Dennis A. Dougherty - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 
Area:
physical organic chemistry to systems of biological importance
Website:
http://www.its.caltech.edu/~dadgrp/people/dad.shtml

181 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shivange AV, Borden PM, Muthusamy AK, Nichols AL, Bera K, Bao H, Bishara I, Jeon J, Mulcahy MJ, Cohen B, O'Riordan SL, Kim C, Dougherty DA, Chapman ER, Marvin J, et al. Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. The Journal of General Physiology. PMID 30718376 DOI: 10.1085/jgp.201812201  1
2018 Henderson BJ, Grant S, Chu BW, Shahoei R, Huard SM, Saladi SSM, Tajkhorshid E, Dougherty DA, Lester HA. Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing. Eneuro. 5. PMID 30627659 DOI: 10.1523/ENEURO.0465-18.2018  1
2018 Mosesso R, Dougherty DA, Lummis SCR. Probing Proline Residues in the Prokaryotic Ligand-Gated Ion Channel, ELIC. Biochemistry. PMID 29927250 DOI: 10.1021/acs.biochem.8b00379  0.56
2017 Post MR, Tender GS, Lester HA, Dougherty DA. Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors. Eneuro. 4. PMID 28589175 DOI: 10.1523/ENEURO.0032-17.2017  1
2017 Post M, Lester HA, Dougherty DA. Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors. Biochemistry. PMID 28287260 DOI: 10.1021/acs.biochem.7b00213  1
2016 Nichols WA, Henderson BJ, Marotta CB, Yu CY, Richards C, Dougherty DA, Lester HA, Cohen BN. Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression. Plos One. 11: e0158032. PMID 27336596 DOI: 10.1371/journal.pone.0158032  1
2015 Rienzo M, Rocchi AR, Threatt SD, Dougherty DA, Lummis SC. Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-Gated Ion Channel (GLIC) Supports Conserved Gating Motions Among Cys-Loop Receptors. The Journal of Biological Chemistry. PMID 26668320 DOI: 10.1074/jbc.M115.694372  1
2015 Davis MR, Dougherty DA. Cation-π interactions: computational analyses of the aromatic box motif and the fluorination strategy for experimental evaluation. Physical Chemistry Chemical Physics : Pccp. 17: 29262-70. PMID 26467787 DOI: 10.1039/c5cp04668h  1
2015 Marotta CB, Lester HA, Dougherty DA. An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors. Chemistry & Biology. 22: 1063-73. PMID 26211363 DOI: 10.1016/j.chembiol.2015.06.018  1
2015 Lester HA, Lavis LD, Dougherty DA. Ketamine Inside Neurons? The American Journal of Psychiatry. appiajp201514121537. PMID 26183700 DOI: 10.1176/appi.ajp.2015.14121537  1
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, ... ... Dougherty DA, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/scitranslmed.3009986  1
2015 Post MR, Limapichat W, Lester HA, Dougherty DA. Heterologous expression and nonsense suppression provide insights into agonist behavior at α6β2 nicotinic acetylcholine receptors. Neuropharmacology. 97: 376-382. PMID 25908401 DOI: 10.1016/j.neuropharm.2015.04.009  1
2015 Miles TF, Lester HA, Dougherty DA. Allosteric activation of the 5-HT3AB receptor by mCPBG. Neuropharmacology. 91: 103-8. PMID 25541413 DOI: 10.1016/j.neuropharm.2014.12.018  1
2014 Rienzo M, Lummis SC, Dougherty DA. Structural requirements in the transmembrane domain of GLIC revealed by incorporation of noncanonical histidine analogs. Chemistry & Biology. 21: 1700-6. PMID 25525989 DOI: 10.1016/j.chembiol.2014.10.019  1
2014 Daeffler KN, Lester HA, Dougherty DA. Functional evaluation of key interactions evident in the structure of the eukaryotic Cys-loop receptor GluCl. Acs Chemical Biology. 9: 2283-90. PMID 25051140 DOI: 10.1021/cb500323d  1
2014 Dougherty DA, Van Arnam EB. In vivo incorporation of non-canonical amino acids by using the chemical aminoacylation strategy: a broadly applicable mechanistic tool. Chembiochem : a European Journal of Chemical Biology. 15: 1710-20. PMID 24990307 DOI: 10.1002/cbic.201402080  1
2014 Limapichat W, Dougherty DA, Lester HA. Subtype-specific mechanisms for functional interaction between α6β4* nicotinic acetylcholine receptors and P2X receptors. Molecular Pharmacology. 86: 263-74. PMID 24966348 DOI: 10.1124/mol.114.093179  1
2014 Van Arnam EB, Dougherty DA. Functional probes of drug-receptor interactions implicated by structural studies: Cys-loop receptors provide a fertile testing ground. Journal of Medicinal Chemistry. 57: 6289-300. PMID 24568098 DOI: 10.1021/jm500023m  1
2014 Marotta CB, Rreza I, Lester HA, Dougherty DA. Selective ligand behaviors provide new insights into agonist activation of nicotinic acetylcholine receptors. Acs Chemical Biology. 9: 1153-9. PMID 24564429 DOI: 10.1021/cb400937d  1
2014 Marotta CB, Dilworth CN, Lester HA, Dougherty DA. Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor. Neuropharmacology. 77: 342-9. PMID 24144909 DOI: 10.1016/j.neuropharm.2013.09.028  1
2013 Miles TF, Dougherty DA, Lester HA. The 5-HT3AB receptor shows an A3B2 stoichiometry at the plasma membrane. Biophysical Journal. 105: 887-98. PMID 23972841 DOI: 10.1016/j.bpj.2013.07.015  1
