboj.7600849  1
2005 Essers J, Theil AF, Baldeyron C, van Cappellen WA, Houtsmuller AB, Kanaar R, Vermeulen W. Nuclear dynamics of PCNA in DNA replication and repair. Molecular and Cellular Biology. 25: 9350-9. PMID 16227586 DOI: 10.1128/MCB.25.21.9350-9359.2005  1
2005 Moreno-Herrero F, de Jager M, Dekker NH, Kanaar R, Wyman C, Dekker C. Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA. Nature. 437: 440-3. PMID 16163361 DOI: 10.1038/Nature03927  1
2005 Ristic D, Modesti M, van der Heijden T, van Noort J, Dekker C, Kanaar R, Wyman C. Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function. Nucleic Acids Research. 33: 3292-302. PMID 15944450 DOI: 10.1093/Nar/Gki640  1
2005 van Veelen LR, Essers J, van de Rakt MW, Odijk H, Pastink A, Zdzienicka MZ, Paulusma CC, Kanaar R. Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52. Mutation Research. 574: 34-49. PMID 15914205 DOI: 10.1016/j.mrfmmm.2005.01.020  1
2005 van Veelen LR, Cervelli T, van de Rakt MW, Theil AF, Essers J, Kanaar R. Analysis of ionizing radiation-induced foci of DNA damage repair proteins. Mutation Research. 574: 22-33. PMID 15914204 DOI: 10.1016/j.mrfmmm.2005.01.019  1
2005 van der Heijden T, van Noort J, van Leest H, Kanaar R, Wyman C, Dekker NH, Dekker N, Dekker C. Torque-limited RecA polymerization on dsDNA. Nucleic Acids Research. 33: 2099-105. PMID 15824062 DOI: 10.1093/Nar/Gki512  1
2005 Adams DJ, van der Weyden L, Gergely FV, Arends MJ, Ng BL, Tannahill D, Kanaar R, Markus A, Morris BJ, Bradley A. BRCTx is a novel, highly conserved RAD18-interacting protein. Molecular and Cellular Biology. 25: 779-88. PMID 15632077 DOI: 10.1128/Mcb.25.2.779-788.2005  1
2005 Essers J, van Cappellen WA, Theil AF, van Drunen E, Jaspers NG, Hoeijmakers JH, Wyman C, Vermeulen W, Kanaar R. Dynamics of relative chromosome position during the cell cycle. Molecular Biology of the Cell. 16: 769-75. PMID 15574874 DOI: 10.1091/Mbc.E04-10-0876  1
2005 Beerens N, Hoeijmakers JH, Kanaar R, Vermeulen W, Wyman C. The CSB protein actively wraps DNA. The Journal of Biological Chemistry. 280: 4722-9. PMID 15548521 DOI: 10.1074/Jbc.M409147200  1
2004 Heyer WD, Kanaar R. Recombination mechanisms; fortieth anniversary meeting of the Holliday model. Molecular Cell. 16: 1-9. PMID 15469817 DOI: 10.1016/j.molcel.2004.09.025  1
2004 Budzowska M, Jaspers I, Essers J, de Waard H, van Drunen E, Hanada K, Beverloo B, Hendriks RW, de Klein A, Kanaar R, Hoeijmakers JH, Maas A. Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination. The Embo Journal. 23: 3548-58. PMID 15297881 DOI: 10.1038/sj.emboj.7600353  1
2004 Lau A, Kanaar R, Jackson SP, O'Connor MJ. Suppression of retroviral infection by the RAD52 DNA repair protein. The Embo Journal. 23: 3421-9. PMID 15297876 DOI: 10.1038/sj.emboj.7600348  1
2004 Wyman C, Kanaar R. Homologous recombination: down to the wire. Current Biology : Cb. 14: R629-31. PMID 15296782 DOI: 10.1016/J.Cub.2004.07.049  1
2004 Wyman C, Ristic D, Kanaar R. Homologous recombination-mediated double-strand break repair. Dna Repair. 3: 827-33. PMID 15279767 DOI: 10.1016/J.Dnarep.2004.03.037  1
2004 McPherson JP, Lemmers B, Chahwan R, Pamidi A, Migon E, Matysiak-Zablocki E, Moynahan ME, Essers J, Hanada K, Poonepalli A, Sanchez-Sweatman O, Khokha R, Kanaar R, Jasin M, Hande MP, et al. Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science (New York, N.Y.). 304: 1822-6. PMID 15205536 DOI: 10.1126/Science.1094557  1
