Stephen L. Buchwald - Publications

Affiliations: 
1984- Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
organometallic chemistry
Website:
http://chemistry.mit.edu/people/buchwald-stephen

325 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ichikawa S, Dai XJ, Buchwald SL. Regio- and Enantioselective Synthesis of 1,2-Diamine Derivatives by Copper-Catalyzed Hydroamination. Organic Letters. PMID 31099584 DOI: 10.1021/acs.orglett.9b01592  0.48
2019 Li C, Liu RY, Jesikiewicz LT, Yang Y, Liu P, Buchwald SL. CuH-Catalyzed Enantioselective Ketone Allylation with 1,3-Dienes: Scope, Mechanism, and Applications. Journal of the American Chemical Society. PMID 30817137 DOI: 10.1021/jacs.9b01784  1
2019 Ye Y, Kim ST, Jeong J, Baik MH, Buchwald SL. CuH-Catalyzed Enantioselective Alkylation of Indole Derivatives with Ligand-Controlled Regiodivergence. Journal of the American Chemical Society. PMID 30696242 DOI: 10.1021/jacs.8b11838  0.48
2019 Liu RY, Zhou Y, Yang Y, Buchwald SL. Enantioselective Allylation Using Allene, a Petroleum Cracking Byproduct. Journal of the American Chemical Society. PMID 30685967 DOI: 10.1021/jacs.8b13907  1
2019 Dai XJ, Engl OD, León T, Buchwald SL. Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles. Angewandte Chemie (International Ed. in English). PMID 30659729 DOI: 10.1002/anie.201814331  0.88
2018 Pentelute B, Zhang C, Vinogradova E, Spokoyny A, Buchwald S. Arylation Chemistry for Bioconjugation. Angewandte Chemie (International Ed. in English). PMID 30399206 DOI: 10.1002/anie.201806009  0.96
2018 Cohen DT, Zhang C, Fadzen CM, Mijalis AJ, Hie L, Johnson KD, Shriver Z, Plante O, Miller SJ, Buchwald SL, Pentelute BL. A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins. Nature Chemistry. PMID 30397320 DOI: 10.1038/s41557-018-0154-0  1
2018 Guo S, Yang JC, Buchwald SL. A Practical Electrophilic Nitrogen Source for the Synthesis of Chiral Primary Amines by Copper-Catalyzed Hydroamination. Journal of the American Chemical Society. PMID 30371077 DOI: 10.1021/jacs.8b10564  0.84
2018 Liu RY, Buchwald SL. Copper-Catalyzed Enantioselective Hydroamination of Alkenes. Organic Syntheses; An Annual Publication of Satisfactory Methods For the Preparation of Organic Chemicals. 95: 80-96. PMID 30287975 DOI: 10.15227/orgsyn.095.0080  1
2018 Thomas AA, Speck K, Kevlishvili I, Lu Z, Liu P, Buchwald SL. Mechanistically Guided Design of Ligands that Significantly Improve the Efficiency of CuH-Catalyzed Hydroamination Reactions. Journal of the American Chemical Society. PMID 30244567 DOI: 10.1021/jacs.8b09565  0.84
2018 Buchwald SL, Khan RKM, Zhao Y, Scully T. Catalytic Arylhydroxylation of Dehydroalanine in Continuous Flow for Simple Access to Unnatural Amino Acids. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30102444 DOI: 10.1002/chem.201804094  0.72
2018 Ichikawa S, Zhu S, Buchwald SL. A Modified System for the Synthesis of Enantioenriched N-Arylamines through Copper-Catalyzed Hydroamination. Angewandte Chemie (International Ed. in English). PMID 29847002 DOI: 10.1002/anie.201803026  1
2018 Shi SL, Wong ZL, Buchwald SL. Addendum: Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols. Nature. PMID 29795353 DOI: 10.1038/s41586-018-0112-4  0.84
2018 Tsai EY, Liu RY, Yang Y, Buchwald SL. Correction to "A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes". Journal of the American Chemical Society. PMID 29737849 DOI: 10.1021/jacs.8b04366  1
2018 Zhou Y, Engl OD, Bandar JS, Chant ED, Buchwald SL. CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes. Angewandte Chemie (International Ed. in English). PMID 29660768 DOI: 10.1002/anie.201802797  1
2018 Gribble MW, Guo S, Buchwald SL. Asymmetric Cu-Catalyzed 1,4-Dearomatization of Pyridines and Pyridazines without Preactivation of the Heterocycle or Nucleophile. Journal of the American Chemical Society. PMID 29609461 DOI: 10.1021/jacs.8b02568  0.8
2018 Dennis JM, White NA, Liu RY, Buchwald SL. Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common, Soluble Base in C-N Coupling. Journal of the American Chemical Society. PMID 29529363 DOI: 10.1021/jacs.8b01696  1
2018 Zhang H, Ruiz-Castillo P, Buchwald SL. Palladium-Catalyzed C-O Cross-Coupling of Primary Alcohols. Organic Letters. PMID 29474078 DOI: 10.1021/acs.orglett.8b00325  1
2018 Kubota K, Dai P, Pentelute BL, Buchwald SL. Palladium Oxidative Addition Complexes for Peptide and Protein Crosslinking. Journal of the American Chemical Society. PMID 29406701 DOI: 10.1021/jacs.8b00172  0.96
2018 Tsai E, Liu RY, Yang Y, Buchwald SL. A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes. Journal of the American Chemical Society. PMID 29376366 DOI: 10.1021/jacs.7b12271  1
2018 Liu RY, Bae M, Buchwald SL. Mechanistic Insight Facilitates Discovery of a Mild and Efficient Copper-Catalyzed Dehydration of Primary Amides to Nitriles Using Hydrosilanes. Journal of the American Chemical Society. PMID 29353477 DOI: 10.1021/jacs.8b00643  1
2018 Zhou Y, Bandar JS, Liu RY, Buchwald SL. CuH-Catalyzed Asymmetric Reduction of α,β-Unsaturated Carboxylic Acids to β-Chiral Aldehydes. Journal of the American Chemical Society. PMID 29283578 DOI: 10.1021/jacs.7b12260  1
2017 Rojas AJ, Zhang C, Vinogradova EV, Buchwald NH, Reilly J, Pentelute BL, Buchwald SL. Divergent unprotected peptide macrocyclisation by palladium-mediated cysteine arylation. Chemical Science. 8: 4257-4263. PMID 29081961 DOI: 10.1039/c6sc05454d  0.96
2017 Lu G, Liu RY, Yang Y, Fang C, Lambrecht DS, Buchwald SL, Liu P. Ligand-Substrate Dispersion Facilitates the Copper-Catalyzed Hydroamination of Unactivated Olefins. Journal of the American Chemical Society. PMID 29064694 DOI: 10.1021/jacs.7b07373  1
2017 Rojas AJ, Pentelute BL, Buchwald SL. Water-Soluble Palladium Reagents for Cysteine S-Arylation under Ambient Aqueous Conditions. Organic Letters. PMID 28777001 DOI: 10.1021/acs.orglett.7b01911  0.96
2017 Zhang H, Buchwald SL. Palladium-Catalyzed Negishi Coupling of α-CF3 Oxiranyl Zincate: Access to Chiral CF3-substituted Benzylic Tertiary Alcohols. Journal of the American Chemical Society. PMID 28753004 DOI: 10.1021/jacs.7b06630  1
2017 Wang H, Yang JC, Buchwald SL. CuH-Catalyzed Regioselective Intramolecular Hydroamination for the Synthesis of Alkyl-Substituted Chiral Aziridines. Journal of the American Chemical Society. PMID 28594548 DOI: 10.1021/jacs.7b04816  0.84
2017 Zhou Y, Bandar JS, Buchwald SL. Enantioselective CuH-Catalyzed Hydroacylation Employing Unsaturated Carboxylic Acids as Aldehyde Surrogates. Journal of the American Chemical Society. 139: 8126-8129. PMID 28565905 DOI: 10.1021/jacs.7b04937  1
2017 Friis SD, Pirnot MT, Dupuis LN, Buchwald SL. A Dual Palladium and Copper Hydride Catalyzed Approach for Alkyl-Aryl Cross-Coupling of Aryl Halides and Olefins. Angewandte Chemie (International Ed. in English). 56: 7242-7246. PMID 28510287 DOI: 10.1002/anie.201703400  1
2017 Zhao W, Lee HG, Buchwald SL, Hooker JM. Direct (11)CN-Labeling of Unprotected Peptides via Palladium-Mediated Sequential Cross-Coupling Reactions. Journal of the American Chemical Society. 139: 7152-7155. PMID 28502164 DOI: 10.1021/jacs.7b02761  0.96
2017 Ingoglia BT, Buchwald SL. Oxidative Addition Complexes as Precatalysts for Cross-Coupling Reactions Requiring Extremely Bulky Biarylphosphine Ligands. Organic Letters. 19: 2853-2856. PMID 28498667 DOI: 10.1021/acs.orglett.7b01082  1
2017 Lee HG, Lautrette G, Pentelute BL, Buchwald SL. Palladium-Mediated Arylation of Lysine in Unprotected Peptides. Angewandte Chemie (International Ed. in English). 56: 3177-3181. PMID 28206688 DOI: 10.1002/anie.201611202  0.96
2017 Gribble MW, Pirnot MT, Bandar JS, Liu RY, Buchwald SL. Asymmetric Copper Hydride-Catalyzed Markovnikov Hydrosilylation of Vinylarenes and Vinyl Heterocycles. Journal of the American Chemical Society. 139: 2192-2195. PMID 28117996 DOI: 10.1021/jacs.6b13029  1
2016 Reizman BJ, Wang YM, Buchwald SL, Jensen KF. Suzuki-Miyaura cross-coupling optimization enabled by automated feedback. Reaction Chemistry & Engineering. 1: 658-666. PMID 27928513 DOI: 10.1039/c6re00153j  1
2016 Ye Y, Takada T, Buchwald SL. Palladium-Catalyzed Fluorination of Cyclic Vinyl Triflates: Effect of TESCF3 as an Additive. Angewandte Chemie (International Ed. in English). 55: 15559-15563. PMID 27862732 DOI: 10.1002/anie.201608927  0.48
2016 Liu RY, Yang Y, Buchwald SL. Regiodivergent and Diastereoselective CuH-Catalyzed Allylation of Imines with Terminal Allenes. Angewandte Chemie (International Ed. in English). 55: 14077-14080. PMID 27723269 DOI: 10.1002/anie.201608446  1
2016 Ruiz-Castillo P, Buchwald SL. Applications of Palladium-Catalyzed C-N Cross-Coupling Reactions. Chemical Reviews. 116: 12564-12649. PMID 27689804 DOI: 10.1021/acs.chemrev.6b00512  0.64
2016 Sather AC, Buchwald SL. The Evolution of Pd(0)/Pd(II)-Catalyzed Aromatic Fluorination. Accounts of Chemical Research. 49: 2146-2157. PMID 27656765 DOI: 10.1021/acs.accounts.6b00247  1
2016 Park NH, Senter TJ, Buchwald SL. Rapid Synthesis of Aryl Fluorides in Continuous Flow through the Balz-Schiemann Reaction. Angewandte Chemie (International Ed. in English). 55: 11907-11. PMID 27558308 DOI: 10.1002/anie.201606601  0.88
