Lawrence J. Marnett - Publications

Affiliations: 
1975-1989 Wayne State University, Detroit, MI, United States 
 1989- Vanderbilt University School of Medicine, Nashville, TN, United States 
Area:
medicinal chemistry
Website:
https://medschool.vanderbilt.edu/biochemistry/person/lawrence-j-marnett/

234 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kingsley PJ, Rouzer CA, Morgan AJ, Patel S, Marnett LJ. Aspects of Prostaglandin Glycerol Ester Biology. Advances in Experimental Medicine and Biology. 1161: 77-88. PMID 31562623 DOI: 10.1007/978-3-030-21735-8_8  0.88
2019 Shockley EM, Rouzer CA, Marnett LJ, Deeds EJ, Lopez CF. Signal integration and information transfer in an allosterically regulated network. Npj Systems Biology and Applications. 5: 23. PMID 31341635 DOI: 10.1038/s41540-019-0100-9  0.44
2019 Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, et al. IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain. Science (New York, N.Y.). 365. PMID 31320508 DOI: 10.1126/science.aau6499  0.44
2019 Wepy JA, Galligan JJ, Kingsley PJ, Xu S, Goodman MC, Tallman KA, Rouzer CA, Marnett LJ. Erratum: Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling. Journal of Lipid Research. 60: 1345. PMID 31262966 DOI: 10.1194/jlr.ERR119000139  0.52
2019 Uddin MJ, Wilson AJ, Crews BC, Malerba P, Uddin MI, Kingsley PJ, Ghebreselasie K, Daniel CK, Nickels ML, Tantawy MN, Jashim E, Manning HC, Khabele D, Marnett LJ. Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer. Acs Omega. 4: 9251-9261. PMID 31172046 DOI: 10.1021/acsomega.9b01093  0.44
2019 Xu S, Uddin MJ, Banerjee S, Duggan K, Musee J, Kiefer JR, Ghebreselasie K, Rouzer CA, Marnett LJ. Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. The Journal of Biological Chemistry. PMID 31000626 DOI: 10.1074/jbc.RA119.007405  0.44
2018 Wepy JA, Galligan JJ, Kingsley PJ, Xu S, Goodman MC, Tallman KA, Rouzer CA, Marnett LJ. Lysophospholipases Cooperate to Mediate Lipid Homeostasis and Lysophospholipid Signaling. Journal of Lipid Research. PMID 30482805 DOI: 10.1194/jlr.M087890  0.52
2018 Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ. Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150385 DOI: 10.1073/pnas.1802901115  0.48
2018 Cavener VS, Gaulden A, Pennipede D, Jagasia P, Uddin J, Marnett LJ, Patel S. Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice. Frontiers in Neuroscience. 12: 479. PMID 30108473 DOI: 10.3389/fnins.2018.00479  0.88
2018 Morgan A, Kingsley PJ, Mitchener MM, Altemus M, Patrick T, Gaulden A, Marnett LJ, Patel S. Detection of cyclooxygenase-2-derived oxygenation products of the endogenous cannabinoid 2-arachidonoylglycerol in mouse brain. Acs Chemical Neuroscience. PMID 29722963 DOI: 10.1021/acschemneuro.7b00499  0.88
2018 Bedse G, Bluett RJ, Patrick TA, Romness NK, Gaulden AD, Kingsley PJ, Plath N, Marnett LJ, Patel S. Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors. Translational Psychiatry. 8: 92. PMID 29695817 DOI: 10.1038/s41398-018-0141-7  0.88
2018 Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ. Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA. Nucleic Acids Research. PMID 29438559 DOI: 10.1093/nar/gky089  0.48
2018 Goodman MC, Xu S, Rouzer CA, Banerjee S, Ghebreselasie K, Migliore M, Piomelli D, Marnett LJ. Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. The Journal of Biological Chemistry. PMID 29326169 DOI: 10.1074/jbc.M117.802058  0.44
2017 Beavers WN, Rose KL, Galligan JJ, Mitchener MM, Rouzer CA, Tallman KA, Lamberson CR, Wang X, Hill S, Ivanova PT, Brown HA, Zhang B, Porter NA, Marnett LJ. Protein Modification by Endogenously Generated Lipid Electrophiles: Mitochondria as the Source and Target. Acs Chemical Biology. PMID 28613820 DOI: 10.1021/acschembio.7b00480  0.52
2017 Bedse G, Hartley ND, Neale E, Gaulden AD, Patrick TA, Kingsley PJ, Uddin MJ, Plath N, Marnett LJ, Patel S. Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety. Biological Psychiatry. PMID 28438413 DOI: 10.1016/j.biopsych.2017.03.002  0.88
2017 Bluett RJ, Báldi R, Haymer A, Gaulden AD, Hartley ND, Parrish WP, Baechle J, Marcus DJ, Mardam-Bey R, Shonesy BC, Uddin MJ, Marnett LJ, Mackie K, Colbran RJ, Winder DG, et al. Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. Nature Communications. 8: 14782. PMID 28348378 DOI: 10.1038/ncomms14782  0.88
2017 Aldrovandi M, Hinz C, Lauder SN, Podmore H, Hornshaw M, Slatter DA, Tyrrell VJ, Clark SR, Marnett LJ, Collins PW, Murphy RC, O'Donnell VB. DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. Redox Biology. 11: 663-672. PMID 28160743 DOI: 10.1016/j.redox.2017.01.001  0.36
2016 Galligan JJ, Kingsley PJ, Wauchope O, Mitchener MM, Camarillo JM, Wepy JA, Harris PS, Fritz KS, Marnett LJ. Quantitative Analysis and Discovery of Lysine and Arginine Modifications (QuARKMod). Analytical Chemistry. PMID 27982582 DOI: 10.1021/acs.analchem.6b04105  0.44
2016 Uddin MJ, Moore CE, Crews BC, Daniel CK, Ghebreselasie K, McIntyre JO, Marnett LJ, Jayagopal A. Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization. Journal of Biomedical Optics. 21: 90503. PMID 27626899 DOI: 10.1117/1.JBO.21.9.090503  0.32
2016 Foster DJ, Wilson JM, Remke DH, Mahmood MS, Uddin MJ, Wess J, Patel S, Marnett LJ, Niswender CM, Jones CK, Xiang Z, Lindsley CW, Rook JM, Conn PJ. Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release. Neuron. PMID 27618677 DOI: 10.1016/j.neuron.2016.08.017  0.88
2016 Uddin MJ, Crews BC, Xu S, Ghebreselasie K, Daniel CK, Kingsley PJ, Banerjee S, Marnett LJ. Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors. Acs Chemical Biology. PMID 27588346 DOI: 10.1021/acschembio.6b00560  0.44
2016 Uddin MI, Evans SM, Craft JR, Capozzi ME, McCollum GW, Yang R, Marnett LJ, Uddin MJ, Jayagopal A, Penn JS. In Vivo Imaging of Retinal Hypoxia in a Model of Oxygen-Induced Retinopathy. Scientific Reports. 6: 31011. PMID 27491345 DOI: 10.1038/srep31011  0.32
2016 Adeniji AO, Uddin MJ, Zang T, Tamae D, Wangtrakuldee P, Marnett LJ, Penning TM. Discovery of (R)-2-(6-methoxynaphthalen-2-yl)butanoic acid As a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor. Journal of Medicinal Chemistry. PMID 27486833 DOI: 10.1021/acs.jmedchem.6b00160  0.32
2016 Kudalkar SN, Kingsley PJ, Marnett LJ. Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. Methods in Molecular Biology (Clifton, N.J.). 1412: 205-15. PMID 27245906 DOI: 10.1007/978-1-4939-3539-0_21  0.44
2016 Gamble-George JC, Baldi R, Halladay L, Kocharian A, Hartley N, Silva CG, Roberts H, Haymer A, Marnett LJ, Holmes A, Patel S. Cyclooxygenase-2 inhibition reduces stress-induced affective pathology. Elife. 5. PMID 27162170 DOI: 10.7554/eLife.14137  0.88
2016 Hinz C, Aldrovandi M, Uhlson C, Marnett LJ, Longhurst HJ, Warner TD, Alam S, Slatter DA, Lauder SN, Allen-Redpath K, Collins PW, Murphy RC, Thomas CP, O'Donnell VB. Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid. The Journal of Biological Chemistry. PMID 27129261 DOI: 10.1074/jbc.M115.700609  0.36
2016 Uddin MJ, Werfel TA, Crews BC, Gupta MK, Kavanaugh TE, Kingsley PJ, Boyd K, Marnett LJ, Duvall CL. Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer. Biomaterials. 92: 71-80. PMID 27043768 DOI: 10.1016/j.biomaterials.2016.03.028  0.88
