Robert A. Hromas - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry, Molecular Biology, Immunology

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, ... ... Hromas RA, et al. EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair. Plos Genetics. 11: e1005675. PMID 26684013 DOI: 10.1371/Journal.Pgen.1005675  0.88
2014 Shanmugam I, Abbas M, Ayoub F, Mirabal S, Bsaili M, Caulder EK, Weinstock DM, Tomkinson AE, Hromas R, Shaheen M. Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination. The Journal of Biological Chemistry. 289: 22739-48. PMID 24923443 DOI: 10.1074/Jbc.M114.550459  0.88
2014 Cogle CR, Goldman DC, Madlambayan GJ, Leon RP, Al Masri A, Clark HA, Asbaghi SA, Tyner JW, Dunlap J, Fan G, Kovacsovics T, Liu Q, Meacham A, Hamlin KL, Hromas RA, et al. Functional integration of acute myeloid leukemia into the vascular niche. Leukemia. 28: 1978-87. PMID 24637335 DOI: 10.1038/Leu.2014.109  0.88
2014 Libby E, Garcia D, Quintana D, Fekrazad MH, Bauman J, Ebaid A, Hromas R, Rabinowitz I, Wiggins C. Disease-specific survival for patients with multiple myeloma: Significant improvements over time in all age groups Leukemia and Lymphoma. 55: 2850-2857. PMID 24588734 DOI: 10.3109/10428194.2014.897700  0.88
2013 Mohapatra S, Yannone SM, Lee SH, Hromas RA, Akopiants K, Menon V, Ramsden DA, Povirk LF. Trimming of damaged 3' overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases. Dna Repair. 12: 422-32. PMID 23602515 DOI: 10.1016/J.Dnarep.2013.03.005  0.88
2012 Hromas R, Abkowitz JL, Keating A. Facing the NIH funding crisis: how professional societies can help. Jama. 308: 2343-4. PMID 23183908 DOI: 10.1001/Jama.2012.45067  0.88
2012 Williamson EA, Damiani L, Leitao A, Hu C, Hathaway H, Oprea T, Sklar L, Shaheen M, Bauman J, Wang W, Nickoloff JA, Lee SH, Hromas R. Targeting the transposase domain of the DNA repair component metnase to enhance chemotherapy Cancer Research. 72: 6200-6208. PMID 23090115 DOI: 10.1158/0008-5472.Can-12-0313  0.88
2012 Hromas R, Williamson EA, Fnu S, Lee YJ, Park SJ, Beck BD, You JS, Leitao A, Laitao A, Nickoloff JA, Lee SH. Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart. Oncogene. 31: 4245-54. PMID 22231448 DOI: 10.1038/Onc.2011.586  0.88
2011 Oprea TI, Bauman JE, Bologa CG, Buranda T, Chigaev A, Edwards BS, Jarvik JW, Gresham HD, Haynes MK, Hjelle B, Hromas R, Hudson L, Mackenzie DA, Muller CY, Reed JC, et al. Drug Repurposing from an Academic Perspective. Drug Discovery Today. Therapeutic Strategies. 8: 61-69. PMID 22368688 DOI: 10.1016/J.Ddstr.2011.10.002  0.88
2011 Ponder J, Yoo BH, Abraham AD, Li Q, Ashley AK, Amerin CL, Zhou Q, Reid BG, Reigan P, Hromas R, Nickoloff JA, LaBarbera DV. Neoamphimedine circumvents metnase-enhanced DNA topoisomerase IIα activity through ATP-competitive inhibition. Marine Drugs. 9: 2397-408. PMID 22163192 DOI: 10.3390/Md9112397  0.88
2011 Beck BD, Lee SS, Williamson E, Hromas RA, Lee SH. Biochemical characterization of metnase's endonuclease activity and its role in NHEJ repair. Biochemistry. 50: 4360-70. PMID 21491884 DOI: 10.1021/Bi200333K  0.88
2010 Wiggins CL, Harlan LC, Nelson HE, Stevens JL, Willman CL, Libby EN, Hromas RA. Age disparity in the dissemination of imatinib for treating chronic myeloid leukemia. The American Journal of Medicine. 123: 764.e1-9. PMID 20670732 DOI: 10.1016/J.Amjmed.2010.03.018  0.88