2016 Vincent BM, Langlois JB, Srinivas R, Lancaster AK, Scherz-Shouval R, Whitesell L, Tidor B, Buchwald SL, Lindquist S. A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance. Cell Chemical Biology. 23: 978-991. PMID 27524297 DOI: 10.1016/j.chembiol.2016.06.016  0.32
2016 King SM, Buchwald SL. Development of a Method for the N-Arylation of Amino Acid Esters with Aryl Triflates. Organic Letters. 18: 4128-31. PMID 27498618 DOI: 10.1021/acs.orglett.6b02082  0.92
2016 Huang W, Buchwald SL. Palladium-Catalyzed N-Arylation of Iminodibenzyls and Iminostilbenes with Aryl- and Heteroaryl Halides. Chemistry (Weinheim An Der Bergstrasse, Germany). 22: 14186-9. PMID 27481439 DOI: 10.1002/chem.201603449  1
2016 Roesner S, Buchwald SL. Continuous-Flow Synthesis of Biaryls by Negishi Cross-Coupling of Fluoro- and Trifluoromethyl-Substituted (Hetero)arenes. Angewandte Chemie (International Ed. in English). 55: 10463-7. PMID 27456275 DOI: 10.1002/anie.201605584  1
2016 Yang Y, Perry IB, Buchwald SL. Copper-Catalyzed Enantioselective Addition of Styrene-Derived Nucleophiles to Imines Enabled by Ligand-Controlled Chemoselective Hydrocupration. Journal of the American Chemical Society. 138: 9787-90. PMID 27454393 DOI: 10.1021/jacs.6b06299  1
2016 Friis SD, Pirnot MT, Buchwald SL. Asymmetric Hydroarylation of Vinylarenes Using a Synergistic Combination of CuH and Pd Catalysis. Journal of the American Chemical Society. 138: 8372-5. PMID 27346525 DOI: 10.1021/jacs.6b04566  1
2016 Corcoran EB, Pirnot MT, Lin S, Dreher SD, DiRocco DA, Davies IW, Buchwald SL, MacMillan DW. Aryl amination using ligand-free Ni(II) salts and photoredox catalysis. Science (New York, N.Y.). 353: 279-83. PMID 27338703 DOI: 10.1126/science.aag0209  1
2016 Yang Y, Perry IB, Lu G, Liu P, Buchwald SL. Copper-catalyzed asymmetric addition of olefin-derived nucleophiles to ketones. Science (New York, N.Y.). 353: 144-50. PMID 27284169 DOI: 10.1126/science.aaf7720  1
2016 Bandar JS, Ascic E, Buchwald SL. Enantioselective CuH-Catalyzed Reductive Coupling of Aryl Alkenes and Activated Carboxylic Acids. Journal of the American Chemical Society. 138: 5821-4. PMID 27121395 DOI: 10.1021/jacs.6b03086  1
2016 Wang YM, Buchwald SL. Enantioselective CuH-Catalyzed Hydroallylation of Vinylarenes. Journal of the American Chemical Society. 138: 5024-7. PMID 27042864 DOI: 10.1021/jacs.6b02527  1
2016 Shi SL, Wong ZL, Buchwald SL. Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols. Nature. 532: 353-6. PMID 27018656 DOI: 10.1038/nature17191  0.84
2016 Zhu S, Niljianskul N, Buchwald SL. A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination. Nature Chemistry. 8: 144-50. PMID 26791897 DOI: 10.1038/nchem.2418  1
2016 Yang JC, Niu D, Karsten BP, Lima F, Buchwald SL. Use of a "Catalytic" Cosolvent, N,N-Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch. Angewandte Chemie (International Ed. in English). 55: 2531-5. PMID 26756279 DOI: 10.1002/anie.201509922  1
2016 Pirnot MT, Wang YM, Buchwald SL. Copper Hydride Catalyzed Hydroamination of Alkenes and Alkynes. Angewandte Chemie (International Ed. in English). 55: 48-57. PMID 26661678 DOI: 10.1002/anie.201507594  1
2015 Milner PJ, Yang Y, Buchwald SL. In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides. Organometallics. 34: 4775-4780. PMID 27056379 DOI: 10.1021/acs.organomet.5b00631  1
2015 Bandar JS, Pirnot MT, Buchwald SL. Mechanistic Studies Lead to Dramatically Improved Reaction Conditions for the Cu-Catalyzed Asymmetric Hydroamination of Olefins. Journal of the American Chemical Society. 137: 14812-8. PMID 26522837 DOI: 10.1021/jacs.5b10219  1
2015 Vinogradova EV, Zhang C, Spokoyny AM, Pentelute BL, Buchwald SL. Organometallic palladium reagents for cysteine bioconjugation. Nature. 526: 687-91. PMID 26511579 DOI: 10.1038/nature15739  0.96
2015 Sather AC, Lee HG, De La Rosa VY, Yang Y, Müller P, Buchwald SL. A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides. Journal of the American Chemical Society. 137: 13433-8. PMID 26413908 DOI: 10.1021/jacs.5b09308  1
2015 Sather AC, Lee HG, Colombe JR, Zhang A, Buchwald SL. Dosage delivery of sensitive reagents enables glove-box-free synthesis. Nature. 524: 208-11. PMID 26268191 DOI: 10.1038/nature14654  1
2015 Wang YM, Bruno NC, Placeres ÁL, Zhu S, Buchwald SL. Enantioselective Synthesis of Carbo- and Heterocycles through a CuH-Catalyzed Hydroalkylation Approach. Journal of the American Chemical Society. 137: 10524-7. PMID 26256576 DOI: 10.1021/jacs.5b07061  1
2015 Cohen DT, Zhang C, Pentelute BL, Buchwald SL. An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides. Journal of the American Chemical Society. 137: 9784-7. PMID 26225900 DOI: 10.1021/jacs.5b05447  1
2015 Niu D, Buchwald SL. Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination. Journal of the American Chemical Society. 137: 9716-21. PMID 26144542 DOI: 10.1021/jacs.5b05446  1
2015 Yang Y, Shi SL, Niu D, Liu P, Buchwald SL. ORGANIC CHEMISTRY. Catalytic asymmetric hydroamination of unactivated internal olefins to aliphatic amines. Science (New York, N.Y.). 349: 62-6. PMID 26138973 DOI: 10.1126/science.aab3753  1
2015 Zhu R, Buchwald SL. Versatile Enantioselective Synthesis of Functionalized Lactones via Copper-Catalyzed Radical Oxyfunctionalization of Alkenes. Journal of the American Chemical Society. 137: 8069-77. PMID 26070105 DOI: 10.1021/jacs.5b04821  1
2015 Colombe JR, DeBergh JR, Buchwald SL. Synthesis of Heteroaryl Sulfonamides from Organozinc Reagents and 2,4,6-Trichlorophenyl Chlorosulfate. Organic Letters. 17: 3170-3. PMID 26065317 DOI: 10.1021/acs.orglett.5b01540  0.92
2015 Park NH, Vinogradova EV, Surry DS, Buchwald SL. Design of New Ligands for the Palladium-Catalyzed Arylation of α-Branched Secondary Amines. Angewandte Chemie (International Ed. in English). 54: 8259-62. PMID 26032920 DOI: 10.1002/anie.201502626  1
2015 Ascic E, Buchwald SL. Highly diastereo- and enantioselective CuH-catalyzed synthesis of 2,3-disubstituted indolines. Journal of the American Chemical Society. 137: 4666-9. PMID 25826004 DOI: 10.1021/jacs.5b02316  0.48
2015 Ruiz-Castillo P, Blackmond DG, Buchwald SL. Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis. Journal of the American Chemical Society. 137: 3085-92. PMID 25651374 DOI: 10.1021/ja512903g  0.76
2015 Lee HG, Milner PJ, Placzek MS, Buchwald SL, Hooker JM. Virtually instantaneous, room-temperature [(11)C]-cyanation using biaryl phosphine Pd(0) complexes. Journal of the American Chemical Society. 137: 648-51. PMID 25565277 DOI: 10.1021/ja512115s  1
2015 Cohen DT, Buchwald SL. Mild palladium-catalyzed cyanation of (hetero)aryl halides and triflates in aqueous media. Organic Letters. 17: 202-5. PMID 25555140 DOI: 10.1021/ol5032359  1
2015 Shi SL, Buchwald SL. Copper-catalysed selective hydroamination reactions of alkynes. Nature Chemistry. 7: 38-44. PMID 25515888 DOI: 10.1038/nchem.2131  0.84
2015 Shi SL, Buchwald SL. Palladium-catalyzed intramolecular C-H difluoroalkylation: synthesis of substituted 3,3-difluoro-2-oxindoles. Angewandte Chemie (International Ed. in English). 54: 1646-50. PMID 25476241 DOI: 10.1002/anie.201410471  0.84
2015 Niljianskul N, Zhu S, Buchwald SL. Enantioselective synthesis of α-aminosilanes by copper-catalyzed hydroamination of vinylsilanes. Angewandte Chemie (International Ed. in English). 54: 1638-41. PMID 25475991 DOI: 10.1002/anie.201410326  1
2015 Chen M, Ichikawa S, Buchwald SL. Rapid and efficient copper-catalyzed Finkelstein reaction of (hetero)aromatics under continuous-flow conditions. Angewandte Chemie (International Ed. in English). 54: 263-6. PMID 25378244 DOI: 10.1002/anie.201409595  1
2015 Cohen DT, Zhang C, Pentelute BL, Buchwald SL. An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides Journal of the American Chemical Society. 137: 9784-9787. DOI: 10.1021/jacs.5b05447  1
2015 Milner PJ, Yang Y, Buchwald SL. In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides Organometallics. 34: 4775-4780. DOI: 10.1021/acs.organomet.5b00631  1
2014 Lee HG, Milner PJ, Colvin MT, Andreas L, Buchwald SL. Structure and Reactivity of [(L•Pd)n•(1,5-cyclooctadiene)] (n=1-2) Complexes Bearing Biaryl Phosphine Ligands. Inorganica Chimica Acta. 422: 188-192. PMID 25346547 DOI: 10.1016/j.ica.2014.06.008  1
2014 Zhu S, Buchwald SL. Enantioselective CuH-catalyzed anti-Markovnikov hydroamination of 1,1-disubstituted alkenes. Journal of the American Chemical Society. 136: 15913-6. PMID 25339089 DOI: 10.1021/ja509786v  1
2014 Milner PJ, Kinzel T, Zhang Y, Buchwald SL. Studying regioisomer formation in the Pd-catalyzed fluorination of aryl triflates by deuterium labeling. Journal of the American Chemical Society. 136: 15757-66. PMID 25299957 DOI: 10.1021/ja509144r  1
2014 Yang Y, Niedermann K, Han C, Buchwald SL. Highly selective palladium-catalyzed cross-coupling of secondary alkylzinc reagents with heteroaryl halides. Organic Letters. 16: 4638-41. PMID 25153332 DOI: 10.1021/ol502230p  1
2014 Friis SD, Skrydstrup T, Buchwald SL. Mild Pd-catalyzed aminocarbonylation of (hetero)aryl bromides with a palladacycle precatalyst. Organic Letters. 16: 4296-9. PMID 25090373 DOI: 10.1021/ol502014b  0.88
2014 Ernst JB, Tay NE, Jui NT, Buchwald SL. Regioselective synthesis of benzimidazolones via cascade C-N coupling of monosubstituted ureas. Organic Letters. 16: 3844-6. PMID 24971635 DOI: 10.1021/ol501531q  0.84
