Joel M. Gottesfeld, Ph.D. - Publications

1978- Cell and Molecular Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Biochemistry, Molecular Biology

136 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Rodden LN, Chutake YK, Gilliam K, Lam C, Soragni E, Hauser L, Gilliam M, Wiley G, Anderson MP, Gottesfeld JM, Lynch DR, Bidichandani SI. Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia. Human Molecular Genetics. PMID 33432325 DOI: 10.1093/hmg/ddaa267  0.307
2019 Gottesfeld JM. Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31317428 DOI: 10.1007/S13311-019-00764-X  0.395
2019 Gottesfeld JM. Milestones in transcription and chromatin published in the . The Journal of Biological Chemistry. 294: 1652-1660. PMID 30710013 DOI: 10.1074/Jbc.Tm118.004162  0.429
2018 Lai JI, Nachun D, Petrosyan L, Throesch B, Campau E, Gao F, Baldwin KK, Coppola G, Gottesfeld JM, Soragni E. Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures. The Journal of Biological Chemistry. PMID 30552117 DOI: 10.1074/Jbc.Ra118.006515  0.744
2018 Gottesfeld JM, Carey MF. Introduction to Thematic Minireview Series: Chromatin and Transcription. The Journal of Biological Chemistry. PMID 30068547 DOI: 10.1074/Jbc.Tm118.004544  0.426
2018 Soragni E, Petrosyan L, Rinkoski TA, Wieben ED, Baratz KH, Fautsch MP, Gottesfeld JM. Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy. Investigative Ophthalmology & Visual Science. 59: 1888-1896. PMID 29677349 DOI: 10.1167/Iovs.17-23265  0.339
2017 Lai JI, Leman LJ, Ku S, Vickers CJ, Olsen CA, Montero A, Ghadiri MR, Gottesfeld JM. Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. Bioorganic & Medicinal Chemistry Letters. PMID 28648462 DOI: 10.1016/J.Bmcl.2017.06.027  0.764
2016 Soragni E, Gottesfeld JM. Translating HDAC inhibitors in Friedrich's ataxia. Expert Opinion On Orphan Drugs. 4: 961-970. PMID 28392990 DOI: 10.1080/21678707.2016.1215910  0.399
2016 Jia H, Wang Y, Morris CD, Jacques V, Gottesfeld JM, Rusche JR, Thomas EA. The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice. Plos One. 11: e0152498. PMID 27031333 DOI: 10.1371/Journal.Pone.0152498  0.362
2016 Soragni E, Gottesfeld JM. Translating HDAC inhibitors in Friedreich’s ataxia Expert Opinion On Orphan Drugs. 4: 961-970. DOI: 10.1080/21678707.2016.1215910  0.302
2015 Soragni E, Chou CJ, Rusche JR, Gottesfeld JM. Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia. Frontiers in Neurology. 6: 44. PMID 25798128 DOI: 10.3389/Fneur.2015.00044  0.413
2015 Du J, Aleff RA, Soragni E, Kalari K, Nie J, Tang X, Davila J, Kocher JP, Patel SV, Gottesfeld JM, Baratz KH, Wieben ED. RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy. The Journal of Biological Chemistry. 290: 5979-90. PMID 25593321 DOI: 10.1074/Jbc.M114.621607  0.331
2014 Soragni E, Miao W, Iudicello M, Jacoby D, De Mercanti S, Clerico M, Longo F, Piga A, Ku S, Campau E, Du J, Penalver P, Rai M, Madara JC, Nazor K, ... ... Gottesfeld JM, et al. Epigenetic therapy for Friedreich ataxia. Annals of Neurology. 76: 489-508. PMID 25159818 DOI: 10.1002/Ana.24260  0.764
2014 Shan B, Xu C, Zhang Y, Xu T, Gottesfeld JM, Yates JR. Quantitative proteomic analysis identifies targets and pathways of a 2-aminobenzamide HDAC inhibitor in Friedreich's ataxia patient iPSC-derived neural stem cells. Journal of Proteome Research. 13: 4558-66. PMID 24933366 DOI: 10.1021/Pr500514R  0.363
2014 Rao M, Gottesfeld JM. Introduction to thematic minireview series: Development of human therapeutics based on induced pluripotent stem Cell (iPSC) technology Journal of Biological Chemistry. 289: 4553-4554. PMID 24362035 DOI: 10.1074/Jbc.R113.543652  0.313
2013 Du J, Campau E, Soragni E, Jespersen C, Gottesfeld JM. Length-dependent CTG·CAG triplet-repeat expansion in myotonic dystrophy patient-derived induced pluripotent stem cells. Human Molecular Genetics. 22: 5276-87. PMID 23933738 DOI: 10.1093/Hmg/Ddt386  0.377
