Alanna Schepartz - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
protein–protein and protein–DNA interactions
Website:
http://www.chem.yale.edu/faculty/schepartz.html

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ad O, Hoffman KS, Cairns AG, Featherston AL, Miller SJ, Söll D, Schepartz A. Translation of Diverse Aramid- and 1,3-Dicarbonyl-peptides by Wild Type Ribosomes . Acs Central Science. 5: 1289-1294. PMID 31403077 DOI: 10.1021/acscentsci.9b00460  0.44
2019 Erdmann RS, Baguley SW, Richens JH, Wissner RF, Xi Z, Allgeyer ES, Zhong S, Thompson AD, Lowe N, Butler R, Bewersdorf J, Rothman JE, St Johnston D, Schepartz A, Toomre D. Labeling Strategies Matter for Super-Resolution Microscopy: A Comparison between HaloTags and SNAP-tags. Cell Chemical Biology. PMID 30745239 DOI: 10.1016/j.chembiol.2019.01.003  0.44
2019 Steinauer A, LaRochelle JR, Knox SL, Wissner RF, Berry S, Schepartz A. HOPS-dependent endosomal fusion required for efficient cytosolic delivery of therapeutic peptides and small proteins. Proceedings of the National Academy of Sciences of the United States of America. 116: 512-521. PMID 30610181 DOI: 10.1073/pnas.1812044116  0.76
2018 Wissner RF, Steinauer A, Knox SL, Thompson AD, Schepartz A. Fluorescence Correlation Spectroscopy Reveals Efficient Cytosolic Delivery of Protein Cargo by Cell-Permeant Miniature Proteins. Acs Central Science. 4: 1379-1393. PMID 30410976 DOI: 10.1021/acscentsci.8b00446  0.44
2018 Tjin CC, Wissner RF, Jamali H, Schepartz A, Ellman JA. Synthesis and Biological Evaluation of an Indazole-Based Selective Protein Arginine Deiminase 4 (PAD4) Inhibitor. Acs Medicinal Chemistry Letters. 9: 1013-1018. PMID 30344909 DOI: 10.1021/acsmedchemlett.8b00283  0.44
2018 Sinclair JKL, Walker AS, Doerner AE, Schepartz A. Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR. Cell Chemical Biology. PMID 29731426 DOI: 10.1016/j.chembiol.2018.04.005  0.64
2018 Wadzinski TJ, Steinauer A, Hie L, Pelletier G, Schepartz A, Miller SJ. Rapid phenolic O-glycosylation of small molecules and complex unprotected peptides in aqueous solvent. Nature Chemistry. PMID 29713033 DOI: 10.1038/s41557-018-0041-8  0.44
2017 Schepartz A, Bergman R, Grubbs RH. Ronald Breslow (1931-2017). Angewandte Chemie (International Ed. in English). PMID 29235715 DOI: 10.1002/anie.201711641  0.48
2017 Quach K, LaRochelle J, Li XH, Rhoades E, Schepartz A. Unique arginine array improves cytosolic localization of hydrocarbon-stapled peptides. Bioorganic & Medicinal Chemistry. PMID 29150077 DOI: 10.1016/j.bmc.2017.11.008  0.4
2017 Erdmann RS, Toomre D, Schepartz A. STED Imaging of Golgi Dynamics with Cer-SiR: A Two-Component, Photostable, High-Density Lipid Probe for Live Cells. Methods in Molecular Biology (Clifton, N.J.). 1663: 65-78. PMID 28924659 DOI: 10.1007/978-1-4939-7265-4_6  0.32
2017 Thompson AD, Bewersdorf J, Toomre D, Schepartz A. HIDE Probes: A New Toolkit for Visualizing Organelle Dynamics, Longer and at Super-Resolution. Biochemistry. PMID 28792749 DOI: 10.1021/acs.biochem.7b00545  0.32
2017 Schepartz A, Thompson AD, Omar MH, Rivera-Molina F, Xi Z, Koleske AJ, Toomre DK. Long-Term Live-Cell STED Nanoscopy of Primary and Cultured Cells with the Plasma Membrane HIDE Probe DiI-SiR. Angewandte Chemie (International Ed. in English). PMID 28679029 DOI: 10.1002/anie.201704783  0.32
2017 Takakura H, Zhang Y, Erdmann RS, Thompson AD, Lin Y, McNellis B, Rivera-Molina F, Uno SN, Kamiya M, Urano Y, Rothman JE, Bewersdorf J, Schepartz A, Toomre D. Long time-lapse nanoscopy with spontaneously blinking membrane probes. Nature Biotechnology. 35: 773-780. PMID 28671662 DOI: 10.1038/nbt.3876  0.32
2017 Bottanelli F, Kilian N, Ernst AM, Rivera-Molina F, Schroeder LK, Kromann EB, Lessard MD, Erdmann RS, Schepartz A, Baddeley D, Bewersdorf J, Toomre D, Rothman JE. A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi. Molecular Biology of the Cell. 28: 1676-1687. PMID 28428254 DOI: 10.1091/mbc.E16-12-0863  0.32