2004 Niedernhofer LJ, Odijk H, Budzowska M, van Drunen E, Maas A, Theil AF, de Wit J, Jaspers NG, Beverloo HB, Hoeijmakers JH, Kanaar R. The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks. Molecular and Cellular Biology. 24: 5776-87. PMID 15199134 DOI: 10.1128/Mcb.24.13.5776-5787.2004  1
2004 Couëdel C, Mills KD, Barchi M, Shen L, Olshen A, Johnson RD, Nussenzweig A, Essers J, Kanaar R, Li GC, Alt FW, Jasin M. Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes & Development. 18: 1293-304. PMID 15175261 DOI: 10.1101/Gad.1209204  1
2004 Mills KD, Ferguson DO, Essers J, Eckersdorff M, Kanaar R, Alt FW. Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability. Genes & Development. 18: 1283-92. PMID 15175260 DOI: 10.1101/Gad.1204304  1
2004 de Jager M, Trujillo KM, Sung P, Hopfner KP, Carney JP, Tainer JA, Connelly JC, Leach DR, Kanaar R, Wyman C. Differential arrangements of conserved building blocks among homologs of the Rad50/Mre11 DNA repair protein complex. Journal of Molecular Biology. 339: 937-49. PMID 15165861 DOI: 10.1016/J.Jmb.2004.04.014  1
2004 Aten JA, Stap J, Krawczyk PM, van Oven CH, Hoebe RA, Essers J, Kanaar R. Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science (New York, N.Y.). 303: 92-5. PMID 14704429 DOI: 10.1126/science.1088845  1
2003 Abraham J, Lemmers B, Hande MP, Moynahan ME, Chahwan C, Ciccia A, Essers J, Hanada K, Chahwan R, Khaw AK, McPherson P, Shehabeldin A, Laister R, Arrowsmith C, Kanaar R, et al. Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. The Embo Journal. 22: 6137-47. PMID 14609959 DOI: 10.1093/Emboj/Cdg580  1
2003 Modesti M, Junop MS, Ghirlando R, van de Rakt M, Gellert M, Yang W, Kanaar R. Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive. Journal of Molecular Biology. 334: 215-28. PMID 14607114 DOI: 10.1016/J.Jmb.2003.09.031  1
2003 Ristic D, Modesti M, Kanaar R, Wyman C. Rad52 and Ku bind to different DNA structures produced early in double-strand break repair. Nucleic Acids Research. 31: 5229-37. PMID 12954758 DOI: 10.1093/Nar/Gkg729  1
2003 Tan TL, Kanaar R, Wyman C. Rad54, a Jack of all trades in homologous recombination. Dna Repair. 2: 787-94. PMID 12826279 DOI: 10.1016/S1568-7864(03)00070-3  1
2003 van Noort J, van Der Heijden T, de Jager M, Wyman C, Kanaar R, Dekker C. The coiled-coil of the human Rad50 DNA repair protein contains specific segments of increased flexibility. Proceedings of the National Academy of Sciences of the United States of America. 100: 7581-6. PMID 12805565 DOI: 10.1073/Pnas.1330706100  1
2003 Savouret C, Brisson E, Essers J, Kanaar R, Pastink A, te Riele H, Junien C, Gourdon G. CTG repeat instability and size variation timing in DNA repair-deficient mice. The Embo Journal. 22: 2264-73. PMID 12727892 DOI: 10.1093/emboj/cdg202  1
2003 Bross L, Wesoly J, Buerstedde JM, Kanaar R, Jacobs H. Somatic hypermutation does not require Rad54 and Rad54B-mediated homologous recombination. European Journal of Immunology. 33: 352-7. PMID 12548566 DOI: 10.1002/immu.200310009  1
