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Stephen Hanessian - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
chemistry of natural products
Website:
http://osiris.corg.umontreal.ca/cv.shtml
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Year Citation  Score
2020 Reddy Vakiti J, Hanessian S. Total Synthesis and Stereochemical Confirmation of (-)-Olivil, (+)-Cycloolivil, (-)-Alashinols F and G, (+)-Cephafortin A, and Their Congeners: Filling in Biosynthetic Gaps. Organic Letters. 22: 3345-3350. PMID 32293189 DOI: 10.1021/Acs.Orglett.0C00773  0.32
2020 Hocine S, Berger G, Hanessian S. Design and Synthesis of Backbone-Fused, Conformationally Constrained Morpholine-Proline Chimeras. The Journal of Organic Chemistry. PMID 32134267 DOI: 10.1021/Acs.Joc.9B03413.S001  0.35
2020 Bodwell G, Hanessian S. Professor James D. Wuest Canadian Journal of Chemistry. 98. DOI: 10.1139/Cjc-2020-0179  0.532
2019 Garsi JB, Vece V, Sernissi L, Auger-Morin C, Hanessian S, McCracken AN, Selwan E, Ramirez C, Dahal A, Romdhane NB, Finicle BT, Edinger AL. Design, synthesis and anticancer activity of constrained sphingolipid-phenoxazine/phenothiazine hybrid constructs targeting protein phosphatase 2A. Bioorganic & Medicinal Chemistry Letters. PMID 31383588 DOI: 10.1016/J.Bmcl.2019.07.023  0.327
2019 Salinas JC, Seth PP, Hanessian S. Design And Synthesis Of An Azabicyclic Nucleoside Phosphoramidite For Oligonucleotide Antisense Constructs. Nucleosides, Nucleotides & Nucleic Acids. 1-23. PMID 31380707 DOI: 10.1080/15257770.2019.1646916  0.352
2019 Duchamp E, Simard BD, Hanessian S. Reductive Fragmentation of Tetrazoles: Mechanistic Insights and Applications toward the Stereocontrolled Synthesis of 2,6-Polysubstituted Morpholines. Organic Letters. PMID 31240939 DOI: 10.1021/Acs.Orglett.9B01842  0.39
2018 Rico L, Hanessian S. Synthesis of 1',2'-methano-2',3'-dideoxynucleosides as potential antivirals. Bioorganic & Medicinal Chemistry Letters. PMID 30612845 DOI: 10.1016/J.Bmcl.2018.12.054  0.369
2018 Garsi JB, Sernissi L, Vece V, Hanessian S, McCracken AN, Simitian G, Edinger AL. In search of constrained FTY720 and phytosphingosine analogs as dual acting anticancer agents targeting metabolic and epigenetic pathways. European Journal of Medicinal Chemistry. 159: 217-242. PMID 30292898 DOI: 10.1016/J.Ejmech.2018.09.043  0.301
2018 Salinas JC, Yu J, Østergaard M, Seth PP, Hanessian S. Conception and Synthesis of Oxabicyclic Nucleoside Phosphonates as Internucleotidic Phosphate Surrogates in Antisense Oligonucleotide Constructs. Organic Letters. PMID 30146887 DOI: 10.1021/Acs.Orglett.8B02233  0.369
2018 Vece V, Jakkepally S, Hanessian S. Total Synthesis and Absolute Stereochemical Assignment of the Insecticidal Metabolites Yaequinolones J1 and J2. Organic Letters. 20: 4277-4280. PMID 29975546 DOI: 10.1021/Acs.Orglett.8B01701  0.375
2018 Kanazawa H, Saavedra OM, Maianti JP, Young SA, Izquierdo L, Smith TK, Hanessian S, Kondo J. Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside. Chemmedchem. PMID 29766661 DOI: 10.1002/Cmdc.201800166  0.787
2017 Chattopadhyay AK, Hanessian S. Recent Progress in the Chemistry of Daphniphyllum Alkaloids †. Chemical Reviews. PMID 28205435 DOI: 10.1021/Acs.Chemrev.6B00412  0.319
2017 Chénard É, Cusson J, Hanessian S. Catalytic asymmetric Friedel–Crafts synthesis of 1,1′-diaryl-2-substituted 4-pentenes enables stereoselective access to functionalized tetrahydronaphthalenes Canadian Journal of Chemistry. 95: 1323-1331. DOI: 10.1139/Cjc-2017-0393  0.404
2016 St-Pierre G, Hanessian S. Solution and Solid-Phase Stereocontrolled Synthesis of 1,2-cis-Glycopyranosides with Minimally Protected Glycopyranosyl Donors Catalyzed by BF3-N,N-Dimethylformamide Complex. Organic Letters. PMID 27301355 DOI: 10.1021/Acs.Orglett.6B01263  0.358
2016 Chattopadhyay AK, Berger G, Hanessian S. Strategies toward the Total Synthesis of Calyciphylline B-type Alkaloids: A Computational Perspective Aided by DFT Analysis. The Journal of Organic Chemistry. PMID 27251014 DOI: 10.1021/Acs.Joc.6B00638  0.338
2016 Chattopadhyay AK, Menz H, Ly VL, Dorich S, Hanessian S. Synthesis of a Model Tetracyclic Core Structure of Calyciphylline B-Type Alkaloids. The Journal of Organic Chemistry. PMID 26878089 DOI: 10.1021/Acs.Joc.5B02875  0.776
2016 Büschleb M, Dorich S, Hanessian S, Tao D, Schenthal KB, Overman LE. Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms. Angewandte Chemie (International Ed. in English). PMID 26836448 DOI: 10.1002/Anie.201507549  0.784
2016 Chattopadhyay AK, Ly VL, Jakkepally S, Berger G, Hanessian S. Total Synthesis of Isodaphlongamine H: A Possible Biogenetic Conundrum. Angewandte Chemie (International Ed. in English). PMID 26765928 DOI: 10.1002/Anie.201510861  0.793
2016 Giacometti RD, Salinas JC, Østergaard ME, Swayze EE, Seth PP, Hanessian S. Design, synthesis, and duplex-stabilizing properties of conformationally constrained tricyclic analogues of LNA. Organic & Biomolecular Chemistry. PMID 26765794 DOI: 10.1039/C5Ob02576A  0.378
2016 Hanessian S, St-Pierre G, Dafik L, Klegraf E. Stereocontrolled Synthesis of Phenolic α-d-Glycopyranosides Synthesis. 48: 3575-3588. DOI: 10.1055/S-0035-1561461  0.348
2016 Maianti JP, Hanessian S. Structural hybridization of three aminoglycoside antibiotics yields a potent broad-spectrum bactericide that eludes bacterial resistance enzymes Medchemcomm. 7: 170-176. DOI: 10.1039/C5Md00429B  0.787
2016 Büschleb M, Dorich S, Hanessian S, Tao D, Schenthal KB, Overman LE. Strategien für die Synthese von Naturstoffen mit benachbarten stereogenen quartären Kohlenstoffatomen Angewandte Chemie. 128: 4226-4258. DOI: 10.1002/Ange.201507549  0.769
