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Eric N. Jacobsen - Publications

Affiliations: 
Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
Mechanistic and synthetic chemistry
Website:
http://www.chem.harvard.edu/groups/Jacobsen/
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289 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Blackburn MAS, Wagen CC, Bodrogean MR, Tadross PM, Bendelsmith AJ, Kutateladze DA, Jacobsen EN. Dual-Hydrogen-Bond Donor and Brønsted Acid Cocatalysis Enables Highly Enantioselective Protio-Semipinacol Rearrangement Reactions. Journal of the American Chemical Society. PMID 37428959 DOI: 10.1021/jacs.3c02960  0.839
2023 Ovian JM, Vojáčková P, Jacobsen EN. Enantioselective Transition-Metal Catalysis via an Anion-Binding Approach. Nature. PMID 36787801 DOI: 10.1038/s41586-023-05804-3  0.824
2022 Samha MH, Wahlman JLH, Read JA, Werth J, Jacobsen EN, Sigman MS. Exploring Structure-Function Relationships of Aryl Pyrrolidine-Based Hydrogen-Bond Donors in Asymmetric Catalysis Using Data-Driven Techniques. Acs Catalysis. 12: 14836-14845. PMID 36816226 DOI: 10.1021/acscatal.2c04824  0.614
2022 Wagen CC, Jacobsen EN. Evidence for Oxonium Ions in Ethereal "Hydrogen Chloride". Organic Letters. PMID 36450043 DOI: 10.1021/acs.orglett.2c03622  0.799
2022 Wagen CC, McMinn SE, Kwan EE, Jacobsen EN. Screening for Generality in Asymmetric Catalysis. Nature. PMID 36049504 DOI: 10.1038/s41586-022-05263-2  0.838
2022 Kutateladze DA, Wagen CC, Jacobsen EN. Chloride-Mediated Alkene Activation Drives Enantioselective Thiourea and Hydrogen Chloride Co-Catalyzed Prins Cyclizations. Journal of the American Chemical Society. PMID 35994741 DOI: 10.1021/jacs.2c06688  0.843
2022 Li Q, Levi SM, Wagen C, Wendlandt AE, Jacobsen EN. Site-selective, stereocontrolled glycosylation of minimally protected sugars. Nature. PMID 35709829 DOI: 10.1038/s41586-022-04958-w  0.816
2021 Kutateladze DA, Jacobsen EN. Cooperative Hydrogen-Bond-Donor Catalysis with Hydrogen Chloride Enables Highly Enantioselective Prins Cyclization Reactions. Journal of the American Chemical Society. PMID 34812618 DOI: 10.1021/jacs.1c10890  0.434
2021 Sharma HA, Essman JZ, Jacobsen EN. Enantioselective catalytic 1,2-boronate rearrangements. Science (New York, N.Y.). 374: 752-757. PMID 34735250 DOI: 10.1126/science.abm0386  0.843
2021 Strassfeld DA, Algera RF, Wickens ZK, Jacobsen EN. A Case Study in Catalyst Generality: Simultaneous, Highly-Enantioselective Brønsted- and Lewis-Acid Mechanisms in Hydrogen-Bond-Donor Catalyzed Oxetane Openings. Journal of the American Chemical Society. PMID 34152759 DOI: 10.1021/jacs.1c03992  0.463
2021 Ronchi E, Paradine SM, Jacobsen EN. Enantioselective, Catalytic Multicomponent Synthesis of Homoallylic Amines Enabled by Hydrogen-Bonding and Dispersive Interactions. Journal of the American Chemical Society. PMID 33949857 DOI: 10.1021/jacs.1c03024  0.848
2020 Metternich JB, Reiterer M, Jacobsen EN. Asymmetric Nazarov Cyclizations of Unactivated Dienones by Hydrogen-Bond-Donor/Lewis Acid Co-Catalyzed, Enantioselective Proton-Transfer. Advanced Synthesis & Catalysis. 362: 4092-4097. PMID 33162875 DOI: 10.1002/Adsc.202000831  0.434
2020 Kennedy CR, Choi BY, Reeves MR, Jacobsen EN. Enantioselective Catalysis of an Anionic Oxy-Cope Rearrangement Enabled by Synergistic Ion Binding. Israel Journal of Chemistry. 60: 461-474. PMID 33132416 DOI: 10.1002/Ijch.201900168  0.44
2020 Sharma H, Mennie KM, Kwan EE, Jacobsen EN. Enantioselective Aryl-Iodide-Catalyzed Wagner-Meerwein Rearrangements. Journal of the American Chemical Society. PMID 32845619 DOI: 10.1021/Jacs.0C08150  0.763
2020 Levin MD, Ovian JM, Read JA, Sigman MS, Jacobsen EN. Catalytic Enantioselective Synthesis of Difluorinated Alkyl Bromides. Journal of the American Chemical Society. PMID 32799536 DOI: 10.1021/Jacs.0C07043  0.852
2020 Li Q, Levi SM, Jacobsen EN. Highly Selective β-Mannosylations and β-Rhamnosylations Catalyzed by Bis-thiourea. Journal of the American Chemical Society. PMID 32527078 DOI: 10.1021/Jacs.0C04255  0.328
2020 Strassfeld DA, Wickens ZK, Picazo E, Jacobsen EN. Highly Enantioselective, Hydrogen-Bond-Donor Catalyzed Additions to Oxetanes. Journal of the American Chemical Society. PMID 32364378 DOI: 10.1021/Jacs.0C03991  0.857
2020 Kutateladze DA, Strassfeld DA, Jacobsen EN. Enantioselective Tail-to-Head Cyclizations Catalyzed by Dual-Hydrogen-Bond Donors. Journal of the American Chemical Society. PMID 32223127 DOI: 10.1021/Jacs.0C02665  0.543
2020 Mayfield AB, Metternich JB, Trotta AH, Jacobsen EN. Stereospecific Furanosylations Catalyzed by Bis-Thiourea Hydrogen-Bond Donors. Journal of the American Chemical Society. PMID 32013410 DOI: 10.1021/Jacs.0C00335  0.504
2019 Ovian JM, Jacobsen EN. A catalytic one-two punch. Science (New York, N.Y.). 366: 948-949. PMID 31753983 DOI: 10.1126/Science.Aaz6166  0.835
2019 Bendelsmith AJ, Kim SC, Wasa M, Roche SP, Jacobsen EN. Enantioselective Synthesis of α-Allyl Amino Esters via Hydrogen-Bond Donor Catalysis. Journal of the American Chemical Society. PMID 31280564 DOI: 10.1021/Jacs.9B05556  0.707
2019 Haj MK, Banik SM, Jacobsen EN. Catalytic, Enantioselective 1,2-Difluorination of Cinnamamides. Organic Letters. PMID 30963766 DOI: 10.1021/Acs.Orglett.9B00938  0.826
2019 Levi SM, Li Q, Rötheli AR, Jacobsen EN. Catalytic activation of glycosyl phosphates for stereoselective coupling reactions. Proceedings of the National Academy of Sciences of the United States of America. 116: 35-39. PMID 30559190 DOI: 10.1073/Pnas.1811186116  0.483
2018 Zhou B, Haj MK, Jacobsen EN, Houk KN, Xue XS. Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes. Journal of the American Chemical Society. PMID 30350956 DOI: 10.1021/Jacs.8B05935  0.461
2018 Kwan EE, Zeng Y, Besser HA, Jacobsen EN. Concerted nucleophilic aromatic substitutions. Nature Chemistry. PMID 30013193 DOI: 10.1038/S41557-018-0079-7  0.66
2018 Wendlandt AE, Vangal P, Jacobsen EN. Quaternary stereocentres via an enantioconvergent catalytic S1 reaction. Nature. 556: 447-451. PMID 29695848 DOI: 10.1038/S41586-018-0042-1  0.823
2018 Mennie KM, Banik SM, Reichert EC, Jacobsen EN. Catalytic Diastereo- and Enantioselective Fluoroamination of Alkenes. Journal of the American Chemical Society. PMID 29583001 DOI: 10.1021/Jacs.8B02143  0.836
2017 Banik SM, Levina A, Hyde AM, Jacobsen EN. Lewis acid enhancement by hydrogen-bond donors for asymmetric catalysis. Science (New York, N.Y.). 358: 761-764. PMID 29123063 DOI: 10.1126/Science.Aao5894  0.825
2017 Klausen RS, Kennedy CR, Hyde AM, Jacobsen EN. Chiral Thioureas Promote Enantioselective Pictet-Spengler Cyclization by Stabilizing Every Intermediate and Transition State in the Carboxylic Acid-Catalyzed Reaction. Journal of the American Chemical Society. PMID 28787140 DOI: 10.1021/Jacs.7B06811  0.777
2017 Banik SM, Mennie K, Jacobsen EN. Catalytic 1,3-Difunctionalization via Oxidative C-C Bond Activation. Journal of the American Chemical Society. PMID 28622723 DOI: 10.1021/Jacs.7B05160  0.785
2017 Park Y, Harper KC, Kuhl N, Kwan EE, Liu RY, Jacobsen EN. Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions. Science (New York, N.Y.). 355: 162-166. PMID 28082586 DOI: 10.1126/Science.Aal1875  0.824
2017 List B, Shevchenko GA, Park Y, Harper KC, Kuhl N, Kwan EE, Liu RY, Jacobsen EN. Stereospecific Glycosylation through Catalytic Stereoinversion Synfacts. 13: 420. DOI: 10.1055/S-0036-1590092  0.482
2016 Ford DD, Lehnherr D, Kennedy CR, Jacobsen EN. Anion-Abstraction Catalysis: The Cooperative Mechanism of α-Chloroether Activation by Dual Hydrogen-Bond Donors. Acs Catalysis. 6: 4616-4620. PMID 31754547 DOI: 10.1021/Acscatal.6B01384  0.849
2016 Kwan EE, Park Y, Besser HA, Anderson TL, Jacobsen EN. Sensitive and Accurate 13C Kinetic Isotope Effect Measurements Enabled by Polarization Transfer. Journal of the American Chemical Society. PMID 28005341 DOI: 10.1021/Jacs.6B10621  0.301
2016 Park Y, Schindler CS, Jacobsen EN. Enantioselective Aza-Sakurai Cyclizations: Dual Role of Thiourea as H-bond Donor and Lewis Base. Journal of the American Chemical Society. PMID 27787993 DOI: 10.1021/Jacs.6B09736  0.703
