Year |
Citation |
Score |
2014 |
Hou Z, Wilson MR, Wilson L, Desmoulin SK, Huang J, Matherly LH. Abstract 783: Identification of structural determinants of human proton-coupled folate transporter oligomerization Cancer Research. 74: 783-783. DOI: 10.1158/1538-7445.Am2014-783 |
0.643 |
|
2012 |
Desmoulin SK, Hou Z, Gangjee A, Matherly LH. The human proton-coupled folate transporter: Biology and therapeutic applications to cancer. Cancer Biology & Therapy. 13: 1355-73. PMID 22954694 DOI: 10.4161/Cbt.22020 |
0.667 |
|
2012 |
Desmoulin SK, Wang L, Polin L, White K, Kushner J, Stout M, Hou Z, Cherian C, Gangjee A, Matherly LH. Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporter. Molecular Pharmacology. 82: 591-600. PMID 22740639 DOI: 10.1124/Mol.112.079004 |
0.672 |
|
2012 |
Hou Z, Desmoulin SK, Etnyre E, Olive M, Hsiung B, Cherian C, Wloszczynski PA, Moin K, Matherly LH. Identification and functional impact of homo-oligomers of the human proton-coupled folate transporter Journal of Biological Chemistry. 287: 4982-4995. PMID 22179615 DOI: 10.1074/Jbc.M111.306860 |
0.674 |
|
2012 |
Cherian C, Desmoulin SK, Wang L, Polin L, White K, Kushner J, Stout M, Hou Z, Gangjee A, Matherly LH. Abstract 3826: Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter Cancer Research. 72: 3826-3826. DOI: 10.1158/1538-7445.Am2012-3826 |
0.729 |
|
2012 |
Desmoulin SK, Wang L, Polin L, White K, Kushner J, Stout M, Hou Z, Cherian C, Gangjee A, Matherly LH. Abstract 3825: The impact of the reduced folate carrier on the collateral sensitivity of novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolates with selective uptake by the proton-coupled folate transporter Cancer Research. 72: 3825-3825. DOI: 10.1158/1538-7445.Am2012-3825 |
0.682 |
|
2011 |
Wang L, Desmoulin SK, Cherian C, Polin L, White K, Kushner J, Fulterer A, Chang MH, Mitchell-Ryan S, Stout M, Romero MF, Hou Z, Matherly LH, Gangjee A. Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase. Journal of Medicinal Chemistry. 54: 7150-64. PMID 21879757 DOI: 10.1021/Jm200739E |
0.663 |
|
2011 |
Wang Y, Mitchell S, Cherian C, Desmoulin SK, Hou Z, Kisliuk RL, Matherly LH, Gangjee A. Abstract 3250: Design, synthesis and biological evaluation of side chain pemetrexed (PMX) analogues as potent inhibitors of tumors expressing folate receptors via GARFTase inhibition Cancer Research. 71: 3250-3250. DOI: 10.1158/1538-7445.Am2011-3250 |
0.726 |
|
2011 |
Desmoulin SK, Wang L, Tait L, Polin L, Hou Z, Cherian C, Gangjee A, Matherly LH. Abstract 2528: Therapeutic targeting of a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by PCFT Cancer Research. 71: 2528-2528. DOI: 10.1158/1538-7445.Am2011-2528 |
0.723 |
|
2011 |
Wang L, Cherian C, Desmoulin SK, Hou Z, Matherly LH, Gangjee A. Abstract 1364: Design, synthesis and evaluation of potent antiproliferative and cytotoxic antifolates with selective FRs and PCFT transport over RFC and potent GARFTase inhibition Cancer Research. 71: 1364-1364. DOI: 10.1158/1538-7445.Am2011-1364 |
0.676 |
|
2010 |
Desmoulin SK, Wang Y, Wu J, Stout M, Hou Z, Fulterer A, Chang MH, Romero MF, Cherian C, Gangjee A, Matherly LH. Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumors. Molecular Pharmacology. 78: 577-87. PMID 20601456 DOI: 10.1124/Mol.110.065896 |
0.707 |
|
2010 |
Wang L, Cherian C, Desmoulin SK, Polin L, Deng Y, Wu J, Hou Z, White K, Kushner J, Matherly LH, Gangjee A. Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry. Journal of Medicinal Chemistry. 53: 1306-18. PMID 20085328 DOI: 10.1021/Jm9015729 |
0.696 |
|
2010 |
Gangjee A, Wang L, Cherian C, Desmoulin SK, Hou Z, Kisliuk RL, Matherly LH. Abstract 4542: The design, synthesis andin vitroevaluation of selective FR α and β and PCFT substrates with potent GARFTase inhibitory activity as antitumor agents Cancer Research. 70: 4542-4542. DOI: 10.1158/1538-7445.Am10-4542 |
0.645 |
|
2008 |
Wang Z, Desmoulin S, Banerjee S, Kong D, Li Y, Deraniyagala RL, Abbruzzese J, Sarkar FH. Synergistic effects of multiple natural products in pancreatic cancer cells. Life Sciences. 83: 293-300. PMID 18640131 DOI: 10.1016/J.Lfs.2008.06.017 |
0.36 |
|
Show low-probability matches. |