Richard A. Lerner - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
catalytic antibodies
Website:
http://www.scripps.edu/about/lerner_CV.html

264 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liu T, Kuwana T, Zhang H, Vander Heiden MG, Lerner RA, Newmeyer DD. Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1. Plos Biology. 17: e2004413. PMID 31181072 DOI: 10.1371/journal.pbio.2004413  1
2019 Lerner RA, Ma P, Xu H, Li J, Lu F, Ma F, Wang S, Xiong H, Wang W, Buratto D, Zonta F, Wang N, Liu K, Hua T, Yang G. Functionality independent DNA encoding of complex natural products. Angewandte Chemie (International Ed. in English). PMID 31020752 DOI: 10.1002/anie.201901485  1
2019 Yea K, Jones TM, Jung D, Shin S, Arlian BM, Han KH, Zha Z, Kim MS, Oh YS, Zhang H, Lerner RA. An agonist antibody prefers relapsed AML for induction of cells that kill each other. Scientific Reports. 9: 3494. PMID 30837591 DOI: 10.1038/s41598-019-40087-7  1
2018 Stepanov AV, Markov OV, Chernikov IV, Gladkikh DV, Zhang H, Jones T, Sen'kova AV, Chernolovskaya EL, Zenkova MA, Kalinin RS, Rubtsova MP, Meleshko AN, Genkin DD, Belogurov AA, Xie J, ... ... Lerner RA, et al. Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma. Science Advances. 4: eaau4580. PMID 30443597 DOI: 10.1126/sciadv.aau4580  1
2018 Qiang M, Dong X, Zha Z, Zuo XK, Song XL, Zhao L, Yuan C, Huang C, Tao P, Hu Q, Li WG, Hu W, Li J, Nie Y, Buratto D, ... ... Lerner RA, et al. Selection of an ASIC1a-blocking combinatorial antibody that protects cells from ischemic death. Proceedings of the National Academy of Sciences of the United States of America. PMID 30042215 DOI: 10.1073/pnas.1807233115  1
2018 Merkouris S, Barde YA, Binley KE, Allen ND, Stepanov AV, Wu NC, Grande G, Lin CW, Li M, Nan X, Chacon-Fernandez P, DiStefano PS, Lindsay RM, Lerner RA, Xie J. Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987039 DOI: 10.1073/pnas.1806660115  1
2018 Zheng T, Xie J, Yang Z, Tao P, Shi B, Douthit L, Wu P, Lerner RA. Antibody selection using clonal cocultivation of and eukaryotic cells in miniecosystems. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915075 DOI: 10.1073/pnas.1806718115  1
2018 Wu NC, Thompson AJ, Xie J, Lin CW, Nycholat CM, Zhu X, Lerner RA, Paulson JC, Wilson IA. A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nature Communications. 9: 1264. PMID 29593268 DOI: 10.1038/s41467-018-03663-5  1
2018 Yang Z, Du M, Wang W, Xin X, Ma P, Zhang H, Lerner RA. Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity. Protein Engineering, Design & Selection : Peds. PMID 29474709 DOI: 10.1093/protein/gzy002  1
2017 Xu L, Carrer A, Zonta F, Qu Z, Ma P, Li S, Ceriani F, Buratto D, Crispino G, Zorzi V, Ziraldo G, Bruno F, Nardin C, Peres C, Mazzarda F, ... ... Lerner RA, et al. Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders. Frontiers in Molecular Neuroscience. 10: 298. PMID 29018324 DOI: 10.3389/fnmol.2017.00298  1
2017 Lang S, Xie J, Zhu X, Wu NC, Lerner RA, Wilson IA. Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem. Cell Reports. 20: 2935-2943. PMID 28930686 DOI: 10.1016/j.celrep.2017.08.084  1
2017 Blanchard JW, Xie J, El-Mecharrafie N, Gross S, Lee S, Lerner RA, Baldwin KK. Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries. Nature Biotechnology. PMID 28892074 DOI: 10.1038/nbt.3963  1
2017 Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 22: 247-248. PMID 28799910 DOI: 10.1016/j.chom.2017.07.001  1
2017 Zha Z, Bucher F, Nejatfard A, Zheng T, Zhang H, Yea K, Lerner RA. Interferon-γ is a master checkpoint regulator of cytokine-induced differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760993 DOI: 10.1073/pnas.1706915114  1
2017 Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 21: 742-753.e8. PMID 28618270 DOI: 10.1016/j.chom.2017.05.011  1
2017 Wu NC, Grande G, Turner HL, Ward AB, Xie J, Lerner RA, Wilson IA. In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity. Nature Communications. 8: 15371. PMID 28504265 DOI: 10.1038/ncomms15371  1
2017 Xie J, Sok D, Wu NC, Zheng T, Zhang W, Burton DR, Lerner RA. Immunochemical engineering of cell surfaces to generate virus resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396429 DOI: 10.1073/pnas.1702764114  1
2017 Li N, Yu Z, Ji Q, Sun J, Liu X, Du M, Lerner RA, Zhang W. An enzyme-mediated protein-fragment complementation assay for substrate screening of sortase A. Biochemical and Biophysical Research Communications. PMID 28286272 DOI: 10.1016/j.bbrc.2017.03.016  1
2017 Zhang H, Lerner RA. A Proximity-Based Assay for Identification of Ligand and Membrane Protein Interaction in Living Cells. Methods in Molecular Biology (Clifton, N.J.). 1575: 215-222. PMID 28255883 DOI: 10.1007/978-1-4939-6857-2_13  1
2016 Lerner RA. Combinatorial antibody libraries: new advances, new immunological insights. Nature Reviews. Immunology. PMID 27374636 DOI: 10.1038/nri.2016.67  0.01
2016 Zhang H, Du M, Xie J, Liu X, Sun J, Wang W, Xin X, Possani LD, Yea K, Lerner RA. Autocrine-Based Selection of Drugs that Target Ion Channels from Combinatorial Venom Peptide Libraries. Angewandte Chemie (International Ed. in English). PMID 27197631 DOI: 10.1002/anie.201603052  1
2015 Zhang H, Sturchler E, Zhu J, Nieto A, Cistrone PA, Xie J, He L, Yea K, Jones T, Turn R, Di Stefano PS, Griffin PR, Dawson PE, McDonald PH, Lerner RA. Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects. Nature Communications. 6: 8918. PMID 26621478 DOI: 10.1038/ncomms9918  1
2015 Yea K, Zhang H, Lerner RA. Activating pleiotropic receptors to kill cancer cells. Cell Cycle (Georgetown, Tex.). 0. PMID 26588245 DOI: 10.1080/15384101.2015.1118912  1
2015 Lerner RA, Grover RK, Zhang H, Xie J, Han KH, Peng Y, Yea K. Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates. Quarterly Reviews of Biophysics. 48: 389-94. PMID 26537396 DOI: 10.1017/S0033583515000049  1
2015 Yea K, Zhang H, Xie J, Jones TM, Lin CW, Francesconi W, Berton F, Fallahi M, Sauer K, Lerner RA. Agonist antibody that induces human malignant cells to kill one another. Proceedings of the National Academy of Sciences of the United States of America. PMID 26487683 DOI: 10.1073/pnas.1519079112  1
2015 Han KH, Gonzalez-Quintial R, Peng Y, Baccala R, Theofilopoulos AN, Lerner RA. An agonist antibody that blocks autoimmunity by inducing anti-inflammatory macrophages. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26481307 DOI: 10.1096/fj.15-281329  1
2015 Peng Y, Zeng W, Ye H, Han KH, Dharmarajan V, Novick S, Wilson IA, Griffin PR, Friedman JM, Lerner RA. A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. Chemistry & Biology. 22: 1134-43. PMID 26278185 DOI: 10.1016/j.chembiol.2015.07.011  1
2015 Yea K, Xie J, Zhang H, Zhang W, Lerner RA. Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic. Current Opinion in Chemical Biology. 26: 1-7. PMID 25621729 DOI: 10.1016/j.cbpa.2015.01.002  1
2014 Zhang H, Xie J, Lerner RA. A proximity based general method for identification of ligand and receptor interactions in living cells. Biochemical and Biophysical Research Communications. 454: 251-5. PMID 25451250 DOI: 10.1016/j.bbrc.2014.10.085  1
2014 Lerner RA. Gerald Maurice Edelman. Proceedings of the National Academy of Sciences of the United States of America. 111: 10900-1. PMID 25049421 DOI: 10.1073/pnas.1410861111  1
2014 Grover RK, Zhu X, Nieusma T, Jones T, Boero I, MacLeod AS, Mark A, Niessen S, Kim HJ, Kong L, Assad-Garcia N, Kwon K, Chesi M, Smider VV, Salomon DR, ... ... Lerner RA, et al. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science (New York, N.Y.). 343: 656-61. PMID 24503852 DOI: 10.1126/science.1246135  1