2016 Walker AS, Rablen PX, Schepartz A. Rotamer-Restricted Fluorogenicity of the Bis-Arsenical ReAsH. Journal of the American Chemical Society. PMID 27163487 DOI: 10.1021/jacs.6b03422  0.4
2016 Wang PS, Schepartz A. β-Peptide bundles: Design. Build. Analyze. Biosynthesize. Chemical Communications (Cambridge, England). PMID 27146019 DOI: 10.1039/c6cc01546h  1
2016 Melo Czekster C, Robertson WE, Walker AS, Söll D, Schepartz A. In Vivo Biosynthesis of a β-Amino Acid-Containing Protein. Journal of the American Chemical Society. PMID 27086674 DOI: 10.1021/jacs.6b01023  0.4
2016 Bottanelli F, Kromann EB, Allgeyer ES, Erdmann RS, Wood Baguley S, Sirinakis G, Schepartz A, Baddeley D, Toomre DK, Rothman JE, Bewersdorf J. Two-colour live-cell nanoscale imaging of intracellular targets. Nature Communications. 7: 10778. PMID 26940217 DOI: 10.1038/ncomms10778  0.32
2016 Pelletier G, Zwicker A, Allen CL, Schepartz A, Miller SJ. Aqueous Glycosylation of Unprotected Sucrose Employing Glycosyl Fluorides in the Presence of Calcium Ion and Trimethylamine. Journal of the American Chemical Society. PMID 26859619 DOI: 10.1021/jacs.5b13384  1
2015 Li M, Tao Y, Shu Y, LaRochelle JR, Steinauer A, Thompson D, Schepartz A, Chen ZY, Liu DR. Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo. Journal of the American Chemical Society. PMID 26465072 DOI: 10.1021/jacs.5b05694  1
2015 Melicher MS, Walker AS, Shen J, Miller SJ, Schepartz A. Improved Carbohydrate Recognition in Water with an Electrostatically Enhanced β-Peptide Bundle. Organic Letters. PMID 26376076 DOI: 10.1021/acs.orglett.5b02187  1
2015 Doerner A, Scheck R, Schepartz A. Growth Factor Identity Is Encoded by Discrete Coiled-Coil Rotamers in the EGFR Juxtamembrane Region. Chemistry & Biology. 22: 776-84. PMID 26091170 DOI: 10.1016/j.chembiol.2015.05.008  1
2015 Lowder MA, Doerner AE, Schepartz A. Structural Differences between Wild-Type and Double Mutant EGFR Modulated by Third-Generation Kinase Inhibitors. Journal of the American Chemical Society. 137: 6456-9. PMID 25973741 DOI: 10.1021/jacs.5b02326  1
2015 Miller JP, Melicher MS, Schepartz A. Correction to "Positive allostery in metal ion binding by a cooperatively folded β-peptide bundle". Journal of the American Chemical Society. 137: 3994. PMID 25774681 DOI: 10.1021/jacs.5b02565  1
2015 LaRochelle JR, Cobb GB, Steinauer A, Rhoades E, Schepartz A. Fluorescence correlation spectroscopy reveals highly efficient cytosolic delivery of certain penta-arg proteins and stapled peptides. Journal of the American Chemical Society. 137: 2536-41. PMID 25679876 DOI: 10.1021/ja510391n  1
2014 Miller JP, Melicher MS, Schepartz A. Positive allostery in metal ion binding by a cooperatively folded β-peptide bundle. Journal of the American Chemical Society. 136: 14726-9. PMID 25290247 DOI: 10.1021/ja508872q  1
2014 Sinclair JK, Schepartz A. Influence of macrocyclization on allosteric, juxtamembrane-derived, stapled peptide inhibitors of the epidermal growth factor receptor (EGFR). Organic Letters. 16: 4916-9. PMID 25207804 DOI: 10.1021/ol502426b  1
2014 Erdmann RS, Takakura H, Thompson AD, Rivera-Molina F, Allgeyer ES, Bewersdorf J, Toomre D, Schepartz A. Super-resolution imaging of the Golgi in live cells with a bioorthogonal ceramide probe. Angewandte Chemie (International Ed. in English). 53: 10242-6. PMID 25081303 DOI: 10.1002/anie.201403349  1
2014 Sinclair JK, Denton EV, Schepartz A. Inhibiting epidermal growth factor receptor at a distance. Journal of the American Chemical Society. 136: 11232-5. PMID 25075632 DOI: 10.1021/ja504076t  1
2014 Alexander SC, Schepartz A. Interactions of AsCy3 with cysteine-rich peptides. Organic Letters. 16: 3824-7. PMID 24999741 DOI: 10.1021/ol501721j  1
2014 Wang PS, Nguyen JB, Schepartz A. Design and high-resolution structure of a β³-peptide bundle catalyst. Journal of the American Chemical Society. 136: 6810-3. PMID 24802883 DOI: 10.1021/ja5013849  1
