Stephen G. Sligar - Publications

Affiliations: 
Molecular and Cellular Biology University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
metalloenzymes
Website:
https://chemistry.illinois.edu/s-sligar

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Year Citation  Score
2021 Liu Y, Denisov IG, Sligar SG, Kincaid JR. Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome . Journal of the American Chemical Society. PMID 33656879 DOI: 10.1021/jacs.1c00581  0.76
2020 Sligar SG, Denisov IG. Nanodiscs: A Toolkit for Membrane Protein Science. Protein Science : a Publication of the Protein Society. PMID 33165998 DOI: 10.1002/pro.3994  0.76
2020 McLean MA, Denisov IG, Grinkova YV, Sligar SG. Dark, Ultra-Dark and Ultra-Bright Nanodiscs for membrane protein investigations. Analytical Biochemistry. 113860. PMID 32750355 DOI: 10.1016/j.ab.2020.113860  0.76
2020 Liu Y, Denisov I, Grinkova Y, Sligar S, Kincaid JR. P450 CYP17A1 variant with a disordered proton shuttle assembly retains peroxo-mediated lyase efficiency. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32681807 DOI: 10.1002/chem.202003181  0.48
2019 Ivanova L, Denisov IG, Grinkova YV, Sligar SG, Fæste CK. Biotransformation of the Mycotoxin Enniatin B1 by CYP P450 3A4 and Potential for Drug-Drug Interactions. Metabolites. 9. PMID 31357617 DOI: 10.3390/metabo9080158  0.76
2019 McLean MA, Stephen AG, Sligar SG. PIP2 Influences the Conformational Dynamics of Membrane bound KRAS4b. Biochemistry. PMID 31339036 DOI: 10.1021/acs.biochem.9b00395  0.56
2019 Denisov IG, Schuler MA, Sligar SG. Nanodiscs as a New Tool to Examine Lipid-Protein Interactions. Methods in Molecular Biology (Clifton, N.J.). 2003: 645-671. PMID 31218635 DOI: 10.1007/978-1-4939-9512-7_25  0.76
2019 Denisov IG, Grinkova YV, Nandigrami P, Shekhar M, Tajkhorshid E, Sligar SG. Correction to "Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213". Biochemistry. PMID 31181900 DOI: 10.1021/acs.biochem.9b00438  0.76
2019 Denisov IG, Grinkova YV, Nandigrami P, Shekhar M, Tajkhorshid E, Sligar SG. Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213. Biochemistry. PMID 30785734 DOI: 10.1021/acs.biochem.8b01268  0.76
2018 Duggal R, Denisov IG, Sligar SG. Cytochrome b enhances androgen synthesis by rapidly reducing the CYP17A1 oxy-complex in the lyase step. Febs Letters. PMID 29888793 DOI: 10.1002/1873-3468.13153  0.76
2018 Mak PJ, Duggal R, Denisov IG, Gregory MC, Sligar SG, Kincaid JR. Human cytochrome CYP17A1. The structural basis for compromised lyase activity with 17-hydroxyprogesterone. Journal of the American Chemical Society. PMID 29758981 DOI: 10.1021/jacs.8b03901  0.76
2018 McLean MA, Gregory MC, Sligar SG. Nanodiscs: A Controlled Bilayer Surface for the Study of Membrane Proteins. Annual Review of Biophysics. PMID 29494254 DOI: 10.1146/annurev-biophys-070816-033620  0.56
2017 Gregory MC, Mak PJ, Khatri Y, Kincaid JR, Sligar SG. Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202. Biochemistry. PMID 29283561 DOI: 10.1021/acs.biochem.7b01067  0.4
2017 Denisov IG, Baylon JL, Grinkova YV, Tajkhorshid E, Sligar SG. Drug-Drug Interactions between Atorvastatin and Dronedarone Mediated by Monomeric CYP3A4. Biochemistry. PMID 29200287 DOI: 10.1021/acs.biochem.7b01012  0.76
2017 Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, ... ... Sligar SG, et al. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chemical Biology. 24: 1314. PMID 29053951 DOI: 10.1016/j.chembiol.2017.09.012  0.76
2017 Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, ... ... Sligar SG, et al. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chemical Biology. PMID 28919040 DOI: 10.1016/j.chembiol.2017.08.009  0.76
2017 Wade JH, Jones JD, Lenov IL, Riordan CM, Sligar SG, Bailey RC. Microfluidic platform for efficient Nanodisc assembly, membrane protein incorporation, and purification. Lab On a Chip. PMID 28767110 DOI: 10.1039/c7lc00601b  0.72
2017 Gregory MC, McLean MA, Sligar SG. Interaction of KRas4b with anionic membranes: A special role for PIP2. Biochemical and Biophysical Research Communications. PMID 28412347 DOI: 10.1016/j.bbrc.2017.04.063  0.56
2017 Van Eps N, Caro LN, Morizumi T, Kusnetzow AK, Szczepek M, Hofmann KP, Bayburt TH, Sligar SG, Ernst OP, Hubbell WL. Conformational equilibria of light-activated rhodopsin in nanodiscs. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373559 DOI: 10.1073/pnas.1620405114  0.48
2017 DiChiara T, DiNunno N, Clark J, Bu RL, Cline EN, Rollins MG, Gong Y, Brody DL, Sligar SG, Velasco PT, Viola KL, Klein WL. Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station. The Yale Journal of Biology and Medicine. 90: 45-61. PMID 28356893  0.32
2017 Denisov IG, Sligar SG. Nanodiscs in Membrane Biochemistry and Biophysics. Chemical Reviews. PMID 28177242 DOI: 10.1021/acs.chemrev.6b00690  0.76
2016 Her C, Filoti DI, McLean MA, Sligar SG, Alexander Ross JB, Steele H, Laue TM. The Charge Properties of Phospholipid Nanodiscs. Biophysical Journal. 111: 989-98. PMID 27602726 DOI: 10.1016/j.bpj.2016.06.041  0.56
2016 Ye X, McLean MA, Sligar SG. PIP2 Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates its Auto- Inhibited Form. Biochemistry. PMID 27548281 DOI: 10.1021/acs.biochem.6b00497  1
2016 Duggal R, Liu Y, Gregory MC, Denisov IG, Kincaid JR, Sligar SG. Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis. Biochemical and Biophysical Research Communications. PMID 27297105 DOI: 10.1016/j.bbrc.2016.06.043  0.76
2016 Denisov IG, Sligar SG. Nanodiscs for structural and functional studies of membrane proteins. Nature Structural & Molecular Biology. 23: 481-6. PMID 27273631 DOI: 10.1038/nsmb.3195  0.76
2016 Ye X, McLean MA, Sligar SG. Conformational equilibrium of talin is regulated by anionic lipids. Biochimica Et Biophysica Acta. PMID 27163494 DOI: 10.1016/j.bbamem.2016.05.005  1
2015 Denisov IG, Mak PJ, Grinkova YV, Bastien D, Bérubé G, Sligar SG, Kincaid JR. The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4. Journal of Inorganic Biochemistry. PMID 26774838 DOI: 10.1016/j.jinorgbio.2015.12.019  0.76
2015 Mak PJ, Gregory MC, Denisov IG, Sligar SG, Kincaid JR. Unveiling the crucial intermediates in androgen production. Proceedings of the National Academy of Sciences of the United States of America. 112: 15856-61. PMID 26668369 DOI: 10.1073/pnas.1519376113  0.76
2015 Skar-Gislinge N, Kynde SA, Denisov IG, Ye X, Lenov I, Sligar SG, Arleth L. Small-angle scattering determination of the shape and localization of human cytochrome P450 embedded in a phospholipid nanodisc environment. Acta Crystallographica. Section D, Biological Crystallography. 71: 2412-21. PMID 26627649 DOI: 10.1107/S1399004715018702  1
2015 Denisov IG, Sligar SG. Metalloproteins: The long and the short of it. Nature Chemistry. 7: 687-8. PMID 26291938 DOI: 10.1038/nchem.2335  1
2015 Wilcox KC, Marunde MR, Das A, Velasco PT, Kuhns BD, Marty MT, Jiang H, Luan CH, Sligar SG, Klein WL. Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers. Plos One. 10: e0125263. PMID 25928376 DOI: 10.1371/journal.pone.0125263  1
2015 Carney CE, Lenov IL, Baker CJ, MacRenaris KW, Eckermann AL, Sligar SG, Meade TJ. Nanodiscs as a Modular Platform for Multimodal MR-Optical Imaging. Bioconjugate Chemistry. 26: 899-905. PMID 25830565 DOI: 10.1021/acs.bioconjchem.5b00107  1
2015 Denisov IG, Grinkova YV, Baylon JL, Tajkhorshid E, Sligar SG. Mechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomer. Biochemistry. 54: 2227-39. PMID 25777547 DOI: 10.1021/acs.biochem.5b00079  1
2015 Denisov IG, Sligar SG. Activation of molecular oxygen in cytochromes P450 Cytochrome P450: Structure, Mechanism, and Biochemistry, Fourth Edition. 69-109. DOI: 10.1007/978-3-319-12108-6_3  1
2014 Khatri Y, Luthra A, Duggal R, Sligar SG. Kinetic solvent isotope effect in steady-state turnover by CYP19A1 suggests involvement of Compound 1 for both hydroxylation and aromatization steps. Febs Letters. 588: 3117-22. PMID 24997347 DOI: 10.1016/j.febslet.2014.06.050  1
2014 Mak PJ, Luthra A, Sligar SG, Kincaid JR. Resonance Raman spectroscopy of the oxygenated intermediates of human CYP19A1 implicates a compound i intermediate in the final lyase step. Journal of the American Chemical Society. 136: 4825-8. PMID 24645879 DOI: 10.1021/ja500054c  1