2013 Van Arnam EB, Blythe EE, Lester HA, Dougherty DA. An unusual pattern of ligand-receptor interactions for the α7 nicotinic acetylcholine receptor, with implications for the binding of varenicline. Molecular Pharmacology. 84: 201-7. PMID 23680636 DOI: 10.1124/mol.113.085795  1
2013 Limapichat W, Yu WY, Branigan E, Lester HA, Dougherty DA. Key binding interactions for memantine in the NMDA receptor. Acs Chemical Neuroscience. 4: 255-60. PMID 23421676 DOI: 10.1021/cn300180a  1
2013 Blum AP, Van Arnam EB, German LA, Lester HA, Dougherty DA. Binding interactions with the complementary subunit of nicotinic receptors. The Journal of Biological Chemistry. 288: 6991-7. PMID 23349463 DOI: 10.1074/jbc.M112.439968  1
2013 Dougherty DA. The cation-π interaction. Accounts of Chemical Research. 46: 885-93. PMID 23214924 DOI: 10.1021/ar300265y  1
2012 Ashby JA, McGonigle IV, Price KL, Cohen N, Comitani F, Dougherty DA, Molteni C, Lummis SC. GABA binding to an insect GABA receptor: a molecular dynamics and mutagenesis study. Biophysical Journal. 103: 2071-81. PMID 23200041 DOI: 10.1016/j.bpj.2012.10.016  1
2012 Miles TF, Bower KS, Lester HA, Dougherty DA. A coupled array of noncovalent interactions impacts the function of the 5-HT3A serotonin receptor in an agonist-specific way. Acs Chemical Neuroscience. 3: 753-60. PMID 23077719 DOI: 10.1021/cn3000586  1
2012 Spurny R, Ramerstorfer J, Price K, Brams M, Ernst M, Nury H, Verheij M, Legrand P, Bertrand D, Bertrand S, Dougherty DA, de Esch IJ, Corringer PJ, Sieghart W, Lummis SC, et al. Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proceedings of the National Academy of Sciences of the United States of America. 109: E3028-34. PMID 23035248 DOI: 10.1073/pnas.1208208109  1
2012 Srinivasan R, Richards CI, Dilworth C, Moss FJ, Dougherty DA, Lester HA. Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2. International Journal of Molecular Sciences. 13: 10022-40. PMID 22949846 DOI: 10.3390/ijms130810022  1
2012 Daeffler KN, Lester HA, Dougherty DA. Functionally important aromatic-aromatic and sulfur-π interactions in the D2 dopamine receptor. Journal of the American Chemical Society. 134: 14890-6. PMID 22897614 DOI: 10.1021/ja304560x  1
2012 Duffy NH, Lester HA, Dougherty DA. Ondansetron and granisetron binding orientation in the 5-HT(3) receptor determined by unnatural amino acid mutagenesis. Acs Chemical Biology. 7: 1738-45. PMID 22873819 DOI: 10.1021/cb300246j  1
2012 Tavares Xda S, Blum AP, Nakamura DT, Puskar NL, Shanata JA, Lester HA, Dougherty DA. Variations in binding among several agonists at two stoichiometries of the neuronal, α4β2 nicotinic receptor. Journal of the American Chemical Society. 134: 11474-80. PMID 22716019 DOI: 10.1021/ja3011379  1
2012 Richards CI, Luong K, Srinivasan R, Turner SW, Dougherty DA, Korlach J, Lester HA. Live-cell imaging of single receptor composition using zero-mode waveguide nanostructures. Nano Letters. 12: 3690-4. PMID 22668081 DOI: 10.1021/nl301480h  1
2012 Lummis SC, Harrison NJ, Wang J, Ashby JA, Millen KS, Beene DL, Dougherty DA. Multiple Tyrosine Residues Contribute to GABA Binding in the GABA(C) Receptor Binding Pocket. Acs Chemical Neuroscience. 3: 186-192. PMID 22448304 DOI: 10.1021/cn200103n  1
2012 Srinivasan R, Richards CI, Xiao C, Rhee D, Pantoja R, Dougherty DA, Miwa JM, Lester HA. Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response. Molecular Pharmacology. 81: 759-69. PMID 22379121 DOI: 10.1124/mol.112.077792  1
2012 Puskar NL, Lester HA, Dougherty DA. Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor. Acs Chemical Biology. 7: 841-6. PMID 22296725 DOI: 10.1021/cb200448j  1
2012 Shanata JA, Frazier SJ, Lester HA, Dougherty DA. Using mutant cycle analysis to elucidate long-range functional coupling in allosteric receptors. Methods in Molecular Biology (Clifton, N.J.). 796: 97-113. PMID 22052487 DOI: 10.1007/978-1-61779-334-9_6  1
2011 Lummis SC, McGonigle I, Ashby JA, Dougherty DA. Two amino acid residues contribute to a cation-Ï€ binding interaction in the binding site of an insect GABA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 12371-6. PMID 21865479 DOI: 10.1523/JNEUROSCI.1610-11.2011  1
2011 Van Arnam EB, Lester HA, Dougherty DA. Dissecting the functions of conserved prolines within transmembrane helices of the D2 dopamine receptor. Acs Chemical Biology. 6: 1063-8. PMID 21776983 DOI: 10.1021/cb200153g  1
2011 Blum AP, Gleitsman KR, Lester HA, Dougherty DA. Evidence for an extended hydrogen bond network in the binding site of the nicotinic receptor: role of the vicinal disulfide of the alpha1 subunit. The Journal of Biological Chemistry. 286: 32251-8. PMID 21757705 DOI: 10.1074/jbc.M111.254235  1
2011 Puskar NL, Xiu X, Lester HA, Dougherty DA. Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes. The Journal of Biological Chemistry. 286: 14618-27. PMID 21343288 DOI: 10.1074/jbc.M110.206565  1
2011 Pless SA, Hanek AP, Price KL, Lynch JW, Lester HA, Dougherty DA, Lummis SC. A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists. Molecular Pharmacology. 79: 742-8. PMID 21266487 DOI: 10.1124/mol.110.069583  1