2016 Woerly E, Banik SM, Jacobsen EN. Enantioselective, Catalytic Fluorolactonization Reactions with a Nucleophilic Fluoride Source. Journal of the American Chemical Society. PMID 27709922 DOI: 10.1021/Jacs.6B09499  0.856
2016 Kennedy CR, Lehnherr D, Rajapaksa NS, Ford DD, Park Y, Jacobsen EN. Mechanism-Guided Development of a Highly Active Bis-Thiourea Catalyst for Anion-Abstraction Catalysis. Journal of the American Chemical Society. 138: 13525–8. PMID 27704810 DOI: 10.1021/Jacs.6B09205  0.84
2016 Hennessy ET, Jacobsen EN. Organometallic chemistry: A new metathesis. Nature Chemistry. 8: 741-742. PMID 27442278 DOI: 10.1038/Nchem.2581  0.457
2016 Kennedy CR, Guidera JA, Jacobsen EN. Synergistic Ion-Binding Catalysis Demonstrated via an Enantioselective, Catalytic [2,3]-Wittig Rearrangement. Acs Central Science. 2: 416-23. PMID 27413786 DOI: 10.1021/Acscentsci.6B00125  0.531
2016 Banik SM, Medley JW, Jacobsen EN. Catalytic, asymmetric difluorination of alkenes to generate difluoromethylated stereocenters. Science (New York, N.Y.). 353: 51-4. PMID 27365443 DOI: 10.1126/Science.Aaf8078  0.828
2016 Kennedy CR, Lin S, Jacobsen EN. The Cation-π Interaction in Small-Molecule Catalysis. Angewandte Chemie (International Ed. in English). PMID 27329991 DOI: 10.1002/Anie.201600547  0.55
2016 Lehnherr D, Ford DD, Bendelsmith AJ, Kennedy CR, Jacobsen EN. Conformational Control of Chiral Amido-Thiourea Catalysts Enables Improved Activity and Enantioselectivity. Organic Letters. 18: 3214-7. PMID 27294369 DOI: 10.1021/Acs.Orglett.6B01435  0.855
2016 Ford DD, Lehnherr D, Kennedy CR, Jacobsen EN. On- and Off-Cycle Catalyst Cooperativity in Anion-Binding Catalysis. Journal of the American Chemical Society. 138: 7860-3. PMID 27276389 DOI: 10.1021/Jacs.6B04686  0.855
2016 Banik SM, Medley JW, Jacobsen EN. Catalytic, Diastereoselective 1,2-Difluorination of Alkenes. Journal of the American Chemical Society. PMID 27046019 DOI: 10.1021/Jacs.6B02391  0.828
2016 Ford DD, Lehnherr D, Kennedy CR, Jacobsen EN. Anion-Abstraction Catalysis: The Cooperative Mechanism of α-Chloroether Activation by Dual H-Bond Donors Acs Catalysis. 6: 4616–4620. DOI: 10.1021/acscatal.6b01384  0.761
2016 Kennedy CR, Lin S, Jacobsen EN. Die Kation-π-Wechselwirkung in der Katalyse mit niedermolekularen Verbindungen Angewandte Chemie. 128: 12784-12814. DOI: 10.1002/Ange.201600547  0.45
2016 Jacobsen EN. Advanced Synthesis & Catalysis after 15 Years: Challenges and New Opportunities for Synthetic Science Advanced Synthesis and Catalysis. 358: 2. DOI: 10.1002/Adsc.201600013  0.323
2015 Turek AK, Hardee DJ, Ullman AM, Nocera DG, Jacobsen EN. Activation of Electron-Deficient Quinones through Hydrogen-Bond-Donor-Coupled Electron Transfer. Angewandte Chemie (International Ed. in English). PMID 26612607 DOI: 10.1002/Anie.201508060  0.312
2015 Liu RY, Wasa M, Jacobsen EN. Enantioselective synthesis of tertiary α-chloro esters by non-covalent catalysis. Tetrahedron Letters. 56: 3428-3430. PMID 26085694 DOI: 10.1016/J.Tetlet.2015.01.124  0.751
2015 Witten MR, Jacobsen EN. A Simple Primary Amine Catalyst for Enantioselective α-Hydroxylations and α-Fluorinations of Branched Aldehydes. Organic Letters. 17: 2772-5. PMID 25952578 DOI: 10.1021/Acs.Orglett.5B01193  0.689
2014 Fang YQ, Tadross PM, Jacobsen EN. Highly enantioselective, intermolecular hydroamination of allenyl esters catalyzed by bifunctional phosphinothioureas. Journal of the American Chemical Society. 136: 17966-8. PMID 25496451 DOI: 10.1021/Ja5117638  0.483
2014 Zhang H, Lin S, Jacobsen EN. Enantioselective selenocyclization via dynamic kinetic resolution of seleniranium ions by hydrogen-bond donor catalysts. Journal of the American Chemical Society. 136: 16485-8. PMID 25380129 DOI: 10.1021/Ja510113S  0.66
2014 Yeung CS, Ziegler RE, Porco JA, Jacobsen EN. Thiourea-catalyzed enantioselective addition of indoles to pyrones: alkaloid cores with quaternary carbons. Journal of the American Chemical Society. 136: 13614-7. PMID 25213353 DOI: 10.1021/Ja508523G  0.522
2014 Wasa M, Liu RY, Roche SP, Jacobsen EN. Asymmetric Mannich synthesis of α-amino esters by anion-binding catalysis. Journal of the American Chemical Society. 136: 12872-5. PMID 25178040 DOI: 10.1021/Ja5075163  0.728
2014 White DE, Tadross PM, Lu Z, Jacobsen EN. A broadly applicable and practical oligomeric (salen) Co catalyst for enantioselective epoxide ring-opening reactions. Tetrahedron. 70: 4165-4180. PMID 25045188 DOI: 10.1016/J.Tet.2014.03.043  0.767
2014 Xu H, Zhang H, Jacobsen EN. Chiral sulfinamidourea and strong Brønsted acid-cocatalyzed enantioselective Povarov reaction to access tetrahydroquinolines. Nature Protocols. 9: 1860-6. PMID 25010906 DOI: 10.1038/Nprot.2014.125  0.637
2014 Witten MR, Jacobsen EN. Catalytic asymmetric synthesis of 8-oxabicyclooctanes by intermolecular [5+2] pyrylium cycloadditions. Angewandte Chemie (International Ed. in English). 53: 5912-6. PMID 24782332 DOI: 10.1002/Anie.201402834  0.726
2014 Bergonzini G, Schindler CS, Wallentin CJ, Jacobsen EN, Stephenson CR. Photoredox Activation and Anion Binding Catalysis in the Dual Catalytic Enantioselective Synthesis of β-Amino Esters. Chemical Science (Royal Society of Chemistry : 2010). 5. PMID 24294480 DOI: 10.1039/C3Sc52265B  0.632
2014 Witten MR, Jacobsen EN. Catalytic Asymmetric Synthesis of 8-Oxabicyclooctanes Synfacts. 10: 753-753. DOI: 10.1055/S-0034-1378223  0.537
2013 Brindle CS, Yeung CS, Jacobsen EN. Chiral β-Iodoamines by Urea-Catalyzed Iodocyclization of Trichloroacetimidates. Chemical Sciences Journal. 4. PMID 24416631 DOI: 10.1039/C3Sc50410G  0.823
2013 Ford DD, Nielsen LP, Zuend SJ, Musgrave CB, Jacobsen EN. Mechanistic basis for high stereoselectivity and broad substrate scope in the (salen)Co(III)-catalyzed hydrolytic kinetic resolution. Journal of the American Chemical Society. 135: 15595-608. PMID 24041239 DOI: 10.1021/Ja408027P  0.817
2013 Rajapaksa NS, Jacobsen EN. Enantioselective catalytic transannular ketone-ene reactions. Organic Letters. 15: 4238-41. PMID 23923982 DOI: 10.1021/Ol401968M  0.851
2013 Birrell JA, Jacobsen EN. A practical method for the synthesis of highly enantioenriched trans-1,2-amino alcohols. Organic Letters. 15: 2895-7. PMID 23742206 DOI: 10.1021/Ol401013S  0.65
2013 Schindler CS, Jacobsen EN. Chemistry. A new twist on cooperative catalysis. Science (New York, N.Y.). 340: 1052-3. PMID 23723222 DOI: 10.1126/Science.1238769  0.705
2013 Brown AR, Uyeda C, Brotherton CA, Jacobsen EN. Enantioselective thiourea-catalyzed intramolecular cope-type hydroamination. Journal of the American Chemical Society. 135: 6747-9. PMID 23597402 DOI: 10.1021/Ja402893Z  0.801
2013 Rajapaksa NS, McGowan MA, Rienzo M, Jacobsen EN. Enantioselective total synthesis of (+)-reserpine. Organic Letters. 15: 706-9. PMID 23331099 DOI: 10.1021/Ol400046N  0.866
2013 Lalonde MP, McGowan MA, Rajapaksa NS, Jacobsen EN. Enantioselective formal aza-Diels-Alder reactions of enones with cyclic imines catalyzed by primary aminothioureas. Journal of the American Chemical Society. 135: 1891-4. PMID 23321009 DOI: 10.1021/Ja310718F  0.834
2013 Brak K, Jacobsen EN. Asymmetric ion-pairing catalysis. Angewandte Chemie (International Ed. in English). 52: 534-61. PMID 23192886 DOI: 10.1002/Anie.201205449  0.813
2013 Gerard B, O’Shea MW, Donckele E, Kesavan S, Akella LB, Xu H, Jacobsen EN, Marcaurelle LA. Correction to Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahydroquinoline Library Acs Combinatorial Science. 16: 46-46. DOI: 10.1021/Co400123X  0.619
2012 Tadross PM, Jacobsen EN. Site-selective reactions: Remodelling by diversity and design. Nature Chemistry. 4: 963-5. PMID 23174971 DOI: 10.1038/Nchem.1509  0.341
2012 Gerard B, O'Shea MW, Donckele E, Kesavan S, Akella LB, Xu H, Jacobsen EN, Marcaurelle LA. Application of a catalytic asymmetric Povarov reaction using chiral ureas to the synthesis of a tetrahydroquinoline library. Acs Combinatorial Science. 14: 621-30. PMID 23088641 DOI: 10.1021/Co300098V  0.547
2012 Lin S, Jacobsen EN. Thiourea-catalysed ring opening of episulfonium ions with indole derivatives by means of stabilizing non-covalent interactions. Nature Chemistry. 4: 817-24. PMID 23000995 DOI: 10.1038/Nchem.1450  0.659