2014 Marty MT, Zhang H, Cui W, Gross ML, Sligar SG. Interpretation and deconvolution of nanodisc native mass spectra. Journal of the American Society For Mass Spectrometry. 25: 269-77. PMID 24353133 DOI: 10.1007/s13361-013-0782-y  1
2014 Mak PJ, Gregory MC, Sligar SG, Kincaid JR. Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17. Biochemistry. 53: 90-100. PMID 24328388 DOI: 10.1021/bi4014424  1
2014 D'Antona AM, Xie G, Sligar SG, Oprian DD. Assembly of an activated rhodopsin-transducin complex in nanoscale lipid bilayers. Biochemistry. 53: 127-34. PMID 24328127 DOI: 10.1021/bi4012995  1
2014 Khatri Y, Gregory MC, Grinkova YV, Denisov IG, Sligar SG. Active site proton delivery and the lyase activity of human CYP17A1. Biochemical and Biophysical Research Communications. 443: 179-84. PMID 24299954 DOI: 10.1016/j.bbrc.2013.11.094  1
2013 Gregory MC, Denisov IG, Grinkova YV, Khatri Y, Sligar SG. Kinetic solvent isotope effect in human P450 CYP17A1-mediated androgen formation: evidence for a reactive peroxoanion intermediate. Journal of the American Chemical Society. 135: 16245-7. PMID 24160919 DOI: 10.1021/ja4086403  1
2013 Sun Y, Zeng W, Benabbas A, Ye X, Denisov I, Sligar SG, Du J, Dawson JH, Champion PM. Investigations of heme ligation and ligand switching in cytochromes p450 and p420. Biochemistry. 52: 5941-51. PMID 23905516 DOI: 10.1021/bi400541v  1
2013 Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, Sligar SG, Tesmer JJ, Schertler GF, Standfuss J, Gurevich VV. Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding. Cellular Signalling. 25: 2155-62. PMID 23872075 DOI: 10.1016/j.cellsig.2013.07.009  1
2013 Numata M, Grinkova YV, Mitchell JR, Chu HW, Sligar SG, Voelker DR. Nanodiscs as a therapeutic delivery agent: inhibition of respiratory syncytial virus infection in the lung. International Journal of Nanomedicine. 8: 1417-27. PMID 23717040 DOI: 10.2147/IJN.S39888  1
2013 Baylon JL, Lenov IL, Sligar SG, Tajkhorshid E. Characterizing the membrane-bound state of cytochrome P450 3A4: structure, depth of insertion, and orientation. Journal of the American Chemical Society. 135: 8542-51. PMID 23697766 DOI: 10.1021/ja4003525  1
2013 Gregory M, Mak PJ, Sligar SG, Kincaid JR. Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry. Angewandte Chemie (International Ed. in English). 52: 5342-5. PMID 23576395 DOI: 10.1002/anie.201300760  1
2013 Luthra A, Gregory M, Grinkova YV, Denisov IG, Sligar SG. Nanodiscs in the studies of membrane-bound cytochrome P450 enzymes. Methods in Molecular Biology (Clifton, N.J.). 987: 115-27. PMID 23475672 DOI: 10.1007/978-1-62703-321-3_10  1
2013 Sloan CD, Marty MT, Sligar SG, Bailey RC. Interfacing lipid bilayer nanodiscs and silicon photonic sensor arrays for multiplexed protein-lipid and protein-membrane protein interaction screening. Analytical Chemistry. 85: 2970-6. PMID 23425255 DOI: 10.1021/ac3037359  1
2013 Schuler MA, Denisov IG, Sligar SG. Nanodiscs as a new tool to examine lipid-protein interactions. Methods in Molecular Biology (Clifton, N.J.). 974: 415-33. PMID 23404286 DOI: 10.1007/978-1-62703-275-9_18  1
2013 Marty MT, Wilcox KC, Klein WL, Sligar SG. Nanodisc-solubilized membrane protein library reflects the membrane proteome. Analytical and Bioanalytical Chemistry. 405: 4009-16. PMID 23400332 DOI: 10.1007/s00216-013-6790-8  1
2013 Grinkova YV, Denisov IG, McLean MA, Sligar SG. Oxidase uncoupling in heme monooxygenases: human cytochrome P450 CYP3A4 in Nanodiscs. Biochemical and Biophysical Research Communications. 430: 1223-7. PMID 23266608 DOI: 10.1016/j.bbrc.2012.12.072  1
2012 Marty MT, Zhang H, Cui W, Blankenship RE, Gross ML, Sligar SG. Native mass spectrometry characterization of intact nanodisc lipoprotein complexes. Analytical Chemistry. 84: 8957-60. PMID 23061736 DOI: 10.1021/ac302663f  1
2012 Marty MT, Sloan CD, Bailey RC, Sligar SG. Nonlinear analyte concentration gradients for one-step kinetic analysis employing optical microring resonators. Analytical Chemistry. 84: 5556-64. PMID 22686186 DOI: 10.1021/ac300478f  1
2012 Denisov IG, Grinkova YV, Sligar SG. Cryoradiolysis and cryospectroscopy for studies of heme-oxygen intermediates in cytochromes p450. Methods in Molecular Biology (Clifton, N.J.). 875: 375-91. PMID 22573452 DOI: 10.1007/978-1-61779-806-1_20  1
2012 Morrissey JH, Tajkhorshid E, Sligar SG, Rienstra CM. Tissue factor/factor VIIa complex: role of the membrane surface. Thrombosis Research. 129: S8-10. PMID 22417943 DOI: 10.1016/j.thromres.2012.02.019  1
2012 Dalal K, Chan CS, Sligar SG, Duong F. Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase. Proceedings of the National Academy of Sciences of the United States of America. 109: 4104-9. PMID 22378651 DOI: 10.1073/pnas.1117783109  1
2012 Denisov IG, Sligar SG. A novel type of allosteric regulation: functional cooperativity in monomeric proteins. Archives of Biochemistry and Biophysics. 519: 91-102. PMID 22245335 DOI: 10.1016/j.abb.2011.12.017  1
2012 Denisov IG, Shih AY, Sligar SG. Structural differences between soluble and membrane bound cytochrome P450s. Journal of Inorganic Biochemistry. 108: 150-8. PMID 22244217 DOI: 10.1016/j.jinorgbio.2011.11.026  1
2012 Näsvik Öjemyr L, von Ballmoos C, Gennis RB, Sligar SG, Brzezinski P. Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer. Febs Letters. 586: 640-5. PMID 22209982 DOI: 10.1016/j.febslet.2011.12.023  1
2012 Marty MT, Das A, Sligar SG. Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs. Analytical and Bioanalytical Chemistry. 402: 721-9. PMID 22057720 DOI: 10.1007/s00216-011-5512-3  1
2011 Goldsmith BR, Mitala JJ, Josue J, Castro A, Lerner MB, Bayburt TH, Khamis SM, Jones RA, Brand JG, Sligar SG, Luetje CW, Gelperin A, Rhodes PA, Discher BM, Johnson AT. Biomimetic chemical sensors using nanoelectronic readout of olfactory receptor proteins. Acs Nano. 5: 5408-16. PMID 21696137 DOI: 10.1021/nn200489j  1
2011 Luthra A, Denisov IG, Sligar SG. Temperature derivative spectroscopy to monitor the autoxidation decay of cytochromes P450. Analytical Chemistry. 83: 5394-9. PMID 21615185 DOI: 10.1021/ac2009349  1
2011 Karunakaran V, Denisov I, Sligar SG, Champion PM. Investigation of the low frequency dynamics of heme proteins: native and mutant cytochrome P450(cam) and redox partner complexes. The Journal of Physical Chemistry. B. 115: 5665-77. PMID 21391540 DOI: 10.1021/jp112298y  1
2011 Mak PJ, Denisov IG, Grinkova YV, Sligar SG, Kincaid JR. Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. Journal of the American Chemical Society. 133: 1357-66. PMID 21207936 DOI: 10.1021/ja105869p  1
2011 Frank DJ, Denisov IG, Sligar SG. Analysis of heterotropic cooperativity in cytochrome P450 3A4 using alpha-naphthoflavone and testosterone. The Journal of Biological Chemistry. 286: 5540-5. PMID 21177853 DOI: 10.1074/jbc.M110.182055  1
2011 Luthra A, Denisov IG, Sligar SG. Spectroscopic features of cytochrome P450 reaction intermediates. Archives of Biochemistry and Biophysics. 507: 26-35. PMID 21167809 DOI: 10.1016/j.abb.2010.12.008  1
2011 Bayburt TH, Vishnivetskiy SA, McLean MA, Morizumi T, Huang CC, Tesmer JJ, Ernst OP, Sligar SG, Gurevich VV. Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding. The Journal of Biological Chemistry. 286: 1420-8. PMID 20966068 DOI: 10.1074/jbc.M110.151043  1
2011 Denisov IG, Sligar SG. Cytochromes P450 in nanodiscs. Biochimica Et Biophysica Acta. 1814: 223-9. PMID 20685623 DOI: 10.1016/j.bbapap.2010.05.017  1
2011 De La Rama LP, Hu L, Efremov MY, Olson EA, Nealey PF, McLean MA, Sligar SG, Allen LH. Anomalous transitions of DODAB using fast scanning liquid calorimetry Thermochimica Acta. 522: 72-76. DOI: 10.1016/j.tca.2011.05.033  1
2011 Boghossian AA, Choi JH, Ham MH, Jeng ES, Graff RA, Heller DA, Chang AC, Mattis A, Bayburt TH, Grinkova YV, Zeiger AS, Van Vliet KJ, Hobbie EK, Sligar SG, Wraight CA, et al. Photoelectrochemical complexes for solar energy conversion that dynamically, reversibly and autonomously self-assemble 11aiche - 2011 Aiche Annual Meeting, Conference Proceedings 1
2010 Sligar SG. Chemistry. Glimpsing the critical intermediate in cytochrome P450 oxidations. Science (New York, N.Y.). 330: 924-5. PMID 21071657 DOI: 10.1126/science.1197881  1
2010 Ham MH, Choi JH, Boghossian AA, Jeng ES, Graff RA, Heller DA, Chang AC, Mattis A, Bayburt TH, Grinkova YV, Zeiger AS, Van Vliet KJ, Hobbie EK, Sligar SG, Wraight CA, et al. Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate. Nature Chemistry. 2: 929-36. PMID 20966948 DOI: 10.1038/nchem.822  1