2011 Puskar NL, Xiu X, Lester HA, Dougherty DA. Two neuronal nicotinic acetylcholine receptors, α4β4 and α7, show differential agonist binding modes (Journal of Biological Chemistry (2011) 286, (14618-14627)) Journal of Biological Chemistry. 286: 29442. DOI: 10.1074/jbc.A110.206565  1
2010 Kedrowski SM, Dougherty DA. Room-temperature alternative to the Arbuzov reaction: the reductive deoxygenation of acyl phosphonates. Organic Letters. 12: 3990-3. PMID 20726566 DOI: 10.1021/ol1015493  1
2010 Duffy NH, Dougherty DA. Preparation of translationally competent tRNA by direct chemical acylation. Organic Letters. 12: 3776-9. PMID 20687605 DOI: 10.1021/ol101408f  1
2010 Blum AP, Lester HA, Dougherty DA. Nicotinic pharmacophore: the pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH. Proceedings of the National Academy of Sciences of the United States of America. 107: 13206-11. PMID 20616056 DOI: 10.1073/pnas.1007140107  1
2010 Hanek AP, Lester HA, Dougherty DA. Photochemical proteolysis of an unstructured linker of the GABAAR extracellular domain prevents GABA but not pentobarbital activation. Molecular Pharmacology. 78: 29-35. PMID 20363860 DOI: 10.1124/mol.109.059832  1
2010 Tao X, Lee A, Limapichat W, Dougherty DA, MacKinnon R. A gating charge transfer center in voltage sensors. Science (New York, N.Y.). 328: 67-73. PMID 20360102 DOI: 10.1126/science.1185954  1
2010 Limapichat W, Lester HA, Dougherty DA. Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors. The Journal of Biological Chemistry. 285: 8976-84. PMID 20068044 DOI: 10.1074/jbc.M109.060939  1
2009 Ahern CA, Eastwood AL, Dougherty DA, Horn R. An electrostatic interaction between TEA and an introduced pore aromatic drives spring-in-the-door inactivation in Shaker potassium channels. The Journal of General Physiology. 134: 461-9. PMID 19917730 DOI: 10.1085/jgp.200910260  1
2009 Eastwood AL, Blum AP, Zacharias NM, Dougherty DA. A selenide-based approach to photochemical cleavage of peptide and protein backbones at engineered backbone esters. The Journal of Organic Chemistry. 74: 9241-4. PMID 19902952 DOI: 10.1021/jo901368g  1
2009 Torrice MM, Bower KS, Lester HA, Dougherty DA. Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 106: 11919-24. PMID 19581583 DOI: 10.1073/pnas.0903260106  1
2009 Gleitsman KR, Lester HA, Dougherty DA. Probing the role of backbone hydrogen bonding in a critical beta sheet of the extracellular domain of a cys-loop receptor. Chembiochem : a European Journal of Chemical Biology. 10: 1385-91. PMID 19405066 DOI: 10.1002/cbic.200900092  1
2009 Gleitsman KR, Shanata JA, Frazier SJ, Lester HA, Dougherty DA. Long-range coupling in an allosteric receptor revealed by mutant cycle analysis. Biophysical Journal. 96: 3168-78. PMID 19383461 DOI: 10.1016/j.bpj.2008.12.3949  1
2009 Lester HA, Xiao C, Srinivasan R, Son CD, Miwa J, Pantoja R, Banghart MR, Dougherty DA, Goate AM, Wang JC. Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. The Aaps Journal. 11: 167-77. PMID 19280351 DOI: 10.1208/s12248-009-9090-7  1
2009 Xiu X, Puskar NL, Shanata JA, Lester HA, Dougherty DA. Nicotine binding to brain receptors requires a strong cation-pi interaction. Nature. 458: 534-7. PMID 19252481 DOI: 10.1038/nature07768  1
2009 Pantoja R, Rodriguez EA, Dibas MI, Dougherty DA, Lester HA. Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors. Biophysical Journal. 96: 226-37. PMID 19134478 DOI: 10.1016/j.bpj.2008.09.034  1
2008 Gleitsman KR, Kedrowski SM, Lester HA, Dougherty DA. An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating. The Journal of Biological Chemistry. 283: 35638-43. PMID 18952603 DOI: 10.1074/jbc.M807226200  1
2008 Pless SA, Millen KS, Hanek AP, Lynch JW, Lester HA, Lummis SC, Dougherty DA. A cation-pi interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10937-42. PMID 18945901 DOI: 10.1523/JNEUROSCI.2540-08.2008  1
2008 Hanek AP, Lester HA, Dougherty DA. A stereochemical test of a proposed structural feature of the nicotinic acetylcholine receptor. Journal of the American Chemical Society. 130: 13216-8. PMID 18781739 DOI: 10.1021/ja8015457  1
2008 Ahern CA, Eastwood AL, Dougherty DA, Horn R. New insights into the therapeutic inhibition of voltage-gated sodium channels. Channels (Austin, Tex.). 2: 1-3. PMID 18690056 DOI: 10.4161/chan.2.1.6007  1
2008 Price KL, Bower KS, Thompson AJ, Lester HA, Dougherty DA, Lummis SC. A hydrogen bond in loop A is critical for the binding and function of the 5-HT3 receptor. Biochemistry. 47: 6370-7. PMID 18498149 DOI: 10.1021/bi800222n  1
2008 Dougherty DA. Cys-loop neuroreceptors: structure to the rescue? Chemical Reviews. 108: 1642-53. PMID 18447378 DOI: 10.1021/cr078207z  1
2008 Dougherty DA. Physical organic chemistry on the brain. The Journal of Organic Chemistry. 73: 3667-73. PMID 18412391 DOI: 10.1021/jo8001722  1
2008 Maurer JA, Elmore DE, Clayton D, Xiong L, Lester HA, Dougherty DA. Confirming the revised C-terminal domain of the MscL crystal structure. Biophysical Journal. 94: 4662-7. PMID 18326638 DOI: 10.1529/biophysj.107.127365  1
