Chris B. Schaffer, Ph.D. - Publications

Affiliations: 
Biomedical Engineering Cornell University, Ithaca, NY, United States 
Area:
Cerebral blood flow, neurodegeneration, optical imaging, nonlinear microscopy
Website:
http://www.bme.cornell.edu/schafferlab

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang Y, Bander ED, Lee Y, Muoser C, Schaffer CB, Nishimura N. Microvessel occlusions alter amyloid-beta plaque morphology in a mouse model of Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19889092. PMID 31744388 DOI: 10.1177/0271678X19889092  1
2019 Macknik SL, Alexander RG, Caballero O, Chanovas J, Nielsen KJ, Nishimura N, Schaffer CB, Slovin H, Babayoff A, Barak R, Tang S, Ju N, Yazdan-Shahmorad A, Alonso JM, Malinskiy E, et al. Advanced Circuit and Cellular Imaging Methods in Nonhuman Primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 39: 8267-8274. PMID 31619496 DOI: 10.1523/JNEUROSCI.1168-19.2019  1
2019 Hachinski V, Einhäupl K, Ganten D, Alladi S, Brayne C, Stephan BCM, Sweeney MD, Zlokovic B, Iturria-Medina Y, Iadecola C, Nishimura N, Schaffer CB, Whitehead SN, Black SE, Østergaard L, et al. Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto. International Journal of Stroke : Official Journal of the International Stroke Society. 1747493019871915. PMID 31543058 DOI: 10.1177/1747493019871915  1
2019 Bracko O, Njiru BN, Swallow M, Ali M, Haft-Javaherian M, Schaffer CB. Increasing cerebral blood flow improves cognition into late stages in Alzheimer's disease mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19873658. PMID 31495298 DOI: 10.1177/0271678X19873658  0.48
2019 Hachinski V, Einhäupl K, Ganten D, Alladi S, Brayne C, Stephan BCM, Sweeney MD, Zlokovic B, Iturria-Medina Y, Iadecola C, Nishimura N, Schaffer CB, Whitehead SN, Black SE, Østergaard L, et al. Preventing dementia by preventing stroke: The Berlin Manifesto. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 15: 961-984. PMID 31327392 DOI: 10.1016/j.jalz.2019.06.001  1
2019 Smith AF, Doyeux V, Berg M, Peyrounette M, Haft-Javaherian M, Larue AE, Slater JH, Lauwers F, Blinder P, Tsai P, Kleinfeld D, Schaffer CB, Nishimura N, Davit Y, Lorthois S. Brain Capillary Networks Across Species: A few Simple Organizational Requirements Are Sufficient to Reproduce Both Structure and Function. Frontiers in Physiology. 10: 233. PMID 30971935 DOI: 10.3389/fphys.2019.00233  1
2019 Haft-Javaherian M, Fang L, Muse V, Schaffer CB, Nishimura N, Sabuncu MR. Deep convolutional neural networks for segmenting 3D in vivo multiphoton images of vasculature in Alzheimer disease mouse models. Plos One. 14: e0213539. PMID 30865678 DOI: 10.1371/journal.pone.0213539  1
2019 Cruz Hernández JC, Bracko O, Kersbergen CJ, Muse V, Haft-Javaherian M, Berg M, Park L, Vinarcsik LK, Ivasyk I, Rivera DA, Kang Y, Cortes-Canteli M, Peyrounette M, Doyeux V, Smith A, ... ... Schaffer CB, et al. Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models. Nature Neuroscience. PMID 30742116 DOI: 10.1038/s41593-018-0329-4  1
2019 Chan S, Brophy M, Nishimura N, Schaffer CB. Aspirin treatment does not increase microhemorrhage size in young or aged mice. Plos One. 14: e0204295. PMID 30608925 DOI: 10.1371/journal.pone.0204295  1
2018 Nagappan S, Liu L, Fetcho R, Nguyen J, Nishimura N, Radwanski RE, Lieberman S, Baird-Daniel E, Ma H, Zhao M, Schaffer CB, Schwartz TH. In Vivo Femtosecond Laser Subsurface Cortical Microtransections Attenuate Acute Rat Focal Seizures. Cerebral Cortex (New York, N.Y. : 1991). PMID 30192931 DOI: 10.1093/cercor/bhy210  1