2016 Cook PJ, Thomas R, Kingsley PJ, Shimizu F, Montrose DC, Marnett LJ, Tabar VS, Dannenberg AJ, Benezra R. Cox-2-derived PGE2 induces Id1-dependent radiation resistance and self-renewal in experimental glioblastoma. Neuro-Oncology. PMID 27022132 DOI: 10.1093/neuonc/now049  0.44
2016 Camarillo JM, Rose KL, Galligan JJ, Xu S, Marnett LJ. Covalent modification of CDK2 by 4-hydroxynonenal as a mechanism of inhibition of cell cycle progression. Chemical Research in Toxicology. PMID 26910110 DOI: 10.1021/acs.chemrestox.5b00485  0.88
2016 Kudalkar SN, Rouzer CA, Marnett LJ. Chapter 11: The peroxidase and cyclooxygenase activity of prostaglandin H synthase Rsc Metallobiology. 2016: 247-271. DOI: 10.1039/9781782622628-00245  0.88
2015 Konkle ME, Blobaum AL, Moth CW, Prusakiewicz JJ, Xu S, Ghebreselasie K, Akingbade D, Jacobs AT, Rouzer CA, Lybrand TP, Marnett LJ. A Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics. Biochemistry. PMID 26704937 DOI: 10.1021/acs.biochem.5b01222  0.88
2015 Wauchope OR, Beavers WN, Galligan JJ, Mitchener MM, Kingsley PJ, Marnett LJ. Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome. Chemical Research in Toxicology. PMID 26469224 DOI: 10.1021/acs.chemrestox.5b00340  0.88
2015 Wang JW, Woodward DF, Martos JL, Cornell CL, Carling RW, Kingsley PJ, Marnett LJ. Multitargeting of selected prostanoid receptors provides agents with enhanced anti-inflammatory activity in macrophages. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26420849 DOI: 10.1096/fj.15-275610  0.44
2015 Mitchener MM, Hermanson DJ, Shockley EM, Brown HA, Lindsley CW, Reese J, Rouzer CA, Lopez CF, Marnett LJ. Competition and allostery govern substrate selectivity of cyclooxygenase-2. Proceedings of the National Academy of Sciences of the United States of America. 112: 12366-71. PMID 26392530 DOI: 10.1073/pnas.1507307112  0.88
2015 Neumann W, Xu S, Sárosi MB, Scholz MS, Crews BC, Ghebreselasie K, Banerjee S, Marnett LJ, Hey-Hawkins HC. nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2. Chemmedchem. PMID 26088701 DOI: 10.1002/cmdc.201500199  0.88
2015 Wilson AJ, Fadare O, Beeghly-Fadiel A, Son DS, Liu Q, Zhao S, Saskowski J, Uddin MJ, Daniel C, Crews B, Lehmann BD, Pietenpol JA, Crispens MA, Marnett LJ, Khabele D. Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer. Oncotarget. PMID 25972361  0.32
2015 Uddin MJ, Crews BC, Ghebreselasie K, Daniel CK, Kingsley PJ, Xu S, Marnett LJ. Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe. Journal of Biomedical Optics. 20: 50502. PMID 25970082 DOI: 10.1117/1.JBO.20.5.050502  0.44
2015 Uddin MI, Evans SM, Craft JR, Marnett LJ, Uddin MJ, Jayagopal A. Applications of azo-based probes for imaging retinal hypoxia. Acs Medicinal Chemistry Letters. 6: 445-9. PMID 25893047 DOI: 10.1021/ml5005206  0.88
2015 Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, et al. Next-generation sequencing reveals the biological significance of the N2,3-ethenoguanine lesion in vivo. Nucleic Acids Research. 43: 5489-500. PMID 25837992 DOI: 10.1093/nar/gkv243  0.88
2015 Blobaum AL, Xu S, Rowlinson SW, Duggan KC, Banerjee S, Kudalkar SN, Birmingham WR, Ghebreselasie K, Marnett LJ. Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2. The Journal of Biological Chemistry. 290: 12793-803. PMID 25825493 DOI: 10.1074/jbc.M114.635987  0.88
2015 Ra H, González-González E, Uddin MJ, King BL, Lee A, Ali-Khan I, Marnett LJ, Tang JY, Contag CH. Detection of non-melanoma skin cancer by in vivo fluorescence imaging with fluorocoxib A. Neoplasia (New York, N.Y.). 17: 201-7. PMID 25748239 DOI: 10.1016/j.neo.2014.12.009  0.32
2015 Aluise CD, Camarillo JM, Shimozu Y, Galligan JJ, Rose KL, Tallman KA, Marnett LJ. Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal. Chemical Research in Toxicology. 28: 817-27. PMID 25739016 DOI: 10.1021/acs.chemrestox.5b00038  0.88
2015 Kudalkar SN, Nikas SP, Kingsley PJ, Xu S, Galligan JJ, Rouzer CA, Banerjee S, Ji L, Eno MR, Makriyannis A, Marnett LJ. 13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase. The Journal of Biological Chemistry. 290: 7897-909. PMID 25648895 DOI: 10.1074/jbc.M114.634014  0.88
2015 Wilson AJ, Fadare O, Beeghly-Fadiel A, Son DS, Liu Q, Zhao S, Saskowski J, Uddin MJ, Daniel C, Crews B, Lehmann BD, Pietenpol JA, Crispens MA, Marnett LJ, Khabele D. Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer Oncotarget. 6: 21353-21368.  0.32
2014 Xu S, Rouzer CA, Marnett LJ. Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyond. Iubmb Life. 66: 803-11. PMID 25537198 DOI: 10.1002/iub.1334  0.88
2014 Shonesy BC, Bluett RJ, Ramikie TS, Báldi R, Hermanson DJ, Kingsley PJ, Marnett LJ, Winder DG, Colbran RJ, Patel S. Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation. Cell Reports. 9: 1644-53. PMID 25466252 DOI: 10.1016/j.celrep.2014.11.001  0.88
2014 Uddin MJ, Elleman AV, Ghebreselasie K, Daniel CK, Crews BC, Nance KD, Huda T, Marnett LJ. Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors. Acs Medicinal Chemistry Letters. 5: 1254-8. PMID 25408841 DOI: 10.1021/ml500344j  0.88
2014 Manna JD, Wepy JA, Hsu KL, Chang JW, Cravatt BF, Marnett LJ. Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. The Journal of Biological Chemistry. 289: 33741-53. PMID 25301951 DOI: 10.1074/jbc.M114.582353  0.88
2014 Shuck SC, Wauchope OR, Rose KL, Kingsley PJ, Rouzer CA, Shell SM, Sugitani N, Chazin WJ, Zagol-Ikapitte I, Boutaud O, Oates JA, Galligan JJ, Beavers WN, Marnett LJ. Protein modification by adenine propenal. Chemical Research in Toxicology. 27: 1732-42. PMID 25211669 DOI: 10.1021/tx500218g  0.88
2014 Singh V, Fedeles BI, Li D, Delaney JC, Kozekov ID, Kozekova A, Marnett LJ, Rizzo CJ, Essigmann JM. Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB. Chemical Research in Toxicology. 27: 1619-31. PMID 25157679 DOI: 10.1021/tx5002817  0.88
2014 Galligan JJ, Rose KL, Beavers WN, Hill S, Tallman KA, Tansey WP, Marnett LJ. Stable histone adduction by 4-oxo-2-nonenal: a potential link between oxidative stress and epigenetics. Journal of the American Chemical Society. 136: 11864-6. PMID 25099620 DOI: 10.1021/ja503604t  0.88
2014 Derewacz DK, McNees CR, Scalmani G, Covington CL, Shanmugam G, Marnett LJ, Polavarapu PL, Bachmann BO. Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete. Journal of Natural Products. PMID 25046128 DOI: 10.1021/np400742p  0.88
2014 Beavers WN, Serwa R, Shimozu Y, Tallman KA, Vaught M, Dalvie ED, Marnett LJ, Porter NA. ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: free radical and enzymatic oxidations. Journal of the American Chemical Society. 136: 11529-39. PMID 25034362 DOI: 10.1021/ja506038v  0.88
2014 Bluett RJ, Gamble-George JC, Hermanson DJ, Hartley ND, Marnett LJ, Patel S. Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. Translational Psychiatry. 4: e408. PMID 25004388 DOI: 10.1038/tp.2014.53  0.88
2014 Uddin MJ, Crews BC, Huda I, Ghebreselasie K, Daniel CK, Marnett LJ. Trifluoromethyl fluorocoxib a detects cyclooxygenase-2 expression in inflammatory tissues and human tumor xenografts. Acs Medicinal Chemistry Letters. 5: 446-50. PMID 24900856 DOI: 10.1021/ml400485g  0.88