2002 Essers J, Hendriks RW, Wesoly J, Beerens CE, Smit B, Hoeijmakers JH, Wyman C, Dronkert ML, Kanaar R. Analysis of mouse Rad54 expression and its implications for homologous recombination. Dna Repair. 1: 779-93. PMID 12531026 DOI: 10.1016/S1568-7864(02)00110-6  1
2002 de Jager M, Wyman C, van Gent DC, Kanaar R. DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP. Nucleic Acids Research. 30: 4425-31. PMID 12384589 DOI: 10.1093/Nar/Gkf574  1
2002 D'Avirro N, Truong D, Luong M, Kanaar R, Selsing E. Gene conversion-like sequence transfers between transgenic antibody V genes are independent of RAD54 Journal of Immunology. 169: 3069-3075. PMID 12218123 DOI: 10.4049/Jimmunol.169.6.3069  1
2002 De Jager M, Kanaar R. Genome instability and Rad50 S: Subtle yet severe Genes and Development. 16: 2173-2178. PMID 12208840 DOI: 10.1101/gad.1025402  1
2002 Difilippantonio MJ, Petersen S, Chen HT, Johnson R, Jasin M, Kanaar R, Ried T, Nussenzweig A. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification Journal of Experimental Medicine. 196: 469-480. PMID 12186839 DOI: 10.1084/Jem.20020851  1
2002 Wyman C, Kanaar R. Chromosome organization: Reaching out to embrace new models Current Biology. 12: R446-R448. PMID 12121633 DOI: 10.1016/S0960-9822(02)00941-7  1
2002 Godthelp BC, Wiegant WW, van Duijn-Goedhart A, Schärer OD, van Buul PP, Kanaar R, Zdzienicka MZ. Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Nucleic Acids Research. 30: 2172-82. PMID 12000837 DOI: 10.1093/Nar/30.10.2172  1
2002 Essers J, Houtsmuller AB, Van Veelen L, Paulusma C, Nigg AL, Pastink A, Vermeulen W, Hoeijmakers JHJ, Kanaar R. Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage Embo Journal. 21: 2030-2037. PMID 11953322 DOI: 10.1093/emboj/21.8.2030  1
2002 Kraakman-van der Zwet M, Overkamp WJ, van Lange RE, Essers J, van Duijn-Goedhart A, Wiggers I, Swaminathan S, van Buul PP, Errami A, Tan RT, Jaspers NG, Sharan SK, Kanaar R, Zdzienicka MZ. Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions. Molecular and Cellular Biology. 22: 669-79. PMID 11756561 DOI: 10.1128/MCB.22.2.669-679.2002  1
2001 De Jager M, Van Noort J, Van Gent DC, Dekker C, Kanaar R, Wyman C. Human Rad50/Mre11 is a flexible complex that can tether DNA ends Molecular Cell. 8: 1129-1135. PMID 11741547 DOI: 10.1016/S1097-2765(01)00381-1  1
2001 Niedernhofer LJ, Essers J, Weeda G, Beverloo B, De Wit J, Muijtjens M, Odijk H, Hoeijmakers JHJ, Kanaar R. The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells Embo Journal. 20: 6540-6549. PMID 11707424 DOI: 10.1093/Emboj/20.22.6540  1
2001 Dronkert MLG, Kanaar R. Repair of DNA interstrand cross-links Mutation Research - Dna Repair. 486: 217-247. PMID 11516927 DOI: 10.1016/S0921-8777(01)00092-1  1
2001 Loonstra A, Vooijs M, Beverloo HB, Allak BA, Van Drunen E, Kanaar R, Berns A, Jonkers J. Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 98: 9209-9214. PMID 11481484 DOI: 10.1073/pnas.161269798  1
2001 Ristic D, Wyman C, Paulusma C, Kanaar R. The architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNA Proceedings of the National Academy of Sciences of the United States of America. 98: 8454-8460. PMID 11459989 DOI: 10.1073/Pnas.151056798  1
2001 Modesti M, Kanaar R. Homologous recombination: From model organisms to human disease Genome Biology. 2: 1014.1-1014.5. PMID 11387040  1