2013 Gottesfeld JM, Rusche JR, Pandolfo M. Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia. Journal of Neurochemistry. 126: 147-54. PMID 23859350 DOI: 10.1111/Jnc.12302  0.476
2012 Denu JM, Gottesfeld JM. Minireview series on sirtuins: from biochemistry to health and disease. The Journal of Biological Chemistry. 287: 42417-8. PMID 23086946 DOI: 10.1074/Jbc.R112.428862  0.321
2012 Du J, Campau E, Soragni E, Ku S, Puckett JW, Dervan PB, Gottesfeld JM. Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells. The Journal of Biological Chemistry. 287: 29861-72. PMID 22798143 DOI: 10.1074/Jbc.M112.391961  0.788
2012 Soragni E, Xu C, Plasterer HL, Jacques V, Rusche JR, Gottesfeld JM. Rationale for the development of 2-aminobenzamide histone deacetylase inhibitors as therapeutics for Friedreich ataxia. Journal of Child Neurology. 27: 1164-73. PMID 22764181 DOI: 10.1177/0883073812448533  0.362
2012 Jespersen C, Soragni E, James Chou C, Arora PS, Dervan PB, Gottesfeld JM. Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells. Bioorganic & Medicinal Chemistry Letters. 22: 4068-71. PMID 22607671 DOI: 10.1016/J.Bmcl.2012.04.090  0.666
2012 Jia H, Pallos J, Jacques V, Lau A, Tang B, Cooper A, Syed A, Purcell J, Chen Y, Sharma S, Sangrey GR, Darnell SB, Plasterer H, Sadri-Vakili G, Gottesfeld JM, et al. Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. Neurobiology of Disease. 46: 351-61. PMID 22590724 DOI: 10.1016/J.Nbd.2012.01.016  0.373
2012 Polak U, Hirsch C, Ku S, Gottesfeld J, Dent SY, Napierala M. Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts. Journal of Visualized Experiments : Jove. PMID 22370855 DOI: 10.3791/3416  0.764
2012 Soragni E, Ku S, Gottesfeld JM. Epigenetics: Analysis of Histone Post-Translational Modifications by Chromatin Immunoprecipitation Human Stem Cell Manual. 313-323. DOI: 10.1016/B978-0-12-385473-5.00019-9  0.781
2011 Xu C, Soragni E, Jacques V, Rusche JR, Gottesfeld JM. Improved Histone Deacetylase Inhibitors as Therapeutics for the Neurodegenerative Disease Friedreich's Ataxia: A New Synthetic Route. Pharmaceuticals (Basel, Switzerland). 4: 1578-1590. PMID 27721337 DOI: 10.3390/Ph4121578  0.356
2011 Coppola G, Burnett R, Perlman S, Versano R, Gao F, Plasterer H, Rai M, Saccá F, Filla A, Lynch DR, Rusche JR, Gottesfeld JM, Pandolfo M, Geschwind DH. A gene expression phenotype in lymphocytes from Friedreich ataxia patients. Annals of Neurology. 70: 790-804. PMID 22162061 DOI: 10.1002/Ana.22526  0.712
2011 Soragni E, Xu C, Cooper A, Plasterer HL, Rusche JR, Gottesfeld JM. Evaluation of histone deacetylase inhibitors as therapeutics for neurodegenerative diseases. Methods in Molecular Biology (Clifton, N.J.). 793: 495-508. PMID 21913121 DOI: 10.1007/978-1-61779-328-8_32  0.378
2011 Gottesfeld JM. Introduction to the thematic minireview series on epigenetics. The Journal of Biological Chemistry. 286: 18345-6. PMID 21454488 DOI: 10.1074/Jbc.R111.243527  0.452
2011 Sandi C, Pinto RM, Al-Mahdawi S, Ezzatizadeh V, Barnes G, Jones S, Rusche JR, Gottesfeld JM, Pook MA. Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model. Neurobiology of Disease. 42: 496-505. PMID 21397024 DOI: 10.1016/J.Nbd.2011.02.016  0.379
2011 Laurent LC, Ulitsky I, Slavin I, Tran H, Schork A, Morey R, Lynch C, Harness JV, Lee S, Barrero MJ, Ku S, Martynova M, Semechkin R, Galat V, Gottesfeld J, et al. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell. 8: 106-18. PMID 21211785 DOI: 10.1016/J.Stem.2010.12.003  0.771
2010 Ku S, Soragni E, Campau E, Thomas EA, Altun G, Laurent LC, Loring JF, Napierala M, Gottesfeld JM. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability. Cell Stem Cell. 7: 631-7. PMID 21040903 DOI: 10.1016/J.Stem.2010.09.014  0.806
2010 Rai M, Soragni E, Chou CJ, Barnes G, Jones S, Rusche JR, Gottesfeld JM, Pandolfo M. Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model. Plos One. 5: e8825. PMID 20098685 DOI: 10.1371/Journal.Pone.0008825  0.408