2012 Burns NZ, Jacobsen EN. Organic chemistry: catalysis in tight spaces. Nature. 483: 278-9. PMID 22422255 DOI: 10.1038/483278A  0.745
2012 Nielsen LP, Zuend SJ, Ford DD, Jacobsen EN. Mechanistic basis for high reactivity of (salen)Co-OTs in the hydrolytic kinetic resolution of terminal epoxides. The Journal of Organic Chemistry. 77: 2486-95. PMID 22292515 DOI: 10.1021/Jo300181F  0.854
2011 Lee Y, Klausen RS, Jacobsen EN. Thiourea-catalyzed enantioselective iso-Pictet-Spengler reactions. Organic Letters. 13: 5564-7. PMID 21919478 DOI: 10.1021/Ol202300T  0.855
2011 Burns NZ, Witten MR, Jacobsen EN. Dual catalysis in enantioselective oxidopyrylium-based [5 + 2] cycloadditions. Journal of the American Chemical Society. 133: 14578-81. PMID 21848300 DOI: 10.1021/Ja206997E  0.83
2011 Birrell JA, Desrosiers JN, Jacobsen EN. Enantioselective acylation of silyl ketene acetals through fluoride anion-binding catalysis. Journal of the American Chemical Society. 133: 13872-5. PMID 21800916 DOI: 10.1021/Ja205602J  0.766
2011 Beck EM, Hyde AM, Jacobsen EN. Chiral sulfinamide/achiral sulfonic acid cocatalyzed enantioselective protonation of enol silanes. Organic Letters. 13: 4260-3. PMID 21786775 DOI: 10.1021/Ol201608A  0.697
2011 Uyeda C, Jacobsen EN. Transition-state charge stabilization through multiple non-covalent interactions in the guanidinium-catalyzed enantioselective Claisen rearrangement. Journal of the American Chemical Society. 133: 5062-75. PMID 21391614 DOI: 10.1021/Ja110842S  0.774
2011 Burns NZ, Witten MR, Jacobsen EN. Thiourea-Catalyzed Intramolecular [5+2] Cycloadditions Synfacts. 2011: 1241-1241. DOI: 10.1055/S-0031-1289260  0.783
2011 Beck EM, Hyde AM, Jacobsen EN. Enantioselective Protonation of Enol Silanes by ProtonatedChiral Sulfinamides Synfacts. 2011: 1131-1131. DOI: 10.1055/S-0030-1261120  0.395
2011 Jacobsen E, Uyeda C, Rötheli A. Chiral Guanidinium-Catalyzed Enantioselective Claisen Rearrangement Synfacts. 2011: 0215-0215. DOI: 10.1055/S-0030-1259348  0.518
2010 Jacobsen EN, MacMillan DW. Organocatalysis. Proceedings of the National Academy of Sciences of the United States of America. 107: 20618-9. PMID 21119011 DOI: 10.1073/Pnas.1016087107  0.667
2010 Uyeda C, Rötheli AR, Jacobsen EN. Catalytic enantioselective claisen rearrangements of O-allyl β-ketoesters. Angewandte Chemie (International Ed. in English). 49: 9753-6. PMID 21080393 DOI: 10.1002/Anie.201005183  0.743
2010 Knowles RR, Jacobsen EN. Attractive noncovalent interactions in asymmetric catalysis: links between enzymes and small molecule catalysts. Proceedings of the National Academy of Sciences of the United States of America. 107: 20678-85. PMID 20956302 DOI: 10.1073/Pnas.1006402107  0.692
2010 Veitch GE, Jacobsen EN. Tertiary aminourea-catalyzed enantioselective iodolactonization. Angewandte Chemie (International Ed. in English). 49: 7332-5. PMID 20803601 DOI: 10.1002/Anie.201003681  0.509
2010 McGowan MA, Stevenson CP, Schiffler MA, Jacobsen EN. An enantioselective total synthesis of (+)-peloruside A. Angewandte Chemie (International Ed. in English). 49: 6147-50. PMID 20586089 DOI: 10.1002/Anie.201002177  0.846
2010 Brown AR, Kuo WH, Jacobsen EN. Enantioselective catalytic alpha-alkylation of aldehydes via an SN1 pathway. Journal of the American Chemical Society. 132: 9286-8. PMID 20568761 DOI: 10.1021/Ja103618R  0.625
2010 Knowles RR, Lin S, Jacobsen EN. Enantioselective thiourea-catalyzed cationic polycyclizations. Journal of the American Chemical Society. 132: 5030-2. PMID 20369901 DOI: 10.1021/Ja101256V  0.781
2010 Xu H, Zuend SJ, Woll MG, Tao Y, Jacobsen EN. Asymmetric cooperative catalysis of strong Brønsted acid-promoted reactions using chiral ureas. Science (New York, N.Y.). 327: 986-90. PMID 20167783 DOI: 10.1126/Science.1182826  0.854
2010 Jacobsen E, McGowan M, Stevenson C, Schiffler M. Synthesis of (+)-Peloruside A Synfacts. 2010: 1330-1330. DOI: 10.1055/S-0030-1258875  0.799
2010 Jacobsen E, Veitch G. Highly Enantioselective Iodolactonization Synfacts. 2010: 1310-1310. DOI: 10.1055/S-0030-1258783  0.433
2010 Jacobsen E, Brown A, Kuo W. Catalytic Asymmetric α-Alkylation of Aldehydes with Benzhydryl Cations Synfacts. 2010: 1069-1069. DOI: 10.1055/s-0030-1257965  0.515
2010 Xu H, Zuend SJ, Woll MG, Tao Y, Jacobsen EN. Asymmetric Povarov Reactions Cobalt-Catalyzed by Chiral Ureas/AchiralAcids Synfacts. 2010: 601-601. DOI: 10.1055/S-0029-1219750  0.848
2010 Zuend SJ, Coughlin MP, Lalonde MP, Jacobsen EN. Gram-Scale Strecker Synthesis of Unnatural α-AminoAcids Synfacts. 2010: 108-108. DOI: 10.1055/S-0029-1218492  0.779
2010 SCHAUS SE, BRAANALT J, JACOBSEN EN. ChemInform Abstract: Asymmetric Hetero-Diels-Alder Reactions Catalyzed by Chiral (Salen)Chromium(III) Complexes. Cheminform. 29: no-no. DOI: 10.1002/chin.199825159  0.705
2010 LEIGHTON JL, JACOBSEN EN. ChemInform Abstract: Efficient Synthesis of (R)-4-((Trimethylsilyl)oxy)-2-cyclopentenone by Enantioselective Catalytic Epoxide Ring Opening. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199620079  0.328
2010 LARROW JF, JACOBSEN EN, GAO Y, HONG Y, NIE X, ZEPP CM. ChemInform Abstract: A Practical Method for the Large-Scale Preparation of (N,N′-Bis(3,5-di- tert-butylsalicylidene)-1,2-cyclohexanediaminato(2-))manganese(III) Chloride, a Highly Enantioselective Epoxidation Catalyst. Cheminform. 25: no-no. DOI: 10.1002/chin.199436210  0.353
2010 JACOBSEN EN. ChemInform Abstract: Asymmetric Catalytic Epoxidation of Unfunctionalized Olefins Cheminform. 25: no-no. DOI: 10.1002/CHIN.199431302  0.463
2009 Mita T, Jacobsen EN. Bifunctional Asymmetric Catalysis with Hydrogen Chloride: Enantioselective Ring-Opening of Aziridines Catalyzed by a Phosphinothiourea. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2009: 1680-1684. PMID 20161432 DOI: 10.1055/S-0029-1217344  0.532
2009 Zuend SJ, Coughlin MP, Lalonde MP, Jacobsen EN. Scaleable catalytic asymmetric Strecker syntheses of unnatural alpha-amino acids. Nature. 461: 968-70. PMID 19829379 DOI: 10.1038/Nature08484  0.834
2009 Zuend SJ, Jacobsen EN. Mechanism of amido-thiourea catalyzed enantioselective imine hydrocyanation: transition state stabilization via multiple non-covalent interactions. Journal of the American Chemical Society. 131: 15358-74. PMID 19778044 DOI: 10.1021/Ja9058958  0.825
2009 Peterson EA, Jacobsen EN. Enantioselective, thiourea-catalyzed intermolecular addition of indoles to cyclic N-acyl iminium ions. Angewandte Chemie (International Ed. in English). 48: 6328-31. PMID 19610008 DOI: 10.1002/Anie.200902420  0.601
2009 Loy RN, Jacobsen EN. Enantioselective intramolecular openings of oxetanes catalyzed by (salen)Co(III) complexes: access to enantioenriched tetrahydrofurans. Journal of the American Chemical Society. 131: 2786-7. PMID 19199427 DOI: 10.1021/Ja809176M  0.746
2009 Klausen RS, Jacobsen EN. Weak Brønsted acid-thiourea co-catalysis: enantioselective, catalytic protio-Pictet-Spengler reactions. Organic Letters. 11: 887-90. PMID 19178157 DOI: 10.1021/Ol802887H  0.846
2009 Mita T, Jacobsen EN. Bifunctional asymmetric catalysis with hydrogen chloride: Enantioselective ring opening of aziridines catalyzed by a phosphinothiourea Synlett. 1680-1684. DOI: 10.1055/s-0029-1217344  0.348
2009 Klausen RS, Jacobsen EN. Brønsted Acid-Thiourea Co-Catalysis Synfacts. 2009: 443-443. DOI: 10.1055/S-0028-1088101  0.678
2008 Groll M, Balskus EP, Jacobsen EN. Structural analysis of spiro beta-lactone proteasome inhibitors. Journal of the American Chemical Society. 130: 14981-3. PMID 18928262 DOI: 10.1021/Ja806059T  0.726
2008 Watson MP, Jacobsen EN. Asymmetric intramolecular arylcyanation of unactivated olefins via C-CN bond activation. Journal of the American Chemical Society. 130: 12594-5. PMID 18761453 DOI: 10.1021/Ja805094J  0.724
2008 Uyeda C, Jacobsen EN. Enantioselective Claisen rearrangements with a hydrogen-bond donor catalyst. Journal of the American Chemical Society. 130: 9228-9. PMID 18576616 DOI: 10.1021/Ja803370X  0.773
2008 Reisman SE, Doyle AG, Jacobsen EN. Enantioselective thiourea-catalyzed additions to oxocarbenium ions. Journal of the American Chemical Society. 130: 7198-9. PMID 18479086 DOI: 10.1021/Ja801514M  0.794
