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Humam Kadara, Ph.D. - Publications

Affiliations: 
2008 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Cell Biology
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147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, ... ... Kadara H, et al. Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma. Nature. PMID 38499683 DOI: 10.1038/s41586-024-07277-4  0.406
2024 Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, ... ... Kadara H, et al. An atlas of epithelial cell states and plasticity in lung adenocarcinoma. Nature. PMID 38418883 DOI: 10.1038/s41586-024-07113-9  0.469
2023 Rahal Z, Kadara H. Beyond bacteria: How the intratumor mycobiome modulates lung adenocarcinoma progression. Cancer Cell. PMID 37774700 DOI: 10.1016/j.ccell.2023.09.002  0.4
2023 Dacic S, Cao X, Rabassedas NB, Sanchez-Espiridion B, Berezowska S, Han Y, Chung JH, Beasley MB, Dongmei L, Hwang D, Mino-Kenudson M, Minami Y, Papotti M, Rekhtman N, Roden AC, ... ... Kadara H, et al. Genomic staging of multifocal lung squamous cell carcinomas is independent of the comprehensive morphologic assessment. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 37717856 DOI: 10.1016/j.jtho.2023.09.275  0.387
2023 Yanagawa J, Tran LM, Salehi-Rad R, Lim RJ, Dumitras C, Fung E, Wallace WD, Prosper AE, Fishbein G, Shea C, Hong R, Kahangi B, Deng JJ, Gower AC, Liu B, ... ... Kadara H, et al. Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma. Cancer Research. PMID 37477508 DOI: 10.1158/0008-5472.CAN-23-0128  0.505
2023 Francisco-Cruz A, Rocha P, Reuben A, Krishnan SN, Das P, Chen R, Quek K, Li J, Parra ER, Solis LM, Barua S, Jiang M, Lazcano R, Chow CW, Behrens C, ... ... Kadara H, et al. Analysis of Immune Intratumor Heterogeneity Highlights Immunoregulatory and Coinhibitory Lymphocytes as Hallmarks of Recurrence in Stage I Non-Small Cell Lung Cancer. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 36: 100028. PMID 36788067 DOI: 10.1016/j.modpat.2022.100028  0.342
2022 Finnicum CT, Rahal Z, Hassane M, Treekitkarnmongkol W, Sinjab A, Morris R, Liu Y, Tang EL, Viet S, Petersen JL, Lorenzi PL, Tan L, Petrosino J, Hoffman KL, Fujimoto J, ... ... Kadara H, et al. Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes. International Journal of Molecular Sciences. 23. PMID 36142843 DOI: 10.3390/ijms231810930  0.456
2022 Hao D, Han G, Sinjab A, Gomez-Bolanos LI, Lazcano R, Serrano A, Hernandez SD, Dai E, Cao X, Hu J, Dang M, Wang R, Chu Y, Song X, Zhang J, ... ... Kadara H, et al. The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma. Cancer Discovery. PMID 36098652 DOI: 10.1158/2159-8290.CD-21-1658  0.33
2022 Irajizad E, Fahrmann JF, Long JP, Vykoukal J, Kobayashi M, Capello M, Yu CY, Cai Y, Hsiao FC, Patel N, Park S, Peng Q, Dennison JB, Kato T, Tai MC, ... ... Kadara H, et al. A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response. International Journal of Molecular Sciences. 23. PMID 36012199 DOI: 10.3390/ijms23168933  0.386
2022 Bartolacci C, Andreani C, Vale G, Berto S, Melegari M, Crouch AC, Baluya DL, Kemble G, Hodges K, Starrett J, Politi K, Starnes SL, Lorenzini D, Raso MG, Solis Soto LM, ... ... Kadara H, et al. Author Correction: Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer. Nature Communications. 13: 4640. PMID 35941179 DOI: 10.1038/s41467-022-32459-x  0.415
2022 Sinjab A, Rahal Z, Kadara H. Cell-by-Cell: Unlocking Lung Cancer Pathogenesis. Cancers. 14. PMID 35884485 DOI: 10.3390/cancers14143424  0.523
2022 Bartolacci C, Andreani C, Vale G, Berto S, Melegari M, Crouch AC, Baluya DL, Kemble G, Hodges K, Starrett J, Politi K, Starnes SL, Lorenzini D, Raso MG, Solis Soto LM, ... ... Kadara H, et al. Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer. Nature Communications. 13: 4327. PMID 35882862 DOI: 10.1038/s41467-022-31963-4  0.32
2022 Yuan B, Clowers MJ, Velasco WV, Peng S, Peng Q, Shi Y, Ramos-Castaneda M, Zarghooni M, Yang S, Babcock RL, Chang SH, Heymach JV, Zhang J, Ostrin EJ, Watowich SS, ... Kadara H, et al. Targeting IL-1β as an immune preventive and therapeutic modality for K-ras mutant lung cancer. Jci Insight. PMID 35471938 DOI: 10.1172/jci.insight.157788  0.35
2022 Hassane M, Rahal Z, Karaoghlanian N, Zhang J, Sinjab A, Wong JW, Lu W, Scheet P, Lee JJ, Raso MG, Solis LM, Fujimoto J, Chami H, Shihadeh AL, Kadara H. Chronic exposure to waterpipe smoke elicits immunomodulatory and carcinogenic effects in the lung. Cancer Prevention Research (Philadelphia, Pa.). PMID 35468191 DOI: 10.1158/1940-6207.CAPR-21-0610  0.394
2022 Tsao AS, Wistuba I, Xia D, Byers L, Diao L, Wang J, Papadimitrakopoulou V, Tang X, Lu W, Kadara H, Grigoryev DN, Selvan ME, Gümüş ZH, Tan Z, Zhang S, et al. Germline and Somatic Smoothened Mutations in Non-Small-Cell Lung Cancer Are Potentially Responsive to Hedgehog Inhibitor Vismodegib. Jco Precision Oncology. 1: 1-10. PMID 35172522 DOI: 10.1200/PO.17.00149  0.452
2021 Devarakonda S, Li Y, Martins Rodrigues F, Sankararaman S, Kadara H, Goparaju C, Lanc I, Pepin K, Waqar SN, Morgensztern D, Ward J, Masood A, Fulton R, Fulton L, Gillette MA, et al. Genomic Profiling of Lung Adenocarcinoma in Never-Smokers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2101691. PMID 34591593 DOI: 10.1200/JCO.21.01691  0.392
2021 Fakhri G, Akel R, Khalifeh I, Chami H, Hajj Ali A, Al Assaad M, Atwi H, Kadara H, Tfayli A. Prevalence of programmed death ligand-1 in patients diagnosed with non-small cell lung cancer in Lebanon. Sage Open Medicine. 9: 20503121211043709. PMID 34540227 DOI: 10.1177/20503121211043709  0.392