2010 Hutt DM, Herman D, Rodrigues AP, Noel S, Pilewski JM, Matteson J, Hoch B, Kellner W, Kelly JW, Schmidt A, Thomas PJ, Matsumura Y, Skach WR, Gentzsch M, Riordan JR, ... ... Gottesfeld JM, et al. Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nature Chemical Biology. 6: 25-33. PMID 19966789 DOI: 10.1038/Nchembio.275  0.307
2010 Minoshima M, Chou JC, Lefebvre S, Bando T, Shinohara K, Gottesfeld JM, Sugiyama H. Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes. Bioorganic & Medicinal Chemistry. 18: 168-74. PMID 19962902 DOI: 10.1016/J.Bmc.2009.11.005  0.459
2009 Gottesfeld JM, Pandolfo M. Development of histone deacetylase inhibitors as therapeutics for neurological disease. Future Neurology. 4: 775-784. PMID 20177429 DOI: 10.2217/Fnl.09.55  0.402
2009 Xu C, Soragni E, Chou CJ, Herman D, Plasterer HL, Rusche JR, Gottesfeld JM. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chemistry & Biology. 16: 980-9. PMID 19778726 DOI: 10.1016/J.Chembiol.2009.07.010  0.388
2008 Chou CJ, O'Hare T, Lefebvre S, Alvarez D, Tyner JW, Eide CA, Druker BJ, Gottesfeld JM. Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate. Plos One. 3: e3593. PMID 18974832 DOI: 10.1371/Journal.Pone.0003593  0.308
2008 Chou CJ, Herman D, Gottesfeld JM. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. The Journal of Biological Chemistry. 283: 35402-9. PMID 18953021 DOI: 10.1074/Jbc.M807045200  0.345
2008 Thomas EA, Coppola G, Desplats PA, Tang B, Soragni E, Burnett R, Gao F, Fitzgerald KM, Borok JF, Herman D, Geschwind DH, Gottesfeld JM. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 15564-9. PMID 18829438 DOI: 10.1073/Pnas.0804249105  0.691
2008 Soragni E, Herman D, Dent SY, Gottesfeld JM, Wells RD, Napierala M. Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia. Nucleic Acids Research. 36: 6056-65. PMID 18820300 DOI: 10.1093/Nar/Gkn604  0.429
2008 Minoshima M, Chou J, Lefebvre S, Bando T, Shinohara K, Gottesfeld JM, Sugiyama H. Targeting specific gene by alkylating pyrrole-imidazole polyamides. Nucleic Acids Symposium Series (2004). 363-4. PMID 18776404 DOI: 10.1093/nass/nrn183  0.325
2008 Rai M, Soragni E, Jenssen K, Burnett R, Herman D, Coppola G, Geschwind DH, Gottesfeld JM, Pandolfo M. HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model. Plos One. 3: e1958. PMID 18463734 DOI: 10.1371/Journal.Pone.0001958  0.711
2008 Chou CJ, Farkas ME, Tsai SM, Alvarez D, Dervan PB, Gottesfeld JM. Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia. Molecular Cancer Therapeutics. 7: 769-78. PMID 18413791 DOI: 10.1158/1535-7163.Mct-08-0130  0.627
2008 Rai M, Soragni E, Jenssen K, Burnett R, Herman D, Coppola G, Geschwind DH, Gottesfeld JM, Pandolfo M. Effects of HDAC inhibitor 106 on frataxin mRNA and protein levels and on histone acetylation in KIKI mice. Plos One. DOI: 10.1371/Journal.Pone.0001958.G003  0.31
2007 Gottesfeld JM. Small molecules affecting transcription in Friedreich ataxia. Pharmacology & Therapeutics. 116: 236-48. PMID 17826840 DOI: 10.1016/J.Pharmthera.2007.06.014  0.374
2007 Tsai SM, Farkas ME, Chou CJ, Gottesfeld JM, Dervan PB. Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates. Nucleic Acids Research. 35: 307-16. PMID 17170006 DOI: 10.1093/Nar/Gkl1025  0.592
2007 Herman D, Jenssen K, Burnett R, Soragni E, Perlman SL, Gottesfeld JM. Erratum: Corrigendum: Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia Nature Chemical Biology. 3: 432-432. DOI: 10.1038/Nchembio0707-432  0.337
2006 Herman D, Jenssen K, Burnett R, Soragni E, Perlman SL, Gottesfeld JM. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nature Chemical Biology. 2: 551-8. PMID 16921367 DOI: 10.1038/Nchembio815  0.702
2006 Alvarez D, Chou CJ, Latella L, Zeitlin SG, Ku S, Puri PL, Dervan PB, Gottesfeld JM. A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate. Cell Cycle (Georgetown, Tex.). 5: 1537-48. PMID 16861886 DOI: 10.4161/Cc.5.14.2913  0.777
