JoAnne Stubbe - Publications

Affiliations: 
Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
biological chemistry
Website:
http://www.mit.edu/~chemistry/faculty/stubbe.html

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Year Citation  Score
2019 Greene BL, Stubbe J, Nocera DG. Selenocysteine Substitution into a Class I Ribonucleotide Reductase. Biochemistry. PMID 31774661 DOI: 10.1021/acs.biochem.9b00973  1
2019 Thomas WC, Brooks FP, Burnim AA, Bacik JP, Stubbe J, Kaelber JT, Chen JZ, Ando N. Convergent allostery in ribonucleotide reductase. Nature Communications. 10: 2653. PMID 31201319 DOI: 10.1038/s41467-019-10568-4  0.32
2018 Stubbe J, Seyedsayamdost MR. Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer. Biochemistry. PMID 30586288 DOI: 10.1021/acs.biochem.8b01238  1
2018 Greene BL, Stubbe J, Nocera DG. Photochemical Rescue of a Conformationally Inactivated Ribonucleotide Reductase. Journal of the American Chemical Society. PMID 30347141 DOI: 10.1021/jacs.8b07902  1
2018 Greene BL, Nocera DG, Stubbe J. Basis of dATP inhibition of RNRs. The Journal of Biological Chemistry. 293: 10413-10414. PMID 29959279 DOI: 10.1074/jbc.H118.003717  1
2018 Parker MJ, Maggiolo AO, Thomas WC, Kim A, Meisburger SP, Ando N, Boal AK, Stubbe J. An endogenous dAMP ligand in class Ib RNR promotes assembly of a noncanonical dimer for regulation by dATP. Proceedings of the National Academy of Sciences of the United States of America. PMID 29712847 DOI: 10.1073/pnas.1800356115  0.36
2018 Lee W, Kasanmascheff M, Huynh M, Quartararo A, Costentin C, Bejenke I, Nocera DG, Bennati M, Tommos C, Stubbe J. Properties of Site-Specifically Incorporated 3-Aminotyrosine in Proteins To Study Redox-Active Tyrosines: Escherichia coli Ribonucleotide Reductase as a Paradigm. Biochemistry. PMID 29630358 DOI: 10.1021/acs.biochem.8b00160  1
2018 Brignole EJ, Tsai KL, Chittuluru J, Li H, Aye Y, Penczek PA, Stubbe J, Drennan CL, Asturias F. 3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Elife. 7. PMID 29460780 DOI: 10.7554/eLife.31502  0.4
2017 Greene BL, Taguchi AT, Stubbe J, Nocera DG. Conformationally-Dynamic Radical Transfer within Ribonucleotide Reductase. Journal of the American Chemical Society. PMID 29037038 DOI: 10.1021/jacs.7b08192  1
2017 Nick TU, Ravichandran KR, Stubbe J, Kasanmascheff M, Bennati M. Spectroscopic Evidence for a H Bond Network at Y356 Located at the Subunit Interface of Active E. coli Ribonucleotide Reductase. Biochemistry. PMID 28640584 DOI: 10.1021/acs.biochem.7b00462  0.68
2017 Li H, Stümpfig M, Zhang C, An X, Stubbe J, Lill R, Huang M. The diferric-tyrosyl radical cluster of ribonucleotide reductase and cytosolic iron-sulfur clusters have distinct and similar biogenesis requirements. The Journal of Biological Chemistry. PMID 28515324 DOI: 10.1074/jbc.M117.786178  0.48
2017 Lin Q, Parker MJ, Taguchi AT, Ravichandran K, Kim A, Kang G, Shao J, Drennan CL, Stubbe J. Glutamate 52-β at the α/β Subunit Interface of E. coli Class Ia Ribonucleotide Reductase is essential for Conformational Gating of Radical Transfer. The Journal of Biological Chemistry. PMID 28377505 DOI: 10.1074/jbc.M117.783092  0.64
2017 Ravichandran KR, Zong AB, Taguchi AT, Nocera DG, Stubbe J, Tommos C. Formal reduction potentials of difluorotyrosine and trifluorotyrosine protein residues: Defining the thermodynamics of multistep radical transfer. Journal of the American Chemical Society. PMID 28171730 DOI: 10.1021/jacs.6b11011  1
2017 Ravichandran KR, Minnihan EC, Lin Q, Yokoyama K, Taguchi AT, Shao J, Nocera DG, Stubbe J. Glutamate 350 plays an essential role in conformational gating of long range radical transport in E. coli class Ia ribonucleotide reductase. Biochemistry. PMID 28103007 DOI: 10.1021/acs.biochem.6b01145  1
2016 Kasanmascheff M, Lee W, Nick TU, Stubbe J, Bennati M. Radical transfer in ribonucleotide reductase: a NHY/RA-α mutant unmasks a new conformation of the pathway residue 731. Chemical Science. 7: 2170-2178. PMID 29899944 DOI: 10.1039/c5sc03460d  0.44
2016 Ravichandran KR, Taguchi AT, Wei Y, Tommos C, Nocera DG, Stubbe J. A >200 meV Uphill Thermodynamic Landscape for Radical Transport in Escherichia coli Ribonucleotide Reductase Determined Using Fluorotyrosine-Substituted Enzymes. Journal of the American Chemical Society. 138: 13706-13716. PMID 28068088 DOI: 10.1021/jacs.6b08200  1
2016 Wittenborn EC, Jost M, Wei Y, Stubbe J, Drennan CL. Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator. The Journal of Biological Chemistry. PMID 27742839 DOI: 10.1074/jbc.M116.756833  0.72
2016 Ravichandran KR, Taguchi AT, Wei Y, Tommos C, Nocera DG, Stubbe J. A >200 meV uphill thermodynamic landscape for radical transport in E. coli ribonucleotide reductase determined using fluorotyrosine-substituted enzymes. Journal of the American Chemical Society. PMID 27649294 DOI: 10.1021/jacs.6b08200  1
2016 Oyala PH, Ravichandran KR, Funk MA, Stucky PA, Stich TA, Drennan CL, Britt RD, Stubbe J. Biophysical characterization of fluorotyrosine probes site-specifically incorporated into enzymes: E. coli ribonucleotide reductase as an example. Journal of the American Chemical Society. PMID 27276098 DOI: 10.1021/jacs.6b03605  0.68
2016 Olshansky L, Greene BL, Finkbeiner C, Stubbe J, Nocera DG. Photochemical Generation of a Tryptophan Radical within the Subunit Interface of Ribonucleotide Reductase. Biochemistry. PMID 27159163 DOI: 10.1021/acs.biochem.6b00292  1
2016 Ando N, Li H, Brignole EJ, Thompson S, McLaughlin MI, Page JE, Asturias FJ, Stubbe J, Drennan CL. Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer. Biochemistry. PMID 26727048 DOI: 10.1021/acs.biochem.5b01207  0.4
2015 Olshansky L, Stubbe J, Nocera DG. Charge Transfer Dynamics at the α/β Subunit Interface of a Photo-chemical Ribonucleotide Reductase. Journal of the American Chemical Society. PMID 26710997 DOI: 10.1021/jacs.5b09259  1
2015 Doan PE, Shanmugam M, Stubbe J, Hoffman BM. Composition and Structure of the Inorganic Core of Relaxed Intermediate X(Y122F) of Escherichia coli Ribonucleotide Reductase. Journal of the American Chemical Society. PMID 26636616 DOI: 10.1021/jacs.5b10763  1
2015 Wei Y, Li B, Prakash D, Ferry JG, Elliott SJ, Stubbe J. A ferredoxin disulfide reductase delivers electrons to the Methanosarcina barkeri class III ribonucleotide reductase. Biochemistry. PMID 26536144 DOI: 10.1021/acs.biochem.5b01092  1
2015 Song DY, Pizano AA, Holder PG, Stubbe J, Nocera DG. Direct Interfacial Y731 Oxidation in α2 by a Photoβ2 Subunit of E. coli Class Ia Ribonucleotide Reductase. Chemical Science (Royal Society of Chemistry : 2010). 6: 4519-4524. PMID 26504513 DOI: 10.1039/C5SC01125F  1
2015 Ravichandran KR, Minnihan EC, Wei Y, Nocera DG, Stubbe J. Reverse electron transfer completes the catalytic cycle in a 2,3,5-trifluorotyrosine-substituted ribonucleotide reductase. Journal of the American Chemical Society. PMID 26492582 DOI: 10.1021/jacs.5b09189  1
2015 Koo BJ, Huynh M, Halbach RL, Stubbe J, Nocera DG. Modulation of Phenol Oxidation in Cofacial Dyads. Journal of the American Chemical Society. 137: 11860-3. PMID 26305909 DOI: 10.1021/jacs.5b05955  1