2014 Yang Y, Buchwald SL. Copper-catalyzed regioselective ortho C-H cyanation of vinylarenes. Angewandte Chemie (International Ed. in English). 53: 8677-81. PMID 24801708 DOI: 10.1002/anie.201402449  1
2014 Cheung CW, Buchwald SL. Palladium-catalyzed hydroxylation of aryl and heteroaryl halides enabled by the use of a palladacycle precatalyst. The Journal of Organic Chemistry. 79: 5351-8. PMID 24762125 DOI: 10.1021/jo500662s  0.72
2014 Bruno NC, Niljianskul N, Buchwald SL. N-substituted 2-aminobiphenylpalladium methanesulfonate precatalysts and their use in C-C and C-N cross-couplings. The Journal of Organic Chemistry. 79: 4161-6. PMID 24724692 DOI: 10.1021/jo500355k  1
2014 Vinogradova EV, Müller P, Buchwald SL. Structural reevaluation of the electrophilic hypervalent iodine reagent for trifluoromethylthiolation supported by the crystalline sponge method for X-ray analysis. Angewandte Chemie (International Ed. in English). 53: 3125-8. PMID 24677728 DOI: 10.1002/anie.201310897  0.92
2014 Zhu Y, Buchwald SL. Ligand-controlled asymmetric arylation of aliphatic α-amino anion equivalents. Journal of the American Chemical Society. 136: 4500-3. PMID 24621247 DOI: 10.1021/ja501560x  1
2014 Lee HG, Milner PJ, Buchwald SL. Pd-catalyzed nucleophilic fluorination of aryl bromides. Journal of the American Chemical Society. 136: 3792-5. PMID 24559304 DOI: 10.1021/ja5009739  1
2014 Su M, Hoshiya N, Buchwald SL. Palladium-catalyzed amination of unprotected five-membered heterocyclic bromides. Organic Letters. 16: 832-5. PMID 24417224 DOI: 10.1021/ol4035947  1
2014 Park NH, Teverovskiy G, Buchwald SL. Development of an air-stable nickel precatalyst for the amination of aryl chlorides, sulfamates, mesylates, and triflates. Organic Letters. 16: 220-3. PMID 24283652 DOI: 10.1021/ol403209k  1
2013 Yang Y, Mustard TJ, Cheong PH, Buchwald SL. Palladium-catalyzed completely linear-selective Negishi cross-coupling of allylzinc halides with aryl and vinyl electrophiles. Angewandte Chemie (International Ed. in English). 52: 14098-102. PMID 24353232 DOI: 10.1002/anie.201308585  1
2013 Tardiff DF, Jui NT, Khurana V, Tambe MA, Thompson ML, Chung CY, Kamadurai HB, Kim HT, Lancaster AK, Caldwell KA, Caldwell GA, Rochet JC, Buchwald SL, Lindquist S. Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science (New York, N.Y.). 342: 979-83. PMID 24158909 DOI: 10.1126/science.1245321  0.84
2013 Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, ... ... Buchwald SL, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/science.1245296  0.84
2013 Colombe JR, Bernhardt S, Stathakis C, Buchwald SL, Knochel P. Synthesis of solid 2-pyridylzinc reagents and their application in Negishi reactions. Organic Letters. 15: 5754-7. PMID 24156393 DOI: 10.1021/ol402798z  0.92
2013 Lee HG, Milner PJ, Buchwald SL. An improved catalyst system for the Pd-catalyzed fluorination of (hetero)aryl triflates. Organic Letters. 15: 5602-5. PMID 24138611 DOI: 10.1021/ol402859k  1
2013 Zhu R, Buchwald SL. Enantioselective functionalization of radical intermediates in redox catalysis: copper-catalyzed asymmetric oxytrifluoromethylation of alkenes. Angewandte Chemie (International Ed. in English). 52: 12655-8. PMID 24133010 DOI: 10.1002/anie.201307790  1
2013 Zhu S, Niljianskul N, Buchwald SL. Enantio- and regioselective CuH-catalyzed hydroamination of alkenes. Journal of the American Chemical Society. 135: 15746-9. PMID 24106781 DOI: 10.1021/ja4092819  1
2013 Chen M, Buchwald SL. Rapid and efficient trifluoromethylation of aromatic and heteroaromatic compounds using potassium trifluoroacetate enabled by a flow system. Angewandte Chemie (International Ed. in English). 52: 11628-31. PMID 24038907 DOI: 10.1002/anie.201306094  1
2013 Jui NT, Buchwald SL. Cascade palladium catalysis: a predictable and selectable regiocontrolled synthesis of N-arylbenzimidazoles. Angewandte Chemie (International Ed. in English). 52: 11624-7. PMID 24038854 DOI: 10.1002/anie.201306007  0.84
2013 Senecal TD, Shu W, Buchwald SL. A general, practical palladium-catalyzed cyanation of (hetero)aryl chlorides and bromides. Angewandte Chemie (International Ed. in English). 52: 10035-9. PMID 23934947 DOI: 10.1002/anie.201304188  1
2013 Düfert MA, Billingsley KL, Buchwald SL. Suzuki-Miyaura cross-coupling of unprotected, nitrogen-rich heterocycles: substrate scope and mechanistic investigation. Journal of the American Chemical Society. 135: 12877-85. PMID 23909907 DOI: 10.1021/ja4064469  1
2013 Cheung CW, Buchwald SL. Mild and general palladium-catalyzed synthesis of methyl aryl ethers enabled by the use of a palladacycle precatalyst. Organic Letters. 15: 3998-4001. PMID 23883393 DOI: 10.1021/ol401796v  0.72
2013 DeBergh JR, Niljianskul N, Buchwald SL. Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids. Journal of the American Chemical Society. 135: 10638-41. PMID 23837740 DOI: 10.1021/ja405949a  1
2013 Yang Y, Buchwald SL. Ligand-controlled palladium-catalyzed regiodivergent Suzuki-Miyaura cross-coupling of allylboronates and aryl halides. Journal of the American Chemical Society. 135: 10642-5. PMID 23837686 DOI: 10.1021/ja405950c  1
2013 Cheung CW, Surry DS, Buchwald SL. Mild and highly selective palladium-catalyzed monoarylation of ammonia enabled by the use of bulky biarylphosphine ligands and palladacycle precatalysts. Organic Letters. 15: 3734-7. PMID 23815096 DOI: 10.1021/ol401612c  1
2013 Bruno NC, Buchwald SL. Synthesis and application of palladium precatalysts that accommodate extremely bulky di-tert-butylphosphino biaryl ligands. Organic Letters. 15: 2876-9. PMID 23675976 DOI: 10.1021/ol401208t  1
2013 Bruno NC, Tudge MT, Buchwald SL. Design and Preparation of New Palladium Precatalysts for C-C and C-N Cross-Coupling Reactions. Chemical Science. 4: 916-920. PMID 23667737 DOI: 10.1039/C2SC20903A  1
2013 Chen M, Buchwald SL. Continuous-flow synthesis of 1-substituted benzotriazoles from chloronitrobenzenes and amines in a C-N bond formation/hydrogenation/diazotization/cyclization sequence. Angewandte Chemie (International Ed. in English). 52: 4247-50. PMID 23450692 DOI: 10.1002/anie.201300615  1
2013 Vinogradova EV, Park NH, Fors BP, Buchwald SL. Palladium-catalyzed synthesis of N-aryl carbamates. Organic Letters. 15: 1394-7. PMID 23441814 DOI: 10.1021/ol400369n  1
2013 DeAngelis A, Wang DH, Buchwald SL. Mild and rapid Pd-catalyzed cross-coupling with hydrazine in continuous flow: application to the synthesis of functionalized heterocycles. Angewandte Chemie (International Ed. in English). 52: 3434-7. PMID 23404773 DOI: 10.1002/anie.201208544  0.56
2013 Wang X, Buchwald SL. Synthesis of optically pure 2-trifluoromethyl lactic acid by asymmetric hydroformylation. The Journal of Organic Chemistry. 78: 3429-33. PMID 23394066 DOI: 10.1021/jo400115r  1
2013 Yang Y, Oldenhuis NJ, Buchwald SL. Mild and general conditions for negishi cross-coupling enabled by the use of palladacycle precatalysts. Angewandte Chemie (International Ed. in English). 52: 615-9. PMID 23172689 DOI: 10.1002/anie.201207750  1
2012 Spokoyny AM, Lewis CD, Teverovskiy G, Buchwald SL. Extremely Electron-Rich, Boron-Functionalized, Icosahedral Carborane-Based Phosphinoboranes. Organometallics. 31: 8478-8481. PMID 23667288 DOI: 10.1021/om301116x  1
2012 Hoshiya N, Buchwald SL. An Improved Synthesis of BrettPhos and RockPhos-Type Biarylphosphine Ligands. Advanced Synthesis & Catalysis. 354: 2031-2037. PMID 23539491 DOI: 10.1002/adsc.201200398  0.36
2012 Milner PJ, Maimone TJ, Su M, Chen J, Müller P, Buchwald SL. Investigating the dearomative rearrangement of biaryl phosphine-ligated Pd(II) complexes. Journal of the American Chemical Society. 134: 19922-34. PMID 23153301 DOI: 10.1021/ja310351e  1
2012 Tsvelikhovsky D, Buchwald SL. Correction to Synthesis of Heterocycles via Pd-Ligand Controlled Cyclization of 2-Chloro-N-(2-vinyl)aniline: Preparation of Carbazoles, Indoles, Dibenzazepines, and Acridines. Journal of the American Chemical Society. 134: 16917. PMID 23009568 DOI: 10.1021/ja3066094  0.8
2012 Ueda S, Buchwald SL. Catalyst-controlled chemoselective arylation of 2-aminobenzimidazoles. Angewandte Chemie (International Ed. in English). 51: 10364-7. PMID 22969040 DOI: 10.1002/anie.201204710  0.56
2012 Oberli MA, Buchwald SL. A general method for Suzuki-Miyaura coupling reactions using lithium triisopropyl borates. Organic Letters. 14: 4606-9. PMID 22894743 DOI: 10.1021/ol302063g  0.36
2012 Cheung CW, Buchwald SL. Room temperature copper(II)-catalyzed oxidative cyclization of enamides to 2,5-disubstituted oxazoles via vinylic C-H functionalization. The Journal of Organic Chemistry. 77: 7526-37. PMID 22838632 DOI: 10.1021/jo301332s  0.72
2012 Chernyak N, Buchwald SL. Continuous-flow synthesis of monoarylated acetaldehydes using aryldiazonium salts. Journal of the American Chemical Society. 134: 12466-9. PMID 22812501 DOI: 10.1021/ja305660a  0.92
2012 Zhu R, Buchwald SL. Copper-catalyzed oxytrifluoromethylation of unactivated alkenes. Journal of the American Chemical Society. 134: 12462-5. PMID 22804336 DOI: 10.1021/ja305840g  1