2013 Hobert EM, Doerner AE, Walker AS, Schepartz A. Effective molarity redux: Proximity as a guiding force in chemistry and biology. Israel Journal of Chemistry. 53: 567-576. PMID 25418998 DOI: 10.1002/ijch.201300063  1
2013 Holub JM, Larochelle JR, Appelbaum JS, Schepartz A. Improved assays for determining the cytosolic access of peptides, proteins, and their mimetics. Biochemistry. 52: 9036-46. PMID 24256505 DOI: 10.1021/bi401069g  1
2013 Gould ND, Liana Allen C, Nam BC, Schepartz A, Miller SJ. Combined Lewis acid and Brønsted acid-mediated reactivity of glycosyl trichloroacetimidate donors. Carbohydrate Research. 382: 36-42. PMID 24177201 DOI: 10.1016/j.carres.2013.09.011  1
2013 Denton EV, Craig CJ, Pongratz RL, Appelbaum JS, Doerner AE, Narayanan A, Shulman GI, Cline GW, Schepartz A. A β-peptide agonist of the GLP-1 receptor, a class B GPCR. Organic Letters. 15: 5318-21. PMID 24087900 DOI: 10.1021/ol402568j  1
2013 Melicher MS, Chu J, Walker AS, Miller SJ, Baxter RH, Schepartz A. A β-boronopeptide bundle of known structure as a vehicle for polyol recognition. Organic Letters. 15: 5048-51. PMID 24032486 DOI: 10.1021/ol402381n  1
2013 Molski MA, Goodman JL, Chou FC, Baker D, Das R, Schepartz A. Remodeling a β-peptide bundle Chemical Science. 4: 319-324. DOI: 10.1039/c2sc21117c  1
2013 Schepartz A, Zimmerman SC. Supramolecular chemistry for biology, materials and medicine Israel Journal of Chemistry. 53: 495-496. DOI: 10.1002/ijch.201310007  1
2012 Appelbaum JS, LaRochelle JR, Smith BA, Balkin DM, Holub JM, Schepartz A. Arginine topology controls escape of minimally cationic proteins from early endosomes to the cytoplasm. Chemistry & Biology. 19: 819-30. PMID 22840770 DOI: 10.1016/j.chembiol.2012.05.022  1
2012 Wang PS, Craig CJ, Schepartz A. Relationship between side-chain branching and stoichiometry in β(3)-peptide bundles. Tetrahedron. 68: 4342-4345. PMID 22822272 DOI: 10.1016/j.tet.2012.03.079  1
2012 Scheck RA, Lowder MA, Appelbaum JS, Schepartz A. Bipartite tetracysteine display reveals allosteric control of ligand-specific EGFR activation. Acs Chemical Biology. 7: 1367-76. PMID 22667988 DOI: 10.1021/cb300216f  1
2012 Hobert EM, Schepartz A. Rewiring kinase specificity with a synthetic adaptor protein. Journal of the American Chemical Society. 134: 3976-8. PMID 22352870 DOI: 10.1021/ja211089v  1
2011 Schepartz A, Gonzalez RL. Molecular imaging: sine labore nihil. Current Opinion in Chemical Biology. 15: 749-51. PMID 22104180 DOI: 10.1016/j.cbpa.2011.11.001  1
2011 Lowder MA, Appelbaum JS, Hobert EM, Schepartz A. Visualizing protein partnerships in living cells and organisms. Current Opinion in Chemical Biology. 15: 781-8. PMID 22104179 DOI: 10.1016/j.cbpa.2011.10.024  1
2011 Scheck RA, Schepartz A. Surveying protein structure and function using bis-arsenical small molecules. Accounts of Chemical Research. 44: 654-65. PMID 21766813 DOI: 10.1021/ar2001028  1
2011 Craig CJ, Goodman JL, Schepartz A. Enhancing β3 -peptide bundle stability by design. Chembiochem : a European Journal of Chemical Biology. 12: 1035-8. PMID 21455925 DOI: 10.1002/cbic.201000753  1
2010 Ray-Saha S, Schepartz A. Visualizing tyrosine kinase activity with bipartite tetracysteine display. Chembiochem : a European Journal of Chemical Biology. 11: 2089-91. PMID 20848632 DOI: 10.1002/cbic.201000234  1
2010 Dexter RJ, Schepartz A. Direct visualization of protein association in living cells with complex-edited electron microscopy. Angewandte Chemie (International Ed. in English). 49: 7952-4. PMID 20845344 DOI: 10.1002/anie.201003217  1
2010 Molski MA, Goodman JL, Craig CJ, Meng H, Kumar K, Schepartz A. Beta-peptide bundles with fluorous cores. Journal of the American Chemical Society. 132: 3658-9. PMID 20196598 DOI: 10.1021/ja910903c  1
2010 Bautista AD, Appelbaum JS, Craig CJ, Michel J, Schepartz A. Bridged beta(3)-peptide inhibitors of p53-hDM2 complexation: correlation between affinity and cell permeability. Journal of the American Chemical Society. 132: 2904-6. PMID 20158215 DOI: 10.1021/ja910715u  1