2018 Ahn SJ, Anrather J, Nishimura N, Schaffer CB. Diverse Inflammatory Response After Cerebral Microbleeds Includes Coordinated Microglial Migration and Proliferation. Stroke. PMID 29844029 DOI: 10.1161/STROKEAHA.117.020461  1
2017 Bollu T, Cornelius NR, Sunwoo J, Nishimura N, Schaffer CB, Doerschuk PC. Experimentally constrained circuit model of cortical arteriole networks for understanding flow redistribution due to occlusion and neural activation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17741086. PMID 29130779 DOI: 10.1177/0271678X17741086  1
2016 Calvey GD, Katz AM, Schaffer CB, Pollack L. Mixing injector enables time-resolved crystallography with high hit rate at X-ray free electron lasers. Structural Dynamics (Melville, N.Y.). 3: 054301. PMID 27679802 DOI: 10.1063/1.4961971  1
2016 Koyama M, Minale F, Shum J, Nishimura N, Schaffer CB, Fetcho JR. A circuit motif in the zebrafish hindbrain for a two alternative behavioral choice to turn left or right. Elife. 5. PMID 27502742 DOI: 10.7554/eLife.16808  1
2015 Wayne EC, Chandrasekaran S, Mitchell MJ, Chan MF, Lee RE, Schaffer CB, King MR. TRAIL-coated leukocytes that prevent the bloodborne metastasis of prostate cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26732555 DOI: 10.1016/j.jconrel.2015.12.048  1
2015 Cohen R, Lata JP, Lee Y, Hernández JC, Nishimura N, Schaffer CB, Mukai C, Nelson JL, Brangman SA, Agrawal Y, Travis AJ. Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection. Plos One. 10: e0142326. PMID 26605916 DOI: 10.1371/journal.pone.0142326  1
2015 Tsai PS, Mateo C, Field JJ, Schaffer CB, Anderson ME, Kleinfeld D. Ultra-large field-of-view two-photon microscopy. Optics Express. 23: 13833-47. PMID 26072755  0.6
2015 Shih AY, Rühlmann C, Blinder P, Devor A, Drew PJ, Friedman B, Knutsen PM, Lyden PD, Matéo C, Mellander L, Nishimura N, Schaffer CB, Tsai PS, Kleinfeld D. Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture. Microcirculation (New York, N.Y. : 1994). 22: 204-18. PMID 25705966 DOI: 10.1111/micc.12195  1
2015 Farrar MJ, Rubin JD, Diago DM, Schaffer CB. Characterization of blood flow in the mouse dorsal spinal venous system before and after dorsal spinal vein occlusion. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 667-75. PMID 25564237 DOI: 10.1038/jcbfm.2014.244  1
2015 Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, et al. Vascular contributions to cognitive impairment and dementia including Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 710-717. PMID 25510382 DOI: 10.1016/j.jalz.2014.10.008  1
2015 Lindsey SE, Menon PG, Kowalski WJ, Shekhar A, Yalcin HC, Nishimura N, Schaffer CB, Butcher JT, Pekkan K. Growth and hemodynamics after early embryonic aortic arch occlusion. Biomechanics and Modeling in Mechanobiology. 14: 735-51. PMID 25416845 DOI: 10.1007/s10237-014-0633-1  1
2015 Tsai PS, Mateo C, Field JJ, Schaffer CB, Anderson ME, Kleinfeld D. Ultra-large field-of-view two-photon microscopy Optics Express. 23: 13833-13847. DOI: 10.1364/OE.23.013833  1
2014 Farrar MJ, Schaffer CB. A procedure for implanting a spinal chamber for longitudinal in vivo imaging of the mouse spinal cord. Journal of Visualized Experiments : Jove. PMID 25548864 DOI: 10.3791/52196  1
2014 Murphy PA, Kim TN, Huang L, Nielsen CM, Lawton MT, Adams RH, Schaffer CB, Wang RA. Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels. Proceedings of the National Academy of Sciences of the United States of America. 111: 18007-12. PMID 25468970 DOI: 10.1073/pnas.1415316111  1