2014 Xie J, Yea K, Zhang H, Moldt B, He L, Zhu J, Lerner RA. Prevention of cell death by antibodies selected from intracellular combinatorial libraries. Chemistry & Biology. 21: 274-83. PMID 24440080 DOI: 10.1016/j.chembiol.2013.12.006  1
2013 Yea K, Zhang H, Xie J, Jones TM, Yang G, Song BD, Lerner RA. Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections. Proceedings of the National Academy of Sciences of the United States of America. 110: 14966-71. PMID 23980154 DOI: 10.1073/pnas.1313671110  1
2013 Zhang H, Yea K, Xie J, Ruiz D, Wilson IA, Lerner RA. Selecting agonists from single cells infected with combinatorial antibody libraries. Chemistry & Biology. 20: 734-41. PMID 23706638 DOI: 10.1016/j.chembiol.2013.04.012  1
2013 Xie J, Zhang H, Yea K, Lerner RA. Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 8099-104. PMID 23613575 DOI: 10.1073/pnas.1306263110  1
2013 Peng Y, Kim DH, Jones TM, Ruiz DI, Lerner RA. Engineering cell surfaces for orthogonal selectability. Angewandte Chemie (International Ed. in English). 52: 336-40. PMID 23239476 DOI: 10.1002/anie.201201844  1
2013 Goswami RK, Liu Y, Liu C, Lerner RA, Sinha SC. Synthesis and evaluation of the aldolase antibody-derived chemical-antibodies targeting α5β1 integrin. Molecular Pharmaceutics. 10: 538-43. PMID 23102054 DOI: 10.1021/mp3004463  1
2012 Zhang H, Wilson IA, Lerner RA. Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries. Proceedings of the National Academy of Sciences of the United States of America. 109: 15728-33. PMID 23019357 DOI: 10.1073/pnas.1214275109  1
2012 Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, ... Lerner RA, et al. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature. 489: 526-32. PMID 22982990 DOI: 10.1038/nature11414  1
2012 Cheng J, Torkamani A, Peng Y, Jones TM, Lerner RA. Plasma membrane associated transcription of cytoplasmic DNA. Proceedings of the National Academy of Sciences of the United States of America. 109: 10827-31. PMID 22711823 DOI: 10.1073/pnas.1208716109  1
2012 Grover RK, Cheng J, Peng Y, Jones TM, Ruiz DI, Ulevitch RJ, Glass JI, Dennis EA, Salomon DR, Lerner RA. The costimulatory immunogen LPS induces the B-Cell clones that infiltrate transplanted human kidneys. Proceedings of the National Academy of Sciences of the United States of America. 109: 6036-41. PMID 22492977 DOI: 10.1073/pnas.1202214109  1
2011 Zhang H, Torkamani A, Jones TM, Ruiz DI, Pons J, Lerner RA. Phenotype-information-phenotype cycle for deconvolution of combinatorial antibody libraries selected against complex systems. Proceedings of the National Academy of Sciences of the United States of America. 108: 13456-61. PMID 21825149 DOI: 10.1073/pnas.1111218108  1
2011 Goswami RK, Bajjuri KM, Forsyth JS, Das S, Hassenpflug W, Huang ZZ, Lerner RA, Felding-Habermann B, Sinha SC. Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro. Bioconjugate Chemistry. 22: 1535-44. PMID 21774545 DOI: 10.1021/bc2000879  1
2011 Gauba V, Grünewald J, Gorney V, Deaton LM, Kang M, Bursulaya B, Ou W, Lerner RA, Schmedt C, Geierstanger BH, Schultz PG, Ramirez-Montagut T. Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids. Proceedings of the National Academy of Sciences of the United States of America. 108: 12821-6. PMID 21768354 DOI: 10.1073/pnas.1110042108  1
2011 Cheng J, Torkamani A, Grover RK, Jones TM, Ruiz DI, Schork NJ, Quigley MM, Hall FW, Salomon DR, Lerner RA. Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal. Proceedings of the National Academy of Sciences of the United States of America. 108: 5560-5. PMID 21415369 DOI: 10.1073/pnas.1101148108  1
2011 Lerner RA. Rare antibodies from combinatorial libraries suggests an S.O.S. component of the human immunological repertoire. Molecular Biosystems. 7: 1004-12. PMID 21298133 DOI: 10.1039/c0mb00310g  1
2010 Doppalapudi VR, Huang J, Liu D, Jin P, Liu B, Li L, Desharnais J, Hagen C, Levin NJ, Shields MJ, Parish M, Murphy RE, Del Rosario J, Oates BD, Lai JY, ... ... Lerner RA, et al. Chemical generation of bispecific antibodies. Proceedings of the National Academy of Sciences of the United States of America. 107: 22611-6. PMID 21149738 DOI: 10.1073/pnas.1016478108  1
2010 Kashyap AK, Steel J, Rubrum A, Estelles A, Briante R, Ilyushina NA, Xu L, Swale RE, Faynboym AM, Foreman PK, Horowitz M, Horowitz L, Webby R, Palese P, Lerner RA, et al. Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivor-based libraries. Plos Pathogens. 6: e1000990. PMID 20628565 DOI: 10.1371/journal.ppat.1000990  1
2010 Xu L, Estellés A, Briante R, Kurtzman AL, Hannum CH, Kashyap AK, Horowitz L, Horowitz M, Bhatt RR, Lerner RA. Surrobodies with functional tails. Journal of Molecular Biology. 397: 352-60. PMID 20100493 DOI: 10.1016/j.jmb.2010.01.036  1
2009 Zhu X, Tanaka F, Lerner RA, Barbas CF, Wilson IA. Direct observation of an enamine intermediate in amine catalysis. Journal of the American Chemical Society. 131: 18206-7. PMID 19968282 DOI: 10.1021/ja907271a  1
2009 Grünewald J, Hunt GS, Dong L, Niessen F, Wen BG, Tsao ML, Perera R, Kang M, Laffitte BA, Azarian S, Ruf W, Nasoff M, Lerner RA, Schultz PG, Smider VV. Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 106: 4337-42. PMID 19246393 DOI: 10.1073/pnas.0900507106  1
2009 Bowley DR, Jones TM, Burton DR, Lerner RA. Libraries against libraries for combinatorial selection of replicating antigen-antibody pairs. Proceedings of the National Academy of Sciences of the United States of America. 106: 1380-5. PMID 19139405 DOI: 10.1073/pnas.0812291106  1
2008 Grünewald J, Tsao ML, Perera R, Dong L, Niessen F, Wen BG, Kubitz DM, Smider VV, Ruf W, Nasoff M, Lerner RA, Schultz PG. Immunochemical termination of self-tolerance. Proceedings of the National Academy of Sciences of the United States of America. 105: 11276-80. PMID 18685087 DOI: 10.1073/pnas.0804157105  1
2008 Xu L, Yee H, Chan C, Kashyap AK, Horowitz L, Horowitz M, Bhatt RR, Lerner RA. Combinatorial surrobody libraries. Proceedings of the National Academy of Sciences of the United States of America. 105: 10756-61. PMID 18664586 DOI: 10.1073/pnas.0805293105  1
2008 Nieva J, Shafton A, Altobell LJ, Tripuraneni S, Rogel JK, Wentworth AD, Lerner RA, Wentworth P. Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation. Biochemistry. 47: 7695-705. PMID 18578541 DOI: 10.1021/bi800333s  1
2008 Tanaka F, Hu Y, Sutton J, Asawapornmongkol L, Fuller R, Olson AJ, Barbas CF, Lerner RA. Selection of phage-displayed peptides that bind to a particular ligand-bound antibody. Bioorganic & Medicinal Chemistry. 16: 5926-31. PMID 18472269 DOI: 10.1016/j.bmc.2008.04.062  1
2008 Kashyap AK, Steel J, Oner AF, Dillon MA, Swale RE, Wall KM, Perry KJ, Faynboym A, Ilhan M, Horowitz M, Horowitz L, Palese P, Bhatt RR, Lerner RA. Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies. Proceedings of the National Academy of Sciences of the United States of America. 105: 5986-91. PMID 18413603 DOI: 10.1073/pnas.0801367105  1
2008 Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA. Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex. Science (New York, N.Y.). 319: 1232-5. PMID 18309081 DOI: 10.1126/science.1153445  1
2008 Willis B, Eubanks LM, Wood MR, Janda KD, Dickerson TJ, Lerner RA. Biologically templated organic polymers with nanoscale order. Proceedings of the National Academy of Sciences of the United States of America. 105: 1416-9. PMID 18216240 DOI: 10.1073/pnas.0711308105  1
2007 Dickerson TJ, McKenzie KM, Hoyt AS, Wood MR, Janda KD, Brenner SB, Lerner RA. Phage escape libraries for checkmate analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12703-8. PMID 17646645 DOI: 10.1073/pnas.0705362104  1