2021 Casarrubios M, Cruz-Bermúdez A, Nadal E, Insa A, Garcia-Campelo R, Lázaro M, Dómine M, Majem M, Rodríguez-Abreu D, Martinez-Marti A, de Castro-Carpeño J, Cobo M, López-Vivanco G, Del Barco E, Bernabé Caro R, ... ... Kadara H, et al. Pre-treatment tissue TCR repertoire evenness is associated with complete pathological response in patients with NSCLC receiving neoadjuvant chemoimmunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34376534 DOI: 10.1158/1078-0432.CCR-21-1200  0.396
2021 Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Zhang B, Della Corte CM, ... ... Kadara H, et al. Lung cancer models reveal SARS-CoV-2-induced EMT contributes to COVID-19 pathophysiology. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 34274504 DOI: 10.1016/j.jtho.2021.07.002  0.386
2021 Kadara H, Tran LM, Liu B, Vachani A, Li S, Sinjab A, Zhou XJ, Dubinett SM, Krysan K. Early Diagnosis and Screening for Lung Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 34001525 DOI: 10.1101/cshperspect.a037994  0.458
2021 Hu X, Fujimoto J, Ying L, Fukuoka J, Ashizawa K, Sun W, Reuben A, Chow CW, McGranahan N, Chen R, Hu J, Godoy MC, Tabata K, Kuroda K, Shi L, ... ... Kadara H, et al. Author Correction: Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. Nature Communications. 12: 2888. PMID 33980839 DOI: 10.1038/s41467-021-23163-3  0.304
2021 Dejima H, Hu X, Chen R, Zhang J, Fujimoto J, Parra ER, Haymaker C, Hubert SM, Duose D, Solis LM, Su D, Fukuoka J, Tabata K, Pham HHN, Mcgranahan N, ... ... Kadara H, et al. Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features. Nature Communications. 12: 2722. PMID 33976164 DOI: 10.1038/s41467-021-22890-x  0.381
2021 Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, ... ... Kadara H, et al. Resolving the spatial and cellular architecture of lung adenocarcinoma by multiregion single-cell sequencing. Cancer Discovery. PMID 33972311 DOI: 10.1158/2159-8290.CD-20-1285  0.397
2021 Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, ... ... Kadara H, et al. Single-Cell Expression Landscape of SARS-CoV-2 Receptor and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers. 13. PMID 33809063 DOI: 10.3390/cancers13061250  0.51
2021 Rocha P, Salazar R, Zhang J, Ledesma D, Solorzano JL, Mino B, Villalobos P, Dejima H, Douse DY, Diao L, Mitchell KG, Le X, Zhang J, Weissferdt A, Parra-Cuentas E, ... ... Kadara H, et al. Correction to: CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma. Cancer Immunology, Immunotherapy : Cii. PMID 33686493 DOI: 10.1007/s00262-021-02893-9  0.347
2021 Sinjab A, Daouk R, Abou-Kheir W, Kadara H. Whole Transcriptome Sequencing Analysis of Cancer Stem/Progenitor Cells Obtained from Mouse Lung Adenocarcinomas. Methods in Molecular Biology (Clifton, N.J.). 2279: 187-198. PMID 33683695 DOI: 10.1007/978-1-0716-1278-1_15  0.46
2021 Cascone T, William WN, Weissferdt A, Leung CH, Lin HY, Pataer A, Godoy MCB, Carter BW, Federico L, Reuben A, Khan MAW, Dejima H, Francisco-Cruz A, Parra ER, Solis LM, ... ... Kadara H, et al. Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial. Nature Medicine. PMID 33603241 DOI: 10.1038/s41591-020-01224-2  0.334
2021 Hu X, Estecio MR, Chen R, Reuben A, Wang L, Fujimoto J, Carrot-Zhang J, McGranahan N, Ying L, Fukuoka J, Chow CW, Pham HHN, Godoy MCB, Carter BW, Behrens C, ... ... Kadara H, et al. Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas. Nature Communications. 12: 687. PMID 33514726 DOI: 10.1038/s41467-021-20907-z  0.392
2021 Rocha P, Salazar R, Zhang J, Ledesma D, Solorzano JL, Mino B, Villalobos P, Dejima H, Douse DY, Diao L, Mitchell KG, Le X, Zhang J, Weissferdt A, Parra-Cuentas E, ... ... Kadara H, et al. CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma. Cancer Immunology, Immunotherapy : Cii. PMID 33416944 DOI: 10.1007/s00262-020-02820-4  0.309
2020 Le X, Negrao MV, Reuben A, Federico L, Diao L, McGrail D, Nilsson M, Robichaux J, Munoz IG, Patel S, Elamin Y, Fan YH, Lee WC, Parra E, Solis Soto LM, ... ... Kadara H, et al. Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 33388477 DOI: 10.1016/j.jtho.2020.12.010  0.33
2020 Gaudreau PO, Negrao MV, Mitchell KG, Reuben A, Corsini EM, Li J, Karpinets T, Wang Q, Diao L, Wang J, Federico L, Parra-Cuentas ER, Khairullah R, Behrens C, Correa AM, ... ... Kadara H, et al. Neoadjuvant Chemotherapy Increases Cytotoxic T cell, Tissue Resident Memory T cell and B Cell Infiltration in Resectable Non-Small Cell Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 33096269 DOI: 10.1016/j.jtho.2020.09.027  0.441
2020 Daouk R, Bahmad HF, Saleh E, Monzer A, Ballout F, Kadara H, Abou-Kheir W. Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets. Plos One. 15: e0237442. PMID 32790767 DOI: 10.1371/Journal.Pone.0237442  0.395
2020 Behrens C, Rocha P, Parra ER, Feng L, Rodriguez-Canales J, Solis LM, Mino B, Zhang J, Gibbons DL, Sepesi B, Rice D, Heymach JV, Moran C, Creighton CJ, Lee JJ, ... Kadara H, et al. Female Gender Predicts Augmented Immune Infiltration in Lung Adenocarcinoma. Clinical Lung Cancer. PMID 32763065 DOI: 10.1016/J.Cllc.2020.06.003  0.418
2020 Treekitkarnmongkol W, Hassane M, Sinjab A, Chang K, Hara K, Rahal Z, Zhang J, Lu W, Sivakumar S, McDowell TL, Kantrowitz J, Zhou J, Lang W, Xu L, Ochieng JK, ... ... Kadara H, et al. Augmented Lipocalin-2 is Associated with COPD and Counteracts Lung Adenocarcinoma Development. American Journal of Respiratory and Critical Care Medicine. PMID 32730093 DOI: 10.1164/Rccm.202004-1079Oc  0.565
2020 Habli Z, AlChamaa W, Saab R, Kadara H, Khraiche ML. Circulating Tumor Cell Detection Technologies and Clinical Utility: Challenges and Opportunities. Cancers. 12. PMID 32708837 DOI: 10.3390/Cancers12071930  0.374
2020 Deng S, Ramos-Castaneda M, Velasco WV, Clowers MJ, Gutierrez BA, Noble O, Dong Y, Zarghooni M, Alvarado L, Caetano MS, Yang S, Ostrin EJ, Behrens C, Wistuba II, Stabile LP, ... Kadara H, et al. Interplay between Estrogen and Stat3/NF-κB Driven Immunomodulation in Lung Cancer. Carcinogenesis. PMID 32603404 DOI: 10.1093/Carcin/Bgaa064  0.415