2014 Rietjens IM, Cohen SM, Fukushima S, Gooderham NJ, Hecht S, Marnett LJ, Smith RL, Adams TB, Bastaki M, Harman CG, Taylor SV. Impact of structural and metabolic variations on the toxicity and carcinogenicity of hydroxy- and alkoxy-substituted allyl- and propenylbenzenes. Chemical Research in Toxicology. 27: 1092-103. PMID 24857813 DOI: 10.1021/tx500109s  0.88
2014 Hermanson DJ, Gamble-George JC, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation. Trends in Pharmacological Sciences. 35: 358-67. PMID 24845457 DOI: 10.1016/j.tips.2014.04.006  0.88
2014 Perrone MG, Malerba P, Uddin MJ, Vitale P, Panella A, Crews BC, Daniel CK, Ghebreselasie K, Nickels M, Tantawy MN, Manning HC, Marnett LJ, Scilimati A. PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation. European Journal of Medicinal Chemistry. 80: 562-8. PMID 24832612 DOI: 10.1016/j.ejmech.2014.04.074  0.88
2014 Neumann W, Crews BC, Marnett LJ, Hey-Hawkins E. Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance. Chemmedchem. 9: 1150-3. PMID 24801194 DOI: 10.1002/cmdc.201402074  0.88
2014 Marnett LJ, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Rietjens IM, Smith RL, Adams TB, Bastaki M, Harman CL, McGowen MM, Taylor SV. GRASr2 evaluation of aliphatic acyclic and alicyclic terpenoid tertiary alcohols and structurally related substances used as flavoring ingredients. Journal of Food Science. 79: R428-41. PMID 24689743 DOI: 10.1111/1750-3841.12407  0.88
2014 Codreanu SG, Ullery JC, Zhu J, Tallman KA, Beavers WN, Porter NA, Marnett LJ, Zhang B, Liebler DC. Alkylation damage by lipid electrophiles targets functional protein systems. Molecular & Cellular Proteomics : McP. 13: 849-59. PMID 24429493 DOI: 10.1074/mcp.M113.032953  0.88
2014 Xu S, Hermanson DJ, Banerjee S, Ghebreselasie K, Clayton GM, Garavito RM, Marnett LJ. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. The Journal of Biological Chemistry. 289: 6799-808. PMID 24425867 DOI: 10.1074/jbc.M113.517987  0.88
2014 Shuck SC, Rose KL, Marnett LJ. Mass spectrometric methods for the analysis of nucleoside-protein cross-links: application to oxopropenyl-deoxyadenosine. Chemical Research in Toxicology. 27: 136-46. PMID 24359270 DOI: 10.1021/tx400384e  0.88
2014 Rogalla S, Sensarn S, King BL, Schmidt TL, Ra H, Garai E, Rimm D, Ostrov D, Uddin MJ, Marnett LJ, Zavaleta C, Gambhir SS, Crawford JM, Van Dam J, Friedland S, et al. Using optics to reduce the time and distance between the patient and the diagnostic event Translational Research in Biophotonics: Four National Cancer Institute Case Studies. 243-284. DOI: 10.1117/3.1002515.ch8  0.32
2014 Marnett LJ, Kingsley PJ, Hermanson DJ. Oxidative Metabolites of Endocannabinoids Formed by Cyclooxygenase-2 The Endocannabinoidome: the World of Endocannabinoids and Related Mediators. 49-65. DOI: 10.1016/B978-0-12-420126-2.00004-3  0.88
2013 Maddukuri L, Shuck SC, Eoff RL, Zhao L, Rizzo CJ, Guengerich FP, Marnett LJ. Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine. Biochemistry. 52: 8766-76. PMID 24171480 DOI: 10.1021/bi401103k  0.88
2013 Windsor MA, Valk PL, Xu S, Banerjee S, Marnett LJ. Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Bioorganic & Medicinal Chemistry Letters. 23: 5860-4. PMID 24060487 DOI: 10.1016/j.bmcl.2013.08.097  0.88
2013 Liu Q, Ullery J, Zhu J, Liebler DC, Marnett LJ, Zhang B. RNA-seq data analysis at the gene and CDS levels provides a comprehensive view of transcriptome responses induced by 4-hydroxynonenal. Molecular Biosystems. 9: 3036-46. PMID 24056865 DOI: 10.1039/c3mb70114j  0.88
2013 Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. Nature Neuroscience. 16: 1291-8. PMID 23912944 DOI: 10.1038/nn.3480  0.88
2013 Aldrovandi M, Hammond VJ, Podmore H, Hornshaw M, Clark SR, Marnett LJ, Slatter DA, Murphy RC, Collins PW, O'Donnell VB. Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation. Journal of Lipid Research. 54: 3085-97. PMID 23883581 DOI: 10.1194/jlr.M041533  0.88
2013 Soares CO, Boiani M, Marnett LJ, Bechara EJ. Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance. Free Radical Research. 47: 672-82. PMID 23758064 DOI: 10.3109/10715762.2013.814126  0.88
2013 Blobaum AL, Uddin MJ, Felts AS, Crews BC, Rouzer CA, Marnett LJ. The 2'-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor. Acs Medicinal Chemistry Letters. 4: 486-490. PMID 23687559 DOI: 10.1021/ml400066a  0.88
2013 Mohebati A, Milne GL, Zhou XK, Duffield-Lillico AJ, Boyle JO, Knutson A, Bosworth BP, Kingsley PJ, Marnett LJ, Brown PH, Akpa EG, Szabo E, Dannenberg AJ. Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers. Cancer Prevention Research (Philadelphia, Pa.). 6: 646-55. PMID 23682075 DOI: 10.1158/1940-6207.CAPR-13-0083  0.88
2013 Cekanova M, Uddin MJ, Bartges JW, Callens A, Legendre AM, Rathore K, Wright L, Carter A, Marnett LJ. Molecular imaging of cyclooxygenase-2 in canine transitional cell carcinomas in vitro and in vivo. Cancer Prevention Research (Philadelphia, Pa.). 6: 466-76. PMID 23531445 DOI: 10.1158/1940-6207.CAPR-12-0358  0.88
2013 Uddin MJ, Crews BC, Ghebreselasie K, Marnett LJ. Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents. Bioconjugate Chemistry. 24: 712-23. PMID 23488616 DOI: 10.1021/bc300693w  0.88
2013 Connor RE, Codreanu SG, Marnett LJ, Liebler DC. Targeted protein capture for analysis of electrophile-protein adducts. Methods in Molecular Biology (Clifton, N.J.). 987: 163-76. PMID 23475677 DOI: 10.1007/978-1-62703-321-3_15  0.88
2013 Liedtke AJ, Adeniji AO, Chen M, Byrns MC, Jin Y, Christianson DW, Marnett LJ, Penning TM. Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17β-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer. Journal of Medicinal Chemistry. 56: 2429-46. PMID 23432095 DOI: 10.1021/jm3017656  0.88
2013 Boiani M, Daniel C, Liu X, Hogarty MD, Marnett LJ. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737. The Journal of Biological Chemistry. 288: 6980-90. PMID 23341456 DOI: 10.1074/jbc.M112.414177  0.88
2013 Tallman KA, Armstrong MD, Milne SB, Marnett LJ, Brown HA, Porter NA. Cobalt carbonyl complexes as probes for alkyne-tagged lipids. Journal of Lipid Research. 54: 859-68. PMID 23307946 DOI: 10.1194/jlr.D033332  0.88
2013 Sevick-Muraca EM, Akers WJ, Joshi BP, Luker GD, Cutler CS, Marnett LJ, Contag CH, Wang TD, Azhdarinia A. Advancing the translation of optical imaging agents for clinical imaging. Biomedical Optics Express. 4: 160-70. PMID 23304655 DOI: 10.1364/BOE.4.000160  0.88
2013 Laube M, Neumann W, Scholz M, Lönnecke P, Crews B, Marnett LJ, Pietzsch J, Kniess T, Hey-Hawkins E. 2-Carbaborane-3-phenyl-1H-indoles--synthesis via McMurry reaction and cyclooxygenase (COX) inhibition activity. Chemmedchem. 8: 329-35. PMID 23303738 DOI: 10.1002/cmdc.201200455  0.88
2013 Aluise CD, Rose K, Boiani M, Reyzer ML, Manna JD, Tallman K, Porter NA, Marnett LJ. Peptidyl-prolyl cis/trans-isomerase A1 (Pin1) is a target for modification by lipid electrophiles. Chemical Research in Toxicology. 26: 270-9. PMID 23231502 DOI: 10.1021/tx300449g  0.88
2013 Yang Y, Yang H, Wang Z, Varadaraj K, Kumari SS, Mergler S, Okada Y, Saika S, Kingsley PJ, Marnett LJ, Reinach PS. Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury. Cellular Signalling. 25: 501-11. PMID 23142606 DOI: 10.1016/j.cellsig.2012.10.015  0.88