2015 Chattopadhyay AK, Hanessian S. Cyclic enaminones. Part II: applications as versatile intermediates in alkaloid synthesis. Chemical Communications (Cambridge, England). 51: 16450-67. PMID 26490499 DOI: 10.1039/C5Cc05892A  0.38
2015 Chattopadhyay AK, Hanessian S. Cyclic enaminones. Part I: stereocontrolled synthesis using diastereoselective and catalytic asymmetric methods. Chemical Communications (Cambridge, England). 51: 16437-49. PMID 26490402 DOI: 10.1039/C5Cc05891K  0.421
2015 Berger G, Vilchis-Reyes M, Hanessian S. Structural Properties and Stereochemically Distinct Folding Preferences of 4,5-cis and trans-Methano-L-Proline Oligomers: The Shortest Crystalline PPII-Type Helical Proline-Derived Tetramer. Angewandte Chemie (International Ed. in English). 54: 13268-72. PMID 26346999 DOI: 10.1002/Anie.201506208  0.304
2015 Cusson JP, Chénard E, Hanessian S. On the importance of the relative stereochemistry of substituents in the formation of nine-membered lactones by ring-closing metathesis Synthesis (Germany). 47: 1317-1324. DOI: 10.1055/S-0034-1380130  0.373
2015 Grelier G, Chénard E, Büschleb M, Hanessian S. Proximity- and chelation-induced SNAr 1,4-aromatic ortho-substitution of ortho-methoxyphenyl 2-alkyl ketones Synthesis (Germany). 47: 1091-1100. DOI: 10.1055/S-0034-1379992  0.361
2014 Salinas JC, Migawa MT, Merner BL, Hanessian S. Alternative syntheses of (S)-cEt-BNA: a key constrained nucleoside component of bioactive antisense gapmer sequences. The Journal of Organic Chemistry. 79: 11651-60. PMID 25401196 DOI: 10.1021/Jo502320Y  0.786
2014 Hanessian S, Chénard E, Guesné S, Cusson JP. Conception and evolution of stereocontrolled strategies toward functionalized 8-aryloctanoic acids related to the total synthesis of aliskiren. The Journal of Organic Chemistry. 79: 9531-45. PMID 25285791 DOI: 10.1021/Jo5015195  0.407
2014 Focken T, Hanessian S. Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules. Beilstein Journal of Organic Chemistry. 10: 1848-77. PMID 25246946 DOI: 10.3762/Bjoc.10.195  0.413
2014 Maianti JP, Kanazawa H, Dozzo P, Matias RD, Feeney LA, Armstrong ES, Hildebrandt DJ, Kane TR, Gliedt MJ, Goldblum AA, Linsell MS, Aggen JB, Kondo J, Hanessian S. Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs. Acs Chemical Biology. 9: 2067-73. PMID 25019242 DOI: 10.1021/Cb5003416  0.791
2014 Chénard E, Hanessian S. Kinetic diastereomer differentiation in Au(III)- and Bi(III)-catalyzed benzylic arylation: concise and stereocontrolled synthesis of 2-amino-1,1-diarylalkanes. Organic Letters. 16: 2668-71. PMID 24805004 DOI: 10.1021/Ol500902P  0.349
2014 Hanessian S, Chattopadhyay AK. Iminium ion-enamine cascade cyclizations: facile access to structurally diverse azacyclic compounds and natural products. Organic Letters. 16: 232-5. PMID 24341416 DOI: 10.1021/Ol403229Q  0.335
2014 Hanessian S, Mu C. Yb(OTf)3-Mediated Ring Opening of Functionalized Cyclopentane Epoxides with Aniline: Aspects of Regiochemistry and Stereochemistry Heterocycles. 88: 1553. DOI: 10.3987/Com-13-S(S)85  0.324
2014 Dorich S, Del Valle JR, Hanessian S. Synthesis of functionalized octahydroindoles related to daphnyphyllum alkaloids Synlett. 25: 799-804. DOI: 10.1055/S-0033-1340794  0.782
2014 Hanessian S, Saavedra OM, Vilchis-Reyes MA, Maianti JP, Kanazawa H, Dozzo P, Matias RD, Serio A, Kondo J. Synthesis, broad spectrum antibacterial activity, and X-ray co-crystal structure of the decoding bacterial ribosomal A-site with 4′-deoxy-4′-fluoro neomycin analogs Chemical Science. 5: 4621-4632. DOI: 10.1039/C4Sc01626B  0.803
2014 Hanessian S, Saavedra OM, Vilchis-Reyes MA, Llaguno-Rueda AM. Synthesis of 4′-deoxy-4′-fluoro neamine and 4′-deoxy-4′-fluoro 4′-epi neamine Medchemcomm. 5: 1166-1171. DOI: 10.1039/C4Md00072B  0.381
2014 Hanessian S, Dorich S, Kassem S, Menz H, Chattopadhyay AK. Stereocontrolled synthesis of all-syn 3,4-disubstituted l-prolines: Studies of the reductive rearrangement of unactivated tertiary allylic alcohols Tetrahedron. 70: 439-449. DOI: 10.1016/J.Tet.2013.11.040  0.777
2014 Sánchez-Larios E, Giacometti RD, Hanessian S. Application and scope of Schreiber's gold(I)-catalyzed α-pyrone synthesis to ring a aromatic podolactones European Journal of Organic Chemistry. 2014: 5664-5669. DOI: 10.1002/Ejoc.201402803  0.385
2014 Del Valle JR, Therrien E, Hanessian S. Aeruginosins as Thrombin Inhibitors Natural Products in Medicinal Chemistry. 333-364. DOI: 10.1002/9783527676545.ch10  0.585
2013 Hanessian S, Schroeder BR, Merner BL, Chen B, Swayze EE, Seth PP. Synthesis of cis- and trans-α-l-[4.3.0]bicyclo-DNA monomers for antisense technology: methods for the diastereoselective formation of bicyclic nucleosides. The Journal of Organic Chemistry. 78: 9051-63. PMID 23937280 DOI: 10.1021/Jo401166Q  0.79
2013 Hanessian S, Wagger J, Merner BL, Giacometti RD, Ostergaard ME, Swayze EE, Seth PP. A constrained tricyclic nucleic acid analogue of α-L-LNA: investigating the effects of dual conformational restriction on duplex thermal stability. The Journal of Organic Chemistry. 78: 9064-75. PMID 23937256 DOI: 10.1021/Jo401170Y  0.754
2013 Hanessian S, Dorich S, Chattopadhyay AK, Büschleb M. Studies toward the generation of functionalized quaternary carbon centers relying on Wittig and Wittig-Still allylic ether anionic transpositions. The Journal of Organic Chemistry. 78: 8915-21. PMID 23915281 DOI: 10.1021/Jo401488Y  0.786
2013 Hanessian S, Dorich S, Menz H. Concise and stereocontrolled synthesis of the tetracyclic core of daphniglaucin C. Organic Letters. 15: 4134-7. PMID 23889206 DOI: 10.1021/Ol4018112  0.799
2013 Tourigny DS, Fernández IS, Kelley AC, Vakiti RR, Chattopadhyay AK, Dorich S, Hanessian S, Ramakrishnan V. Crystal structure of a bioactive pactamycin analog bound to the 30S ribosomal subunit. Journal of Molecular Biology. 425: 3907-10. PMID 23702293 DOI: 10.1016/J.Jmb.2013.05.004  0.787
