Year |
Citation |
Score |
2009 |
Moreau RJ, Schubert CR, Nasr KA, Török M, Miller JS, Kennedy RJ, Kemp DS. Context-independent, temperature-dependent helical propensities for amino acid residues. Journal of the American Chemical Society. 131: 13107-16. PMID 19702302 DOI: 10.1021/Ja904271K |
0.315 |
|
2009 |
Nasr KA, Schubert CR, Török M, Kennedy RJ, Kemp DS. Helix-coil energetics for helix formers and breakers reflect context and temperature: mutants of helically robust, guest-sensitive homopeptide hosts. Biopolymers. 91: 311-20. PMID 19117030 DOI: 10.1002/Bip.21129 |
0.322 |
|
2006 |
Job GE, Kennedy RJ, Heitmann B, Miller JS, Walker SM, Kemp DS. Temperature- and length-dependent energetics of formation for polyalanine helices in water: assignment of w(Ala)(n,T) and temperature-dependent CD ellipticity standards. Journal of the American Chemical Society. 128: 8227-33. PMID 16787087 DOI: 10.1021/Ja060094Y |
0.342 |
|
2005 |
Kennedy RJ, Walker SM, Kemp DS. Energetic characterization of short helical polyalanine peptides in water: analysis of 13C=O chemical shift data. Journal of the American Chemical Society. 127: 16961-8. PMID 16316242 DOI: 10.1021/Ja054645G |
0.357 |
|
2005 |
Heitmann B, Job GE, Kennedy RJ, Walker SM, Kemp DS. Water-solubilized, cap-stabilized, helical polyalanines: calibration standards for NMR and CD analyses. Journal of the American Chemical Society. 127: 1690-704. PMID 15701003 DOI: 10.1021/Ja0457462 |
0.371 |
|
2003 |
Wallimann P, Kennedy RJ, Miller JS, Shalongo W, Kemp DS. Dual wavelength parametric test of two-state models for circular dichroism spectra of helical polypeptides: anomalous dichroic properties of alanine-rich peptides. Journal of the American Chemical Society. 125: 1203-20. PMID 12553823 DOI: 10.1021/Ja0275360 |
0.355 |
|
2002 |
Miller JS, Kennedy RJ, Kemp DS. Solubilized, spaced polyalanines: a context-free system for determining amino acid alpha-helix propensities. Journal of the American Chemical Society. 124: 945-62. PMID 11829602 DOI: 10.1021/Ja011726D |
0.368 |
|
2002 |
Kennedy RJ, Tsang KY, Kemp DS. Consistent helicities from CD and template t/c data for N-templated polyalanines: progress toward resolution of the alanine helicity problem. Journal of the American Chemical Society. 124: 934-44. PMID 11829601 DOI: 10.1021/Ja016285C |
0.344 |
|
2002 |
Kemp DS. Construction and analysis of Lifson - Roig models for the helical conformations of α-peptides Helvetica Chimica Acta. 85: 4392-4423. DOI: 10.1002/Hlca.200290019 |
0.391 |
|
2001 |
Maison W, Kennedy RJ, Kemp DS. Chaotropic Anions Strongly Stabilize Short, N-Capped Uncharged Peptide Helicies: A New Look at the Perchlorate Effect. Angewandte Chemie (International Ed. in English). 40: 3819-3821. PMID 29712130 DOI: 10.1002/1521-3773(20011015)40:20<3819::Aid-Anie3819>3.0.Co;2-S |
0.642 |
|
2001 |
Maison W, Kennedy RJ, Kemp DS. Chaotropic Anions Strongly Stabilize Short, N-Capped Uncharged Peptide Helicies: A New Look at the Perchlorate Effect This research was supported by NIH GM 13453, by the NSF 9121702-CHE, by Pfizer Research, and by the award of a Feodor Lynen Fellowship from the Alexander von Humboldt-Stiftung to W.M. Angewandte Chemie (International Ed. in English). 40: 3819-3821. PMID 11668543 DOI: 10.1002/1521-3773(20011015)40:20<3819::AID-ANIE3819>3.0.CO;2-S |