2007 Sinha SC, Das S, Li LS, Lerner RA, Barbas CF. Preparation of integrin alpha(v)beta3-targeting Ab 38C2 constructs. Nature Protocols. 2: 449-56. PMID 17406606 DOI: 10.1038/nprot.2007.3  1
2007 Abraham S, Guo F, Li LS, Rader C, Liu C, Barbas CF, Lerner RA, Sinha SC. Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 5584-9. PMID 17372220 DOI: 10.1073/pnas.0700223104  1
2007 Tanaka F, Jones T, Kubitz D, Lerner RA. Anti-formyl peptide antibodies. Bioorganic & Medicinal Chemistry Letters. 17: 1943-5. PMID 17293112 DOI: 10.1016/j.bmcl.2007.01.082  1
2006 Lerner RA. Manufacturing immunity to disease in a test tube: the magic bullet realized. Angewandte Chemie (International Ed. in English). 45: 8106-25. PMID 17120282 DOI: 10.1002/anie.200603381  1
2006 Bieschke J, Zhang Q, Bosco DA, Lerner RA, Powers ET, Wentworth P, Kelly JW. Small molecule oxidation products trigger disease-associated protein misfolding. Accounts of Chemical Research. 39: 611-9. PMID 16981677 DOI: 10.1021/ar0500766  1
2006 Lerner RA. Retrospective. R. Bruce Merrifield (1921-2006). Science (New York, N.Y.). 313: 57. PMID 16825560 DOI: 10.1126/science.1130957  1
2006 Guo F, Das S, Mueller BM, Barbas CF, Lerner RA, Sinha SC. Breaking the one antibody-one target axiom. Proceedings of the National Academy of Sciences of the United States of America. 103: 11009-14. PMID 16822849 DOI: 10.1073/pnas.0603822103  1
2006 Takeuchi C, Galvé R, Nieva J, Witter DP, Wentworth AD, Troseth RP, Lerner RA, Wentworth P. Proatherogenic effects of the cholesterol ozonolysis products, atheronal-A and atheronal-B. Biochemistry. 45: 7162-70. PMID 16752907 DOI: 10.1021/bi0604330  1
2006 Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW. Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nature Chemical Biology. 2: 249-53. PMID 16565714 DOI: 10.1038/nchembio782  1
2006 Zhu X, Wentworth P, Kyle RA, Lerner RA, Wilson IA. Cofactor-containing antibodies: crystal structure of the original yellow antibody. Proceedings of the National Academy of Sciences of the United States of America. 103: 3581-5. PMID 16537445 DOI: 10.1073/pnas.0600251103  1
2006 Nieva J, Kerwin L, Wentworth AD, Lerner RA, Wentworth P. Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway. Immunology Letters. 103: 33-8. PMID 16386801 DOI: 10.1016/j.imlet.2005.11.020  1
2005 Matsushita H, Yamamoto N, Meijler MM, Wirsching P, Lerner RA, Matsushita M, Janda KD. Chiral sensing using a blue fluorescent antibody. Molecular Biosystems. 1: 303-6. PMID 16880995 DOI: 10.1039/b511408j  1
2005 Matsushita M, Meijler MM, Wirsching P, Lerner RA, Janda KD. A blue fluorescent antibody-cofactor sensor for mercury. Organic Letters. 7: 4943-6. PMID 16235928 DOI: 10.1021/ol051919w  1
2005 Weinstain R, Lerner RA, Barbas CF, Shabat D. Antibody-catalyzed asymmetric intramolecular Michael addition of aldehydes and ketones to yield the disfavored cis-product. Journal of the American Chemical Society. 127: 13104-5. PMID 16173712 DOI: 10.1021/ja0536825  1
2005 Li LS, Babendure JL, Sinha SC, Olefsky JM, Lerner RA. Synthesis and evaluation of photolabile insulin prodrugs. Bioorganic & Medicinal Chemistry Letters. 15: 3917-20. PMID 15993597 DOI: 10.1016/j.bmcl.2005.05.112  1
2005 Amir RJ, Popkov M, Lerner RA, Barbas CF, Shabat D. Prodrug activation gated by a molecular "OR" logic trigger. Angewandte Chemie (International Ed. in English). 44: 4378-81. PMID 15942963 DOI: 10.1002/anie.200500842  1
2005 Rajpal A, Beyaz N, Haber L, Cappuccilli G, Yee H, Bhatt RR, Takeuchi T, Lerner RA, Crea R. A general method for greatly improving the affinity of antibodies by using combinatorial libraries. Proceedings of the National Academy of Sciences of the United States of America. 102: 8466-71. PMID 15939870 DOI: 10.1073/pnas.0503543102  1
2005 Bieschke J, Zhang Q, Powers ET, Lerner RA, Kelly JW. Oxidative metabolites accelerate Alzheimer's amyloidogenesis by a two-step mechanism, eliminating the requirement for nucleation. Biochemistry. 44: 4977-83. PMID 15794636 DOI: 10.1021/bi0501030  1
2005 Kaufmann GF, Meijler MM, Sun C, Chen DW, Kujawa DP, Mee JM, Hoffman TZ, Wirsching P, Lerner RA, Janda KD. Enzymatic incorporation of an antibody-activated blue fluorophore into DNA. Angewandte Chemie (International Ed. in English). 44: 2144-8. PMID 15742317 DOI: 10.1002/anie.200461143  1
2005 Haba K, Popkov M, Shamis M, Lerner RA, Barbas CF, Shabat D. Single-triggered trimeric prodrugs. Angewandte Chemie (International Ed. in English). 44: 716-20. PMID 15657968 DOI: 10.1002/anie.200461657  1
2004 Felding-Habermann B, Lerner RA, Lillo A, Zhuang S, Weber MR, Arrues S, Gao C, Mao S, Saven A, Janda KD. Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. 101: 17210-5. PMID 15563590 DOI: 10.1073/pnas.0407869101  1
2004 Li LS, Rader C, Matsushita M, Das S, Barbas CF, Lerner RA, Sinha SC. Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices. Journal of Medicinal Chemistry. 47: 5630-40. PMID 15509162 DOI: 10.1021/jm049666k  1
2004 Zhu X, Tanaka F, Hu Y, Heine A, Fuller R, Zhong G, Olson AJ, Lerner RA, Barbas CF, Wilson IA. The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis. Journal of Molecular Biology. 343: 1269-80. PMID 15491612 DOI: 10.1016/j.jmb.2004.08.102  1
2004 Sinha SC, Li LS, Watanabe S, Kaltgrad E, Tanaka F, Rader C, Lerner RA, Barbas CF. Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 5467-72. PMID 15378729 DOI: 10.1002/chem.200400419  1
2004 Nyffeler PT, Boyle NA, Eltepu L, Wong CH, Eschenmoser A, Lerner RA, Wentworth P. Dihydrogen trioxide (HOOOH) is generated during the thermal reaction between hydrogen peroxide and ozone. Angewandte Chemie (International Ed. in English). 43: 4656-9. PMID 15317003 DOI: 10.1002/anie.200460457  1
2004 Krivacic RT, Ladanyi A, Curry DN, Hsieh HB, Kuhn P, Bergsrud DE, Kepros JF, Barbera T, Ho MY, Chen LB, Lerner RA, Bruce RH. A rare-cell detector for cancer. Proceedings of the National Academy of Sciences of the United States of America. 101: 10501-4. PMID 15249663 DOI: 10.1073/pnas.0404036101  1
2004 Torres FE, Kuhn P, De Bruyker D, Bell AG, Wolkin MV, Peeters E, Williamson JR, Anderson GB, Schmitz GP, Recht MI, Schweizer S, Scott LG, Ho JH, Elrod SA, Schultz PG, ... Lerner RA, et al. Enthalpy arrays. Proceedings of the National Academy of Sciences of the United States of America. 101: 9517-22. PMID 15210951 DOI: 10.1073/pnas.0403573101  1
2004 Tanaka F, Flores F, Kubitz D, Lerner RA, Barbas CF. Antibody-catalyzed aminolysis of a chloropyrimidine derivative. Chemical Communications (Cambridge, England). 1242-3. PMID 15136858 DOI: 10.1039/b403672g  1
2004 Zhang Q, Powers ET, Nieva J, Huff ME, Dendle MA, Bieschke J, Glabe CG, Eschenmoser A, Wentworth P, Lerner RA, Kelly JW. Metabolite-initiated protein misfolding may trigger Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 4752-7. PMID 15034169 DOI: 10.1073/pnas.0400924101  1
2004 Zhu X, Wentworth P, Wentworth AD, Eschenmoser A, Lerner RA, Wilson IA. Probing the antibody-catalyzed water-oxidation pathway at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 101: 2247-52. PMID 14982995 DOI: 10.1073/pnas.0307311101  1
2004 Sinha SC, Li LS, Miller GP, Dutta S, Rader C, Lerner RA. Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab. Proceedings of the National Academy of Sciences of the United States of America. 101: 3095-9. PMID 14981258 DOI: 10.1073/pnas.0307319101  1
2004 Tanaka F, Fuller R, Shim H, Lerner RA, Barbas CF. Evolution of aldolase antibodies in vitro: correlation of catalytic activity and reaction-based selection. Journal of Molecular Biology. 335: 1007-18. PMID 14698295 DOI: 10.1016/j.jmb.2003.11.014  1