2009 Goodman JL, Fried DB, Schepartz A. Bipartite tetracysteine display requires site flexibility for ReAsH coordination. Chembiochem : a European Journal of Chemical Biology. 10: 1644-7. PMID 19533719 DOI: 10.1002/cbic.200900207  1
2009 Bautista AD, Stephens OM, Wang L, Domaoal RA, Anderson KS, Schepartz A. Identification of a beta3-peptide HIV fusion inhibitor with improved potency in live cells. Bioorganic & Medicinal Chemistry Letters. 19: 3736-8. PMID 19497744 DOI: 10.1016/j.bmcl.2009.05.032  1
2009 Michel J, Harker EA, Tirado-Rives J, Jorgensen WL, Schepartz A. In Silico Improvement of beta3-peptide inhibitors of p53 x hDM2 and p53 x hDMX. Journal of the American Chemical Society. 131: 6356-7. PMID 19415930 DOI: 10.1021/ja901478e  1
2009 Harker EA, Schepartz A. Cell-permeable beta-peptide inhibitors of p53/hDM2 complexation. Chembiochem : a European Journal of Chemical Biology. 10: 990-3. PMID 19266537 DOI: 10.1002/cbic.200900049  1
2009 Harker EA, Daniels DS, Guarracino DA, Schepartz A. Beta-peptides with improved affinity for hDM2 and hDMX. Bioorganic & Medicinal Chemistry. 17: 2038-46. PMID 19211253 DOI: 10.1016/j.bmc.2009.01.039  1
2009 Halo TL, Appelbaum J, Hobert EM, Balkin DM, Schepartz A. Selective recognition of protein tetraserine motifs with a cell-permeable, pro-fluorescent bis-boronic acid. Journal of the American Chemical Society. 131: 438-9. PMID 19105691 DOI: 10.1021/ja807872s  1
2008 Goodman JL, Molski MA, Qiu J, Schepartz A. Tetrameric beta(3)-peptide bundles. Chembiochem : a European Journal of Chemical Biology. 9: 1576-8. PMID 18528915 DOI: 10.1002/cbic.200800039  1
2008 Smith BA, Daniels DS, Coplin AE, Jordan GE, McGregor LM, Schepartz A. Minimally cationic cell-permeable miniature proteins via alpha-helical arginine display. Journal of the American Chemical Society. 130: 2948-9. PMID 18271592 DOI: 10.1021/ja800074v  1
2008 Petersson EJ, Schepartz A. Toward beta-amino acid proteins: design, synthesis, and characterization of a fifteen kilodalton beta-peptide tetramer. Journal of the American Chemical Society. 130: 821-3. PMID 18166055 DOI: 10.1021/ja077245x  1
2007 Bautista AD, Craig CJ, Harker EA, Schepartz A. Sophistication of foldamer form and function in vitro and in vivo. Current Opinion in Chemical Biology. 11: 685-92. PMID 17988934 DOI: 10.1016/j.cbpa.2007.09.009  1
2007 Goodman JL, Petersson EJ, Daniels DS, Qiu JX, Schepartz A. Biophysical and structural characterization of a robust octameric beta-peptide bundle. Journal of the American Chemical Society. 129: 14746-51. PMID 17985897 DOI: 10.1021/ja0754002  1
2007 Daniels DS, Schepartz A. Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motif. Journal of the American Chemical Society. 129: 14578-9. PMID 17983240 DOI: 10.1021/ja0772445  1
2007 Luedtke NW, Dexter RJ, Fried DB, Schepartz A. Surveying polypeptide and protein domain conformation and association with FlAsH and ReAsH. Nature Chemical Biology. 3: 779-84. PMID 17982447 DOI: 10.1038/nchembio.2007.49  1
2007 Holtzman JH, Woronowicz K, Golemi-Kotra D, Schepartz A. Miniature protein ligands for EVH1 domains: interplay between affinity, specificity, and cell motility. Biochemistry. 46: 13541-53. PMID 17973491 DOI: 10.1021/bi700975f  1
2007 Hodges AM, Schepartz A. Engineering a monomeric miniature protein. Journal of the American Chemical Society. 129: 11024-5. PMID 17705497 DOI: 10.1021/ja074859t  1
2007 Petersson EJ, Craig CJ, Daniels DS, Qiu JX, Schepartz A. Biophysical characterization of a beta-peptide bundle: comparison to natural proteins. Journal of the American Chemical Society. 129: 5344-5. PMID 17425318 DOI: 10.1021/ja070567g  1
2007 Daniels DS, Petersson EJ, Qiu JX, Schepartz A. High-resolution structure of a beta-peptide bundle. Journal of the American Chemical Society. 129: 1532-3. PMID 17283998 DOI: 10.1021/ja068678n  1