2015 Nick TU, Lee W, Kossmann S, Neese F, Stubbe J, Bennati M. Hydrogen bond network between amino acid radical intermediates on the proton-coupled electron transfer pathway of E. coli α2 ribonucleotide reductase. Journal of the American Chemical Society. 137: 289-98. PMID 25516424 DOI: 10.1021/ja510513z  1
2015 Song DY, Pizano AA, Holder PG, Stubbe J, Nocera DG. Direct interfacial Y731 oxidation in α2 by a photoβ2 subunit of E. coli class Ia ribonucleotide reductase Chemical Science. 6: 4519-4524. DOI: 10.1039/c5sc01125f  1
2014 Olshansky L, Pizano AA, Wei Y, Stubbe J, Nocera DG. Kinetics of hydrogen atom abstraction from substrate by an active site thiyl radical in ribonucleotide reductase. Journal of the American Chemical Society. 136: 16210-6. PMID 25353063 DOI: 10.1021/ja507313w  1
2014 Huang M, Parker MJ, Stubbe J. Choosing the right metal: case studies of class I ribonucleotide reductases. The Journal of Biological Chemistry. 289: 28104-11. PMID 25160629 DOI: 10.1074/jbc.R114.596684  1
2014 Wei Y, Funk MA, Rosado LA, Baek J, Drennan CL, Stubbe J. The class III ribonucleotide reductase from Neisseria bacilliformis can utilize thioredoxin as a reductant. Proceedings of the National Academy of Sciences of the United States of America. 111: E3756-65. PMID 25157154 DOI: 10.1073/pnas.1414396111  1
2014 Zhang W, Shrestha R, Buckley RM, Jewell J, Bossmann SH, Stubbe J, Li P. Mechanistic insight with HBCH2CoA as a probe to polyhydroxybutyrate (PHB) synthases. Acs Chemical Biology. 9: 1773-9. PMID 24896226 DOI: 10.1021/cb5002735  1
2014 Wei Y, Mathies G, Yokoyama K, Chen J, Griffin RG, Stubbe J. A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase. Journal of the American Chemical Society. 136: 9001-13. PMID 24827372 DOI: 10.1021/ja5030194  1
2014 Zhang Y, Li H, Zhang C, An X, Liu L, Stubbe J, Huang M. Conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis. Proceedings of the National Academy of Sciences of the United States of America. 111: E1695-704. PMID 24733891 DOI: 10.1073/pnas.1405204111  1
2014 Parker MJ, Zhu X, Stubbe J. Bacillus subtilis class Ib ribonucleotide reductase: high activity and dynamic subunit interactions. Biochemistry. 53: 766-76. PMID 24401092 DOI: 10.1021/bi401056e  1
2014 Makhlynets O, Boal AK, Rhodes DV, Kitten T, Rosenzweig AC, Stubbe J. Streptococcus sanguinis class Ib ribonucleotide reductase: high activity with both iron and manganese cofactors and structural insights. The Journal of Biological Chemistry. 289: 6259-72. PMID 24381172 DOI: 10.1074/jbc.M113.533554  1
2014 Rhodes DV, Crump KE, Makhlynets O, Snyder M, Ge X, Xu P, Stubbe J, Kitten T. Genetic characterization and role in virulence of the ribonucleotide reductases of Streptococcus sanguinis. The Journal of Biological Chemistry. 289: 6273-87. PMID 24381171 DOI: 10.1074/jbc.M113.533620  1
2013 Ravichandran KR, Liang L, Stubbe J, Tommos C. Formal reduction potential of 3,5-difluorotyrosine in a structured protein: insight into multistep radical transfer. Biochemistry. 52: 8907-15. PMID 24228716 DOI: 10.1021/bi401494f  1
2013 Pizano AA, Olshansky L, Holder PG, Stubbe J, Nocera DG. Modulation of Y356 photooxidation in E. coli class Ia ribonucleotide reductase by Y731 across the α2:β2 interface. Journal of the American Chemical Society. 135: 13250-3. PMID 23927429 DOI: 10.1021/ja405498e  1
2013 Minnihan EC, Nocera DG, Stubbe J. Reversible, long-range radical transfer in E. coli class Ia ribonucleotide reductase. Accounts of Chemical Research. 46: 2524-35. PMID 23730940 DOI: 10.1021/ar4000407  1
2013 Wörsdörfer B, Conner DA, Yokoyama K, Livada J, Seyedsayamdost M, Jiang W, Silakov A, Stubbe J, Bollinger JM, Krebs C. Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer. Journal of the American Chemical Society. 135: 8585-93. PMID 23676140 DOI: 10.1021/ja401342s  0.68
2013 Offenbacher AR, Minnihan EC, Stubbe J, Barry BA. Redox-linked changes to the hydrogen-bonding network of ribonucleotide reductase β2. Journal of the American Chemical Society. 135: 6380-3. PMID 23594029 DOI: 10.1021/ja3032949  1
2013 Zhang Y, An X, Stubbe J, Huang M. Investigation of in vivo roles of the C-terminal tails of the small subunit (ββ') of Saccharomyces cerevisiae ribonucleotide reductase: contribution to cofactor formation and intersubunit association within the active holoenzyme. The Journal of Biological Chemistry. 288: 13951-9. PMID 23532842 DOI: 10.1074/jbc.M113.467001  1
2013 Dowhan W, Nikaido H, Stubbe J, Kozarich JW, Wickner WT, Russell DW, Garrett TA, Brozek K, Modrich P. Christian Raetz: scientist and friend extraordinaire. Annual Review of Biochemistry. 82: 1-24. PMID 23472605 DOI: 10.1146/annurev-biochem-012512-091530  1
2013 Minnihan EC, Ando N, Brignole EJ, Olshansky L, Chittuluru J, Asturias FJ, Drennan CL, Nocera DG, Stubbe J. Generation of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductase. Proceedings of the National Academy of Sciences of the United States of America. 110: 3835-40. PMID 23431160 DOI: 10.1073/pnas.1220691110  1
2013 Cotruvo JA, Stich TA, Britt RD, Stubbe J. Mechanism of assembly of the dimanganese-tyrosyl radical cofactor of class Ib ribonucleotide reductase: enzymatic generation of superoxide is required for tyrosine oxidation via a Mn(III)Mn(IV) intermediate. Journal of the American Chemical Society. 135: 4027-39. PMID 23402532 DOI: 10.1021/ja312457t  1
2012 Argirevi? T, Riplinger C, Stubbe J, Neese F, Bennati M. ENDOR spectroscopy and DFT calculations: evidence for the hydrogen-bond network within α2 in the PCET of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 134: 17661-70. PMID 23072506 DOI: 10.1021/ja3071682  1
2012 Cotruvo JA, Stubbe J. Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study. Metallomics : Integrated Biometal Science. 4: 1020-36. PMID 22991063 DOI: 10.1039/c2mt20142a  1
2012 Aye Y, Long MJ, Stubbe J. Mechanistic studies of semicarbazone triapine targeting human ribonucleotide reductase in vitro and in mammalian cells: tyrosyl radical quenching not involving reactive oxygen species. The Journal of Biological Chemistry. 287: 35768-78. PMID 22915594 DOI: 10.1074/jbc.M112.396911  1
2012 Aye Y, Brignole EJ, Long MJ, Chittuluru J, Drennan CL, Asturias FJ, Stubbe J. Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers. Chemistry & Biology. 19: 799-805. PMID 22840768 DOI: 10.1016/j.chembiol.2012.05.015  1
2012 Zimanyi CM, Ando N, Brignole EJ, Asturias FJ, Stubbe J, Drennan CL. Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase. Structure (London, England : 1993). 20: 1374-83. PMID 22727814 DOI: 10.1016/j.str.2012.05.009  1
2012 Boal AK, Cotruvo JA, Stubbe J, Rosenzweig AC. The dimanganese(II) site of Bacillus subtilis class Ib ribonucleotide reductase. Biochemistry. 51: 3861-71. PMID 22443445 DOI: 10.1021/bi201925t  1
2012 Cho M, Brigham CJ, Sinskey AJ, Stubbe J. Purification of polyhydroxybutyrate synthase from its native organism, Ralstonia eutropha: implications for the initiation and elongation of polymer formation in vivo. Biochemistry. 51: 2276-88. PMID 22369488 DOI: 10.1021/bi2013596  1