2008 Bower KS, Price KL, Sturdee LE, Dayrell M, Dougherty DA, Lummis SC. 5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function. European Journal of Pharmacology. 580: 291-7. PMID 18082160 DOI: 10.1016/j.ejphar.2007.11.014  1
2008 Ahern CA, Eastwood AL, Dougherty DA, Horn R. Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels. Circulation Research. 102: 86-94. PMID 17967784 DOI: 10.1161/CIRCRESAHA.107.160663  1
2007 Rodriguez EA, Lester HA, Dougherty DA. Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 1: minimizing misacylation. Rna (New York, N.Y.). 13: 1703-14. PMID 17698638 DOI: 10.1261/rna.666807  1
2007 Rodriguez EA, Lester HA, Dougherty DA. Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 2: evaluating suppression efficiency. Rna (New York, N.Y.). 13: 1715-22. PMID 17698637 DOI: 10.1261/rna.667607  1
2007 Kedrowski SM, Bower KS, Dougherty DA. 1-Oxo-5-hydroxytryptamine: a surprisingly potent agonist of the 5-HT3 (serotonin) receptor. Organic Letters. 9: 3205-7. PMID 17637025 DOI: 10.1021/ol071083s  1
2007 Wang J, Lester HA, Dougherty DA. Establishing an ion pair interaction in the homomeric rho1 gamma-aminobutyric acid type A receptor that contributes to the gating pathway. The Journal of Biological Chemistry. 282: 26210-6. PMID 17606618 DOI: 10.1074/jbc.M702314200  1
2007 Santarelli VP, Eastwood AL, Dougherty DA, Ahern CA, Horn R. Calcium block of single sodium channels: role of a pore-lining aromatic residue. Biophysical Journal. 93: 2341-9. PMID 17545248 DOI: 10.1529/biophysj.107.106856  1
2007 Dougherty DA. Cation-pi interactions involving aromatic amino acids. The Journal of Nutrition. 137: 1504S-1508S; discuss. PMID 17513416  1
2007 Padgett CL, Hanek AP, Lester HA, Dougherty DA, Lummis SC. Unnatural amino acid mutagenesis of the GABA(A) receptor binding site residues reveals a novel cation-pi interaction between GABA and beta 2Tyr97. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 886-92. PMID 17251430 DOI: 10.1523/JNEUROSCI.4791-06.2007  1
2007 Santarelli VP, Eastwood AL, Dougherty DA, Horn R, Ahern CA. A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block. The Journal of Biological Chemistry. 282: 8044-51. PMID 17237232 DOI: 10.1074/jbc.M611334200  1
2007 Cashin AL, Torrice MM, McMenimen KA, Lester HA, Dougherty DA. Chemical-scale studies on the role of a conserved aspartate in preorganizing the agonist binding site of the nicotinic acetylcholine receptor. Biochemistry. 46: 630-9. PMID 17223685 DOI: 10.1021/bi061638b  1
2007 Maurer JA, White VE, Dougherty DA, Nadeau JL. Reconstitution of ion channels in agarose-supported silicon orifices. Biosensors & Bioelectronics. 22: 2577-84. PMID 17098413 DOI: 10.1016/j.bios.2006.10.017  1
2006 McMenimen KA, Dougherty DA, Lester HA, Petersson EJ. Probing the Mg2+ blockade site of an N-methyl-D-aspartate (NMDA) receptor with unnatural amino acid mutagenesis. Acs Chemical Biology. 1: 227-34. PMID 17163677 DOI: 10.1021/cb6000944  1
2006 Ahern CA, Eastwood AL, Lester HA, Dougherty DA, Horn R. A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels. The Journal of General Physiology. 128: 649-57. PMID 17130518 DOI: 10.1085/jgp.200609654  1
2006 Rodriguez EA, Lester HA, Dougherty DA. In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression. Proceedings of the National Academy of Sciences of the United States of America. 103: 8650-5. PMID 16728509 DOI: 10.1073/pnas.0510817103  1
2006 Spronk SA, Elmore DE, Dougherty DA. Voltage-dependent hydration and conduction properties of the hydrophobic pore of the mechanosensitive channel of small conductance. Biophysical Journal. 90: 3555-69. PMID 16500980 DOI: 10.1529/biophysj.105.080432  1
2005 Lummis SC, Beene DL, Lee LW, Lester HA, Broadhurst RW, Dougherty DA. Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel. Nature. 438: 248-52. PMID 16281040 DOI: 10.1038/nature04130  1
2005 Xiu X, Hanek AP, Wang J, Lester HA, Dougherty DA. A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors. The Journal of Biological Chemistry. 280: 41655-66. PMID 16216879 DOI: 10.1074/jbc.M508635200  1
2005 Lummis SC, L Beene D, Harrison NJ, Lester HA, Dougherty DA. A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor. Chemistry & Biology. 12: 993-7. PMID 16183023 DOI: 10.1016/j.chembiol.2005.06.012  1
2005 Rothman DM, Petersson EJ, Vázquez ME, Brandt GS, Dougherty DA, Imperiali B. Caged phosphoproteins. Journal of the American Chemical Society. 127: 846-7. PMID 15656617 DOI: 10.1021/ja043875c  1
2005 Cashin AL, Petersson EJ, Lester HA, Dougherty DA. Using physical chemistry to differentiate nicotinic from cholinergic agonists at the nicotinic acetylcholine receptor. Journal of the American Chemical Society. 127: 350-6. PMID 15631485 DOI: 10.1021/ja0461771  1
2004 Beene DL, Price KL, Lester HA, Dougherty DA, Lummis SC. Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9097-104. PMID 15483128 DOI: 10.1523/JNEUROSCI.2429-04.2004  1