2013 Kondo J, Koganei M, Maianti JP, Ly VL, Hanessian S. Crystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sites. Chemmedchem. 8: 733-9. PMID 23436717 DOI: 10.1002/Cmdc.201200579  0.773
2013 Hanessian S, Vakiti RR, Chattopadhyay AK, Dorich S, Lavallée C. Probing functional diversity in pactamycin toward antibiotic, antitumor, and antiprotozoal activity. Bioorganic & Medicinal Chemistry. 21: 1775-86. PMID 23434136 DOI: 10.1016/J.Bmc.2013.01.037  0.779
2013 Kondo J, Koganei M, Maianti JP, Ly VL, Hanessian S. Back Cover: Crystal Structures of a Bioactive 6′-Hydroxy Variant of Sisomicin Bound to the Bacterial and Protozoal Ribosomal Decoding Sites (ChemMedChem 5/2013) Chemmedchem. 8: 864-864. DOI: 10.1002/Cmdc.201390019  0.761
2012 Hanessian S, Vakiti RR, Dorich S, Banerjee S, Deschênes-Simard B. Total synthesis of pactamycin and pactamycate: a detailed account. The Journal of Organic Chemistry. 77: 9458-72. PMID 23083207 DOI: 10.1021/Jo301638Z  0.816
2012 Hanessian S, Schroeder BR, Giacometti RD, Merner BL, Ostergaard M, Swayze EE, Seth PP. Structure-based design of a highly constrained nucleic acid analogue: improved duplex stabilization by restricting sugar pucker and torsion angle γ. Angewandte Chemie (International Ed. in English). 51: 11242-5. PMID 22915274 DOI: 10.1002/Anie.201203680  0.772
2012 Hanessian S. The enterprise of synthesis: from concept to practice. The Journal of Organic Chemistry. 77: 6657-88. PMID 22784216 DOI: 10.1021/Jo300902M  0.337
2012 Hanessian S, Chénard E. A new approach to the synthesis of peptidomimetic renin inhibitors: palladium-catalyzed asymmetric allylation of acyclic alkyl aryl ketones. Organic Letters. 14: 3222-5. PMID 22668074 DOI: 10.1021/Ol301332F  0.411
2012 Hanessian S, Maianti JP, Ly VL, Deschênes-Simard B. Structural and kinetic study of self-assembling macrocyclic dimer natural product aminoglycoside 66-40C and unnatural variants Chemical Science. 3: 249-256. DOI: 10.1039/C1Sc00538C  0.766
2011 Hanessian S, Giguère A, Grzyb J, Maianti JP, Saavedra OM, Aggen JB, Linsell MS, Goldblum AA, Hildebrandt DJ, Kane TR, Dozzo P, Gliedt MJ, Matias RD, Feeney LA, Armstrong ES. Toward Overcoming Staphylococcus aureus Aminoglycoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue. Acs Medicinal Chemistry Letters. 2: 924-8. PMID 24900282 DOI: 10.1021/Ml200202Y  0.788
2011 Hanessian S, Maianti JP, Matias RD, Feeney LA, Armstrong ES. Hybrid aminoglycoside antibiotics via Tsuji palladium-catalyzed allylic deoxygenation. Organic Letters. 13: 6476-9. PMID 22085292 DOI: 10.1021/Ol2027703  0.795
2011 Hanessian S, Vakiti RR, Dorich S, Banerjee S, Lecomte F, DelValle JR, Zhang J, Deschênes-Simard B. Total synthesis of pactamycin. Angewandte Chemie (International Ed. in English). 50: 3497-500. PMID 21370372 DOI: 10.1002/Anie.201008079  0.809
2011 Hanessian S, Soma U, Dorich S, Deschênes-Simard B. Total synthesis of (+)-ent-cyclizidine: absolute configurational confirmation of antibiotic M146791. Organic Letters. 13: 1048-51. PMID 21271743 DOI: 10.1021/Ol103094J  0.82
2011 Hanessian S, Stoffman E, Mi X, Renton P. Applications of organocatalytic asymmetric synthesis to drug prototypes--dual action and selective inhibitors of n-nitric oxide synthase with activity against the 5-HT1D/1B subreceptors. Organic Letters. 13: 840-3. PMID 21271688 DOI: 10.1021/Ol102795G  0.359
2011 Hanessian S, Focken T, Oza R. Lewis-acid catalyzed formation of dihydropyrans Tetrahedron. 67: 9870-9884. DOI: 10.1016/J.Tet.2011.09.069  0.403
2011 Hanessian S, Vakiti RR, Dorich S, Banerjee S, Lecomte F, DelValle JR, Zhang J, Deschênes-Simard B. Cover Picture: Total Synthesis of Pactamycin (Angew. Chem. Int. Ed. 15/2011) Angewandte Chemie International Edition. 50: 3325-3325. DOI: 10.1002/Anie.201101592  0.797
2011 Hanessian S, Vakiti RR, Dorich S, Banerjee S, Lecomte F, DelValle JR, Zhang J, Deschênes-Simard B. Titelbild: Total Synthesis of Pactamycin (Angew. Chem. 15/2011) Angewandte Chemie. 123: 3383-3383. DOI: 10.1002/Ange.201101592  0.81
2010 Hanessian S, Auzzas L, Larsson A, Zhang J, Giannini G, Gallo G, Ciacci A, Cabri W. Vorinostat-like molecules as structural, stereochemical, and pharmacological tools. Acs Medicinal Chemistry Letters. 1: 70-4. PMID 24900179 DOI: 10.1021/Ml100028G  0.581
2010 Auzzas L, Larsson A, Matera R, Baraldi A, Deschênes-Simard B, Giannini G, Cabri W, Battistuzzi G, Gallo G, Ciacci A, Vesci L, Pisano C, Hanessian S. Non-natural macrocyclic inhibitors of histone deacetylases: design, synthesis, and activity. Journal of Medicinal Chemistry. 53: 8387-99. PMID 21073160 DOI: 10.1021/Jm101092U  0.596
2010 Hanessian S, Larsson A, Fex T, Knecht W, Blomberg N. Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa. Bioorganic & Medicinal Chemistry Letters. 20: 6925-8. PMID 21035339 DOI: 10.1016/J.Bmcl.2010.09.141  0.333
2010 Hanessian S, Pachamuthu K, Szychowski J, Giguère A, Swayze EE, Migawa MT, François B, Kondo J, Westhof E. Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: a synergistic hydrophobic effect against resistant bacteria. Bioorganic & Medicinal Chemistry Letters. 20: 7097-101. PMID 20970332 DOI: 10.1016/J.Bmcl.2010.09.084  0.342
2010 Hanessian S, Focken T, Mi X, Oza R, Chen B, Ritson D, Beaudegnies R. Total synthesis of (+)-ambruticin S: probing the pharmacophoric subunit. The Journal of Organic Chemistry. 75: 5601-18. PMID 20704433 DOI: 10.1021/Jo100956V  0.427
2010 Hanessian S, Focken T, Oza R. Total synthesis of jerangolid A. Organic Letters. 12: 3172-5. PMID 20565089 DOI: 10.1021/Ol101103Q  0.432
2010 Hanessian S, Maji DK, Govindan S, Matera R, Tintelnot-Blomley M. Substrate-controlled and organocatalytic asymmetric synthesis of carbocyclic amino acid dipeptide mimetics. The Journal of Organic Chemistry. 75: 2861-76. PMID 20392053 DOI: 10.1021/Jo100017T  0.355