2012 Beeby M, Cho M, Stubbe J, Jensen GJ. Growth and localization of polyhydroxybutyrate granules in Ralstonia eutropha. Journal of Bacteriology. 194: 1092-9. PMID 22178974 DOI: 10.1128/JB.06125-11  1
2012 Pizano AA, Lutterman DA, Holder PG, Teets TS, Stubbe J, Nocera DG. Photo-ribonucleotide reductase β2 by selective cysteine labeling with a radical phototrigger. Proceedings of the National Academy of Sciences of the United States of America. 109: 39-43. PMID 22171005 DOI: 10.1073/pnas.1115778108  1
2012 Holder PG, Pizano AA, Anderson BL, Stubbe J, Nocera DG. Deciphering radical transport in the large subunit of class I ribonucleotide reductase. Journal of the American Chemical Society. 134: 1172-80. PMID 22121977 DOI: 10.1021/ja209016j  1
2011 Ando N, Brignole EJ, Zimanyi CM, Funk MA, Yokoyama K, Asturias FJ, Stubbe J, Drennan CL. Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase. Proceedings of the National Academy of Sciences of the United States of America. 108: 21046-51. PMID 22160671 DOI: 10.1073/pnas.1112715108  1
2011 Wickner WT, Stubbe J, Hirschberg CB, Garrett T, Dowhan W. Chris Raetz, scientist and enduring friend. Proceedings of the National Academy of Sciences of the United States of America. 108: 17255-6. PMID 21969572 DOI: 10.1073/pnas.1114405108  1
2011 Yokoyama K, Smith AA, Corzilius B, Griffin RG, Stubbe J. Equilibration of tyrosyl radicals (Y356•, Y731•, Y730•) in the radical propagation pathway of the Escherichia coli class Ia ribonucleotide reductase. Journal of the American Chemical Society. 133: 18420-32. PMID 21967342 DOI: 10.1021/ja207455k  1
2011 Zhang Y, Liu L, Wu X, An X, Stubbe J, Huang M. Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: requirement of Rnr4 and contribution of Grx3/4 AND Dre2 proteins. The Journal of Biological Chemistry. 286: 41499-509. PMID 21931161 DOI: 10.1074/jbc.M111.294074  1
2011 Minnihan EC, Young DD, Schultz PG, Stubbe J. Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase. Journal of the American Chemical Society. 133: 15942-5. PMID 21913683 DOI: 10.1021/ja207719f  1
2011 Thompson LR, Zeng Q, Kelly L, Huang KH, Singer AU, Stubbe J, Chisholm SW. Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism. Proceedings of the National Academy of Sciences of the United States of America. 108: E757-64. PMID 21844365 DOI: 10.1073/pnas.1102164108  1
2011 Aye Y, Stubbe J. Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit. Proceedings of the National Academy of Sciences of the United States of America. 108: 9815-20. PMID 21628579 DOI: 10.1073/pnas.1013274108  1
2011 Minnihan EC, Seyedsayamdost MR, Uhlin U, Stubbe J. Kinetics of radical intermediate formation and deoxynucleotide production in 3-aminotyrosine-substituted Escherichia coli ribonucleotide reductases. Journal of the American Chemical Society. 133: 9430-40. PMID 21612216 DOI: 10.1021/ja201640n  1
2011 Zhang Y, Stubbe J. Bacillus subtilis class Ib ribonucleotide reductase is a dimanganese(III)-tyrosyl radical enzyme. Biochemistry. 50: 5615-23. PMID 21561096 DOI: 10.1021/bi200348q  1
2011 Stubbe J. Biochemistry. The two faces of SAM. Science (New York, N.Y.). 332: 544-5. PMID 21527702 DOI: 10.1126/science.1204209  1
2011 Cotruvo JA, Stubbe J. Class I ribonucleotide reductases: metallocofactor assembly and repair in vitro and in vivo. Annual Review of Biochemistry. 80: 733-67. PMID 21456967 DOI: 10.1146/annurev-biochem-061408-095817  1
2011 Cotruvo JA, Stubbe J. Escherichia coli class Ib ribonucleotide reductase contains a dimanganese(III)-tyrosyl radical cofactor in vivo. Biochemistry. 50: 1672-81. PMID 21250660 DOI: 10.1021/bi101881d  1
2011 Stubbe J, Cotruvo JA. Control of metallation and active cofactor assembly in the class Ia and Ib ribonucleotide reductases: diiron or dimanganese? Current Opinion in Chemical Biology. 15: 284-90. PMID 21216656 DOI: 10.1016/j.cbpa.2010.12.001  1
2011 Seyedsayamdost MR, Yee CS, Stubbe J. Use of 2,3,5-F(3)Y-β2 and 3-NH(2)Y-α2 to study proton-coupled electron transfer in Escherichia coli ribonucleotide reductase. Biochemistry. 50: 1403-11. PMID 21182280 DOI: 10.1021/bi101319v  1
2011 Holder PG, Nocera DG, Francis MB, Stubbe J. Guiding and measuring electron transfers in biomolecules: Lessons for photovoltaics, materials, and medicine Acs National Meeting Book of Abstracts 1
2010 Yokoyama K, Uhlin U, Stubbe J. A hot oxidant, 3-NO2Y122 radical, unmasks conformational gating in ribonucleotide reductase. Journal of the American Chemical Society. 132: 15368-79. PMID 20929229 DOI: 10.1021/ja1069344  1
2010 Mühlenhoff U, Molik S, Godoy JR, Uzarska MA, Richter N, Seubert A, Zhang Y, Stubbe J, Pierrel F, Herrero E, Lillig CH, Lill R. Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metabolism. 12: 373-85. PMID 20889129 DOI: 10.1016/j.cmet.2010.08.001  1
2010 Boal AK, Cotruvo JA, Stubbe J, Rosenzweig AC. Structural basis for activation of class Ib ribonucleotide reductase. Science (New York, N.Y.). 329: 1526-30. PMID 20688982 DOI: 10.1126/science.1190187  1
2010 Yokoyama K, Uhlin U, Stubbe J. Site-specific incorporation of 3-nitrotyrosine as a probe of pKa perturbation of redox-active tyrosines in ribonucleotide reductase. Journal of the American Chemical Society. 132: 8385-97. PMID 20518462 DOI: 10.1021/ja101097p  1
2010 Lohman GJ, Stubbe J. Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: covalent modification. Biochemistry. 49: 1404-17. PMID 20088569 DOI: 10.1021/bi902132u  1
2010 Lohman GJ, Gerfen GJ, Stubbe J. Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical. Biochemistry. 49: 1396-403. PMID 20088568 DOI: 10.1021/bi9021318  1
2010 Cotruvo JA, Stubbe J. An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase. Biochemistry. 49: 1297-309. PMID 20070127 DOI: 10.1021/bi902106n  1
2010 Sicoli G, Argirevi? T, Stubbe J, Tkach I, Bennati M. Effects in 94 GHz orientation-selected PELDOR on a rigid pair of radicals with Non-collinear axes Applied Magnetic Resonance. 37: 539-548. DOI: 10.1007/s00723-009-0094-3  1
2009 Minnihan EC, Yokoyama K, Stubbe J. Unnatural amino acids: better than the real things? F1000 Biology Reports. 1: 88. PMID 20948602 DOI: 10.3410/B1-88  0.8
2009 Minnihan EC, Seyedsayamdost MR, Stubbe J. Use of 3-aminotyrosine to examine the pathway dependence of radical propagation in Escherichia coli ribonucleotide reductase. Biochemistry. 48: 12125-32. PMID 19916558 DOI: 10.1021/bi901439w  1
2009 Wang J, Lohman GJ, Stubbe J. Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphate. Biochemistry. 48: 11612-21. PMID 19899807 DOI: 10.1021/bi901588z  1
2009 Artin E, Wang J, Lohman GJ, Yokoyama K, Yu G, Griffin RG, Bar G, Stubbe J. Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant. Biochemistry. 48: 11622-9. PMID 19899770 DOI: 10.1021/bi901590q  1
2009 Seyedsayamdost MR, Argirevi? T, Minnihan EC, Stubbe J, Bennati M. Structural examination of the transient 3-aminotyrosyl radical on the PCET pathway of E. coli ribonucleotide reductase by multifrequency EPR spectroscopy. Journal of the American Chemical Society. 131: 15729-38. PMID 19821570 DOI: 10.1021/ja903879w  1