2020 Stewart CA, Gay CM, Ramkumar K, Cargill KR, Cardnell RJ, Nilsson MB, Heeke S, Park EM, Kundu ST, Diao L, Wang Q, Shen L, Xi Y, Maria Della Corte C, Fan Y, ... ... Kadara H, et al. SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models. Biorxiv : the Preprint Server For Biology. PMID 32577652 DOI: 10.1101/2020.05.28.122291  0.352
2020 Al Matari N, Deeb G, Mshiek H, Sinjab A, Kadara H, Abou-Kheir W, Mhanna R. Anti-Tumor Effects of Biomimetic Sulfated Glycosaminoglycans on Lung Adenocarcinoma Cells in 2D and 3D In Vitro Models. Molecules (Basel, Switzerland). 25. PMID 32503108 DOI: 10.3390/Molecules25112595  0.482
2020 Mitchell KG, Amini B, Wang Y, Carter BW, Godoy MCB, Parra ER, Behrens C, Villalobos P, Reuben A, Lee JJ, Weissferdt A, Moran CA, Fujimoto J, Sepesi B, Walsh GL, ... ... Kadara H, et al. F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer. Cancer Immunology, Immunotherapy : Cii. PMID 32300858 DOI: 10.1007/S00262-020-02560-5  0.402
2020 Saab S, Zalzale H, Rahal Z, Khalifeh Y, Sinjab A, Kadara H. Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment. Frontiers in Immunology. 11: 159. PMID 32117295 DOI: 10.3389/Fimmu.2020.00159  0.567
2020 Reuben A, Zhang J, Chiou SH, Gittelman RM, Li J, Lee WC, Fujimoto J, Behrens C, Liu X, Wang F, Quek K, Wang C, Kheradmand F, Chen R, Chow CW, ... ... Kadara H, et al. Comprehensive T cell repertoire characterization of non-small cell lung cancer. Nature Communications. 11: 603. PMID 32001676 DOI: 10.1038/S41467-019-14273-0  0.509
2020 Treekitkarnmongkol W, Finnicum C, Sinjab A, Hassane M, Davis C, Davies GE, Hoffman KL, Fujimoto J, McAllister F, Sepesi B, Cascone T, Jenq RR, Petrosino J, Ehli E, Moghaddam SJ, ... Kadara H, et al. Abstract 3349: Evolution of the gut Amicrobiome during the pathogenesis of smoking-associated Kras-mutant lung cancer Immunology. 80: 3349-3349. DOI: 10.1158/1538-7445.Am2020-3349  0.478
2020 Sinjab A, Han G, Treekitkarnmongkol W, Brennan P, Hara K, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Zhang J, Sepesi B, Cascone T, Gibbons DL, Chen J, Eapen G, ... ... Kadara H, et al. Abstract 1518: A single-cell transcriptomic atlas of lung adenocarcinoma and adjacent normal-appearing tissue Tumor Biology. DOI: 10.1158/1538-7445.Am2020-1518  0.513
2019 Jakubek YA, Chang K, Sivakumar S, Yu Y, Giordano MR, Fowler J, Huff CD, Kadara H, Vilar E, Scheet P. Large-scale analysis of acquired chromosomal alterations in non-tumor samples from patients with cancer. Nature Biotechnology. PMID 31685958 DOI: 10.1038/S41587-019-0297-6  0.406
2019 Shi B, Behrens C, Vaghani V, Riquelme EM, Rodriguez-Canales J, Kadara H, Lin H, Lee J, Liu H, Wistuba I, Simon G. Oncogenic enhancer of zeste homolog 2 is an actionable target in patients with non-small cell lung cancer. Cancer Medicine. PMID 31456359 DOI: 10.1002/Cam4.1855  0.546
2019 Khoueiry P, Fakhri G, Akel R, El Assaad M, Mahfouz R, Khuri F, Chami H, Petersen J, Viet S, Davies G, Kadara H, Tfayli A. Deep targeted sequencing analysis of hot spot mutations in non-small cell lung cancer patients from the Middle Eastern population. Journal of Thoracic Disease. 11: 2383-2391. PMID 31372275 DOI: 10.21037/Jtd.2019.05.74  0.526
2019 Kudo Y, Haymaker C, Zhang J, Reuben A, Duose DY, Fujimoto J, Roy-Chowdhuri S, Solis Soto LM, Dejima H, Parra-Cuentas ER, Mino B, Abraham R, Ikeda N, Vaporcyan A, Gibbons D, ... ... Kadara H, et al. Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 31282941 DOI: 10.1093/Annonc/Mdz207  0.537
2019 Hu X, Fujimoto J, Ying L, Fukuoka J, Ashizawa K, Sun W, Reuben A, Chow CW, McGranahan N, Chen R, Hu J, Godoy MC, Tabata K, Kuroda K, Shi L, ... ... Kadara H, et al. Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. Nature Communications. 10: 2978. PMID 31278276 DOI: 10.1038/S41467-019-10877-8  0.512
2019 Daouk R, Hassane M, Bahmad HF, Sinjab A, Fujimoto J, Abou-Kheir W, Kadara H. Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From -Deficient Murine Lung Adenocarcinoma With Somatic Mutations. Frontiers in Oncology. 9: 207. PMID 31001473 DOI: 10.3389/Fonc.2019.00207  0.51
2019 Sivakumar S, San Lucas FA, Jakubek YA, McDowell TL, Lang W, Kallsen N, Peyton S, Davies GE, Fukuoka J, Yatabe Y, Zhang J, Futreal PA, Fowler J, Fujimoto J, Ehli EA, ... ... Kadara H, et al. Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung. Ebiomedicine. PMID 30905849 DOI: 10.1016/J.Ebiom.2019.03.020  0.535
2019 Kadara H, Sivakumar S, Jakubek Y, San Lucas FA, Lang W, McDowell T, Weber Z, Behrens C, Davies GE, Kalhor N, Moran C, El-Zein R, Mehran R, Swisher SG, Wang J, et al. Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer. American Journal of Respiratory and Critical Care Medicine. PMID 30896962 DOI: 10.1164/Rccm.201806-1178Oc  0.541
2019 Nehme E, Rahal Z, Sinjab A, Khalil A, Chami H, Nemer G, Kadara H. Epigenetic Suppression of the T-box Subfamily 2 () in Human Non-Small Cell Lung Cancer. International Journal of Molecular Sciences. 20. PMID 30866410 DOI: 10.3390/Ijms20051159  0.554
2019 Hassane M, Treekitkarnmongkol W, McDowell TL, Sivakumar S, Lang W, Ochieng JK, Nunomura-Nakamura S, Finnicum C, Davis C, Davies GE, Fukuoka J, Cascone T, McAllister F, Wistuba II, Ehli E, ... ... Kadara H, et al. Abstract 4952: Host lipocalin 2 protects againstKrasmutant lung cancer development by maintaining an anti-tumor immune contexture Cancer Research. 79: 4952-4952. DOI: 10.1158/1538-7445.Am2019-4952  0.537
2019 Kudo Y, Haymaker C, Zhang J, Reuben A, Duose DY, Fujimoto J, Roy-Chowdhuri S, Solis LM, Dejima H, Cuentas ER, Mino B, Abraham R, Ikeda N, Luthra R, Lee JJ, ... Kadara H, et al. Abstract 2790: Characterization of the immune microenvironment in brain metastasis from non-small cell lung cancer Cancer Research. 79: 2790-2790. DOI: 10.1158/1538-7445.Am2019-2790  0.484