2010 Hanessian S, Guesné S, Chénard E. Total synthesis of "aliskiren": the first Renin inhibitor in clinical practice for hypertension. Organic Letters. 12: 1816-9. PMID 20235519 DOI: 10.1021/Ol100427V  0.371
2010 Hanessian S, Maianti JP. Biomimetic synthesis and structural refinement of the macrocyclic dimer aminoglycoside 66-40C--the remarkably selective self-condensation of a putative aldehyde intermediate in the submerged culture medium producing sisomicin. Chemical Communications (Cambridge, England). 46: 2013-5. PMID 20221476 DOI: 10.1039/B925668G  0.803
2010 Hanessian S, Deschênes-Simard B, Simard D, Chenel C, Haak E, Bulat V. Proximity-assisted cycloaddition reactions of ω-azido cyanohydrin ethers: Synthesis of diversely functionalized bicyclic tetrazoles Pure and Applied Chemistry. 82: 1761-1771. DOI: 10.1351/Pac-Con-09-08-08  0.358
2010 Hanessian S, Mi X. An organocatalytic approach to enantiopure 2,6-disubstituted tetrahydropyranols Synlett. 761-764. DOI: 10.1055/S-0029-1219354  0.378
2009 Hanessian S, Boyer N, Reddy GJ, Deschênes-Simard B. Total synthesis of oidiodendrolides and related norditerpene dilactones from a common precursor: metabolites CJ-14,445, LL-Z1271gamma, oidiolactones A, B, C, and D, and nagilactone F. Organic Letters. 11: 4640-3. PMID 19778011 DOI: 10.1021/Ol901896C  0.392
2009 Hanessian S, Wang X, Ersmark K, Del Valle JR, Klegraf E. Total synthesis and structural revision of the presumed aeruginosins 205A and B. Organic Letters. 11: 4232-5. PMID 19691354 DOI: 10.1021/Ol901702K  0.668
2009 Hanessian S, Therrien E, Zhang J, Otterlo Wv, Xue Y, Gustafsson D, Nilsson I, Fjellström O. From natural products to achiral drug prototypes: potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs. Bioorganic & Medicinal Chemistry Letters. 19: 5429-32. PMID 19674897 DOI: 10.1016/J.Bmcl.2009.07.107  0.302
2009 Hanessian S, Szychowski J, Maianti JP. Synthesis and comparative antibacterial activity of verdamicin C2 and C2a. A new oxidation of primary allylic azides in dihydro[2H]pyrans. Organic Letters. 11: 429-32. PMID 19072132 DOI: 10.1021/Ol802421D  0.78
2009 Hanessian S. Structure-based synthesis: From natural products to drug prototypes Pure and Applied Chemistry. 81: 1085-1091. DOI: 10.1351/Pac-Con-08-07-12  0.42
2009 Hanessian S, Riber L, Marin J. Diastereoselective synthesis of functionally diverse substituted pipecolic acids Synlett. 71-74. DOI: 10.1055/S-0028-1087477  0.397
2009 Del Valle JR, Wang X, Ersmark K, Hanessian S. β-substituted D-leucines and their relevance in the total synthesis of natural and unnatural aeruginosins Acs Symposium Series. 1009: 443-461. DOI: 10.1021/bk-2009-1009.ch027  0.653
2009 Hanessian S, Deschênes-Simard B, Simard D. Exploring the unique reactivities of heterobicyclic tetrazoles-access to functionally diverse and versatile heterocyclic scaffolds Tetrahedron. 65: 6656-6669. DOI: 10.1016/J.Tet.2009.06.033  0.37
2008 Hanessian S, Auzzas L. The practice of ring constraint in peptidomimetics using bicyclic and polycyclic amino acids. Accounts of Chemical Research. 41: 1241-51. PMID 18646869 DOI: 10.1021/Ar8000052  0.389
2008 Hanessian S, Simard D, Deschênes-Simard B, Chenel C, Haak E. Proximity-assisted cycloaddition reactions--facile Lewis acid-mediated synthesis of diversely functionalized bicyclic tetrazoles. Organic Letters. 10: 1381-4. PMID 18314995 DOI: 10.1021/Ol703071C  0.386
2008 Hanessian S, Simard D, Bayrakdarian M, Therrien E, Nilsson I, Fjellström O. Design, synthesis, and thrombin-inhibitory activity of pyridin-2-ones as P2/P3 core motifs. Bioorganic & Medicinal Chemistry Letters. 18: 1972-6. PMID 18289852 DOI: 10.1016/J.Bmcl.2008.01.122  0.774
2008 Hanessian S, Auzzas L. Alternative and expedient asymmetric syntheses of L-(+)-noviose. Organic Letters. 10: 261-4. PMID 18081305 DOI: 10.1021/Ol702655C  0.332
2008 Ersmark K, Del Valle JR, Hanessian S. Chemistry and biology of the aeruginosin family of serine protease inhibitors. Angewandte Chemie (International Ed. in English). 47: 1202-23. PMID 18076006 DOI: 10.1002/Anie.200605219  0.667
2008 Hanessian S, Vinci V, Fettis K, Maris T, Viet MT. Self-assembly of noncyclic bis-D- and L-tripeptides into higher order tubular constructs: design, synthesis, and X-ray crystal superstructure. The Journal of Organic Chemistry. 73: 1181-91. PMID 18062697 DOI: 10.1021/Jo701621C  0.34
2008 Hanessian S, Hocquelet C, Jankowski CK. Synthesis of aminocyclodextrin carboxylic acids Synlett. 715-719. DOI: 10.1055/S-2008-1042803  0.364
2007 Hanessian S, Auzzas L, Giannini G, Marzi M, Cabri W, Barbarino M, Vesci L, Pisano C. Omega-alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: a study of chain-length and stereochemical dependence. Bioorganic & Medicinal Chemistry Letters. 17: 6261-5. PMID 17892933 DOI: 10.1016/J.Bmcl.2007.09.014  0.598
2007 Kondo J, Pachamuthu K, François B, Szychowski J, Hanessian S, Westhof E. Crystal structure of the bacterial ribosomal decoding site complexed with a synthetic doubly functionalized paromomycin derivative: a new specific binding mode to an a-minor motif enhances in vitro antibacterial activity. Chemmedchem. 2: 1631-8. PMID 17722211 DOI: 10.1002/Cmdc.200700113  0.352
2007 Loiseleur O, Ritson D, Nina M, Crowley P, Wagner T, Hanessian S. Ring-modified analogues and molecular dynamics studies to probe the requirements for fungicidal activities of malayamycin A and its N-nucleoside variants. The Journal of Organic Chemistry. 72: 6353-63. PMID 17658846 DOI: 10.1021/Jo070520D  0.339