2006 Burnett R, Melander C, Puckett JW, Son LS, Wells RD, Dervan PB, Gottesfeld JM. DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia. Proceedings of the National Academy of Sciences of the United States of America. 103: 11497-502. PMID 16857735 DOI: 10.1073/Pnas.0604939103  0.837
2006 Trzupek JD, Gottesfeld JM, Boger DL. Alkylation of duplex DNA in nucleosome core particles by duocarmycin SA and yatakemycin. Nature Chemical Biology. 2: 79-82. PMID 16415862 DOI: 10.1038/Nchembio761  0.434
2006 Lee BM, Xu J, Clarkson BK, Martinez-Yamout MA, Dyson HJ, Case DA, Gottesfeld JM, Wright PE. Induced fit and "lock and key" recognition of 5S RNA by zinc fingers of transcription factor IIIA. Journal of Molecular Biology. 357: 275-91. PMID 16405997 DOI: 10.1016/J.Jmb.2005.12.010  0.379
2006 Raï M, Gottesfeld J, Dervan P, Pandolfo M. T.P.2 09 Overcoming the transcription defect in Friedreich ataxia with designed DNA ligands Neuromuscular Disorders. 16: 705-706. DOI: 10.1016/J.Nmd.2006.05.201  0.361
2006 Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting Cancer Proliferation by Small-Molecule Gene Regulation (DOI:10.1016/j.chembiol.2004.09.004) Chemistry and Biology. 13: 339. DOI: 10.1016/J.Chembiol.2006.02.006  0.717
2005 Gearhart MD, Dickinson L, Ehley J, Melander C, Dervan PB, Wright PE, Gottesfeld JM. Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides. Biochemistry. 44: 4196-203. PMID 15766247 DOI: 10.1021/Bi047872O  0.756
2005 Beltran AC, Dawson PE, Gottesfeld JM. Role of DNA sequence in the binding specificity of synthetic basic-helix-loop-helix domains. Chembiochem : a European Journal of Chemical Biology. 6: 104-13. PMID 15593070 DOI: 10.1002/Cbic.200400184  0.793
2005 Edayathumangalam RS, Weyermann P, Dervan PB, Gottesfeld JM, Luger K. Nucleosomes in solution exist as a mixture of twist-defect states. Journal of Molecular Biology. 345: 103-14. PMID 15567414 DOI: 10.1016/J.Jmb.2004.10.012  0.662
2004 Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting cancer proliferation by small-molecule gene regulation. Chemistry & Biology. 11: 1583-94. PMID 15556009 DOI: 10.1016/J.Chembiol.2004.09.004  0.801
2004 Melander C, Burnett R, Gottesfeld JM. Regulation of gene expression with pyrrole-imidazole polyamides. Journal of Biotechnology. 112: 195-220. PMID 15288953 DOI: 10.1016/J.Jbiotec.2004.03.018  0.818
2004 Edayathumangalam RS, Weyermann P, Gottesfeld JM, Dervan PB, Luger K. Molecular recognition of the nucleosomal "supergroove". Proceedings of the National Academy of Sciences of the United States of America. 101: 6864-9. PMID 15100411 DOI: 10.1073/Pnas.0401743101  0.703
2003 Dudouet B, Burnett R, Dickinson LA, Wood MR, Melander C, Belitsky JM, Edelson B, Wurtz N, Briehn C, Dervan PB, Gottesfeld JM. Accessibility of nuclear chromatin by DNA binding polyamides. Chemistry & Biology. 10: 859-67. PMID 14522056 DOI: 10.1016/J.Chembiol.2003.09.001  0.838
2003 Gottesfeld JM, Barbas CF. RNA as a transcriptional activator. Chemistry & Biology. 10: 584-5. PMID 12890529 DOI: 10.1016/S1074-5521(03)00153-4  0.363
2003 Suto RK, Edayathumangalam RS, White CL, Melander C, Gottesfeld JM, Dervan PB, Luger K. Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. Journal of Molecular Biology. 326: 371-80. PMID 12559907 DOI: 10.1016/S0022-2836(02)01407-9  0.752
2002 Gottesfeld JM, Belitsky JM, Melander C, Dervan PB, Luger K. Blocking transcription through a nucleosome with synthetic DNA ligands. Journal of Molecular Biology. 321: 249-63. PMID 12144782 DOI: 10.1016/S0022-2836(02)00598-3  0.788
2002 Ehley JA, Melander C, Herman D, Baird EE, Ferguson HA, Goodrich JA, Dervan PB, Gottesfeld JM. Promoter scanning for transcription inhibition with DNA-binding polyamides. Molecular and Cellular Biology. 22: 1723-33. PMID 11865052 DOI: 10.1128/Mcb.22.6.1723-1733.2002  0.789