2009 Li P, Chakraborty S, Stubbe J. Detection of covalent and noncovalent intermediates in the polymerization reaction catalyzed by a C149S class III polyhydroxybutyrate synthase. Biochemistry. 48: 9202-11. PMID 19711985 DOI: 10.1021/bi901329b  1
2009 Seyedsayamdost MR, Stubbe J. Replacement of Y730 and Y731 in the alpha2 subunit of Escherichia coli ribonucleotide reductase with 3-aminotyrosine using an evolved suppressor tRNA/tRNA-synthetase pair. Methods in Enzymology. 462: 45-76. PMID 19632469 DOI: 10.1016/S0076-6879(09)62003-6  1
2009 Offenbacher AR, Vassiliev IR, Seyedsayamdost MR, Stubbe J, Barry BA. Redox-linked structural changes in ribonucleotide reductase. Journal of the American Chemical Society. 131: 7496-7. PMID 19489635 DOI: 10.1021/ja901908j  1
2009 Reece SY, Lutterman DA, Seyedsayamdost MR, Stubbe J, Nocera DG. Re(bpy)(CO)3CN as a probe of conformational flexibility in a photochemical ribonucleotide reductase. Biochemistry. 48: 5832-8. PMID 19402704 DOI: 10.1021/bi9005804  1
2009 Kim Y, Gabbaï FP. Cationic boranes for the complexation of fluoride ions in water below the 4 ppm maximum contaminant level. Journal of the American Chemical Society. 131: 3363-9. PMID 19256571 DOI: 10.1021/ja8091467  1
2009 Shanmugam M, Doan PE, Lees NS, Stubbe J, Hoffman BM. Identification of protonated oxygenic ligands of ribonucleotide reductase intermediate X. Journal of the American Chemical Society. 131: 3370-6. PMID 19220056 DOI: 10.1021/ja809223s  1
2009 Zipse H, Artin E, Wnuk S, Lohman GJ, Martino D, Griffin RG, Kacprzak S, Kaupp M, Hoffman B, Bennati M, Stubbe J, Lees N. Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 131: 200-11. PMID 19128178 DOI: 10.1021/ja806693s  1
2008 Marletta MA, Stubbe J. Catalysis and regulation. Editorial overview. Current Opinion in Structural Biology. 18: 641-3. PMID 19059103 DOI: 10.1016/j.sbi.2008.11.006  1
2008 Hassan AQ, Wang Y, Plate L, Stubbe J. Methodology to probe subunit interactions in ribonucleotide reductases. Biochemistry. 47: 13046-55. PMID 19012414 DOI: 10.1021/bi8012559  1
2008 Lee YD, Wang J, Stubbe J, Elledge SJ. Dif1 is a DNA-damage-regulated facilitator of nuclear import for ribonucleotide reductase. Molecular Cell. 32: 70-80. PMID 18851834 DOI: 10.1016/j.molcel.2008.08.018  1
2008 Cotruvo JA, Stubbe J. NrdI, a flavodoxin involved in maintenance of the diferric-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase. Proceedings of the National Academy of Sciences of the United States of America. 105: 14383-8. PMID 18799738 DOI: 10.1073/pnas.0807348105  1
2008 Hassan AQ, Stubbe J. Mapping the subunit interface of ribonucleotide reductase (RNR) using photo cross-linking. Bioorganic & Medicinal Chemistry Letters. 18: 5923-5. PMID 18762419 DOI: 10.1016/j.bmcl.2008.08.048  1
2008 Morar M, Hoskins AA, Stubbe J, Ealick SE. Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation. Biochemistry. 47: 7816-30. PMID 18597481 DOI: 10.1021/bi800329p  1
2008 Chen J, Ghorai MK, Kenney G, Stubbe J. Mechanistic studies on bleomycin-mediated DNA damage: multiple binding modes can result in double-stranded DNA cleavage. Nucleic Acids Research. 36: 3781-90. PMID 18492718 DOI: 10.1093/nar/gkn302  1
2008 Hristova D, Wu CH, Jiang W, Krebs C, Stubbe J. Importance of the maintenance pathway in the regulation of the activity of Escherichia coli ribonucleotide reductase. Biochemistry. 47: 3989-99. PMID 18314964 DOI: 10.1021/bi702408k  1
2008 Chen J, Dupradeau FY, Case DA, Turner CJ, Stubbe J. DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics. Nucleic Acids Research. 36: 253-62. PMID 18025040 DOI: 10.1093/nar/gkm622  1
2007 Seyedsayamdost MR, Chan CT, Mugnaini V, Stubbe J, Bennati M. PELDOR spectroscopy with DOPA-beta2 and NH2Y-alpha2s: distance measurements between residues involved in the radical propagation pathway of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 129: 15748-9. PMID 18047343 DOI: 10.1021/ja076459b  1
2007 Seyedsayamdost MR, Xie J, Chan CT, Schultz PG, Stubbe J. Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation. Journal of the American Chemical Society. 129: 15060-71. PMID 17990884 DOI: 10.1021/ja076043y  1
2007 Chen B, Zhou X, Taghizadeh K, Chen J, Stubbe J, Dedon PC. GC/MS methods to quantify the 2-deoxypentos-4-ulose and 3'-phosphoglycolate pathways of 4' oxidation of 2-deoxyribose in DNA: application to DNA damage produced by gamma radiation and bleomycin. Chemical Research in Toxicology. 20: 1701-8. PMID 17944541 DOI: 10.1021/tx700164y  1
2007 Reece SY, Seyedsayamdost MR, Stubbe J, Nocera DG. Direct observation of a transient tyrosine radical competent for initiating turnover in a photochemical ribonucleotide reductase. Journal of the American Chemical Society. 129: 13828-30. PMID 17944464 DOI: 10.1021/ja074452o  1
2007 Wu CH, Jiang W, Krebs C, Stubbe J. YfaE, a ferredoxin involved in diferric-tyrosyl radical maintenance in Escherichia coli ribonucleotide reductase. Biochemistry. 46: 11577-88. PMID 17880186 DOI: 10.1021/bi7012454  1
2007 Wang J, Lohman GJ, Stubbe J. Enhanced subunit interactions with gemcitabine-5'-diphosphate inhibit ribonucleotide reductases. Proceedings of the National Academy of Sciences of the United States of America. 104: 14324-9. PMID 17726094 DOI: 10.1073/pnas.0706803104  1
2007 Stubbe J. Computational biochemistry: models of transition. Nature. 448: 762-3. PMID 17700688 DOI: 10.1038/448762a  1
2007 Reece SY, Seyedsayamdost MR, Stubbe J, Nocera DG. Photoactive peptides for light-initiated tyrosyl radical generation and transport into ribonucleotide reductase. Journal of the American Chemical Society. 129: 8500-9. PMID 17567129 DOI: 10.1021/ja0704434  1
2007 Seyedsayamdost MR, Yee CS, Stubbe J. Site-specific incorporation of fluorotyrosines into the R2 subunit of E. coli ribonucleotide reductase by expressed protein ligation. Nature Protocols. 2: 1225-35. PMID 17546018 DOI: 10.1038/nprot.2007.159  1
2007 Chen J, Dupradeau FY, Case DA, Turner CJ, Stubbe J. Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites. Biochemistry. 46: 3096-107. PMID 17323932 DOI: 10.1021/bi6024269  1
2007 Hoskins AA, Morar M, Kappock TJ, Mathews II, Zaugg JB, Barder TE, Peng P, Okamoto A, Ealick SE, Stubbe J. N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis. Biochemistry. 46: 2842-55. PMID 17298082 DOI: 10.1021/bi602436g  1
2007 Seyedsayamdost MR, Stubbe J. Forward and reverse electron transfer with the Y356DOPA-beta2 heterodimer of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 129: 2226-7. PMID 17279757 DOI: 10.1021/ja0685607  1
2006 Morar M, Anand R, Hoskins AA, Stubbe J, Ealick SE. Complexed structures of formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima describe a novel ATP binding protein superfamily. Biochemistry. 45: 14880-95. PMID 17154526 DOI: 10.1021/bi061591u  1
2006 Reece SY, Seyedsayamdost MR, Stubbe J, Nocera DG. Electron transfer reactions of fluorotyrosyl radicals. Journal of the American Chemical Society. 128: 13654-5. PMID 17044670 DOI: 10.1021/ja0636688  1
2006 Ortigosa AD, Hristova D, Perlstein DL, Zhang Z, Huang M, Stubbe J. Determination of the in vivo stoichiometry of tyrosyl radical per betabeta' in Saccharomyces cerevisiae ribonucleotide reductase. Biochemistry. 45: 12282-94. PMID 17014081 DOI: 10.1021/bi0610404  1