2007 Hanessian S, Szychowski J, Adhikari SS, Vasquez G, Kandasamy P, Swayze EE, Migawa MT, Ranken R, François B, Wirmer-Bartoschek J, Kondo J, Westhof E. Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycin. Journal of Medicinal Chemistry. 50: 2352-69. PMID 17458946 DOI: 10.1021/Jm061200+  0.383
2007 Hanessian S, Ersmark K, Wang X, Del Valle JR, Blomberg N, Xue Y, Fjellström O. Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin. Bioorganic & Medicinal Chemistry Letters. 17: 3480-5. PMID 17428662 DOI: 10.1016/J.Bmcl.2007.03.075  0.668
2007 Hanessian S, Szychowski J, Campos-Reales Pineda NB, Furtos A, Keillor JW. 6-hydroxy to 6'''-amino tethered ring-to-ring macrocyclic aminoglycosides as probes for APH(3')-IIIa kinase. Bioorganic & Medicinal Chemistry Letters. 17: 3221-5. PMID 17400454 DOI: 10.1016/J.Bmcl.2007.03.014  0.338
2007 Hanessian S, Reddy GJ. Total synthesis and stereochemical confirmation of 2,5-diaryl-3,4- dimethyltetrahydrofuran lignans: (+)-Fragransin A2, (+)-galbelgin, (+)-talaumidin, (-)-saucernetin and (-)-verrucosin Synlett. 475-479. DOI: 10.1055/S-2007-968019  0.418
2007 Hanessian S, Adhikari S, Szychowski J, Pachamuthu K, Wang X, Migawa MT, Griffey RH, Swayze EE. Corrigendum to "Probing the ribosomal RNA A-site with functionally diverse analogues of paromomycin-synthesis of ring I mimetics". [Tetrahedron 63 (2007) 827-846] (DOI:10.1016/j.tet.2006.10.079) Tetrahedron. 63: 5329. DOI: 10.1016/J.Tet.2007.03.161  0.351
2007 Hanessian S, Adhikari S, Szychowski J, Pachamuthu K, Wang X, Migawa MT, Griffey RH, Swayze EE. Probing the ribosomal RNA A-site with functionally diverse analogues of paromomycin-synthesis of ring I mimetics Tetrahedron. 63: 827-846. DOI: 10.1016/J.Tet.2006.10.079  0.416
2006 Hanessian S, Ritson DJ. Structure-based organic synthesis of a tricyclic N-malayamycin analogue. The Journal of Organic Chemistry. 71: 9807-17. PMID 17168600 DOI: 10.1021/Jo061904R  0.374
2006 Hanessian S, Giroux S, Larsson A. Efficient allyl to propenyl isomerization in functionally diverse compounds with a thermally modified Grubbs second-generation catalyst. Organic Letters. 8: 5481-4. PMID 17107052 DOI: 10.1021/Ol062167O  0.754
2006 Hanessian S, Reddy GJ, Chahal N. Total synthesis and stereochemical confirmation of manassantin A, B, and B1. Organic Letters. 8: 5477-80. PMID 17107051 DOI: 10.1021/Ol0621710  0.304
2006 Hanessian S, Shao Z, Warrier JS. Optimization of the catalytic asymmetric addition of nitroalkanes to cyclic enones with trans-4,5-methano-L-proline. Organic Letters. 8: 4787-90. PMID 17020303 DOI: 10.1021/Ol0618407  0.352
2006 Hanessian S, Chahal N, Giroux S. Iterative synthesis of deoxypropionate units: the inductor effect in acyclic conformation design. The Journal of Organic Chemistry. 71: 7403-11. PMID 16958535 DOI: 10.1021/Jo061098O  0.761
2006 Hanessian S, Mainetti E, Lecomte F. Synthesis and stereochemical confirmation of the secoiridoid glucosides nudiflosides D and A. Organic Letters. 8: 4047-9. PMID 16928070 DOI: 10.1021/Ol0615230  0.359
2006 Hanessian S, Del Valle JR, Xue Y, Blomberg N. Total synthesis and structural confirmation of chlorodysinosin A. Journal of the American Chemical Society. 128: 10491-5. PMID 16895415 DOI: 10.1021/Ja0625834  0.708
2006 Hanessian S, Vinci V, Auzzas L, Marzi M, Giannini G. Exploring alternative Zn-binding groups in the design of HDAC inhibitors: squaric acid, N-hydroxyurea, and oxazoline analogues of SAHA. Bioorganic & Medicinal Chemistry Letters. 16: 4784-7. PMID 16870438 DOI: 10.1016/J.Bmcl.2006.06.090  0.301
2006 Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M. Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). Journal of Medicinal Chemistry. 49: 4544-67. PMID 16854060 DOI: 10.1021/Jm060154A  0.384
2006 Hanessian S, Gauchet C, Charron G, Marin J, Nakache P. Design and synthesis of diversely substituted azacyclic inhibitors of endothelin converting enzyme. The Journal of Organic Chemistry. 71: 2760-78. PMID 16555831 DOI: 10.1021/Jo052649Y  0.374
2006 Hanessian S, Therrien E, van Otterlo WA, Bayrakdarian M, Nilsson I, Fjellström O, Xue Y. Phenolic P2/P3 core motif as thrombin inhibitors--design, synthesis, and X-ray co-crystal structure. Bioorganic & Medicinal Chemistry Letters. 16: 1032-6. PMID 16290930 DOI: 10.1016/J.Bmcl.2005.10.082  0.768
2006 Hanessian S, Therrien E, Warrier JS, Charron G. Synthetic approaches to polyhydroxy indolizidines and related azabicyclic scaffolds Heterocycles. 70: 461-476. DOI: 10.3987/Com-06-S(W)44  0.368
2006 Hanessian S, Talbot C, Mauduit M, Saravanan P, Gone JR. From amino acids to polycyclic heterocycles-synthesis of enantiopure, functionally diverse isopavines and dihydromethanodibenzoazocines Heterocycles. 67: 205-214. DOI: 10.3987/Com-05-S(T)13  0.385
2006 Loiseleur O, Schneider H, Huang G, Machaalani R, Sellès P, Crowley P, Hanessian S. Synthesis of 1-Cytosinyl-N-malayamycin A Synfacts. 2006: 976-976. DOI: 10.1055/S-2006-949317  0.325
2006 Hanessian S, Giroux S, Mascitti V. The iterative synthesis of acyclic deoxypropionate units and their implication in polyketide-derived natural products Synthesis. 1057-1076. DOI: 10.1055/S-2006-926376  0.748
2006 Hanessian S, Talbot C, Saravanan P. Diastereoselective [3,2]-Stevens and Sommelet-Hauser rearrangements in the dihydromethanodibenzoazocine series Synthesis. 723-734. DOI: 10.1055/S-2006-926314  0.381
2006 Loiseleur O, Schneider H, Huang G, Machaalani R, Sellès P, Crowley P, Hanessian S. A scalable synthesis of 1-cytosinyl-N-malayamycin A: A potent fungicide Organic Process Research and Development. 10: 518-524. DOI: 10.1021/Op0600299  0.363
2006 Hanessian S, Del Valle JR, Xue Y, Blomberg N. Total Synthesis and Structural Confirmation of Chlorodysinosin A  [J. Am. Chem. Soc.2006,128, 10491−10495].  Journal of the American Chemical Society. 128: 11727-11728. DOI: 10.1021/Ja069971Q  0.356