2001 Modesti M, Kanaar R. Dna repair: Spot(light)s on chromatin Current Biology. 11: R229-R232. PMID 11301269 DOI: 10.1016/S0960-9822(01)00112-9  1
2001 Van Gent DC, Hoeijmakers JHJ, Kanaar R. Chromosomal stability and the DNA double-stranded break connection Nature Reviews Genetics. 2: 196-206. PMID 11256071 DOI: 10.1038/35056049  1
2001 De Jager M, Dronkert MLG, Modesti M, Beerens CEMT, Kanaar R, Van Gent DC. DNA-binding and strand-annealing activities of human Mre11: Implications for its roles in DNA double-strand break repair pathways Nucleic Acids Research. 29: 1317-1325. PMID 11238998  1
2000 Citterio E, Van Den Boom V, Schnitzler G, Kanaar R, Bonte E, Kingston RE, Hoeijmakers JH, Vermeulen W. ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor. Molecular and Cellular Biology. 20: 7643-53. PMID 11003660 DOI: 10.1128/Mcb.20.20.7643-7653.2000  1
2000 Takata M, Sasaki MS, Sonoda E, Fukushima T, Morrison C, Albala JS, Swagemakers SMA, Kanaar R, Thompson LH, Takeda S. The Rad51 paralog Rad51B promotes homologous recombinational repair Molecular and Cellular Biology. 20: 6476-6482. PMID 10938124 DOI: 10.1128/MCB.20.17.6476-6482.2000  1
2000 Dronkert MLG, De Wit J, Boeve M, Vasconcelos ML, Van Steeg H, Tan TLR, Hoeijmakers JHJ, Kanaar R. Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C Molecular and Cellular Biology. 20: 4553-4561. PMID 10848582 DOI: 10.1128/MCB.20.13.4553-4561.2000  1
2000 Dronkert ML, Beverloo HB, Johnson RD, Hoeijmakers JH, Jasin M, Kanaar R. Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange. Molecular and Cellular Biology. 20: 3147-56. PMID 10757799 DOI: 10.1128/Mcb.20.9.3147-3156.2000  1
2000 Essers J, Van Steeg H, De Wit J, Swagemakers SMA, Vermeij M, Hoeijmakers JHJ, Kanaar R. Homologous and non-homologous recombination differentially affect DNA damage repair in mice Embo Journal. 19: 1703-1710. PMID 10747037  1
1999 Bennink ML, Schärer OD, Kanaar R, Sakata-Sogawa K, Schins JM, Kanger JS, De Grooth BG, Greve J. Single-molecule manipulation of double-stranded DNA using optical tweezers: Interaction studies of DNA with RecA and YOYO-1 Cytometry. 36: 200-208. PMID 10404969 DOI: 10.1002/(SICI)1097-0320(19990701)36:3<200::AID-CYTO9>3.0.CO;2-T  1
1999 Crowder SM, Kanaar R, Rio DC, Alber T. Absence of interdomain contacts in the crystal structure of the RNA recognition motifs of Sex-lethal. Proceedings of the National Academy of Sciences of the United States of America. 96: 4892-7. PMID 10220389 DOI: 10.1073/Pnas.96.9.4892  1
1999 Tan TL, Essers J, Citterio E, Swagemakers SM, de Wit J, Benson FE, Hoeijmakers JH, Kanaar R. Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation. Current Biology : Cb. 9: 325-8. PMID 10209103 DOI: 10.1016/S0960-9822(99)80142-0  1
1999 Parisi S, McKay MJ, Molnar M, Thompson MA, van der Spek PJ, van Drunen-Schoenmaker E, Kanaar R, Lehmann E, Hoeijmakers JH, Kohli J. Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humans. Molecular and Cellular Biology. 19: 3515-28. PMID 10207075 DOI: 10.1128/Mcb.19.5.3515  1
1998 Kanaar R, Hoeijmakers JHJ, Van Gent DC. Molecular mechanisms of DNA double-strand break repair Trends in Cell Biology. 8: 483-489. PMID 9861670 DOI: 10.1016/S0962-8924(98)01383-X  1