2013 Marnett LJ, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Rietjens IMCM, Smith RL, Adams TB, Hallagan JB, Harman C, McGowen MM, Taylor SV. Gras: Flavoring substances 26 Food Technology. 67: 38-43.  0.88
2013 Bornhop DJ, Kussrow A, Olmsted I, Baksh M, Finn MG, Marnett L, Windsor M, Pesciotta EN, Flowers RA, Massion P, Hassanein M. Using back-scattering interferometry to aid in probe development and drug efficacy monitoring Optical Molecular Probes, Imaging and Drug Delivery, Omp 2013. MM4C.6.  0.88
2012 Nolting DD, Nickels M, Tantawy MN, Yu JY, Xie J, Peterson TE, Crews BC, Marnett L, Gore JC, Pham W. Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging. Frontiers in Oncology. 2: 207. PMID 23316477 DOI: 10.3389/fonc.2012.00207  0.88
2012 Liedtke AJ, Kim K, Stec DF, Sulikowski GA, Marnett LJ. Straightforward protocol for the efficient synthesis of varied N(1)-acylated (aza)indole 2-/3-alkanoic acids and esters: optimization and scale-up. Tetrahedron. 68: 10049-10058. PMID 23204595 DOI: 10.1016/j.tet.2012.08.044  0.88
2012 Cekanova M, Uddin MJ, Legendre AM, Galyon G, Bartges JW, Callens A, Martin-Jimenez T, Marnett LJ. Single-dose safety and pharmacokinetic evaluation of fluorocoxib A: pilot study of novel cyclooxygenase-2-targeted optical imaging agent in a canine model. Journal of Biomedical Optics. 17: 116002. PMID 23117797 DOI: 10.1117/1.JBO.17.11.116002  0.88
2012 Windsor MA, Hermanson DJ, Kingsley PJ, Xu S, Crews BC, Ho W, Keenan CM, Banerjee S, Sharkey KA, Marnett LJ. Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes. Acs Medicinal Chemistry Letters. 3: 759-763. PMID 22984634 DOI: 10.1021/ml3001616  0.88
2012 Kotapati S, Maddukuri L, Wickramaratne S, Seneviratne U, Goggin M, Pence MG, Villalta P, Guengerich FP, Marnett L, Tretyakova N. Translesion synthesis across 1,N6-(2-hydroxy-3-hydroxymethylpropan-1,3-diyl)-2'-deoxyadenosine (1,N6-γ-HMHP-dA) adducts by human and archebacterial DNA polymerases. The Journal of Biological Chemistry. 287: 38800-11. PMID 22977231 DOI: 10.1074/jbc.M112.396788  0.88
2012 Musee J, Marnett LJ. Prostaglandin H synthase-2-catalyzed oxygenation of 2-arachidonoylglycerol is more sensitive to peroxide tone than oxygenation of arachidonic acid. The Journal of Biological Chemistry. 287: 37383-94. PMID 22942274 DOI: 10.1074/jbc.M112.381202  0.88
2012 Xu S, Mueser TC, Marnett LJ, Funk MO. Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis. Structure (London, England : 1993). 20: 1490-7. PMID 22795085 DOI: 10.1016/j.str.2012.06.003  0.88
2012 Scholz M, Blobaum AL, Marnett LJ, Hey-Hawkins E. Ortho-carbaborane derivatives of indomethacin as cyclooxygenase (COX)-2 selective inhibitors. Bioorganic & Medicinal Chemistry. 20: 4830-7. PMID 22748709 DOI: 10.1016/j.bmc.2012.05.063  0.88
2012 Gregori-Puigjané E, Setola V, Hert J, Crews BA, Irwin JJ, Lounkine E, Marnett L, Roth BL, Shoichet BK. Identifying mechanism-of-action targets for drugs and probes. Proceedings of the National Academy of Sciences of the United States of America. 109: 11178-83. PMID 22711801 DOI: 10.1073/pnas.1204524109  0.88
2012 Eisenbrand G, Gates KS, Hecht SS, Janzowski C, Keefer LK, Marnett LJ, Tannenbaum SR. Richard Loeppky (1937-2012). Chemical Research in Toxicology. 25: 1155-6. PMID 22632260 DOI: 10.1021/tx300219b  0.88
2012 Aldrich MB, Marshall MV, Sevick-Muraca EM, Lanza G, Kotyk J, Culver J, Wang LV, Uddin J, Crews BC, Marnett LJ, Liao JC, Contag C, Crawford JM, Wang K, Reisdorph B, et al. Seeing it through: translational validation of new medical imaging modalities. Biomedical Optics Express. 3: 764-76. PMID 22574264 DOI: 10.1364/BOE.3.000764  0.88
2012 Ullery JC, Marnett LJ. Protein modification by oxidized phospholipids and hydrolytically released lipid electrophiles: Investigating cellular responses. Biochimica Et Biophysica Acta. 1818: 2424-35. PMID 22562025 DOI: 10.1016/j.bbamem.2012.04.014  0.88
2012 Marnett LJ. Inflammation and cancer: chemical approaches to mechanisms, imaging, and treatment. The Journal of Organic Chemistry. 77: 5224-38. PMID 22515568 DOI: 10.1021/jo300214d  0.88
2012 Liedtke AJ, Crews BC, Daniel CM, Blobaum AL, Kingsley PJ, Ghebreselasie K, Marnett LJ. Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. Journal of Medicinal Chemistry. 55: 2287-300. PMID 22263894 DOI: 10.1021/jm201528b  0.88
2012 Marnett LJ. On a high note. Chemical Research in Toxicology. 25: 1. PMID 22242943 DOI: 10.1021/tx200522h  0.88
2012 Akingbade D, Kingsley PJ, Shuck SC, Cooper T, Carnahan R, Szekely J, Marnett LJ. Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo. Chemical Research in Toxicology. 25: 454-61. PMID 22211372 DOI: 10.1021/tx200494h  0.88
2012 Marnett LJ. Goodbye columbus: Reflections on twenty-five years of editing CRT Chemical Research in Toxicology. 25: 2619-2622. DOI: 10.1021/tx300433u  0.88
2011 Brogan JT, Stoops SL, Crews BC, Marnett LJ, Lindsley CW. Total Synthesis (+)-7-Bromotrypargine and Unnatural Analogs: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic Relevance. Acs Chemical Neuroscience. 2: 633-639. PMID 22247792 DOI: 10.1021/cn200075n  0.88
2011 Ni TT, Rellinger EJ, Mukherjee A, Xie S, Stephens L, Thorne CA, Kim K, Hu J, Lee E, Marnett L, Hatzopoulos AK, Zhong TP. Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling. Chemistry & Biology. 18: 1658-68. PMID 22195568 DOI: 10.1016/j.chembiol.2011.09.015  0.88
2011 Duggan KC, Hermanson DJ, Musee J, Prusakiewicz JJ, Scheib JL, Carter BD, Banerjee S, Oates JA, Marnett LJ. (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. Nature Chemical Biology. 7: 803-9. PMID 22053353 DOI: 10.1038/nchembio.663  0.88
2011 Hermanson DJ, Marnett LJ. Cannabinoids, endocannabinoids, and cancer. Cancer Metastasis Reviews. 30: 599-612. PMID 22038019 DOI: 10.1007/s10555-011-9318-8  0.88
2011 Brown HA, Marnett LJ. Introduction to lipid biochemistry, metabolism, and signaling. Chemical Reviews. 111: 5817-20. PMID 21951202 DOI: 10.1021/cr200363s  0.88
2011 Rouzer CA, Marnett LJ. Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways. Chemical Reviews. 111: 5899-921. PMID 21923193 DOI: 10.1021/cr2002799  0.88
2011 Uddin MJ, Crews BC, Ghebreselasie K, Huda I, Kingsley PJ, Ansari MS, Tantawy MN, Reese J, Marnett LJ. Fluorinated COX-2 inhibitors as agents in PET imaging of inflammation and cancer. Cancer Prevention Research (Philadelphia, Pa.). 4: 1536-45. PMID 21900596 DOI: 10.1158/1940-6207.CAPR-11-0120  0.88
2011 Rouzer CA, Marnett LJ. Green tea gets molecular. Cancer Prevention Research (Philadelphia, Pa.). 4: 1343-5. PMID 21893494 DOI: 10.1158/1940-6207.CAPR-11-0372  0.88
2011 Manna JD, Reyzer ML, Latham JC, Weaver CD, Marnett LJ, Caprioli RM. High-throughput quantification of bioactive lipids by MALDI mass spectrometry: application to prostaglandins. Analytical Chemistry. 83: 6683-8. PMID 21770391 DOI: 10.1021/ac201224n  0.88
2011 Connor RE, Marnett LJ, Liebler DC. Protein-selective capture to analyze electrophile adduction of hsp90 by 4-hydroxynonenal. Chemical Research in Toxicology. 24: 1275-82. PMID 21749116 DOI: 10.1021/tx200157t  0.88
2011 Adams TB, Gavin CL, McGowen MM, Waddell WJ, Cohen SM, Feron VJ, Marnett LJ, Munro IC, Portoghese PS, Rietjens IM, Smith RL. The FEMA GRAS assessment of aliphatic and aromatic terpene hydrocarbons used as flavor ingredients. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 49: 2471-94. PMID 21726592 DOI: 10.1016/j.fct.2011.06.011  0.88