2006 Hanessian S, Marcotte S, Machaalani R, Huang G, Pierron J, Loiseleur O. Total synthesis of malayamycin A and analogues Tetrahedron. 62: 5201-5214. DOI: 10.1016/J.Tet.2005.12.066  0.429
2005 Hanessian S, Kothakonda KK. Natural products as scaffolds for chemical diversification: solution-phase parallel synthesis of a series of naringin analogues. Journal of Combinatorial Chemistry. 7: 837-42. PMID 16283793 DOI: 10.1021/Cc0500351  0.351
2005 Hanessian S, Govindan S, Warrier JS. Probing the "additive effect" in the proline and proline hydroxamic acid catalyzed asymmetric addition of nitroalkanes to cyclic enones. Chirality. 17: 540-3. PMID 16189834 DOI: 10.1002/Chir.20201  0.369
2005 Hanessian S, Giroux S, Buffat M. Total synthesis and structural confirmation of (+)-longicin. Organic Letters. 7: 3989-92. PMID 16119949 DOI: 10.1021/Ol051483K  0.786
2005 Hanessian S, Yun H, Hou Y, Tintelnot-Blomley M. Stereoselective synthesis of constrained azacyclic hydroxyethylene isosteres as aspartic protease inhibitors: dipolar cycloaddition and related methodologies toward branched pyrrolidine and pyrrolidinone carboxylic acids. The Journal of Organic Chemistry. 70: 6746-56. PMID 16095294 DOI: 10.1021/Jo050740W  0.367
2005 Hanessian S, Hou Y, Bayrakdarian M, Tintelnot-Blomley M. Stereoselective synthesis of constrained oxacyclic hydroxyethylene isosteres of aspartic protease inhibitors: aldol and Mukaiyama aldol methodologies for branched tetrahydrofuran 2-carboxylic acids. The Journal of Organic Chemistry. 70: 6735-45. PMID 16095293 DOI: 10.1021/Jo050749Y  0.79
2005 Hanessian S, Huang G, Chenel C, Machaalani R, Loiseleur O. Total synthesis of N-malayamycin A and related bicyclic purine and pyrimidine nucleosides. The Journal of Organic Chemistry. 70: 6721-34. PMID 16095292 DOI: 10.1021/Jo050727B  0.383
2005 Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, et al. Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. Journal of Medicinal Chemistry. 48: 5175-90. PMID 16078837 DOI: 10.1021/Jm050142+  0.786
2005 Hanessian S, Kothakonda KK. 3-N,N-Dimethylamino-3-deoxy lincomycin: a structure-based hybrid between lincomycin and the desosamine unit of erythromycin. Bioorganic & Medicinal Chemistry. 13: 5283-8. PMID 15994084 DOI: 10.1016/J.Bmc.2005.05.070  0.373
2005 Hanessian S, Tremblay M, Marzi M, Del Valle JR. Synthetic studies in the intramolecular carbocyclization of N-acyloxyiminium ions. Stereoelectronic and steric implications of nucleophilic alkene, alkyne, and allene tethers. The Journal of Organic Chemistry. 70: 5070-85. PMID 15960507 DOI: 10.1021/Jo050326W  0.764
2005 Hanessian S, Kothakonda KK. Design and synthesis of oxazolidinone ketolide antibiotic segment mimetics Canadian Journal of Chemistry. 83: 801-811. DOI: 10.1139/V05-095  0.342
2005 Hanessian S, Machaalani R. Lewis acid mediated reductive ring opening of 2-methoxyethylidene acetals: A new approach to 2-methoxyethyl (MOE) ethers of cis-diols Synlett. 2437-2440. DOI: 10.1055/S-2005-872686  0.315
2004 Hanessian S, Tremblay M. Tandem functionalization of nonactivated alkenes and alkynes in intramolecular N-acyloxyiminium ion carbocyclization. Synthesis of 6-substituted hydroindole 2-carboxylic acids. Organic Letters. 6: 4683-6. PMID 15575660 DOI: 10.1021/Ol040053B  0.617
2004 Hanessian S, Moitessier N. Sulfonamide-based acyclic and conformationally constrained MMP inhibitors: from computer-assisted design to nanomolar compounds. Current Topics in Medicinal Chemistry. 4: 1269-87. PMID 15320726 DOI: 10.2174/1568026043387953  0.321
2004 Hanessian S, Papeo G, Fettis K, Therrien E, Viet MT. Synthesis of 3 10-helix-inducing constrained analogues of L-proline. The Journal of Organic Chemistry. 69: 4891-9. PMID 15255713 DOI: 10.1021/Jo0401422  0.319
2004 Hanessian S, Mascitti V, Giroux S. Total synthesis of the cytotoxic cyclodepsipeptide (-)-doliculide: the "ester" effect in acyclic 1,3-induction of deoxypropionates. Proceedings of the National Academy of Sciences of the United States of America. 101: 11996-2001. PMID 15210988 DOI: 10.1073/Pnas.0401637101  0.78
2004 Hanessian S, Tremblay M, Petersen JF. The N-acyloxyiminium ion aza-Prins route to octahydroindoles: total synthesis and structural confirmation of the antithrombotic marine natural product oscillarin. Journal of the American Chemical Society. 126: 6064-71. PMID 15137772 DOI: 10.1021/Ja030669G  0.617
2004 Hanessian S, Jnoff E, Bernstein N, Simard M. Bifunctional bis(oxazolines) as potential ligands in catalytic asymmetric reactions Canadian Journal of Chemistry. 82: 306-313. DOI: 10.1139/V03-198  0.357
2004 Hanessian S, Brassard M. Stereoselective synthesis of constrained oxacyclic hydroxyethylene isosteres of aspartyl protease inhibitors. Nitroaldol methodology toward 2,3-substituted tetrahydrofurans Tetrahedron. 60: 7621-7628. DOI: 10.1016/J.Tet.2004.06.060  0.417
2003 Hanessian S, Marcotte S, Machaalani R, Huang G. Total synthesis and structural confirmation of malayamycin A: a novel bicyclic C-nucleoside from Streptomyces malaysiensis. Organic Letters. 5: 4277-80. PMID 14601979 DOI: 10.1021/Ol030095K  0.41
2003 Hanessian S, Yang Y, Giroux S, Mascitti V, Ma J, Raeppel F. Application of conformation design in acyclic stereoselection: total synthesis of borrelidin as the crystalline benzene solvate. Journal of the American Chemical Society. 125: 13784-92. PMID 14599218 DOI: 10.1021/Ja030139K  0.804
2003 Hanessian S, Sailes H, Munro A, Therrien E. Synthesis of diversely functionalized indolizidinones and related bicyclic lactams using intramolecular Grubbs olefin metathesis and Dieckmann condensation. The Journal of Organic Chemistry. 68: 7219-33. PMID 12968870 DOI: 10.1021/Jo030145Z  0.428