2019 Rocha P, Salazar R, Solorzano J, Zhang J, Mino B, Parra E, Ledesma D, Kadara H, Zhang J, Vaporciyan A, Rice D, Kalhor N, Moran C, Gibbons D, Weissferdt A, et al. P1.04-79 CD73 Expression in Lung Adenocarcinomas and Immunological and Molecular Associations Journal of Thoracic Oncology. 14: S473. DOI: 10.1016/J.Jtho.2019.08.982  0.446
2019 Kudo Y, Haymaker C, Zhang J, Reuben A, Duose D, Fujimoto J, Roy-Chowdhuri S, Solis L, Dejima H, Cuentas EP, Mino B, Ikeda N, Luthra R, Gibbons D, Zhang J, ... ... Kadara H, et al. P1.04-07 Immune Suppressive Microenvironment and Highly Clonal Concordance of TCR Repertoire in Brain Metastases from Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 14: S441. DOI: 10.1016/J.Jtho.2019.08.910  0.519
2019 Reuben A, Zhang J, Gittelman R, Chiou S, Li J, Fujimoto J, Behrens C, Kheradmand F, Chow C, Bernatchez C, Eterovic A, Benzeno S, Vignali M, Wu XX, Ye Y, ... ... Kadara H, et al. MA11.09 Increased Frequency of Bystander T Cells in the Lungs Is Associated with Recurrence in Localized Non-Small Cell Lung Cancer Journal of Thoracic Oncology. 14: S293. DOI: 10.1016/J.Jtho.2019.08.589  0.549
2018 Khalil A, Dekmak B, Boulos F, Kantrowitz J, Spira A, Fujimoto J, Kadara H, El-Hachem N, Nemer G. Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the Subfamily of Tumor Suppressor Genes. Frontiers in Oncology. 8: 482. PMID 30425966 DOI: 10.3389/Fonc.2018.00482  0.589
2018 Caetano MS, Hassane M, Van HT, Bugarin E, Cumpian AM, McDowell CL, Cavazos CG, Zhang H, Deng S, Diao L, Wang J, Evans SE, Behrens C, Wistuba II, Fuqua SAW, ... ... Kadara H, et al. Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer. Nature Communications. 9: 4589. PMID 30389925 DOI: 10.1038/S41467-018-07042-Y  0.433
2018 Bauer AK, Umer M, Richardson VL, Cumpian AM, Harder AQ, Khosravi N, Azzegagh Z, Hara NM, Ehre C, Mohebnasab M, Caetano MS, Merrick DT, van Bokhoven A, Wistuba II, Kadara H, et al. Requirement for MUC5AC in KRAS-dependent lung carcinogenesis. Jci Insight. 3. PMID 30089720 DOI: 10.1172/Jci.Insight.120941  0.616
2018 Khosravi N, Caetano MS, Cumpian AM, Unver N, De la Garza Ramos C, Noble O, Daliri S, Hernandez BJ, Gutierrez BA, Evans SE, Hanash S, Alekseev AM, Yang Y, Chang SH, Nurieva R, ... Kadara H, et al. IL22 Promotes Kras Mutant Lung Cancer by Induction of a Pro-Tumor Immune Response and Protection of Stemness Properties. Cancer Immunology Research. PMID 29764837 DOI: 10.1158/2326-6066.Cir-17-0655  0.505
2018 Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, et al. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: 1072. PMID 29688333 DOI: 10.1093/Annonc/Mdx062  0.436
2018 Kantrowitz J, Sinjab A, Xu L, McDowell TL, Sivakumar S, Lang W, Nunomura-Nakamura S, Fukuoka J, Nemer G, Darwiche N, Chami H, Tfayli A, Wistuba II, Scheet P, Fujimoto J, ... ... Kadara H, et al. Genome-wide gene expression changes in the normal-appearing airway during the evolution of smoking-associated lung adenocarcinoma. Cancer Prevention Research (Philadelphia, Pa.). PMID 29382653 DOI: 10.1158/1940-6207.Capr-17-0295  0.555
2018 Hu X, Fujimoto J, Chen R, Chow C, Sun W, Song X, Mao X, Scheet P, Kadara H, Behrens C, Wu C, Lee JJ, Antonoff M, Vaporciyan AA, Swisher S, et al. Genomic evolutions in the progression from lung preneoplasia to adenocarcinoma. Journal of Clinical Oncology. 36: 8576-8576. DOI: 10.1200/Jco.2018.36.15_Suppl.8576  0.419
2018 Khalil A, El-Hachem N, Dekmak B, Kadara H, Nemer G. Abstract 5513: Role of the evolutionarily conserved TBX2 subfamily of transcription factors in the molecular pathogenesis of human lung adenocarcinoma Cancer Research. 78: 5513-5513. DOI: 10.1158/1538-7445.Am2018-5513  0.598
2018 Chen R, Fujimoto J, Reuben A, Ying L, Hu X, Chow C, Canales JR, Sun W, Hu J, Cuentas ERP, Behrens C, Wu C, Little L, Gumbs C, Wiesnoski D, ... ... Kadara H, et al. Abstract 4686: T cell repertoire evolution from the normal lung to invasive lung adenocarcinoma Immunology. 78: 4686-4686. DOI: 10.1158/1538-7445.Am2018-4686  0.551
2018 Sivakumar S, Jakubek Y, Lucas FAS, Lang W, McDowell C, Weber Z, Behrens C, Kalhor N, Moran C, El-Zein R, Davies G, Fujimoto J, Mehran R, Swisher SG, Wang J, ... ... Kadara H, et al. Abstract 3997: Somatic mutational processes in the cancerization field of the normal-appearing airway reveal early drivers in the development of non-small cell lung cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-3997  0.534
2017 Khalil AA, Sivakumar S, Lucas FAS, McDowell T, Lang W, Tabata K, Fujimoto J, Yatabe Y, Spira A, Scheet P, Nemer G, Kadara H. TBX2 subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection. Oncotarget. 8: 68230-68241. PMID 28978111 DOI: 10.18632/Oncotarget.19938  0.595
2017 Sivakumar S, San Lucas FA, McDowell TL, Lang W, Xu L, Fujimoto J, Zhang J, Futreal PA, Fukuoka J, Yatabe Y, Dubinett SM, Spira AE, Fowler J, Hawk ET, Wistuba II, ... ... Kadara H, et al. Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma. Cancer Research. PMID 28951454 DOI: 10.1158/0008-5472.Can-17-1605  0.528
2017 Rahal Z, El Nemr S, Sinjab A, Chami H, Tfayli A, Kadara H. Smoking and Lung Cancer: A Geo-Regional Perspective. Frontiers in Oncology. 7: 194. PMID 28920053 DOI: 10.3389/fonc.2017.00194  0.391
2017 Fujimoto J, Nunomura-Nakamura S, Liu Y, Lang W, McDowell T, Jakubek Y, Ezzeddine D, Ochieng JK, Petersen J, Davies G, Fukuoka J, Wistuba II, Ehli E, Fowler J, Scheet P, ... Kadara H, et al. Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a. International Journal of Cancer. PMID 28653505 DOI: 10.1002/Ijc.30851  0.537