2003 Matsushita M, Yoshida K, Yamamoto N, Wirsching P, Lerner RA, Janda KD. High-throughput screening by using a blue-fluorescent antibody sensor. Angewandte Chemie (International Ed. in English). 42: 5984-7. PMID 14679549 DOI: 10.1002/anie.200352793  1
2003 Wentworth P, Nieva J, Takeuchi C, Galve R, Wentworth AD, Dilley RB, DeLaria GA, Saven A, Babior BM, Janda KD, Eschenmoser A, Lerner RA. Evidence for ozone formation in human atherosclerotic arteries. Science (New York, N.Y.). 302: 1053-6. PMID 14605372 DOI: 10.1126/science.1089525  1
2003 Rader C, Turner JM, Heine A, Shabat D, Sinha SC, Wilson IA, Lerner RA, Barbas CF. A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy. Journal of Molecular Biology. 332: 889-99. PMID 12972259 DOI: 10.1016/S0022-2836(03)00992-6  1
2003 Hast R, Hellström-Lindberg E, Ohm L, Björkholm M, Celsing F, Dahl IM, Dybedal I, Gahrton G, Lindberg G, Lerner R, Linder O, Löfvenberg E, Nilsson-Ehle H, Paul C, Samuelsson J, et al. No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: Better outcome in patients with less proliferative disease Leukemia. 17: 1827-1833. PMID 12970783 DOI: 10.1038/sj.leu.2403035  1
2003 Rader C, Sinha SC, Popkov M, Lerner RA, Barbas CF. Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst. Proceedings of the National Academy of Sciences of the United States of America. 100: 5396-400. PMID 12702756 DOI: 10.1073/pnas.0931308100  1
2003 Lerner RA, Eschenmoser A. Ozone in biology. Proceedings of the National Academy of Sciences of the United States of America. 100: 3013-5. PMID 12631693 DOI: 10.1073/pnas.0730791100  1
2003 Wentworth P, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens. Proceedings of the National Academy of Sciences of the United States of America. 100: 1490-3. PMID 12576548 DOI: 10.1073/pnas.0437831100  1
2003 Mayfield SP, Franklin SE, Lerner RA. Expression and assembly of a fully active antibody in algae. Proceedings of the National Academy of Sciences of the United States of America. 100: 438-42. PMID 12522151 DOI: 10.1073/pnas.0237108100  1
2002 Schultz PG, Yin J, Lerner RA. The chemistry of the antibody molecule. Angewandte Chemie (International Ed. in English). 41: 4427-37. PMID 12458503 DOI: 10.1002/1521-3773(20021202)41:23<4427::AID-ANIE4427>3.0.CO;2-K  1
2002 Jones LH, Altobell LJ, MacDonald MT, Boyle NA, Wentworth P, Lerner RA, Janda KD. Active immunization with a glycolipid transition state analogue protects against endotoxic shock. Angewandte Chemie (International Ed. in English). 41: 4241-4. PMID 12434351 DOI: 10.1002/1521-3773(20021115)41:22<4241::AID-ANIE4241>3.0.CO;2-N  1
2002 Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science (New York, N.Y.). 298: 2195-9. PMID 12434011 DOI: 10.1126/science.1077642  1
2002 Gao C, Mao S, Ditzel HJ, Farnaes L, Wirsching P, Lerner RA, Janda KD. A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library. Bioorganic & Medicinal Chemistry. 10: 4057-65. PMID 12413859 DOI: 10.1016/S0968-0896(02)00340-1  1
2002 Turner JM, Larsen NA, Basran A, Barbas CF, Bruce NC, Wilson IA, Lerner RA. Biochemical characterization and structural analysis of a highly proficient cocaine esterase. Biochemistry. 41: 12297-307. PMID 12369817 DOI: 10.1021/bi026131p  1
2002 Gao C, Mao S, Kaufmann G, Wirsching P, Lerner RA, Janda KD. A method for the generation of combinatorial antibody libraries using pIX phage display. Proceedings of the National Academy of Sciences of the United States of America. 99: 12612-6. PMID 12239343 DOI: 10.1073/pnas.192467999  1
2002 Schultz PG, Lerner RA. Completing the circle. Nature. 418: 485. PMID 12152057 DOI: 10.1038/418485a  1
2002 Larsen NA, Turner JM, Stevens J, Rosser SJ, Basran A, Lerner RA, Bruce NC, Wilson IA. Crystal structure of a bacterial cocaine esterase. Nature Structural Biology. 9: 17-21. PMID 11742345 DOI: 10.1038/nsb742  1
2001 Sinha SC, Sun J, Wartmann M, Lerner RA. Synthesis of epothilone analogues by antibody-catalyzed resolution of thiazole aldol synthons on a multigram scale. Biological consequences of C-13 alkylation of epothilones. Chembiochem : a European Journal of Chemical Biology. 2: 656-65. PMID 11828502 DOI: 10.1002/1439-7633(20010903)2:9<656::AID-CBIC656>3.0.CO;2-3  1
2001 Larsen NA, Heine A, Crane L, Cravatt BF, Lerner RA, Wilson IA. Structural basis for a disfavored elimination reaction in catalytic antibody 1D4. Journal of Molecular Biology. 314: 93-102. PMID 11724535 DOI: 10.1006/jmbi.2001.5112  1
2001 Worrall DS, McDunn JE, List B, Reichart D, Hevener A, Gustafson T, Barbas CF, Lerner RA, Olefsky JM. Synthesis of an organoinsulin molecule that can be activated by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 98: 13514-8. PMID 11707596 DOI: 10.1073/pnas.241516698  1
2001 Tanaka F, Kerwin L, Kubitz D, Lerner RA, Barbas CF. Visualizing antibody-catalyzed retro-aldol-retro-Michael reactions. Bioorganic & Medicinal Chemistry Letters. 11: 2983-6. PMID 11677141 DOI: 10.1016/S0960-894X(01)00605-9  1
2001 Subauste MC, List B, Guan X, Hahn KM, Lerner R, Gilula NB. A catalytic antibody produces fluorescent tracers of gap junction communication in living cells. The Journal of Biological Chemistry. 276: 49164-8. PMID 11606573 DOI: 10.1074/jbc.M105700200  1
2001 Wentworth P, Jones LH, Wentworth AD, Zhu X, Larsen NA, Wilson IA, Xu X, Goddard WA, Janda KD, Eschenmoser A, Lerner RA. Antibody catalysis of the oxidation of water. Science (New York, N.Y.). 293: 1806-11. PMID 11546867 DOI: 10.1126/science.1062722  1
2001 Jones LH, Harwig CW, Wentworth P, Simeonov A, Wentworth AD, Py S, Ashley JA, Lerner RA, Janda KD. Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: implications for an alternative enediyne therapeutic mechanism. Journal of the American Chemical Society. 123: 3607-8. PMID 11472138 DOI: 10.1021/ja005864z  1
2001 Shabat D, Lode HN, Pertl U, Reisfeld RA, Rader C, Lerner RA, Barbas CF. In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. 98: 7528-33. PMID 11404472 DOI: 10.1073/pnas.131187998  1
2001 Sinha SC, Sun J, Miller GP, Wartmann M, Lerner RA. Catalytic antibody route to the naturally occurring epothilones: total synthesis of epothilones A-F. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 1691-702. PMID 11349910 DOI: 10.1002/1521-3765(20010417)7:8<1691::AID-CHEM16910>3.0.CO;2-9  1
2001 Chen DW, Beuscher AE, Stevens RC, Wirsching P, Lerner RA, Janda KD. Preparation of stilbene-tethered nonnatural nucleosides for use with blue-fluorescent antibodies. The Journal of Organic Chemistry. 66: 1725-32. PMID 11262119 DOI: 10.1021/jo001676f  1
2000 Simeonov A, Matsushita M, Juban EA, Thompson EH, Hoffman TZ, Beuscher AE, Taylor MJ, Wirsching P, Rettig W, McCusker JK, Stevens RC, Millar DP, Schultz PG, Lerner RA, Janda KD. Blue-fluorescent antibodies. Science (New York, N.Y.). 290: 307-13. PMID 11030644 DOI: 10.1126/science.290.5490.307  1
2000 Wentworth AD, Jones LH, Wentworth P, Janda KD, Lerner RA. Antibodies have the intrinsic capacity to destroy antigens. Proceedings of the National Academy of Sciences of the United States of America. 97: 10930-5. PMID 11005865  1
2000 Turner JM, Bui T, Lerner RA, Barbas CF, List B. An efficient benchtop system for multigram-scale kinetic resolutions using aldolase antibodies. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 2772-4. PMID 10985725 DOI: 10.1002/1521-3765(20000804)6:15<2772::AID-CHEM2772>3.0.CO;2-J  1
2000 Hasserodt J, Janda KD, Lerner RA. A class of 4-aza-lithocholic acid-derived haptens for the generation of catalytic antibodies with steroid synthase capabilities. Bioorganic & Medicinal Chemistry. 8: 995-1003. PMID 10882011 DOI: 10.1016/S0968-0896(00)00036-5  1