2010 Wray J, Williamson EA, Chester S, Farrington J, Sterk R, Weinstock DM, Jasin M, Lee SH, Nickoloff JA, Hromas R. The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations. Cancer Genetics and Cytogenetics. 200: 184-90. PMID 20620605 DOI: 10.1016/J.Cancergencyto.2010.04.011  0.88
2010 De Haro LP, Wray J, Williamson EA, Durant ST, Corwin L, Gentry AC, Osheroff N, Lee SH, Hromas R, Nickoloff JA. Metnase promotes restart and repair of stalled and collapsed replication forks. Nucleic Acids Research. 38: 5681-91. PMID 20457750 DOI: 10.1093/Nar/Gkq339  0.88
2010 Beck BD, Lee SS, Hromas R, Lee SH. Regulation of Metnase's TIR binding activity by its binding partner, Pso4. Archives of Biochemistry and Biophysics. 498: 89-94. PMID 20416268 DOI: 10.1016/J.Abb.2010.04.011  0.88
2010 Nelson RP, Yu M, Schwartz JE, Robertson MJ, Hromas R, Fausel CA, Vance GH, Dlouhy SR, Baute JA, Cox EA, Wood LL, Srivastava S, Robertson KA, Haut PR, Farag SS, et al. Long-term disease-free survival after nonmyeloablative cyclophosphamide/fludarabine conditioning and related/unrelated allotransplantation for acute myeloid leukemia/myelodysplasia. Bone Marrow Transplantation. 45: 1300-8. PMID 20062092 DOI: 10.1038/Bmt.2009.348  0.88
2009 Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, et al. Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Molecular and Cellular Biology. 29: 5911-22. PMID 19704007 DOI: 10.1128/Mcb.00558-09  0.88
2009 Wray J, Williamson EA, Royce M, Shaheen M, Beck BD, Lee SH, Nickoloff JA, Hromas R. Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells. Plos One. 4: e5323. PMID 19390626 DOI: 10.1371/Journal.Pone.0005323  0.88
2008 Williamson EA, Rasila KK, Corwin LK, Wray J, Beck BD, Severns V, Mobarak C, Lee SH, Nickoloff JA, Hromas R. The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation. Nucleic Acids Research. 36: 5822-31. PMID 18790802 DOI: 10.1093/Nar/Gkn560  0.88
2008 Hromas R, Wray J, Lee SH, Martinez L, Farrington J, Corwin LK, Ramsey H, Nickoloff JA, Williamson EA. The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining. Dna Repair. 7: 1927-37. PMID 18773976 DOI: 10.1016/J.Dnarep.2008.08.002  0.4
2008 Beck BD, Park SJ, Lee YJ, Roman Y, Hromas RA, Lee SH. Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair. The Journal of Biological Chemistry. 283: 9023-30. PMID 18263876 DOI: 10.1074/Jbc.M800150200  0.88
2008 Guo Y, Mantel C, Hromas RA, Broxmeyer HE. Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells (Dayton, Ohio). 26: 30-4. PMID 17932422 DOI: 10.1634/Stemcells.2007-0401  0.88
2007 Berwick M, Satagopan JM, Ben-Porat L, Carlson A, Mah K, Henry R, Diotti R, Milton K, Pujara K, Landers T, Dev Batish S, Morales J, Schindler D, Hanenberg H, Hromas R, et al. Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer. Cancer Research. 67: 9591-6. PMID 17909071 DOI: 10.1158/0008-5472.Can-07-1501  0.88
2007 Roman Y, Oshige M, Lee YJ, Goodwin K, Georgiadis MM, Hromas RA, Lee SH. Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity. Biochemistry. 46: 11369-76. PMID 17877369 DOI: 10.1021/Bi7005477  0.88
2006 Starnes T, Rasila KK, Robertson MJ, Brahmi Z, Dahl R, Christopherson K, Hromas R. The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: implications for the downregulation of CXCL14 in malignancy. Experimental Hematology. 34: 1101-5. PMID 16863917 DOI: 10.1016/J.Exphem.2006.05.015  0.88
2006 Chan RJ, Hromas R, Yoder MC. The role of Hex in hemangioblast and hematopoietic development. Methods in Molecular Biology (Clifton, N.J.). 330: 123-33. PMID 16846021 DOI: 10.1385/1-59745-036-7:123  0.88