2012 McGowan MA, McAvoy CZ, Buchwald SL. Palladium-catalyzed N-monoarylation of amidines and a one-pot synthesis of quinazoline derivatives. Organic Letters. 14: 3800-3. PMID 22765354 DOI: 10.1021/ol301700y  0.6
2012 Vinogradova EV, Fors BP, Buchwald SL. Palladium-catalyzed cross-coupling of aryl chlorides and triflates with sodium cyanate: a practical synthesis of unsymmetrical ureas. Journal of the American Chemical Society. 134: 11132-5. PMID 22716197 DOI: 10.1021/ja305212v  1
2012 Shu W, Buchwald SL. Enantioselective β-arylation of ketones enabled by lithiation/borylation/1,4-addition sequence under flow conditions. Angewandte Chemie (International Ed. in English). 51: 5355-8. PMID 22511537 DOI: 10.1002/anie.201202221  0.8
2012 Su M, Buchwald SL. A bulky biaryl phosphine ligand allows for palladium-catalyzed amidation of five-membered heterocycles as electrophiles. Angewandte Chemie (International Ed. in English). 51: 4710-3. PMID 22473747 DOI: 10.1002/anie.201201244  1
2012 McGowan MA, Henderson JL, Buchwald SL. Palladium-catalyzed N-arylation of 2-aminothiazoles. Organic Letters. 14: 1432-5. PMID 22394197 DOI: 10.1021/ol300178j  0.6
2012 Parsons AT, Senecal TD, Buchwald SL. Iron(II)-catalyzed trifluoromethylation of potassium vinyltrifluoroborates. Angewandte Chemie (International Ed. in English). 51: 2947-50. PMID 22328162 DOI: 10.1002/anie.201108267  1
2012 Ueda S, Ali S, Fors BP, Buchwald SL. Me3(OMe)tBuXPhos: a surrogate ligand for Me4tBuXPhos in palladium-catalyzed C-N and C-O bond-forming reactions. The Journal of Organic Chemistry. 77: 2543-7. PMID 22313416 DOI: 10.1021/jo202537e  1
2012 Zhu R, Buchwald SL. Combined oxypalladation/C-H functionalization: palladium(II)-catalyzed intramolecular oxidative oxyarylation of hydroxyalkenes. Angewandte Chemie (International Ed. in English). 51: 1926-9. PMID 22237989 DOI: 10.1002/anie.201108129  1
2012 Salvi L, Davis NR, Ali SZ, Buchwald SL. A new biarylphosphine ligand for the Pd-catalyzed synthesis of diaryl ethers under mild conditions. Organic Letters. 14: 170-3. PMID 22182186 DOI: 10.1021/ol202955h  0.88
2012 Ueda S, Su M, Buchwald SL. Completely N1-selective palladium-catalyzed arylation of unsymmetric imidazoles: application to the synthesis of nilotinib. Journal of the American Chemical Society. 134: 700-6. PMID 22126442 DOI: 10.1021/ja2102373  1
2012 Pellegatti L, Buchwald SL. Continuous-flow preparation and use of β-chloro enals using the Vilsmeier reagent Organic Process Research and Development. 16: 1442-1448. DOI: 10.1021/op300168z  1
2011 Surry DS, Buchwald SL. Dialkylbiaryl Phosphines in Pd-Catalyzed Amination: A User's Guide. Chemical Science. 2: 27-50. PMID 22432049 DOI: 10.1039/C0SC00331J  1
2011 Maiti D, Fors BP, Henderson JL, Nakamura Y, Buchwald SL. Palladium-Catalyzed Coupling of Functionalized Primary and Secondary Amines with Aryl and Heteroaryl Halides: Two Ligands Suffice in Most Cases. Chemical Science. 2: 57-68. PMID 22384311 DOI: 10.1039/C0SC00330A  1
2011 Parsons AT, Buchwald SL. Organic chemistry: A radical approach to diversity. Nature. 480: 184-5. PMID 22158236 DOI: 10.1038/480184a  1
2011 Cho EJ, Buchwald SL. The palladium-catalyzed trifluoromethylation of vinyl sulfonates. Organic Letters. 13: 6552-5. PMID 22111687 DOI: 10.1021/ol202885w  0.68
2011 Wang X, Buchwald SL. Rh-catalyzed asymmetric hydroformylation of functionalized 1,1-disubstituted olefins. Journal of the American Chemical Society. 133: 19080-3. PMID 22035143 DOI: 10.1021/ja2092689  1
2011 Maimone TJ, Milner PJ, Kinzel T, Zhang Y, Takase MK, Buchwald SL. Evidence for in situ catalyst modification during the Pd-catalyzed conversion of aryl triflates to aryl fluorides. Journal of the American Chemical Society. 133: 18106-9. PMID 21999801 DOI: 10.1021/ja208461k  1
2011 Shu W, Pellegatti L, Oberli MA, Buchwald SL. Continuous-flow synthesis of biaryls enabled by multistep solid-handling in a lithiation/borylation/Suzuki-Miyaura cross-coupling sequence. Angewandte Chemie (International Ed. in English). 50: 10665-9. PMID 21932237 DOI: 10.1002/anie.201105223  0.8
2011 Parsons AT, Buchwald SL. Copper-catalyzed trifluoromethylation of unactivated olefins. Angewandte Chemie (International Ed. in English). 50: 9120-3. PMID 21919144 DOI: 10.1002/anie.201104053  1
2011 Wu X, Fors BP, Buchwald SL. A single phosphine ligand allows palladium-catalyzed intermolecular C-O bond formation with secondary and primary alcohols. Angewandte Chemie (International Ed. in English). 50: 9943-7. PMID 21913292 DOI: 10.1002/anie.201104361  1
2011 Pan J, Wang X, Zhang Y, Buchwald SL. An improved palladium-catalyzed conversion of aryl and vinyl triflates to bromides and chlorides. Organic Letters. 13: 4974-6. PMID 21863838 DOI: 10.1021/ol202098h  1
2011 Ueda S, Su M, Buchwald SL. Highly N2-selective palladium-catalyzed arylation of 1,2,3-triazoles. Angewandte Chemie (International Ed. in English). 50: 8944-7. PMID 21853510 DOI: 10.1002/anie.201103882  1
2011 Tsvelikhovsky D, Buchwald SL. Concise palladium-catalyzed synthesis of dibenzodiazepines and structural analogues. Journal of the American Chemical Society. 133: 14228-31. PMID 21838278 DOI: 10.1021/ja206229y  0.8
2011 Noël T, Maimone TJ, Buchwald SL. Accelerating palladium-catalyzed C-F bond formation: use of a microflow packed-bed reactor. Angewandte Chemie (International Ed. in English). 50: 8900-3. PMID 21837710 DOI: 10.1002/anie.201104652  1
2011 Noël T, Buchwald SL. Cross-coupling in flow. Chemical Society Reviews. 40: 5010-29. PMID 21826351 DOI: 10.1039/c1cs15075h  0.88
2011 Pan J, Su M, Buchwald SL. Palladium(0)-catalyzed intermolecular amination of unactivated C(sp³)-H bonds. Angewandte Chemie (International Ed. in English). 50: 8647-51. PMID 21812078 DOI: 10.1002/anie.201102880  1
2011 Teverovskiy G, Surry DS, Buchwald SL. Pd-catalyzed synthesis of Ar-SCF3 compounds under mild conditions. Angewandte Chemie (International Ed. in English). 50: 7312-4. PMID 21692157 DOI: 10.1002/anie.201102543  1
2011 Li P, Buchwald SL. Continuous-flow synthesis of 3,3-disubstituted oxindoles by a palladium-catalyzed α-arylation/alkylation sequence. Angewandte Chemie (International Ed. in English). 50: 6396-400. PMID 21656623 DOI: 10.1002/anie.201102401  0.92
2011 Rousseaux S, García-Fortanet J, Del Aguila Sanchez MA, Buchwald SL. Palladium(0)-catalyzed arylative dearomatization of phenols. Journal of the American Chemical Society. 133: 9282-5. PMID 21612204 DOI: 10.1021/ja203644q  0.68
2011 Breitler S, Oldenhuis NJ, Fors BP, Buchwald SL. Synthesis of unsymmetrical diarylureas via Pd-catalyzed C-N cross-coupling reactions. Organic Letters. 13: 3262-5. PMID 21604792 DOI: 10.1021/ol201210t  1
2011 Noël T, Kuhn S, Musacchio AJ, Jensen KF, Buchwald SL. Suzuki-Miyaura cross-coupling reactions in flow: multistep synthesis enabled by a microfluidic extraction. Angewandte Chemie (International Ed. in English). 50: 5943-6. PMID 21591040 DOI: 10.1002/anie.201101480  0.88
2011 Senecal TD, Parsons AT, Buchwald SL. Room temperature aryl trifluoromethylation via copper-mediated oxidative cross-coupling. The Journal of Organic Chemistry. 76: 1174-6. PMID 21235259 DOI: 10.1021/jo1023377  1
2011 Shu W, Buchwald SL. Use of precatalysts greatly facilitate palladium-catalyzed alkynylations in batch and continuous-flow conditions Chemical Science. 2: 2321-2325. DOI: 10.1039/c1sc00409c  1
2011 Noël T, Naber JR, Hartman RL, Mcmullen JP, Jensen KF, Buchwald SL. Palladium-catalyzed amination reactions in flow: Overcoming the challenges of clogging via acoustic irradiation Chemical Science. 2: 287-290. DOI: 10.1039/c0sc00524j  1
2010 Naber JR, Fors BP, Wu X, Gunn J, Buchwald SL. STILLE CROSS-COUPLING REACTIONS OF ARYL MESYLATES AND TOSYLATES USING A BIARYLPHOSPHINE BASED CATALYST SYSTEM. Heterocycles. 80: 1215-1226. PMID 23596345 DOI: 10.3987/COM-09-S(S)105  1
2010 Surry DS, Buchwald SL. Diamine Ligands in Copper-Catalyzed Reactions. Chemical Science. 1: 13-31. PMID 22384310 DOI: 10.1039/C0SC00107D  1
2010 Naber JR, Buchwald SL. Packed-bed reactors for continuous-flow C-N cross-coupling. Angewandte Chemie (International Ed. in English). 49: 9469-74. PMID 21038337 DOI: 10.1002/anie.201004425  0.84
2010 Fors BP, Buchwald SL. A multiligand based Pd catalyst for C-N cross-coupling reactions. Journal of the American Chemical Society. 132: 15914-7. PMID 20979367 DOI: 10.1021/ja108074t  1
2010 Henderson JL, Buchwald SL. Efficient Pd-catalyzed amination reactions for heterocycle functionalization. Organic Letters. 12: 4442-5. PMID 20860403 DOI: 10.1021/ol101929v  0.36
2010 Henderson JL, McDermott SM, Buchwald SL. Palladium-catalyzed amination of unprotected halo-7-azaindoles. Organic Letters. 12: 4438-41. PMID 20860393 DOI: 10.1021/ol101928m  0.36
2010 Tsvelikhovsky D, Buchwald SL. Synthesis of heterocycles via Pd-ligand controlled cyclization of 2-chloro-N-(2-vinyl)aniline: preparation of carbazoles, indoles, dibenzazepines, and acridines. Journal of the American Chemical Society. 132: 14048-51. PMID 20858012 DOI: 10.1021/ja107511g  0.8
2010 Kinzel T, Zhang Y, Buchwald SL. A new palladium precatalyst allows for the fast Suzuki-Miyaura coupling reactions of unstable polyfluorophenyl and 2-heteroaryl boronic acids. Journal of the American Chemical Society. 132: 14073-5. PMID 20858009 DOI: 10.1021/ja1073799  1