2008 Fang YQ, Jacobsen EN. Cooperative, highly enantioselective phosphinothiourea catalysis of imine-allene [3 + 2] cycloadditions. Journal of the American Chemical Society. 130: 5660-1. PMID 18393504 DOI: 10.1021/Ja801344W  0.548
2008 Raheem IT, Thiara PS, Jacobsen EN. Regio- and enantioselective catalytic cyclization of pyrroles onto N-acyliminium ions. Organic Letters. 10: 1577-80. PMID 18341346 DOI: 10.1021/Ol800256J  0.816
2008 Mergott DJ, Zuend SJ, Jacobsen EN. Catalytic asymmetric total synthesis of (+)-yohimbine. Organic Letters. 10: 745-8. PMID 18257582 DOI: 10.1021/Ol702781Q  0.848
2008 Mazet C, Jacobsen EN. Dinuclear {(salen)Al} complexes display expanded scope in the conjugate cyanation of alpha,beta-unsaturated imides. Angewandte Chemie (International Ed. in English). 47: 1762-5. PMID 18219639 DOI: 10.1002/Anie.200704461  0.696
2008 Grachan ML, Tudge MT, Jacobsen EN. Enantioselective catalytic carbonyl-ene cyclization reactions. Angewandte Chemie (International Ed. in English). 47: 1469-72. PMID 18188857 DOI: 10.1002/Anie.200704439  0.851
2008 Mergott DJ, Zuend SJ, Jacobsen EN. Synthesis of (+)-Yohimbine Synfacts. 2008: 793-793. DOI: 10.1055/S-2008-1078537  0.798
2008 Reisman SE, Doyle AG, Jacobsen EN. Enantioselective Additions to Oxocarbenium Ions via AnionBinding Synfacts. 2008: 1106-1106. DOI: 10.1055/S-2008-1078145  0.575
2008 Jacobsen E, Fang Y. A New Phosphinothiourea Catalyst Synfacts. 2008: 0755-0755. DOI: 10.1055/S-2008-1077815  0.324
2008 Grachan ML, Tudge MT, Jacobsen EN. Enantioselective Intramolecular Carbonyl-Ene Cyclization Synfacts. 2008: 383-383. DOI: 10.1055/S-2008-1042790  0.537
2008 Yoon TP, Jacobsen EN. ChemInform Abstract: Arenecarboxylic Acid Esters Cheminform. 39. DOI: 10.1002/chin.200849252  0.565
2008 Vanderwal CD, Jacobsen EN. ChemInform Abstract: Alk-2-enoic Acid Esters Cheminform. 39. DOI: 10.1002/chin.200849251  0.568
2008 Vanderwal CD, Jacobsen EN. ChemInform Abstract: Alk-2-enoic Acids Cheminform. 39. DOI: 10.1002/chin.200843262  0.547
2008 Belser T, Jacobsen E. Cooperative Catalysis in the Hydrolytic Kinetic Resolution of Epoxides by Chiral [(salen)Co(III)] Complexes Immobilized on Gold Colloids Advanced Synthesis & Catalysis. 350: 967-971. DOI: 10.1002/Adsc.200800028  0.498
2007 Doyle AG, Jacobsen EN. Small-molecule H-bond donors in asymmetric catalysis. Chemical Reviews. 107: 5713-43. PMID 18072808 DOI: 10.1021/Cr068373R  0.532
2007 Zuend SJ, Jacobsen EN. Cooperative catalysis by tertiary amino-thioureas: mechanism and basis for enantioselectivity of ketone cyanosilylation. Journal of the American Chemical Society. 129: 15872-83. PMID 18052247 DOI: 10.1021/Ja0735352  0.841
2007 Raheem IT, Thiara PS, Peterson EA, Jacobsen EN. Enantioselective Pictet-Spengler-type cyclizations of hydroxylactams: H-bond donor catalysis by anion binding. Journal of the American Chemical Society. 129: 13404-5. PMID 17941641 DOI: 10.1021/Ja076179W  0.776
2007 Balskus EP, Jacobsen EN. Asymmetric catalysis of the transannular Diels-Alder reaction. Science (New York, N.Y.). 317: 1736-40. PMID 17885133 DOI: 10.1126/Science.1146939  0.828
2007 Doyle AG, Jacobsen EN. Enantioselective alkylation of acyclic alpha,alpha-disubstituted tributyltin enolates catalyzed by a {Cr(salen)} complex. Angewandte Chemie (International Ed. in English). 46: 3701-5. PMID 17407117 DOI: 10.1002/Anie.200604901  0.551
2007 Tan KL, Jacobsen EN. Indium-mediated asymmetric allylation of acylhydrazones using a chiral urea catalyst. Angewandte Chemie (International Ed. in English). 46: 1315-7. PMID 17211916 DOI: 10.1002/Anie.200603354  0.708
2007 Jacobsen E, Doyle A. Asymmetric α-Alkylation of Acyclic Tin Enolates Synfacts. 2007: 0732-0732. DOI: 10.1055/s-2007-968614  0.533
2007 Jacobsen E, Tan K. Asymmetric Allylation of Acylhydrazones Synfacts. 2007: 0435-0435. DOI: 10.1055/S-2007-968345  0.691
2006 Lalonde MP, Chen Y, Jacobsen EN. A chiral primary amine thiourea catalyst for the highly enantioselective direct conjugate addition of alpha,alpha-disubstituted aldehydes to nitroalkenes. Angewandte Chemie (International Ed. in English). 45: 6366-70. PMID 16937417 DOI: 10.1002/Anie.200602221  0.819
2006 Huang H, Jacobsen EN. Highly enantioselective direct conjugate addition of ketones to nitroalkenes promoted by a chiral primary amine-thiourea catalyst. Journal of the American Chemical Society. 128: 7170-1. PMID 16734464 DOI: 10.1021/Ja0620890  0.568
2006 Balskus EP, Jacobsen EN. Alpha,beta-unsaturated beta-silyl imide substrates for catalytic, enantioselective conjugate additions: a total synthesis of (+)-lactacystin and the discovery of a new proteasome inhibitor. Journal of the American Chemical Society. 128: 6810-2. PMID 16719460 DOI: 10.1021/Ja061970A  0.759
2006 Taylor MS, Jacobsen EN. Asymmetric catalysis by chiral hydrogen-bond donors. Angewandte Chemie (International Ed. in English). 45: 1520-43. PMID 16491487 DOI: 10.1002/Anie.200503132  0.537
2006 Jacobsen E, Balskus E. Synthesis of (+)-Lactacystin Synfacts. 2006: 1202-1202. DOI: 10.1055/S-2006-955595  0.748
2006 Jacobsen E, Lalonde M, Chen Y. Conjugate Addition of α,α-Disubstituted Aldehydes to Nitroalkenes Synfacts. 2006: 1170-1170. DOI: 10.1055/S-2006-949458  0.766
2006 Jacobsen E, Huang H. Chiral Amine-Thiourea Catalyst for the Asymmetric Michael Addition Synfacts. 2006: 0727-0727. DOI: 10.1055/S-2006-941907  0.441
2006 Boezio A, Jarvo ER, Lawrence BM, Jacobsen EN. Synthesis of (-)-Colombiasin A and(-)-Elisapterosin B Synfacts. 2006: 196-196. DOI: 10.1055/S-2006-931920  0.624
2006 Taylor MS, Jacobsen EN. Asymmetrische Katalyse durch chirale Wasserstoffbrückendonoren Angewandte Chemie. 118: 1550-1573. DOI: 10.1002/Ange.200503132  0.443
2006 Nielsen LPC, Jacobsen EN. Catalytic Asymmetric Epoxide Ring-opening Chemistry Aziridines and Epoxides in Organic Synthesis. 229-269. DOI: 10.1002/3527607862.ch7  0.339
2006 Stevenson CP, Nielsen LPC, Jacobsen EN. Preparation of (S)-methyl glycidate via hydrolytic kinetic resolution Organic Syntheses. 83: 162-169. DOI: 10.1002/0471264229.Os083.21  0.786
2005 Taylor MS, Tokunaga N, Jacobsen EN. Enantioselective thiourea-catalyzed acyl-mannich reactions of isoquinolines. Angewandte Chemie (International Ed. in English). 44: 6700-4. PMID 16175644 DOI: 10.1002/Anie.200502277  0.62
2005 Jarvo ER, Lawrence BM, Jacobsen EN. Highly enantio- and regioselective quinone Diels-Alder reactions catalyzed by a tridentate [(Schiff Base)Cr(III)] complex. Angewandte Chemie (International Ed. in English). 44: 6043-6. PMID 16134190 DOI: 10.1002/Anie.200502176  0.786
2005 Boezio AA, Jarvo ER, Lawrence BM, Jacobsen EN. Efficient total syntheses of (-)-colombiasin A and (-)-elisapterosin B: application of the Cr-catalyzed asymmetric quinone Diels-Alder reaction. Angewandte Chemie (International Ed. in English). 44: 6046-50. PMID 16108082 DOI: 10.1002/Anie.200502178  0.816
2005 Fuerst DE, Jacobsen EN. Thiourea-catalyzed enantioselective cyanosilylation of ketones. Journal of the American Chemical Society. 127: 8964-5. PMID 15969569 DOI: 10.1021/Ja052511X  0.547
2005 Gandelman M, Jacobsen EN. Highly enantioselective catalytic conjugate addition of N-heterocycles to alpha,beta-unsaturated ketones and imides. Angewandte Chemie (International Ed. in English). 44: 2393-7. PMID 15761885 DOI: 10.1002/Anie.200463058  0.624
2005 Taylor MS, Zalatan DN, Lerchner AM, Jacobsen EN. Highly enantioselective conjugate additions to alpha,beta-unsaturated ketones catalyzed by a (salen)Al complex. Journal of the American Chemical Society. 127: 1313-7. PMID 15669872 DOI: 10.1021/Ja044999S  0.553
2005 Doyle AG, Jacobsen EN. Enantioselective alkylations of tributyltin enolates catalyzed by Cr(salen)Cl: access to enantiomerically enriched all-carbon quaternary centers. Journal of the American Chemical Society. 127: 62-3. PMID 15631449 DOI: 10.1021/Ja043601P  0.662
2005 Yoon TP, Jacobsen EN. Highly enantioselective thiourea-catalyzed nitro-Mannich reactions. Angewandte Chemie (International Ed. in English). 44: 466-8. PMID 15624148 DOI: 10.1002/Anie.200461814  0.729