2017 Cascone T, Xu L, Lin HY, Liu W, Tran HT, Liu Y, Howells KJ, Haddad V, Hanrahan EO, Nilsson M, Cortez MA, Giri U, Kadara H, Saigal B, Park YY, et al. The HGF/c-MET pathway is a driver and biomarker of VEGFR-inhibitor resistance and vascular remodeling in non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28559461 DOI: 10.1158/1078-0432.Ccr-16-3216  0.491
2017 Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, et al. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 28368511 DOI: 10.1093/annonc/mdx062  0.33
2017 Choi M, Kadara H, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Kim K, Kalhor N, Moran C, Rimm D, Swisher S, et al. Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 28: 83-89. PMID 28177435 DOI: 10.1093/Annonc/Mdw437  0.471
2017 Kadara H, Nemer G, Safi R, Rebeiz N, Daou L, Delbani D, Btadini W, Abbas O, Tofaili M, Bitar F, Kibbi AG, Shimomura Y, Kurban M. Erythropoietic Protoporphyria (EPP), a Clinical and Molecular Study from Lebanon: Ferrochelatase a Potential Tumor Suppressor Gene in Colon Cancer. Clinical Genetics. PMID 28075030 DOI: 10.1111/Cge.12968  0.41
2017 Seth S, Lee W, Zhang J, Fujimoto J, Behrens C, McDowell C, Kalhor N, Weissferdt A, Papadimitrakopoulou V, Heymach J, Gibbons DL, Futreal A, Wistuba II, Amit M, Kadara H, et al. Genomic and transcriptomic profiling of localized sarcomatoid carcinoma of the lung to reveal association between immune activation and a lower risk of recurrence. Journal of Clinical Oncology. 35: e20058-e20058. DOI: 10.1200/Jco.2017.35.15_Suppl.E20058  0.518
2017 Tsao AS, Wistuba II, Xia D, Byers LA, Diao L, Wang J, Papadimitrakopoulou V, Tang X, Lu W, Kadara H, Gumus ZH, Tan Z, Zhang S, Nilsson MB, Heymach J. Response of germline and somatic smoothened (SMO) mutations in non-small cell lung cancer (NSCLC) to hedgehog inhibitor vismodegib. Journal of Clinical Oncology. 35: 9062-9062. DOI: 10.1200/Jco.2017.35.15_Suppl.9062  0.516
2017 Caetano MS, Van H, Bugarin E, Cumpian A, McDowell CL, Zhang H, Evans SE, Watowich S, Kadara H, Moghaddam SJ. Abstract 3974: Gender specific function of epithelial IL-6-STAT3 pathway in K-ras mutant lung cancer Cancer Research. 77: 3974-3974. DOI: 10.1158/1538-7445.Am2017-3974  0.562
2017 Umer M, Cumpian AM, Khosravi N, Azzegagh Z, Mohebnasab M, Caetano MS, Ostrin EJ, Wistuba II, Dickey B, Kadara H, Evans CM, Moghaddam SJ. Abstract 3714: Muc5ac plays an essential role in promotion of k-ras mutant lung cancer Immunology. 77: 3714-3714. DOI: 10.1158/1538-7445.Am2017-3714  0.441
2017 Jakubek YA, Sivakumar S, Strong LC, Kadara H, Scheet P. Abstract 3587: Intratumoral divergence of copy number alterations in NSCLC Cancer Research. 77: 3587-3587. DOI: 10.1158/1538-7445.Am2017-3587  0.391
2017 Sivakumar S, Jakubek Y, Lang W, McDowell T, Garcia MM, Chow C, Weber Z, Behrens C, Kalhor N, Moran C, El-Zein R, Davies G, Fujimoto J, Mehran R, Swisher SG, ... ... Kadara H, et al. Abstract 1434: Mutational landscape in the normal-appearing airway cancerization field of early-stage non-small cell lung cancer Cancer Research. 77: 1434-1434. DOI: 10.1158/1538-7445.Am2017-1434  0.533
2017 Sivakumar S, San Lucas F, McDowell T, Lang W, Xu L, Fujimoto J, Zhang J, Wistuba I, Futreal F, Fukuoka J, Yatabe Y, Dubinett S, Spira A, Fowler J, Hawk E, ... ... Kadara H, et al. Genomic Landscape of Atypical Adenomatous Hyperplasia and Their Progression to Lung Adenocarcinomas Journal of Thoracic Oncology. 12: S1546. DOI: 10.1016/J.Jtho.2017.06.061  0.49
2017 Skoulidis F, Elamin Y, Papadimitrakopoulou V, Tong P, Wang J, Lewis J, Rinsurongkawong W, Chu C, Roarty E, Zhang J, Tran H, Rodriguez-Canales J, Parra E, Behrens C, Kadara H, et al. MA04.07 Impact of Major Co-Mutations on the Immune Contexture and Response of KRAS-Mutant Lung Adenocarcinoma to Immunotherapy Journal of Thoracic Oncology. 12: S361-S362. DOI: 10.1016/J.Jtho.2016.11.402  0.451
2016 Kadara H, Choi M, Zhang J, Cuentas EP, Canales JR, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, et al. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 27687306 DOI: 10.1093/Annonc/Mdw436  0.493
2016 Choi M, Kadara H, Zhang J, Cuentas EP, Canales JR, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Kim K, Kalhor N, Moran C, Rimm D, Swisher S, et al. Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 27687303 DOI: 10.1093/annonc/mdw437  0.463
2016 Parra ER, Behrens C, Rodriguez-Canales J, Lin HY, Mino B, Blando J, Zhang J, Gibbons DL, Heymach JV, Sepesi B, Swisher SG, Weissferdt A, Kalhor N, Izzo J, Kadara H, et al. Image Analysis-Based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non-Small Cell Lung Carcinoma Patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27252415 DOI: 10.1158/1078-0432.Ccr-15-2443  0.479
2016 Jakubek Y, Lang W, Vattathil S, Garcia M, Xu L, Huang L, Yoo SY, Shen L, Lu W, Chow CW, Weber Z, Davies G, Huang J, Behrens C, Kalhor N, ... ... Kadara H, et al. Genomic landscape established by allelic imbalance in the cancerization field of a normal appearing airway. Cancer Research. PMID 27216194 DOI: 10.1158/0008-5472.Can-15-3064  0.561
2016 Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, et al. IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer. Cancer Research. PMID 27197187 DOI: 10.1158/0008-5472.Can-15-2840  0.516
2016 Kadara H, Scheet P, Wistuba II, Spira AE. Early events in the molecular pathogenesis of lung cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 27006378 DOI: 10.1158/1940-6207.Capr-15-0400  0.565
2016 Kadara H, Choi M, Zhang J, Cuentas EP, Canales JR, Gaffney S, Zhao Z, Behrens C, Fujimoto J, Chow C, Kalhor N, Moran C, Rimm D, Swisher SG, Gibbons DL, et al. Abstract 89: Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma Cancer Research. 76: 89-89. DOI: 10.1158/1538-7445.Am2016-89  0.46