2005 Lee SH, Oshige M, Durant ST, Rasila KK, Williamson EA, Ramsey H, Kwan L, Nickoloff JA, Hromas R. The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair. Proceedings of the National Academy of Sciences of the United States of America. 102: 18075-80. PMID 16332963 DOI: 10.1073/Pnas.0503676102  0.4
2005 Juric D, Sale S, Hromas RA, Yu R, Wang Y, Duran GE, Tibshirani R, Einhorn LH, Sikic BI. Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures. Proceedings of the National Academy of Sciences of the United States of America. 102: 17763-8. PMID 16306258 DOI: 10.1073/Pnas.0509082102  0.88
2005 Chan EM, Comer EM, Brown FC, Richkind KE, Holmes ML, Chong BH, Shiffman R, Zhang DE, Slovak ML, Willman CL, Noguchi CT, Li Y, Heiber DJ, Kwan L, Chan RJ, ... ... Hromas RA, et al. AML1-FOG2 fusion protein in myelodysplasia. Blood. 105: 4523-6. PMID 15705784 DOI: 10.1182/Blood-2004-07-2762  0.88
2005 Hou YH, Srour EF, Ramsey H, Dahl R, Broxmeyer HE, Hromas R. Identification of a human B-cell/myeloid common progenitor by the absence of CXCR4. Blood. 105: 3488-92. PMID 15650059 DOI: 10.1182/Blood-2004-07-2839  0.4
2004 Ramsey H, Christopherson K, Hromas R. Forced expression of AML1-AMP19, a fusion transcript generated from a radiation-associated t(19;21) leukemia, blocks myeloid differentiation. Leukemia Research. 28: 863-8. PMID 15203284 DOI: 10.1016/J.Leukres.2003.12.011  0.88
2004 Christopherson KW, Hromas RA. Endothelial chemokines in autoimmune disease. Current Pharmaceutical Design. 10: 145-54. PMID 14754394 DOI: 10.2174/1381612043453405  0.88
2003 Christopherson KW, Hood AF, Travers JB, Ramsey H, Hromas RA. Endothelial induction of the T-cell chemokine CCL21 in T-cell autoimmune diseases. Blood. 101: 801-6. PMID 12393410 DOI: 10.1182/Blood-2002-05-1586  0.88
2002 Mack DL, Leibowitz DS, Cooper S, Ramsey H, Broxmeyer HE, Hromas R. Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development Immunology. 107: 444-451. PMID 12460189 DOI: 10.1046/J.1365-2567.2002.01523.X  0.88
2002 Humphreys TL, Schnizlein-Bick CT, Katz BP, Baldridge LA, Hood AF, Hromas RA, Spinola SM. Evolution of the cutaneous immune response to experimental Haemophilus ducreyi infection and its relevance to HIV-1 acquisition. Journal of Immunology (Baltimore, Md. : 1950). 169: 6316-23. PMID 12444138 DOI: 10.4049/Jimmunol.169.11.6316  0.88
2002 Robertson MJ, Pelloso D, Abonour R, Hromas RA, Nelson RP, Wood L, Cornetta K. Interleukin 12 immunotherapy after autologous stem cell transplantation for hematological malignancies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3383-93. PMID 12429625  0.88
2002 Hromas R, Cooper S, Broxmeyer HE. The chemokine CCL21 protects normal marrow progenitors from ara-C cytotoxicity Cancer Chemotherapy and Pharmacology. 50: 163-166. PMID 12172984 DOI: 10.1007/S00280-002-0486-7  0.88
2002 Christopherson KW, Campbell JJ, Travers JB, Hromas RA. Low-molecular-weight heparins inhibit CCL21-induced T cell adhesion and migration. The Journal of Pharmacology and Experimental Therapeutics. 302: 290-5. PMID 12065729 DOI: 10.1124/Jpet.302.1.290  0.88
2001 Christopherson KW, Campbell JJ, Hromas RA. Transgenic overexpression of the CC chemokine CCL21 disrupts T-cell migration. Blood. 98: 3562-8. PMID 11739157 DOI: 10.1182/Blood.V98.13.3562  0.88
2001 Christopherson K, Hromas R. Chemokine regulation of normal and pathologic immune responses. Stem Cells (Dayton, Ohio). 19: 388-96. PMID 11553847 DOI: 10.1634/Stemcells.19-5-388  0.88