2006 Denysenkov VP, Prisner TF, Stubbe J, Bennati M. High-field pulsed electron-electron double resonance spectroscopy to determine the orientation of the tyrosyl radicals in ribonucleotide reductase Proceedings of the National Academy of Sciences of the United States of America. 103: 13386-13390. PMID 16938868 DOI: 10.1073/pnas.0605851103  1
2006 Reece SY, Hodgkiss JM, Stubbe J, Nocera DG. Proton-coupled electron transfer: the mechanistic underpinning for radical transport and catalysis in biology. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 1351-64. PMID 16873123 DOI: 10.1098/rstb.2006.1874  1
2006 Seyedsayamdost MR, Stubbe J. Site-specific replacement of Y356 with 3,4-dihydroxyphenylalanine in the beta2 subunit of E. coli ribonucleotide reductase. Journal of the American Chemical Society. 128: 2522-3. PMID 16492021 DOI: 10.1021/ja057776q  1
2006 Seyedsayamdost MR, Reece SY, Nocera DG, Stubbe J. Mono-, di-, tri-, and tetra-substituted fluorotyrosines: new probes for enzymes that use tyrosyl radicals in catalysis. Journal of the American Chemical Society. 128: 1569-79. PMID 16448128 DOI: 10.1021/ja055926r  1
2006 Seyedsayamdost MR, Yee CS, Reece SY, Nocera DG, Stubbe J. pH Rate profiles of FnY356-R2s (n = 2, 3, 4) in Escherichia coli ribonucleotide reductase: evidence that Y356 is a redox-active amino acid along the radical propagation pathway. Journal of the American Chemical Society. 128: 1562-8. PMID 16448127 DOI: 10.1021/ja055927j  1
2006 Zhang Z, An X, Yang K, Perlstein DL, Hicks L, Kelleher N, Stubbe J, Huang M. Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 1422-7. PMID 16432237 DOI: 10.1073/pnas.0510516103  1
2005 Perlstein DL, Ge J, Ortigosa AD, Robblee JH, Zhang Z, Huang M, Stubbe J. The active form of the Saccharomyces cerevisiae ribonucleotide reductase small subunit is a heterodimer in vitro and in vivo. Biochemistry. 44: 15366-77. PMID 16285741 DOI: 10.1021/bi051616+  1
2005 Bennati M, Robblee JH, Mugnaini V, Stubbe J, Freed JH, Borbat P. EPR distance measurements support a model for long-range radical initiation in E. coli ribonucleotide reductase. Journal of the American Chemical Society. 127: 15014-5. PMID 16248626 DOI: 10.1021/ja054991y  1
2005 Lawrence AG, Choi J, Rha C, Stubbe J, Sinskey AJ. In vitro analysis of the chain termination reaction in the synthesis of poly-(R)-beta-hydroxybutyrate by the class III synthase from Allochromatium vinosum. Biomacromolecules. 6: 2113-9. PMID 16004452 DOI: 10.1021/bm0501048  1
2005 Stubbe J, Tian J, He A, Sinskey AJ, Lawrence AG, Liu P. Nontemplate-dependent polymerization processes: polyhydroxyalkanoate synthases as a paradigm. Annual Review of Biochemistry. 74: 433-80. PMID 15952894 DOI: 10.1146/annurev.biochem.74.082803.133013  1
2005 Tian J, Sinskey AJ, Stubbe J. Class III polyhydroxybutyrate synthase: Involvement in chain termination and reinitiation Biochemistry. 44: 8369-8377. PMID 15938626 DOI: 10.1021/bi050331u  1
2005 Lawrence AG, Schoenheit J, He A, Tian J, Liu P, Stubbe J, Sinskey AJ. Transcriptional analysis of Ralstonia eutropha genes related to poly-(R)-3-hydroxybutyrate homeostasis during batch fermentation. Applied Microbiology and Biotechnology. 68: 663-72. PMID 15924243 DOI: 10.1007/s00253-005-1969-3  1
2005 Fritscher J, Artin E, Wnuk S, Bar G, Robblee JH, Kacprzak S, Kaupp M, Griffin RG, Bennati M, Stubbe J. Structure of the nitrogen-centered radical formed during inactivation of E. coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine-5'-diphosphate: trapping of the 3'-ketonucleotide. Journal of the American Chemical Society. 127: 7729-38. PMID 15913363 DOI: 10.1021/ja043111x  1
2005 Tian J, He A, Lawrence AG, Liu P, Watson N, Sinskey AJ, Stubbe J. Analysis of transient polyhydroxybutyrate production in Wautersia eutropha H16 by quantitative Western analysis and transmission electron microscopy. Journal of Bacteriology. 187: 3825-32. PMID 15901707 DOI: 10.1128/JB.187.11.3825-3832.2005  1
2005 Tian J, Sinskey AJ, Stubbe J. Kinetic studies of polyhydroxybutyrate granule formation in Wautersia eutropha H16 by transmission electron microscopy Journal of Bacteriology. 187: 3814-3824. PMID 15901706 DOI: 10.1128/JB.187.11.3814-3824.2005  1
2005 Reece SY, Stubbe J, Nocera DG. pH Dependence of charge transfer between tryptophan and tyrosine in dipeptides. Biochimica Et Biophysica Acta. 1706: 232-8. PMID 15694351 DOI: 10.1016/j.bbabio.2004.11.011  1
2005 Chen J, Stubbe J. Bleomycins: Towards better therapeutics Nature Reviews Cancer. 5: 102-112. PMID 15685195 DOI: 10.1038/nrc1547  1
2005 Tian J, Sinskey AJ, Stubbe J. Detection of intermediates from the polymerization reaction catalyzed by a D302A mutant of class III polyhydroxyalkanoate (PHA) synthase Biochemistry. 44: 1495-1503. PMID 15683234 DOI: 10.1021/bi047734z  1
2005 Davydov R, Behrouzian B, Smoukov S, Stubbe J, Hoffman BM, Shanklin J. Effect of substrate on the diiron(III) site in stearoyl acyl carrier protein Δ9-desaturase as disclosed by cryoreduction electron paramagnetic resonance/electron nuclear double resonance spectroscopy Biochemistry. 44: 1309-1315. PMID 15667224 DOI: 10.1021/bi048599t  1
2005 Denysenkov VP, Prisner TF, Stubbe J, Bennati M. High-frequency 180 GHz PELDOR Applied Magnetic Resonance. 29: 375-384.  1
2004 Chang MC, Yee CS, Nocera DG, Stubbe J. Site-specific replacement of a conserved tyrosine in ribonucleotide reductase with an aniline amino acid: a mechanistic probe for a redox-active tyrosine. Journal of the American Chemical Society. 126: 16702-3. PMID 15612690 DOI: 10.1021/ja044124d  1
2004 Anand R, Hoskins AA, Bennett EM, Sintchak MD, Stubbe J, Ealick SE. A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex. Biochemistry. 43: 10343-52. PMID 15301532 DOI: 10.1021/bi0491292  1
2004 Anand R, Hoskins AA, Stubbe J, Ealick SE. Domain organization of Salmonella typhimurium formylglycinamide ribonucleotide amidotransferase revealed by X-ray crystallography. Biochemistry. 43: 10328-42. PMID 15301531 DOI: 10.1021/bi0491301  1
2004 Hoskins AA, Anand R, Ealick SE, Stubbe J. The formylglycinamide ribonucleotide amidotransferase complex from Bacillus subtilis: metabolite-mediated complex formation. Biochemistry. 43: 10314-27. PMID 15301530 DOI: 10.1021/bi049127h  1
2004 Sommerhalter M, Voegtli WC, Perlstein DL, Ge J, Stubbe J, Rosenzweig AC. Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers. Biochemistry. 43: 7736-42. PMID 15196016 DOI: 10.1021/bi049510m  1
2004 Chang MC, Yee CS, Stubbe J, Nocera DG. Turning on ribonucleotide reductase by light-initiated amino acid radical generation. Proceedings of the National Academy of Sciences of the United States of America. 101: 6882-7. PMID 15123822 DOI: 10.1073/pnas.0401718101  1
2004 Chen J, Stubbe J. Synthesis and Characterization of Oligonucleotides Containing a 4′-Keto Abasic Site Biochemistry. 43: 5278-5286. PMID 15122893 DOI: 10.1021/bi0495376  1
2004 Chen J, Stubbe J. Bleomycins: New methods will allow reinvestigation of old issues Current Opinion in Chemical Biology. 8: 175-181. PMID 15062779 DOI: 10.1016/j.cbpa.2004.02.008  1