2010 Tark SH, Das A, Sligar S, Dravid VP. Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs. Nanotechnology. 21: 435502. PMID 20890017 DOI: 10.1088/0957-4484/21/43/435502  1
2010 Skar-Gislinge N, Simonsen JB, Mortensen K, Feidenhans'l R, Sligar SG, Lindberg Møller B, Bjørnholm T, Arleth L. Elliptical structure of phospholipid bilayer nanodiscs encapsulated by scaffold proteins: casting the roles of the lipids and the protein. Journal of the American Chemical Society. 132: 13713-22. PMID 20828154 DOI: 10.1021/ja1030613  1
2010 Grinkova YV, Denisov IG, Sligar SG. Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers. Protein Engineering, Design & Selection : Peds. 23: 843-8. PMID 20817758 DOI: 10.1093/protein/gzq060  1
2010 Kijac A, Shih AY, Nieuwkoop AJ, Schulten K, Sligar SG, Rienstra CM. Lipid-protein correlations in nanoscale phospholipid bilayers determined by solid-state nuclear magnetic resonance. Biochemistry. 49: 9190-8. PMID 20804175 DOI: 10.1021/bi1013722  1
2010 Früh V, Zhou Y, Chen D, Loch C, Ab E, Grinkova YN, Verheij H, Sligar SG, Bushweller JH, Siegal G. Application of fragment-based drug discovery to membrane proteins: identification of ligands of the integral membrane enzyme DsbB. Chemistry & Biology. 17: 881-91. PMID 20797617 DOI: 10.1016/j.chembiol.2010.06.011  1
2010 Grashoff C, Hoffman BD, Brenner MD, Zhou R, Parsons M, Yang MT, McLean MA, Sligar SG, Chen CS, Ha T, Schwartz MA. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature. 466: 263-6. PMID 20613844 DOI: 10.1038/nature09198  1
2010 Grinkova YV, Denisov IG, Sligar SG. Functional reconstitution of monomeric CYP3A4 with multiple cytochrome P450 reductase molecules in Nanodiscs. Biochemical and Biophysical Research Communications. 398: 194-8. PMID 20599740 DOI: 10.1016/j.bbrc.2010.06.058  1
2010 Ye F, Hu G, Taylor D, Ratnikov B, Bobkov AA, McLean MA, Sligar SG, Taylor KA, Ginsberg MH. Recreation of the terminal events in physiological integrin activation. The Journal of Cell Biology. 188: 157-73. PMID 20048261 DOI: 10.1083/jcb.200908045  1
2010 Davydov DR, Sineva EV, Sistla S, Davydova NY, Frank DJ, Sligar SG, Halpert JR. Electron transfer in the complex of membrane-bound human cytochrome P450 3A4 with the flavin domain of P450BM-3: the effect of oligomerization of the heme protein and intermittent modulation of the spin equilibrium. Biochimica Et Biophysica Acta. 1797: 378-90. PMID 20026040 DOI: 10.1016/j.bbabio.2009.12.008  1
2010 Bayburt TH, Sligar SG. Membrane protein assembly into Nanodiscs. Febs Letters. 584: 1721-7. PMID 19836392 DOI: 10.1016/j.febslet.2009.10.024  1
2010 Mak PJ, Kincaid JR, Denisov IG, Sligar SG, Zhang H, Hollenberg PF. Resonance Raman studies on mammalian cytochromes P450 Aip Conference Proceedings. 1267: 890-891. DOI: 10.1063/1.3482873  1
2009 Das A, Sligar SG. Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer. Biochemistry. 48: 12104-12. PMID 19908820 DOI: 10.1021/bi9011435  1
2009 Ritchie TK, Grinkova YV, Bayburt TH, Denisov IG, Zolnerciks JK, Atkins WM, Sligar SG. Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Methods in Enzymology. 464: 211-31. PMID 19903557 DOI: 10.1016/S0076-6879(09)64011-8  1
2009 Morrissey JH, Pureza V, Davis-Harrison RL, Sligar SG, Rienstra CM, Kijac AZ, Ohkubo YZ, Tajkhorshid E. Protein-membrane interactions: blood clotting on nanoscale bilayers. Journal of Thrombosis and Haemostasis : Jth. 7: 169-72. PMID 19630793 DOI: 10.1111/j.1538-7836.2009.03390.x  1
2009 Gantt SL, Denisov IG, Grinkova YV, Sligar SG. The critical iron-oxygen intermediate in human aromatase. Biochemical and Biophysical Research Communications. 387: 169-73. PMID 19591804 DOI: 10.1016/j.bbrc.2009.06.154  1
2009 Shih AY, Sligar SG, Schulten K. Maturation of high-density lipoproteins. Journal of the Royal Society, Interface / the Royal Society. 6: 863-71. PMID 19570799 DOI: 10.1098/rsif.2009.0173  1
2009 Frank DJ, Denisov IG, Sligar SG. Mixing apples and oranges: Analysis of heterotropic cooperativity in cytochrome P450 3A4. Archives of Biochemistry and Biophysics. 488: 146-52. PMID 19560436 DOI: 10.1016/j.abb.2009.06.013  1
2009 Denisov IG, Frank DJ, Sligar SG. Cooperative properties of cytochromes P450. Pharmacology & Therapeutics. 124: 151-67. PMID 19555717 DOI: 10.1016/j.pharmthera.2009.05.011  1
2009 Das A, Zhao J, Schatz GC, Sligar SG, Van Duyne RP. Screening of type I and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy. Analytical Chemistry. 81: 3754-9. PMID 19364136 DOI: 10.1021/ac802612z  1
2009 McLean MA, Rajfur Z, Chen Z, Humphrey D, Yang B, Sligar SG, Jacobson K. Mechanism of chromophore assisted laser inactivation employing fluorescent proteins. Analytical Chemistry. 81: 1755-61. PMID 19199572 DOI: 10.1021/ac801663y  1
2009 Strano M, Choi JH, Ham MH, Boghossian AA, Jeng ES, Graff RA, Heller DA, Chang AC, Mattis A, Bayburt TH, Grinkova YV, Zeiger AS, Van Vliet KJ, Hobbie EK, Sligar SG, et al. Synthetic photoelectrochemical complexes for solar energy conversion that self-regenerate Conference Proceedings - 2009 Aiche Annual Meeting, 09aiche 0.68
2008 Li H, Das A, Sibhatu H, Jamal J, Sligar SG, Poulos TL. Exploring the electron transfer properties of neuronal nitric-oxide synthase by reversal of the FMN redox potential. The Journal of Biological Chemistry. 283: 34762-72. PMID 18852262 DOI: 10.1074/jbc.M806949200  1
2008 Goluch ED, Shaw AW, Sligar SG, Liu C. Microfluidic patterning of nanodisc lipid bilayers and multiplexed analysis of protein interaction. Lab On a Chip. 8: 1723-8. PMID 18813396 DOI: 10.1039/b806733c  1
2008 Morrissey JH, Pureza V, Davis-Harrison RL, Sligar SG, Ohkubo YZ, Tajkhorshid E. Blood clotting reactions on nanoscale phospholipid bilayers. Thrombosis Research. 122: S23-6. PMID 18691494 DOI: 10.1016/S0049-3848(08)70014-8  1
2008 Denisov IG, Mak PJ, Makris TM, Sligar SG, Kincaid JR. Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450. The Journal of Physical Chemistry. A. 112: 13172-9. PMID 18630867 DOI: 10.1021/jp8017875  1
2008 Borch J, Torta F, Sligar SG, Roepstorff P. Nanodiscs for immobilization of lipid bilayers and membrane receptors: kinetic analysis of cholera toxin binding to a glycolipid receptor. Analytical Chemistry. 80: 6245-52. PMID 18616345 DOI: 10.1021/ac8000644  1
2008 Kühnel K, Ke N, Cryle MJ, Sligar SG, Schuler MA, Schlichting I. Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. Biochemistry. 47: 6552-9. PMID 18512957 DOI: 10.1021/bi800328s  1
2008 Grinkova YV, Denisov IG, Waterman MR, Arase M, Kagawa N, Sligar SG. The ferrous-oxy complex of human aromatase. Biochemical and Biophysical Research Communications. 372: 379-82. PMID 18482580 DOI: 10.1016/j.bbrc.2008.05.011  1
2008 Gruia F, Ionascu D, Kubo M, Ye X, Dawson J, Osborne RL, Sligar SG, Denisov I, Das A, Poulos TL, Terner J, Champion PM. Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy. Biochemistry. 47: 5156-67. PMID 18407660 DOI: 10.1021/bi7025485  1
2008 Shih AY, Sligar SG, Schulten K. Molecular models need to be tested: the case of a solar flares discoidal HDL model. Biophysical Journal. 94: L87-9. PMID 18375520 DOI: 10.1529/biophysj.108.131581  1
2008 Newcomb M, Halgrimson JA, Horner JH, Wasinger EC, Chen LX, Sligar SG. X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative. Proceedings of the National Academy of Sciences of the United States of America. 105: 8179-84. PMID 18174331 DOI: 10.1073/pnas.0708299105  1
2008 Hall B, McLean MA, Davis K, Casanova JE, Sligar SG, Schwartz MA. A fluorescence resonance energy transfer activation sensor for Arf6. Analytical Biochemistry. 374: 243-9. PMID 18162163 DOI: 10.1016/j.ab.2007.11.032  1
2008 Zhao J, Das A, Schatz GC, Sligar SG, Van Duyne RP. Resonance localized surface plasmon spectroscopy: Sensing substrate and inhibitor binding to cytochrome P450 Journal of Physical Chemistry C. 112: 13084-13088. DOI: 10.1021/jp801719c  1
2008 Gruia F, Ionascu D, Kubo M, Ye X, Dawson J, Osborne RL, Sligar SG, Denisov I, Das A, Poulos TL, Terner J, Champion PM. Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy (Biochemistry (2008) 47, 18, (5156-5167)) Biochemistry. 47: 9344. DOI: 10.1021/bi801317z  1
2008 Shih AY, Freddolino PL, Arkhipov A, Sligar SG, Schulten K. Chapter 11 Molecular Modeling of the Structural Properties and Formation of High-Density Lipoprotein Particles Current Topics in Membranes. 60: 313-342. DOI: 10.1016/S1063-5823(08)00011-2  1