2000 Abonour R, Williams DA, Einhorn L, Hall KM, Chen J, Coffman J, Traycoff CM, Bank A, Kato I, Ward M, Williams SD, Hromas R, Robertson MJ, Smith FO, Woo D, et al. Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nature Medicine. 6: 652-8. PMID 10835681 DOI: 10.1038/76225  0.88
2000 Robertson MJ, Williams BT, Christopherson K, Brahmi Z, Hromas R. Regulation of human natural killer cell migration and proliferation by the exodus subfamily of CC chemokines. Cellular Immunology. 199: 8-14. PMID 10675270 DOI: 10.1006/Cimm.1999.1601  0.88
1999 Topcu Z, Mack DL, Hromas RA, Borden KL. The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control. Oncogene. 18: 7091-100. PMID 10597310 DOI: 10.1038/Sj.Onc.1203201  0.88
1999 Christopherson K, Brahmi Z, Hromas R. Regulation of naïve fetal T-cell migration by the chemokines Exodus-2 and Exodus-3. Immunology Letters. 69: 269-73. PMID 10482362 DOI: 10.1016/S0165-2478(99)00099-1  0.88
1999 Hromas R, Ye H, Spinella M, Dmitrovsky E, Xu D, Costa RH. Genesis, a Winged Helix transcriptional repressor, has embryonic expression limited to the neural crest, and stimulates proliferation in vitro in a neural development model. Cell and Tissue Research. 297: 371-82. PMID 10460485 DOI: 10.1007/S004410051365  0.88
1999 Broxmeyer HE, Kim CH, Cooper SH, Hangoc G, Hromas R, Pelus LM. Effects of CC, CXC, C, and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced chemotaxis of progenitors Annals of the New York Academy of Sciences. 872: 142-163. PMID 10372118 DOI: 10.1111/J.1749-6632.1999.Tb08460.X  0.88
1999 Hromas R, Broxmeyer HE, Kim C, Christopherson K, Hou YH. Isolation of ALP, a novel divergent murine CC chemokine with a unique carboxy terminal extension. Biochemical and Biophysical Research Communications. 258: 737-40. PMID 10329455 DOI: 10.1006/Bbrc.1999.0507  0.88
1999 Hromas R, Broxmeyer HE, Kim C, Nakshatri H, Christopherson K, Azam M, Hou YH. Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells. Biochemical and Biophysical Research Communications. 255: 703-6. PMID 10049774 DOI: 10.1006/Bbrc.1999.0257  0.88
1997 Hromas R, Hufford M, Sutton J, Xu D, Li Y, Lu L. PLAB, a novel placental bone morphogenetic protein Biochimica Et Biophysica Acta - Gene Structure and Expression. 1354: 40-44. PMID 9375789 DOI: 10.1016/S0167-4781(97)00122-X  0.88
1997 Broun ER, Nichols CR, Gize G, Cornetta K, Hromas RA, Schacht B, Einhorn LH. Tandem high dose chemotherapy with autologous bone marrow transplantation for initial relapse of testicular germ cell cancer Cancer. 79: 1605-1610. PMID 9118046 DOI: 10.1002/(Sici)1097-0142(19970415)79:8<1605::Aid-Cncr25>3.0.Co;2-0  0.88
1996 Hoffman SM, Hromas R, Amemiya C, Mohrenweiser HW. The location of MZF-1 at the telomere of human chromosome 19q makes it vulnerable to degeneration in aging cells. Leukemia Research. 20: 281-3. PMID 8637224 DOI: 10.1016/0145-2126(95)00158-1  0.88
1996 Hromas R, Davis B, Rauscher FJ, Klemsz M, Tenen D, Hoffman S, Xu D, Morris JF. Hematopoietic transcriptional regulation by the myeloid zinc finger gene, MZF-1 Current Topics in Microbiology and Immunology. 211: 158-164. PMID 8585946 DOI: 10.1007/978-3-642-85232-9_16  0.88
1995 Hromas R, Costa R. The hepatocyte nuclear factor-3/forkhead transcription regulatory family in development, inflammation, and neoplasia Critical Reviews in Oncology and Hematology. 20: 129-140. PMID 7576194 DOI: 10.1016/1040-8428(94)00151-I  0.88