2000 Karlstrom A, Zhong G, Rader C, Larsen NA, Heine A, Fuller R, List B, Tanaka F, Wilson IA, Barbas CF, Lerner RA. Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task. Proceedings of the National Academy of Sciences of the United States of America. 97: 3878-83. PMID 10760259 DOI: 10.1073/pnas.97.8.3878  1
2000 Ly DH, Lockhart DJ, Lerner RA, Schultz PG. Mitotic misregulation and human aging. Science (New York, N.Y.). 287: 2486-92. PMID 10741968 DOI: 10.1126/science.287.5462.2486  1
2000 List B, Lerner RA, Barbas CF. Proline-catalyzed direct asymmetric aldol reactions [13] Journal of the American Chemical Society. 122: 2395-2396. DOI: 10.1021/ja994280y  1
2000 Hasserodt J, Janda KD, Lerner RA. Antibodies mimic natural oxidosqualene-cyclase action in steroid ring a formation Journal of the American Chemical Society. 122: 40-45. DOI: 10.1021/ja993054l  1
2000 Tanaka F, Lerner RA, Barbas CF. Reconstructing aldolase antibodies to alter their substrate specificity and turnover Journal of the American Chemical Society. 122: 4835-4836. DOI: 10.1021/ja0005441  1
2000 List B, Lerner RA, Barbas CF, Bahmanyar S, Notz W, Houk KN. Proline-catalyzed direct asymmetric aldol reactions catalytic asymmetric synthesis of anti-1,2-diols Chemtracts. 13: 904-911.  1
1999 Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD, Christianson DW. Convergence of Catalytic Antibody and Terpene Cyclase Mechanisms: Polyene Cyclization Directed by Carbocation-π Interactions. Angewandte Chemie (International Ed. in English). 38: 1743-1747. PMID 29711206 DOI: 10.1002/(SICI)1521-3773(19990614)38:12<1743::AID-ANIE1743>3.0.CO;2-3  0.68
1999 Sinha SC, Sun J, Miller G, Barbas CF, Lerner RA. Sets of aldolase antibodies with antipodal reactivities. Formal synthesis of epothilone E by large-scale antibody-catalyzed resolution of thiazole aldol. Organic Letters. 1: 1623-6. PMID 10836025  1
1999 List B, Lerner RA, Barbas CF. Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2. Organic Letters. 1: 59-61. PMID 10822533  1
1999 Zhong G, Lerner RA, Barbas III. Broadening the Aldolase Catalytic Antibody Repertoire by Combining Reactive Immunization and Transition State Theory: New Enantio- and Diastereoselectivities. Angewandte Chemie (International Ed. in English). 38: 3738-3741. PMID 10649343 DOI: 10.1002/(SICI)1521-3773(19991216)38:24<3738::AID-ANIE3738>3.0.CO;2-2  1
1999 Lerner RA, Glassock RJ, Dixon FJ. The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. Journal of the American Society of Nephrology : Jasn. 10: 1389-404. PMID 10361879  1
1999 Shabat D, Rader C, List B, Lerner RA, Barbas CF. Multiple event activation of a generic prodrug trigger by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 96: 6925-30. PMID 10359815 DOI: 10.1073/pnas.96.12.6925  1
1999 Gruber K, Zhou B, Houk KN, Lerner RA, Shevlin CG, Wilson IA. Structural basis for antibody catalysis of a disfavored ring closure reaction. Biochemistry. 38: 7062-74. PMID 10353817 DOI: 10.1021/bi990210s  1
1999 Gao C, Mao S, Lo CH, Wirsching P, Lerner RA, Janda KD. Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays. Proceedings of the National Academy of Sciences of the United States of America. 96: 6025-30. PMID 10339535 DOI: 10.1073/pnas.96.11.6025  1
1999 List B, Shabat D, Zhong G, Turner JM, Li A, Bui T, Anderson J, Lerner RA, Barbas CF. A catalytic enantioselective route to hydroxy-substituted quaternary carbon centers: Resolution of tertiary aldols with a catalytic antibody Journal of the American Chemical Society. 121: 7283-7291. DOI: 10.1021/ja991507g  1
1999 Tanaka F, Almer H, Lerner RA, Barbas CF. Catalytic single-chain antibodies possessing β-lactamase activity selected from a phage displayed combinatorial library using a mechanism-based inhibitor Tetrahedron Letters. 40: 8063-8066. DOI: 10.1016/S0040-4039(99)01695-0  1
1999 Shabat D, List B, Lerner RA, Barbas CF. A short enantioselective synthesis of 1-deoxy-L-xylulose by antibody catalysis Tetrahedron Letters. 40: 1437-1440. DOI: 10.1016/S0040-4039(98)02699-9  1
1999 Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD, Christianson DW. Convergence of catalytic antibody and terpene cyclase mechanisms: Polyene cyclization directed by carbocation - π interactions Angewandte Chemie - International Edition. 38: 1743-1747. DOI: 10.1002/(SICI)1521-3773(19990614)38:12<1743::AID-ANIE1743>3.0.CO;2-3  1
1999 Taylor MJ, Yli-Kauhaluoma JT, Ashley JA, Wirsching P, Lerner RA, Janda KD. The α-ketoamide group: A new motif for the elicitation of catalytic antibodies for acyl-transfer reactions Journal of the Chemical Society - Perkin Transactions 1. 1133-1134.  1
1999 Tanaka F, Lerner RA, Barbas CF. Thiazolium-dependent catalytic antibodies produced using a covalent modification strategy Chemical Communications. 1383-1384.  1
1998 Zhong G, Shabat D, List B, Anderson J, Sinha SC, Lerner RA, Barbas Iii CF. Catalytic Enantioselective Retro-Aldol Reactions: Kinetic Resolution of β-Hydroxyketones with Aldolase Antibodies. Angewandte Chemie (International Ed. in English). 37: 2481-2484. PMID 29711357 DOI: 10.1002/(SICI)1521-3773(19981002)37:18<2481::AID-ANIE2481>3.0.CO;2-T  0.88
1998 List B, Barbas CF, Lerner RA. Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 95: 15351-5. PMID 9860972 DOI: 10.1073/pnas.95.26.15351  1
1998 Sinha SC, Barbas CF, Lerner RA. The antibody catalysis route to the total synthesis of epothilones. Proceedings of the National Academy of Sciences of the United States of America. 95: 14603-8. PMID 9843936 DOI: 10.1073/pnas.95.25.14603  1
1998 Boger DL, Patterson JE, Guan X, Cravatt BF, Lerner RA, Gilula NB. Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. Proceedings of the National Academy of Sciences of the United States of America. 95: 4810-5. PMID 9560184 DOI: 10.1073/pnas.95.9.4810  1
1998 Taylor MJ, Hoffman TZ, Yli-Kauhaluoma JT, Lerner RA, Janda KD. A light-activated antibody catalyst Journal of the American Chemical Society. 120: 12783-12790. DOI: 10.1021/ja982711r  1
1998 Hoffmann T, Zhong G, List B, Shabat D, Anderson J, Gramatikova S, Lerner RA, Barbas CF. Aldolase antibodies of remarkable scope Journal of the American Chemical Society. 120: 2768-2779. DOI: 10.1021/ja973676b  1
1998 Zhong G, Shabat D, List B, Anderson J, Sinha SC, Lerner RA, Barbas CF. Catalytic enantioselective retro-aldol reactions: Kinetic resolution of β-hydroxyketones with aldolase antibodies Angewandte Chemie - International Edition. 37: 2481-2484. DOI: 10.1002/(SICI)1521-3773(19981002)37:18<2481::AID-ANIE2481>3.0.CO;2-T  1
1998 List B, Shabat D, Barbas CF, Lerner RA. Enantioselective total synthesis of some brevicomins using aldolase antibody 38C2 Chemistry - a European Journal. 4: 881-885. DOI: 10.1002/(SICI)1521-3765(19980515)4:5<881::AID-CHEM881>3.0.CO;2-#  1
1997 Guan X, Cravatt BF, Ehring GR, Hall JE, Boger DL, Lerner RA, Gilula NB. The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. The Journal of Cell Biology. 139: 1785-92. PMID 9412472 DOI: 10.1083/jcb.139.7.1785  1
1997 Barbas CF, Heine A, Zhong G, Hoffmann T, Gramatikova S, Björnestedt R, List B, Anderson J, Stura EA, Wilson IA, Lerner RA. Immune versus natural selection: antibody aldolases with enzymic rates but broader scope. Science (New York, N.Y.). 278: 2085-92. PMID 9405338 DOI: 10.1126/science.278.5346.2085  1
1997 Lerner RA. A hypothesis about the endogenous analogue of general anesthesia. Proceedings of the National Academy of Sciences of the United States of America. 94: 13375-7. PMID 9391028 DOI: 10.1073/pnas.94.25.13375  1