2002 Luger K, Suto RK, Edayathumangalam R, Gottesfeld J, Melander C, Dervan PB. Structural basis for site-specific recognition of nucleosomal DNA Acta Crystallographica Section a Foundations of Crystallography. 58: c35-c35. DOI: 10.1107/S0108767302086506  0.628
2001 Gottesfeld JM, Luger K. Energetics and affinity of the histone octamer for defined DNA sequences. Biochemistry. 40: 10927-33. PMID 11551187 DOI: 10.1021/Bi0109966  0.455
2001 Gottesfeld JM, Melander C, Suto RK, Raviol H, Luger K, Dervan PB. Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides. Journal of Molecular Biology. 309: 615-29. PMID 11397084 DOI: 10.1006/Jmbi.2001.4694  0.774
2001 Turner JM, Gottesfeld JM. Regulation of gene expression with synthetic DNA-binding ligands Chemtracts. 14: 563-572.  0.354
2000 Gottesfeld JM, Turner JM, Dervan PB. Chemical approaches to control gene expression. Gene Expression. 9: 77-91. PMID 11097426 DOI: 10.3727/000000001783992696  0.685
2000 Winston RL, Ehley JA, Baird EE, Dervan PB, Gottesfeld JM. Asymmetric DNA binding by a homodimeric bHLH protein. Biochemistry. 39: 9092-8. PMID 10924102 DOI: 10.1021/Bi000947D  0.813
2000 Winston RL, Gottesfeld JM. Rapid identification of key amino-acid-DNA contacts through combinatorial peptide synthesis. Chemistry & Biology. 7: 245-51. PMID 10780928 DOI: 10.1016/S1074-5521(00)00099-5  0.799
1999 Dickinson LA, Trauger JW, Baird EE, Ghazal P, Dervan PB, Gottesfeld JM. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides. Biochemistry. 38: 10801-7. PMID 10451376 DOI: 10.1021/Bi9912847  0.71
1999 Neely LS, Lee BM, Xu J, Wright PE, Gottesfeld JM. Identification of a minimal domain of 5 S ribosomal RNA sufficient for high affinity interactions with the RNA-specific zinc fingers of transcription factor IIIA. Journal of Molecular Biology. 291: 549-60. PMID 10448036 DOI: 10.1006/Jmbi.1999.2985  0.388
1999 Winston RL, Millar DP, Gottesfeld JM, Kent SB. Characterization of the DNA binding properties of the bHLH domain of Deadpan to single and tandem sites. Biochemistry. 38: 5138-46. PMID 10213619 DOI: 10.1021/Bi982856A  0.804
1999 Dickinson LA, Trauger JW, Baird EE, Dervan PB, Graves BJ, Gottesfeld JM. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. The Journal of Biological Chemistry. 274: 12765-73. PMID 10212261 DOI: 10.1074/jbc.274.18.12765  0.66
1999 McBryant SJ, Baird EE, Trauger JW, Dervan PB, Gottesfeld JM. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand. Journal of Molecular Biology. 286: 973-81. PMID 10047474 DOI: 10.1006/Jmbi.1999.2539  0.728
1998 Dickinson LA, Gulizia RJ, Trauger JW, Baird EE, Mosier DE, Gottesfeld JM, Dervan PB. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proceedings of the National Academy of Sciences of the United States of America. 95: 12890-5. PMID 9789010 DOI: 10.1073/Pnas.95.22.12890  0.727
1998 Long JJ, Leresche A, Kriwacki RW, Gottesfeld JM. Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis. Molecular and Cellular Biology. 18: 1467-76. PMID 9488463 DOI: 10.1128/Mcb.18.3.1467  0.384
1997 McBryant SJ, Gottesfeld JM. Differential kinetics of transcription complex assembly distinguish oocyte and somatic 5S RNA genes of Xenopus. Gene Expression. 6: 387-99. PMID 9495319  0.368
1997 Neely L, Trauger JW, Baird EE, Dervan PB, Gottesfeld JM. Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex. Journal of Molecular Biology. 274: 439-45. PMID 9417925 DOI: 10.1006/Jmbi.1997.1411  0.717
1997 Wuttke DS, Foster MP, Case DA, Gottesfeld JM, Wright PE. Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity. Journal of Molecular Biology. 273: 183-206. PMID 9367756 DOI: 10.1006/Jmbi.1997.1291  0.448
1997 Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE. Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA. Nature Structural Biology. 4: 605-8. PMID 9253405 DOI: 10.1038/Nsb0897-605  0.438
1997 Gottesfeld JM, Forbes DJ. Mitotic repression of the transcriptional machinery Trends in Biochemical Sciences. 22: 197-202. PMID 9204705 DOI: 10.1016/S0968-0004(97)01045-1  0.437