2014 Santisakultarm TP, Paduano CQ, Stokol T, Southard TL, Nishimura N, Skoda RC, Olbricht WL, Schafer AI, Silver RT, Schaffer CB. Stalled cerebral capillary blood flow in mouse models of essential thrombocythemia and polycythemia vera revealed by in vivo two-photon imaging. Journal of Thrombosis and Haemostasis : Jth. 12: 2120-30. PMID 25263265 DOI: 10.1111/jth.12738  1
2014 Mitchell MJ, Wayne E, Rana K, Schaffer CB, King MR. TRAIL-coated leukocytes that kill cancer cells in the circulation. Proceedings of the National Academy of Sciences of the United States of America. 111: 930-5. PMID 24395803 DOI: 10.1073/pnas.1316312111  1
2014 Mitchell MJ, Wayne EC, Rana K, Schaffer CB, King MR. Unnatural killer cells: TRAIL-coated leukocytes that kill cancer cells in the circulation Proceedings of the Ieee Annual Northeast Bioengineering Conference, Nebec. 2014. DOI: 10.1109/NEBEC.2014.6972880  1
2013 Horton NG, Wang K, Kobat D, Clark CG, Wise FW, Schaffer CB, Xu C. In vivo three-photon microscopy of subcortical structures within an intact mouse brain. Nature Photonics. 7. PMID 24353743 DOI: 10.1038/nphoton.2012.336  1
2013 Shih AY, Nishimura N, Nguyen J, Friedman B, Lyden PD, Schaffer CB, Kleinfeld D. Optically induced occlusion of single blood vessels in rodent neocortex. Cold Spring Harbor Protocols. 2013: 1153-60. PMID 24298038 DOI: 10.1101/pdb.prot079509  1
2013 Devor A, Bandettini PA, Boas DA, Bower JM, Buxton RB, Cohen LB, Dale AM, Einevoll GT, Fox PT, Franceschini MA, Friston KJ, Fujimoto JG, Geyer MA, Greenberg JH, Halgren E, ... ... Schaffer CB, et al. The challenge of connecting the dots in the B.R.A.I.N. Neuron. 80: 270-4. PMID 24139032 DOI: 10.1016/j.neuron.2013.09.008  1
2013 Davis AA, Farrar MJ, Nishimura N, Jin MM, Schaffer CB. Optoporation and genetic manipulation of cells using femtosecond laser pulses. Biophysical Journal. 105: 862-71. PMID 23972838 DOI: 10.1016/j.bpj.2013.07.012  1
2013 Cianchetti FA, Kim DH, Dimiduk S, Nishimura N, Schaffer CB. Stimulus-evoked calcium transients in somatosensory cortex are temporarily inhibited by a nearby microhemorrhage. Plos One. 8: e65663. PMID 23724147 DOI: 10.1371/journal.pone.0065663  1
2013 Nishimura N, Schaffer CB. Big effects from tiny vessels: imaging the impact of microvascular clots and hemorrhages on the brain. Stroke; a Journal of Cerebral Circulation. 44: S90-2. PMID 23709743 DOI: 10.1161/STROKEAHA.112.679621  1
2013 Lauer A, Pfeilschifter W, Schaffer CB, Lo EH, Foerch C. Intracerebral haemorrhage associated with antithrombotic treatment: translational insights from experimental studies. The Lancet. Neurology. 12: 394-405. PMID 23518332 DOI: 10.1016/S1474-4422(13)70049-8  1
2013 Foerch C, Rosidi NL, Schlunk F, Lauer A, Cianchetti FA, Mandeville E, Arai K, Yigitkanli K, Fan X, Wang X, van Leyen K, Steinmetz H, Schaffer CB, Lo EH. Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice. Plos One. 8: e54203. PMID 23408937 DOI: 10.1371/journal.pone.0054203  1
2013 Chen PC, Clark C, Shen CPJ, Schaffer C, Lal A. Ultrasonically actuated inserted neural probes for increased recording reliability 2013 Transducers and Eurosensors Xxvii: the 17th International Conference On Solid-State Sensors, Actuators and Microsystems, Transducers and Eurosensors 2013. 872-875. DOI: 10.1109/Transducers.2013.6626906  1
2013 Mitchell MJ, Rana K, Wayne EC, Schaffer CB, King MR. Unnatural killer cells: TRAIL-coated leukocytes that kill cancer cells in the circulation Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 158-159.  1
2012 Kim TN, Goodwill PW, Chen Y, Conolly SM, Schaffer CB, Liepmann D, Wang RA. Line-scanning particle image velocimetry: an optical approach for quantifying a wide range of blood flow speeds in live animals. Plos One. 7: e38590. PMID 22761686 DOI: 10.1371/journal.pone.0038590  1