2007 Denisov IG, Victoria DC, Sligar SG. Cryoradiolytic reduction of heme proteins: Maximizing dose dependent yield. Radiation Physics and Chemistry (Oxford, England : 1993). 76: 714-721. PMID 18379640 DOI: 10.1016/j.radphyschem.2006.03.002  1
2007 Makris TM, von Koenig K, Schlichting I, Sligar SG. Alteration of P450 distal pocket solvent leads to impaired proton delivery and changes in heme geometry. Biochemistry. 46: 14129-40. PMID 18001135 DOI: 10.1021/bi7013695  1
2007 Kijac AZ, Li Y, Sligar SG, Rienstra CM. Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4. Biochemistry. 46: 13696-703. PMID 17985934 DOI: 10.1021/bi701411g  1
2007 Das A, Grinkova YV, Sligar SG. Redox potential control by drug binding to cytochrome P450 3A4. Journal of the American Chemical Society. 129: 13778-9. PMID 17948999 DOI: 10.1021/ja074864x  1
2007 Marin VL, Bayburt TH, Sligar SG, Mrksich M. Functional assays of membrane-bound proteins with SAMDI-TOF mass spectrometry. Angewandte Chemie (International Ed. in English). 46: 8796-8. PMID 17943935 DOI: 10.1002/anie.200702694  1
2007 Denisov IG, Dawson JH, Hager LP, Sligar SG. The ferric-hydroperoxo complex of chloroperoxidase. Biochemical and Biophysical Research Communications. 363: 954-8. PMID 17920039 DOI: 10.1016/j.bbrc.2007.09.085  1
2007 Sligar SG, Denisov IG. Understanding cooperativity in human p450 mediated drug-drug interactions. Drug Metabolism Reviews. 39: 567-79. PMID 17786639 DOI: 10.1080/03602530701498521  1
2007 Shih AY, Arkhipov A, Freddolino PL, Sligar SG, Schulten K. Assembly of lipids and proteins into lipoprotein particles. The Journal of Physical Chemistry. B. 111: 11095-104. PMID 17696388 DOI: 10.1021/jp072320b  1
2007 Denisov IG, Grinkova YV, McLean MA, Sligar SG. The one-electron autoxidation of human cytochrome P450 3A4. The Journal of Biological Chemistry. 282: 26865-73. PMID 17650504 DOI: 10.1074/jbc.M704747200  1
2007 Kimmich N, Das A, Sevrioukova I, Meharenna Y, Sligar SG, Poulos TL. Electron transfer between cytochrome P450cin and its FMN-containing redox partner, cindoxin. The Journal of Biological Chemistry. 282: 27006-11. PMID 17606612 DOI: 10.1074/jbc.M703790200  1
2007 Nath A, Grinkova YV, Sligar SG, Atkins WM. Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes. The Journal of Biological Chemistry. 282: 28309-20. PMID 17573349 DOI: 10.1074/jbc.M703568200  1
2007 Davydov DR, Baas BJ, Sligar SG, Halpert JR. Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: pivotal role of substrate-induced changes in the accessibility and degree of hydration of the heme pocket. Biochemistry. 46: 7852-64. PMID 17555301 DOI: 10.1021/bi602400y  1
2007 Shih AY, Freddolino PL, Sligar SG, Schulten K. Disassembly of nanodiscs with cholate. Nano Letters. 7: 1692-6. PMID 17503871 DOI: 10.1021/nl0706906  1
2007 Zhao Q, Sigalov G, Dimitrov V, Dorvel B, Mirsaidov U, Sligar S, Aksimentiev A, Timp G. Detecting SNPs using a synthetic nanopore Nano Letters. 7: 1680-1685. PMID 17500578 DOI: 10.1021/nl070668c  1
2007 Mak PJ, Denisov IG, Victoria D, Makris TM, Deng T, Sligar SG, Kincaid JR. Resonance Raman detection of the hydroperoxo intermediate in the cytochrome P450 enzymatic cycle. Journal of the American Chemical Society. 129: 6382-3. PMID 17461587 DOI: 10.1021/ja071426h  1
2007 Alami M, Dalal K, Lelj-Garolla B, Sligar SG, Duong F. Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA. The Embo Journal. 26: 1995-2004. PMID 17396152 DOI: 10.1038/sj.emboj.7601661  1
2007 Bayburt TH, Leitz AJ, Xie G, Oprian DD, Sligar SG. Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins. The Journal of Biological Chemistry. 282: 14875-81. PMID 17395586 DOI: 10.1074/jbc.M701433200  1
2007 Chougnet A, Grinkova Y, Ricard D, Sligar S, Woggon WD. Fluorescent probes for rapid screening of potential drug-drug interactions at the CYP3A4 level Chemmedchem. 2: 717-724. PMID 17357170 DOI: 10.1002/cmdc.200600300  1
2007 Nath A, Atkins WM, Sligar SG. Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins. Biochemistry. 46: 2059-69. PMID 17263563 DOI: 10.1021/bi602371n  1
2007 Denisov IG, Baas BJ, Grinkova YV, Sligar SG. Cooperativity in cytochrome P450 3A4: linkages in substrate binding, spin state, uncoupling, and product formation. The Journal of Biological Chemistry. 282: 7066-76. PMID 17213193 DOI: 10.1074/jbc.M609589200  1
2007 Shaw AW, Pureza VS, Sligar SG, Morrissey JH. The local phospholipid environment modulates the activation of blood clotting. The Journal of Biological Chemistry. 282: 6556-63. PMID 17200119 DOI: 10.1074/jbc.M607973200  1
2007 Schuler MA, Sligar SG. Diversities and similarities in P450 systems: An introduction Metal Ions in Life Sciences. 3: 1-26.  1
2006 Zhao J, Das A, Zhang X, Schatz GC, Sligar SG, Van Duyne RP. Resonance surface plasmon spectroscopy: low molecular weight substrate binding to cytochrome p450. Journal of the American Chemical Society. 128: 11004-5. PMID 16925400 DOI: 10.1021/ja0636082  1
2006 Li Y, Kijac AZ, Sligar SG, Rienstra CM. Structural analysis of nanoscale self-assembled discoidal lipid bilayers by solid-state NMR spectroscopy. Biophysical Journal. 91: 3819-28. PMID 16905610 DOI: 10.1529/biophysj.106.087072  1
2006 Boldog T, Grimme S, Li M, Sligar SG, Hazelbauer GL. Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties. Proceedings of the National Academy of Sciences of the United States of America. 103: 11509-14. PMID 16864771 DOI: 10.1073/pnas.0604988103  1
2006 Denisov IG, Grinkova YV, Baas BJ, Sligar SG. The ferrous-dioxygen intermediate in human cytochrome P450 3A4. Substrate dependence of formation and decay kinetics. The Journal of Biological Chemistry. 281: 23313-8. PMID 16762915 DOI: 10.1074/jbc.M605511200  1
2006 Leitz AJ, Bayburt TH, Barnakov AN, Springer BA, Sligar SG. Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology. Biotechniques. 40: 601-2, 604, 606, pas. PMID 16708760 DOI: 10.2144/000112169  1
2006 Bayburt TH, Grinkova YV, Sligar SG. Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs. Archives of Biochemistry and Biophysics. 450: 215-22. PMID 16620766 DOI: 10.1016/j.abb.2006.03.013  1
2006 Newcomb M, Zhang R, Chandrasena RE, Halgrimson JA, Horner JH, Makris TM, Sligar SG. Cytochrome p450 compound I. Journal of the American Chemical Society. 128: 4580-1. PMID 16594688 DOI: 10.1021/ja060048y  1
2006 Makris TM, von Koenig K, Schlichting I, Sligar SG. The status of high-valent metal oxo complexes in the P450 cytochromes. Journal of Inorganic Biochemistry. 100: 507-18. PMID 16510191 DOI: 10.1016/j.jinorgbio.2006.01.025  1
2005 Denisov IG, McLean MA, Shaw AW, Grinkova YV, Sligar SG. Thermotropic phase transition in soluble nanoscale lipid bilayers. The Journal of Physical Chemistry. B. 109: 15580-8. PMID 16852976 DOI: 10.1021/jp051385g  1
2005 Davydov DR, Fernando H, Baas BJ, Sligar SG, Halpert JR. Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization. Biochemistry. 44: 13902-13. PMID 16229479 DOI: 10.1021/bi0509346  1
2005 Sligar SG, Makris TM, Denisov IG. Thirty years of microbial P450 monooxygenase research: peroxo-heme intermediates--the central bus station in heme oxygenase catalysis. Biochemical and Biophysical Research Communications. 338: 346-54. PMID 16139790 DOI: 10.1016/j.bbrc.2005.08.094  1
2005 Denisov IG, Makris TM, Sligar SG, Schlichting I. Structure and chemistry of cytochrome P450. Chemical Reviews. 105: 2253-77. PMID 15941214 DOI: 10.1021/cr0307143  1
2005 Ke N, Baudry J, Makris TM, Schuler MA, Sligar SG. A retinoic acid binding cytochrome P450: CYP120A1 from Synechocystis sp. PCC 6803. Archives of Biochemistry and Biophysics. 436: 110-20. PMID 15752715 DOI: 10.1016/j.abb.2005.01.011  1
2005 Sono M, Perera R, Jin S, Makris TM, Sligar SG, Bryson TA, Dawson JH. The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM. Archives of Biochemistry and Biophysics. 436: 40-9. PMID 15752707 DOI: 10.1016/j.abb.2004.12.026  1
2005 Shih AY, Denisov IG, Phillips JC, Sligar SG, Schulten K. Molecular dynamics simulations of discoidal bilayers assembled from truncated human lipoproteins. Biophysical Journal. 88: 548-56. PMID 15533924 DOI: 10.1529/biophysj.104.046896  0.76