1997 Gao C, Lin CH, Lo CH, Mao S, Wirsching P, Lerner RA, Janda KD. Making chemistry selectable by linking it to infectivity. Proceedings of the National Academy of Sciences of the United States of America. 94: 11777-82. PMID 9342313 DOI: 10.1073/pnas.94.22.11777  1
1997 Lin CH, Hoffman TZ, Wirsching P, Barbas CF, Janda KD, Lerner RA. On roads not taken in the evolution of protein catalysts: antibody steroid isomerases that use an enamine mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 11773-6. PMID 9342312 DOI: 10.1073/pnas.94.22.11773  1
1997 Janda KD, Lo LC, Lo CH, Sim MM, Wang R, Wong CH, Lerner RA. Chemical selection for catalysis in combinatorial antibody libraries. Science (New York, N.Y.). 275: 945-8. PMID 9020070 DOI: 10.1126/science.275.5302.945  1
1997 Zhong G, Hoffmann T, Lerner RA, Danishefsky S, Barbas CF. Antibody-catalyzed enantioselective Robinson annulation Journal of the American Chemical Society. 119: 8131-8132. DOI: 10.1021/ja970944x  1
1997 Hasserodt J, Janda KD, Lerner RA. Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization Journal of the American Chemical Society. 119: 5993-5998. DOI: 10.1021/ja970675a  1
1997 Schröer J, Sanner M, Reymond JL, Lerner RA. Design and Synthesis of Transition State Analogs for Induction of Hydride Transfer Catalytic Antibodies Journal of Organic Chemistry. 62: 3215-3219.  1
1997 Li T, Lerner RA, Janda KD. Antibody-Catalyzed Cationic Reactions: Rerouting of Chemical Transformations via Antibody Catalysis Accounts of Chemical Research. 30: 115-121.  1
1996 Lerner RA, Barbas 3rd. C.F. CF, Janda KD. Making enzymes Harvey Lectures. 92: 1-40. PMID 15372741  1
1996 Cravatt BF, Giang DK, Mayfield SP, Boger DL, Lerner RA, Gilula NB. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature. 384: 83-7. PMID 8900284 DOI: 10.1038/384083a0  1
1996 Wagner J, Lerner RA, Barbas CF. Synthesis of five enantiomerically pure haptens designed for in vitro evolution of antibodies with peptidase activity Bioorganic and Medicinal Chemistry. 4: 901-916. PMID 8818241 DOI: 10.1016/0968-0896(96)00085-5  1
1996 Lerner RA, Barbas CF. Using the process of reactive immunization to induce catalytic antibodies with complex mechanisms: Aldolases Acta Chemica Scandinavica. 50: 672-678. PMID 8756355  1
1996 Rosenblum JS, Gilula NB, Lerner RA. On signal sequence polymorphisms and diseases of distribution Proceedings of the National Academy of Sciences of the United States of America. 93: 4471-4473. PMID 8633092 DOI: 10.1073/pnas.93.9.4471  1
1996 Li T, Janda KD, Lerner RA. Cationic cyclopropanation by antibody catalysis Nature. 379: 326-327. PMID 8552185 DOI: 10.1038/379326a0  1
1996 Björnestedt R, Zhong G, Lerner RA, Barbas CF. Copying nature's mechanism for the decarboxylation of β-keto acids into catalytic antibodies by reactive immunization Journal of the American Chemical Society. 118: 11720-11724. DOI: 10.1021/ja9620797  1
1996 Hasserodt J, Janda KD, Lerner RA. Antibody catalyzed terpenoid cyclization Journal of the American Chemical Society. 118: 11654-11655. DOI: 10.1021/ja954316w  1
1996 Patterson JE, Ollmann IR, Cravatt BF, Boger DL, Wong CH, Lerner RA. Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide Journal of the American Chemical Society. 118: 5938-5945. DOI: 10.1021/ja954064z  1
1996 Bahr N, Güller R, Reymond JL, Lerner RA. A nitroxyl synthase catalytic antibody Journal of the American Chemical Society. 118: 3550-3555. DOI: 10.1021/ja9538694  1
1996 Cravatt BF, Lerner RA, Boger DL. Structure determination of an endogenous sleep-inducing lipid, cis-9-octadecenamide (oleamide): A synthetic approach to the chemical analysis of trace quantities of a natural product Journal of the American Chemical Society. 118: 580-590. DOI: 10.1021/ja9532345  1
1996 Keinan E, Lerner RA. The first decade of antibody catalysis: Perspective and prospects Israel Journal of Chemistry. 36: 113-119.  1
1996 Lo CHL, Gao C, Mao S, Matsui K, Lerner RA, Janda KD. Chain shuffling: Investigations into the specificity and selectivity of antibody catalysis Israel Journal of Chemistry. 36: 195-198.  1
1995 Wagner J, Lerner RA, Barbas CF. Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes Science. 270: 1797-1800. PMID 8525368  1
1995 Wirsching P, Ashley JA, Lo CHL, Janda KD, Lerner RA. Reactive immunization Science. 270: 1775-1782. PMID 8525366  1
1995 Fenniri H, Janda KD, Lerner RA. Encoded reaction cassette for the highly sensitive detection of the making and breaking of chemical bonds Proceedings of the National Academy of Sciences of the United States of America. 92: 2278-2282. PMID 7892261 DOI: 10.1073/pnas.92.6.2278  1
1995 Lerner RA, Guillemin R. Floyd Bloom: the next editor-in-chief of Science. Science (New York, N.Y.). 267: 1441-2. PMID 7878461  1
1995 Lerner RA. The care and feeding of structural biologists Faseb Journal. 9: 1. PMID 7821747  1
1995 Cravatt BF, Prospero-Garcia O, Siuzdak G, Gilula NB, Henriksen SJ, Boger DL, Lerner RA. Chemical characterization of a family of brain lipids that induce sleep. Science (New York, N.Y.). 268: 1506-9. PMID 7770779  1
1995 Light J, Lerner RA. Random mutagenesis of staphylococcal nuclease and phage display selection Bioorganic and Medicinal Chemistry. 3: 955-967. PMID 7582973 DOI: 10.1016/0968-0896(95)00075-R  1
1995 Lerner RA, Janda KD. Catalytic antibodies: evolution of protein function in real time Exs. 73: 121-138. PMID 7579971  1
1995 Schultz PG, Lerner RA. From molecular diversity to catalysis: Lessons from the immune system Science. 269: 1835-1842. PMID 7569920  1
1995 Janda KD, Shevlin CG, Lerner RA. Oxepane synthesis along a disfavored pathway: The rerouting of a chemical reaction using a catalytic antibody Journal of the American Chemical Society. 117: 2659-2660. DOI: 10.1021/ja00114a035  1
1995 Rosenblum JS, Lo LC, Li T, Janda KD, Lerner RA. Antibody-catalyzed phosphate triester hydrolysis Angewandte Chemie (International Edition in English). 34: 2275-2277.  1
1995 Koch T, Reymond JL, Lerner RA. Antibody catalysis of multistep reactions: An aldol addition followed by a disfavored elimination Journal of the American Chemical Society. 117: X-9387.  1
1995 Li T, Janda KD, Hilton S, Lerner RA. An antibody-catalyzed nucleophilic substitution reaction at a primary carbon that appears to proceed by an ionization mechanism Journal of the American Chemical Society. 117: 2367-2368.  1
1995 Koch T, Reymond JL, Lerner RA. Antibody catalysis of multistep reaction: An aldol addition followed by a disfavored elimination Journal of the American Chemical Society. 117: 9383-9387.  1
1994 Li T, Janda KD, Ashley JA, Lerner RA. Antibody catalyzed cationic cyclization Science. 264: 1289-1293. PMID 8191282  1
1994 Janda KD, Lo CHL, Li T, Barbas CF, Wirsching P, Lerner RA. Direct selection for a catalytic mechanism from combinatorial antibody libraries Proceedings of the National Academy of Sciences of the United States of America. 91: 2532-2536. PMID 8146149  1
1994 Lerner RA, Siuzdak G, Prospero-Garcia O, Henriksen SJ, Boger DL, Cravatt BF. Cerebrodiene: a brain lipid isolated from sleep-deprived cats. Proceedings of the National Academy of Sciences of the United States of America. 91: 9505-8. PMID 7937797  1
1994 Reymond JL, Reber JL, Lerner RA. Enantioselective, multigram-scale synthesis with a catalytic antibody Angewandte Chemie (International Edition in English). 33: 475-477.  1
1994 Boger DL, Lerner RA, Cravatt BF. Synthesis of a functionalized rigid bicyclo[2.2.1]heptane: A useful hapten for eliciting catalytic antibodies Journal of Organic Chemistry. 59: 5078-5079.  1