1994 Broun ER, Wheat JL, Kneebone PH, Sundblad K, Hromas RA, Tricot G. Randomized trial of the addition of gram-positive prophylaxis to standard antimicrobial prophylaxis for patients undergoing autologous bone marrow transplantation. Antimicrobial Agents and Chemotherapy. 38: 576-9. PMID 8203857 DOI: 10.1128/Aac.38.3.576  0.88
1994 Morris JF, Hromas R, Rauscher FJ. Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1: Two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich core Molecular and Cellular Biology. 14: 1786-1795. PMID 8114711  0.88
1994 Derigs HG, Reifel-Miller A, Kaushansky K, Hromas RA, Boswell HS. Granulocyte-macrophage colony-stimulating factor expression is regulated at transcriptional and posttranscriptional levels in a murine bone marrow stromal cell line Experimental Hematology. 22: 924-932. PMID 8062890  0.88
1993 Hromas R, May W, Denny C, Raskind W, Moore J, Maki RA, Beck E, Klemsz MJ. Human FLI-1 localizes to chromosome 11Q24 and has an aberrant transcript in neuroepithelioma. Biochimica Et Biophysica Acta. 1172: 155-8. PMID 8439553 DOI: 10.1016/0167-4781(93)90283-J  0.88
1991 Hromas R, Collins S, Raskind W, Deaven L, Kaushansky K. Hem-1, a potential membrane protein, with expression restricted to blood cells Bba - Gene Structure and Expression. 1090: 241-244. PMID 1932118 DOI: 10.1016/0167-4781(91)90109-Y  0.88
1991 Bavisotto L, Kaushansky K, Lin N, Hromas R. Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro Journal of Experimental Medicine. 174: 1097-1101. PMID 1719120  0.88
1990 Shoemaker SG, Hromas R, Kaushansky K. Transcriptional regulation of interleukin 3 gene expression in T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 87: 9650-4. PMID 2263617 DOI: 10.1073/Pnas.87.24.9650  0.88
1987 Hromas RA, Andrews PA, Murphy MP, Burns CP. Glutathione depletion reverses cisplatin resistance in murine L1210 leukemia cells Cancer Letters. 34: 9-13. PMID 3802072 DOI: 10.1016/0304-3835(87)90067-X  0.88
1987 Hromas RA, North JA, Burns CP. Decreased cisplatin uptake by resistant L1210 leukemia cells Cancer Letters. 36: 197-201. PMID 3621151 DOI: 10.1016/0304-3835(87)90091-7  0.88
1986 Hromas RA, Yung WA. Anguidine potentiates cis-platinum in human brain tumor cells Journal of Neuro-Oncology. 3: 343-348. PMID 3958780 DOI: 10.1007/BF00165584  0.88
1985 Hromas RA, Srigley J, Murray JL. Clinical and pathological comparison of young adult women with hepatocellular carcinoma with and without exposure to oral contraceptives American Journal of Gastroenterology. 80: 479-485. PMID 2408465 DOI: 10.1111/j.1572-0241.1985.tb02150.x  0.88
1985 Hromas RA, Barlogie B, Meyn RE. Diverse mechanisms and methods of overcoming cis-platinum resistance in L1210 leukemia cells Proceedings of the American Association For Cancer Research 0.88
1984 Hromas RA, Murray JL. Bone marrow in the acquired immunodeficiency syndrome Annals of Internal Medicine. 101: 877. PMID 6497203 DOI: 10.7326/0003-4819-101-6-877_1  0.88
1981 Hromas RA, Hutchins JT, Markel DE, Scholes VE. Flow cytometric analysis of the effect of ara-C on the chronobiology of bone marrow DNA synthesis Chronobiologia. 8: 369-373. PMID 7327056  0.88
1980 Hromas RA, Markel DE, Scholes VE. Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ara-C Research Communications in Chemical Pathology and Pharmacology. 30: 365-368. PMID 7444164  0.88
1980 Hromas RA. Oral Roberts and objectivity Science. 208: 1212. DOI: 10.1126/Science.208.4449.1212-A  0.88
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