2010 Shen X, Hyde AM, Buchwald SL. Palladium-catalyzed conversion of aryl and vinyl triflates to bromides and chlorides. Journal of the American Chemical Society. 132: 14076-8. PMID 20857936 DOI: 10.1021/ja107481a  1
2010 McMullen JP, Stone MT, Buchwald SL, Jensen KF. An integrated microreactor system for self-optimization of a Heck reaction: from micro- to mesoscale flow systems. Angewandte Chemie (International Ed. in English). 49: 7076-80. PMID 20726027 DOI: 10.1002/anie.201002590  0.52
2010 Shen X, Jones GO, Watson DA, Bhayana B, Buchwald SL. Enantioselective synthesis of axially chiral biaryls by the Pd-catalyzed Suzuki-Miyaura reaction: substrate scope and quantum mechanical investigations. Journal of the American Chemical Society. 132: 11278-87. PMID 20698695 DOI: 10.1021/ja104297g  1
2010 Maimone TJ, Buchwald SL. Pd-catalyzed O-arylation of ethyl acetohydroximate: synthesis of O-arylhydroxylamines and substituted benzofurans. Journal of the American Chemical Society. 132: 9990-1. PMID 20604520 DOI: 10.1021/ja1044874  1
2010 Cho EJ, Senecal TD, Kinzel T, Zhang Y, Watson DA, Buchwald SL. The palladium-catalyzed trifluoromethylation of aryl chlorides. Science (New York, N.Y.). 328: 1679-81. PMID 20576888 DOI: 10.1126/science.1190524  1
2010 Dooleweerdt K, Fors BP, Buchwald SL. Pd-catalyzed cross-coupling reactions of amides and aryl mesylates. Organic Letters. 12: 2350-3. PMID 20420379 DOI: 10.1021/ol100720x  1
2010 Jones GO, Liu P, Houk KN, Buchwald SL. Computational explorations of mechanisms and ligand-directed selectivities of copper-catalyzed Ullmann-type reactions. Journal of the American Chemical Society. 132: 6205-13. PMID 20387898 DOI: 10.1021/ja100739h  0.84
2010 Maiti D, Buchwald SL. Cu-catalyzed arylation of phenols: synthesis of sterically hindered and heteroaryl diaryl ethers. The Journal of Organic Chemistry. 75: 1791-4. PMID 20141182 DOI: 10.1021/jo9026935  1
2010 Hartman RL, Naber JR, Buchwald SL, Jensen KF. Multistep microchemical synthesis enabled by microfluidic distillation. Angewandte Chemie (International Ed. in English). 49: 899-903. PMID 20025004 DOI: 10.1002/anie.200904634  0.84
2010 Shen X, Buchwald SL. Rhodium-catalyzed asymmetric intramolecular hydroamination of unactivated alkenes. Angewandte Chemie (International Ed. in English). 49: 564-7. PMID 20014268 DOI: 10.1002/anie.200905402  0.84
2010 Hartman RL, Naber JR, Zaborenko N, Buchwald SL, Jensen KF. Overcoming the challenges of solid bridging and constriction during Pd-catalyzed C-N bond formation in microreactors Organic Process Research and Development. 14: 1347-1357. DOI: 10.1021/op100154d  1
2010 Fors BP, Buchwald SL. Commentary on "a new, efficient and recyclable lanthanum(III) oxide-catalyzed C-N cross-coupling" by S. Narayana Murthy, B. Madhav, V. Prakash Reddy, and Y. V. D. Nageswar, Adv. Synth. Catal. 2010, 352, 3241-3245 Advanced Synthesis and Catalysis. 352: 3119-3120. DOI: 10.1002/adsc.201000905  1
2009 Lee BK, Biscoe MR, Buchwald SL. Simple, Efficient Protocols for the Pd-Catalyzed Cross-Coupling Reaction of Aryl Chlorides and Dimethylamine. Tetrahedron Letters. 50: 3672-3674. PMID 21818164 DOI: 10.1016/j.tetlet.2009.03.137  1
2009 Fors BP, Dooleweerdt K, Zeng Q, Buchwald SL. An Efficient System For the Pd-Catalyzed Cross-Coupling of Amides and Aryl Chlorides. Tetrahedron. 65: 6576-6583. PMID 20740063 DOI: 10.1016/j.tet.2009.04.096  1
2009 Maiti D, Buchwald SL. Orthogonal Cu- and Pd-based catalyst systems for the O- and N-arylation of aminophenols. Journal of the American Chemical Society. 131: 17423-9. PMID 19899753 DOI: 10.1021/ja9081815  1
2009 Hicks JD, Hyde AM, Cuezva AM, Buchwald SL. Pd-catalyzed N-arylation of secondary acyclic amides: catalyst development, scope, and computational study. Journal of the American Chemical Society. 131: 16720-34. PMID 19886610 DOI: 10.1021/ja9044357  1
2009 Fors BP, Buchwald SL. Pd-catalyzed conversion of aryl chlorides, triflates, and nonaflates to nitroaromatics. Journal of the American Chemical Society. 131: 12898-9. PMID 19737014 DOI: 10.1021/ja905768k  1
2009 Watson DA, Su M, Teverovskiy G, Zhang Y, García-Fortanet J, Kinzel T, Buchwald SL. Formation of ArF from LPdAr(F): catalytic conversion of aryl triflates to aryl fluorides. Science (New York, N.Y.). 325: 1661-4. PMID 19679769 DOI: 10.1126/science.1178239  1
2009 Bhayana B, Fors BP, Buchwald SL. A versatile catalyst system for Suzuki-Miyaura cross-coupling reactions of C(sp(2))-tosylates and mesylates. Organic Letters. 11: 3954-7. PMID 19663467 DOI: 10.1021/ol9015892  1
2009 Taylor AM, Altman RA, Buchwald SL. Palladium-catalyzed enantioselective alpha-arylation and alpha-vinylation of oxindoles facilitated by an axially chiral P-stereogenic ligand. Journal of the American Chemical Society. 131: 9900-1. PMID 19580273 DOI: 10.1021/ja903880q  0.96
2009 Hyde AM, Buchwald SL. Synthesis of 5,5-disubstituted butenolides based on a Pd-catalyzed gamma-arylation strategy. Organic Letters. 11: 2663-6. PMID 19449882 DOI: 10.1021/ol9007102  1
2009 Han C, Buchwald SL. Negishi coupling of secondary alkylzinc halides with aryl bromides and chlorides. Journal of the American Chemical Society. 131: 7532-3. PMID 19441851 DOI: 10.1021/ja902046m  1
2009 García-Fortanet J, Kessler F, Buchwald SL. Palladium-catalyzed asymmetric dearomatization of naphthalene derivatives. Journal of the American Chemical Society. 131: 6676-7. PMID 19388652 DOI: 10.1021/ja9025193  0.68
2009 Fors BP, Davis NR, Buchwald SL. An efficient process for pd-catalyzed C-N cross-coupling reactions of aryl iodides: insight into controlling factors. Journal of the American Chemical Society. 131: 5766-8. PMID 19348431 DOI: 10.1021/ja901414u  1
2009 Biscoe MR, Buchwald SL. Selective monoarylation of acetate esters and aryl methyl ketones using aryl chlorides. Organic Letters. 11: 1773-5. PMID 19296693 DOI: 10.1021/ol900295u  1
2009 Strieter ER, Bhayana B, Buchwald SL. Mechanistic studies on the copper-catalyzed N-arylation of amides. Journal of the American Chemical Society. 131: 78-88. PMID 19072233 DOI: 10.1021/ja0781893  0.96
2008 Martín R, Buchwald SL. An improved protocol for the Pd-catalyzed alpha-arylation of aldehydes with aryl halides. Organic Letters. 10: 4561-4. PMID 18808127 DOI: 10.1021/ol8017775  0.32
2008 Fors BP, Watson DA, Biscoe MR, Buchwald SL. A highly active catalyst for Pd-catalyzed amination reactions: cross-coupling reactions using aryl mesylates and the highly selective monoarylation of primary amines using aryl chlorides. Journal of the American Chemical Society. 130: 13552-4. PMID 18798626 DOI: 10.1021/ja8055358  1
2008 García-Fortanet J, Buchwald SL. Asymmetric palladium-catalyzed intramolecular alpha-arylation of aldehydes. Angewandte Chemie (International Ed. in English). 47: 8108-11. PMID 18792905 DOI: 10.1002/anie.200803809  0.68
2008 Tsang WC, Munday RH, Brasche G, Zheng N, Buchwald SL. Palladium-catalyzed method for the synthesis of carbazoles via tandem C-H functionalization and C-N bond formation. The Journal of Organic Chemistry. 73: 7603-10. PMID 18761437 DOI: 10.1021/jo801273q  1
2008 Watson DA, Fan X, Buchwald SL. Carbonylation of aryl chlorides with oxygen nucleophiles at atmospheric pressure. Preparation of phenyl esters as acyl transfer agents and the direct preparation of alkyl esters and carboxylic acids. The Journal of Organic Chemistry. 73: 7096-101. PMID 18720992 DOI: 10.1021/jo800907e  1
2008 Martinelli JR, Watson DA, Freckmann DM, Barder TE, Buchwald SL. Palladium-catalyzed carbonylation reactions of aryl bromides at atmospheric pressure: a general system based on Xantphos. The Journal of Organic Chemistry. 73: 7102-7. PMID 18720970 DOI: 10.1021/jo801279r  1
2008 Surry DS, Buchwald SL. Biaryl phosphane ligands in palladium-catalyzed amination. Angewandte Chemie (International Ed. in English). 47: 6338-61. PMID 18663711 DOI: 10.1002/anie.200800497  1
2008 Fors BP, Krattiger P, Strieter E, Buchwald SL. Water-mediated catalyst preactivation: an efficient protocol for C-N cross-coupling reactions. Organic Letters. 10: 3505-8. PMID 18620415 DOI: 10.1021/ol801285g  1
2008 Altman RA, Hyde AM, Huang X, Buchwald SL. Orthogonal Pd- and Cu-based catalyst systems for C- and N-arylation of oxindoles. Journal of the American Chemical Society. 130: 9613-20. PMID 18588302 DOI: 10.1021/ja803179s  1
2008 Billingsley KL, Buchwald SL. An improved system for the palladium-catalyzed borylation of aryl halides with pinacol borane. The Journal of Organic Chemistry. 73: 5589-91. PMID 18576604 DOI: 10.1021/jo800727s  1
2008 Altman RA, Anderson KW, Buchwald SL. Pyrrole-2-carboxylic acid as a ligand for the Cu-catalyzed reactions of primary anilines with aryl halides. The Journal of Organic Chemistry. 73: 5167-9. PMID 18543973 DOI: 10.1021/jo8008676  1
2008 Minatti A, Buchwald SL. Synthesis of indolines via a domino Cu-catalyzed amidation/cyclization reaction. Organic Letters. 10: 2721-4. PMID 18522394 DOI: 10.1021/ol8008792  0.72
2008 Billingsley KL, Buchwald SL. A general and efficient method for the Suzuki-Miyaura coupling of 2-pyridyl nucleophiles. Angewandte Chemie (International Ed. in English). 47: 4695-8. PMID 18491343 DOI: 10.1002/anie.200801465  1