0.599 |
|
2001 |
Maison W, Arce E, Renold P, Kennedy RJ, Kemp DS. Optimal N-caps for N-terminal helical templates: effects of changes in H-bonding efficiency and charge. Journal of the American Chemical Society. 123: 10245-54. PMID 11603974 DOI: 10.1021/Ja010812A |
0.642 |
|
2001 |
Miller JS, Kennedy RJ, Kemp DS. Short, solubilized polyalanines are conformational chameleons: exceptionally helical if N- and C-capped with helix stabilizers, weakly to moderately helical if capped with rigid spacers. Biochemistry. 40: 305-9. PMID 11148022 DOI: 10.1021/Bi0019500 |
0.356 |
|
2001 |
Maison W, Kennedy RJ, Miller JS, Kemp DS. C-terminal helix capping propensities in a polyalanine context for amino acids bearing nonpolar aliphatic side chains Tetrahedron Letters. 42: 4975-4977. DOI: 10.1016/S0040-4039(01)00922-4 |
0.641 |
|
2001 |
Maison W, Kennedy RJ, Kemp DS. Stabilisierung kurzer, ungeladener Peptidhelices durch chaotrope Anionen – Neues zum Perchlorat‐Effekt Angewandte Chemie. 113: 3936-3938. DOI: 10.1002/1521-3757(20011015)113:20<3936::Aid-Ange3936>3.0.Co;2-J |
0.549 |
|
2000 |
Deechongkit S, Kennedy RJ, Kwok Yin Tsang, Renold P, Kemp DS. An amino acid that controls polypeptide helicity: β-amino alanine, the first strongly stabilizing C-terminal helix stop signal Tetrahedron Letters. 41: 9679-9683. DOI: 10.1016/S0040-4039(00)01750-0 |
0.329 |
|
1999 |
Wallimann P, Kennedy RJ, Kemp DS. Large Circular Dichroism Ellipticities for N-Templated Helical Polypeptides Are Inconsistent with Currently Accepted Helicity Algorithms. Angewandte Chemie (International Ed. in English). 38: 1290-1292. PMID 29711746 DOI: 10.1002/(Sici)1521-3773(19990503)38:9<1290::Aid-Anie1290>3.0.Co;2-E |
0.422 |
|
1999 |
Wallimann P, Kennedy RJ, Kemp DS. Große Circulardichroismus-Elliptizitäten für Polypeptide mit N-terminal induzierter Helixkonformation sind nicht in Einklang mit den derzeit akzeptierten Helizitätsalgorithmen Angewandte Chemie. 111: 1377-1379. DOI: 10.1002/(Sici)1521-3757(19990503)111:9<1377::Aid-Ange1377>3.0.Co;2-E |
0.322 |
|
1996 |
Groebke K, Renold P, Tsang KY, Allen TJ, McClure KF, Kemp DS. Template-nucleated alanine-lysine helices are stabilized by position-dependent interactions between the lysine side chain and the helix barrel. Proceedings of the National Academy of Sciences of the United States of America. 93: 4025-9. PMID 8633010 |
0.306 |
|
1996 |
Renold P, Tsang KY, Shimizu LS, Kemp DS. For short alanine-lysine peptides the helical propensities of lysine residues (s values) are strongly temperature dependent Journal of the American Chemical Society. 118: 12234-12235. DOI: 10.1021/Ja961646N |
0.643 |
|
1995 |
Kemp DS, Rothman JH. Efficient helix nucleation by a macrocyclic triproline-derived template Tetrahedron Letters. 36: 4023-4026. DOI: 10.1016/0040-4039(95)00707-J |
0.371 |
|
1995 |
Kemp DS, Rothman JH. Conformational analysis of a triproline-derived helical template and its peptide conjugates Tetrahedron Letters. 36: 3813-3816. DOI: 10.1016/0040-4039(95)00673-Z |