2004 Dahan DS, Dibas MI, Petersson EJ, Auyeung VC, Chanda B, Bezanilla F, Dougherty DA, Lester HA. A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proceedings of the National Academy of Sciences of the United States of America. 101: 10195-200. PMID 15218096 DOI: 10.1073/pnas.0301885101  1
2004 Lester HA, Dibas MI, Dahan DS, Leite JF, Dougherty DA. Cys-loop receptors: new twists and turns. Trends in Neurosciences. 27: 329-36. PMID 15165737 DOI: 10.1016/j.tins.2004.04.002  1
2004 Clayton D, Shapovalov G, Maurer JA, Dougherty DA, Lester HA, Kochendoerfer GG. Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 101: 4764-9. PMID 15041744 DOI: 10.1073/pnas.0305693101  1
2003 Leite JF, Blanton MP, Shahgholi M, Dougherty DA, Lester HA. Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: electrophysiology-coordinated photochemistry and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 100: 13054-9. PMID 14569028 DOI: 10.1073/pnas.2133028100  1
2003 Elmore DE, Dougherty DA. Investigating lipid composition effects on the mechanosensitive channel of large conductance (MscL) using molecular dynamics simulations. Biophysical Journal. 85: 1512-24. PMID 12944269 DOI: 10.1016/S0006-3495(03)74584-6  1
2003 Leite JF, Dougherty DA, Lester HA, Shahgholi M. Investigation of apparent mass deviations in electrospray ionization tandem mass spectrometry of a benzophenone-labeled peptide. Rapid Communications in Mass Spectrometry : Rcm. 17: 1677-84. PMID 12872270 DOI: 10.1002/rcm.1103  1
2003 Beene DL, Dougherty DA, Lester HA. Unnatural amino acid mutagenesis in mapping ion channel function. Current Opinion in Neurobiology. 13: 264-70. PMID 12850209 DOI: 10.1016/S0959-4388(03)00068-0  1
2003 Monahan SL, Lester HA, Dougherty DA. Site-specific incorporation of unnatural amino acids into receptors expressed in Mammalian cells. Chemistry & Biology. 10: 573-80. PMID 12837390 DOI: 10.1016/S1074-5521(03)00124-8  1
2003 Mu TW, Lester HA, Dougherty DA. Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge? Journal of the American Chemical Society. 125: 6850-1. PMID 12783521 DOI: 10.1021/ja0348086  1
2003 Maurer JA, Dougherty DA. Generation and evaluation of a large mutational library from the Escherichia coli mechanosensitive channel of large conductance, MscL: implications for channel gating and evolutionary design. The Journal of Biological Chemistry. 278: 21076-82. PMID 12670944 DOI: 10.1074/jbc.M302892200  1
2003 Petersson EJ, Brandt GS, Zacharias NM, Dougherty DA, Lester HA. Caging proteins through unnatural amino acid mutagenesis. Methods in Enzymology. 360: 258-73. PMID 12622154 DOI: 10.1016/S0076-6879(03)60114-X  1
2002 Petersson EJ, Choi A, Dahan DS, Lester HA, Dougherty DA. A perturbed pK(a) at the binding site of the nicotinic acetylcholine receptor: implications for nicotine binding. Journal of the American Chemical Society. 124: 12662-3. PMID 12392404  1
2002 Beene DL, Brandt GS, Zhong W, Zacharias NM, Lester HA, Dougherty DA. Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine. Biochemistry. 41: 10262-9. PMID 12162741 DOI: 10.1021/bi020266d  1
2002 Zacharias N, Dougherty DA. Cation-pi interactions in ligand recognition and catalysis. Trends in Pharmacological Sciences. 23: 281-7. PMID 12084634 DOI: 10.1016/S0165-6147(02)02027-8  1
2002 Petersson EJ, Shahgholi M, Lester HA, Dougherty DA. MALDI-TOF mass spectrometry methods for evaluation of in vitro aminoacyl tRNA production. Rna (New York, N.Y.). 8: 542-7. PMID 11991647 DOI: 10.1017/S1355838202026146  1
2002 Petersson EJ, Choi A, Dahan DS, Lester HA, Dougherty DA. A perturbed pKa at the binding site of the nicotinic acetylcholine receptor: Implications for nicotine binding Journal of the American Chemical Society. 124: 12662-12663. DOI: 10.1021/ja028206i  1
2001 Dougherty DA. Polymer stereochemistry: an opportunity and a challenge on Titan. Enantiomer. 6: 101-6. PMID 11570417  1
2001 Maurer JA, Dougherty DA. A high-throughput screen for MscL channel activity and mutational phenotyping. Biochimica Et Biophysica Acta. 1514: 165-9. PMID 11557017 DOI: 10.1016/S0005-2736(01)00390-X  1
2001 Elmore DE, Dougherty DA. Molecular dynamics simulations of wild-type and mutant forms of the Mycobacterium tuberculosis MscL channel. Biophysical Journal. 81: 1345-59. PMID 11509350 DOI: 10.1016/S0006-3495(01)75791-8  1
2001 Philipson KD, Gallivan JP, Brandt GS, Dougherty DA, Lester HA. Incorporation of caged cysteine and caged tyrosine into a transmembrane segment of the nicotinic ACh receptor. American Journal of Physiology. Cell Physiology. 281: C195-206. PMID 11401842  1
2001 Dougherty DA, Lester HA. Neurobiology. Snails, synapses and smokers. Nature. 411: 252-3, 255. PMID 11357112 DOI: 10.1038/35077192  1
2001 Li L, Zhong W, Zacharias N, Gibbs C, Lester HA, Dougherty DA. The tethered agonist approach to mapping ion channel proteins--toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor. Chemistry & Biology. 8: 47-58. PMID 11182318 DOI: 10.1016/S1074-5521(00)00055-7  1