1998 Swagemakers SMA, Essers J, De Wit J, Hoeijmakers JHJ, Kanaar R. The human Rad54 recombinational DNA repair protein is a double-stranded DNA-dependent ATPase Journal of Biological Chemistry. 273: 28292-28297. PMID 9774452 DOI: 10.1074/jbc.273.43.28292  1
1998 Rudner DZ, Breger KS, Kanaar R, Adams MD, Rio DC. RNA binding activity of heterodimeric splicing factor U2AF: at least one RS domain is required for high-affinity binding. Molecular and Cellular Biology. 18: 4004-11. PMID 9632785 DOI: 10.1128/Mcb.18.7.4004  1
1998 Rudner DZ, Kanaar R, Breger KS, Rio DC. Interaction between subunits of heterodimeric splicing factor U2AF is essential in vivo. Molecular and Cellular Biology. 18: 1765-73. PMID 9528748 DOI: 10.1128/Mcb.18.4.1765  1
1998 Kanaar R, Hoeljmakers JHJ. From competition to collaboration Nature. 391: 335-338. PMID 9450742 DOI: 10.1038/34790  1
1997 Kanaar R, Hoeijmakers JH. Recombination and joining: different means to the same ends Genes and Function. 1: 165-174. PMID 9680292  1
1997 Lee AL, Volkman BF, Robertson SA, Rudner DZ, Barbash DA, Cline TW, Kanaar R, Rio DC, Wemmer DE. Chemical shift mapping of the RNA-binding interface of the multiple-RBD protein sex-lethal. Biochemistry. 36: 14306-17. PMID 9398148 DOI: 10.1021/Bi970830Y  1
1997 Hammond LE, Rudner DZ, Kanaar R, Rio DC. Mutations in the hrp48 gene, which encodes a Drosophila heterogeneous nuclear ribonucleoprotein particle protein, cause lethality and developmental defects and affect P-element third-intron splicing in vivo. Molecular and Cellular Biology. 17: 7260-7. PMID 9372958 DOI: 10.1128/Mcb.17.12.7260  1
1997 Essers J, Hendriks RW, Swagemakers SMA, Troelstra C, De Wit J, Bootsma D, Hoeijmakers JHJ, Kanaar R. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination Cell. 89: 195-204. PMID 9108475 DOI: 10.1016/S0092-8674(00)80199-3  1
1996 Lehmann AR, Bridges BA, Hanawalt PC, Johnson RT, Kanaar R, Krokan HE, Kyrtopoulos S, Lambert B, Melton DW, Moustacchi E, Natarajan AT, Radman M, Sarasin A, Seeberg E, Smerdon MJ, et al. Workshop on processing of DNA damage. Mutation Research. 364: 245-70. PMID 8960136 DOI: 10.1016/S0921-8777(96)00037-7  1
1996 Rudner DZ, Kanaar R, Breger KS, Rio DC. Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects. Proceedings of the National Academy of Sciences of the United States of America. 93: 10333-7. PMID 8816800 DOI: 10.1073/Pnas.93.19.10333  1
1996 McKay MJ, Troelstra C, Van Der Spek P, Kanaar R, Smit B, Hagemeijer A, Bootsma D, Hoeijmakers JHJ. Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double- strand break repair gene in human and mouse Genomics. 36: 305-315. PMID 8812457 DOI: 10.1006/Geno.1996.0466  1
1996 Kanaar R, Troelstra C, Swagemakers SMA, Essers J, Smit B, Franssen JH, Pastink A, Bezzubova OY, Buerstedde JM, Clever B, Heyer WD, Hoeijmakers JHJ. Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: Evidence for functional conservation Current Biology. 6: 828-838. PMID 8805304 DOI: 10.1016/S0960-9822(02)00606-1  1
1996 Benjamin KR, Abola AP, Kanaar R, Cozzarelli NR. Contributions of supercoiling to Tn3 resolvase and phage Mu Gin site-specific recombination. Journal of Molecular Biology. 256: 50-65. PMID 8609613 DOI: 10.1006/Jmbi.1996.0067  1
1995 Kanaar R, Lee AL, Rudner DZ, Wemmer DE, Rio DC. Interaction of the sex-lethal RNA binding domains with RNA. The Embo Journal. 14: 4530-9. PMID 7556096 DOI: 10.1002/J.1460-2075.1995.Tb00132.X  1