2005 Makris TM, Denisov I, Schlichting I, Sligar SG. Activation of molecular oxygen by cytochrome P450 Cytochrome P450: Structure, Mechanism, and Biochemistry: Third Edition. 149-182. DOI: 10.1007/0-387-27447-2_5  1
2004 Baas BJ, Denisov IG, Sligar SG. Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment. Archives of Biochemistry and Biophysics. 430: 218-28. PMID 15369821 DOI: 10.1016/j.abb.2004.07.003  1
2004 Duan H, Civjan NR, Sligar SG, Schuler MA. Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers. Archives of Biochemistry and Biophysics. 424: 141-53. PMID 15047186 DOI: 10.1016/j.abb.2004.02.010  1
2004 Denisov IG, Grinkova YV, Lazarides AA, Sligar SG. Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size. Journal of the American Chemical Society. 126: 3477-87. PMID 15025475 DOI: 10.1021/ja0393574  1
2004 Shaw AW, McLean MA, Sligar SG. Phospholipid phase transitions in homogeneous nanometer scale bilayer discs. Febs Letters. 556: 260-4. PMID 14706860 DOI: 10.1016/S0014-5793(03)01400-5  1
2004 Schünemann V, Lendzian F, Jung C, Contzen J, Barra AL, Sligar SG, Trautwein AX. Tyrosine radical formation in the reaction of wild type and mutant cytochrome P450cam with peroxy acids: a multifrequency EPR study of intermediates on the millisecond time scale. The Journal of Biological Chemistry. 279: 10919-30. PMID 14688245 DOI: 10.1074/jbc.M307884200  1
2003 Sligar SG. Finding a single-molecule solution for membrane proteins. Biochemical and Biophysical Research Communications. 312: 115-9. PMID 14630028 DOI: 10.1016/j.bbrc.2003.09.188  1
2003 Coon MJ, Sligar SG. Irwin C. Gunsalus, versatile and creative scientist. Biochemical and Biophysical Research Communications. 312: 1-6, 9-27. PMID 14630011 DOI: 10.1016/S0006-291X(03)02313-1  1
2003 Ibrahim M, Denisov IG, Makris TM, Kincaid JR, Sligar SG. Resonance Raman spectroscopic studies of hydroperoxo-myoglobin at cryogenic temperatures. Journal of the American Chemical Society. 125: 13714-8. PMID 14599210 DOI: 10.1021/ja036949d  1
2003 Bayburt TH, Sligar SG. Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers. Protein Science : a Publication of the Protein Society. 12: 2476-81. PMID 14573860 DOI: 10.1110/ps.03267503  1
2003 Civjan NR, Bayburt TH, Schuler MA, Sligar SG. Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers. Biotechniques. 35: 556-60, 562-3. PMID 14513561  1
2003 Huisman G, Sligar SG. Evolution of protein technologies from voodoo to science. Current Opinion in Biotechnology. 14: 357-9. PMID 12943842 DOI: 10.1016/S0958-1669(03)00103-4  1
2003 Makris TM, Denisov IG, Sligar SG. Haem-oxygen reactive intermediates: catalysis by the two-step. Biochemical Society Transactions. 31: 516-9. PMID 12773147 DOI: 10.1042/  1
2003 Jin S, Makris TM, Bryson TA, Sligar SG, Dawson JH. Epoxidation of olefins by hydroperoxo-ferric cytochrome P450. Journal of the American Chemical Society. 125: 3406-7. PMID 12643683 DOI: 10.1021/ja029272n  1
2002 Makris TM, Davydov R, Denisov IG, Hoffman BM, Sligar SG. Mechanistic enzymology of oxygen activation by the cytochromes P450. Drug Metabolism Reviews. 34: 691-708. PMID 12487147 DOI: 10.1081/DMR-120015691  1
2002 Denisov IG, Ikeda-Saito M, Yoshida T, Sligar SG. Cryogenic absorption spectra of hydroperoxo-ferric heme oxygenase, the active intermediate of enzymatic heme oxygenation. Febs Letters. 532: 203-6. PMID 12459490 DOI: 10.1016/S0014-5793(02)03674-8  1
2002 Dmochowski IJ, Dunn AR, Wilker JJ, Crane BR, Green MT, Dawson JH, Sligar SG, Winkler JR, Gray HB. Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism. Methods in Enzymology. 357: 120-33. PMID 12424904 DOI: 10.1016/S0076-6879(02)57672-2  1
2002 Denisov IG, Makris TM, Sligar SG. Cryoradiolysis for the study of P450 reaction intermediates. Methods in Enzymology. 357: 103-15. PMID 12424902 DOI: 10.1016/S0076-6879(02)57670-9  1
2002 Park SY, Yamane K, Adachi S, Shiro Y, Weiss KE, Maves SA, Sligar SG. Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties. Journal of Inorganic Biochemistry. 91: 491-501. PMID 12237217 DOI: 10.1016/S0162-0134(02)00446-4  1
2002 Denisov IG, Makris TM, Sligar SG. Formation and decay of hydroperoxo-ferric heme complex in horseradish peroxidase studied by cryoradiolysis. The Journal of Biological Chemistry. 277: 42706-10. PMID 12215454 DOI: 10.1074/jbc.M207949200  1
2002 Sanders KE, Lo J, Sligar SG. Intersubunit circular permutation of human hemoglobin. Blood. 100: 299-305. PMID 12070040 DOI: 10.1182/blood.V100.1.299  1
2002 Bayburt TH, Sligar SG. Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks. Proceedings of the National Academy of Sciences of the United States of America. 99: 6725-30. PMID 11997441 DOI: 10.1073/pnas.062565599  1
2002 Hui Bon Hoa G, McLean MA, Sligar SG. High pressure, a tool for exploring heme protein active sites. Biochimica Et Biophysica Acta. 1595: 297-308. PMID 11983404 DOI: 10.1016/S0167-4838(01)00352-1  1
2002 Lynch TW, Sligar SG. Experimental and theoretical high pressure strategies for investigating protein-nucleic acid assemblies. Biochimica Et Biophysica Acta. 1595: 277-82. PMID 11983402 DOI: 10.1016/S0167-4838(01)00350-8  1
2002 Kellner DG, Hung SC, Weiss KE, Sligar SG. Kinetic characterization of compound I formation in the thermostable cytochrome P450 CYP119. The Journal of Biological Chemistry. 277: 9641-4. PMID 11799104 DOI: 10.1074/jbc.C100745200  1
2002 Lynch TW, Kosztin D, McLean MA, Schulten K, Sligar SG. Dissecting the molecular origins of specific protein-nucleic acid recognition: hydrostatic pressure and molecular dynamics. Biophysical Journal. 82: 93-8. PMID 11751298 DOI: 10.1016/S0006-3495(02)75376-9  1
2002 Unno M, Christian JF, Sjodin T, Benson DE, Macdonald ID, Sligar SG, Champion PM. Complex formation of cytochrome P450cam with Putidaredoxin. Evidence for protein-specific interactions involving the proximal thiolate ligand. The Journal of Biological Chemistry. 277: 2547-53. PMID 11706033 DOI: 10.1074/jbc.M108917200  1
2002 Bayburt TH, Grinkova YV, Sligar SG. Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins Nano Letters. 2: 853-856. DOI: 10.1021/nl025623k  1
2002 Rosca F, Yonetani T, Champion PM, Kumar ATN, Ionascu D, Ye X, Demidov AA, Sjodin T, Wharton D, Barrick D, Sligar SG. Investigations of anharmonic low-frequency oscillations in heme proteins Journal of Physical Chemistry A. 106: 3540-3552. DOI: 10.1021/jp0129277  1
2002 Lynch TW, McLean MA, Kosztin D, Schulten K, Sligar SG. High pressure gel mobility shift analysis and molecular dynamics: Investigating specific protein-nucleic acid recognition Progress in Biotechnology. 19: 87-94. DOI: 10.1016/S0921-0423(02)80083-1  1
2001 Denisov IG, Hung SC, Weiss KE, McLean MA, Shiro Y, Park SY, Champion PM, Sligar SG. Characterization of the oxygenated intermediate of the thermophilic cytochrome P450 CYP119. Journal of Inorganic Biochemistry. 87: 215-26. PMID 11744059 DOI: 10.1016/S0162-0134(01)00328-2  1
2001 Ivanov YD, Kanaeva IP, Karuzina II, Usanov SA, Hui Bon Hoa G, Sligar SG, Archakov AI. Revelation of ternary complexes between redox partners in cytochrome P450-containing monooxygenase systems by the optical biosensor method. Journal of Inorganic Biochemistry. 87: 175-84. PMID 11744054 DOI: 10.1016/S0162-0134(01)00332-4  1
2001 Davydov R, Makris TM, Kofman V, Werst DE, Sligar SG, Hoffman BM. Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes. Journal of the American Chemical Society. 123: 1403-15. PMID 11456714 DOI: 10.1021/ja003583l  1
2001 Deng T, Macdonald ID, Simianu MC, Sykora M, Kincaid JR, Sligar SG. Hydrogen-bonding interactions in the active sites of cytochrome P450cam and its site-directed mutants. Journal of the American Chemical Society. 123: 269-78. PMID 11456513 DOI: 10.1021/ja001517d  1
2001 Ivanov YD, Kanaeva IP, Karuzina II, Archakov AI, Hoa GH, Sligar SG. Molecular recognition in the p450cam monooxygenase system: direct monitoring of protein-protein interactions by using optical biosensor. Archives of Biochemistry and Biophysics. 391: 255-64. PMID 11437357 DOI: 10.1006/abbi.2001.2405  1
2001 Sjodin T, Christian JF, Macdonald ID, Davydov R, Unno M, Sligar SG, Hoffman BM, Champion PM. Resonance Raman and EPR investigations of the D251N oxycytochrome P450cam/putidaredoxin complex. Biochemistry. 40: 6852-9. PMID 11389599 DOI: 10.1021/bi002510b  1
2001 Maves SA, Sligar SG. Understanding thermostability in cytochrome P450 by combinatorial mutagenesis. Protein Science : a Publication of the Protein Society. 10: 161-8. PMID 11266604 DOI: 10.1110/ps.17601  1