2011 Zhang B, Shi Z, Duncan DT, Prodduturi N, Marnett LJ, Liebler DC. Relating protein adduction to gene expression changes: a systems approach. Molecular Biosystems. 7: 2118-27. PMID 21594272 DOI: 10.1039/c1mb05014a  0.88
2011 Scholz M, Blobaum AL, Marnett LJ, Hey-Hawkins E. Synthesis and evaluation of carbaborane derivatives of indomethacin as cyclooxygenase inhibitors. Bioorganic & Medicinal Chemistry. 19: 3242-8. PMID 21524587 DOI: 10.1016/j.bmc.2011.03.054  0.88
2011 Marnett L. Systems toxicology, just accepted service, and earthquakes Chemical Research in Toxicology. 24: 429. PMID 21500783 DOI: 10.1021/tx200118z  0.88
2011 Uddin MJ, Crews BC, Ghebreselasie K, Tantawy MN, Marnett LJ. [I]-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation. Acs Medicinal Chemistry Letters. 2: 160-164. PMID 21318094 DOI: 10.1021/ml100232q  0.88
2011 McGrath CE, Tallman KA, Porter NA, Marnett LJ. Structure-activity analysis of diffusible lipid electrophiles associated with phospholipid peroxidation: 4-hydroxynonenal and 4-oxononenal analogues. Chemical Research in Toxicology. 24: 357-70. PMID 21291287 DOI: 10.1021/tx100323m  0.88
2011 Trostchansky A, Bonilla L, Thomas CP, O'Donnell VB, Marnett LJ, Radi R, Rubbo H. Nitroarachidonic acid, a novel peroxidase inhibitor of prostaglandin endoperoxide H synthases 1 and 2. The Journal of Biological Chemistry. 286: 12891-900. PMID 21266582 DOI: 10.1074/jbc.M110.154518  0.88
2011 Wang X, Kingsley PJ, Marnett LJ, Eling TE. The role of NAG-1/GDF15 in the inhibition of intestinal polyps in APC/Min mice by sulindac. Cancer Prevention Research (Philadelphia, Pa.). 4: 150-60. PMID 21205743 DOI: 10.1158/1940-6207.CAPR-10-0196  0.88
2011 Smith RL, Waddell WJ, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Marnett LJ, Portoghese PS, Rietjens IMCM, Adams TB, Gavin CL, Mcgowen MM, Taylor SV. GRAS flavoring substances 25 Food Technology. 65: 44-75.  0.88
2010 Uddin MJ, Schulte MI, Maddukuri L, Harp J, Marnett LJ. Semisynthesis of 6-chloropurine-2'-deoxyriboside 5'-dimethoxytrityl 3'-(2-cyanoethyl-N,N-diisopropylamino)phosphoramidite and its use in the synthesis of fluorescently labeled oligonucleotides. Nucleosides, Nucleotides & Nucleic Acids. 29: 831-40. PMID 21128170 DOI: 10.1080/15257770.2010.530332  0.88
2010 Eoff RL, McGrath CE, Maddukuri L, Salamanca-Pinzón SG, Marquez VE, Marnett LJ, Guengerich FP, Egli M. Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues. Angewandte Chemie (International Ed. in English). 49: 7481-5. PMID 20814997 DOI: 10.1002/anie.201003168  0.88
2010 Duggan KC, Walters MJ, Musee J, Harp JM, Kiefer JR, Oates JA, Marnett LJ. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. The Journal of Biological Chemistry. 285: 34950-9. PMID 20810665 DOI: 10.1074/jbc.M110.162982  0.88
2010 Maddukuri L, Eoff RL, Choi JY, Rizzo CJ, Guengerich FP, Marnett LJ. In vitro bypass of the major malondialdehyde- and base propenal-derived DNA adduct by human Y-family DNA polymerases κ, ι, and Rev1. Biochemistry. 49: 8415-24. PMID 20726503 DOI: 10.1021/bi1009024  0.88
2010 Cline SD, Lodeiro MF, Marnett LJ, Cameron CE, Arnold JJ. Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M1dG. Nucleic Acids Research. 38: 7546-57. PMID 20671026 DOI: 10.1093/nar/gkq656  0.88
2010 Aldrich LN, Stoops SL, Crews BC, Marnett LJ, Lindsley CW. Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs. Bioorganic & Medicinal Chemistry Letters. 20: 5207-11. PMID 20655217 DOI: 10.1016/j.bmcl.2010.06.154  0.88
2010 Duggan KC, Musee J, Marnett LJ. Peroxidase active site activity assay. Methods in Molecular Biology (Clifton, N.J.). 644: 55-65. PMID 20645165 DOI: 10.1007/978-1-59745-364-6_6  0.88
2010 Bachmann BO, McNees R, Melancon BJ, Ghidu VP, Clark R, Crews BC, Deguire SM, Marnett LJ, Sulikowski GA. Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry. Organic Letters. 12: 2944-7. PMID 20515014 DOI: 10.1021/ol1009398  0.88
2010 Uddin MJ, Crews BC, Blobaum AL, Kingsley PJ, Gorden DL, McIntyre JO, Matrisian LM, Subbaramaiah K, Dannenberg AJ, Piston DW, Marnett LJ. Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents. Cancer Research. 70: 3618-27. PMID 20430759 DOI: 10.1158/0008-5472.CAN-09-2664  0.88
2010 Jacobs AT, Marnett LJ. Systems analysis of protein modification and cellular responses induced by electrophile stress. Accounts of Chemical Research. 43: 673-83. PMID 20218676 DOI: 10.1021/ar900286y  0.88
2010 Richie-Jannetta R, Nirodi CS, Crews BC, Woodward DF, Wang JW, Duff PT, Marnett LJ. Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins & Other Lipid Mediators. 92: 19-24. PMID 20152925 DOI: 10.1016/j.prostaglandins.2010.01.003  0.88
2010 Uddin MJ, Smithson DC, Brown KM, Crews BC, Connelly M, Zhu F, Marnett LJ, Guy RK. Podophyllotoxin analogues active versus Trypanosoma brucei. Bioorganic & Medicinal Chemistry Letters. 20: 1787-91. PMID 20129783 DOI: 10.1016/j.bmcl.2010.01.009  0.88
2010 Milne SB, Tallman KA, Serwa R, Rouzer CA, Armstrong MD, Marnett LJ, Lukehart CM, Porter NA, Brown HA. Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry. Nature Chemical Biology. 6: 205-207. PMID 20098428 DOI: 10.1038/nchembio.311  0.88
2010 Marnett LJ. A new decade Chemical Research in Toxicology. 23: 1. DOI: 10.1021/tx9004314  0.88
2010 Knutson CG, Marnett LJ. DNA Damage Caused by Endogenously Generated Products of Oxidative Stress The Chemical Biology of Dna Damage. 105-130. DOI: 10.1002/9783527630110.ch5  0.88
2010 Blobaum AL, Marnett LJ. NSAID Action and the Foundations for Cardiovascular Toxicity Cardiotoxicity of Non-Cardiovascular Drugs. 257-285. DOI: 10.1002/9780470660379.ch8  0.88
2010 Turman MV, Marnett LJ. Prostaglandin endoperoxide synthases: Structure, function, and synthesis of novel lipid signaling molecules Comprehensive Natural Products Ii: Chemistry and Biology. 1: 35-63.  0.88
2009 Tallman KA, Vila A, Porter NA, Marnett LJ. Measuring electrophile stress. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit17.11. PMID 23045010 DOI: 10.1002/0471140856.tx1711s40  0.88
2009 Turman MV, Kingsley PJ, Marnett LJ. Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inactivator of prostaglandin endoperoxide synthase. Biochemistry. 48: 12233-41. PMID 19928795 DOI: 10.1021/bi901181z  0.88
2009 Daniels RN, Melancon BJ, Wang EA, Crews BC, Marnett LJ, Sulikowski GA, Lindsley CW. Progress toward the total synthesis of lucentamycin A: total synthesis and biological evaluation of 8-epi-lucentamycin A. The Journal of Organic Chemistry. 74: 8852-5. PMID 19908916 DOI: 10.1021/jo902115s  0.88
2009 Patel S, Kingsley PJ, Mackie K, Marnett LJ, Winder DG. Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2699-709. PMID 19675536 DOI: 10.1038/npp.2009.101  0.88
2009 Prusakiewicz JJ, Duggan KC, Rouzer CA, Marnett LJ. Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid. Biochemistry. 48: 7353-5. PMID 19603831 DOI: 10.1021/bi900999z  0.88
2009 Ghidu VP, Ntai I, Wang J, Jacobs AT, Marnett LJ, Bachmann BO, Sulikowski GA. Combined chemical and biosynthetic route to access a new apoptolidin congener. Organic Letters. 11: 3032-4. PMID 19552384 DOI: 10.1021/ol901045v  0.88