2012 Shih AY, Driscoll JD, Drew PJ, Nishimura N, Schaffer CB, Kleinfeld D. Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1277-309. PMID 22293983 DOI: 10.1038/jcbfm.2011.196  1
2012 Gould RA, Chin K, Santisakultarm TP, Dropkin A, Richards JM, Schaffer CB, Butcher JT. Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture. Acta Biomaterialia. 8: 1710-9. PMID 22281945 DOI: 10.1016/j.actbio.2012.01.006  1
2012 Santisakultarm TP, Cornelius NR, Nishimura N, Schafer AI, Silver RT, Doerschuk PC, Olbricht WL, Schaffer CB. In vivo two-photon excited fluorescence microscopy reveals cardiac- and respiration-dependent pulsatile blood flow in cortical blood vessels in mice. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1367-77. PMID 22268102 DOI: 10.1152/ajpheart.00417.2011  1
2012 Farrar MJ, Bernstein IM, Schlafer DH, Cleland TA, Fetcho JR, Schaffer CB. Chronic in vivo imaging in the mouse spinal cord using an implanted chamber. Nature Methods. 9: 297-302. PMID 22266542 DOI: 10.1038/nmeth.1856  1
2012 Murphy PA, Kim TN, Lu G, Bollen AW, Schaffer CB, Wang RA. Notch4 normalization reduces blood vessel size in arteriovenous malformations. Science Translational Medicine. 4: 117ra8. PMID 22261032 DOI: 10.1126/scitranslmed.3002670  1
2012 Foley CP, Nishimura N, Neeves KB, Schaffer CB, Olbricht WL. Real-time imaging of perivascular transport of nanoparticles during convection-enhanced delivery in the rat cortex. Annals of Biomedical Engineering. 40: 292-303. PMID 22009318 DOI: 10.1007/s10439-011-0440-0  1
2012 Chen PC, Clark CG, Schaffer C, Gilmour RF, Lal A. Ultrasonically enabled neural probes with co-located electrical and mechanical transduction Ieee International Ultrasonics Symposium, Ius. 350-353. DOI: 10.1109/ULTSYM.2012.0086  1
2012 Jones J, Chowdhury R, Jalloh D, Seo BK, Pandya JK, Schaffer CB, Nishimura N. In-vivo imaging of beating mouse heart with multiphoton microscopy Frontiers in Optics, Fio 2012 1
2012 Chen PC, Shen CJ, Kuo JC, Clark CG, Nijjar B, Schaffer C, Gilmour RF, Lal A. Ultrasonic neural probe for real time electromechanical histology of neural interfaces Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop. 34-37.  1
2011 Sunwoo J, Cornelius NR, Doerschuk PC, Schaffer CB. Estimating brain microvascular blood flows from partial two-photon microscopy data by computation with a circuit model. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 174-7. PMID 22254278 DOI: 10.1109/IEMBS.2011.6089922  1
2011 Huynh J, Nishimura N, Rana K, Peloquin JM, Califano JP, Montague CR, King MR, Schaffer CB, Reinhart-King CA. Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration. Science Translational Medicine. 3: 112ra122. PMID 22158860 DOI: 10.1126/scitranslmed.3002761  1
2011 Rosidi NL, Zhou J, Pattanaik S, Wang P, Jin W, Brophy M, Olbricht WL, Nishimura N, Schaffer CB. Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration. Plos One. 6: e26612. PMID 22028924 DOI: 10.1371/journal.pone.0026612  1
2011 Zhao M, Nguyen J, Ma H, Nishimura N, Schaffer CB, Schwartz TH. Preictal and ictal neurovascular and metabolic coupling surrounding a seizure focus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13292-300. PMID 21917812 DOI: 10.1523/JNEUROSCI.2597-11.2011  1
2011 Lauer A, Cianchetti FA, Van Cott EM, Schlunk F, Schulz E, Pfeilschifter W, Steinmetz H, Schaffer CB, Lo EH, Foerch C. Anticoagulation with the oral direct thrombin inhibitor dabigatran does not enlarge hematoma volume in experimental intracerebral hemorrhage. Circulation. 124: 1654-62. PMID 21911784 DOI: 10.1161/CIRCULATIONAHA.111.035972  1