2001 Denisov IG, Makris TM, Sligar SG. Cryotrapped reaction intermediates of cytochrome p450 studied by radiolytic reduction with phosphorus-32. The Journal of Biological Chemistry. 276: 11648-52. PMID 11152470 DOI: 10.1074/jbc.M010219200  1
2000 Shank-Retzlaff ML, Sligar SG. Analyte gradient-surface plasmon resonance: a one-step method for determining kinetic rates and macromolecular binding affinities. Analytical Chemistry. 72: 4212-20. PMID 10994986  1
2000 Park SY, Yamane K, Adachi S, Shiro Y, Weiss KE, Sligar SG. Crystallization and preliminary X-ray diffraction analysis of a cytochrome P450 (CYP119) from Sulfolobus solfataricus. Acta Crystallographica. Section D, Biological Crystallography. 56: 1173-5. PMID 10957637 DOI: 10.1107/S0907444900008234  1
2000 Lynch TW, Sligar SG. Macromolecular hydration changes associated with BamHI binding and catalysis. The Journal of Biological Chemistry. 275: 30561-5. PMID 10878000 DOI: 10.1074/jbc.M000266200  1
2000 Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. The catalytic pathway of cytochrome p450cam at atomic resolution. Science (New York, N.Y.). 287: 1615-22. PMID 10698731 DOI: 10.1126/science.287.5458.1615  1
2000 Bayburt TH, Carlson JW, Sligar SG. Single molecule height measurements on a membrane protein in nanometer-scale phospholipid bilayer disks Langmuir. 16: 5993-5997. DOI: 10.1021/la991449c  1
2000 Carlson JW, Bayburt T, Sligar SG. Nanopatterning phospholipid bilayers Langmuir. 16: 3927-3931. DOI: 10.1021/la990860x  1
1999 Sligar SG. Nature's universal oxygenases: the cytochromes P450. Essays in Biochemistry. 34: 71-83. PMID 10730189  1
1999 Deng TJ, Proniewicz LM, Kincaid JR, Yeom H, Macdonald ID, Sligar SG. Resonance Raman studies of cytochrome P450BM3 and its complexes with exogenous ligands. Biochemistry. 38: 13699-706. PMID 10521277 DOI: 10.1021/bi991287j  1
1999 Müller JD, McMahon BH, Chien EY, Sligar SG, Nienhaus GU. Connection between the taxonomic substates and protonation of histidines 64 and 97 in carbonmonoxy myoglobin. Biophysical Journal. 77: 1036-51. PMID 10423448  1
1999 Carlson JW, Godfrey BJ, Sligar SG. Metal binding colloidal gold particles: A versatile scanning force microscope tip calibrator for fluid imaging Langmuir. 15: 3086-3090. DOI: 10.1021/la980749b  1
1999 Davydov R, Macdonald IDG, Makris TM, Sugar SG, Hoffman BM. EPR and ENDOR of catalytic intermediates in cryoreduced native and mutant oxy-cytochromes P450cam: Mutation-induced changes in the proton delivery system [15] Journal of the American Chemical Society. 121: 10654-10655. DOI: 10.1021/ja9918829  0.4
1999 Macdonald IDG, Sligar SG, Christian JF, Unno M, Champion PM. Identification of the Fe-O-O bending mode in oxycytochrome P450cam by Resonance Raman spectroscopy Journal of the American Chemical Society. 121: 376-380. DOI: 10.1021/ja9810383  1
1998 McLean MA, Maves SA, Weiss KE, Krepich S, Sligar SG. Characterization of a cytochrome P450 from the acidothermophilic archaea Sulfolobus solfataricus. Biochemical and Biophysical Research Communications. 252: 166-72. PMID 9813164 DOI: 10.1006/bbrc.1998.9584  1
1998 Shank-Retzlaff ML, Raner GM, Coon MJ, Sligar SG. Membrane topology of cytochrome P450 2B4 in Langmuir-Blodgett monolayers. Archives of Biochemistry and Biophysics. 359: 82-8. PMID 9799564 DOI: 10.1006/abbi.1998.0889  1
1998 Bayburt TH, Carlson JW, Sligar SG. Reconstitution and imaging of a membrane protein in a nanometer-size phospholipid bilayer. Journal of Structural Biology. 123: 37-44. PMID 9774543 DOI: 10.1006/jsbi.1998.4007  1
1998 McLean MA, Di Primo C, Deprez E, Hoa GH, Sligar SG. Photoacoustic calorimetry of proteins. Methods in Enzymology. 295: 316-30. PMID 9750225 DOI: 10.1016/S0076-6879(98)95046-7  1
1998 Peterson ES, Friedman JM, Chien EY, Sligar SG. Functional implications of the proximal hydrogen-bonding network in myoglobin: a resonance Raman and kinetic study of Leu89, Ser92, His97, and F-helix swap mutants. Biochemistry. 37: 12301-19. PMID 9724545 DOI: 10.1021/bi980752u  1
1998 Vidakovic M, Sligar SG, Li H, Poulos TL. Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect. Biochemistry. 37: 9211-9. PMID 9649301 DOI: 10.1021/bi980189f  1
1998 Wu Y, Chien EY, Sligar SG, La Mar GN. Influence of proximal side mutations on the molecular and electronic structure of cyanomet myoglobin: an 1H NMR study. Biochemistry. 37: 6979-90. PMID 9578585 DOI: 10.1021/bi9728295  1
1998 Robinson CR, Liu Y, O'Brien R, Sligar SG, Sturtevant JM. A differential scanning calorimetric study of the thermal unfolding of apo- and holo-cytochrome b562. Protein Science : a Publication of the Protein Society. 7: 961-5. PMID 9568902 DOI: 10.1002/pro.5560070413  1
1998 Kwiatkowski LD, Hui HL, Wierzba A, Noble RW, Walder RY, Peterson ES, Sligar SG, Sanders KE. Preparation and kinetic characterization of a series of betaW37 variants of human hemoglobin A: evidence for high-affinity T quaternary structures. Biochemistry. 37: 4325-35. PMID 9521753 DOI: 10.1021/bi970866q  1
1998 Robinson CR, Sligar SG. Changes in solvation during DNA binding and cleavage are critical to altered specificity of the EcoRI endonuclease Proceedings of the National Academy of Sciences of the United States of America. 95: 2186-2191. PMID 9482860 DOI: 10.1073/pnas.95.5.2186  1
1997 Robinson CR, Liu Y, Thomson JA, Sturtevant JM, Sligar SG. Energetics of heme binding to native and denatured states of cytochrome b562. Biochemistry. 36: 16141-6. PMID 9405047 DOI: 10.1021/bi971470h  1
1997 Maves SA, Yeom H, McLean MA, Sligar SG. Decreased substrate affinity upon alteration of the substrate-docking region in cytochrome P450(BM-3). Febs Letters. 414: 213-8. PMID 9315688 DOI: 10.1016/S0014-5793(97)00999-X  1
1997 Christian JF, Unno M, Sage JT, Champion PM, Chien E, Sligar SG. Spectroscopic effects of polarity and hydration in the distal heme pocket of deoxymyoglobin. Biochemistry. 36: 11198-204. PMID 9287162 DOI: 10.1021/bi9710075  1
1997 Carlson JW, Jonas A, Sligar SG. Imaging and manipulation of high-density lipoproteins Biophysical Journal. 73: 1184-1189. PMID 9284285  1
1997 Kellner DG, Maves SA, Sligar SG. Engineering cytochrome P450s for bioremediation. Current Opinion in Biotechnology. 8: 274-8. PMID 9206006 DOI: 10.1016/S0958-1669(97)80003-1  1
1997 Benson DE, Suslick KS, Sligar SG. Reduced oxy intermediate observed in D251N cytochrome P450cam. Biochemistry. 36: 5104-7. PMID 9136869 DOI: 10.1021/bi963170q  1
1997 Pearson JG, Montez B, Le H, Oldfield E, Chien EYT, Sligar SG. Assignment and analysis of fluorine nuclear magnetic resonance spectra of 4-fluorotryptophan myoglobins and hemoglobins Biochemistry. 36: 3590-3599. PMID 9132010 DOI: 10.1021/bi961664h  1
1997 Yeom H, Sligar SG. Oxygen activation by cytochrome P450(BM-3): Effects of mutating an active site acidic residue Archives of Biochemistry and Biophysics. 337: 209-216. PMID 9016815 DOI: 10.1006/abbi.1996.9763  1
1997 Di Primo C, Deprez E, Sligar SG, Hui Bon Hoa G. Origin of the photoacoustic signal in cytochrome P-450(cam): Role of the Arg186-Asp251-Lys178 bifurcated salt bridge Biochemistry. 36: 112-118. PMID 8993324 DOI: 10.1021/bi961508a  1
1997 Unno M, Christian JF, Benson DE, Gerber NC, Sligar SG, Champion PM. Resonance Raman investigations of cytochrome P450(cam) complexed with putidaredoxin Journal of the American Chemical Society. 119: 6614-6620. DOI: 10.1021/ja963785a  1
1997 Benson DF, Snslick KS, Sligar SG. Two electron reduced oxygenated intermediate observed in D251N cytochrome P450cam Faseb Journal. 11: A808.  1
1997 Vidakovic MS, Sligar SG. Evidence for change in proton delivery mechanism in D251N cytochrome P450cam mutant Faseb Journal. 11: A807.  1
1997 Carlson JW, Jonas A, Sligar SG. Imaging and manipulation of reconstituted high-density lipoproteins under physiological conditions using atomic force microscopy Faseb Journal. 11: A1264.  1
1997 Rector KD, Rella CW, Hill JR, Kwok AS, Sligar SG, Chien EYT, Dlott DD, Fayer MD. Mutant and wild-type myoglobin-CO protein dynamics: Vibrational echo experiments Journal of Physical Chemistry B. 101: 1468-1475.  1
1996 McLean MA, Yeom H, Sligar SG. Carbon monoxide binding to cytochrome P450(BM-3): Evidence for a substrate-dependent conformational change Biochimie. 78: 700-705. PMID 9010598 DOI: 10.1016/S0300-9084(97)82527-8  1