2006 Zellefrow CD, Griffiths JS, Saha S, Hodges AM, Goodman JL, Paulk J, Kritzer JA, Schepartz A. Encodable activators of SRC family kinases. Journal of the American Chemical Society. 128: 16506-7. PMID 17177392 DOI: 10.1021/ja0672977  1
2006 Qiu JX, Petersson EJ, Matthews EE, Schepartz A. Toward beta-amino acid proteins: a cooperatively folded beta-peptide quaternary structure. Journal of the American Chemical Society. 128: 11338-9. PMID 16939241 DOI: 10.1021/ja063164+  1
2006 Guarracino DA, Chiang HR, Banks TN, Lear JD, Hodsdon ME, Schepartz A. Relationship between salt-bridge identity and 14-helix stability of beta3-peptides in aqueous buffer. Organic Letters. 8: 807-10. PMID 16494446 DOI: 10.1021/ol0527532  1
2006 Kritzer JA, Zutshi R, Cheah M, Ran FA, Webman R, Wongjirad TM, Schepartz A. Miniature protein inhibitors of the p53-hDM2 interaction. Chembiochem : a European Journal of Chemical Biology. 7: 29-31. PMID 16397877 DOI: 10.1002/cbic.200500324  1
2005 Luedtke NW, Schepartz A. Lanthanide-mediated phosphoester hydrolysis and phosphate elimination from phosphopeptides. Chemical Communications (Cambridge, England). 5426-8. PMID 16261235 DOI: 10.1039/b510123a  1
2005 Kritzer JA, Luedtke NW, Harker EA, Schepartz A. A rapid library screen for tailoring beta-peptide structure and function. Journal of the American Chemical Society. 127: 14584-5. PMID 16231906 DOI: 10.1021/ja055050o  1
2005 Stephens OM, Kim S, Welch BD, Hodsdon ME, Kay MS, Schepartz A. Inhibiting HIV fusion with a beta-peptide foldamer. Journal of the American Chemical Society. 127: 13126-7. PMID 16173723 DOI: 10.1021/ja053444+  1
2005 Yang L, Schepartz A. Relationship between folding and function in a sequence-specific miniature DNA-binding protein. Biochemistry. 44: 7469-78. PMID 15895990 DOI: 10.1021/bi050121h  1
2005 Schneider TL, Mathew RS, Rice KP, Tamaki K, Wood JL, Schepartz A. Increasing the kinase specificity of k252a by protein surface recognition. Organic Letters. 7: 1695-8. PMID 15844883 DOI: 10.1021/ol050179o  1
2005 Volkman HM, Rutledge SE, Schepartz A. Binding mode and transcriptional activation potential of high affinity ligands for the CBP KIX domain. Journal of the American Chemical Society. 127: 4649-58. PMID 15796530 DOI: 10.1021/ja042761y  1
2005 Kritzer JA, Hodsdon ME, Schepartz A. Solution structure of a beta-peptide ligand for hDM2. Journal of the American Chemical Society. 127: 4118-9. PMID 15783163 DOI: 10.1021/ja042933r  1
2005 Gemperli AC, Rutledge SE, Maranda A, Schepartz A. Paralog-selective ligands for bcl-2 proteins. Journal of the American Chemical Society. 127: 1596-7. PMID 15700967 DOI: 10.1021/ja0441211  1
2005 Kritzer JA, Tirado-Rives J, Hart SA, Lear JD, Jorgensen WL, Schepartz A. Relationship between side chain structure and 14-helix stability of beta3-peptides in water. Journal of the American Chemical Society. 127: 167-78. PMID 15631466 DOI: 10.1021/ja0459375  1
2005 Kritzer JA, Stephens OM, Guarracino DA, Reznik SK, Schepartz A. beta-Peptides as inhibitors of protein-protein interactions. Bioorganic & Medicinal Chemistry. 13: 11-6. PMID 15582447 DOI: 10.1016/j.bmc.2004.09.009  1
2004 Kritzer JA, Lear JD, Hodsdon ME, Schepartz A. Helical beta-peptide inhibitors of the p53-hDM2 interaction. Journal of the American Chemical Society. 126: 9468-9. PMID 15291512 DOI: 10.1021/ja031625a  1
2004 Golemi-Kotra D, Mahaffy R, Footer MJ, Holtzman JH, Pollard TD, Theriot JA, Schepartz A. High affinity, paralog-specific recognition of the Mena EVH1 domain by a miniature protein. Journal of the American Chemical Society. 126: 4-5. PMID 14709031 DOI: 10.1021/ja037954k  1
2003 Rutledge SE, Volkman HM, Schepartz A. Molecular recognition of protein surfaces: high affinity ligands for the CBP KIX domain. Journal of the American Chemical Society. 125: 14336-47. PMID 14624582 DOI: 10.1021/ja034508o  1
2003 Hart SA, Bahadoor AB, Matthews EE, Qiu XJ, Schepartz A. Helix macrodipole control of beta 3 peptide 14-helix stability in water. Journal of the American Chemical Society. 125: 4022-3. PMID 12670203 DOI: 10.1021/ja029868a  1