1994 Chen Y, Reymond JL, Lerner RA. An antibody-catalyzed 1,2-rearrangement of carbon - Carbon bonds Angewandte Chemie (International Edition in English). 33: 1607-1609.  1
1994 Cravatt BF, Ashley JA, Janda KD, Boger DL, Lerner RA. Crossing extreme mechanistic barriers by antibody catalysis: Syn elimination to a cis olefin Journal of the American Chemical Society. 116: 6013-6014.  1
1993 Janda KD, Shevlin CG, Lerner RA. Antibody catalysis of a disfavored chemical transformation Science. 259: 490-493. PMID 8424171  1
1993 Barbas CF, Rosenblum JS, Lerner RA. Direct selection of antibodies that coordinate metals from semisynthetic combinatorial libraries Proceedings of the National Academy of Sciences of the United States of America. 90: 6385-6389. PMID 8341642  1
1993 Lerner RA. Catalytic antibodies: The concept and the promise Hospital Practice. 28: 53-59. PMID 8325916  1
1993 Barbas CF, Amberg W, Simoncsits A, Jones TM, Lerner RA. Selection of human anti-hapten antibodies from semisynthetic libraries Gene. 137: 57-62. PMID 8282201 DOI: 10.1016/0378-1119(93)90251-W  1
1993 Gouverneur VE, Houk KN, de Pascual-Teresa B, Beno B, Janda KD, Lerner RA. Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis. Science (New York, N.Y.). 262: 204-8. PMID 8211138  1
1993 Wade WS, Koh JS, Han N, Hoekstra DM, Lerner RA. Engineering metal coordination sites into the antibody light chain Journal of the American Chemical Society. 115: 4449-4456.  1
1993 Jack Chen YC, Danon T, Sastry L, Mubaraki M, Janda KD, Lerner RA. Catalytic antibodies from combinatorial libraries Journal of the American Chemical Society. 115: 357-358.  1
1993 Schultz PG, Lerner RA. Antibody catalysis of difficult chemical transformations Accounts of Chemical Research. 26: 391-395.  1
1993 Wade WS, Ashley JA, Jahangiri GK, McElhaney G, Janda KD, Lerner RA. A highly specific metal-activated catalytic antibody Journal of the American Chemical Society. 115: 4906-4907.  1
1993 Na J, Houk KN, Shevlin CG, Janda KD, Lerner RA. The energetic advantage of 5-exo versus 6-endo epoxide openings: A preference overwhelmed by antibody catalysis Journal of the American Chemical Society. 115: 8453-8454.  1
1993 Reymond JL, Jahangiri GK, Stoudt C, Lerner RA. Antibody catalyzed hydrolysis of enol ethers Journal of the American Chemical Society. 115: 3909-3917.  1
1992 Jane Dyson H, Norrby E, Hoey K, Elliot Parks D, Lerner RA, Wright PE. Immunogenic peptides corresponding to the dominant antigenic region alanine-597 to cysteine-619 in the transmembrane protein of simian immunodeficiency virus have a propensity to fold in aqueous solution Biochemistry®. 31: 1458-1463. PMID 1737004  1
1992 Brenner S, Lerner RA. Encoded combinatorial chemistry Proceedings of the National Academy of Sciences of the United States of America. 89: 5381-5383. PMID 1608946 DOI: 10.1073/pnas.89.12.5381  1
1992 Barbas CF, Bain JD, Hoekstra DM, Lerner RA. Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem. Proceedings of the National Academy of Sciences of the United States of America. 89: 4457-61. PMID 1584777 DOI: 10.1073/pnas.89.10.4457  1
1992 Gram H, Marconi LA, Barbas CF, Collet TA, Lerner RA, Kang AS. In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library Proceedings of the National Academy of Sciences of the United States of America. 89: 3576-3580. PMID 1565653  1
1992 Dyson HJ, Sayre JR, Merutka G, Shin HC, Lerner RA, Wright PE. Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding II. Plastocyanin Journal of Molecular Biology. 226: 819-835. PMID 1507228 DOI: 10.1016/0022-2836(92)90634-V  1
1992 Dyson HJ, Merutka G, Waltho JP, Lerner RA, Wright PE. Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding I. Myohemerythrin Journal of Molecular Biology. 226: 795-817. PMID 1507227 DOI: 10.1016/0022-2836(92)90633-U  1
1992 Lerner RA, Kang AS, Bain JD, Burton DR, Barbas CF. Antibodies without immunization. Science (New York, N.Y.). 258: 1313-4. PMID 1455226  1
1992 Collet TA, Roben P, O'Kennedy R, Barbas CF, Burton DR, Lerner RA. A binary plasmid system for shuffling combinatorial antibody libraries Proceedings of the National Academy of Sciences of the United States of America. 89: 10026-10030. PMID 1438192  1
1992 Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. 1989. Biotechnology (Reading, Mass.). 24: 517-23. PMID 1422064  1
1992 Tsang P, Rance M, Fieser TM, Ostresh JM, Houghten RA, Lerner RA, Wright PE. Conformation and dynamics of an Fab′-bound peptide by isotope-edited NMR spectroscopy Biochemistry. 31: 3862-3871. PMID 1373648  1
1992 Alexander H, Alexander S, Getzoff ED, Tainer JA, Geysen HM, Lerner RA. Altering the antigenicity of proteins Proceedings of the National Academy of Sciences of the United States of America. 89: 3352-3356. PMID 1373498  1
1992 Zebedee SL, Barbas CF, Hom YL, Caothien RH, Graff R, DeGraw J, Pyati J, LaPolla R, Burton DR, Lerner RA, Thornton GB. Human combinatorial antibody libraries to hepatitis B surface antigen Proceedings of the National Academy of Sciences of the United States of America. 89: 3175-3179. PMID 1373487  1
1992 Light J, Lerner RA. Phophabs: Antibody-phage-alkaline phosphatase conjugates for one step ELISA's without immunization Bioorganic and Medicinal Chemistry Letters. 2: 1073-1078. DOI: 10.1016/S0960-894X(00)80621-6  1
1992 Barbas CF, Bain JD, Hoekstra DM, Lerner RA. Semisynthetic combinatorial antibody libraries: A chemical solution to the diversity problem Proceedings of the National Academy of Sciences of the United States of America. 89: 4452-4456.  1
1992 Gibbs RA, Benkovic PA, Janda KD, Lerner RA, Benkovic SJ. Substituent effects on an antibody-catalyzed hydrolysis of phenyl esters: Further evidence for an acyl-antibody intermediate Journal of the American Chemical Society. 114: 3528-3534.  1
1992 Fernholz E, Schloeder D, Liu KKC, Bradshaw CW, Huang H, Janda K, Lerner RA, Wong CH. Specificity of antibody-catalyzed transesterifications using enol esters: A comparison with lipase reactions Journal of Organic Chemistry. 57: 4756-4761.  1
1991 Iverson BL, Iverson SA, Cameron KE, Jahangiri GK, Pasternak DS, Lerner RA. Tritylase antibodies. Ciba Foundation Symposium. 159: 227-33; discussion 2. PMID 1959450  1
1991 Sastry L, Mubaraki M, Janda KD, Benkovic SJ, Lerner RA. Screening combinatorial antibody libraries for catalytic acyl transfer reactions. Ciba Foundation Symposium. 159: 145-51; discussion 1. PMID 1835693  1
1990 Roberts VA, Iverson BL, Iverson SA, Benkovic SJ, Lerner RA, Getzoff ED, Tainer JA. Antibody remodeling: a general solution to the design of a metal-coordination site in an antibody binding pocket. Proceedings of the National Academy of Sciences of the United States of America. 87: 6654-8. PMID 2395868  1
1990 Iverson BL, Iverson SA, Roberts VA, Getzoff ED, Tainer JA, Benkovic SJ, Lerner RA. Metalloantibodies. Science (New York, N.Y.). 249: 659-62. PMID 2116666  1
1989 Iverson BL, Lerner RA. Sequence-specific peptide cleavage catalyzed by an antibody. Science (New York, N.Y.). 243: 1184-8. PMID 2922606  1
1989 Iverson SA, Sastry L, Huse WD, Sorge JA, Benkovic SJ, Lerner RA. A combinatorial system for cloning and expressing the catalytic antibody repertoire in Escherichia coli. Cold Spring Harbor Symposia On Quantitative Biology. 54: 273-81. PMID 2700937  1
1989 Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science (New York, N.Y.). 246: 1275-81. PMID 2531466  1
1989 Sastry L, Alting-Mees M, Huse WD, Short JM, Sorge JA, Hay BN, Janda KD, Benkovic SJ, Lerner RA. Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library. Proceedings of the National Academy of Sciences of the United States of America. 86: 5728-32. PMID 2503822  1