2016 Parra ER, Tong P, Kadara H, Papadimitrakopoulou V, Izzo J, Rodriguez-Canales J, Behrens C, Minna JD, Wang J, Wistuba II, Heymach JV, Skoulidis F. Abstract 532: Impact of APOBEC mutagenesis on the immune microenvironment of lung adenocarcinoma (LUAC) Cancer Research. 76: 532-532. DOI: 10.1158/1538-7445.Am2016-532  0.482
2016 Fujimoto J, Nunomura S, Lang W, Liu Y, Wei J, Ochieng J, Jakubek Y, Ostrin E, Petersen J, Davies G, Darwiche N, Ehli E, Fowler J, Scheet P, Kadara H. Abstract 4056: Development of Kras mutant lung adenocarcinoma in tobacco carcinogen exposed mice with knockout of the airway lineage-specific G-protein coupled receptor Gprc5a Cancer Research. 76: 4056-4056. DOI: 10.1158/1538-7445.Am2016-4056  0.595
2016 Choi M, Kadara H, Zhang J, Cuentas EP, Canales JR, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, et al. Abstract 142: Mutation and immune profiles in early-stage lung squamous cell carcinoma Cancer Research. 76: 142-142. DOI: 10.1158/1538-7445.Am2016-142  0.493
2016 Ochieng J, Nunomura S, Lang W, Wei J, Xu L, McDowell C, Ostrin E, Arlinghaus R, Fujimoto J, Kadara H. Abstract 1124: Expression of the lipocalin 2 oncogene in the development of smoking-associated and Kras mutant lung adenocarcinoma Cancer Research. 76: 1124-1124. DOI: 10.1158/1538-7445.Am2016-1124  0.568
2016 Skoulidis F, Denning W, Diao L, Tong P, Fan YH, Papadimitrakopoulou V, Izzo J, Behrens C, Kadara H, Parra Cuentas ER, Canales JR, Wang J, Byers LA, Wistuba II, Heymach JV. Impact of co-mutations on the immune microenvironment of KRAS-mutant lung adenocarcinoma Journal of Thoracic Oncology. 11: S13-S14. DOI: 10.1016/J.Jtho.2015.12.021  0.461
2015 Peng S, Sen B, Mazumdar T, Byers LA, Diao L, Wang J, Tong P, Giri U, Heymach JV, Kadara HN, Johnson FM. Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations. Oncotarget. PMID 26623721 DOI: 10.18632/Oncotarget.6376  0.362
2015 Maki Y, Fujimoto J, Lang W, Xu L, Behrens C, Wistuba II, Kadara H. LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells. Scientific Reports. 5: 13846. PMID 26343532 DOI: 10.1038/Srep13846  0.606
2015 Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Rodriguez Canales J, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, et al. Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities. Cancer Discovery. PMID 26069186 DOI: 10.1158/2159-8290.Cd-14-1236  0.558
2015 Skoulidis F, Denning W, Diao L, Tong P, Fan YH, Papadimitrakopoulou V, Izzo J, Behrens C, Kadara H, Parra Cuentas ER, Rodriguez J, Wang J, Gibbons DL, Byers LA, Wistuba II, et al. Association of inactivation of STK11/ LKB1 with a suppressive immune microenvironment in lung adenocarcinoma (LUAC). Journal of Clinical Oncology. 33: 11002-11002. DOI: 10.1200/Jco.2015.33.15_Suppl.11002  0.401
2015 Johnson F, Sen B, Mazumdar T, Peng S, Kadara H, Diao L, Byers L. Abstract IA10: Kinase-impaired BRAF mutations as predictors of resistance and sensitivity Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-Ia10  0.449
2015 Skoulidis F, Byers L, Diao L, Papadimitrakopoulou V, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Rodriguez-Canales J, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, et al. Abstract 968: Co-occurring genomic alterations define major subsets ofKRAS-mutant lung adenocarcinoma (LUAC) with distinct biology and therapeutic vulnerabilities Cancer Research. 75: 968-968. DOI: 10.1158/1538-7445.Am2015-968  0.461
2015 Parra ER, Behrens C, Rodriguez-Canales J, Lin H, Mino B, Blando J, Lou Y, Gibbons DL, Heymach JV, Swisher SG, Weissferdt A, Kahlor N, Izzo J, Lee JJ, Kadara H, et al. Abstract 4256: High programmed cell death ligand 1 expression and low immune infiltrate score correlate with worse outcome in patients with lung adenocarcinoma Cancer Research. 75: 4256-4256. DOI: 10.1158/1538-7445.Am2015-4256  0.472
2015 Jakubek Y, Lang W, Vattathil S, Garcia M, Huang L, Lu W, Chow C, Weber Z, Davies GE, Behrens C, Kalhor N, Moran C, Fujimoto J, Mehran RJ, Fowler J, ... ... Kadara H, et al. Abstract 2993: The landscape of DNA allelic imbalance in the normal-appearing airway field of cancerization Cancer Research. 75: 2993-2993. DOI: 10.1158/1538-7445.Am2015-2993  0.322
2014 Kadara H, Fujimoto J, Yoo SY, Maki Y, Gower AC, Kabbout M, Garcia MM, Chow CW, Chu Z, Mendoza G, Shen L, Kalhor N, Hong WK, Moran C, Wang J, et al. Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer. Journal of the National Cancer Institute. 106: dju004. PMID 24563515 DOI: 10.1093/Jnci/Dju004  0.505
2014 Gold KA, Kim ES, Liu DD, Yuan P, Behrens C, Solis LM, Kadara H, Rice DC, Wistuba II, Swisher SG, Hofstetter WL, Lee JJ, Hong WK. Prediction of survival in resected non-small cell lung cancer using a protein expression-based risk model: implications for personalized chemoprevention and therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1946-54. PMID 24366692 DOI: 10.1158/1078-0432.Ccr-13-1959  0.475
2014 Sen B, Peng S, Mazumdar T, Byers LA, Kadara H, Johnson FM. Abstract 3707: The multitargeted kinase inhibitor dasatinib induces DNA damage, Hippo pathway engagement and senescence in lung cancer cell lines that possess kinase-inactivating BRAF mutations Cancer Research. 74: 3707-3707. DOI: 10.1158/1538-7445.Am2014-3707  0.521
2014 Kusko R, Garrison C, Wang T, Campbell J, Perez-Rogers J, Luo L, Beane J, Liu G, Kadara H, Belinsky S, Lenburg ME, Spira A. Abstract 3554: Gene and miRNA expression networks specific to never smoker lung adenocarcinoma Cancer Research. 74: 3554-3554. DOI: 10.1158/1538-7445.Am2014-3554  0.487
2014 Kusko R, Anderlind C, Wang G, Zhang S, Wallace WD, Wasler T, Ebright M, Garcia MM, Eisenberg R, Lee G, Liu G, Elashoff D, Kalhor N, Moran C, Mehran R, ... ... Kadara H, et al. Abstract 2352: Mapping the airway-wide molecular field of injury in smokers with lung cancer Cancer Research. 74: 2352-2352. DOI: 10.1158/1538-7445.Am2014-2352  0.584