2003 Hanessian S, Papeo G, Angiolini M, Fettis K, Beretta M, Munro A. Synthesis of functionally diverse and conformationally constrained polycyclic analogues of proline and prolinol. The Journal of Organic Chemistry. 68: 7204-18. PMID 12968869 DOI: 10.1021/Jo0301447  0.416
2003 Hanessian S, Parthasarathy S, Mauduit M, Payza K. The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. Journal of Medicinal Chemistry. 46: 34-48. PMID 12502358 DOI: 10.1021/Jm020164L  0.349
2003 Hanessian S, Margarita R, Hall A, Johnstone S, Tremblay M, Parlanti L. New and old challenges in total synthesis. From concept to practice Pure and Applied Chemistry. 75: 209-221. DOI: 10.1351/Pac200375020209  0.629
2003 Hanessian S, Bayrakdarian M, Luo X. Total Synthesis of A-315675:  A Potent Inhibitor of Influenza Neuraminidase. [J. Am. Chem. Soc.2002,124(17), 4716−4721]. Journal of the American Chemical Society. 125: 4958-4958. DOI: 10.1021/Ja0334457  0.306
2003 Hanessian S, Wang J, Montgomery D, Stoll V, Stewart KD, Kati W, Maring C, Kempt D, Hutchins C, Laver W. Corrigendum to ‘Design, Synthesis, and Neuraminidase Inhibitory Activity of GS-4071 Analogues that Utilize a Novel Hydrophobic Paradigm’ Bioorganic & Medicinal Chemistry Letters. 13: 1837. DOI: 10.1016/S0960-894X(03)00300-7  0.4
2003 Hanessian S, Sailes H, Therrien E. Synthesis of functionally diverse bicyclic sulfonamides as constrained proline analogues and application to the design of potential thrombin inhibitors Tetrahedron. 59: 7047-7056. DOI: 10.1016/S0040-4020(03)00919-0  0.424
2003 Hanessian S, Kornienko A, Swayze EE. Probing the functional requirements of the L-haba side-chain of amikacin - Synthesis, 16S A-site rRNA binding, and antibacterial activity Tetrahedron. 59: 995-1007. DOI: 10.1016/S0040-4020(02)01625-3  0.358
2003 Hanessian S, Tremblay M, Swayze EE. Tobramycin analogues with C-5 aminoalkyl ether chains intended to mimic rings III and IV of paromomycin Tetrahedron. 59: 983-993. DOI: 10.1016/S0040-4020(02)01624-1  0.607
2003 Hanessian S, Machaalani R. A highly stereocontrolled and efficient synthesis of α- and β-pseudouridines Tetrahedron Letters. 44: 8321-8323. DOI: 10.1016/J.Tetlet.2003.09.103  0.347
2003 Saladino R, Ciambecchini U, Hanessian S. Synthesis of 1′-Homo-N-nucleosides from Hexitols European Journal of Organic Chemistry. 4401-4405. DOI: 10.1002/Ejoc.200300328  0.387
2002 Hanessian S, Wang J, Montgomery D, Stoll V, Stewart KD, Kati W, Maring C, Kempf D, Hutchins C, Laver WG. Design, synthesis, and neuraminidase inhibitory activity of GS-4071 analogues that utilize a novel hydrophobic paradigm. Bioorganic & Medicinal Chemistry Letters. 12: 3425-9. PMID 12419376 DOI: 10.1016/S0960-894X(02)00732-1  0.381
2002 Hanessian S, Margarita R, Hall A, Johnstone S, Tremblay M, Parlanti L. Total synthesis and structural confirmation of the marine natural product Dysinosin A: a novel inhibitor of thrombin and Factor VIIa. Journal of the American Chemical Society. 124: 13342-3. PMID 12418860 DOI: 10.1021/Ja0208153  0.64
2002 Hanessian S, Therrien E, Granberg K, Nilsson I. Targeting thrombin and factor VIIa: design, synthesis, and inhibitory activity of functionally relevant indolizidinones. Bioorganic & Medicinal Chemistry Letters. 12: 2907-11. PMID 12270173 DOI: 10.1016/S0960-894X(02)00612-1  0.331
2002 Hanessian S, Claridge S, Johnstone S. The power of visual imagery in synthesis planning. Stereocontrolled approaches to CGP-60536B, a potent renin inhibitor. The Journal of Organic Chemistry. 67: 4261-74. PMID 12054962 DOI: 10.1021/Jo011184I  0.4
2002 Hanessian S, Buckle R, Bayrakdarian M. Design and synthesis of a novel class of constrained tricyclic pyrrolizidinone carboxylic acids as carbapenem mimics. The Journal of Organic Chemistry. 67: 3387-97. PMID 12003550 DOI: 10.1021/Jo0111715  0.793
2002 Hanessian S, Mascitti V, Rogel O. Synthesis of a potent antagonist of E-selectin. The Journal of Organic Chemistry. 67: 3346-54. PMID 12003545 DOI: 10.1021/Jo0110956  0.366
2002 Hanessian S, Bayrakdarian M, Luo X. Total synthesis of A-315675: a potent inhibitor of influenza neuraminidase. Journal of the American Chemical Society. 124: 4716-21. PMID 11971721 DOI: 10.1021/Ja0126226  0.797
2002 Hanessian S, Angiolini M. Conformationally stable and constrained macrocarbocyclic pseudopeptide mimics of beta-hairpin structures. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 111-7. PMID 11822444 DOI: 10.1002/1521-3765(20020104)8:1<111::Aid-Chem111>3.0.Co;2-S  0.372
2002 Hanessian S, Jnoff E, Griffin AM. Penicillamine as a ligand in the catalytic asymmetric reduction of ketones Canadian Journal of Chemistry. 80: 885-888. DOI: 10.1139/V01-174  0.328
2002 Hanessian S, Mascitti V, Lu PP, Ishida H. One-step stereocontrolled synthesis of α-anomeric carboxylic acid esters from unprotected glycosyl donors: A water-soluble aspirin pro-drug analogue Synthesis. 1959-1968. DOI: 10.1055/S-2002-34372  0.338
2002 Hanessian S, Ma J, Wang W, Gai Y. Total Synthesis of Bafilomycin A1Relying on Iterative 1,2-Induction in Acyclic Precursors [J. Am.Chem. Soc.2001,123, 10200−10206]. Journal of the American Chemical Society. 124: 7249-7249. DOI: 10.1021/Ja025105B  0.52
2002 Hanessian S, Bayrakdarian M. Solution- and solid-phase asymmetric synthesis of substituted N-hydroxypyrrolidine dicarboxylic acids Tetrahedron Letters. 43: 9441-9444. DOI: 10.1016/S0040-4039(02)02288-8  0.787
2002 Hanessian S, Van Otterlo WAL, Nilsson I, Bauer U. Stereocontrolled synthesis of a prototype library of enantiopure 2,4-disubstituted 4-aryl-6-piperidinones and piperidines Tetrahedron Letters. 43: 1995-1998. DOI: 10.1016/S0040-4039(02)00184-3  0.35