2001 Tong Y, Brandt GS, Li M, Shapovalov G, Slimko E, Karschin A, Dougherty DA, Lester HA. Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channel. The Journal of General Physiology. 117: 103-18. PMID 11158164 DOI: 10.1085/jgp.117.2.103  1
2001 Dougherty DA, Lester HA. Snails, synapses and smokers Nature. 411: 252-255.  1
2000 Dougherty DA. Unnatural amino acids as probes of protein structure and function. Current Opinion in Chemical Biology. 4: 645-52. PMID 11102869 DOI: 10.1016/S1367-5931(00)00148-4  1
2000 Dang H, England PM, Farivar SS, Dougherty DA, Lester HA. Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating. Molecular Pharmacology. 57: 1114-22. PMID 10825381  1
2000 Elmore DE, Dougherty DA. A computational study of nicotine conformations in the gas phase and in water. The Journal of Organic Chemistry. 65: 742-7. PMID 10814006 DOI: 10.1021/jo991383q  1
2000 Maurer JA, Elmore DE, Lester HA, Dougherty DA. Comparing and contrasting Escherichia coli and Mycobacterium tuberculosis mechanosensitive channels (MscL). New gain of function mutations in the loop region. The Journal of Biological Chemistry. 275: 22238-44. PMID 10801868 DOI: 10.1074/jbc.M003056200  1
2000 Gallivan JP, Dougherty DA. A computational study of cation-π interactions vs salt bridges in aqueous media: Implications for protein engineering Journal of the American Chemical Society. 122: 870-874. DOI: 10.1021/ja991755c  1
1999 Gallivan JP, Dougherty DA. Can lone pairs bind to a pi system? The water...hexafluorobenzene interaction. Organic Letters. 1: 103-5. PMID 10822544  1
1999 England PM, Lester HA, Dougherty DA. Mapping disulfide connectivity using backbone ester hydrolysis. Biochemistry. 38: 14409-15. PMID 10572015 DOI: 10.1021/bi991424c  1
1999 Gallivan JP, Dougherty DA. Cation-pi interactions in structural biology. Proceedings of the National Academy of Sciences of the United States of America. 96: 9459-64. PMID 10449714 DOI: 10.1073/pnas.96.17.9459  1
1999 England PM, Zhang Y, Dougherty DA, Lester HA. Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating. Cell. 96: 89-98. PMID 9989500 DOI: 10.1016/S0092-8674(00)80962-9  1
1999 Ngola SM, Kearney PC, Mecozzi S, Russell K, Dougherty DA. A selective receptor for arginine derivatives in aqueous media. Energetic consequences of salt bridges that are highly exposed to water Journal of the American Chemical Society. 121: 1192-1201. DOI: 10.1021/ja982499r  1
1999 England PM, Lester HA, Dougherty DA. Incorporation of esters into proteins: Improved synthesis of hydroxyacyl tRNAs Tetrahedron Letters. 40: 6189-6192. DOI: 10.1016/S0040-4039(99)01300-3  1
1998 Dougherty DA, Lester HA. The Crystal Structure of a Potassium Channel- A New Era in the Chemistry of Biological Signaling. Angewandte Chemie (International Ed. in English). 37: 2329-2331. PMID 29710958 DOI: 10.1002/(SICI)1521-3773(19980918)37:17<2329::AID-ANIE2329>3.0.CO;2-M  1
1998 Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, Dougherty DA. From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 95: 12088-93. PMID 9770444 DOI: 10.1073/pnas.95.21.12088  1
1998 Silverman SK, Lester HA, Dougherty DA. Asymmetrical contributions of subunit pore regions to ion selectivity in an inward rectifier K+ channel. Biophysical Journal. 75: 1330-9. PMID 9726934 DOI: 10.1016/S0006-3495(98)74051-2  1
1998 Nowak MW, Gallivan JP, Silverman SK, Labarca CG, Dougherty DA, Lester HA. In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system. Methods in Enzymology. 293: 504-29. PMID 9711626 DOI: 10.1016/S0076-6879(98)93031-2  1
1998 Miller JC, Silverman SK, England PM, Dougherty DA, Lester HA. Flash decaging of tyrosine sidechains in an ion channel. Neuron. 20: 619-24. PMID 9581754 DOI: 10.1016/S0896-6273(00)81001-6  1
1998 Dougherty DA. Stereochemical issues in studies of ion channel proteins. Chirality. 10: 8-13. PMID 9470205 DOI: 10.1002/(SICI)1520-636X(1998)10:1/2<8::AID-CHIR3>3.0.CO;2-6  1
1998 Lester HA, Dougherty DA. New views of multi-ion channels. The Journal of General Physiology. 111: 181-3. PMID 9450937  1
1998 Dougherty DA, Lester HA. The crystal structure of a potassium channel - A new era in the chemistry of biological signaling Angewandte Chemie - International Edition. 37: 2329-2331. DOI: 10.1002/(SICI)1521-3773(19980918)37:17<2329::AID-ANIE2329>3.0.CO;2-M  1
1998 Ngola SM, Dougherty DA. Concerning the Effects of Aromatic Ring Fluorination on the Cation-π Interaction and Other Molecular Recognition Phenomena in Aqueous Media Journal of Organic Chemistry. 63: 4566-4567.  1
1998 Anderson KK, Dougherty DA. An improved model for one-dimensional polaronic ferromagnetism: Electrochemically doped poly (m-phenylenefuchsone) Advanced Materials. 10: 688-692.  1
1998 Dougherty DA. Is the brain ready for physical organic chemistry? Journal of Physical Organic Chemistry. 11: 334-340.  1
1997 Ma JC, Dougherty DA. The Cationminus signpi Interaction. Chemical Reviews. 97: 1303-1324. PMID 11851453  0.88