2008 Wang H, Duennwald ML, Roberts BE, Rozeboom LM, Zhang YL, Steele AD, Krishnan R, Su LJ, Griffin D, Mukhopadhyay S, Hennessy EJ, Weigele P, Blanchard BJ, King J, Deniz AA, ... Buchwald SL, et al. Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs. Proceedings of the National Academy of Sciences of the United States of America. 105: 7159-64. PMID 18480256 DOI: 10.1073/pnas.0801934105  0.84
2008 Brasche G, García-Fortanet J, Buchwald SL. Twofold C-H functionalization: palladium-catalyzed ortho arylation of anilides. Organic Letters. 10: 2207-10. PMID 18465866 DOI: 10.1021/ol800619c  0.68
2008 Biscoe MR, Fors BP, Buchwald SL. A new class of easily activated palladium precatalysts for facile C-N cross-coupling reactions and the low temperature oxidative addition of aryl chlorides. Journal of the American Chemical Society. 130: 6686-7. PMID 18447360 DOI: 10.1021/ja801137k  1
2008 Munday RH, Martinelli JR, Buchwald SL. Palladium-catalyzed carbonylation of aryl tosylates and mesylates. Journal of the American Chemical Society. 130: 2754-5. PMID 18257577 DOI: 10.1021/ja711449e  0.88
2008 Brasche G, Buchwald SL. C-H functionalization/C-N bond formation: copper-catalyzed synthesis of benzimidazoles from amidines. Angewandte Chemie (International Ed. in English). 47: 1932-4. PMID 18228236 DOI: 10.1002/anie.200705420  0.68
2008 Altman RA, Shafir A, Choi A, Lichtor PA, Buchwald SL. An improved Cu-based catalyst system for the reactions of alcohols with aryl halides. The Journal of Organic Chemistry. 73: 284-6. PMID 18044928 DOI: 10.1021/jo702024p  0.96
2008 Hyde AM, Buchwald SL. Palladium-catalyzed gamma-arylation of beta,gamma-unsaturated ketones: application to a one-pot synthesis of tricyclic indolines. Angewandte Chemie (International Ed. in English). 47: 177-80. PMID 18033712 DOI: 10.1002/anie.200704529  1
2008 Naber JR, Buchwald SL. Palladium-catalyzed Stille cross-coupling reaction of aryl chlorides using a pre-milled palladium acetate and XPhos catalyst system Advanced Synthesis and Catalysis. 350: 957-961. DOI: 10.1002/adsc.200800032  1
2007 Altman RA, Buchwald SL. Pd-catalyzed Suzuki-Miyaura reactions of aryl halides using bulky biarylmonophosphine ligands. Nature Protocols. 2: 3115-21. PMID 18079711 DOI: 10.1038/nprot.2007.411  0.96
2007 Martín R, Cuenca A, Buchwald SL. Sequential copper-catalyzed vinylation/cyclization: an efficient synthesis of functionalized oxazoles. Organic Letters. 9: 5521-4. PMID 18020351 DOI: 10.1021/ol7024718  0.32
2007 Altman RA, Fors BP, Buchwald SL. Pd-catalyzed amination reactions of aryl halides using bulky biarylmonophosphine ligands. Nature Protocols. 2: 2881-7. PMID 18007623 DOI: 10.1038/nprot.2007.414  1
2007 Minatti A, Zheng X, Buchwald SL. Synthesis of chiral 3-substituted indanones via an enantioselective reductive-Heck reaction. The Journal of Organic Chemistry. 72: 9253-8. PMID 17967034 DOI: 10.1021/jo701741y  0.72
2007 Zheng N, Buchwald SL. Copper-catalyzed regiospecific synthesis of N-alkylbenzimidazoles. Organic Letters. 9: 4749-51. PMID 17949007 DOI: 10.1021/ol7020737  1
2007 Altman RA, Buchwald SL. Cu-catalyzed Goldberg and Ullmann reactions of aryl halides using chelating N- and O-based ligands. Nature Protocols. 2: 2474-9. PMID 17947989 DOI: 10.1038/nprot.2007.364  0.96
2007 Ikawa T, Barder TE, Biscoe MR, Buchwald SL. Pd-catalyzed amidation of aryl chlorides using monodentate biaryl phosphine ligands: a kinetic, computational, and synthetic investigation. Journal of the American Chemical Society. 129: 13001-7. PMID 17918833 DOI: 10.1021/ja0717414  1
2007 Martinelli JR, Clark TP, Watson DA, Munday RH, Buchwald SL. Palladium-catalyzed aminocarbonylation of aryl chlorides at atmospheric pressure: the dual role of sodium phenoxide. Angewandte Chemie (International Ed. in English). 46: 8460-3. PMID 17902084 DOI: 10.1002/anie.200702943  1
2007 Jones CP, Anderson KW, Buchwald SL. Sequential Cu-catalyzed amidation-base-mediated camps cyclization: a two-step synthesis of 2-Aryl-4-quinolones from o-halophenones. The Journal of Organic Chemistry. 72: 7968-73. PMID 17850097 DOI: 10.1021/jo701384n  1
2007 Barder TE, Buchwald SL. Insights into amine binding to biaryl phosphine palladium oxidative addition complexes and reductive elimination from biaryl phosphine arylpalladium amido complexes via density functional theory. Journal of the American Chemical Society. 129: 12003-10. PMID 17850080 DOI: 10.1021/ja073747z  1
2007 Martín R, Buchwald SL. A general method for the direct alpha-arylation of aldehydes with aryl bromides and chlorides. Angewandte Chemie (International Ed. in English). 46: 7236-9. PMID 17722128 DOI: 10.1002/anie.200703009  0.32
2007 Zheng N, Anderson KW, Huang X, Nguyen HN, Buchwald SL. A palladium-catalyzed regiospecific synthesis of N-aryl benzimidazoles. Angewandte Chemie (International Ed. in English). 46: 7509-12. PMID 17722125 DOI: 10.1002/anie.200702542  1
2007 McNeill E, Barder TE, Buchwald SL. Palladium-catalyzed silylation of aryl chlorides with hexamethyldisilane. Organic Letters. 9: 3785-8. PMID 17705501 DOI: 10.1021/ol701518f  1
2007 Biscoe MR, Barder TE, Buchwald SL. Electronic effects on the selectivity of pd-catalyzed C-N bond-forming reactions using biarylphosphine ligands: the competitive roles of amine binding and acidity. Angewandte Chemie (International Ed. in English). 46: 7232-5. PMID 17680583 DOI: 10.1002/anie.200702122  1
2007 Surry DS, Buchwald SL. Selective palladium-catalyzed arylation of ammonia: synthesis of anilines as well as symmetrical and unsymmetrical di- and triarylamines. Journal of the American Chemical Society. 129: 10354-5. PMID 17672469 DOI: 10.1021/ja074681a  1
2007 Martín R, Larsen CH, Cuenca A, Buchwald SL. Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles. Organic Letters. 9: 3379-82. PMID 17655316 DOI: 10.1021/ol7014225  1
2007 Altman RA, Koval ED, Buchwald SL. Copper-catalyzed N-arylation of imidazoles and benzimidazoles. The Journal of Organic Chemistry. 72: 6190-9. PMID 17625886 DOI: 10.1021/jo070807a  0.96
2007 Billingsley KL, Barder TE, Buchwald SL. Palladium-catalyzed borylation of aryl chlorides: scope, applications, and computational studies. Angewandte Chemie (International Ed. in English). 46: 5359-63. PMID 17562550 DOI: 10.1002/anie.200701551  1
2007 Murphy ER, Martinelli JR, Zaborenko N, Buchwald SL, Jensen KF. Accelerating reactions with microreactors at elevated temperatures and pressures: profiling aminocarbonylation reactions. Angewandte Chemie (International Ed. in English). 46: 1734-7. PMID 17397088 DOI: 10.1002/anie.200604175  0.88
2007 Barder TE, Buchwald SL. Rationale behind the resistance of dialkylbiaryl phosphines toward oxidation by molecular oxygen. Journal of the American Chemical Society. 129: 5096-101. PMID 17388595 DOI: 10.1021/ja0683180  1
2007 Shafir A, Lichtor PA, Buchwald SL. N- versus O-arylation of aminoalcohols: orthogonal selectivity in copper-based catalysts. Journal of the American Chemical Society. 129: 3490-1. PMID 17341083 DOI: 10.1021/ja068926f  0.48
2007 Altman RA, Buchwald SL. Cu-catalyzed N- and O-arylation of 2-, 3-, and 4-hydroxypyridines and hydroxyquinolines. Organic Letters. 9: 643-6. PMID 17286371 DOI: 10.1021/ol062904g  0.96
2007 Barder TE, Buchwald SL. Benchtop monitoring of reaction progress via visual recognition with a handheld UV lamp: in situ monitoring of boronic acids in the Suzuki-Miyaura reaction. Organic Letters. 9: 137-9. PMID 17192104 DOI: 10.1021/ol062802q  1
2007 Barder TE, Biscoe MR, Buchwald SL. Structural insights into active catalyst structures and oxidative addition to (biaryl)phosphine - palladium complexes via density functional theory and experimental studies Organometallics. 26: 2183-2192. DOI: 10.1021/om0701017  1
2006 Martinelli JR, Freckmann DM, Buchwald SL. Convenient method for the preparation of Weinreb amides via Pd-catalyzed aminocarbonylation of aryl bromides at atmospheric pressure. Organic Letters. 8: 4843-6. PMID 17020317 DOI: 10.1021/ol061902t  0.88
2006 Martín R, Rodríguez Rivero M, Buchwald SL. Domino cu-catalyzed C--N coupling/hydroamidation: a highly efficient synthesis of nitrogen heterocycles. Angewandte Chemie (International Ed. in English). 45: 7079-82. PMID 17009380 DOI: 10.1002/anie.200602917  0.32
2006 Anderson KW, Tundel RE, Ikawa T, Altman RA, Buchwald SL. Monodentate phosphines provide highly active catalysts for Pd-catalyzed C-N bond-forming reactions of heteroaromatic halides/amines and (H)N-heterocycles. Angewandte Chemie (International Ed. in English). 45: 6523-7. PMID 16955526 DOI: 10.1002/anie.200601612  1
2006 Anderson KW, Ikawa T, Tundel RE, Buchwald SL. The selective reaction of aryl halides with KOH: synthesis of phenols, aromatic ethers, and benzofurans. Journal of the American Chemical Society. 128: 10694-5. PMID 16910660 DOI: 10.1021/ja0639719  1
2006 Shafir A, Buchwald SL. Highly selective room-temperature copper-catalyzed C-N coupling reactions. Journal of the American Chemical Society. 128: 8742-3. PMID 16819863 DOI: 10.1021/ja063063b  0.48
2006 Altman RA, Buchwald SL. 4,7-Dimethoxy-1,10-phenanthroline: an excellent ligand for the Cu-catalyzed N-arylation of imidazoles. Organic Letters. 8: 2779-82. PMID 16774255 DOI: 10.1021/ol0608505  0.96