2003 Yee CS, Seyedsayamdost MR, Chang MC, Nocera DG, Stubbe J. Generation of the R2 subunit of ribonucleotide reductase by intein chemistry: insertion of 3-nitrotyrosine at residue 356 as a probe of the radical initiation process. Biochemistry. 42: 14541-52. PMID 14661967 DOI: 10.1021/bi0352365  1
2003 Bennati M, Weber A, Antonic J, Perlstein DL, Robblee J, Stubbe J. Pulsed ELDOR Spectroscopy Measures the Distance between the Two Tyrosyl Radicals in the R2 Subunit of the E. coli Ribonucleotide Reductase Journal of the American Chemical Society. 125: 14988-14989. PMID 14653724 DOI: 10.1021/ja0362095  1
2003 Stubbe J, Tian J. Polyhydroxyalkanoate (PHA) homeostasis: The role of the PHA synthase Natural Product Reports. 20: 445-457. PMID 14620841 DOI: 10.1039/b209687k  1
2003 Yee CS, Chang MC, Ge J, Nocera DG, Stubbe J. 2,3-difluorotyrosine at position 356 of ribonucleotide reductase R2: a probe of long-range proton-coupled electron transfer. Journal of the American Chemical Society. 125: 10506-7. PMID 12940718 DOI: 10.1021/ja036242r  1
2003 Ge J, Yu G, Ator MA, Stubbe J. Pre-steady-state and steady-state kinetic analysis of E. coli class I ribonucleotide reductase Biochemistry. 42: 10071-10083. PMID 12939135 DOI: 10.1021/bi034374r  1
2003 York GM, Lupberger J, Tian J, Lawrence AG, Stubbe J, Sinskey AJ. Ralstonia eutropha H16 encodes two and possibly three intracellular poly[D-(-)-3-hydroxybutyrate] depolymerase genes Journal of Bacteriology. 185: 3788-3794. PMID 12813072 DOI: 10.1128/JB.185.13.3788-3794.2003  1
2003 Stubbe J, Nocera DG, Yee CS, Chang MC. Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer? Chemical Reviews. 103: 2167-201. PMID 12797828 DOI: 10.1021/cr020421u  1
2003 Yao R, Zhang Z, An X, Bucci B, Perlstein DL, Stubbe J, Huang M. Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways Proceedings of the National Academy of Sciences of the United States of America. 100: 6628-6633. PMID 12732713 DOI: 10.1073/pnas.1131932100  1
2003 Stubbe J. Radicals with a controlled lifestyle Chemical Communications. 9: 2511-2513.  1
2002 Chang MC, Miller SE, Carpenter SD, Stubbe J, Nocera DG. Nanosecond generation of tyrosyl radicals via laser-initiated decaging of oxalate-modified amino acids. The Journal of Organic Chemistry. 67: 6820-2. PMID 12227817 DOI: 10.1021/jo025569s  1
1999 Licht SS, Lawrence CC, Stubbe J. Thermodynamic and kinetic studies on carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: the importance of entropy in catalysis. Biochemistry. 38: 1234-42. PMID 9930983 DOI: 10.1021/bi981886a  1
1999 Licht SS, Booker S, Stubbe J. Studies on the catalysis of carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: evidence for concerted carbon-cobalt bond homolysis and thiyl radical formation. Biochemistry. 38: 1221-33. PMID 9930982 DOI: 10.1021/bi981885i  1
1998 Stubbe J, van Der Donk WA. Protein Radicals in Enzyme Catalysis. [Chem. Rev. 1998, 98, 705minus sign762. Chemical Reviews. 98: 2661-2662. PMID 11848974  1
1998 Stubbe J, van Der Donk WA. Protein Radicals in Enzyme Catalysis. Chemical Reviews. 98: 705-762. PMID 11848913  1
1998 van der Donk WA, Yu G, Pérez L, Sanchez RJ, Stubbe J, Samano V, Robins MJ. Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphate. Biochemistry. 37: 6419-26. PMID 9572859 DOI: 10.1021/bi9729357  1
1996 van der Donk WA, Zeng C, Biemann K, Stubbe J, Hanlon A, Kyte J. Identification of an active site residue of the R1 subunit of ribonucleotide reductase from Escherichia coli: characterization of substrate-induced polypeptide cleavage by C225SR1. Biochemistry. 35: 10058-67. PMID 8756468 DOI: 10.1021/bi952869d  1
1996 van der Donk WA, Yu G, Silva DJ, Stubbe J, McCarthy JR, Jarvi ET, Matthews DP, Resvick RJ, Wagner E. Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitors. Biochemistry. 35: 8381-91. PMID 8679596 DOI: 10.1021/bi960190j  1
1995 Stubbe J, van der Donk WA. Ribonucleotide reductases: radical enzymes with suicidal tendencies. Chemistry & Biology. 2: 793-801. PMID 8807812  1
1972 Stubbe JA, Kenyon GL. Analogs of phosphoenolpyruvate. Substrate specificities of enolase and pyruvate kinase from rabbit muscle. Biochemistry. 11: 338-45. PMID 5062057  1
1971 Stubbe JA, Kenyon GL. Analogs of phosphoenolpyruvate. On the specificity of pyruvate kinase from rabbit muscle. Biochemistry. 10: 2669-77. PMID 5105182  1
Low-probability matches
2014 Tinning AR, Jensen BL, Schweda F, Machura K, Hansen PB, Stubbe J, Gramsbergen JB, Madsen K. The water channel aquaporin-1 contributes to renin cell recruitment during chronic stimulation of renin production. American Journal of Physiology. Renal Physiology. 307: F1215-26. PMID 25339696 DOI: 10.1152/ajprenal.00136.2014  0.16
2014 Eskildsen MP, Hansen PB, Stubbe J, Toft A, Walter S, Marcussen N, Rasmussen LM, Vanhoutte PM, Jensen BL. Prostaglandin I2 and prostaglandin E2 modulate human intrarenal artery contractility through prostaglandin E2-EP4, prostacyclin-IP, and thromboxane A2-TP receptors. Hypertension. 64: 551-6. PMID 24914192 DOI: 10.1161/HYPERTENSIONAHA.113.03051  0.16
2014 Isaksson GL, Stubbe J, Lyngs Hansen P, Jensen BL, Bie P. Salt sensitivity of renin secretion, glomerular filtration rate and blood pressure in conscious Sprague-Dawley rats. Acta Physiologica (Oxford, England). 210: 446-54. PMID 24188244 DOI: 10.1111/apha.12191  0.16
2013 Wang M, Jin W, Guo AM, Stubbe J. Cardiovascular inflammation. Mediators of Inflammation. 2013: 123513. PMID 23983400 DOI: 10.1155/2013/123513  0.16
2013 Øzbay LA, Stubbe J, Jespersen B, Jensen BL. The effects of calcineurin inhibitors on prostanoid synthesis: a randomized cross-over study in healthy humans. Transplant International : Official Journal of the European Society For Organ Transplantation. 26: 131-7. PMID 23190385 DOI: 10.1111/tri.12004  0.16
2013 Damkjær M, Isaksson GL, Stubbe J, Jensen BL, Assersen K, Bie P. Renal renin secretion as regulator of body fluid homeostasis. PflüGers Archiv : European Journal of Physiology. 465: 153-65. PMID 23096366 DOI: 10.1007/s00424-012-1171-2  0.16
2013 Friis UG, Madsen K, Stubbe J, Hansen PB, Svenningsen P, Bie P, Skøtt O, Jensen BL. Regulation of renin secretion by renal juxtaglomerular cells. PflüGers Archiv : European Journal of Physiology. 465: 25-37. PMID 22733355 DOI: 10.1007/s00424-012-1126-7  0.16
2012 Havelund T, Jensen BL, Vinholt PJ, Engvad B, Stubbe J. Ulcerating and stenosing enteropathy treated with misoprostol: a case report with analysis of prostaglandin metabolism. European Journal of Gastroenterology & Hepatology. 24: 1238-41. PMID 22786573 DOI: 10.1097/MEG.0b013e328356bc95  0.16
2012 Song WL, Stubbe J, Ricciotti E, Alamuddin N, Ibrahim S, Crichton I, Prempeh M, Lawson JA, Wilensky RL, Rasmussen LM, Puré E, FitzGerald GA. Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. The Journal of Clinical Investigation. 122: 1459-68. PMID 22406532 DOI: 10.1172/JCI59262  0.16
2010 Hui Y, Ricciotti E, Crichton I, Yu Z, Wang D, Stubbe J, Wang M, Puré E, FitzGerald GA. Targeted deletions of cyclooxygenase-2 and atherogenesis in mice. Circulation. 121: 2654-60. PMID 20530000 DOI: 10.1161/CIRCULATIONAHA.109.910687  0.16