2009 Kingsley PJ, Marnett LJ. Analysis of endocannabinoids, their congeners and COX-2 metabolites. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 2746-54. PMID 19505857 DOI: 10.1016/j.jchromb.2009.05.024  0.88
2009 Eoff RL, Stafford JB, Szekely J, Rizzo CJ, Egli M, Guengerich FP, Marnett LJ. Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Biochemistry. 48: 7079-88. PMID 19492857 DOI: 10.1021/bi9003588  0.88
2009 Walters MJ, Blobaum AL, Kingsley PJ, Felts AS, Sulikowski GA, Marnett LJ. The influence of double bond geometry in the inhibition of cyclooxygenases by sulindac derivatives. Bioorganic & Medicinal Chemistry Letters. 19: 3271-4. PMID 19427206 DOI: 10.1016/j.bmcl.2009.04.078  0.88
2009 Konkle ME, Hargrove TY, Kleshchenko YY, von Kries JP, Ridenour W, Uddin MJ, Caprioli RM, Marnett LJ, Nes WD, Villalta F, Waterman MR, Lepesheva GI. Indomethacin amides as a novel molecular scaffold for targeting Trypanosoma cruzi sterol 14alpha-demethylase. Journal of Medicinal Chemistry. 52: 2846-53. PMID 19354253 DOI: 10.1021/jm801643b  0.88
2009 Marnett LJ. Mechanisms of cyclooxygenase-2 inhibition and cardiovascular side effects: the plot thickens. Cancer Prevention Research (Philadelphia, Pa.). 2: 288-90. PMID 19336721 DOI: 10.1158/1940-6207.CAPR-09-0033  0.88
2009 Jacobs AT, Marnett LJ. HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins. The Journal of Biological Chemistry. 284: 9176-83. PMID 19179333 DOI: 10.1074/jbc.M808656200  0.88
2009 Knutson CG, Rubinson EH, Akingbade D, Anderson CS, Stec DF, Petrova KV, Kozekov ID, Guengerich FP, Rizzo CJ, Marnett LJ. Oxidation and glycolytic cleavage of etheno and propano DNA base adducts. Biochemistry. 48: 800-9. PMID 19132922 DOI: 10.1021/bi801654j  0.88
2009 Stafford JB, Eoff RL, Kozekova A, Rizzo CJ, Guengerich FP, Marnett LJ. Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one. Biochemistry. 48: 471-80. PMID 19108641 DOI: 10.1021/bi801591a  0.88
2009 Marnett LJ. Decoding endocannabinoid signaling. Nature Chemical Biology. 5: 8-9. PMID 19088712 DOI: 10.1038/nchembio0109-8  0.88
2009 Sun X, Wang H, Okabe M, Mackie K, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK. Genetic loss of Faah compromises male fertility in mice. Biology of Reproduction. 80: 235-42. PMID 18987328 DOI: 10.1095/biolreprod.108.072736  0.88
2009 Rouzer CA, Marnett LJ. Cyclooxygenases: structural and functional insights. Journal of Lipid Research. 50: S29-34. PMID 18952571 DOI: 10.1194/jlr.R800042-JLR200  0.88
2009 Marnett LJ. The COXIB experience: a look in the rearview mirror. Annual Review of Pharmacology and Toxicology. 49: 265-90. PMID 18851701 DOI: 10.1146/annurev.pharmtox.011008.145638  0.88
2009 Marnett LJ. Nanotoxicology - A new frontier Chemical Research in Toxicology. 22: 1491. DOI: 10.1021/tx900261y  0.88
2009 Marnett LJ. Chemical research in toxicology-from strength to strength Chemical Research in Toxicology. 22: 1-2. DOI: 10.1021/tx800470m  0.88
2009 Adams TB, Lucas Gavin C, Taylor SV, Waddell WJ, Cohen SM, Feron VJ, Goodman J, Rietjens IMCM, Marnett LJ, Portoghese PS, Smith RL. Corrigendum to: ''The FEMA GRAS assessment of a,b-unsaturated aldehydes and related substances used as flavor ingredients" [Food and Chemical Toxicology 46 (2008) 2935-2967] (DOI:10.1016/j.fct.2008.06.082) Food and Chemical Toxicology. 47: 2686. DOI: 10.1016/j.fct.2009.07.027  0.88
2009 Uddin MJ, Crews BC, Blobaum AL, Kingsley PJ, Ghebreselasie K, Saleh SS, Clanton JA, Baldwin RM, Marnett LJ. Synthesis and evaluation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents Journal of Labelled Compounds and Radiopharmaceuticals. 52: 387-393. DOI: 10.1002/jlcr.1615  0.88
2009 Smith RL, Waddell WJ, Cohen SM, Feron VJ, Marnett LJ, Portoghese PS, Rietjens IMCM, Adams TB, Gavin CL, Mcgowen MM, Taylor SV, Williams MC. Gras flavoring substances 24 Food Technology. 63: 46-62.  0.88
2008 Uddin MJ, Marnett LJ. Synthesis of 5- and 6-carboxy-X-rhodamines. Organic Letters. 10: 4799-801. PMID 18837556 DOI: 10.1021/ol801904k  0.88
2008 Toscano CD, Kingsley PJ, Marnett LJ, Bosetti F. NMDA-induced seizure intensity is enhanced in COX-2 deficient mice Neurotoxicology. 29: 1114-1120. PMID 18834901 DOI: 10.1016/j.neuro.2008.08.008  0.88
2008 Marnett LJ. Biochemistry: Divergence from the superfamily Nature. 455: 300-301. PMID 18800126 DOI: 10.1038/455300a  0.88
2008 VanderVeen LA, Harris TM, Jen-Jacobson L, Marnett LJ. Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI. Chemical Research in Toxicology. 21: 1733-8. PMID 18690724 DOI: 10.1021/tx800092g  0.88
2008 Felts AS, Siegel BS, Young SM, Moth CW, Lybrand TP, Dannenberg AJ, Marnett LJ, Subbaramaiah K. Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition. Journal of Medicinal Chemistry. 51: 4911-9. PMID 18665581 DOI: 10.1021/jm700969c  0.88
2008 Adams TB, Gavin CL, Taylor SV, Waddell WJ, Cohen SM, Feron VJ, Goodman J, Rietjens IM, Marnett LJ, Portoghese PS, Smith RL. The FEMA GRAS assessment of alpha,beta-unsaturated aldehydes and related substances used as flavor ingredients. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 2935-67. PMID 18644420 DOI: 10.1016/j.fct.2008.06.082  0.88
2008 Wang Y, Musser SK, Saleh S, Marnett LJ, Egli M, Stone MP. Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV. Biochemistry. 47: 7322-34. PMID 18563918 DOI: 10.1021/bi800152j  0.88
2008 Ghidu VP, Wang J, Wu B, Liu Q, Jacobs A, Marnett LJ, Sulikowski GA. Synthesis and evaluation of the cytotoxicity of apoptolidinones A and D. The Journal of Organic Chemistry. 73: 4949-55. PMID 18543990 DOI: 10.1021/jo800545r  0.88
2008 Knutson CG, Skipper PL, Liberman RG, Tannenbaum SR, Marnett LJ. Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry. Chemical Research in Toxicology. 21: 1290-4. PMID 18461974 DOI: 10.1021/tx800049v  0.88
2008 Turman MV, Kingsley PJ, Rouzer CA, Cravatt BF, Marnett LJ. Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine. Biochemistry. 47: 3917-25. PMID 18311922 DOI: 10.1021/bi702530z  0.88
2008 Rouzer CA, Marnett LJ. Non-redundant functions of cyclooxygenases: Oxygenation of endocannabinoids Journal of Biological Chemistry. 283: 8065-8069. PMID 18250160 DOI: 10.1074/jbc.R800005200  0.88
2008 Bala M, Chin CN, Logan AT, Amin T, Marnett LJ, Boutaud O, Oates JA. Acetylation of prostaglandin H2 synthases by aspirin is inhibited by redox cycling of the peroxidase. Biochemical Pharmacology. 75: 1472-81. PMID 18242581 DOI: 10.1016/j.bcp.2007.12.005  0.88
2008 Vila A, Tallman KA, Jacobs AT, Liebler DC, Porter NA, Marnett LJ. Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives. Chemical Research in Toxicology. 21: 432-44. PMID 18232660 DOI: 10.1021/tx700347w  0.88
2008 Szekely J, Rizzo CJ, Marnett LJ. Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation. Journal of the American Chemical Society. 130: 2195-201. PMID 18225895 DOI: 10.1021/ja074506u  0.88
2008 Szekely J, Wang H, Peplowski KM, Knutson CG, Marnett LJ, Rizzo CJ. "One-pot" syntheses of malondialdehyde adducts of nucleosides. Nucleosides, Nucleotides & Nucleic Acids. 27: 103-9. PMID 18205065 DOI: 10.1080/15257770701795797  0.88
