Samuel L. Murphy, Ph.D. - Publications

Affiliations: 
2004 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Microbiology Biology, Cell Biology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Mingozzi F, Chen Y, Murphy SL, Edmonson SC, Tai A, Price SD, Metzger ME, Zhou S, Wright JF, Donahue RE, Dunbar CE, High KA. Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1410-6. PMID 22565846 DOI: 10.1038/Mt.2012.84  0.324
2011 Li H, Haurigot V, Doyon Y, Li T, Wong SY, Bhagwat AS, Malani N, Anguela XM, Sharma R, Ivanciu L, Murphy SL, Finn JD, Khazi FR, Zhou S, Paschon DE, et al. In vivo genome editing restores haemostasis in a mouse model of haemophilia. Nature. 475: 217-21. PMID 21706032 DOI: 10.1038/Nature10177  0.315
2010 Rozmyslowicz T, Murphy SL, Conover DO, Gaulton GN. HIV-1 infection inhibits cytokine production in human thymic macrophages. Experimental Hematology. 38: 1157-66. PMID 20817073 DOI: 10.1016/J.Exphem.2010.08.009  0.588
2010 Li H, Haurigot V, Doyon Y, Li J, Bhagwat A, Wong S, Anguela X, Sharma R, Ivanciu L, Murphy S, Zhou S, Paschon D, Rebar E, Gregory PD, Holmes MC, et al. Phenotypic Correction of a Mouse Model of Hemophilia B by In Vivo Genetic Correction of the F9 Gene Blood. 116: LBA-5-LBA-5. DOI: 10.1182/Blood.V116.21.Lba-5.Lba-5  0.332
2009 Pien GC, Basner-Tschakarjan E, Hui DJ, Mentlik AN, Finn JD, Hasbrouck NC, Zhou S, Murphy SL, Maus MV, Mingozzi F, Orange JS, High KA. Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors. The Journal of Clinical Investigation. 119: 1688-95. PMID 19436115 DOI: 10.1172/Jci36891  0.411
2009 Hauck B, Murphy SL, Smith PH, Qu G, Liu X, Zelenaia O, Mingozzi F, Sommer JM, High KA, Wright JF. Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 144-52. PMID 18941440 DOI: 10.1038/Mt.2008.227  0.383
2008 Murphy SL, Bhagwat A, Edmonson S, Zhou S, High KA. High-throughput screening and biophysical interrogation of hepatotropic AAV. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1960-7. PMID 18827805 DOI: 10.1038/Mt.2008.210  0.311
2008 Murphy SL, Li H, Zhou S, Schlachterman A, High KA, High K. Prolonged susceptibility to antibody-mediated neutralization for adeno-associated vectors targeted to the liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 138-45. PMID 17955024 DOI: 10.1038/Sj.Mt.6300334  0.36
2007 Murphy SL, Gaulton GN. TR1.3 viral pathogenesis and syncytium formation are linked to Env-Gag cooperation. Journal of Virology. 81: 10777-85. PMID 17634219 DOI: 10.1128/Jvi.00816-07  0.637
2007 Mingozzi F, Maus MV, Hui DJ, Sabatino DE, Murphy SL, Rasko JE, Ragni MV, Manno CS, Sommer J, Jiang H, Pierce GF, Ertl HC, High KA. CD8(+) T-cell responses to adeno-associated virus capsid in humans. Nature Medicine. 13: 419-22. PMID 17369837 DOI: 10.1038/Nm1549  0.439
2007 Li H, Murphy SL, Giles-Davis W, Edmonson S, Xiang Z, Li Y, Lasaro MO, High KA, Ertl HC. Pre-existing AAV capsid-specific CD8+ T cells are unable to eliminate AAV-transduced hepatocytes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 792-800. PMID 17245353 DOI: 10.1038/Sj.Mt.6300090  0.418
2007 Hauck B, Murphy S, Lui X, Zelenaia O, High KA, Wright JF. Trace Capsid DNA Impurities in AAV2 Vectors Are Not Transcribed and Are Unlikely To Contribute to Capsid Peptide-MHC Class I Complexes Blood. 110: 3736-3736. DOI: 10.1182/Blood.V110.11.3736.3736  0.368
2006 Murphy SL, Chung-Landers M, Honczarenko M, Gaulton GN. Linkage of reduced receptor affinity and superinfection to pathogenesis of TR1.3 murine leukemia virus. Journal of Virology. 80: 4601-9. PMID 16611920 DOI: 10.1128/Jvi.80.9.4601-4609.2006  0.624
2006 Murphy SL, Hui DJ, Edmonson S, High KA. Conserved Amino Acid Sequences in Parvovirus B19 and Adeno-Associated Virus Stimulate Functionally Cross-Reactive CD8 T Cells. Blood. 108: 3269-3269. DOI: 10.1182/Blood.V108.11.3269.3269  0.421
2006 Murphy SL, Sabatino D, Mingozzi F, Edmonson S, High K. 74. Cellular Immunity to Adeno-Associated Virus Capsid Attenuates Transgene Expression in the Liver Molecular Therapy. 13: S31-S32. DOI: 10.1016/J.Ymthe.2006.08.091  0.385
2005 Lin G, Murphy SL, Gaulton GN, Hoxie JA. Modification of a viral envelope glycoprotein cell-cell fusion assay by utilizing plasmid encoded bacteriophage RNA polymerase. Journal of Virological Methods. 128: 135-42. PMID 15941597 DOI: 10.1016/J.Jviromet.2005.04.011  0.649
2004 Murphy SL, Honczarenko MJ, Dugger NV, Hoffman PM, Gaulton GN. Disparate regions of envelope protein regulate syncytium formation versus spongiform encephalopathy in neurological disease induced by murine leukemia virus TR. Journal of Virology. 78: 8392-9. PMID 15254211 DOI: 10.1128/Jvi.78.15.8392-8399.2004  0.6
2003 Rozmyslowicz T, Majka M, Kijowski J, Murphy SL, Conover DO, Poncz M, Ratajczak J, Gaulton GN, Ratajczak MZ. Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV. Aids (London, England). 17: 33-42. PMID 12478067 DOI: 10.1097/00002030-200301030-00006  0.622
1999 Majka M, Rozmyslowicz T, Lee B, Murphy SL, Pietrzkowski Z, Gaulton GN, Silberstein L, Ratajczak MZ. Bone marrow CD34(+) cells and megakaryoblasts secrete beta-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV. The Journal of Clinical Investigation. 104: 1739-49. PMID 10606628 DOI: 10.1172/Jci7779  0.62
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