1997 England PM, Lester HA, Davidson N, Dougherty DA. Site-specific, photochemical proteolysis applied to ion channels in vivo. Proceedings of the National Academy of Sciences of the United States of America. 94: 11025-30. PMID 9380753 DOI: 10.1073/pnas.94.20.11025  1
1997 Gallivan JP, Lester HA, Dougherty DA. Site-specific incorporation of biotinylated amino acids to identify surface-exposed residues in integral membrane proteins. Chemistry & Biology. 4: 739-49. PMID 9375252  1
1997 West AP, Bjorkman PJ, Dougherty DA, Lester HA. Expression and circular dichroism studies of the extracellular domain of the alpha subunit of the nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 272: 25468-73. PMID 9325259 DOI: 10.1074/jbc.272.41.25468  1
1997 Anderson KK, Shultz DA, Dougherty DA. Attempted Synthesis of a Stable, Quintet, Tetraphenoxyl Tetraradical: Facile Rearrangement of a Substituted Bicyclobutane Journal of Organic Chemistry. 62: 7575-7584.  1
1997 Dougherty DA. Physical organic chemistry in the brain Pure and Applied Chemistry. 69: 1969-1977.  1
1997 West AP, Mecozzi S, Dougherty DA. Theoretical studies of the supramolecular synthon benzene ⋯ hexafluorobenzene Journal of Physical Organic Chemistry. 10: 347-350.  1
1997 Coates GW, Dunn AR, Henling LM, Dougherty DA, Grubbs RH. Phenyl-perfluorophenyl stacking interactions: A new strategy for supermolecule construction Angewandte Chemie - International Edition in English. 36: 248-251.  1
1996 Ngola SM, Dougherty DA. Evidence for the Importance of Polarizability in Biomimetic Catalysis Involving Cyclophane Receptors. The Journal of Organic Chemistry. 61: 4355-4360. PMID 11667337  1
1996 Silverman SK, Kofuji P, Dougherty DA, Davidson N, Lester HA. A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation. Proceedings of the National Academy of Sciences of the United States of America. 93: 15429-34. PMID 8986828 DOI: 10.1073/pnas.93.26.15429  1
1996 Kearney PC, Zhang H, Zhong W, Dougherty DA, Lester HA. Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9' position. Neuron. 17: 1221-9. PMID 8982168 DOI: 10.1016/S0896-6273(00)80252-4  1
1996 Silverman SK, Lester HA, Dougherty DA. Subunit stoichiometry of a heteromultimeric G protein-coupled inward-rectifier K+ channel. The Journal of Biological Chemistry. 271: 30524-8. PMID 8940021 DOI: 10.1074/jbc.271.48.30524  1
1996 Kearney PC, Nowak MW, Zhong W, Silverman SK, Lester HA, Dougherty DA. Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists. Molecular Pharmacology. 50: 1401-12. PMID 8913372  1
1996 Mecozzi S, West AP, Dougherty DA. Cation-pi interactions in aromatics of biological and medicinal interest: electrostatic potential surfaces as a useful qualitative guide. Proceedings of the National Academy of Sciences of the United States of America. 93: 10566-71. PMID 8855218 DOI: 10.1073/pnas.93.20.10566  1
1996 Saks ME, Sampson JR, Nowak MW, Kearney PC, Du F, Abelson JN, Lester HA, Dougherty DA. An engineered Tetrahymena tRNAGln for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression. The Journal of Biological Chemistry. 271: 23169-75. PMID 8798511 DOI: 10.1074/jbc.271.38.23169  1
1996 Dougherty DA. Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science (New York, N.Y.). 271: 163-8. PMID 8539615  1
1996 Mecozzi S, West AP, Dougherty DA. Cation-π interactions in simple aromatics: Electrostatics provide a predictive tool Journal of the American Chemical Society. 118: 2307-2308. DOI: 10.1021/ja9539608  1
1996 West AP, Silverman SK, Dougherty DA. Do high-spin topology rules apply to charged polyradicals? Theoretical and experimental evaluation of pyridiniums as magnetic coupling units Journal of the American Chemical Society. 118: 1452-1463. DOI: 10.1021/ja9527941  1
1996 Dougherty DA. Cation-π interactions in chemistry and biology: A new view of benzene, Phe, Tyr, and Trp Science. 271: 345-348.  1
1995 Nowak MW, Kearney PC, Sampson JR, Saks ME, Labarca CG, Silverman SK, Zhong W, Thorson J, Abelson JN, Davidson N. Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells. Science (New York, N.Y.). 268: 439-42. PMID 7716551  1
1995 Forman JE, Barrans RE, Dougherty DA. Circular dichroism studies of molecular recognition with cyclophane hosts in aqueous media Journal of the American Chemical Society. 117: 9213-9228.  1
1994 Murray MM, Kaszynski P, Kaisaki DA, Chang W, Dougherty DA. Prototypes for the polaronic ferromagnet. Synthesis and characterization of high-spin organic polymers Journal of the American Chemical Society. 116: 8152-8161.  1
1994 Jacobs SJ, Dougherty DA. Combination of superexchange and spin-polarization mechanisms leads to a novel hydrocarbon tetraradical with a high-spin ground state Angewandte Chemie (International Edition in English). 33: 1104-1106.  1
1993 Kumpf RA, Dougherty DA. A mechanism for ion selectivity in potassium channels: computational studies of cation-pi interactions. Science (New York, N.Y.). 261: 1708-10. PMID 8378771  1
1993 Kaszynski P, Dougherty DA. Synthesis and properties of diethyl 5,10-dihetera-5,10-dihydroindeno[2,1-a]indene-2,7-dicarboxylates Journal of Organic Chemistry. 58: 5209-5220.  1