2011 Nguyen J, Nishimura N, Fetcho RN, Iadecola C, Schaffer CB. Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 2243-54. PMID 21712834 DOI: 10.1038/jcbfm.2011.95  1
2011 Nguyen J, Ferdman J, Zhao M, Huland D, Saqqa S, Ma J, Nishimura N, Schwartz TH, Schaffer CB. Sub-surface, micrometer-scale incisions produced in rodent cortex using tightly-focused femtosecond laser pulses. Lasers in Surgery and Medicine. 43: 382-91. PMID 21674543 DOI: 10.1002/lsm.21054  1
2011 Santisakultarm TP, Schaffer CB. Optically quantified cerebral blood flow. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1337-8. PMID 21364601 DOI: 10.1038/jcbfm.2011.18  1
2011 Farrar MJ, Wise FW, Fetcho JR, Schaffer CB. In vivo imaging of myelin in the vertebrate central nervous system using third harmonic generation microscopy. Biophysical Journal. 100: 1362-71. PMID 21354410 DOI: 10.1016/j.bpj.2011.01.031  1
2011 Gould R, Chin K, Santisakultam P, Dropkin A, Richards J, Chiu YN, Schaffer C, Butcher J. Anisotropic strain fields enhance matrix remodeling through elevated TGF-β signaling Asme 2011 Summer Bioengineering Conference, Sbc 2011. 1215-1216. DOI: 10.1115/SBC2011-53805  1
2011 Stokol T, Esch MB, Nishimura N, Schaffer C, Daddona JL, Post DJ, Desai DP. Little channels, big disease: Using microfluidics to investigate cancer metastasis Asme 2011 9th International Conference On Nanochannels, Microchannels, and Minichannels, Icnmm 2011. 2: 655-661. DOI: 10.1115/ICNMM2011-58298  1
2010 Schaffer CB. Optical tools to produce and study small strokes in animal models. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2010: 3377-8. PMID 21097239 DOI: 10.1109/IEMBS.2010.5627919  1
2010 Nishimura N, Rosidi NL, Iadecola C, Schaffer CB. Limitations of collateral flow after occlusion of a single cortical penetrating arteriole. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1914-27. PMID 20842163 DOI: 10.1038/jcbfm.2010.157  1
2010 Yalcin HC, Shekhar A, Nishimura N, Rane AA, Schaffer CB, Butcher JT. Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1728-35. PMID 20709864 DOI: 10.1152/ajpheart.00495.2010  1
2010 Kobat D, Durst ME, Nishimura N, Wong AW, Schaffer CB, Xu C. In vivo deep tissue imaging with long wavelength multiphoton excitation Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7569. DOI: 10.1117/12.842292  1
2010 Wise FW, Renninger W, Lefrancois S, Kieu K, Farrar M, Schaffer C, Saar B, Holtom G, Xie S. Short-pulse fiber lasers for Raman microscopies Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7569. DOI: 10.1117/12.841406  1
2010 Cianchetti FA, Nishimura N, Schaffer CB. Stimulus-evoked calcium transients in somatosensory cortex are inhibited after a nearby microhemorrhage Optics Infobase Conference Papers 1
2009 Kobat D, Durst ME, Nishimura N, Wong AW, Schaffer CB, Xu C. Deep tissue multiphoton microscopy using longer wavelength excitation. Optics Express. 17: 13354-64. PMID 19654740 DOI: 10.1364/OE.17.013354  1
2009 Foley CP, Nishimura N, Neeves KB, Schaffer CB, Olbricht WL. Flexible microfluidic devices supported by biodegradable insertion scaffolds for convection-enhanced neural drug delivery. Biomedical Microdevices. 11: 915-24. PMID 19353271 DOI: 10.1007/s10544-009-9308-6  1
2008 Schaffer CB. Light and matter interactions: Going with the grain Nature Photonics. 2: 73-74. DOI: 10.1038/nphoton.2007.287  1
2008 Nguyen J, Nishimura N, Iadecola C, Schaffer CB. Femtosecond laser-driven photodisruption to induce single venule occlusions in rodent brain Optics Infobase Conference Papers 1