1996 Blanke SR, Martinis SA, Sligar SG, Hager LP, Rux JJ, Dawson JH. Probing the heme iron coordination structure of alkaline chloroperoxidase. Biochemistry. 35: 14537-43. PMID 8931550 DOI: 10.1021/bi961512m  1
1996 Martinis SA, Blanke SR, Hager LP, Sligar SG, Hoa GH, Rux JJ, Dawson JH. Probing the heme iron coordination structure of pressure-induced cytochrome P420cam. Biochemistry. 35: 14530-6. PMID 8931549 DOI: 10.1021/bi961511u  1
1996 Robinson CR, Sligar SG. Participation of water in Hin recombinase-DNA recognition Protein Science. 5: 2119-2124. PMID 8897613  1
1996 Jung C, Ristau O, Schulze H, Sligar SG. The CO stretching mode infrared spectrum of substrate-free cytochrome P-450cam-CO: The effect of solvent conditions, temperature, and pressure European Journal of Biochemistry. 235: 660-669. PMID 8654415  1
1996 Firestone MA, Shank ML, Sligar SG, Bohn PW. Film architecture in biomolecular assemblies. Effect of linker on the orientation of genetically engineered surface-bound proteins Journal of the American Chemical Society. 118: 9033-9041. DOI: 10.1021/ja961046o  1
1996 Zhu L, Zhong G, Unno M, Sligar SG, Champion PM. Femtosecond coherence spectroscopy of heme proteins Biospectroscopy. 2: 301-309.  1
1996 Scott JR, Fairris JL, McLean M, Wang K, Sligar SG, Durham B, Millett F. Intramolecular electron-transfer reactions of cytochrome b5 covalently bonded to ruthenium(II) polypyridine complexes: Reorganizational energy and pressure effects Inorganica Chimica Acta. 243: 193-200.  1
1995 Durham B, Fairris JL, McLean M, Millett F, Scott JR, Sligar SG, Willie A. Electron transfer from cytochrome b5 to cytochrome c Journal of Bioenergetics and Biomembranes. 27: 331-340. PMID 8847346 DOI: 10.1007/BF02110102  1
1995 Robinson CR, Sligar SG. Hydrostatic and osmotic pressure as tools to study macromolecular recognition Methods in Enzymology. 259: 395-427. PMID 8538464 DOI: 10.1016/0076-6879(95)59054-4  1
1995 Loida PJ, Sligar SG, Paulsen MD, Arnold GE, Ornstein RL. Stereoselective hydroxylation of norcamphor by cytochrome P450cam. Experimental verification of molecular dynamics simulations. The Journal of Biological Chemistry. 270: 5326-30. PMID 7890644 DOI: 10.1074/jbc.270.10.5326  1
1995 Hernan RA, Sligar SG. Tetrameric hemoglobin expressed in Escherichia coli: Evidence of heterogeneous subunit assembly Journal of Biological Chemistry. 270: 26257-26264. PMID 7592833  1
1995 Dumoulin A, Kiger L, Jiang R, Baudin V, Vasseur C, Sligar SG, Marden MC, Pagnier J, Poyart C. Loss of allosteric behaviour in recombinant hemoglobin α2β29r)F8)His→Ala: Restoration upon addition of strong effectors Febs Letters. 374: 39-42. PMID 7589508 DOI: 10.1016/0014-5793(95)01069-Q  1
1995 Yeom H, Sligar SG, Li H, Poulos TL, Fulco AJ. The role of Thr268 in oxygen activation of cytochrome P450BM-3 Biochemistry. 34: 14733-14740. PMID 7578081  1
1995 Mclean MA, Sligar SG. Thermodynamic Characterization of the Interactions between Cytochrome b5 and Cytochrome c Biochemical and Biophysical Research Communications. 215: 316-320. PMID 7575608 DOI: 10.1006/bbrc.1995.2468  1
1994 Rajarathnam K, Qin J, La Mar GN, Chiu ML, Sligar SG. Correlation between the steric bulk of the distal E7 and E11 residues and the tilt of the FeCN unit in cyanometmyoglobin as determined by NMR from the orientation of the magnetic axes in single and double point mutants. Biochemistry. 33: 5493-501. PMID 8180171 DOI: 10.1021/bi00184a018  1
1994 Thériault Y, Pochapsky TC, Dalvit C, Chiu ML, Sligar SG, Wright PE. 1H and 15N resonance assignments and secondary structure of the carbon monoxide complex of sperm whale myoglobin. Journal of Biomolecular Nmr. 4: 491-504. PMID 8075538 DOI: 10.1007/BF00156616  1
1994 Pin S, Alpert B, Cortès R, Ascone I, Chiu ML, Sligar SG. The heme iron coordination complex in His64(E7)Tyr recombinant sperm whale myoglobin. Biochemistry. 33: 11618-23. PMID 7918375 DOI: 10.1021/bi00204a024  1
1994 Feng Y, Sligar SG, Wand AJ. Solution structure of apocytochrome b562 Nature Structural Biology. 1: 30-35. PMID 7656004 DOI: 10.1038/nsb0194-30  1
1993 Rajarathnam K, Qin J, La Mar GN, Chiu ML, Sligar SG. Solution structure determination of the heme cavity in the E7 His-->Val cyano-met myoglobin point mutant based on the 1H NMR detected dipolar field of the iron: evidence for contraction of the heme pocket. Biochemistry. 32: 5670-80. PMID 8504086 DOI: 10.1021/bi00072a024  1
1993 Lee KB, La Mar GN, Mansfield KE, Smith KM, Pochapsky TC, Sligar SG. Interpretation of hyperfine shift patterns in ferricytochromes b5 in terms of angular position of the heme: a sensitive probe for peripheral heme protein interactions. Biochimica Et Biophysica Acta. 1202: 189-99. PMID 8399380 DOI: 10.1016/0167-4838(93)90004-B  1
1993 Willie A, McLean M, Liu RQ, Hilgen-Willis S, Saunders AJ, Pielak GJ, Sligar SG, Durham B, Millett F. Intracomplex electron transfer between ruthenium-65-cytochrome b5 and position-82 variants of yeast iso-1-cytochrome c. Biochemistry. 32: 7519-25. PMID 8393343 DOI: 10.1021/bi00080a025  1
1993 Ropp JD, Gunsalus IC, Sligar SG. Cloning and expression of a member of a new cytochrome P-450 family: cytochrome P-450lin (CYP111) from Pseudomonas incognita. Journal of Bacteriology. 175: 6028-37. PMID 8376348 DOI: 10.1128/jb.175.18.6028-6037.1993  1
1993 Braunstein DP, Chu K, Egeberg KD, Frauenfelder H, Mourant JR, Nienhaus GU, Ormos P, Sligar SG, Springer BA, Young RD. Ligand binding to heme proteins: III. FTIR studies of His-E7 and Val-E11 mutants of carbonmonoxymyoglobin. Biophysical Journal. 65: 2447-54. PMID 8312483 DOI: 10.1016/S0006-3495(93)81310-9  1
1993 Koch T, Ropp JD, Sligar SG, Schuster GB. Photocleavage of DNA: irradiation of quinone-containing reagents converts supercoiled to linear DNA. Photochemistry and Photobiology. 58: 554-8. PMID 8248331 DOI: 10.1111/j.1751-1097.1993.tb04931.x  1
1993 McLean MA, Stayton PS, Sligar SG. Engineering protein orientation at surfaces to control macromolecular recognition events Analytical Chemistry. 65: 2676-2678. PMID 8238945 DOI: 10.1021/ac00067a021  1
1993 Cortes R, Ascone I, Pin S, Alpert B, Chiu ML, Sligar SG. Xas study of the heme iron coordination in his64(E7)tyr synthetic sperm whale myoglobin Japanese Journal of Applied Physics. 32: 544-546. DOI: 10.7567/JJAPS.32S2.544  1
1992 Wells AV, Li P, Champion PM, Martinis SA, Sligar SG. Resonance Raman investigations of Escherichia coli-expressed Pseudomonas putida cytochrome P450 and P420 Biochemistry. 31: 4384-4393. PMID 1581294 DOI: 10.1021/bi00133a002  1
1992 Van Dyke BR, Bakan DA, Glover KAM, Hegenauer JC, Saltman P, Springer BA, Sligar SG. Site-directed mutagenesis of histidine residues involved in Cu(II) binding and reduction by sperm whale myoglobin Proceedings of the National Academy of Sciences of the United States of America. 89: 8016-8019. PMID 1518828 DOI: 10.1073/pnas.89.17.8016  1
1992 Bormett RW, Asher SA, Larking PJ, Gustafson WG, Ragunathan N, Freedman TB, Nafie LA, Balasubramanian S, Boxer SG, Yu NT, Genonde K, Noble RW, Springer BA, Sligar SG. Selective examination of heme protein azide ligand-distal globin interactions by vibrational circular dichroism Journal of the American Chemical Society. 114: 6864-6867.  1
1991 Carver TE, Olson JS, Smerdon SJ, Krzywda S, Wilkinson AJ, Gibson QH, Blackmore RS, Ropp JD, Sligar SG. Contributions of residue 45(CD3) and heme-6-propionate to the biomolecular and geminate recombination reactions of myoglobin. Biochemistry. 30: 4697-705. PMID 2029516 DOI: 10.1021/bi00233a009  1
1991 Wu JZ, La Mar GN, Yu LP, Lee KB, Walker FA, Chiu ML, Sligar SG. 1H NMR study of the solution molecular and electronic structure of Escherichia coli ferricytochrome b562: evidence for S = 1/2 in equilibrium S = 5/2 spin equilibrium for intact His/Met ligation. Biochemistry. 30: 2156-65. PMID 1998676 DOI: 10.1021/bi00222a020  1
1991 Sligar SG, Filipovic D, Stayton PS. Mutagenesis of cytochromes P450cam and b5 Methods in Enzymology. 206: 31-49. PMID 1784217 DOI: 10.1016/0076-6879(91)06074-D  1
1991 Frauenfelder H, Sligar SG, Wolynes PG. The energy landscapes and motions of proteins. Science (New York, N.Y.). 254: 1598-603. PMID 1749933 DOI: 10.1126/science.1749933  1
1991 Raag R, Martinis SA, Sligar SG, Poulos TL. Crystal structure of the cytochrome P-450(CAM) active site mutant Thr252Ala Biochemistry. 30: 11420-11429. PMID 1742281 DOI: 10.1021/bi00112a008  0.4