2006 Burgos CH, Barder TE, Huang X, Buchwald SL. Significantly improved method for the pd-catalyzed coupling of phenols with aryl halides: understanding ligand effects. Angewandte Chemie (International Ed. in English). 45: 4321-6. PMID 16733839 DOI: 10.1002/anie.200601253  1
2006 Billingsley KL, Anderson KW, Buchwald SL. A highly active catalyst for Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds. Angewandte Chemie (International Ed. in English). 45: 3484-8. PMID 16639772 DOI: 10.1002/anie.200600493  1
2006 Shekhar S, Ryberg P, Hartwig JF, Mathew JS, Blackmond DG, Strieter ER, Buchwald SL. Reevaluation of the mechanism of the amination of aryl halides catalyzed by BINAP-ligated palladium complexes. Journal of the American Chemical Society. 128: 3584-91. PMID 16536531 DOI: 10.1021/ja045533c  0.96
2006 Tundel RE, Anderson KW, Buchwald SL. Expedited palladium-catalyzed amination of aryl nonaflates through the use of microwave-irradiation and soluble organic amine bases. The Journal of Organic Chemistry. 71: 430-3. PMID 16388678 DOI: 10.1021/jo052131u  1
2006 Strieter ER, Buchwald SL. Evidence for the formation and structure of palladacycles during Pd-catalyzed C-N bond formation with catalysts derived from bulky monophosphinobiaryl ligands. Angewandte Chemie (International Ed. in English). 45: 925-8. PMID 16381052 DOI: 10.1002/anie.200502927  0.96
2006 Larsen CH, Anderson KW, Tundel RE, Buchwald SL. Palladium-catalyzed Heck alkynylation of benzyl chlorides Synlett. 2941-2946. DOI: 10.1055/s-2006-949625  1
2005 Tsang WC, Zheng N, Buchwald SL. Combined C-H functionalization/C-N bond formation route to carbazoles. Journal of the American Chemical Society. 127: 14560-1. PMID 16231894 DOI: 10.1021/ja055353i  1
2005 Rainka MP, Milne JE, Buchwald SL. Dynamic kinetic resolution of alpha,beta-unsaturated lactones through asymmetric copper-catalyzed conjugate reduction: application to the total synthesis of eupomatilone-3. Angewandte Chemie (International Ed. in English). 44: 6177-80. PMID 16130153 DOI: 10.1002/anie.200501890  0.92
2005 Hennessy EJ, Buchwald SL. Synthesis of 4,5-dianilinophthalimide and related analogues for potential treatment of Alzheimer's disease via palladium-catalyzed amination. The Journal of Organic Chemistry. 70: 7371-5. PMID 16122261 DOI: 10.1021/jo051096o  0.8
2005 Anderson KW, Buchwald SL. General catalysts for the Suzuki-Miyaura and Sonogashira coupling reactions of aryl chlorides and for the coupling of challenging substrate combinations in water. Angewandte Chemie (International Ed. in English). 44: 6173-7. PMID 16097019 DOI: 10.1002/anie.200502017  1
2005 Vorogushin AV, Huang X, Buchwald SL. Use of tunable ligands allows for intermolecular Pd-catalyzed C--O bond formation. Journal of the American Chemical Society. 127: 8146-9. PMID 15926842 DOI: 10.1021/ja050471r  1
2005 Barder TE, Walker SD, Martinelli JR, Buchwald SL. Catalysts for Suzuki-Miyaura coupling processes: scope and studies of the effect of ligand structure. Journal of the American Chemical Society. 127: 4685-96. PMID 15796535 DOI: 10.1021/ja042491j  1
2005 Strieter ER, Blackmond DG, Buchwald SL. The role of chelating diamine ligands in the goldberg reaction: a kinetic study on the copper-catalyzed amidation of aryl iodides. Journal of the American Chemical Society. 127: 4120-1. PMID 15783164 DOI: 10.1021/ja050120c  0.96
2004 Chae J, Yun J, Buchwald SL. One-pot sequential Cu-catalyzed reduction and Pd-catalyzed arylation of silyl enol ethers. Organic Letters. 6: 4809-12. PMID 15606072 DOI: 10.1021/ol048313c  1
2004 Milne JE, Buchwald SL. An extremely active catalyst for the Negishi cross-coupling reaction. Journal of the American Chemical Society. 126: 13028-32. PMID 15469301 DOI: 10.1021/ja0474493  0.52
2004 Antilla JC, Baskin JM, Barder TE, Buchwald SL. Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles. The Journal of Organic Chemistry. 69: 5578-87. PMID 15307726 DOI: 10.1021/jo049658b  1
2004 Barder TE, Buchwald SL. Efficient catalyst for the Suzuki-Miyaura coupling of potassium aryl trifluoroborates with aryl chlorides. Organic Letters. 6: 2649-52. PMID 15281735 DOI: 10.1021/ol0491686  1
2004 Chae J, Buchwald SL. Palladium-catalyzed regioselective hydrodebromination of dibromoindoles: application to the enantioselective synthesis of indolodioxane U86192A. The Journal of Organic Chemistry. 69: 3336-9. PMID 15132539 DOI: 10.1021/jo035819k  1
2004 Rainka MP, Aye Y, Buchwald SL. Copper-catalyzed asymmetric conjugate reduction as a route to novel beta-azaheterocyclic acid derivatives. Proceedings of the National Academy of Sciences of the United States of America. 101: 5821-3. PMID 15067136 DOI: 10.1073/pnas.0307764101  0.92
2004 Walker SD, Barder TE, Martinelli JR, Buchwald SL. A rationally designed universal catalyst for Suzuki-Miyaura coupling processes. Angewandte Chemie (International Ed. in English). 43: 1871-6. PMID 15054800 DOI: 10.1002/anie.200353615  1
2004 Klapars A, Parris S, Anderson KW, Buchwald SL. Synthesis of medium ring nitrogen heterocycles via a tandem copper-catalyzed C-N bond formation-ring-expansion process. Journal of the American Chemical Society. 126: 3529-33. PMID 15025480 DOI: 10.1021/ja038565t  1
2003 Gelman D, Buchwald SL. Efficient palladium-catalyzed coupling of aryl chlorides and tosylates with terminal alkynes: use of a copper cocatalyst inhibits the reaction. Angewandte Chemie (International Ed. in English). 42: 5993-6. PMID 14679552 DOI: 10.1002/anie.200353015  0.96
2003 Anderson KW, Mendez-Perez M, Priego J, Buchwald SL. Palladium-catalyzed amination of aryl nonaflates. The Journal of Organic Chemistry. 68: 9563-73. PMID 14656080 DOI: 10.1021/jo034962a  1
2003 Strieter ER, Blackmond DG, Buchwald SL. Insights into the origin of high activity and stability of catalysts derived from bulky, electron-rich monophosphinobiaryl ligands in the Pd-catalyzed C-N bond formation. Journal of the American Chemical Society. 125: 13978-80. PMID 14611232 DOI: 10.1021/ja037932y  0.96
2003 Hennessy EJ, Buchwald SL. Synthesis of substituted oxindoles from alpha-chloroacetanilides via palladium-catalyzed C[bond]H functionalization. Journal of the American Chemical Society. 125: 12084-5. PMID 14518981 DOI: 10.1021/ja037546g  0.8
2003 Jiang L, Job GE, Klapars A, Buchwald SL. Copper-catalyzed coupling of amides and carbamates with vinyl halides. Organic Letters. 5: 3667-9. PMID 14507200 DOI: 10.1021/ol035355c  0.96
2003 Nguyen HN, Huang X, Buchwald SL. The first general palladium catalyst for the Suzuki-Miyaura and carbonyl enolate coupling of aryl arenesulfonates. Journal of the American Chemical Society. 125: 11818-9. PMID 14505394 DOI: 10.1021/ja036947t  1
2003 Jurkauskas V, Sadighi JP, Buchwald SL. Conjugate reduction of alpha,beta-unsaturated carbonyl compounds catalyzed by a copper carbene complex. Organic Letters. 5: 2417-20. PMID 12841744 DOI: 10.1021/ol034560p  1
2003 Zim D, Buchwald SL. An air and thermally stable one- component catalyst for the amination of aryl chlorides. Organic Letters. 5: 2413-5. PMID 12841743 DOI: 10.1021/ol034561h  0.64
2003 Gelman D, Jiang L, Buchwald SL. Copper-catalyzed C-P bond construction via direct coupling of secondary phosphines and phosphites with aryl and vinyl halides. Organic Letters. 5: 2315-8. PMID 12816437 DOI: 10.1021/ol0346640  0.96
2003 Huang X, Anderson KW, Zim D, Jiang L, Klapars A, Buchwald SL. Expanding Pd-catalyzed C-N bond-forming processes: the first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions. Journal of the American Chemical Society. 125: 6653-5. PMID 12769573 DOI: 10.1021/ja035483w  1
2003 Kwong FY, Buchwald SL. Mild and efficient copper-catalyzed amination of aryl bromides with primary alkylamines. Organic Letters. 5: 793-6. PMID 12633073 DOI: 10.1021/ol0273396  0.96
2003 Zanon J, Klapars A, Buchwald SL. Copper-catalyzed domino halide exchange-cyanation of aryl bromides. Journal of the American Chemical Society. 125: 2890-1. PMID 12617652 DOI: 10.1021/ja0299708  0.96
2002 Rutherford JL, Rainka MP, Buchwald SL. An annulative approach to highly substituted indoles: unusual effect of phenolic additives on the success of the arylation of ketone enolates. Journal of the American Chemical Society. 124: 15168-9. PMID 12487580  0.92
2002 Klapars A, Buchwald SL. Copper-catalyzed halogen exchange in aryl halides: an aromatic Finkelstein reaction. Journal of the American Chemical Society. 124: 14844-5. PMID 12475315  0.96
2002 Singh UK, Strieter ER, Blackmond DG, Buchwald SL. Mechanistic insights into the Pd(BINAP)-catalyzed amination of aryl bromides: kinetic studies under synthetically relevant conditions. Journal of the American Chemical Society. 124: 14104-14. PMID 12440909  0.96
2002 Job GE, Buchwald SL. Copper-catalyzed arylation of beta-amino alcohols. Organic Letters. 4: 3703-6. PMID 12375923  0.44
2002 Kwong FY, Buchwald SL. A general, efficient, and inexpensive catalyst system for the coupling of aryl iodides and thiols. Organic Letters. 4: 3517-20. PMID 12323058  0.96
2002 Antilla JC, Klapars A, Buchwald SL. The copper-catalyzed N-arylation of indoles. Journal of the American Chemical Society. 124: 11684-8. PMID 12296734  1