2008 Nishimura N, Zhou J, Iadecola C, Schaffer CB. Femtosecond laser-induced microvascular clots trigger alzheimer's disease pathology Optics Infobase Conference Papers 1
2008 Shum J, Nishimura N, Fetcho JR, Schaffer CB. Ablation of the mauthner cell lateral dendrite using femtosecond laser pulses Optics Infobase Conference Papers 1
2008 Wang P, Foley CP, Nishimura N, Schaffer C, Olbricht WL. Convection-enhanced transport of polymeric nanoparticles in the perivascular space of the brain Aiche Annual Meeting, Conference Proceedings 1
2007 Hensley C, Broaddus DH, Schaffer CB, Gaeta AL. Photonic band-gap fiber gas cell fabricated using femtosecond micromachining. Optics Express. 15: 6690-5. PMID 19546979 DOI: 10.1364/OE.15.006690  1
2007 Clay GO, Schaffer CB, Kleinfeld D. Large two-photon absorptivity of hemoglobin in the infrared range of 780-880 nm. The Journal of Chemical Physics. 126: 025102. PMID 17228976 DOI: 10.1063/1.2404678  1
2007 Nishimura N, Schaffer CB, Friedman B, Lyden PD, Kleinfeld D. Penetrating arterioles are a bottleneck in the perfusion of neocortex. Proceedings of the National Academy of Sciences of the United States of America. 104: 365-70. PMID 17190804 DOI: 10.1073/pnas.0609551104  1
2007 Hensley CJ, Broaddus DH, Schaffer CB, Gaeta AL. Variable pressure hollow-core band-gap fiber cell produced using femtosecond laser micromachining Conference On Lasers and Electro-Optics, 2007, Cleo 2007. DOI: 10.1109/CLEO.2007.4452442  1
2006 Rinia HA, Bonn M, Vartiainen EM, Schaffer CB, Müller M. Spectroscopic analysis of the oxygenation state of hemoglobin using coherent anti-Stokes Raman scattering. Journal of Biomedical Optics. 11: 050502. PMID 17092146 DOI: 10.1117/1.2355671  1
2006 Nishimura N, Schaffer CB, Friedman B, Tsai PS, Lyden PD, Kleinfeld D. Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nature Methods. 3: 99-108. PMID 16432519 DOI: 10.1038/nmeth844  1
2006 Schaffer CB, Friedman B, Nishimura N, Schroeder LF, Tsai PS, Ebner FF, Lyden PD, Kleinfeld D. Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. Plos Biology. 4: e22. PMID 16379497 DOI: 10.1371/journal.pbio.0040022  1
2006 Clay GO, Millard AC, Schaffer CB, Aus-der-Au J, Tsai PS, Squier JA, Kleinfeld D. Spectroscopy of third-harmonic generation: Evidence for resonances in model compounds and ligated hemoglobin Journal of the Optical Society of America B: Optical Physics. 23: 932-950. DOI: 10.1364/JOSAB.23.000932  1
2006 Nishimura N, Schaffer CB, Kleinfeld D. In vivo manipulation of biological systems with femtosecond laser pulses Proceedings of Spie - the International Society For Optical Engineering. 6261. DOI: 10.1117/12.668886  1
2006 Clay O, Schaffer CB, Squier JA, Kleinfeld D. Ultrafast third harmonic micro-spectroscopy reveals a two-photon resonance in human hemoglobin Proceedings of Spie - the International Society For Optical Engineering. 6108. DOI: 10.1117/12.659110  1
2006 Bovatsek J, Arai A, Schaffer CB. Three-dimensional micromachining inside transparent materials using femtosecond laser pulses: New applications Conference On Lasers and Electro-Optics and 2006 Quantum Electronics and Laser Science Conference, Cleo/Qels 2006. DOI: 10.1109/CLEO.2006.4627978  1
2006 Itoh K, Watanabe W, Nolte S, Schaffer CB. Ultrafast processes for bulk modification of transparent materials Mrs Bulletin. 31: 620-625.  1
2006 Ashcom JB, Gattass RR, Schaffer CB, Mazur E. Numerical aperture dependence of damage and supercontinuum generation from femtosecond laser pulses in bulk fused silica Journal of the Optical Society of America B: Optical Physics. 23: 2317-2322.  1