2014 Maki Y, Fujimoto J, Yoo S, Garcia M, Gower A, Shen L, Chow C, Behrens C, Kalhor N, Moran C, Wang J, Spira A, Coombes KR, Wistuba II, Kadara H. Abstract 1597: Transcriptomic architecture of the field of cancerization in the adjacent normal-appearing airway: Early mechanisms in lung carcinogenesis Cancer Research. 74: 1597-1597. DOI: 10.1158/1538-7445.Am2014-1597  0.621
2013 Behrens C, Solis LM, Lin H, Yuan P, Tang X, Kadara H, Riquelme E, Galindo H, Moran CA, Kalhor N, Swisher SG, Simon GR, Stewart DJ, Lee JJ, Wistuba II. EZH2 protein expression associates with the early pathogenesis, tumor progression, and prognosis of non-small cell lung carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6556-65. PMID 24097870 DOI: 10.1158/1078-0432.Ccr-12-3946  0.548
2013 Kabbout M, Garcia MM, Fujimoto J, Liu DD, Woods D, Chow CW, Mendoza G, Momin AA, James BP, Solis L, Behrens C, Lee JJ, Wistuba II, Kadara H. ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3383-95. PMID 23659968 DOI: 10.1158/1078-0432.Ccr-13-0341  0.615
2013 Kadara H, Shen L, Fujimoto J, Saintigny P, Chow CW, Lang W, Chu Z, Garcia M, Kabbout M, Fan YH, Behrens C, Liu DA, Mao L, Lee JJ, Gold KA, et al. Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling. Cancer Prevention Research (Philadelphia, Pa.). 6: 8-17. PMID 23087048 DOI: 10.1158/1940-6207.Capr-12-0290  0.512
2013 Maki Y, Fujimoto J, Yoo S, Gower A, Shen L, Garcia MM, Kabbout M, Chow C, Hong WK, Kalhor N, Wang J, Moran C, Spira A, Coombes KR, Wistuba II, ... Kadara H, et al. Abstract 2367: Transcriptomic architecture of the airway field cancerization in early-stage non-small cell lung cancer . Cancer Research. 73: 2367-2367. DOI: 10.1158/1538-7445.Am2013-2367  0.63
2012 Fujimoto J, Kadara H, Garcia MM, Kabbout M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, Moran C, Sharafkhaneh A, Lotan R, Wistuba II. G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 1747-54. PMID 23154545 DOI: 10.1097/Jto.0B013E31826Bb1Ff  0.692
2012 Nunez MI, Behrens C, Woods DM, Lin H, Suraokar M, Kadara H, Hofstetter W, Kalhor N, Lee JJ, Franklin W, Stewart DJ, Wistuba II. High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 833-40. PMID 22729036 DOI: 10.1097/Jto.0B013E31824De09C  0.518
2012 Kadara H, Wistuba II. Field cancerization in non-small cell lung cancer: implications in disease pathogenesis. Proceedings of the American Thoracic Society. 9: 38-42. PMID 22550239 DOI: 10.1513/pats.201201-004MS  0.483
2012 Kadara H, Kabbout M, Wistuba II. Pulmonary adenocarcinoma: a renewed entity in 2011. Respirology (Carlton, Vic.). 17: 50-65. PMID 22040022 DOI: 10.1111/J.1440-1843.2011.02095.X  0.589
2012 Solis LM, Behrens C, Raso MG, Lin HY, Kadara H, Yuan P, Galindo H, Tang X, Lee JJ, Kalhor N, Wistuba II, Moran CA. Histologic patterns and molecular characteristics of lung adenocarcinoma associated with clinical outcome. Cancer. 118: 2889-99. PMID 22020674 DOI: 10.1002/Cncr.26584  0.451
2012 Behrens C, Solis L, Lin H, Tang X, Yuan P, Kadara H, Riquelme E, Galindp H, Hong WK, Lee JJ, Wistuba II. Abstract 3685: Analysis of EZH2 and TTF-1 protein expression identifies a subset of lung adenocarcinomas with better prognosis Cancer Research. 72: 3685-3685. DOI: 10.1158/1538-7445.Am2012-3685  0.542
2012 Kabbout M, Garcia MM, Fujimoto J, Chow C, Woods D, Koch P, Momin A, James BP, Solis LM, Behrens C, Wistuba II, Kadara H. Abstract 2177: Tumor suppressor effects of ETS2 transcriptional factor in human non-small cell lung cancer Cancer Research. 72: 2177-2177. DOI: 10.1158/1538-7445.Am2012-2177  0.6
2012 Kadara H, Fujimoto J, Yoo SY, Garcia MM, Kabbout M, Basey AL, Wang J, Coombes KR, Kim ES, Hong WK, Kalhor N, Moran C, Wistuba II. Abstract 1721: Gene expression profiling of lung tumors and matched normal airways reveals common and disparate aberrant pathways in squamous cell carcinoma and adenocarcinoma development and potential markers for detection and targets for chemoprevention in early stage lung cancer Cancer Research. 72: 1721-1721. DOI: 10.1158/1538-7445.Am2012-1721  0.612
2012 Riquelme EM, Berhens C, Suraokar M, Chow CC, Kadara H, Wistuba II, Girard L, Minna JD. Abstract 1714:EZH2HighandmiR-101Lowexpressions are associated with chemoresistance and shorter survival in patients with lung adenocarcinoma who received adjuvant chemotherapy Cancer Research. 72: 1714-1714. DOI: 10.1158/1538-7445.Am2012-1714  0.496
2012 Fujimoto J, Kadara H, Fukuoka J, Aoe K, Fujimoto N, Kishimoto T, Inai K, Hiroshima K, Suraokar M, Tsao A, Mehran R. Abstract 1711: Expression patterns of the G protein-coupled receptor, GPRC5A, in human malignant pleural mesothelioma Cancer Research. 72: 1711-1711. DOI: 10.1158/1538-7445.Am2012-1711  0.464
2012 Nunez MI, Behrens C, Woods DM, Lin H, Suraokar M, Kadara H, Hofstetter W, Kalhor N, Lee JJ, Franklin W, Stewart DJ, Wistuba II. Erratum: High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and mutation (Journal of Thoracic Oncology (2012) 7 (520-527)) Journal of Thoracic Oncology. 7. DOI: 10.1097/Jto.0B013E31825Bc1Ae  0.487
2011 Cascone T, Herynk MH, Xu L, Du Z, Kadara H, Nilsson MB, Oborn CJ, Park YY, Erez B, Jacoby JJ, Lee JS, Lin HY, Ciardiello F, Herbst RS, Langley RR, et al. Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma. The Journal of Clinical Investigation. 121: 1313-28. PMID 21436589 DOI: 10.1172/Jci42405  0.32
2011 Tang X, Kadara H, Behrens C, Liu DD, Xiao Y, Rice D, Gazdar AF, Fujimoto J, Moran C, Varella-Garcia M, Lee JJ, Hong WK, Wistuba II. Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2434-43. PMID 21257719 DOI: 10.1158/1078-0432.Ccr-10-1412  0.601