1993 Kearney PC, Mizoue LS, Kumpf RA, Forman JE, McCurdy A, Dougherty DA. Molecular recognition in aqueous media. new binding studies provide further insights into the cation-π interaction and related phenomena Journal of the American Chemical Society. 115: 9907-9919.  1
1993 Silverman SK, Dougherty DA. Conformational effects on high-spin organic molecules Journal of Physical Chemistry. 97: 13273-13283.  1
1992 McCurdy A, Jimenez L, Stauffer DA, Dougherty DA. Biomimetic catalysis of SN2 reactions through cation-π interactions. The role of polarizability in catalysis Journal of the American Chemical Society. 114: 10314-10321.  1
1991 Kaisaki DA, Chang W, Dougherty DA. Noval magnetic properties of a doped organic polymer. A possible prototype for a polaronic ferromagnet Journal of the American Chemical Society. 113: 2764-2766.  1
1991 Dougherty DA. Spin control in organic molecules Accounts of Chemical Research. 24: 88-94.  1
1991 Nelsen SF, Petillo PA, Chang H, Frigo TB, Dougherty DA, Kaftory M. Effects of CNN bond angle restriction in 2,3-diazabicyclo[2.1.1]hexane derivatives on nitrogen inversion barrier, ease of oxidation, and acidity Journal of Organic Chemistry. 56: 613-618.  1
1990 Dougherty DA, Stauffer DA. Acetylcholine binding by a synthetic receptor: implications for biological recognition. Science (New York, N.Y.). 250: 1558-60. PMID 2274786  1
1990 Stauffer DA, Barrans RE, Dougherty DA. Concerning the thermodynamics of molecular recognition in aqueous and organic media. Evidence for significant heat capacity effects Journal of Organic Chemistry. 55: 2762-2767.  1
1990 Stauffer DA, Barrans RE, Dougherty DA. Biomimetic catalysis of an SN2 reaction resulting from a novel form of transition-state stabilization Angewandte Chemie (International Edition in English). 29: 915-918.  1
1989 Novak JA, Jain R, Dougherty DA. Cyclobutane as a general ferromagnetic coupling unit. Design and synthesis of a new, hydrocarbon quintet Journal of the American Chemical Society. 111: 7618-7619.  1
1989 Snyder GJ, Dougherty DA. 2,4-Dimethylenebicyclobutane: Preparation, characterization, and relationship to the non-Kekulé isomer of benzene Journal of the American Chemical Society. 111: 3942-3954.  1
1989 Snyder GJ, Dougherty DA. 2,4-Dimethylene-1,3-cyclobutanediyl, the non-Kekulé isomer of benzene. Synthesis, EPR, and electronic spectroscopy Journal of the American Chemical Society. 111: 3927-3942.  1
1989 Sponsler MB, Jain R, Corns FD, Dougherty DA. Matrix-isolation decay kinetics of triplet cyclobutanediyls. Observation of both arrhenius behavior and heavy-atom tunneling in C-C bond-forming reactions Journal of the American Chemical Society. 111: 2240-2252.  1
1989 Pranata J, Marudarajan VS, Dougherty DA. A theoretical study of bi(cyclobutadienyl) and higher homologues. Polycyclobutadiene as a novel organic metal? Journal of the American Chemical Society. 111: 2026-2030.  1
1989 Coms FD, Dougherty DA. Diphenylbicyclo[2.1.0]pentane. A persistent hydrocarbon with a very weak C-C bond Journal of the American Chemical Society. 111: 6894-6896.  1
1988 Stauffer DA, Dougherty DA. Ion-dipole effect as a force for molecular recognition in organic media Tetrahedron Letters. 29: 6039-6042. DOI: 10.1016/S0040-4039(00)82259-5  1
1988 Coms FD, Dougherty DA. 1,3-Diphenyl-1,3-cyclopentanediyl: A remarkably stable localized biradical Tetrahedron Letters. 29: 3753-3756. DOI: 10.1016/S0040-4039(00)82106-1  1
1988 Swager TM, Dougherty DA, Grubbs RH. Strained rings as a source of unsaturation: Polybenzvalene, a new soluble polyacetylene precursor Journal of the American Chemical Society. 110: 2973-2974.  1
1988 Petti MA, Shepodd TJ, Barrans RE, Dougherty DA. "Hydrophobic" binding of water-soluble guests by high-symmetry, chiral hosts. An electron-rich receptor site with a general affinity for quaternary ammonium compounds and electron-deficient π systems Journal of the American Chemical Society. 110: 6825-6840.  1
1988 Jain R, McElwee-White L, Dougherty DA. Rapid, multistep rearrangements of hydrocarbon triplet biradicals at 4 K. A possible example of hot molecule effects in frozen organic solvents Journal of the American Chemical Society. 110: 552-560.  1
1988 Pranata J, Grubbs RH, Dougherty DA. Band structures of polyfulvene and related polymers. A model for the effects of benzannelation on the band structures of polythiophene, polypyrrole, and polyfulvene Journal of the American Chemical Society. 110: 3430-3435.  1
1988 Shepodd TJ, Petti MA, Dougherty DA. Molecular recognition in aqueous media: Donor-acceptor and ion-dipole interactions produce tight binding for highly soluble guests Journal of the American Chemical Society. 110: 1983-1985.  1
1987 Pranata J, Dougherty DA. Non-kekulé acenes. The dimethylenepolycyclobutadienes, a new class of (4n + 2) alternant hydrocarbons Journal of the American Chemical Society. 109: 1621-1627.  1
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