2003 Montclare JK, Schepartz A. Miniature homeodomains: high specificity without an N-terminal arm. Journal of the American Chemical Society. 125: 3416-7. PMID 12643688 DOI: 10.1021/ja028628s  1
2002 Rutledge SE, Chin JW, Schepartz A. A view to a kill: ligands for Bcl-2 family proteins. Current Opinion in Chemical Biology. 6: 479-85. PMID 12133724 DOI: 10.1016/S1367-5931(02)00352-6  1
2002 Kays AR, Schepartz A. Gal4-VP16 and Gal4-AH increase the orientational and axial specificity of TATA box recognition by TATA box binding protein. Biochemistry. 41: 3147-55. PMID 11863454 DOI: 10.1021/bi015817z  1
2001 Chin JW, Schepartz A. Design and Evolution of a Miniature Bcl-2 Binding Protein. Angewandte Chemie (International Ed. in English). 40: 3806-3809. PMID 29712146 DOI: 10.1002/1521-3773(20011015)40:20<3806::AID-ANIE3806>3.0.CO;2-B  1
2001 Chin JW, Schepartz A. Design and Evolution of a Miniature Bcl-2 Binding Protein We thank the HHMI Biopolymer/Keck Foundation Biotechnology Resource Laboratory (Yale University School of Medicine, New Haven, CT) for oligonucleotide and peptide synthesis and amino acid analysis and Professor Jennifer Doudna (Yale University) for use of a Perseptive Voyager-DE (MALDI-TOF) mass spectrometer. We are grateful also to Dr. Junying Yuan and Dr. Alexi Degterev (Harvard Medical School) for a generous gift of Bcl-X(L)-His(6) and Stacey E. Rutledge for helpful comments. This work was supported by the National Institutes of Health. Angewandte Chemie (International Ed. in English). 40: 3806-3809. PMID 11668539 DOI: 10.1002/1521-3773(20011015)40:20<3806::AID-ANIE3806>3.0.CO;2-B  1
2001 Kohler JJ, Schepartz A. Effects of nucleic acids and polyanions on dimer formation and DNA binding by bZIP and bHLHZip transcription factors. Bioorganic & Medicinal Chemistry. 9: 2435-43. PMID 11553485 DOI: 10.1016/S0968-0896(01)00221-8  1
2001 Montclare JK, Sloan LS, Schepartz A. Electrostatic control of half-site spacing preferences by the cyclic AMP response element-binding protein CREB. Nucleic Acids Research. 29: 3311-9. PMID 11504868  1
2001 Chin JW, Schepartz A. Concerted evolution of structure and function in a miniature protein. Journal of the American Chemical Society. 123: 2929-30. PMID 11456999 DOI: 10.1021/ja0056668  1
2001 Chin JW, Grotzfeld RM, Fabian MA, Schepartz A. Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display. Bioorganic & Medicinal Chemistry Letters. 11: 1501-5. PMID 11412969 DOI: 10.1016/S0960-894X(01)00139-1  1
2001 Liu Y, Schepartz A. Kinetic preference for oriented DNA binding by the yeast TATA-binding protein TBP. Biochemistry. 40: 6257-66. PMID 11371187 DOI: 10.1021/bi0019794  1
2001 Schneider TL, Schepartz A. Hepatitis B virus protein pX enhances the monomer assembly pathway of bZIP.DNA complexes. Biochemistry. 40: 2835-43. PMID 11258894 DOI: 10.1021/bi002450+  1
2001 Pflum MK, Schneider TL, Hall D, Schepartz A. Hepatitis B virus X protein activates transcription by bypassing CREB phosphorylation, not by stabilizing bZIP-DNA complexes. Biochemistry. 40: 693-703. PMID 11170386 DOI: 10.1021/bi0011936  1
2001 Kohler JJ, Schepartz A. Kinetic studies of Fos.Jun.DNA complex formation: DNA binding prior to dimerization. Biochemistry. 40: 130-42. PMID 11141063 DOI: 10.1021/bi001881p  1
2000 Kays AR, Schepartz A. Virtually unidirectional binding of TBP to the AdMLP TATA box within the quaternary complex with TFIIA and TFIIB. Chemistry & Biology. 7: 601-10. PMID 11048951 DOI: 10.1016/S1074-5521(00)00009-0  1
1999 Chin JW, Kohler JJ, Schneider TL, Schepartz A. Gene regulation: protein escorts to the transcription ball. Current Biology : Cb. 9: R929-32. PMID 10607579 DOI: 10.1016/S0960-9822(00)80107-4  1
1999 Kohler JJ, Metallo SJ, Schneider TL, Schepartz A. DNA specificity enhanced by sequential binding of protein monomers. Proceedings of the National Academy of Sciences of the United States of America. 96: 11735-9. PMID 10518519 DOI: 10.1073/pnas.96.21.11735  1