2002 Harris MC, Huang X, Buchwald SL. Improved functional group compatibility in the palladium-catalyzed synthesis of aryl amines. Organic Letters. 4: 2885-8. PMID 12182580  1
2002 Klapars A, Huang X, Buchwald SL. A general and efficient copper catalyst for the amidation of aryl halides. Journal of the American Chemical Society. 124: 7421-8. PMID 12071751  1
2002 Yin J, Buchwald SL. Pd-catalyzed intermolecular amidation of aryl halides: the discovery that xantphos can be trans-chelating in a palladium complex. Journal of the American Chemical Society. 124: 6043-8. PMID 12022838  1
2002 Sturla SJ, Buchwald SL. Cobalt-phosphite-catalyzed asymmetric Pauson-Khand reaction. The Journal of Organic Chemistry. 67: 3398-403. PMID 12003551  0.96
2002 Jurkauskas V, Buchwald SL. Dynamic kinetic resolution via asymmetric conjugate reduction: enantio- and diastereoselective synthesis of 2,4-dialkyl cyclopentanones. Journal of the American Chemical Society. 124: 2892-3. PMID 11902878  1
2002 Hamada T, Buchwald SL. P-chirogenic binaphthyl-substituted monophosphines: synthesis and use in enolate vinylation/arylation reactions. Organic Letters. 4: 999-1001. PMID 11893206  0.4
2002 Wolter M, Nordmann G, Job GE, Buchwald SL. Copper-catalyzed coupling of aryl iodides with aliphatic alcohols. Organic Letters. 4: 973-6. PMID 11893199  0.44
2002 Kwong FY, Klapars A, Buchwald SL. Copper-catalyzed coupling of alkylamines and aryl iodides: an efficient system even in an air atmosphere. Organic Letters. 4: 581-4. PMID 11843596  0.96
2002 Hamada T, Chieffi A, Ahman J, Buchwald SL. An improved catalyst for the asymmetric arylation of ketone enolates. Journal of the American Chemical Society. 124: 1261-8. PMID 11841295  0.56
2002 Yin J, Rainka MP, Zhang XX, Buchwald SL. A highly active Suzuki catalyst for the synthesis of sterically hindered biaryls: novel ligand coordination. Journal of the American Chemical Society. 124: 1162-3. PMID 11841272  1
2002 Hennessy EJ, Buchwald SL. A general and mild copper-catalyzed arylation of diethyl malonate. Organic Letters. 4: 269-72. PMID 11796067  0.8
2001 Kuwabe SI, Torraca KE, Buchwald SL. Palladium-catalyzed intramolecular C-O bond formation. Journal of the American Chemical Society. 123: 12202-6. PMID 11734019 DOI: 10.1021/ja012046d  1
2001 Wolter M, Klapars A, Buchwald SL. Synthesis of N-aryl hydrazides by copper-catalyzed coupling of hydrazides with aryl iodides. Organic Letters. 3: 3803-5. PMID 11700143 DOI: 10.1021/ol0168216  0.96
2001 Torraca KE, Huang X, Parrish CA, Buchwald SL. An efficient intermolecular palladium-catalyzed synthesis of aryl ethers. Journal of the American Chemical Society. 123: 10770-1. PMID 11674023 DOI: 10.1021/ja016863p  1
2001 Huang X, Buchwald SL. New ammonia equivalents for the Pd-catalyzed amination of aryl halides. Organic Letters. 3: 3417-9. PMID 11594848 DOI: 10.1021/ol0166808  1
2001 Klapars A, Antilla JC, Huang X, Buchwald SL. A general and efficient copper catalyst for the amidation of aryl halides and the N-arylation of nitrogen heterocycles. Journal of the American Chemical Society. 123: 7727-9. PMID 11481007 DOI: 10.1021/ja016226z  1
2001 Antilla JC, Buchwald SL. Copper-catalyzed coupling of arylboronic acids and amines. Organic Letters. 3: 2077-9. PMID 11418053 DOI: 10.1021/ol0160396  1
2001 Chieffi A, Kamikawa K, Ahman J, Fox JM, Buchwald SL. Catalytic asymmetric vinylation of ketone enolates. Organic Letters. 3: 1897-900. PMID 11405739 DOI: 10.1021/ol0159470  1
2001 Parrish CA, Buchwald SL. Use of polymer-supported dialkylphosphinobiphenyl ligands for palladium-catalyzed amination and Suzuki reactions. The Journal of Organic Chemistry. 66: 3820-7. PMID 11375003 DOI: 10.1021/jo010025w  1
2001 Yun J, Buchwald SL. One-pot synthesis of enantiomerically enriched 2,3-disubstituted cyclopentanones via copper-catalyzed 1,4-reduction and alkylation. Organic Letters. 3: 1129-31. PMID 11348176  1
2001 Parrish CA, Buchwald SL. Palladium-catalyzed formation of aryl tert-butyl ethers from unactivated aryl halides. The Journal of Organic Chemistry. 66: 2498-500. PMID 11281795 DOI: 10.1021/jo001426z  1
2000 Zhang XX, Buchwald SL. Efficient synthesis of N-aryl-aza-crown ethers via palladium-catalyzed amination The Journal of Organic Chemistry. 65: 8027-31. PMID 11073613  0.96
2000 Tomori H, Fox JM, Buchwald SL. An improved synthesis of functionalized biphenyl-based phosphine ligands. The Journal of Organic Chemistry. 65: 5334-41. PMID 10993363 DOI: 10.1021/jo000691h  1
2000 Harris MC, Buchwald SL. One-pot synthesis of unsymmetrical triarylamines from aniline precursors. The Journal of Organic Chemistry. 65: 5327-33. PMID 10993362  1
2000 Hundertmark T, Littke AF, Buchwald SL, Fu GC. Pd(PhCN)(2)Cl(2)/P(t-Bu)(3): a versatile catalyst for Sonogashira reactions of aryl bromides at room temperature. Organic Letters. 2: 1729-31. PMID 10880212  0.68
2000 Yun J, Buchwald SL. Kinetic resolution and isomerization of 2,5-disubstituted pyrrolines. Chirality. 12: 476-8. PMID 10824173 DOI: 10.1002/(SICI)1520-636X(2000)12:5/6<476::AID-CHIR31>3.0.CO;2-B  1
2000 Old DW, Harris MC, Buchwald SL. Efficient palladium-catalyzed N-arylation of indoles. Organic Letters. 2: 1403-6. PMID 10814458  1
2000 Hansen MC, Buchwald SL. A method for the asymmetric hydrosilylation of N-aryl imines. Organic Letters. 2: 713-5. PMID 10814417  1
2000 Wolfe JP, Tomori H, Sadighi JP, Yin J, Buchwald SL. Simple, efficient catalyst system for the palladium-catalyzed amination of aryl chlorides, bromides, and triflates. The Journal of Organic Chemistry. 65: 1158-74. PMID 10814067 DOI: 10.1021/jo991699y  1
2000 Wolfe JP, Buchwald SL. Scope and limitations of the Pd/BINAP-catalyzed amination of aryl bromides. The Journal of Organic Chemistry. 65: 1144-57. PMID 10814066 DOI: 10.1021/jo9916986  1
2000 Yun J, Buchwald SL. Efficient kinetic resolution in the asymmetric hydrosilylation of imines of 3-substituted indanones and 4-substituted tetralones. The Journal of Organic Chemistry. 65: 767-74. PMID 10814009 DOI: 10.1021/jo991328h  1
2000 Yin J, Buchwald SL. Palladium-catalyzed intermolecular coupling of aryl halides and amides. Organic Letters. 2: 1101-4. PMID 10804564  1
1999 Sturla SJ, Buchwald SL. Catalytic Asymmetric Cyclocarbonylation of Nitrogen-Containing Enynes. The Journal of Organic Chemistry. 64: 5547-5550. PMID 11674619  0.96
1999 Yang BH, Buchwald SL. The development of efficient protocols for the palladium-catalyzed cyclization reactions of secondary amides and carbamates. Organic Letters. 1: 35-7. PMID 10822529  0.8
1999 Wolfe JP, Buchwald SL. A Highly Active Catalyst for the Room-Temperature Amination and Suzuki Coupling of Aryl Chlorides. Angewandte Chemie (International Ed. in English). 38: 2413-2416. PMID 10458806 DOI: 10.1002/(SICI)1521-3773(19990816)38:16<2413::AID-ANIE2413>3.0.CO;2-H  1
1998 Reding MT, Buchwald SL. Short Enantioselective Total Syntheses of the Piperidine Alkaloids (S)-Coniine and (2R,6R)-trans-Solenopsin A via Catalytic Asymmetric Imine Hydrosilylation. The Journal of Organic Chemistry. 63: 6344-6347. PMID 11672268  0.84
1997 Verdaguer X, Hansen MC, Berk SC, Buchwald SL. Titanocene-Catalyzed Reduction of Lactones to Lactols. The Journal of Organic Chemistry. 62: 8522-8528. PMID 11671995  0.88
1997 Chin B, Buchwald SL. Improved Procedure for the Preparation of Enantiomerically Pure Ethylenebis(tetrahydroindenyl)zirconium Derivatives. The Journal of Organic Chemistry. 62: 2267-2268. PMID 11671540  1
1996 Wagaw S, Buchwald SL. The Synthesis of Aminopyridines: A Method Employing Palladium-Catalyzed Carbon-Nitrogen Bond Formation. The Journal of Organic Chemistry. 61: 7240-7241. PMID 11667641  0.32
1996 Zhang M, Buchwald SL. A Nickel(0)-Catalyzed Process for the Transformation of Enynes to Bicyclic Cyclopentenones. The Journal of Organic Chemistry. 61: 4498-4499. PMID 11667365  0.96
1996 Hicks FA, Berk SC, Buchwald SL. A Practical Titanium-Catalyzed Synthesis of Bicyclic Cyclopentenones and Allylic Amines. The Journal of Organic Chemistry. 61: 2713-2718. PMID 11667103  0.88
1995 Warner BP, Millar SP, Broene RD, Buchwald SL. Controlled acceleration and inhibition of bergman cyclization by metal chlorides. Science (New York, N.Y.). 269: 814-6. PMID 17778739 DOI: 10.1126/science.269.5225.814  1
1993 Broene RD, Buchwald SL. Zirconocene complexes of unsaturated organic molecules: new vehicles for organic synthesis. Science (New York, N.Y.). 261: 1696-701. PMID 8378769  1
1984 Buchwald SL, Saini MS, Knowles JR, Van Etten RL. Stereochemical course of phospho group transfer by human prostatic acid phosphatase. The Journal of Biological Chemistry. 259: 2208-13. PMID 6698963  1
1982 Buchwald SL, Hansen DE, Hassett A, Knowles JR. Chiral [16O, 17O, 18O]phosphoric monoesters as stereochemical probes of phosphotransferases. Methods in Enzymology. 87: 279-301. PMID 6294451  0.44
1981 Saini MS, Buchwald SL, Van Etten RL, Knowles JR. Stereochemistry of phospho transfer catalyzed by bovine liver acid phosphatase. The Journal of Biological Chemistry. 256: 10453-5. PMID 7287718  1
1977 Cane DE, Buchwald SL. Application of deuterium magnetic resonance to biosynthetic studies. 1. Biosynthesis of ovalicin. Journal of the American Chemical Society. 99: 6132-4. PMID 893881  1
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