2011 Kadara H, Behrens C, Yuan P, Solis L, Liu D, Gu X, Minna JD, Lee JJ, Kim E, Hong WK, Wistuba II, Lotan R. A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1490-501. PMID 21163870 DOI: 10.1158/1078-0432.Ccr-10-2703  0.69
2011 Kadara H, Saintigny P, Fan Y, Chow C, Chu Z, Lang W, Behrens C, Gold K, Liu D, Lee JJ, Mao L, Kim ES, Hong WK, Wistuba II. Abstract 3674: Gene expression analysis of field of cancerization in early stage NSCLC patients towards development of biomarkers for personalized prevention Cancer Research. 71: 3674-3674. DOI: 10.1158/1538-7445.Am2011-3674  0.396
2011 Behrens C, Yuan P, Solis L, Saintigny P, Kadara H, Fujimoto J, Moran C, Swisher SG, Heymach JV, Wistuba II. Abstract 3196: EZH2 expression is an early event in the pathogenesis of non-small cell lung cancer (NSCLC) and correlates with tumor progression Cancer Research. 71: 3196-3196. DOI: 10.1158/1538-7445.Am2011-3196  0.522
2011 Fujimoto J, Kadara H, Behrens C, Liu D, Lee JJ, Solis LM, Kim E, Sharafkhaneh A, Wistuba II, Reuben L. Abstract 2203: Implication of GPRC5A loss in lung carcinogenesis in patients with and without chronic obstructive pulmonary disease Cellular and Molecular Biology. 71: 2203-2203. DOI: 10.1158/1538-7445.Am2011-2203  0.413
2011 Kadara H, Lotan R. Effects of natural and synthetic retinoids on the differentiation and growth of squamous cancers Signaling Pathways in Squamous Cancer. 261-282. DOI: 10.1007/978-1-4419-7203-3_13  0.518
2010 Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, Lotan R. Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor. Cancer Research. 70: 8917-26. PMID 20959490 DOI: 10.1158/0008-5472.Can-10-0518  0.673
2010 Fujimoto J, Kadara H, Men T, van Pelt C, Lotan D, Lotan R. Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice. Plos One. 5: e11847. PMID 20686609 DOI: 10.1371/Journal.Pone.0011847  0.621
2010 Kadara H, Fujimoto J, Men T, Ye X, Lotan D, Lee JS, Lotan R. A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent, and associated with survival in human lung adenocarcinomas. Neoplasia (New York, N.Y.). 12: 499-505. PMID 20563252 DOI: 10.1593/Neo.10390  0.693
2010 Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R. Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis. Cancer Prevention Research (Philadelphia, Pa.). 3: 424-37. PMID 20354164 DOI: 10.1158/1940-6207.Capr-10-0032  0.658
2010 Yuan P, Kadara H, Behrens C, Tang X, Woods D, Solis LM, Huang J, Spinola M, Dong W, Yin G, Fujimoto J, Kim E, Xie Y, Girard L, Moran C, et al. Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. Plos One. 5: e9112. PMID 20161759 DOI: 10.1371/Journal.Pone.0009112  0.609
2010 Chakravarti N, Kadara H, Yoon DJ, Shay JW, Myers JN, Lotan D, Sonenberg N, Lotan R. Differential inhibition of protein translation machinery by curcumin in normal, immortalized, and malignant oral epithelial cells. Cancer Prevention Research (Philadelphia, Pa.). 3: 331-8. PMID 20145189 DOI: 10.1158/1940-6207.Capr-09-0076  0.516
2010 Behrens C, Feng L, Kadara H, Kim HJ, Lee JJ, Mehran R, Hong WK, Lotan R, Wistuba II. Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 34-44. PMID 20028769 DOI: 10.1158/1078-0432.Ccr-09-0650  0.591
2010 Yuan P, Kadara H, Behrens C, Tang X, Woods D, Solis LM, Huang J, Spinola M, Dong W, Yin G, Fujimoto J, Kim E, Xie Y, Girard L, Moran C, et al. Abstract 5166: Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung Cancer Research. 70: 5166-5166. DOI: 10.1158/1538-7445.Am10-5166  0.62
2010 Chen Y, Deng J, Fujimoto J, Kadara H, Ye X, Men T, Lotan D, Lotan R. Abstract 4995: Loss of the lung-specific tumor suppressor Gprc5a causes persistent activation of Stat3 leading to increased survival signaling in normal and malignant lung epithelial cells Cancer Research. 70: 4995-4995. DOI: 10.1158/1538-7445.Am10-4995  0.686
2009 Kadara H, Lacroix L, Behrens C, Solis L, Gu X, Lee JJ, Tahara E, Lotan D, Hong WK, Wistuba II, Lotan R. Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system. Cancer Prevention Research (Philadelphia, Pa.). 2: 702-11. PMID 19638491 DOI: 10.1158/1940-6207.Capr-09-0084  0.7
2009 Tahara E, Kadara H, Lacroix L, Lotan D, Lotan R. Activation of protein kinase C by phorbol 12-myristate 13-acetate suppresses the growth of lung cancer cells through KLF6 induction. Cancer Biology & Therapy. 8: 801-7. PMID 19333010 DOI: 10.4161/Cbt.8.9.8186  0.641
2008 Kadara H, Tahara E, Kim HJ, Lotan D, Myers J, Lotan R. Involvement of Rac in fenretinide-induced apoptosis. Cancer Research. 68: 4416-23. PMID 18519704 DOI: 10.1158/0008-5472.Can-08-0031  0.6
2007 Pathak AK, Bhutani M, Nair AS, Ahn KS, Chakraborty A, Kadara H, Guha S, Sethi G, Aggarwal BB. Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells. Molecular Cancer Research : McR. 5: 943-55. PMID 17855663 DOI: 10.1158/1541-7786.Mcr-06-0348  0.35
2007 Kadara H, Lacroix L, Lotan D, Lotan R. Induction of endoplasmic reticulum stress by the pro-apoptotic retinoid N-(4-hydroxyphenyl)retinamide via a reactive oxygen species-dependent mechanism in human head and neck cancer cells. Cancer Biology & Therapy. 6: 705-11. PMID 17404501 DOI: 10.4161/Cbt.6.5.3963  0.452
2006 Schroeder CP, Kadara H, Lotan D, Woo JK, Lee HY, Hong WK, Lotan R. Involvement of mitochondrial and Akt signaling pathways in augmented apoptosis induced by a combination of low doses of celecoxib and N-(4-hydroxyphenyl) retinamide in premalignant human bronchial epithelial cells. Cancer Research. 66: 9762-70. PMID 17018636 DOI: 10.1158/0008-5472.Can-05-4124  0.568
2006 Kadara H, Schroeder CP, Lotan D, Pisano C, Lotan R. Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis. Cancer Biology & Therapy. 5: 518-22. PMID 16582595 DOI: 10.4161/Cbt.5.5.2602  0.502
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