0.386 |
|
1993 |
Fotouhi N, Kemp DS. Novel class of silicon-based protective groups for the side chain of tyrosine. International Journal of Peptide and Protein Research. 41: 153-61. PMID 8458689 DOI: 10.1111/J.1399-3011.1993.Tb00126.X |
0.383 |
|
1993 |
Kemp DS, Carey RI. Synthesis of a 39-peptide and a 25-peptide by thiol capture ligations: Observation of a 40-fold rate acceleration of the intramolecular O,N-acyl-transfer reaction between peptide fragments bearing only cysteine protective groups Journal of Organic Chemistry. 58: 2216-2222. |
0.322 |
|
1992 |
Fotouhi N, Bowen BR, Kemp DS. Resolution of proline acylation problem for thiol capture strategy by use of a chloro-dibenzofuran template. International Journal of Peptide and Protein Research. 40: 141-7. PMID 1280251 DOI: 10.1111/J.1399-3011.1992.Tb01462.X |
0.416 |
|
1991 |
Kemp DS, Boyd JG, Muendel CC. The helical s constant for alanine in water derived from template-nucleated helices. Nature. 352: 451-4. PMID 1861726 DOI: 10.1038/352451A0 |
0.36 |
|
1990 |
Kemp DS. Peptidomimetics and the template approach to nucleation of beta-sheets and alpha-helices in peptides. Trends in Biotechnology. 8: 249-55. PMID 1366733 DOI: 10.1016/0167-7799(90)90187-3 |
0.379 |
|
1989 |
Kemp DS, Carter JS. Amino acid derivatives that stabilize secondary structures of polypeptides. 4. Practical synthesis of 4-(alkylamino)-3-cyano-6-azabicyclo[3.2.1]oct-3-enes (ben derivatives) as γ-turn templates Journal of Organic Chemistry. 54: 109-115. DOI: 10.1021/Jo00262A026 |
0.335 |
|
1989 |
Kemp DS, Carey RI. Boc-L-Dmt-OH as a fully N,S-blocked cysteine derivative for peptide synthesis by prior thiol capture. Facile conversion of N-terminal Boc-L-Dmt-peptides to H-Cys(Scm)-peptides Journal of Organic Chemistry. 54: 3640-3646. |
0.318 |
|
1989 |
Fotouhi N, Galakatos NG, Kemp DS. Peptide synthesis by prior thiol capture. 6. Rates of the disulfide bond forming capture reaction and demonstration of the overall strategy by synthesis of the C-terminal 29-peptide sequence of BPTI Journal of Organic Chemistry. 54: 2803-2817. |
0.301 |
|
1988 |
Kemp DS, Fotouhi N, Boyd JG, Carey RI, Ashton C, Hoare J. Practical preparation and deblocking conditions for N-alpha-(2-(p-biphenylyl)-2-propyloxycarbonyl)-amino acid (N-a-Bpoc-Xxx-OH) derivatives. International Journal of Peptide and Protein Research. 31: 359-72. PMID 3391743 DOI: 10.1111/J.1399-3011.1988.Tb00045.X |
0.359 |
|
1987 |
Kemp DS, Carter JS. Amino acid derivatives that stabilize secondary structures of polypeptides-IV. Practical synthesis of 4-alkyamino-3-cyano-azabicyclo[3.2.1.]oct-3-enes (Ben derivatives) as γ-turn templates Tetrahedron Letters. 28: 4645-4648. DOI: 10.1016/S0040-4039(00)96586-9 |
0.331 |
|
1987 |
McBride BJ, Kemp DS. Peptide synthesis by prior thiol capture...III. Assessment of levels of racemization during two typical thiol capture coupling reactions Tetrahedron Letters. 28: 3435-3438. DOI: 10.1016/S0040-4039(00)96319-6 |
0.32 |
|
1986 |