2005 Shen N, Datta D, Schaffer CB, LeDuc P, Ingber DE, Mazur E. Ablation of cytoskeletal filaments and mitochondria in live cells using a femtosecond laser nanoscissor. Mechanics & Chemistry of Biosystems : McB. 2: 17-25. PMID 16708469  1
2005 Kim TN, Campbell K, Groisman A, Kleinfeld D, Schaffer CB. Femtosecond laser-drilled capillary integrated into a microfluidic device Applied Physics Letters. 86: 1-3. DOI: 10.1063/1.1926423  1
2004 Nishimura N, Schaffer CB, Friedman B, Tsai PS, Lyden PD, Kleinfeld D. Targeted disruption of deep-lying neocortical microvessels in rat using ultrashort laser pulses Proceedings of Spie - the International Society For Optical Engineering. 5340: 179-187. DOI: 10.1117/12.555404  1
2004 Schaffer CB, Kim TN, Garcia JF, Mazur E, Groisman A, Kleinfeld D. Micromachining of bulk transparent materials using nanojoule femtosecond laser pulses Proceedings of Spie - the International Society For Optical Engineering. 5273: 469-471. DOI: 10.1117/12.525443  1
2004 Schaffer CB, Jamison AO, Mazur E. Morphology of femtosecond laser-induced structural changes in bulk transparent materials Applied Physics Letters. 84: 1441-1443. DOI: 10.1063/1.1650876  1
2004 Ifarraguerri A, Thompson B, Tsai PS, Friedman B, Schaffer CB, Lev-Ram V, Tsien RY, Squier JA, Kleinfeld D. Quantitative analysis of volumetric TPLSM data 2004 2nd Ieee International Symposium On Biomedical Imaging: Macro to Nano. 1: 804-807.  1
2003 Tsai PS, Friedman B, Ifarraguerri AI, Thompson BD, Lev-Ram V, Schaffer CB, Xiong Q, Tsien RY, Squier JA, Kleinfeld D. All-optical histology using ultrashort laser pulses. Neuron. 39: 27-41. PMID 12848930 DOI: 10.1016/S0896-6273(03)00370-2  1
2003 Schaffer CB, Tsai PS, Nishimura N, Schroeder LF, Friedman B, Lyden PD, Ebner FF, Kleinfeld D. All optical thrombotic stroke model for near-surface blood vessels in rat: Focal illumination of exogenous photosensitizers combined with real-time two-photon imaging Proceedings of Spie - the International Society For Optical Engineering. 4978: 222-231. DOI: 10.1117/12.484208  1
2003 Sundaram SK, Schaffer CB, Mazur E. Microexplosions in tellurite glasses Applied Physics a: Materials Science and Processing. 76: 379-384. DOI: 10.1007/s00339-002-1824-7  1
2003 Schaffer CB, García JF, Mazur E. Bulk heating of transparent materials using a high-repetition-rate femtosecond laser Applied Physics a: Materials Science and Processing. 76: 351-354. DOI: 10.1007/s00339-002-1819-4  1
2003 Wolfe DB, Ashcom JB, Hwang JC, Schaffer CB, Mazur E, Whitesides GM. Customization of poly(dimethylsiloxane) stamps by micromachining using a femtosecond-pulsed laser Advanced Materials. 15: 62-65. DOI: 10.1002/adma.200390012  1
2003 Schaffer CB, Ebner FF, Nishimura N, Friedman B, Tsai PS, Schroeder LF, Lyden PD, Kleinfeld D. Real-time two-photon fluorescence microscopy of blood flow dynamics following photothrombotic stroke in rat neocortex Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-Leos. 1: 307-308.  1
2003 Tsai PS, Friedman B, Ifarraguerri AI, Thompson BD, Lev-Ram V, Schaffer CB, Xiong Q, Tsien RY, Squier JA, Kleinfeld D. All optical histology: Serial ablation and multiphoton imaging of neuronal tissue with femtosecond laser pulses Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-Leos. 2: 485-486.  1
2002 Schaffer CB, Der Au JA, Mazur E, Squier JA. Micromachining and material change characterization using femtosecond laser oscillators Proceedings of Spie - the International Society For Optical Engineering. 4633: 112-118. DOI: 10.1117/12.461370  1