1984 Milner RJ, Bloom FE, Lai C, Lerner RA, Sutcliffe JG. Brain-specific genes have identifier sequences in their introns. Proceedings of the National Academy of Sciences of the United States of America. 81: 713-7. PMID 6583673  1
1984 Shinnick TM, Sutcliffe JG, Green N, Lerner RA. Peptide-elicited protein-reactive antibodies in molecular biology and medicine. The Journal of Investigative Dermatology. 83: 112s-115s. PMID 6376645  1
1984 Macfarlan RI, Dietzschold B, Wiktor TJ, Kiel M, Houghten R, Lerner RA, Sutcliffe JG, Koprowski H. T cell responses to cleaved rabies virus glycoprotein and to synthetic peptides. Journal of Immunology (Baltimore, Md. : 1950). 133: 2748-52. PMID 6332859  1
1984 Sutcliffe JG, Milner RJ, Gottesfeld JM, Lerner RA. Identifier sequences are transcribed specifically in brain. Nature. 308: 237-41. PMID 6199680 DOI: 10.1038/308237a0  1
1983 Shinnick TM, Sutcliffe JG, Green N, Lerner RA. Synthetic peptide immunogens as vaccines. Annual Review of Microbiology. 37: 425-46. PMID 6357058 DOI: 10.1146/annurev.mi.37.100183.002233  1
1983 Gerin JL, Alexander H, Shih JW, Purcell RH, Dapolito G, Engle R, Green N, Sutcliffe JG, Shinnick TM, Lerner RA. Chemically synthesized peptides of hepatitis B surface antigen duplicate the d/y specificities and induce subtype-specific antibodies in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 80: 2365-9. PMID 6188163  1
1983 Sutcliffe JG, Shinnick TM, Green N, Lerner RA. Antibodies that react with predetermined sites on proteins. Science (New York, N.Y.). 219: 660-6. PMID 6186024  1
1982 Bittle JL, Houghten RA, Alexander H, Shinnick TM, Sutcliffe JG, Lerner RA, Rowlands DJ, Brown F. Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence. Nature. 298: 30-3. PMID 7045684 DOI: 10.1038/298030a0  1
1982 Sutcliffe JG, Milner RJ, Bloom FE, Lerner RA. Common 82-nucleotide sequence unique to brain RNA. Proceedings of the National Academy of Sciences of the United States of America. 79: 4942-6. PMID 6956902  1
1982 Green N, Alexander H, Olson A, Alexander S, Shinnick TM, Sutcliffe JG, Lerner RA. Immunogenic structure of the influenza virus hemagglutinin. Cell. 28: 477-87. PMID 6176330 DOI: 10.1016/0092-8674(82)90202-1  1
1981 Lerner RA, Sutcliffe JG, Shinnick TM. Antibodies to chemically synthesized peptides predicted from DNA sequences as probes of gene expression. Cell. 23: 309-10. PMID 7008951  1
1981 Green N, Shinnick TM, Witte O, Ponticelli A, Sutcliffe JG, Lerner RA. Sequence-specific antibodies show that maturation of Moloney leukemia virus envelope polyprotein involves removal of a COOH-terminal peptide. Proceedings of the National Academy of Sciences of the United States of America. 78: 6023-7. PMID 6947213  1
1981 Sutcliffe JG, Shinnick TM, Lerner RA. Moloney murine leukemia virus is a transposon: nucleotide sequence analysis identifies genes and replication details. Cold Spring Harbor Symposia On Quantitative Biology. 45: 707-10. PMID 6266762  1
1981 Lerner RA, Green N, Olson A, Shinnick T, Sutcliffe JG. The development of synthetic vaccines. Hospital Practice (Office Ed.). 16: 55-62. PMID 6171500  1
1981 Shinnick TM, Lerner RA, Sutcliffe JG. Nucleotide sequence of Moloney murine leukaemia virus. Nature. 293: 543-8. PMID 6169994 DOI: 10.1038/293543a0  1
1981 Lerner RA, Green N, Alexander H, Liu FT, Sutcliffe JG, Shinnick TM. Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles. Proceedings of the National Academy of Sciences of the United States of America. 78: 3403-7. PMID 6167985 DOI: 10.1073/pnas.78.6.3403  1
1980 Sutcliffe JG, Shinnick TM, Verma IM, Lerner RA. Nucleotide sequence of Moloney leukemia virus: 3' end reveals details of replications, analogy to bacterial transposons, and an unexpected gene. Proceedings of the National Academy of Sciences of the United States of America. 77: 3302-6. PMID 6251454  1
1980 Sutcliffe JG, Shinnick TM, Green N, Liu FT, Niman HL, Lerner RA. Chemical synthesis of a polypeptide predicted from nucleotide sequence allows detection of a new retroviral gene product. Nature. 287: 801-5. PMID 6159543 DOI: 10.1038/287801a0  1
1980 Sutcliffe JG, Shinnick TM, Lerner RA, Johnson P, Verma IM. Nucleotide sequence of a cloned murine leukemia virus DNA fragment. Cold Spring Harbor Symposia On Quantitative Biology. 44: 1275-9. PMID 6159135  1
1976 Levy RL, Lerner RA, Dixon FJ. Enhancement of infectivity and oncogenicity of a murine leukemia virus in adult mice by X-irradiation. Cancer Research. 36: 2090-5. PMID 178443  1
1976 Lerner RA, Wilson CB, Villano BC, McConahey PJ, Dixon FJ. Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70. The Journal of Experimental Medicine. 143: 151-66. PMID 172586  1
1975 Del Vellano BC, Nave B, Croker BP, Lerner RA, Dixon FJ. The oncornavirus glycoprotein gp69/71: a constituent of the surface of normal and malignant thymocytes. The Journal of Experimental Medicine. 141: 172-87. PMID 46909  1
1974 Croker BP, del Villano BC, Jensen FC, Lerner RA, Dixon FJ. Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus. The Journal of Experimental Medicine. 140: 1028-48. PMID 4372290  1
1973 Lerner RA, Dixon FJ. The human lymphocyte as an experimental animal. Scientific American. 228: 82-91. PMID 4722236  1
1972 Lerner RA, McConahey PJ, Jansen I, Dixon FJ. Synthesis of plasma membrane-associated and secretory immunoglobulin in diploid lymphocytes. The Journal of Experimental Medicine. 135: 136-49. PMID 5061901  1
1972 Lerner RA, Jensen F, Kennel SJ, Dixon FJ, Des Roches G, Francke U. Karyotypic, virologic, and immunologic analyses of two continuous lymphocyte lines established from New Zealand black mice: possible relationship of chromosomal mosaicism to autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 69: 2965-9. PMID 4342970  1
1971 Lerner RA, McConahey PJ, Dixon FJ. Quantitative aspects of plasma membrane-associated immunoglobulin in clones of diploid human lymphocytes. Science (New York, N.Y.). 173: 60-2. PMID 5087481  1
1969 Dixon FJ, McPhaul JJ, Lerner RA. The contribution of kidney transplantation o the study of glomerulonephritis--the recurrence of glomerulonephritis in renal transplants. Transplantation Proceedings. 1: 194-6. PMID 4944217  1
1968 Lerner RA, McPhaul JJ, Dixon FJ. Soluble glomerular basement membrane antigens in normal urine--possible autoimmunogens in man. Annals of Internal Medicine. 68: 249-50. PMID 5299824  1
1968 Starzl TE, Lerner RA, Dixon FJ, Groth CG, Brettschneider L, Terasaki PI. Shwartzman reaction after human renal homotransplantation. The New England Journal of Medicine. 278: 642-8. PMID 4866352 DOI: 10.1056/NEJM196803212781202  1
1968 Lerner RA, Dixon FJ. The induction of acute glomerulonephritis in rabbits with soluble antigens isolated from normal homologous and autologous urine. Journal of Immunology (Baltimore, Md. : 1950). 100: 1277-87. PMID 4177027  1
1968 Lerner RA, Dixon FJ, Lee S. Spontaneous glomerulonephritis in sheep. II. Studies on natural history, occurrence in other species, and pathogenesis. The American Journal of Pathology. 53: 501-12. PMID 4175664  1
1967 Lerner RA, Glassock RJ, Dixon FJ. The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. The Journal of Experimental Medicine. 126: 989-1004. PMID 4964566  1
1966 Lerner RA, Dixon FJ. Spontaneous glomerulonephritis in sheep. Laboratory Investigation; a Journal of Technical Methods and Pathology. 15: 1279-89. PMID 5949954  1
1966 Lerner RA, Dixon FJ. Transfer of ovine experimental allergic glomerulonephritis (EAG) with serum. The Journal of Experimental Medicine. 124: 431-42. PMID 5922743  1
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