Kemp DS, Galakatos NG, Dranginis S, Ashton C, Fotouhi N, Curran TP. Peptide synthesis by prior thiol capture. 4. Amide bond formation: The effect of a side-chain substituent on the rates of intramolecular O,N-acyl transfer Journal of Organic Chemistry. 51: 3320-3324. |
0.3 |
|
1981 |
Vellaccio F, Phelan JM, Trottier RL, Napier TW, Kemp DS. Catechol and substituted catechol-derived ortho esters, models for protected active esters in peptide synthesis Journal of Organic Chemistry. 46: 3087-3091. DOI: 10.1021/Jo00328A020 |
0.396 |
|
1981 |
Kemp DS, Kerkman DJ, Leung SL, Hanson G. Intramolecular O,N-acyl transfer via cyclic intermediates of nine and twelve members. Models for extensions of the amine capture strategy for peptide synthesis Journal of Organic Chemistry. 46: 490-498. DOI: 10.1021/Jo00316A003 |
0.407 |
|
1981 |
Kemp DS. The amine capture strategy for peptide bond formation—an outline of progress Biopolymers. 20: 1793-1804. DOI: 10.1002/Bip.1981.360200904 |
0.388 |
|
1980 |
Roberts DC, Suda K, Samanen J, Kemp DS. Pluripotential amino acids I. (L)-p-dihydroxyborylphenylalanine (L-Bph) as a precursor of L-Phe and L-Tyr containing peptides; specific tritiation of L-Phe-containing peptides at a final step in synthesis Tetrahedron Letters. 21: 3435-3438. DOI: 10.1016/S0040-4039(00)78708-9 |
0.359 |
|
1979 |
Kemp DS, Garst ME, Harper RW, Cox DD, Carlson D, Denmark S. Synthesis of cyclophanes derived from 1-amino-3,7-dialkyl-4-methylnaphthalenes Journal of Organic Chemistry. 44: 4469-4473. DOI: 10.1002/Chin.198014210 |
0.336 |
|
1977 |
Kemp DS, Reczek J. New protective groups for peptide synthesis--III the maq ester group mild reductive cleavage of 2-acyloxymethyleneanthraquinones Tetrahedron Letters. 18: 1031-1034. DOI: 10.1016/S0040-4039(01)92820-5 |
0.359 |
|
1976 |
KEMP DS, HOYNG CF, ROBERTS DC. ChemInform Abstract: New Protective Groups for Peptide Synthesis. Part l. The Bic Group.Base and Solvent Lability of the 5-Benzisoxazolylmethyleneoxycarbonylamino Function. Part 2. The Dobz Group. Boron-derived Affinity Protection with the p-Dihydroxybory Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197612401 |
0.337 |
|
1976 |
KEMP DS, VELLACCIO FJ. ChemInform Abstract: ANOMALOUSLY LARGE STERIC INHIBITION OF INTRAMOLECULAR O,N-ACYL TRANSFER TO AMINO ACID ESTERS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197608168 |
0.336 |
|
1975 |
Kemp DS, Grattan JA, Reczek J. Letter: Peptide bond formation by the amine capture principle. The Journal of Organic Chemistry. 40: 3465-6. PMID 1185322 DOI: 10.1021/Jo00911A044 |
0.38 |
|
1975 |
Kemp DS, Vellaccio F. Letter: Anomalously large steric inhibition of intramolecular O,N-acyl transfer to amino acid esters. The Journal of Organic Chemistry. 40: 3464-4. PMID 1185321 DOI: 10.1021/Jo00911A043 |
0.33 |
|
1975 |
Kemp DS, Vellaccio F. Rapid intramolecular acyl transfer from phenol to carbinolamine--progress toward a new class of peptide coupling reagent. The Journal of Organic Chemistry. 40: 3003-4. PMID 1177079 DOI: 10.1002/Chin.197601347 |
0.365 |
|
1975 |
Kemp DS, Roberts DC. New protective groups for peptide synthesis-II the Dobz group boron-derived affinity protection with the p-dihydroxyborylbenzyloxycarbonylamino function Tetrahedron Letters. 16: 4629-4632. DOI: 10.1016/S0040-4039(00)91037-2 |