2010 Yu Y, Stubbe J, Ibrahim S, Song WL, Smyth EM, Symth EM, Funk CD, FitzGerald GA. Cyclooxygenase-2-dependent prostacyclin formation and blood pressure homeostasis: targeted exchange of cyclooxygenase isoforms in mice. Circulation Research. 106: 337-45. PMID 19940265 DOI: 10.1161/CIRCRESAHA.109.204529  0.16
2009 Yu Y, Lucitt MB, Stubbe J, Cheng Y, Friis UG, Hansen PB, Jensen BL, Smyth EM, FitzGerald GA. Prostaglandin F2alpha elevates blood pressure and promotes atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 7985-90. PMID 19416858 DOI: 10.1073/pnas.0811834106  0.16
2009 Svenningsen P, Bistrup C, Friis UG, Bertog M, Haerteis S, Krueger B, Stubbe J, Jensen ON, Thiesson HC, Uhrenholt TR, Jespersen B, Jensen BL, Korbmacher C, Skøtt O. Plasmin in nephrotic urine activates the epithelial sodium channel. Journal of the American Society of Nephrology : Jasn. 20: 299-310. PMID 19073825 DOI: 10.1681/ASN.2008040364  0.16
2007 Stubbe J, Madsen K, Nielsen FT, Bonde RK, Skøtt O, Jensen BL. Postnatal adrenalectomy impairs urinary concentrating ability by increased COX-2 and leads to renal medullary injury American Journal of Physiology - Renal Physiology. 293: F780-F789. PMID 17581922 DOI: 10.1152/ajprenal.00193.2007  0.16
2006 Stubbe J, Madsen K, Nielsen FT, Skøtt O, Jensen BL. Glucocorticoid impairs growth of kidney outer medulla and accelerates loop of Henle differentiation and urinary concentrating capacity in rat kidney development American Journal of Physiology - Renal Physiology. 291: F812-F822. PMID 16638911 DOI: 10.1152/ajprenal.00477.2005  0.16
2005 Friis UG, Stubbe J, Uhrenholt TR, Svenningsen P, Nüsing RM, Skøtt O, Jensen BL. Prostaglandin E2 EP2 and EP4 receptor activation mediates cAMP-dependent hyperpolarization and exocytosis of renin in juxtaglomerular cells American Journal of Physiology - Renal Physiology. 289: F989-F997. PMID 15985651 DOI: 10.1152/ajprenal.00201.2005  0.16
2004 Jensen BL, Stubbe J, Madsen K, Nielsen FT, Skøtt O. The renin-angiotensin system in kidney development: Role of COX-2 and adrenal steroids Acta Physiologica Scandinavica. 181: 549-559. PMID 15283770 DOI: 10.1111/j.1365-201X.2004.01330.x  0.16
2004 Therland KL, Stubbe J, Thiesson HC, Ottosen PD, Walter S, Sørensen GL, Skøtt O, Jensen BL. Cycloxygenase-2 Is Expressed in Vasculature of Normal and Ischemic Adult Human Kidney and Is Colocalized with Vascular prostaglandin E2 EP4 Receptors Journal of the American Society of Nephrology. 15: 1189-1198. PMID 15100359 DOI: 10.1097/01.ASN.0000124673.79934.24  0.16
2004 Madsen K, Stubbe J, Yang T, Skøtt O, Bachmann S, Jensen BL. Low endogenous glucocorticoid allows induction of kidney cortical cyclooxygenase-2 during postnatal rat development American Journal of Physiology - Renal Physiology. 286: F26-F37. PMID 13129852  0.16
2003 Stubbe J, Jensen BL, Bachmann S, Morsing P, Skøtt O. Cyclooxygenase-2 contributes to elevated renin in the early postnatal period in rats American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 284: R1179-R1189. PMID 12560203  0.16
2015 Buckley RM, Stubbe J. Chemistry with an artificial primer of polyhydroxybutyrate synthase suggests a mechanism for chain termination. Biochemistry. 54: 2117-25. PMID 25741756 DOI: 10.1021/bi501405b  0.12
2015 van Beijsterveldt AM, Thijs KM, Backx FJ, Steffen K, Brozi?evi? V, Stubbe JH. Sports injuries and illnesses during the European Youth Olympic Festival 2013. British Journal of Sports Medicine. 49: 448-52. PMID 25573616 DOI: 10.1136/bjsports-2014-094035  0.04
2015 Stubbe JH, van Beijsterveldt AM, van der Knaap S, Stege J, Verhagen EA, van Mechelen W, Backx FJ. Injuries in professional male soccer players in the Netherlands: a prospective cohort study. Journal of Athletic Training. 50: 211-6. PMID 25531144 DOI: 10.4085/1062-6050-49.3.64  0.04
2015 van Beijsterveldt AM, Stubbe JH, Schmikli SL, van de Port IG, Backx FJ. Differences in injury risk and characteristics between Dutch amateur and professional soccer players. Journal of Science and Medicine in Sport / Sports Medicine Australia. 18: 145-9. PMID 24636127 DOI: 10.1016/j.jsams.2014.02.004  0.04
2014 van Beijsterveldt AM, Steffen K, Stubbe JH, Frederiks JE, van de Port IG, Backx FJ. Soccer injuries and recovery in Dutch male amateur soccer players: results of a prospective cohort study. Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine. 24: 337-42. PMID 24346734 DOI: 10.1097/JSM.0000000000000028  0.04
2014 Stubbe JH, Chorus AM, Frank LE, de Hon O, van der Heijden PG. Prevalence of use of performance enhancing drugs by fitness centre members. Drug Testing and Analysis. 6: 434-8. PMID 24019293 DOI: 10.1002/dta.1525  0.04
2013 Stege JP, Fleuren MAH, Van Der Knaap ETW, Stubbe JH. Digital Sport Medical Record: Sigh or a blessing? | Het digitale sport medisch dossier: Zucht of zegen? Sport En Geneeskunde. 46: 16-23.  0.04
2012 van Beijsterveldt AM, van de Port IG, Krist MR, Schmikli SL, Stubbe JH, Frederiks JE, Backx FJ. Effectiveness of an injury prevention programme for adult male amateur soccer players: a cluster-randomised controlled trial. British Journal of Sports Medicine. 46: 1114-8. PMID 22878257 DOI: 10.1136/bjsports-2012-091277  0.04
2011 Vink JM, Boomsma DI, Medland SE, de Moor MH, Stubbe JH, Cornes BK, Martin NG, Skytthea A, Kyvik KO, Rose RJ, Kujala UM, Kaprio J, Harris JR, Pedersen NL, Cherkas L, et al. Variance components models for physical activity with age as modifier: a comparative twin study in seven countries. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 14: 25-34. PMID 21314253 DOI: 10.1375/twin.14.1.25  0.04
2011 van Beijsterveldt AM, Krist MR, Schmikli SL, Stubbe JH, de Wit GA, Inklaar H, van de Port IG, Backx FJ. Effectiveness and cost-effectiveness of an injury prevention programme for adult male amateur soccer players: design of a cluster-randomised controlled trial. Injury Prevention : Journal of the International Society For Child and Adolescent Injury Prevention. 17: e2. PMID 21177664 DOI: 10.1136/ip.2010.027979  0.04
2011 De Moor MH, Willemsen G, Rebollo-Mesa I, Stubbe JH, De Geus EJ, Boomsma DI. Exercise participation in adolescents and their parents: evidence for genetic and generation specific environmental effects. Behavior Genetics. 41: 211-22. PMID 21086156 DOI: 10.1007/s10519-010-9415-4  0.04
2011 Prins JC, Stubbe JH, van Meeteren NL, Scheffers FA, van Dongen MC. Feasibility and preliminary effectiveness of ice therapy in patients with an acute tear in the gastrocnemius muscle: a pilot randomized controlled trial. Clinical Rehabilitation. 25: 433-41. PMID 21059665 DOI: 10.1177/0269215510388312  0.04
2010 De Geus EJC, Stubbe JH. Aerobic Exercise and Stress Reduction Encyclopedia of Stress. 73-78. DOI: 10.1016/B978-012373947-6.00014-3  0.04
2009 Damman OC, Stubbe JH, Hendriks M, Arah OA, Spreeuwenberg P, Delnoij DM, Groenewegen PP. Using multilevel modeling to assess case-mix adjusters in consumer experience surveys in health care. Medical Care. 47: 496-503. PMID 19238105 DOI: 10.1097/MLR.0b013e31818afa05  0.04