1990 Lee KB, La Mar GN, Kehres LA, Fujinari EM, Smith KM, Pochapsky TC, Sligar SG. 1H NMR study of the influence of hydrophobic contacts on protein-prosthetic group recognition in bovine and rat ferricytochrome b5. Biochemistry. 29: 9623-31. PMID 2271605 DOI: 10.1021/bi00493a017  1
1990 Stayton PS, Sligar SG. The cytochrome p-450cam binding surface as defined by site-directed mutagenesis and electrostatic modeling Biochemistry®. 29: 7381-7386. PMID 2223769 DOI: 10.1021/bi00484a005  1
1990 Phillips GN, Arduini RM, Springer BA, Sligar SG. Crystal structure of myoglobin from a synthetic gene Proteins: Structure, Function and Genetics. 7: 358-365. PMID 2199973 DOI: 10.1002/prot.340070407  1
1990 Egeberg KD, Springer BA, Martinis SA, Sligar SG, Morikis D, Champion PM. Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis Biochemistry. 29: 9783-9791. PMID 2176857 DOI: 10.1021/bi00494a004  1
1990 Westrick JA, Peters KS, Dezz Ropp J, Sligar SG. Role of the arginine-45 salt bridge in ligand dissociation from sperm whale carboxymyoglobin as probed by photoacoustic calorimetry Biochemistry®. 29: 6741-6746. PMID 2168740 DOI: 10.1021/bi00480a026  1
1990 Pochapsky TC, Sligar SG, McLachlan SJ, La Mar GN. Relationship between heme binding site structure and heme orientations of two ferrocytochrome b5s. A study in prosthetic group recognition Journal of the American Chemical Society. 112: 5258-5263. DOI: 10.1021/ja00169a038  1
1989 Morikis D, Champion PM, Springer BA, Sligar SG. Resonance Raman investigations of site-directed mutants of myoglobin: Effects of distal histidine replacement Biochemistry. 28: 4791-4800. PMID 2765511 DOI: 10.1021/bi00437a041  1
1989 Stayton PS, Poulos TL, Sligar SG. Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: A proposed molecular model for a cytochrome P-450cam electron-transfer complex Biochemistry. 28: 8201-8205. PMID 2690937 DOI: 10.1021/bi00446a035  1
1989 Hui Bon Hoa G, Di Primo C, Dondaine I, Sligar SG, Gunsalus IC, Douzou P. Conformational changes of cytochromes P-450cam and P-450lin induced by high pressure. Biochemistry. 28: 651-6. PMID 2578028 DOI: 10.1021/bi00428a035  1
1989 Martinis SA, Sotiriou C, Chang CK, Sligar SG. Characterization of cytochrome b5 reconstituted with a ferric chlorin and a ferric oxochlorin Biochemistry. 28: 879-884. PMID 2540809 DOI: 10.1021/bi00428a071  1
1988 Olson JS, Mathews AJ, Rohlfs RJ, Springer BA, Egeberg KD, Sligar SG, Tame J, Renaud JP, Nagai K. The role of the distal histidine in myoglobin and haemoglobin. Nature. 336: 265-6. PMID 3057383 DOI: 10.1038/336265a0  1
1988 Rodgers KK, Pochapsky TC, Sligar SG. Probing the mechanisms of macromolecular recognition: The cytochrome b 5-cytochrome c complex Science. 240: 1657-1659. PMID 2837825 DOI: 10.1126/science.2837825  1
1987 Springer BA, Sligar SG. High-level expression of sperm whale myoglobin in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 84: 8961-8965. PMID 3321062 DOI: 10.1073/pnas.84.24.8961  1
1986 Huang YY, Hara T, Sligar S, Coon MJ, Kimura T. Thermodynamic properties of oxidation-reduction reactions of bacterial, microsomal, and mitochondrial cytochromes P-450: an entropy-enthalpy compensation effect. Biochemistry. 25: 1390-4. PMID 3964682 DOI: 10.1021/bi00354a030  1
1986 Beck von Bodman S, Schuler MA, Jollie DR, Sligar SG. Synthesis, bacterial expression, and mutagenesis of the gene coding for mammalian cytochrome b5 Proceedings of the National Academy of Sciences of the United States of America. 83: 9443-9447. PMID 3540940 DOI: 10.1073/pnas.83.24.9443  1
1985 Fisher MT, Sligar SG. Tyrosine motions in relation to the ferric spin equilibrium of cytochrome P-450cam Biochemistry. 24: 6696-6701. PMID 4084552 DOI: 10.1021/bi00344a059  1
1985 Werneke JM, Sligar SG, Schuler MA. Development of broad-host-range vectors for expression of cloned genes in Pseudomonas Gene. 38: 73-84. PMID 4065575 DOI: 10.1016/0378-1119(85)90205-7  1
1985 Keyes SR, Heimbrook DC, Fracasso PM, Rockwell S, Sligar SG, Sartorelli AC. Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C. Advances in Enzyme Regulation. 23: 291-307. PMID 3934922 DOI: 10.1016/0065-2571(85)90053-6  1
1985 Fisher MT, Scarlata SF, Sligar SG. High-pressure investigations of cytochrome P-450 spin and substrate binding equilibria Archives of Biochemistry and Biophysics. 240: 456-463. PMID 2990349 DOI: 10.1016/0003-9861(85)90050-5  1
1984 Sligar SG, Gelb MH, Heimbrook DC. Bio-organic chemistry and cytochrome P-450-dependent catalysis. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 14: 63-86. PMID 6372267 DOI: 10.3109/00498258409151399  0.84
1982 Gelb MH, Heimbrook DC, Mälkönen P, Sligar SG. Stereochemistry and deuterium isotope effects in camphor hydroxylation by the cytochrome P450cam monoxygenase system. Biochemistry. 21: 370-7. PMID 7074020  0.84
1982 Gelb MH, Malkonen P, Sligar SG. Cytochrome P450cam catalyzed epoxidation of dehydrocamphor. Biochemical and Biophysical Research Communications. 104: 853-8. PMID 7073732  0.84
1982 Gelb MH, Toscano WA, Sligar SG. Chemical mechanisms for cytochrome P-450 oxidation: spectral and catalytic properties of a manganese-substituted protein. Proceedings of the National Academy of Sciences of the United States of America. 79: 5758-62. PMID 6964386  0.84
1982 Kennedy KA, Sligar SG, Polomski L, Sartorelli AC. Metabolic activation of mitomycin C by liver microsomes and nuclei Biochemical Pharmacology. 31: 2011-2016. PMID 6810899 DOI: 10.1016/0006-2952(82)90414-2  1
1981 Gould PV, Gelb MH, Sligar SG. Interaction of 5-bromocamphor with cytochrome P-450 cam. Production of 5-ketocamphor from a mixed spin state hemoprotein. The Journal of Biological Chemistry. 256: 6686-91. PMID 7240237  0.84
1980 Sligar SG, Kennedy KA, Pearson DC. Chemical mechanisms for cytochrome P-450 hydroxylation: Evidence for acylation of heme-bound dioxygen Proceedings of the National Academy of Sciences of the United States of America. 77: 1240-1244. PMID 6929480 DOI: 10.1073/pnas.77.3.1240  1
1980 Henes JB, Briggs MS, Sligar SG, Fruton JS. Fluorescence energy transfer studies on the active site of papain. Proceedings of the National Academy of Sciences of the United States of America. 77: 940-3. PMID 6928689 DOI: 10.1073/pnas.77.2.940  1
1979 Sligar SG, Gunsalus IC. Proton coupling in the cytochrome P-450 spin and redox equilibria. Biochemistry. 18: 2290-5. PMID 444456 DOI: 10.1021/bi00578a024  1
1978 Gunsalus IC, Sligar SG. Oxygen reduction by the P450 monoxygenase systems. Advances in Enzymology and Related Areas of Molecular Biology. 47: 1-44. PMID 364937 DOI: 10.1002/9780470122921.ch1  1
1977 Gunsalus IC, Sligar SG, Nordlund T, Frauenfelder H. Oxygen sensing heme proteins: monoxygenases, myoglobin and hemoglobin. Advances in Experimental Medicine and Biology. 78: 37-50. PMID 331893 DOI: 10.1007/978-1-4615-9035-4_3  1
1976 Sligar SG, Gunsalus IC. A thermodynamic model of regulation: modulation of redox equilibria in camphor monoxygenase. Proceedings of the National Academy of Sciences of the United States of America. 73: 1078-82. PMID 1063390 DOI: 10.1073/pnas.73.4.1078  1
1976 Gunsalus IC, Sligar SG. Redox regulation of cytochrome P450cam mixed function oxidation by putidaredoxin and camphor ligation. Biochimie. 58: 143-7. PMID 953050 DOI: 10.1016/S0300-9084(76)80364-1  1
1976 Gunsalus IC, Sligar SG. Equilibrium states and dynamic reactions of iron in the camphor monoxygenase system. Advances in Experimental Medicine and Biology. 74: 254-62. PMID 785975 DOI: 10.1007/978-1-4684-3270-1_18  1
1975 Gunsalus IC, Pederson TC, Sligar SG. Oxygenase-catalyzed biological hydroxylations. Annual Review of Biochemistry. 44: 377-407. PMID 806252 DOI: 10.1146/annurev.bi.44.070175.002113  1
1974 Sligar SG, Debrunner PG, Lipscomb JD, Namtvedt MJ, Gunsalus IC. A role of the putidaredoxin COOH-terminus in P-450cam (cytochrome m) hydroxylations. Proceedings of the National Academy of Sciences of the United States of America. 71: 3906-10. PMID 4530269 DOI: 10.1073/pnas.71.10.3906  1
1974 Sligar SG, Lipscomb JD, Debrunner PG, Gunsalus IC. Superoxide anion production by the autoxidation of cytochrome P450cam. Biochemical and Biophysical Research Communications. 61: 290-6. PMID 4441397 DOI: 10.1016/0006-291X(74)90565-8  1
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