2005 Jacobsen E, Raheem I. Thiourea Derivative Catalyzed Asymmetric Aza-Baylis-Hillman Reaction Synfacts. 2006: 0075-0075. DOI: 10.1055/s-2005-921710  0.802
2005 Jarvo ER, Lawrence BM, Jacobsen EN. Quinone Diels-Alder Reactions Catalyzed by a [(Schiff Base)CrIII] Complex Synfacts. 2005: 305-305. DOI: 10.1055/S-2005-921640  0.7
2005 Jacobsen EN, Pfaltz A, Shibasaki M. Catalytic C-C bond formation Advanced Synthesis and Catalysis. 347: 1471. DOI: 10.1002/Adsc.200505313  0.502
2005 Raheem IT, Jacobsen EN. Highly enantioselective aza-Baylis-Hillman reactions catalyzed by chiral thiourea derivatives Advanced Synthesis and Catalysis. 347: 1701-1708. DOI: 10.1002/Adsc.200505230  0.824
2005 Wenzel AG, Jacobsen EN. Asymmetric Catalysis in Enantioselective Synthesis of β-Amino Acids Enantioselective Synthesis of β-Amino Acids: Second Edition. 107-115. DOI: 10.1002/0471698482.ch4  0.768
2005 Chavez DE, Jacobsen EN. An efficient, highly diastereo- and enantioselective hetero-Diels-Alder catalyst. Preparation of (2S,6R)-6-(tert-butyldimethyl-silyloxymethyl)-2- methoxy-2,5-dihydropyran Organic Syntheses. 82: 34-42. DOI: 10.1002/0471264229.Os082.06  0.685
2004 Vanderwal CD, Jacobsen EN. Enantioselective formal hydration of alpha,beta-unsaturated imides by Al-catalyzed conjugate addition of oxime nucleophiles. Journal of the American Chemical Society. 126: 14724-5. PMID 15535689 DOI: 10.1021/Ja045563F  0.701
2004 Taylor MS, Jacobsen EN. Highly enantioselective catalytic acyl-pictet-spengler reactions. Journal of the American Chemical Society. 126: 10558-9. PMID 15327311 DOI: 10.1021/Ja046259P  0.674
2004 Sammis GM, Danjo H, Jacobsen EN. Cooperative dual catalysis: application to the highly enantioselective conjugate cyanation of unsaturated imides. Journal of the American Chemical Society. 126: 9928-9. PMID 15303860 DOI: 10.1021/Ja046653N  0.763
2004 Kim SK, Jacobsen EN. General catalytic synthesis of highly enantiomerically enriched terminal aziridines from racemic epoxides. Angewandte Chemie (International Ed. in English). 43: 3952-4. PMID 15274223 DOI: 10.1002/Anie.200460369  0.622
2004 Joly GD, Jacobsen EN. Thiourea-catalyzed enantioselective hydrophosphonylation of imines: practical access to enantiomerically enriched alpha-amino phosphonic acids. Journal of the American Chemical Society. 126: 4102-3. PMID 15053588 DOI: 10.1021/Ja0494398  0.774
2004 Taylor MS, Jacobsen EN. Asymmetric catalysis in complex target synthesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 5368-73. PMID 15020767 DOI: 10.1073/Pnas.0307893101  0.658
2004 Nielsen LP, Stevenson CP, Blackmond DG, Jacobsen EN. Mechanistic investigation leads to a synthetic improvement in the hydrolytic kinetic resolution of terminal epoxides. Journal of the American Chemical Society. 126: 1360-2. PMID 14759192 DOI: 10.1021/Ja038590Z  0.838
2004 Raheem IT, Goodman SN, Jacobsen EN. Catalytic asymmetric total syntheses of quinine and quinidine. Journal of the American Chemical Society. 126: 706-7. PMID 14733531 DOI: 10.1021/Ja039550Y  0.808
2004 Keith JM, Jacobsen EN. Asymmetric hydrocyanation of hydrazones catalyzed by lanthanide--PYBOX complexes. Organic Letters. 6: 153-5. PMID 14723516 DOI: 10.1021/Ol035844C  0.551
2003 Taylor MS, Jacobsen EN. Enantioselective Michael additions to alpha,beta-unsaturated imides catalyzed by a Salen-Al complex. Journal of the American Chemical Society. 125: 11204-5. PMID 16220935 DOI: 10.1021/Ja037177O  0.589
2003 Ruck RT, Jacobsen EN. Asymmetric hetero-ene reactions of trimethylsilyl enol ethers catalyzed by tridentate Schiff base chromium(III) complexes. Angewandte Chemie (International Ed. in English). 42: 4771-4. PMID 14562344 DOI: 10.1002/Anie.200351591  0.753
2003 Chavez DE, Jacobsen EN. Catalyst-controlled inverse-electron-demand hetero-Diels-Alder reactions in the enantio- and diastereoselective synthesis of iridoid natural products. Organic Letters. 5: 2563-5. PMID 12841781 DOI: 10.1021/Ol034883L  0.751
2003 Sammis GM, Jacobsen EN. Highly enantioselective, catalytic conjugate addition of cyanide to alpha,beta-unsaturated imides. Journal of the American Chemical Society. 125: 4442-3. PMID 12683813 DOI: 10.1021/Ja034635K  0.72
2003 Yoon TP, Jacobsen EN. Privileged chiral catalysts. Science (New York, N.Y.). 299: 1691-3. PMID 12637734 DOI: 10.1126/Science.1083622  0.734
2003 Wenzel AG, Lalonde MP, Jacobsen EN. Divergent Stereoinduction Mechanisms in Urea-Catalyzed Additions to Imines Synlett. 1919-1922. DOI: 10.1055/S-2003-41503  0.856
2003 White DE, Jacobsen EN. New oligomeric catalyst for the hydrolytic kinetic resolution of terminal epoxides under solvent-free conditions Tetrahedron Asymmetry. 14: 3633-3638. DOI: 10.1016/J.Tetasy.2003.09.024  0.661
2003 Larrow JF, Roberts E, Verhoeven TR, Ryan KM, Senanayake CH, Reider PJ, Jacobsen EN. (1S,2R)‐1‐Aminoindan‐2‐ol Organic Syntheses. 76: 46-46. DOI: 10.1002/0471264180.Os076.06  0.477
2003 Larrow JF, Jacobsen EN. (R,R)‐N,N′‐Bis(3,5‐di‐tert‐Butylsalicylidene)‐1,2‐Cyclohexanediamino Manganese(III) Chloride, A Highly Enantioselective Epoxidation Catalyst Organic Syntheses. 1-1. DOI: 10.1002/0471264180.Os075.01  0.331
2002 Ready JM, Jacobsen EN. A practical oligomeric [(salen)Co] catalyst for asymmetric epoxide ring-opening reactions. Angewandte Chemie (International Ed. in English). 41: 1374-7. PMID 19750769 DOI: 10.1002/1521-3773(20020415)41:8<1374::Aid-Anie1374>3.0.Co;2-8  0.701
2002 Goodman SN, Jacobsen EN. Enantiopure beta-hydroxy morpholine amides from terminal epoxides by carbonylation at 1 atm. Angewandte Chemie (International Ed. in English). 41: 4703-5. PMID 12481332 DOI: 10.1002/Anie.200290022  0.486
2002 Movassaghi M, Jacobsen EN. Chemistry. The simplest "enzyme". Science (New York, N.Y.). 298: 1904-5. PMID 12471240 DOI: 10.1126/Science.1076547  0.526
2002 Wenzel AG, Jacobsen EN. Asymmetric catalytic Mannich reactions catalyzed by urea derivatives: enantioselective synthesis of beta-aryl-beta-amino acids. Journal of the American Chemical Society. 124: 12964-5. PMID 12405820 DOI: 10.1021/Ja028353G  0.827
2002 Gademann K, Chavez DE, Jacobsen EN. Highly enantioselective inverse-electron-demand hetero-diels-alder reactions of alpha,beta-unsaturated aldehydes. Angewandte Chemie (International Ed. in English). 41: 3059-61. PMID 12203458 DOI: 10.1002/1521-3773(20020816)41:16<3059::Aid-Anie3059>3.0.Co;2-I  0.781
2002 Vachal P, Jacobsen EN. Structure-based analysis and optimization of a highly enantioselective catalyst for the strecker reaction. Journal of the American Chemical Society. 124: 10012-4. PMID 12188665 DOI: 10.1021/Ja027246J  0.797
2002 Joly GD, Jacobsen EN. Catalyst-controlled diastereoselective hetero-Diels-Alder reactions. Organic Letters. 4: 1795-8. PMID 12000301 DOI: 10.1021/Ol0258785  0.837
2002 Ruck RT, Jacobsen EN. Asymmetric catalysis of hetero-ene reactions with tridentate Schiff base chromium(III) complexes. Journal of the American Chemical Society. 124: 2882-3. PMID 11902873 DOI: 10.1021/Ja025588J  0.738
2002 Movassaghi M, Jacobsen EN. A direct method for the conversion of terminal epoxides into gamma-butanolides. Journal of the American Chemical Society. 124: 2456-7. PMID 11890792 DOI: 10.1021/Ja025604C  0.679
2002 Schaus SE, Brandes BD, Larrow JF, Tokunaga M, Hansen KB, Gould AE, Furrow ME, Jacobsen EN. Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen)Co(III) complexes. Practical synthesis of enantioenriched terminal epoxides and 1,2-diols. Journal of the American Chemical Society. 124: 1307-15. PMID 11841300 DOI: 10.1021/Ja016737L  0.79
2002 Movassaghi M, Jacobsen EN. A direct method for the conversion of terminal epoxides into γ-butanolides Journal of the American Chemical Society. 124: 2456-2457. DOI: 10.1021/ja025604c  0.527
2002 Goodman SN, Jacobsen EN. A Practical Synthesis of α,β-Unsaturated Imides, Useful Substrates for Asymmetric Conjugate Addition Reactions Advanced Synthesis and Catalysis. 344: 953-956. DOI: 10.1002/1615-4169(200210)344:9<953::Aid-Adsc953>3.0.Co;2-A  0.47
2002 Jacobsen E. Advanced Synthesis & Catalysis Enters Its Second Year Advanced Synthesis & Catalysis. 344: 1. DOI: 10.1002/1615-4169(200201)344:1<1::Aid-Adsc1>3.0.Co;2-A  0.352