2002 Ashcom JB, Schaffer CB, Mazur E. Numerical aperture dependence of damage and white light generation from femtosecond laser pulses in bulk fused silica Proceedings of Spie - the International Society For Optical Engineering. 4633: 107-111. DOI: 10.1117/12.461369  1
2002 Schaffer CB, Nishimura N, Glezer EN, Kim AMT, Mazur E. Dynamics of femtosecond laser-induced breakdown in water from femtoseconds to microseconds Optics Express. 10: 196-203.  1
2001 Schaffer CB, Brodeur A, García JF, Mazur E. Micromachining bulk glass by use of femtosecond laser pulses with nanojoule energy. Optics Letters. 26: 93-5. PMID 18033517  1
2001 Fittinghoff DN, Schaffer CB, Mazur E, Squier JA. Time-decorrelated multifocal micromachining and trapping Ieee Journal On Selected Topics in Quantum Electronics. 7: 559-566. DOI: 10.1109/2944.974227  1
2001 Schaffer CB, Brodeur A, Mazur E. Laser-induced breakdown and damage in bulk transparent materials induced by tightly focused femtosecond laser pulses Measurement Science and Technology. 12: 1784-1794. DOI: 10.1088/0957-0233/12/11/305  1
2001 Schaffer CB, Jamison A, García JF, Ashcom JB, Mazur E. Morphology and mechanisms of femtosecond laser-induced structural change in bulk transparent materials Conference On Lasers and Electro-Optics Europe - Technical Digest. 445-446.  1
2001 Kim AMT, Schaffer CB, Roeser CAD, Mazur E. Two-photon-absorption FROG: Measuring white-light continuum pulses Conference On Lasers and Electro-Optics Europe - Technical Digest. 201-202.  1
2001 Shen N, Schaffer CB, Datta D, Mazur E. Photodisruption in biological tissues and single cells using femtosecond laser pulses Conference On Lasers and Electro-Optics Europe - Technical Digest. 403-404.  1
2001 Ashcom JB, Schaffer CB, Hwang JC, Mazur E, Wolfe DB, Whitesides G. Femtosecond laser-induced carbonization of polystyrene Conference On Lasers and Electro-Optics Europe - Technical Digest. 231.  1
2001 Schaffer CB, Mazur E. Micromachining using ultrashort pulses from a laser oscillator Optics and Photonics News. 12: 20-23.  1
2000 Schaffer CB, Brodeur A, Garcia JF, Leight WA, Mazur E. Micromachining optical waveguides in bulk glass using a femtosecond laser oscillator Pacific Rim Conference On Lasers and Electro-Optics, Cleo - Technical Digest. 375-376.  1
1999 Schaffer LC, Schaffer CB, Caretto J. The use of primidone in the treatment of refractory bipolar disorder. Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists. 11: 61-6. PMID 10440522 DOI: 10.1023/A:1022338330606  0.01
1999 Schaffer CB, Brodeur A, Garcia JF, Mazur E. Micromachining of bulk glass with tightly-focused femtosecond laser pulses Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-Leos. 1: 183.  1
1999 Schaffer CB, Brodeur A, Nishimura N, Mazur E. Microscopic bulk damage in dielectric materials using nanojoule femtosecond laser pulses Iqec, International Quantum Electronics Conference Proceedings. 232.  1
1998 Nishimura N, Schaffer CB, Li EH, Mazur E. Tissue ablation with 100-fs and 200-ps laser pulses Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 4: 1703-1706.  1
1997 Glezer EN, Schaffer CB, Nishimura N, Mazur E. Minimally disruptive laser-induced breakdown in water. Optics Letters. 22: 1817-9. PMID 18188376  1
1997 Glezer EN, Huang L, Finlay RJ, Her TH, Callan JP, Schaffer CB, Mazur E. Ultrafast laser-induced microexplosions in transparent materials Proceedings of Spie - the International Society For Optical Engineering. 2966: 392-403. DOI: 10.1117/12.274281  1
1996 Schaffer CB, Schaffer LC. The use of risperidone in the treatment of bipolar disorder. The Journal of Clinical Psychiatry. 57: 136. PMID 8617699  0.01
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