1997 Gottesfeld JM, Neely L, Trauger JW, Baird EE, Dervan PB. Regulation of gene expression by small molecules. Nature. 387: 202-5. PMID 9144294 DOI: 10.1038/387202A0  0.738
1996 Leresche A, Wolf VJ, Gottesfeld JM. Repression of RNA polymerase II and III transcription during M phase of the cell cycle. Experimental Cell Research. 229: 282-8. PMID 8986611 DOI: 10.1006/Excr.1996.0373  0.418
1996 Brown ML, Schroth GP, Gottesfeld JM, Bazett-Jones DP. Protein and DNA requirements for the transcription factor IIIA-induced distortion of the 5 S rRNA gene promoter Journal of Molecular Biology. 262: 600-614. PMID 8876641 DOI: 10.1006/Jmbi.1996.0539  0.526
1996 McBryant SJ, Meier E, Leresche A, Sharp SJ, Wolf VJ, Gottesfeld JM. TATA-box DNA binding activity and subunit composition for RNA polymerase III transcription factor IIIB from Xenopus laevis. Molecular and Cellular Biology. 16: 4639-47. PMID 8756620 DOI: 10.1128/Mcb.16.9.4639  0.505
1996 McBryant SJ, Gedulin B, Clemens KR, Wright PE, Gottesfeld JM. Assessment of major and minor groove DNA interactions by the zinc fingers of Xenopus transcription factor IIIA. Nucleic Acids Research. 24: 2567-74. PMID 8692697 DOI: 10.1093/Nar/24.13.2567  0.483
1996 Gottesfeld JM, Johnson DL, Nyborg JK. Transcriptional activation of RNA polymerase III-dependent genes by the human T-cell leukemia virus type 1 Tax protein Molecular and Cellular Biology. 16: 1777-1785. PMID 8657153 DOI: 10.1128/Mcb.16.4.1777  0.446
1995 McBryant SJ, Kassavetis GA, Gottesfeld JM. Repression of vertebrate RNA polymerase III transcription by DNA binding proteins located upstream from the transcription start site. Journal of Molecular Biology. 250: 315-26. PMID 7608977 DOI: 10.1006/Jmbi.1995.0379  0.48
1994 Gottesfeld JM, Wolf VJ, Dang T, Forbes DJ, Hartl P. Mitotic repression of RNA polymerase III transcription in vitro mediated by phosphorylation of a TFIIIB component. Science (New York, N.Y.). 263: 81-4. PMID 8272869 DOI: 10.1126/Science.8272869  0.38
1994 Wolf VJ, Dang T, Hartl P, Gottesfeld JM. Role of maturation-promoting factor (p34cdc2-cyclin B) in differential expression of the Xenopus oocyte and somatic-type 5S RNA genes. Molecular and Cellular Biology. 14: 4704-11. PMID 8007972 DOI: 10.1128/Mcb.14.7.4704  0.454
1994 Clemens KR, Zhang P, Liao X, McBryant SJ, Wright PE, Gottesfeld JM. Relative contributions of the zinc fingers of transcription factor IIIA to the energetics of DNA binding. Journal of Molecular Biology. 244: 23-35. PMID 7966319 DOI: 10.1006/Jmbi.1994.1701  0.496
1993 Clemens KR, Wolf V, McBryant SJ, Zhang P, Liao X, Wright PE, Gottesfeld JM. Molecular basis for specific recognition of both RNA and DNA by a zinc finger protein. Science (New York, N.Y.). 260: 530-3. PMID 8475383 DOI: 10.1126/Science.8475383  0.453
1993 Hartl P, Gottesfeld J, Forbes DJ. Mitotic repression of transcription in vitro. The Journal of Cell Biology. 120: 613-24. PMID 8381119 DOI: 10.1083/Jcb.120.3.613  0.427
1992 Liao XB, Clemens KR, Tennant L, Wright PE, Gottesfeld JM. Specific interaction of the first three zinc fingers of TFIIIA with the internal control region of the Xenopus 5 S RNA gene. Journal of Molecular Biology. 223: 857-71. PMID 1538401 DOI: 10.1016/0022-2836(92)90248-I  0.497
1992 Keller HJ, Romaniuk PJ, Gottesfeld JM. Interaction of Xenopus TFIIIC with the TFIIIA.5 S RNA gene complex. The Journal of Biological Chemistry. 267: 18190-8. PMID 1517247  0.372
1992 Clemens KR, Liao X, Wolf V, Wright PE, Gottesfeld JM. Definition of the binding sites of individual zinc fingers in the transcription factor IIIA-5S RNA gene complex. Proceedings of the National Academy of Sciences of the United States of America. 89: 10822-6. PMID 1438283 DOI: 10.1073/Pnas.89.22.10822  0.469
1991 Schroth GP, Gottesfeld JM, Bradbury EM. TFIIIA induced DNA bending: Effect of low ionic strength electrophoresis buffer conditions Nucleic Acids Research. 19: 511-516. PMID 2011525 DOI: 10.1093/Nar/19.3.511  0.465