2002 Gademann K, Chavez DE, Jacobsen EN. Highly Enantioselective Inverse-Electron-Demand Hetero-DielsâAlder Reactions of α,β-Unsaturated Aldehydes This work was supported by the NIH (GM-59316), with additional support from the Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung (postdoctoral fellowship to K.G.), and the National Science Foundation (predoctoral fellowship to D.E.C.). We are grateful to Dr. R. Staples for carrying out the X-ray crystal structure analysis of 1. Angewandte Chemie. 114: 3059. DOI: 10.1002/1521-3757(20020816)114:16<3185::Aid-Ange3185>3.0.Co;2-S  0.573
2002 Ready JM, Jacobsen EN. A Practical Oligomeric [(salen)Co] Catalyst for Asymmetric Epoxide Ring-Opening Reactions This work was supported by the NIH (GM 43214). H2salen=bis(salicylidene)ethylenediamine. Angewandte Chemie. 114: 1432. DOI: 10.1002/1521-3757(20020415)114:8<1432::Aid-Ange1432>3.0.Co;2-6  0.517
2001 Thompson CF, Jamison TF, Jacobsen EN. FR901464: total synthesis, proof of structure, and evaluation of synthetic analogues. Journal of the American Chemical Society. 123: 9974-83. PMID 11592876 DOI: 10.1021/Ja016615T  0.663
2001 Chavez DE, Jacobsen EN. Total Synthesis of Fostriecin (CI-920) We thank Professor Andrew G. Myers and Scott E. Schaus for helpful discussions, and Dr. Alexandra E. Gould and Isabel K. Reichardt for important preliminary experimental work. We also thank Dr. Robert J. Schultz of the Drug Synthesis and Chemistry Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer institute, for a sample of natural fostriecin. This work was supported by the NIH (GM-59316), and by Beinecke Memorial and NSF predoctoral fellowships to D.E.C. Angewandte Chemie (International Ed. in English). 40: 3667-3670. PMID 11592216 DOI: 10.1002/1521-3773(20011001)40:19<3667::Aid-Anie3667>3.0.Co;2-6  0.672
2001 White MC, Doyle AG, Jacobsen EN. A synthetically useful, self-assembling MMO mimic system for catalytic alkene epoxidation with aqueous H2O2. Journal of the American Chemical Society. 123: 7194-5. PMID 11459514 DOI: 10.1021/Ja015884G  0.725
2001 Ready JM, Jacobsen EN. Highly active oligomeric (salen)co catalysts for asymmetric epoxide ring-opening reactions. Journal of the American Chemical Society. 123: 2687-8. PMID 11456948 DOI: 10.1021/Ja005867B  0.711
2001 Brandes BD, Jacobsen EN. Regioselective ring opening of enantiomerically enriched epoxides via catalysis with chiral (salen)Cr(III) complexes Synlett. 1013-1015. DOI: 10.1055/S-2001-14649  0.387
2001 Buchwald S, Burk M, Jacobsen E, Kobayashi S, Pfaltz A, Wong C. Nobel Prizes in Chemistry 2001; Congratulations from the Editors Advanced Synthesis & Catalysis. 343: 753-753. DOI: 10.1002/1615-4169(20011231)343:8<753::Aid-Adsc753>3.0.Co;2-9  0.507
2001 Su JT, Vachal P, Jacobsen EN. Practical Synthesis of a Soluble Schiff Base Catalyst for the Asymmetric Strecker Reaction Advanced Synthesis and Catalysis. 343: 197-200. DOI: 10.1002/1615-4169(20010226)343:2<197::Aid-Adsc197>3.0.Co;2-8  0.807
2001 Keith JM, Larrow JF, Jacobsen EN. Practical Considerations in Kinetic Resolution Reactions Advanced Synthesis and Catalysis. 343: 5-26. DOI: 10.1002/1615-4169(20010129)343:1<5::Aid-Adsc5>3.0.Co;2-I  0.499
2000 Breinbauer R, Jacobsen EN. Cooperative Asymmetric Catalysis with Dendrimeric Angewandte Chemie (International Ed. in English). 39: 3604-3607. PMID 11091412 DOI: 10.1002/1521-3773(20001016)39:20<3604::Aid-Anie3604>3.0.Co;2-9  0.67
2000 Jacobsen EN. Asymmetric catalysis of epoxide ring-opening reactions. Accounts of Chemical Research. 33: 421-31. PMID 10891060 DOI: 10.1021/Ar960061V  0.56
2000 Denmark SE, Jacobsen EN. Catalytic asymmetric synthesis. Accounts of Chemical Research. 33: 324. PMID 10891049 DOI: 10.1021/Ar000046X  0.537
2000 Schaus SE, Jacobsen EN. Asymmetric ring opening of meso epoxides with TMSCN catalyzed by (pybox)lanthanide complexes. Organic Letters. 2: 1001-4. PMID 10768207 DOI: 10.1021/Ol005721H  0.73
2000 Sigman MS, Vachal P, Jacobsen EN. A General Catalyst for the Asymmetric Strecker Reaction This work was supported by the NIH (GM-43214). A postdoctoral fellowship to M.S.S. (NIH), and a predoctoral fellowship to P.V. sponsored by Alfred Bader are gratefully acknowledged. Angewandte Chemie (International Ed. in English). 39: 1279-1281. PMID 10767031 DOI: 10.1002/(Sici)1521-3773(20000403)39:7<1279::Aid-Anie1279>3.0.Co;2-U  0.792
2000 Vachal P, Jacobsen EN. Enantioselective catalytic addition of HCN to ketoimines. Catalytic synthesis of quaternary amino acids. Organic Letters. 2: 867-70. PMID 10754690 DOI: 10.1021/Ol005636+  0.774
2000 Jacobsen EN, Breinbauer R. Nickel comes full cycle Science. 287: 437-438. DOI: 10.1126/Science.287.5452.437  0.608
2000 Thompson CF, Jamison TF, Jacobsen EN. Total synthesis of FR901464. Convergent assembly of chiral components prepared by asymmetric catalysis [17] Journal of the American Chemical Society. 122: 10482-10483. DOI: 10.1021/Ja0055357  0.636
2000 Foote CS, Jacobsen EN. Catalytic asymmetric synthesis special issue: Editorial Accounts of Chemical Research. 33: 323. DOI: 10.1021/ar0000455  0.397
2000 Breinbauer R, Jacobsen EN. Cooperative asymmetric catalysis with dendrimer bound [Co(salen)] catalysts Angewandte Chemie. 39: 3604-3607. DOI: 10.1002/1521-3773(20001016)39:20<3604::Aid-Anie3604>3.0.Co;2  0.672
1999 Wu MH, Hansen KB, Jacobsen EN. Regio- and Enantioselective Cyclization of Epoxy Alcohols Catalyzed by a [Co(salen)] Complex. Angewandte Chemie (International Ed. in English). 38: 2012-2014. PMID 34182660 DOI: 10.1002/(SICI)1521-3773(19990712)38:13/14<2012::AID-ANIE2012>3.0.CO;2-H  0.547
1999 Francis MB, Jacobsen EN. Discovery of Novel Catalysts for Alkene Epoxidation from Metal-Binding Combinatorial Libraries. Angewandte Chemie (International Ed. in English). 38: 937-941. PMID 29711875 DOI: 10.1002/(Sici)1521-3773(19990401)38:7<937::Aid-Anie937>3.0.Co;2-O  0.646
1999 Li Z, Fernández M, Jacobsen EN. Enantioselective ring opening of meso aziridines catalyzed by Tridentate Schiff base chromium(III) complexes. Organic Letters. 1: 1611-3. PMID 10836024 DOI: 10.1021/Ol990992H  0.483
1999 Peukert S, Jacobsen EN. Enantioselective parallel synthesis using polymer-supported chiral Co(salen) complexes. Organic Letters. 1: 1245-8. PMID 10825975 DOI: 10.1021/Ol990920Q  0.463
1999 Dossetter AG, Jamison TF, Jacobsen EN. Highly Enantio- and Diastereoselective Hetero-Diels-Alder Reactions Catalyzed by New Chiral Tridentate Chromium(III) Catalysts. Angewandte Chemie (International Ed. in English). 38: 2398-2400. PMID 10458800 DOI: 10.1002/(Sici)1521-3773(19990816)38:16<2398::Aid-Anie2398>3.0.Co;2-E  0.726
1999 Hinterding K, Jacobsen EN. Regioselective carbomethoxylation of chiral epoxides: A new route to enantiomerically pure β-hydroxy esters Journal of Organic Chemistry. 64: 2164-2165. DOI: 10.1021/Jo982336L  0.395
1999 Myers JK, Jacobsen EN. Asymmetric synthesis of β-amino acid derivatives via catalytic conjugate addition of hydrazoic acid to unsaturated imides [10] Journal of the American Chemical Society. 121: 8959-8960. DOI: 10.1021/Ja991621Z  0.386
1999 Ready JM, Jacobsen EN. Asymmetric catalytic synthesis of α-aryloxy alcohols: Kinetic resolution of terminal epoxides via highly enantioselective ring-opening with phenols Journal of the American Chemical Society. 121: 6086-6087. DOI: 10.1021/Ja9910917  0.67
1999 Annis DA, Jacobsen EN. Polymer-supported chiral Co(salen) complexes: Synthetic applications and mechanistic investigations in the hydrolytic kinetic resolution of terminal epoxides Journal of the American Chemical Society. 121: 4147-4154. DOI: 10.1021/Ja984410N  0.84
1999 Lebel H, Jacobsen EN. Chromium catalyzed kinetic resolution of 2,2-disubstituted epoxides Tetrahedron Letters. 40: 7303-7306. DOI: 10.1016/S0040-4039(99)01502-6  0.511
1999 Wu MH, Hansen KB, Jacobsen EN. Regio- and enantioselective cyclization of epoxy alcohols catalyzed by a [Co(III)(salen)] complex Angewandte Chemie - International Edition. 38: 2012-2014. DOI: 10.1002/(Sici)1521-3773(19990712)38:13/14<2012::Aid-Anie2012>3.0.Co;2-H  0.599