0.342 |
|
1975 |
Kemp DS, Hoyng CF. New protective groups for peptide synthesis-I the Bic group base and solvent lability of the 5-benzisoxazolylmetheleneoxycarbonylamino function Tetrahedron Letters. 16: 4625-4628. DOI: 10.1016/S0040-4039(00)91036-0 |
0.357 |
|
1975 |
KEMP DS, WANG S, REBEK JJ, MOLLAN RC, BANQUER C, SUBRAMANYAM G. ChemInform Abstract: PEPTIDE SYNTHESIS WITH BENZISOXAZOLIUM SALTS PART 2, ACTIVATION CHEMISTRY OF 2-ETHYL-7-HYDROXYBENZISOXAZOLIUM FLUOROBORATE, COUPLING CHEMISTRY OF 3-ACYLOXY-2-HYDROXY-N-ETHYLBENZAMIDES Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/chin.197507460 |
0.319 |
|
1974 |
Kemp DS, Bernstein ZW, McNeil GN. Nucleophilic reactivity of peptides toward 2-acyloxy-N-ethylbenzamides. The utility of free peptides as nucleophiles in amide bond forming reactions. The Journal of Organic Chemistry. 39: 2831-5. PMID 4414859 |
0.316 |
|
1974 |
Kemp DS, Wrobel SJ, Wang SW, Bernstein Z, Rebek J. Peptide synthesis with benzisoxazolium salts-III. Utility of 7-hydroxy-2-ethylbenzisoxazolium fluoroborate in the synthesis of peptides Tetrahedron. 30: 3969-3980. DOI: 10.1016/S0040-4020(01)97372-7 |
0.452 |
|
1974 |
Kemp DS, Wang SW, Rebek J, Mollan RC, Banquer C, Subramanyam G. Peptide synthesis with benzisoxazolium salts-II. Activation chemistry of 2-ethyl-7-hydroxybenzisoxazolium fluroborate; Coupling chemistry of 3-acyloxy-2-hydroxy-N-ethylbenzamides Tetrahedron. 30: 3955-3967. DOI: 10.1016/S0040-4020(01)97371-5 |
0.438 |
|
1974 |
Kemp DS, Wang SW, Mollan RC, Hsia SL, Confalone PN. Peptide synthesis with benzisoxazolium salts-I. Properties of substituted 2-ethyl-benzisoxazolium salts Tetrahedron. 30: 3677-3688. DOI: 10.1016/S0040-4020(01)90651-9 |
0.396 |
|
1970 |
Kemp DS, Rebek J. Peptide racemization mechanism. A kinetic isotope effect as a means of distinguishing enolization from oxazolone formation. Journal of the American Chemical Society. 92: 5792-3. PMID 5458746 DOI: 10.1021/Ja00722A071 |
0.375 |
|
1970 |
Kemp DS, Bernstein Z, Rebeck J. Racemization during peptide couplings using the mixed anhydride, N-hydroxysuccinimide ester, 8-hydroxyquinoline ester, and acyl azide methods. Journal of the American Chemical Society. 92: 4756-7. PMID 5428884 |
0.31 |
|
1970 |
Coburn RA, Landesberg JM, Kemp DS, Olofson RA. An addition-elimination mechanism for CH/CD exchange in thiazole Tetrahedron. 26: 685-692. DOI: 10.1016/S0040-4020(01)97862-7 |
0.49 |
|
1970 |
Kemp DS, Rebek JJ. Mechanismus Der Peptid-Racemisierung, Kinetischer Isotopeneffekt Als Mittel Zur Unterscheidung Der Enolisierung Von Der Oxazolon-Bildung Cheminform. 1. DOI: 10.1002/Chin.197049163 |
0.335 |
|
1967 |
Goodfriend T, Fasman G, Kemp D, Levine L. Immunochemical studies of angiotensin. Immunochemistry. 3: 223-31. PMID 4289221 DOI: 10.1016/0019-2791(66)90186-8 |
0.322 |
|
1965 |
Kemp DS, Woodward RB. The N-ethylbenzisoxazolium cation-I. Preparation and reactions with nucleophilic species Tetrahedron. 21: 3019-3035. |
0.445 |
|
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