1991 Lee MS, Gottesfeld JM, Wright PE. Zinc is required for folding and binding of a single zinc finger to DNA. Febs Letters. 279: 289-94. PMID 2001741 DOI: 10.1016/0014-5793(91)80170-8  0.385
1990 Keller HJ, You QM, Romaniuk PJ, Gottesfeld JM. Additional intragenic promoter elements of the Xenopus 5S RNA genes upstream from the TFIIIA-binding site. Molecular and Cellular Biology. 10: 5166-76. PMID 2398887 DOI: 10.1128/Mcb.10.10.5166  0.46
1990 Engelke DR, Gottesfeld JM. Chromosomal footprinting of transcriptionally active and inactive oocyte-type 5S RNA genes of Xenopus laevis. Nucleic Acids Research. 18: 6031-7. PMID 2235485 DOI: 10.1093/Nar/18.20.6031  0.489
1989 Gottesfeld JM. Analysis of RNA polymerase III transcription in vitro using chromatin and cloned gene templates. Methods in Enzymology. 170: 347-59. PMID 2770545 DOI: 10.1016/0076-6879(89)70055-0  0.452
1989 Schroth GP, Cook GR, Bradbury EM, Gottesfeld JM. Transcription factor IIIA induced bending of the Xenopus somatic 5S gene promoter. Nature. 340: 487-8. PMID 2755511 DOI: 10.1038/340487A0  0.518
1989 Millstein LS, Gottesfeld JM. Control of gene expression in eukaryotic cells: lessons from class III genes Current Opinion in Cell Biology. 1: 497-502. PMID 2697269 DOI: 10.1016/0955-0674(89)90011-2  0.784
1989 Blanco J, Millstein L, Razik MA, Dilworth S, Cote C, Gottesfeld J. Two TFIIIA activities regulate expression of the Xenopus 5S RNA gene families. Genes & Development. 3: 1602-12. PMID 2575558 DOI: 10.1101/Gad.3.10.1602  0.803
1989 Razik MA, Blanco J, Gottesfeld JM. Pathways of nucleoprotein assembly on 5S RNA genes in a Xenopus oocyte S-150 extract. Nucleic Acids Research. 17: 4117-30. PMID 2544856 DOI: 10.1093/Nar/17.11.4117  0.488
1988 Blanco J, Gottesfeld JM. Xenopus transcription factor IIIA forms a complex of covalent character with 5S DNA. Nucleic Acids Research. 16: 11267-84. PMID 3205743 DOI: 10.1093/Nar/16.23.11267  0.457
1987 Peck LJ, Millstein L, Eversole-Cire P, Gottesfeld JM, Varshavsky A. Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro. Molecular and Cellular Biology. 7: 3503-10. PMID 3683391 DOI: 10.1128/Mcb.7.10.3503  0.793
1987 Gottesfeld JM, Blanco J, Tennant LL. The 5S gene internal control region is B-form both free in solution and in a complex with TFIIIA. Nature. 329: 460-2. PMID 3657961 DOI: 10.1038/329460A0  0.495
1987 Gottesfeld JM. DNA sequence-directed nucleosome reconstitution on 5S RNA genes of Xenopus laevis. Molecular and Cellular Biology. 7: 1612-22. PMID 3600640 DOI: 10.1128/Mcb.7.5.1612  0.53
1987 Millstein L, Eversole-Cire P, Blanco J, Gottesfeld JM. Differential transcription of Xenopus oocyte and somatic-type 5 S genes in a Xenopus oocyte extract. The Journal of Biological Chemistry. 262: 17100-10. PMID 2445754  0.351
1986 Gottesfeld JM. Novobiocin inhibits RNA polymerase III transcription in vitro by a mechanism distinct from DNA topoisomerase II. Nucleic Acids Research. 14: 2075-88. PMID 3008085 DOI: 10.1093/Nar/14.5.2075  0.473
1985 Reynolds WF, Gottesfeld JM. Torsional stress induces an S1 nuclease-hypersensitive site within the promoter of the Xenopus laevis oocyte-type 5S RNA gene. Proceedings of the National Academy of Sciences of the United States of America. 82: 4018-22. PMID 2987960 DOI: 10.1073/Pnas.82.12.4018  0.453
1985 Bazett-Jones DP, Yeckel M, Gottesfeld JM. Nuclear extracts from globin-synthesizing cells enhance globin transcription in vitro. Nature. 317: 824-8. PMID 2414668 DOI: 10.1038/317824A0  0.491
1984 Sutcliffe JG, Milner RJ, Gottesfeld JM, Reynolds W. Control of neuronal gene expression. Science (New York, N.Y.). 225: 1308-15. PMID 6474179 DOI: 10.1126/Science.6474179  0.428
1984 von Beroldingen CH, Reynolds WF, Millstein L, Bazett-Jones DP, Gottesfeld JM. Eukaryotic transcription complexes. Molecular and Cellular Biochemistry. 62: 97-108. PMID 6379414 DOI: 10.1007/Bf00223300  0.819