2008 Stafford JB, Marnett LJ. Prostaglandin E2 inhibits tumor necrosis factor-alpha RNA through PKA type I Biochemical and Biophysical Research Communications. 366: 104-109. PMID 18060853 DOI: 10.1016/j.bbrc.2007.11.091  0.88
2007 Kingsley PJ, Marnett LJ. LC-MS-MS Analysis of Neutral Eicosanoids Methods in Enzymology. 433: 91-112. PMID 17954230 DOI: 10.1016/S0076-6879(07)33005-X  0.88
2007 Knutson CG, Wang H, Rizzo CJ, Marnett LJ. Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-β-D-erythropentofuranosyl)-pyrimido[1,2-α]purine-10(3H) -one, in the rat Journal of Biological Chemistry. 282: 36257-36264. PMID 17951255 DOI: 10.1074/jbc.M706814200  0.88
2007 Druckova A, Mernaugh RL, Ham AJL, Marnett LJ. Identification of the protein targets of the reactive metabolite of teucrin A in vivo in the rat Chemical Research in Toxicology. 20: 1393-1408. PMID 17892266 DOI: 10.1021/tx7001405  0.88
2007 Jacobs AT, Marnett LJ. Heat shock factor 1 attenuates 4-Hydroxynonenal-mediated apoptosis: critical role for heat shock protein 70 induction and stabilization of Bcl-XL. The Journal of Biological Chemistry. 282: 33412-20. PMID 17873279 DOI: 10.1074/jbc.M706799200  0.88
2007 Marnett LJ. AuthorChoice: A great way to get your papers read Chemical Research in Toxicology. 20: 1235-1236. PMID 17867719 DOI: 10.1021/tx700236f  0.88
2007 Joo M, Kwon M, Sadikot RT, Kingsley PJ, Marnett LJ, Blackwell TS, Peebles RS, Urade Y, Christman JW. Induction and function of lipocalin prostaglandin D synthase in host immunity Journal of Immunology. 179: 2565-2575. PMID 17675519  0.88
2007 Harman CA, Turman MV, Kozak KR, Marnett LJ, Smith WL, Garavito RM. Structural basis of enantioselective inhibition of cyclooxygenase-1 by S-alpha-substituted indomethacin ethanolamides. The Journal of Biological Chemistry. 282: 28096-105. PMID 17656360 DOI: 10.1074/jbc.M701335200  0.88
2007 Vila A, Rosengarth A, Piomelli D, Cravatt B, Marnett LJ. Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase. Biochemistry. 46: 9578-85. PMID 17649977 DOI: 10.1021/bi7005898  0.88
2007 Wang Y, Schnetz-Boutaud NC, Saleh S, Marnett LJ, Stone MP. Bulge migration of the malondialdehdye OPdG DNA adduct when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene Chemical Research in Toxicology. 20: 1200-1210. PMID 17645303 DOI: 10.1021/tx700121j  0.88
2007 Jacobs AT, Marnett LJ. The future of toxicology--wrap up. Chemical Research in Toxicology. 20: 983-5. PMID 17630814 DOI: 10.1021/tx7001564  0.88
2007 Felts AS, Ji C, Stafford JB, Crews BC, Kingsley PJ, Rouzer CA, Washington MK, Subbaramaiah K, Siegel BS, Young SM, Dannenberg AJ, Marnett LJ. Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology. Acs Chemical Biology. 2: 479-83. PMID 17602619 DOI: 10.1021/cb700077z  0.88
2007 Prusakiewicz JJ, Turman MV, Vila A, Ball HL, Al-Mestarihi AH, Di Marzo V, Marnett LJ. Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases. Archives of Biochemistry and Biophysics. 464: 260-8. PMID 17493578 DOI: 10.1016/j.abb.2007.04.007  0.88
2007 Rouzer CA, Ivanova PT, Byrne MO, Brown HA, Marnett LJ. Lipid profiling reveals glycerophospholipid remodeling in zymosan-stimulated macrophages Biochemistry. 46: 6026-6042. PMID 17458939 DOI: 10.1021/bi0621617  0.88
2007 Blobaum AL, Marnett LJ. Molecular determinants for the selective inhibition of cyclooxygenase-2 by lumiracoxib Journal of Biological Chemistry. 282: 16379-16390. PMID 17434872 DOI: 10.1074/jbc.M609883200  0.88
2007 Trostchansky A, O'Donnell VB, Goodwin DC, Landino LM, Marnett LJ, Radi R, Rubbo H. Interactions between nitric oxide and peroxynitrite during prostaglandin endoperoxide H synthase-1 catalysis: A free radical mechanism of inactivation Free Radical Biology and Medicine. 42: 1029-1038. PMID 17349930 DOI: 10.1016/j.freeradbiomed.2007.01.009  0.88
2007 Blobaum AL, Marnett LJ. Structural and functional basis of cyclooxygenase inhibition Journal of Medicinal Chemistry. 50: 1425-1441. PMID 17341061 DOI: 10.1021/jm0613166  0.88
2007 Knutson CG, Akingbade D, Crews BC, Voehler M, Stec DF, Marnett LJ. Metabolism in vitro and in vivo of the DNA base adduct, M1G Chemical Research in Toxicology. 20: 550-557. PMID 17311424 DOI: 10.1021/tx600334x  0.88
2007 Wang H, Xie H, Sun X, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK. Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. Prostaglandins & Other Lipid Mediators. 83: 62-74. PMID 17259073 DOI: 10.1016/j.prostaglandins.2006.09.009  0.88
2007 Yu Y, Fan J, Hui Y, Rouzer CA, Marnett LJ, Klein-Szanto AJ, FitzGerald GA, Funk CD. Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality. The Journal of Biological Chemistry. 282: 1498-506. PMID 17110378 DOI: 10.1074/jbc.M609930200  0.88
2007 Adams TB, McGowen MM, Williams MC, Cohen SM, Feron VJ, Goodman JI, Marnett LJ, Munro IC, Portoghese PS, Smith RL, Waddell WJ. The FEMA GRAS assessment of aromatic substituted secondary alcohols, ketones, and related esters used as flavor ingredients. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 45: 171-201. PMID 17046133 DOI: 10.1016/j.fct.2006.07.029  0.88
2007 Marnett LJ. 20th Anniversary Issue Editorial Chemical Research in Toxicology. 20: 1-2. DOI: 10.1021/tx600323j  0.88
2007 Waddell WJ, Cohen SM, Feron VJ, Goodman JI, Marnett LJ, Portoghese PS, Rietjens IMCM, Smith RL, Adams TB, Lucas Gavin C, McGowen MM, Williams MC. GRAS flavoring substances 23 Food Technology. 61: 22-28.  0.88
2006 Rouzer CA, Ivanova PT, Byrne MO, Milne SB, Marnett LJ, Brown HA. Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications Biochemistry. 45: 14795-14808. PMID 17144673 DOI: 10.1021/bi061723j  0.88
2006 Wang H, Kozekov ID, Kozekova A, Tamura PJ, Marnett LJ, Harris TM, Rizzo CJ. Site-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy. Chemical Research in Toxicology. 19: 1467-74. PMID 17112234 DOI: 10.1021/tx060137o  0.88
2006 Druckova A, Marnett LJ. Characterization of the amino acid adducts of the enedial derivative of teucrin A Chemical Research in Toxicology. 19: 1330-1340. PMID 17040102 DOI: 10.1021/tx060143k  0.88
2006 Anning PB, Coles B, Morton J, Wang H, Uddin J, Morrow JD, Dey SK, Marnett LJ, O'Donnell VB. Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors. Blood. 108: 4059-62. PMID 16931629 DOI: 10.1182/blood-2006-02-005330  0.88
2006 Wang H, Xie H, Guo Y, Zhang H, Takahashi T, Kingsley PJ, Marnett LJ, Das SK, Cravatt BF, Dey SK. Fatty acid amide hydrolase deficiency limits early pregnancy events. The Journal of Clinical Investigation. 116: 2122-31. PMID 16886060 DOI: 10.1172/JCI28621  0.88
2006 Feng Z, Hu W, Marnett LJ, Tang Ms. Malondialdehyde, a major endogenous lipid peroxidation product, sensitizes human cells to UV- and BPDE-induced killing and mutagenesis through inhibition of nucleotide excision repair Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 601: 125-136. PMID 16872641 DOI: 10.1016/j.mrfmmm.2006.06.003  0.88
2006 Rouzer CA, Tranguch S, Wang H, Zhang H, Dey SK, Marnett LJ. Zymosan-induced glycerylprostaglandin and prostaglandin synthesis in resident peritoneal macrophages: Roles of cyclo-oxygenase-1 and -2 Biochemical Journal. 399: 91-99. PMID 16787386 DOI: 10.1042/BJ20060615  0.88