1999 Francis MB, Jacobsen EN. Discovery of novel catalysts for alkene epoxidation from metal-binding combinatorial libraries Angewandte Chemie - International Edition. 38: 937-941. DOI: 10.1002/(SICI)1521-3773(19990401)38:7<937::AID-ANIE937>3.0.CO;2-O  0.575
1999 Dossetter A, Jamison T, Jacobsen E. Hochenantio- und -diastereoselektive Hetero-Diels-Alder-Reaktionen, katalyisert durch neue chirale Chrom(III)-Komplexe Angewandte Chemie. 111: 2549-2552. DOI: 10.1002/(Sici)1521-3757(19990816)111:16<2549::Aid-Ange2549>3.0.Co;2-H  0.625
1999 Francis MB, Jacobsen EN. Entdeckung neuer Katalysatoren für die Alkenepoxidierung durch metallbindende kombinatorische Bibliotheken Angewandte Chemie. 111: 987-991. DOI: 10.1002/(Sici)1521-3757(19990401)111:7<987::Aid-Ange987>3.0.Co;2-9  0.478
1998 Furrow ME, Schaus SE, Jacobsen EN. Practical Access to Highly Enantioenriched C-3 Building Blocks via Hydrolytic Kinetic Resolution. The Journal of Organic Chemistry. 63: 6776-6777. PMID 11672291 DOI: 10.1021/Jo981332D  0.607
1998 Francis MB, Jamison TF, Jacobsen EN. Combinatorial libraries of transition-metal complexes, catalysts and materials. Current Opinion in Chemical Biology. 2: 422-8. PMID 9691076 DOI: 10.1016/S1367-5931(98)80019-7  0.706
1998 Lebel H, Jacobsen EN. Enantioselective total synthesis of taurospongin A Journal of Organic Chemistry. 63: 9624-9625. DOI: 10.1021/Jo9819741  0.462
1998 Schaus SE, Brånalt J, Jacobsen EN. Total synthesis of muconin by efficient assembly of chiral building blocks Journal of Organic Chemistry. 63: 4876-4877. DOI: 10.1021/Jo9810765  0.653
1998 Wu MH, Jacobsen EN. Asymmetric Ring Opening of Meso Epoxides with Thiols: Enantiomeric Enrichment Using a Bifunctional Nucleophile Journal of Organic Chemistry. 63: 5252-5254. DOI: 10.1021/Jo980155D  0.398
1998 Schaus SE, Brånalt J, Jacobsen EN. Asymmetric Hetero-Diels−Alder Reactions Catalyzed by Chiral (Salen)Chromium(III) Complexes The Journal of Organic Chemistry. 63: 403-405. DOI: 10.1021/Jo971758C  0.727
1998 Konsler RG, Karl J, Jacobsen EN. Cooperative asymmetric catalysis with dimeric salen complexes [11] Journal of the American Chemical Society. 120: 10780-10781. DOI: 10.1021/Ja982683C  0.535
1998 Sigman MS, Jacobsen EN. Enantioselective addition of hydrogen cyanide to imines catalyzed by a chiral (salen)Al(III) complex [1] Journal of the American Chemical Society. 120: 5315-5316. DOI: 10.1021/Ja980299+  0.619
1998 Sigman MS, Jacobsen EN. Schiff base catalysts for the asymmetric strecker reaction identified and optimized from parallel synthetic libraries Journal of the American Chemical Society. 120: 4901-4902. DOI: 10.1021/Ja980139Y  0.658
1998 Palucki M, Finney NS, Pospisil PJ, Güler ML, Ishida T, Jacobsen EN. The mechanistic basis for electronic effects on enantioselectivity in the (salen)Mn(III)-catalyzed epoxidation reaction Journal of the American Chemical Society. 120: 948-954. DOI: 10.1021/Ja973468J  0.499
1998 Dakin LA, Schaus SE, Jacobsen EN, Panek JS. Carbenoid insertions into the silicon-hydrogen bond catalyzed by chiral copper (I) Schiff base complexes Tetrahedron Letters. 39: 8947-8950. DOI: 10.1016/S0040-4039(98)02013-9  0.714
1998 Zamojski A, Jacobsen EN, Kakiuchi F, Konsler RG, Larrow JF, Tokunaga M. Enantioselective catalytic ring opening of epoxides with carboxylic acids Chemtracts. 11: 287-290. DOI: 10.1016/S0040-4039(96)02414-8  0.709
1998 Annis DA, Helluin O, Jacobsen EN. Stereochemistry as a diversity element: Solid-phase synthesis of cyclic RGD peptide derivatives by asymmetric catalysis Angewandte Chemie - International Edition. 37: 1907-1909. DOI: 10.1002/(Sici)1521-3773(19980803)37:13/14<1907::Aid-Anie1907>3.0.Co;2-A  0.774
1997 Tokunaga M, Larrow JF, Kakiuchi F, Jacobsen EN. Asymmetric catalysis with water: efficient kinetic resolution of terminal epoxides by means of catalytic hydrolysis. Science (New York, N.Y.). 277: 936-8. PMID 9252321 DOI: 10.1126/Science.277.5328.936  0.711
1997 Schaus SE, Larrow JF, Jacobsen EN. Practical Synthesis of Enantiopure Cyclic 1,2-Amino Alcohols via Catalytic Asymmetric Ring Opening of Meso Epoxides The Journal of Organic Chemistry. 62: 4197-4199. DOI: 10.1021/Jo970146P  0.671
1997 Brandes BD, Jacobsen EN. Synthesis of enantiopure 3-chlorostyrene oxide via an asymmetric epoxidation-hydrolytic kinetic resolution sequence Tetrahedron Asymmetry. 8: 3927-3933. DOI: 10.1016/S0957-4166(97)00568-5  0.494
1997 Wu MH, Jacobsen EN. An efficient formal synthesis of balanol via the asymmetric epoxide ring opening reaction Tetrahedron Letters. 38: 1693-1696. DOI: 10.1016/S0040-4039(97)00192-5  0.5
1997 Finney NS, Pospisil PJ, Chang S, Palucki M, Konsler RG, Hansen KB, Jacobsen EN. On the Viability of Oxametallacyclic Intermediates in the(salen)Mn-Catalyzed Asymmetric Epoxidation Angewandte Chemie International Edition in English. 36: 1720-1723. DOI: 10.1002/Anie.199717201  0.594
1997 Finney NS, Pospisil PJ, Chang S, Palucki M, Konsler RG, Hansen KB, Jacobsen EN. Zum Auftreten von oxametallacyclischen Intermediaten in der [Mn(salen)]-katalysierten asymmetrischen Epoxidierung Angewandte Chemie. 109: 1798-1801. DOI: 10.1002/Ange.19971091614  0.378
1996 Martínez LE, Nugent WA, Jacobsen EN. Highly Efficient and Enantioselective Synthesis of Carbocyclic Nucleoside Analogs Using Selective Early Transition Metal Catalysis. The Journal of Organic Chemistry. 61: 7963-7966. PMID 11667763 DOI: 10.1021/Jo961241L  0.371
1996 Leighton JL, Jacobsen EN. Efficient synthesis of (R)-4-(trimethylsilyl)oxy)-2-cyclopentenone by enantioselective catalytic epoxide ring opening Journal of Organic Chemistry. 61: 389-390. DOI: 10.1021/Jo951557D  0.671
1996 Hansen KB, Leighton JL, Jacobsen EN. On the mechanism of asymmetric nucleophilic ring-opening of epoxides catalyzed by (salen)Cr(III) complexes Journal of the American Chemical Society. 118: 10924-10925. DOI: 10.1021/Ja962600X  0.705
1996 Francis MB, Finney NS, Jacobsen EN. Combinatorial approach to the discovery of novel coordination complexes Journal of the American Chemical Society. 118: 8983-8984. DOI: 10.1021/Ja961842U  0.52
1996 Quan RW, Li Z, Jacobsen EN. Enantiofacially Selective Binding of Prochiral Olefins to a Chiral Catalyst via Simultaneous Face−Face and Edge−Face Aromatic Interactions Journal of the American Chemical Society. 118: 8156-8157. DOI: 10.1021/Ja9618098  0.459
1996 Larrow JF, Schaus SE, Jacobsen EN. Kinetic resolution of terminal epoxides via highly regioselective and enantioselective ring opening with TMSN3. An efficient, catalytic route to 1,2-amino alcohols Journal of the American Chemical Society. 118: 7420-7421. DOI: 10.1021/Ja961708+  0.679
1996 Schaus SE, Jacobsen EN. Dynamic kinetic resolution of epichlorohydrin via enantioselective catalytic ring opening with TMSN3. Practical synthesis of aryl oxazolidinone antibacterial agents Tetrahedron Letters. 37: 7937-7940. DOI: 10.1016/0040-4039(96)01835-7  0.706
1996 Pospisil PJ, Carsten DH, Jacobsen EN. X-Ray Structural Studies of Highly Enantioselective Mn(salen) Epoxidation Catalysts Chemistry - a European Journal. 2: 974-980. DOI: 10.1002/Chem.19960020812  0.466
1995 Velde SLV, Jacobsen EN. Kinetic Resolution Of Racemic Chromenes Via Asymmetric Epoxidation : Synthesis Of (+)-Teretifolione B Journal of Organic Chemistry. 60: 5380-5381. DOI: 10.1021/Jo00122A008  0.396
1995 Martínez LE, Leighton JL, Carsten DH, Jacobsen EN. Highly enantioselective ring opening of epoxides catalyzed by (salen)Cr(III) complexes Journal of the American Chemical Society. 117: 5897-5898. DOI: 10.1021/Ja00126A048  0.637
1995 Li Z, Quan RW, Jacobsen EN. Mechanism of the (Diimine)copper-Catalyzed Asymmetric Aziridination of Alkenes. Nitrene Transfer via Ligand-Accelerated Catalysis Journal of the American Chemical Society. 117: 5889-5890. DOI: 10.1021/Ja00126A044  0.365
1995 Palucki M, McCormick GJ, Jacobsen EN. Low temperature asymmetric epoxidation of unfunctionalized olefins catalyzed by (salen)Mn(III) complexes Tetrahedron Letters. 36: 5457-5460. DOI: 10.1016/0040-4039(95)01088-Y  0.451
1995 Brandes BD, Jacobsen EN. Enantioselective catalytic epoxidation of tetrasubstituted olefins Tetrahedron Letters. 36: 5123-5126. DOI: 10.1016/0040-4039(95)00965-F  0.555