1999 Zondlo NJ, Schepartz A. Highly specific DNA recognition by a designed miniature protein [2] Journal of the American Chemical Society. 121: 6938-6939. DOI: 10.1021/ja990968z  1
1998 Tsai FT, Littlefield O, Kosa PF, Cox JM, Schepartz A, Sigler PB. Polarity of transcription on Pol II and archaeal promoters: where is the "one-way sign" and how is it read? Cold Spring Harbor Symposia On Quantitative Biology. 63: 53-61. PMID 10384270  1
1998 Cox JM, Kays AR, Sanchez JF, Schepartz A. Preinitation complex assembly: potentially a bumpy path. Current Opinion in Chemical Biology. 2: 11-7. PMID 9667920  1
1998 Sloan LS, Schepartz A. Sequence determinants of the intrinsic bend in the cyclic AMP response element. Biochemistry. 37: 7113-8. PMID 9585522 DOI: 10.1021/bi972009s  1
1997 Palmer CR, Gegnas LD, Schepartz A. Mechanism of DNA binding enhancement by hepatitis B virus protein pX. Biochemistry. 36: 15349-55. PMID 9398264 DOI: 10.1021/bi972076m  1
1997 Cox JM, Hayward MM, Sanchez JF, Gegnas LD, van der Zee S, Dennis JH, Sigler PB, Schepartz A. Bidirectional binding of the TATA box binding protein to the TATA box. Proceedings of the National Academy of Sciences of the United States of America. 94: 13475-80. PMID 9391050 DOI: 10.1073/pnas.94.25.13475  1
1997 Paolella DN, Liu Y, Fabian MA, Schepartz A. Electrostatic mechanism for DNA bending by bZIP proteins. Biochemistry. 36: 10033-8. PMID 9254598 DOI: 10.1021/bi970515b  1
1997 Metallo SJ, Paolella DN, Schepartz A. The role of a basic amino acid cluster in target site selection and non-specific binding of bZIP peptides to DNA. Nucleic Acids Research. 25: 2967-72. PMID 9224594 DOI: 10.1093/nar/25.15.2967  1
1997 Moses AC, Huang SW, Schepartz A. Inhibition of Rev·RRE complexation by triplex tethered oligonucleotide probes. Bioorganic & Medicinal Chemistry. 5: 1123-9. PMID 9222506 DOI: 10.1016/S0968-0896(97)00048-5  1
1997 Metallo SJ, Schepartz A. Certain bZIP peptides bind DNA sequentially as monomers and dimerize on the DNA. Nature Structural Biology. 4: 115-7. PMID 9033590 DOI: 10.1038/nsb0297-115  1
1997 Moses AC, Schepartz A. Kinetics and mechanism of RNA binding by triplex tethered oligonucleotide probes Journal of the American Chemical Society. 119: 11591-11597. DOI: 10.1021/ja971468d  1
1997 Hoffmann P, Schepartz A. Evidence for induced DNA bending by the yeast zinc cluster protein PUT3 Bioorganic and Medicinal Chemistry Letters. 7: 2049-2054. DOI: 10.1016/S0960-894X(97)00355-7  1
1997 Schepartz A. The physical organic chemistry of transcriptional activation Faseb Journal. 11: A854.  1
1996 Moses AC, Schepartz A. Triplex tethered oligonucleotide probes Journal of the American Chemical Society. 118: 10896-10897. DOI: 10.1021/ja961096t  1
1995 Cox JM, Sloan LS, Schepartz A. Conformation of Tax-response elements in the human T-cell leukemia virus type I promoter. Chemistry & Biology. 2: 819-26. PMID 8807815 DOI: 10.1016/1074-5521(95)90088-8  1
1995 Schepartz A. Nonspecific DNA bending and the specificity of protein-DNA interactions. Science (New York, N.Y.). 269: 989-90. PMID 7638626  1
1995 Baranger AM, Palmer CR, Hamm MK, Giebler HA, Brauweiler A, Nyborg JK, Schepartz A. Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax. Nature. 376: 606-8. PMID 7637812 DOI: 10.1038/376606a0  1
1995 Metallo SJ, Schepartz A. Peptide models of bZIP proteins: Quantitative analysis of DNA affinity and specificity Techniques in Protein Chemistry. 6: 385-391. DOI: 10.1016/S1080-8914(06)80047-5  1
1995 Hamm MK, Schepartz A. Studies on the formation of DNA·protein interfaces: DNA specificity and straightening by CREB Bioorganic and Medicinal Chemistry Letters. 5: 1621-1626. DOI: 10.1016/0960-894X(95)00266-V  1
1995 Hayward MM, Adrian JC, Schepartz A. Convenient syntheses of bifunctional metal chelates Journal of Organic Chemistry. 60: 3924-3927.  1