1984 Gottesfeld JM, Andrews DL, Hoch SO. Association of an RNA polymerase III transcription factor with a ribonucleoprotein complex recognized by autoimmune sera. Nucleic Acids Research. 12: 3185-200. PMID 6232502 DOI: 10.1093/Nar/12.7.3185  0.394
1984 Sutcliffe JG, Milner RJ, Gottesfeld JM, Lerner RA. Identifier sequences are transcribed specifically in brain. Nature. 308: 237-41. PMID 6199680 DOI: 10.1038/308237A0  0.379
1984 Andrews DL, Millstein L, Hamkalo BA, Gottesfeld JM. Competition between Xenopus satellite I sequences and Pol III genes for stable transcription complex formation. Nucleic Acids Research. 12: 7753-69. PMID 6093052 DOI: 10.1093/Nar/12.20.7753  0.826
1983 Reynolds WF, Bloomer LS, Gottesfeld JM. Control of 5S RNA transcription in Xenopus somatic cell chromatin: activation with an oocyte extract. Nucleic Acids Research. 11: 57-75. PMID 6866764 DOI: 10.1093/Nar/11.1.57  0.463
1983 Reynolds WF, Gottesfeld JM. 5S rRNA gene transcription factor IIIA alters the helical configuration of DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 1862-6. PMID 6572947 DOI: 10.1073/Pnas.80.7.1862  0.514
1982 Gottesfeld J, Bloomer LS. Assembly of transcriptionally active 5S RNA gene chromatin in vitro. Cell. 28: 781-91. PMID 7201351 DOI: 10.1016/0092-8674(82)90057-5  0.491
1980 Gottesfeld JM, Bloomer LS. Nonrandom alignment of nucleosomes on 5S RNA genes of X. laevis Cell. 21: 751-760. PMID 7438206 DOI: 10.1016/0092-8674(80)90438-9  0.524
1978 Gottesfeld JM, Melton DA. The length of nucleosome-associated DNA is the same in both transcribed and nontranscribed regions of chromatin. Nature. 273: 317-9. PMID 652040 DOI: 10.1038/273317A0  0.481
1978 Gottesfeld JM. Organization of transcribed regions of chromatin Philosophical Transactions of the Royal Society of London Series B Biological Sciences. 283: 343-357. PMID 26080 DOI: 10.1098/Rstb.1978.0036  0.45
1977 Gottesfeld JM, Butler PJG. Structure of transcriptionally-active chromatin subunits Nucleic Acids Research. 4: 3155-3174. PMID 909802 DOI: 10.1093/Nar/4.9.3155  0.439
1977 Gottesfeld JM, Partington GA. Distribution of messenger RNA-coding sequences in fractionated chromatin Cell. 12: 953-962. PMID 597865 DOI: 10.1016/0092-8674(77)90160-X  0.419
1977 Gottesfeld JM. Methods for fractionation of chromatin into transcriptionally active and inactive segments Methods in Cell Biology. 16: 421-436. PMID 329060 DOI: 10.1016/S0091-679X(08)60117-X  0.363
1976 Gottesfeld JM, Bagi G, Berg B, Bonner J. Sequence composition of the template-active fraction of rat liver chromatin Biochemistry. 15: 2472-2483. PMID 179568 DOI: 10.1021/Bi00656A034  0.579
1975 Gottesfeld JM, Murphy RF, Bonner J. Structure of transcriptionally active chromatin Proceedings of the National Academy of Sciences of the United States of America. 72: 4404-4408. PMID 1060119 DOI: 10.1073/Pnas.72.11.4404  0.594
1975 Bonner J, Gottesfeld J, Garrard W, Billing R, Uphouse L. [8] Isolation of template active and inactive regions of chromatin Methods in Enzymology. 40: 97-102. PMID 164611 DOI: 10.1016/S0076-6879(75)40010-6  0.567
1974 Gottesfeld JM, Garrard WT, Bagi G, Wilson RF, Bonner J. Partial purification of the template active fraction of chromatin: a preliminary report Proceedings of the National Academy of Sciences of the United States of America. 71: 2193-2197. PMID 4526205 DOI: 10.1073/Pnas.71.6.2193  0.633
1974 Bonner J, Garrard WT, Gottesfeld J, Holmes DS. Functional organization of the mammalian genome. Cold Spring Harbor Symposia On Quantitative Biology. 38: 303-10. PMID 4524761 DOI: 10.1101/Sqb.1974.038.01.034  0.46
1971 Gottesfeld JM, Adams NH, el-Badry AM, Moses V, Calvin M. The inhibition of deoxyribonuclease I by hydroxybiphenyls. Biochimica Et Biophysica Acta. 228: 365-86. PMID 5101930 DOI: 10.1016/0005-2787(71)90044-X  0.326
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