1994 Crisona NJ, Kanaar R, Gonzalez TN, Zechiedrich EL, Klippel A, Cozzarelli NR. Processive recombination by wild-type gin and an enhancer-independent mutant. Insight into the mechanisms of recombination selectivity and strand exchange. Journal of Molecular Biology. 243: 437-57. PMID 7966272 DOI: 10.1006/Jmbi.1994.1671  1
1994 Siebel CW, Kanaar R, Rio DC. Regulation of tissue-specific P-element pre-mRNA splicing requires the RNA-binding protein PSI. Genes & Development. 8: 1713-25. PMID 7958851 DOI: 10.1101/Gad.8.14.1713  1
1994 Chen J, Kanaar R, Cozzarelli NR. The Sep1 strand exchange protein from Saccharomyces cerevisiae promotes a paranemic joint between homologous DNA molecules. Genes & Development. 8: 1356-66. PMID 7926736 DOI: 10.1101/Gad.8.11.1356  1
1993 Klippel A, Kanaar R, Kahmann R, Cozzarelli NR. Analysis of strand exchange and DNA binding of enhancer-independent Gin recombinase mutants. The Embo Journal. 12: 1047-57. PMID 8384550 DOI: 10.1002/J.1460-2075.1993.Tb05746.X  1
1993 Kanaar R, Roche SE, Beall EL, Green MR, Rio DC. The conserved pre-mRNA splicing factor U2AF from Drosophila: requirement for viability. Science (New York, N.Y.). 262: 569-73. PMID 7692602  1
1992 Kanaar R, Cozzarelli NR. Roles of supercoiled DNA structure in DNA transactions Current Opinion in Structural Biology. 2: 369-379. DOI: 10.1016/0959-440X(92)90227-X  1
1990 Kanaar R, Klippel A, Shekhtman E, Dungan JM, Kahmann R, Cozzarelli NR. Processive recombination by the phage Mu Gin system: implications for the mechanisms of DNA strand exchange, DNA site alignment, and enhancer action. Cell. 62: 353-66. PMID 2164890 DOI: 10.1016/0092-8674(90)90372-L  1
1989 Kanaar R, van Hal JP, van de Putte P. The recombinational enhancer for DNA inversion functions independent of its orientation as a consequence of dyad symmetry in the Fis-DNA complex. Nucleic Acids Research. 17: 6043-53. PMID 2549506 DOI: 10.1093/nar/17.15.6043  1
1989 Kanaar R, van de Putte P, Cozzarelli NR. Gin-mediated recombination of catenated and knotted DNA substrates: implications for the mechanism of interaction between cis-acting sites. Cell. 58: 147-59. PMID 2546671 DOI: 10.1016/0092-8674(89)90411-X  1
1988 Kanaar R, van de Putte P, Cozzarelli NR. Gin-mediated DNA inversion: product structure and the mechanism of strand exchange. Proceedings of the National Academy of Sciences of the United States of America. 85: 752-6. PMID 2829201 DOI: 10.1073/Pnas.85.3.752  1
1987 Kanaar R, van de Putte P. Topological aspects of site-specific DNA-inversion. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 7: 195-200. PMID 3325048 DOI: 10.1002/Bies.950070502  1
1986 Kanaar R, van de Putte P, Cozzarelli NR. Purification of the Gin recombination protein of Escherichia coli phage Mu and its host factor. Biochimica Et Biophysica Acta. 866: 170-7. PMID 3006776 DOI: 10.1016/0167-4781(86)90114-4  1
1984 Plasterk RH, Kanaar R, van de Putte P. A genetic switch in vitro: DNA inversion by Gin protein of phage Mu. Proceedings of the National Academy of Sciences of the United States of America. 81: 2689-92. PMID 6232613 DOI: 10.1073/Pnas.81.9.2689  1
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