2009 Stubbe JH, De Geus EJC. Genetics of exercise behavior Handbook of Behavior Genetics. 343-358. DOI: 10.1007/978-0-387-76727-7_24  0.04
2008 De Moor MH, Boomsma DI, Stubbe JH, Willemsen G, de Geus EJ. Testing causality in the association between regular exercise and symptoms of anxiety and depression. Archives of General Psychiatry. 65: 897-905. PMID 18678794 DOI: 10.1001/archpsyc.65.8.897  0.04
2007 Stubbe JH, Brouwer W, Delnoij DMJ. Patients' experiences with quality of hospital care: The Consumer Quality Index Cataract Questionnaire Bmc Ophthalmology. 7. PMID 17877840 DOI: 10.1186/1471-2415-7-14  0.04
2007 Stubbe JH, Gelsema T, Delnoij DMJ. The Consumer Quality Index Hip Knee Questionnaire measuring patients' experiences with quality of care after a total hip or knee arthroplasty Bmc Health Services Research. 7. PMID 17462084 DOI: 10.1186/1472-6963-7-60  0.04
2007 De Moor MHM, Stubbe JH, Boomsma DI, De Geus EJC. Exercise participation and self-rated health: Do common genes explain the association? European Journal of Epidemiology. 22: 27-32. PMID 17195050 DOI: 10.1007/s10654-006-9088-8  0.04
2007 Stubbe JH, de Moor MHM, Boomsma DI, de Geus EJC. The association between exercise participation and well-being: A co-twin study Preventive Medicine. 44: 148-152. PMID 17059845 DOI: 10.1016/j.ypmed.2006.09.002  0.04
2006 Boomsma DI, de Geus EJ, Vink JM, Stubbe JH, Distel MA, Hottenga JJ, Posthuma D, van Beijsterveldt TC, Hudziak JJ, Bartels M, Willemsen G. Netherlands Twin Register: from twins to twin families. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 9: 849-57. PMID 17254420 DOI: 10.1375/183242706779462426  0.04
2006 Stubbe JH, Boomsma DI, Vink JM, Cornes BK, Martin NG, Skytthe A, Kyvik KO, Rose RJ, Kujala UM, Kaprio J, Harris JR, Pedersen NL, Hunkin J, Spector TD, de Geus EJC. Genetic influences on exercise participation in 37.051 twin pairs from seven countries Plos One. 1. PMID 17183649 DOI: 10.1371/journal.pone.0000022  0.04
2006 Hillman CH, Motl RW, Pontifex MB, Posthuma D, Stubbe JH, Boomsma DI, de Geus EJ. Physical activity and cognitive function in a cross-section of younger and older community-dwelling individuals. Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association. 25: 678-87. PMID 17100496 DOI: 10.1037/0278-6133.25.6.678  0.04
2006 Ligthart L, Boomsma DI, Martin NG, Stubbe JH, Nyholt DR. Migraine with aura and migraine without aura are not distinct entities: Further evidence from a large Dutch population study Twin Research and Human Genetics. 9: 54-63. PMID 16611468 DOI: 10.1375/183242706776403019  0.04
2006 De Moor MHM, Beem AL, Stubbe JH, Boomsma DI, De Geus EJC. Regular exercise, anxiety, depression and personality: A population-based study Preventive Medicine. 42: 273-279. PMID 16439008 DOI: 10.1016/j.ypmed.2005.12.002  0.04
2006 Stubbe J. The genetics of exercise behavior and psychological well-being | De erfelijkheid van sportgedrag en psychologisch welbevinden Geneeskunde En Sport. 39: 201-202.  0.04
2005 Stubbe JH, Posthuma D, Boomsma DI, De Geus EJ. Heritability of life satisfaction in adults: a twin-family study. Psychological Medicine. 35: 1581-8. PMID 16219116 DOI: 10.1017/S0033291705005374  0.04
2005 Middeldorp CM, Stubbe JH, Cath DC, Boomsma DI. Familial clustering in burnout: A twin-family study Psychological Medicine. 35: 113-120. PMID 15842034 DOI: 10.1017/S0033291704002983  0.04
2005 Stubbe JH, Boomsma DI, De Geus EJC. Sports participation during adolescence: A shift from environmental to genetic factors Medicine and Science in Sports and Exercise. 37: 563-570. PMID 15809553 DOI: 10.1249/01.MSS.0000158181.75442.8B  0.04
2004 Vink JM, Willemsen G, Stubbe JH, Middeldorp CM, Ligthart RSL, Baas KD, Dirkzwager HJC, De Geus EJC, Boomsma DI. Estimating non-response bias in family studies: Application to mental health and lifestyle European Journal of Epidemiology. 19: 623-630. DOI: 10.1023/B:EJEP.0000036814.56108.66  0.04
2003 Sawicki PT, Gläser B, Kleespies C, Stubbe J, Schmitz N, Kaiser T, Didjurgeit U. Self-management of oral anticoagulation: Long-term results [2] Journal of Internal Medicine. 254: 515-516. PMID 14535976 DOI: 10.1046/j.1365-2796.2003.01215.x  0.04
2003 Sawicki PT, Gläser B, Kleespies C, Stubbe J, Schmitz N, Kaiser T, Didjurgeit U. Long-Term Results of Patients' Self-Management of Oral Anticoagulation Journal of Clinical and Basic Cardiology. 6: 59-62.  0.04
2015 Schlosser A, Pilecki B, Hemstra LE, Kejling K, Kristmannsdottir GB, Wulf-Johansson H, Moeller JB, Füchtbauer EM, Nielsen O, Kirketerp-Møller K, Dubey LK, Hansen PB, Stubbe J, Wrede C, Hegermann J, et al. MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26564819 DOI: 10.1161/ATVBAHA.115.306672  0.01
2015 Tak I, Weir A, Langhout R, Waarsing JH, Stubbe J, Kerkhoffs G, Agricola R. The relationship between the frequency of football practice during skeletal growth and the presence of a cam deformity in adult elite football players. British Journal of Sports Medicine. 49: 630-4. PMID 25568331 DOI: 10.1136/bjsports-2014-094130  0.01
2015 Stubbe J. Comparative heuristics from an STS perspective. Inquiring "Novelty" in material practice Historical Social Research. 40: 109-129. DOI: 10.12759/hsr.40.2015.3.109-129  0.01
2014 De Bruycker E, De Vroey S, Huysmans S, Stubbe J. Phenomenology of hydrogen flaking in nuclear reactor pressure vessels Materialpruefung/Materials Testing. 56: 439-444. DOI: 10.3139/120.110580  0.01
2014 Harrell EM, Stubbe J. On sums of graph eigenvalues Linear Algebra and Its Applications. 455: 168-186. DOI: 10.1016/j.laa.2014.05.001  0.01
2011 Harrell EM, Stubbe J. Trace identities for commutators, with applications to the distribution of eigenvalues Transactions of the American Mathematical Society. 363: 6385-6405. DOI: 10.1090/S0002-9947-2011-05252-9  0.01
2010 Stubbe J. Universal monotonicity of eigenvalue moments and sharp Lieb-Thirring inequalities Journal of the European Mathematical Society. 12: 1347-1353. DOI: 10.4171/JEMS/233  0.01
2010 Harrell EM, Stubbe J. Universal bounds and semiclassical estimates for eigenvalues of abstract Schrödinger operators Siam Journal On Mathematical Analysis. 42: 2261-2274. DOI: 10.1137/090763743  0.01
2010 Stubbe J, Vuffray M. Bound states of the Schrödinger-Newton model in low dimensions Nonlinear Analysis, Theory, Methods and Applications. 73: 3171-3178. DOI: 10.1016/j.na.2010.06.072  0.01
2009 Stubbe JW, Fockens P. Endoscopic Ultrasonography and Colonoscopy Colonoscopy: Principles and Practice, Second Edition. 501-513. DOI: 10.1002/9781444316902.ch37  0.01
2007 Choquard P, Stubbe J. The one-dimensional Schrödinger-Newton equations Letters in Mathematical Physics. 81: 177-184. DOI: 10.1007/s11005-007-0174-y  0.01
2007 Biollay Y, Chaabouni A, Stubbe J. Math part!: Basics and exercises for the first year of Engineering | Matematica si parte!:Nozioni di base ed esercizi per il primo anno di Ingegneria Unitext - La Matematica Per Il 3 Piu 2. 33.  0.01
2006 Stubbe J. EURELECTRIC'S view on R&D needs Vgb Powertech. 86: 30-33+6.  0.01
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