1995 Palmer CR, Sloan LS, Adrian JC, Cuenoud B, Paolella DN, Schepartz A. DNA bending and binding by metallo-zipper models of bZIP proteins Journal of the American Chemical Society. 117: 8899-8907.  1
1994 Metallo SJ, Schepartz A. Distribution of labor among bZIP segments in the control of DNA affinity and specificity. Chemistry & Biology. 1: 143-51. PMID 9383384 DOI: 10.1016/1074-5521(94)90004-3  1
1994 Paolella DN, Palmer CR, Schepartz A. DNA targets for certain bZIP proteins distinguished by an intrinsic bend. Science (New York, N.Y.). 264: 1130-3. PMID 8178171  1
1994 Han H, Schepartz A, Pellegrini M, Dervan PB. Mapping RNA regions in eukaryotic ribosomes that are accessible to methidiumpropyl-EDTA.Fe(II) and EDTA.Fe(II). Biochemistry. 33: 9831-44. PMID 8060991  1
1994 Richardson PL, Gross ML, Light-Wahl KJ, Smith RD, Schepartz A. A uniquely modified RNA: Introduction of a single RNA cleavage agent into the M1 ribozyme Bioorganic and Medicinal Chemistry Letters. 4: 2133-2138. DOI: 10.1016/S0960-894X(01)80116-5  1
1994 Cload ST, Schepartz A. Selection of structure-specific inhibitors of the HIV Rev-Rev response element complex Journal of the American Chemical Society. 116: 437-442.  1
1993 Cuenoud B, Schepartz A. Design of a metallo-bZIP protein that discriminates between CRE and AP1 target sites: selection against AP1. Proceedings of the National Academy of Sciences of the United States of America. 90: 1154-9. PMID 8433977  1
1993 Cuenoud B, Schepartz A. Altered specificity of DNA-binding proteins with transition metal dimerization domains. Science (New York, N.Y.). 259: 510-3. PMID 8424173  1
1993 Cload ST, Richardson PL, Huang YH, Schepartz A. Kinetic and thermodynamic analysis of RNA binding by tethered oligonucleotide probes: Alternative structures and conformational changes Journal of the American Chemical Society. 115: 5005-5014.  1
1992 Ermácora MR, Delfino JM, Cuenoud B, Schepartz A, Fox RO. Conformation-dependent cleavage of staphylococcal nuclease with a disulfide-linked iron chelate. Proceedings of the National Academy of Sciences of the United States of America. 89: 6383-7. PMID 1631134  1
1992 Cuenoud B, Tarasow TM, Schepartz A. A new strategy for directed protein cleavage Tetrahedron Letters. 33: 895-898. DOI: 10.1016/S0040-4039(00)91569-7  1
1992 Jones MW, Gupta N, Schepartz A, Thorp HH. Binding of alkali-metal cations by self-assembling ionophore complexes of nickel(II) Inorganic Chemistry. 31: 1308-1310.  1
1991 Cuenoud B, Schepartz A. A general scheme for incorporating nonnatural functionality into peptides Tetrahedron Letters. 32: 3325-3328. DOI: 10.1016/S0040-4039(00)92697-2  1
1991 Cuenoud B, Schepartz A. Synthesis of N-α-boc-N-ε-tribenzyl EDTA-L-lysine. An amino acid analogue suitable for solid phase peptide synthesis Tetrahedron. 47: 2535-2542. DOI: 10.1016/S0040-4020(01)81787-7  1
1991 Richardson PL, Schepartz A. Tethered oligonucleotide probes. A strategy for the recognition of structured RNA Journal of the American Chemical Society. 113: 5109-5111.  1
1991 Cload ST, Schepartz A. Polyether tethered oligonucleotide probes Journal of the American Chemical Society. 113: 6324-6326.  1
1989 Schepartz A, McDevitt JP. Self-assembling ionophores Journal of the American Chemical Society. 111: 5976-5977.  1
1987 Schepartz A, Breslow R. Hydrolysis of an amide in a carboxypeptidase model using Co(III) and bifunctional catalysts Journal of the American Chemical Society. 109: 1814-1826.  1
1983 Bank S, Schepartz A, Giammatteo P, Zubieta J. Substituent effect on the electrochemical oxidation of arylmethyl anions. 3. Effect of methyl substitution on diarylmethyl anions Journal of Organic Chemistry. 48: 3458-3464.  1
1955 CRIEP LH, SCHEPARTZ AI, LEVINE MI, TOTTEN RS. Serum electrophoretic pattern in experimental hypersensitivity. The Journal of Allergy. 26: 519-32. PMID 13270990  0.48
1953 CRIEP LH, SCHEPARTZ AI, ENGEL M. Relation of pH of allergenic extracts to storage and skin reactivity. The Journal of Allergy. 24: 158-63. PMID 13044478  0.48
Show low-probability matches.