2006 Otteneder MB, Knutson CG, Daniels JS, Hashim M, Crews BC, Remmel RP, Wang H, Rizzo C, Marnett LJ. In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG Proceedings of the National Academy of Sciences of the United States of America. 103: 6665-6669. PMID 16614064 DOI: 10.1073/pnas.0602017103  0.88
2006 West JD, Marnett LJ. Endogenous reactive intermediates as modulators of cell signaling and cell death. Chemical Research in Toxicology. 19: 173-94. PMID 16485894 DOI: 10.1021/tx050321u  0.88
2006 Muthian G, Raikwar HP, Johnson C, Rajasingh J, Kalgutkar A, Marnett LJ, Bright JJ. COX-2 inhibitors modulate IL-12 signaling through JAK-STAT pathway leading to Th1 response in experimental allergic encephalomyelitis. Journal of Clinical Immunology. 26: 73-85. PMID 16418805 DOI: 10.1007/s10875-006-8787-y  0.88
2005 West JD, Marnett LJ. Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal. Chemical Research in Toxicology. 18: 1642-53. PMID 16300372 DOI: 10.1021/tx050211n  0.88
2005 Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (New York, N.Y.). 310: 329-32. PMID 16224028 DOI: 10.1126/science.1115740  0.88
2005 Kalgutkar AS, Crews BC, Saleh S, Prudhomme D, Marnett LJ. Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors Bioorganic and Medicinal Chemistry. 13: 6810-6822. PMID 16169736 DOI: 10.1016/j.bmc.2005.07.073  0.88
2005 Sander M, Cadet J, Casciano DA, Galloway SM, Marnett LJ, Novak RF, Pettit SD, Preston RJ, Skare JA, Williams GM, Van Houten B, Gollapudi BB. Proceedings of a workshop on DNA adducts: Biological significance and applications to risk assessment Washington, DC, April 13-14, 2004 Toxicology and Applied Pharmacology. 208: 1-20. PMID 16164957 DOI: 10.1016/j.taap.2004.12.012  0.88
2005 Rouzer CA, Marnett LJ. Structural and functional differences between cyclooxygenases: Fatty acid oxygenases with a critical role in cell signaling Biochemical and Biophysical Research Communications. 338: 34-44. PMID 16126167 DOI: 10.1016/j.bbrc.2005.07.198  0.88
2005 Kingsley PJ, Rouzer CA, Saleh S, Marnett LJ. Simultaneous analysis of prostaglandin glyceryl esters and prostaglandins by electrospray tandem mass spectrometry Analytical Biochemistry. 343: 203-211. PMID 16004953 DOI: 10.1016/j.ab.2005.05.005  0.88
2005 Adams TB, Cohen SM, Doull J, Feron VJ, Goodman JI, Marnett LJ, Munro IC, Portoghese PS, Smith RL, Waddell WJ, Wagner BM. The FEMA GRAS assessment of hydroxy- and alkoxy-substituted benzyl derivatives used as flavor ingredients. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 43: 1241-71. PMID 15950816 DOI: 10.1016/j.fct.2004.12.018  0.88
2005 Adams TB, Cohen SM, Doull J, Feron VJ, Goodman JI, Marnett LJ, Munro IC, Portoghese PS, Smith RL, Waddell WJ, Wagner BM. The FEMA GRAS assessment of benzyl derivatives used as flavor ingredients. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 43: 1207-40. PMID 15950815 DOI: 10.1016/j.fct.2004.11.014  0.88
2005 Adams TB, Cohen SM, Doull J, Feron VJ, Goodman JI, Marnett LJ, Munro IC, Portoghese PS, Smith RL, Waddell WJ, Wagner BM. The FEMA GRAS assessment of phenethyl alcohol, aldehyde, acid, and related acetals and esters used as flavor ingredients. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 43: 1179-206. PMID 15950814 DOI: 10.1016/j.fct.2004.11.013  0.88
2005 Smith RL, Cohen SM, Doull J, Feron VJ, Goodman JI, Marnett LJ, Munro IC, Portoghese PS, Waddell WJ, Wagner BM, Adams TB. Criteria for the safety evaluation of flavoring substances. The Expert Panel of the Flavor and Extract Manufacturers Association. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 43: 1141-77. PMID 15950813 DOI: 10.1016/j.fct.2004.11.012  0.88
2005 Burleigh ME, Babaev VR, Patel MB, Crews BC, Remmel RP, Morrow JD, Oates JA, Marnett LJ, Fazio S, Linton MF. Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice Biochemical Pharmacology. 70: 334-342. PMID 15950196 DOI: 10.1016/j.bcp.2005.04.044  0.88
2005 Guo Y, Wang H, Okamoto Y, Ueda N, Kingsley PJ, Marnett LJ, Schmid HHO, Das SK, Dey SK. N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation Journal of Biological Chemistry. 280: 23429-23432. PMID 15890658 DOI: 10.1074/jbc.C500168200  0.88
2005 Moth CW, Prusakiewicz JJ, Marnett LJ, Lybrand TP. Stereoselective binding of indomethacin ethanolamide derivatives to cyclooxygenase-1 Journal of Medicinal Chemistry. 48: 3613-3620. PMID 15887968 DOI: 10.1021/jm0494164  0.88
2005 VanderVeen LA, Druckova A, Riggins JN, Sorrells JL, Guengerich FP, Marnett LJ. Differential DNA recognition and cleavage by EcoRI dependent on the dynamic equilibrium between the two forms of the malondialdehyde-deoxyguanosine adduct Biochemistry. 44: 5024-5033. PMID 15794640 DOI: 10.1021/bi0472898  0.88
2005 Vélez-Cruz R, Riggins JN, Daniels JS, Cai H, Guengerich FP, Marnett LJ, Osheroff N. Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase IIα in vitro and in cultured cells Biochemistry. 44: 3972-3981. PMID 15751973 DOI: 10.1021/bi0478289  0.88
2005 Rouzer CA, Jacobs AT, Nirodi CS, Kingsley PJ, Morrow JD, Marnett LJ. RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-alpha secretion. Journal of Lipid Research. 46: 1027-37. PMID 15722559 DOI: 10.1194/jlr.M500006-JLR200  0.88
2005 Kadiiska MB, Gladen BC, Baird DD, Graham LB, Parker CE, Ames BN, Basu S, Fitzgerald GA, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ, Rokach J, et al. Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radical Biology & Medicine. 38: 711-8. PMID 15721981 DOI: 10.1016/j.freeradbiomed.2004.10.024  0.88
2005 Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, ... ... Marnett LJ, et al. Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radical Biology & Medicine. 38: 698-710. PMID 15721980 DOI: 10.1016/j.freeradbiomed.2004.09.017  0.88
2005 West JD, Ji C, Marnett LJ. Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1. The Journal of Biological Chemistry. 280: 15141-7. PMID 15703174 DOI: 10.1074/jbc.M413147200  0.88
2005 Smith RL, Cohen SM, Doull J, Feron VJ, Goodman JI, Marnett LJ, Portoghese PS, Waddell WJ, Wagner BM, Hall RL, Higley NA, Lucas-Gavin C, Adams TB. A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 43: 345-63. PMID 15680674 DOI: 10.1016/j.fct.2004.11.007  0.88
2005 Hata AN, Lybrand TP, Marnett LJ, Breyer RM. Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2 Molecular Pharmacology. 67: 640-647. PMID 15563582 DOI: 10.1124/mol.104.007971  0.88
2005 Clark SR, Anning PB, Coffey MJ, Roberts AG, Marnett LJ, O'Donnell VB. Depletion of iNOS-derived nitric oxide by prostaglandin H synthase-2 in inflammation-activated J774.2 macrophages through lipohydroperoxidase turnover. The Biochemical Journal. 385: 815-21. PMID 15461587 DOI: 10.1042/BJ20041353  0.88
2005 Marnett LJ. Open access publication: One editor's opinion Chemical Research in Toxicology. 18: 787-789. DOI: 10.1021/tx0500934  0.88
2005 Smith RL, Cohen SM, Doull J, Feron VJ, Goodman JI, Marnett LJ, Portoghese PS, Waddell WJ, Wagner BM, Adams TB. GRAS flavoring substances 22 Food Technology. 59: 24-62.  0.88
1980 Porter NA, Wolf RA, Pagels WR, Marnett LJ. A test for the intermediacy of 11-hydroperoxyeicosa-5,8,12,14-tetraenoic acid [11-HPETE] in prostaglandin biosynthesis. Biochemical and Biophysical Research Communications. 92: 349-55. PMID 6766722  0.52
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