1995 Hansen KB, Finney NS, Jacobsen EN. Carbenoid Transfer to Imines: A New Asymmetric Catalytic Synthesis of Aziridines Angewandte Chemie International Edition in English. 34: 676-678. DOI: 10.1002/Anie.199506761  0.462
1995 Hansen KB, Finney NS, Jacobsen EN. Carbenoidübertragung auf Imine: eine neue asymmetrische katalytische Synthese von Aziridinen Angewandte Chemie. 107: 750-752. DOI: 10.1002/Ange.19951070626  0.377
1994 Jacobsen EN, Finney NS. Synthetic and biological catalysts in chemical synthesis: how to assess practical utility. Chemistry & Biology. 1: 85-90. PMID 9383375 DOI: 10.1016/1074-5521(94)90045-0  0.528
1994 Brandes BD, Jacobsen EN. Highly Enantioselective, Catalytic Epoxidation of Trisubstituted Olefins Journal of Organic Chemistry. 59: 4378-4380. DOI: 10.1021/Jo00095A009  0.526
1994 Larrow JF, Jacobsen EN, Gao Y, Hong Y, Nie X, Zepp CM. A Practical Method for the Large-Scale Preparation of [N,N'-Bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediaminato(2-)]manganese(III) chloride, a Highly Enantioselective Epoxidation Catalyst The Journal of Organic Chemistry. 59: 1939-1942. DOI: 10.1021/Jo00086A062  0.41
1994 Palucki M, Pospisil PJ, Zhang W, Jacobsen EN. Highly Enantioselective, Low-Temperature Epoxidation of Styrene Journal of the American Chemical Society. 116: 9333-9334. DOI: 10.1021/Ja00099A062  0.316
1994 Chang S, Galvin JM, Jacobsen EN. Effect of Chiral Quaternary Ammonium Salts on (salen)Mn-Catalyzed Epoxidation of cis-Olefins. A Highly Enantioselective, Catalytic Route to Trans-Epoxides Journal of the American Chemical Society. 116: 6937-6938. DOI: 10.1021/Ja00094A059  0.605
1994 Zhang W, Lee NH, Jacobsen EN. Nonstereospecific Mechanisms in Asymmetric Addition to Alkenes Result in Enantiodifferentiation after the First Irreversible Step Journal of the American Chemical Society. 116: 425-426. DOI: 10.1021/Ja00080A070  0.422
1994 Chang S, Heid RM, Jacobsen EN. Enantioselective epoxidation of cyclic 1,3-dienes catalyzed by a sterically and electronically optimized (salen)Mn complex Tetrahedron Letters. 35: 669-672. DOI: 10.1016/S0040-4039(00)75786-8  0.611
1994 Jacobsen EN, Deng L, Furukawa Y, Martínez LE. Enantioselective catalytic epoxidation of cinnamate esters Tetrahedron. 50: 4323-4334. DOI: 10.1016/S0040-4020(01)89369-8  0.637
1993 Chang S, Lee NH, Jacobsen EN. Regio- and enantioselective catalytic epoxidation of conjugated polyenes. Formal synthesis of LTA4 methyl ester Journal of Organic Chemistry. 58: 6939-6941. DOI: 10.1021/Jo00077A001  0.631
1993 Li Z, Conser KR, Jacobsen EN. Asymmetric alkene aziridination with readily available chiral diimine-based catalysts Journal of the American Chemical Society. 115: 5326-5327. DOI: 10.1021/Ja00065A067  0.524
1993 Allain EJ, Hager LP, Deng L, Jacobsen EN. Highly enantioselective epoxidation of disubstituted alkenes with hydrogen peroxide catalyzed by chloroperoxidase Journal of the American Chemical Society. 115: 4415-4416. DOI: 10.1021/Ja00063A091  0.568
1993 Fields LB, Jacobsen EN. Synthesis and characterization of chiral bimetallic complexes bearing hard and soft Lewis acidic sites Tetrahedron: Asymmetry. 4: 2229-2240. DOI: 10.1016/S0957-4166(00)80073-7  0.39
1992 Deng L, Jacobsen EN. A practical, highly enantioselective synthesis of the taxol side chain via asymmetric catalysis. Journal of Organic Chemistry. 57: 4320-4323. DOI: 10.1021/Jo00041A054  0.538
1992 Pospisil PJ, Wilson SR, Jacobsen EN. A substoichiometric pyridine-lithium enolate complex: solution and x-ray data and implications for catalysis in the aldol reaction Journal of the American Chemical Society. 114: 7585-7587. DOI: 10.1021/Ja00045A054  0.342
1992 Palucki M, Hanson P, Jacobsen EN. Asymmetric oxidation of sulfides with H2O2 catalyzed by (salen)Mn(III) complexes Tetrahedron Letters. 33: 7111-7114. DOI: 10.1016/S0040-4039(00)60849-3  0.441
1991 Zhang W, Jacobsen EN. Asymmetric olefin epoxidation with sodium hypochlorite catalyzed by easily prepared chiral manganese(III) salen complexes The Journal of Organic Chemistry. 56: 2296-2298. DOI: 10.1021/Jo00007A012  0.446
1991 Jacobsen EN, Zhang W, Muci AR, Ecker JR, Deng L. Highly enantioselective epoxidation catalysts derived from 1,2-diaminocyclohexane Journal of the American Chemical Society. 113: 7063-7064. DOI: 10.1021/Ja00018A068  0.609
1991 Jacobsen EN, Zhang W, Guler ML. Electronic tuning of asymmetric catalysts Journal of the American Chemical Society. 113: 6703-6704. DOI: 10.1021/Ja00017A069  0.418
1991 Lee NH, Muci AR, Jacobsen EN. Enantiomerically Pure Epoxychromans via Asymmetric Catalysis Tetrahedron Letters. 32: 5055-5058. DOI: 10.1016/S0040-4039(00)93426-9  0.443
1991 Zhang W, Jacobsen EN. Preparation of trans-1,2-diamino-1,2-dimethylcyclohexane via highly stereoselective olefin oxidation by dinitrogen tetroxide Tetrahedron Letters. 32: 1711-1714. DOI: 10.1016/S0040-4039(00)74310-3  0.465
1991 Lee NH, Jacobsen EN. Enantioselective epoxidation of conjugated dienes and enynes. Trans-epoxides from cis-olefins Tetrahedron Letters. 32: 6533-6536. DOI: 10.1016/0040-4039(91)80212-O  0.459
1990 Zhang W, Loebach JL, Wilson SR, Jacobsen EN. Enantioselective epoxidation of unfunctionalized olefins catalyzed by salen manganese complexes Journal of the American Chemical Society. 112: 2801-2803. DOI: 10.1021/Ja00163A052  0.467
1989 Svendsen JS, Marko I, Jacobsen EN, Rao CP, Bott S, Sharpless KB. The structure of osmium tetraoxide-cinchona alkaloid complexes The Journal of Organic Chemistry. 54: 2263-2264. DOI: 10.1021/Jo00271A002  0.601
1989 Wai JSM, Marko I, Svendsen JS, Finn MG, Jacobsen EN, Sharpless KB. A mechanistic insight leads to a greatly improved osmium-catalyzed asymmetric dihydroxylation process Journal of the American Chemical Society. 111: 1123-1125. DOI: 10.1021/Ja00185A050  0.714
1989 Jacobsen EN, Marko I, France MB, Svendsen JS, Sharpless KB. Kinetic role of the alkaloid ligands in asymmetric catalytic dihydroxylation Journal of the American Chemical Society. 111: 737-739. DOI: 10.1021/Ja00184A055  0.68
1988 Jacobsen EN, Goldberg KI, Bergman RG. Rapid, reversible intramolecular carbon-hydrogen oxidative addition and hydrogen exchange in a heterodinuclear "early-late" transition metal complex Journal of the American Chemical Society. 110: 3706-3707. DOI: 10.1021/Ja00219A081  0.63
1988 Jacobsen EN, Marko I, Mungall WS, Schroeder G, Sharpless KB. Asymmetric dihydroxylation via ligand-accelerated catalysis Journal of the American Chemical Society. 110: 1968-1970. DOI: 10.1021/Ja00214A053  0.634
1986 Jacobsen EN, Trost MK, Bergman RG. Synthesis of organometallic heterodinuclear .mu.-oxo complexes by extrusion of alkenes from zirconium/tungsten oxaalkyl complexes Journal of the American Chemical Society. 108: 8092-8094. DOI: 10.1021/Ja00285A038  0.479
1985 Jacobsen EN, Bergman RG. Synthesis and chemistry of a bridging vinylidenedicobalt complex. Evidence for a nonchain radical mechanism in its reaction with metal hydrides to give heteronuclear clusters Journal of the American Chemical Society. 107: 2023-2032. DOI: 10.1021/Ja00293A037  0.471
1985 Jacobsen EN, Totten GE, Wenke G, Karydas AC, Rhodes YE. Steric effects on the titanium tetrachloride promoted dimerization of silyl ketene acetals Synthetic Communications. 15: 301-306. DOI: 10.1002/Chin.198543102  0.753
1985 JACOBSEN EN, BERGMAN RG. ChemInform Abstract: SYNTHESIS AND CHEMISTRY OF A BRIDGING VINYLIDENEDICOBALT COMPLEX. EVIDENCE FOR A NONCHAIN RADICAL MECHANISM IN ITS REACTION WITH METAL HYDRIDES TO GIV HETERONUCLEAR CLUSTERS Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198533307  0.434
1984 Jacobsen EN, Bergman RG. Synthesis, crystal and molecular structure, and reactions of the bridging vinylidenedicobalt complex (.mu.-CCH2)(CpCoCO)2. Reaction with molybdenum hydrides to give a heteronuclear cluster complex Organometallics. 3: 329-331. DOI: 10.1021/Om00080A031  0.441
1983 Wenke WG, Jacobsen EN, Totten GE, Karydas AC, Rhodes YE. Silyl ketene acetal chemistry: Steric limitations in lewis acid-promoted addition of ketones Synthetic Communications. 13: 449-458. DOI: 10.1080/00397918308081822  0.822
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