2002 Hanessian S, Seid M, Nilsson I. Stereocontrolled synthesis of enantiopure diversely functionalized prototypical piperidinone libraries, and constrained analogs of 4-substituted 2-amino adipic acid Tetrahedron Letters. 43: 1991-1994. DOI: 10.1016/S0040-4039(02)00183-1  0.397
2002 Hanessian S, Bayrakdarian M. Asymmetric synthesis of diversely substituted N-hydroxypyrrolidines using cycloadditions with chiral nitrone enolate/ylids Tetrahedron Letters. 43: 967-971. DOI: 10.1016/S0040-4039(01)02305-X  0.794
2002 Hanessian S, Compain P. Corrigendum to “Lewis acid promoted cyclocondensations of α-ketophosphonoenoates with dienes—from Diels–Alder to hetero Diels–Alder reactions” Tetrahedron. 58: 10087. DOI: 10.1016/S0040-4020(02)01353-4  0.59
2002 Hanessian S, Compain P. Lewis acid promoted cyclocondensations of alpha;-ketophosphonoenoates with dienes - From Diels-Alder to hetero Diels-Alder reactions Tetrahedron. 58: 6521-6529. DOI: 10.1016/S0040-4020(02)00662-2  0.614
2002 Hanessian S, Mauduit M, Demont E, Talbot C. Synthesis of desymmetrized, enantiopure dihydro-methano-diarylazocines: Topologically interesting eyeteaser molecules Tetrahedron. 58: 1485-1490. DOI: 10.1016/S0040-4020(02)00012-1  0.371
2001 Hanessian S, Ma J, Wang W, Gai Y. Total synthesis of bafilomycin A(1) relying on iterative 1,2-induction in acyclic precursors. Journal of the American Chemical Society. 123: 10200-6. PMID 11603969 DOI: 10.1021/Ja011452U  0.556
2001 Hanessian S, Fu JM. Total synthesis of polyoximic acid Canadian Journal of Chemistry. 79: 1812-1826. DOI: 10.1139/V01-171  0.387
2001 Hanessian S, Ma J. From glyceraldehyde to functionalized enantiopure tetrahydronaphthalenes and indanes Tetrahedron Letters. 42: 8785-8788. DOI: 10.1016/S0040-4039(01)01914-1  0.513
2001 Hanessian S, Moitessier N, Cantin LD. Design and synthesis of MMP inhibitors using N-arylsulfonylaziridine hydroxamic acids as constrained scaffolds Tetrahedron. 57: 6885-6900. DOI: 10.1016/S0040-4020(01)00641-X  0.688
2001 Hanessian S, Huynh HK, Reddy GV, Duthaler RO, Katopodis A, Streiff MB, Kinzy W, Oehrlein R. Synthesis of Gal determinant epitopes, their glycomimetic variants, and trimeric clusters - Relevance to tumor associated antigens and to discordant xenografts Tetrahedron. 57: 3281-3290. DOI: 10.1016/S0040-4020(01)00195-8  0.676
2001 Hanessian S, Tremblay M, Kornienko A, Moitessier N. Design, modeling and synthesis of functionalized paromamine analogs Tetrahedron. 57: 3255-3265. DOI: 10.1016/S0040-4020(01)00194-6  0.61
2000 Hanessian S, Gomtsyan A, Malek N. Asymmetric conjugate additions of chiral phosphonamide anions to alpha,beta-unsaturated carbonyl compounds. A versatile method for vicinally substituted chirons The Journal of Organic Chemistry. 65: 5623-31. PMID 10970301 DOI: 10.1021/Jo000388G  0.388
2000 Hanessian S, Griffin AM, Cantin LD. Asymmetric synthesis of functionalized carbocycles and heterocycles. Chirality. 12: 342-5. PMID 10824149 DOI: 10.1002/(Sici)1520-636X(2000)12:5/6<342::Aid-Chir7>3.0.Co;2-Y  0.699
2000 Hanessian S, Rogel O. Synthesis of glycophostones: cyclic phosphonate analogues of biologically relevant sugars The Journal of Organic Chemistry. 65: 2667-74. PMID 10808439 DOI: 10.1021/Jo991696L  0.344
2000 Hanessian S, Sgarbi PW. Design and synthesis of mimics of S-adenosyl-L-homocysteine as potential inhibitors of erythromycin methyltransferases. Bioorganic & Medicinal Chemistry Letters. 10: 433-7. PMID 10743942 DOI: 10.1016/S0960-894X(00)00021-4  0.364
2000 Hanessian S, Bayrakdarian M. Pyrrolidine as a cogwheel-like scaffold for the deployment of diverse functionality through cycloaddition reactions of metallo-1,3-dipoles in aqueous media. Bioorganic & Medicinal Chemistry Letters. 10: 427-31. PMID 10743941 DOI: 10.1016/S0960-894X(00)00020-2  0.752
2000 Hanessian S, Balaux E, Musil D, Olsson LL, Nilsson I. Exploring the chiral space within the active site of alpha-thrombin with a constrained mimic of D-Phe-Pro-Arg--design, synthesis, inhibitory activity, and X-ray structure of an enzyme-inhibitor complex. Bioorganic & Medicinal Chemistry Letters. 10: 243-7. PMID 10698445 DOI: 10.1016/S0960-894X(99)00669-1  0.349
2000 Hanessian S, Sharma R. The synthesis of bicyclic piperazine-2-carboxylic acids from L-proline Heterocycles. 52: 1231-1239. DOI: 10.3987/Com-99-S136  0.351
2000 Hanessian S, Cantin LD. The synthesis of enantiomerically pure disubstituted aziridines and N- alkoxy aziridines Tetrahedron Letters. 41: 787-790. DOI: 10.1016/S0040-4039(99)02211-X  0.683
2000 Hanessian S, Demont E, Van Otterlo WAL. From serine to functionalized enantiopure tetrahydroisoquinolines Tetrahedron Letters. 41: 4999-5003. DOI: 10.1016/S0040-4039(00)00765-6  0.381
2000 Hanessian S, Moitessier N, Wilmouth S. Tetrahydrofuran as a scaffold for peptidomimetics. Application to the design and synthesis of conformationally constrained metalloproteinase inhibitors Tetrahedron. 56: 7643-7660. DOI: 10.1016/S0040-4020(00)00687-6  0.339
1999 Hanessian S, McNaughton-Smith G. Synthesis of a versatile peptidomimetic scaffold. Methods in Molecular Medicine. 23: 161-174. PMID 21380897 DOI: 10.1385/0-89603-517-4:161  0.347
1999 Hanessian S, Cantin LD, Andreotti D. Total Synthesis and Absolute Configuration of (-)-Anthoplalone. The Journal of Organic Chemistry. 64: 4893-4900. PMID 11674567 DOI: 10.1021/Jo990302N  0.705
1999 Hanessian S, Rogel O. Synthesis of a phostone glycomimetic of the endothelin converting enzyme inhibitor phosphoramidon Bioorganic and Medicinal Chemistry Letters. 9: 2441-2446. PMID 10476884 DOI: 10.1016/S0960-894X(99)00401-1  0.324
1999 Hanessian S, Bernstein N, Yang RY, Maguire R. Asymmetric synthesis of L-azetidine-2-carboxylic acid and 3-substituted congeners--conformationally constrained analogs of phenylalanine, naphthylalanine, and leucine. Bioorganic & Medicinal Chemistry Letters. 9: 1437-42. PMID 10360752 DOI: 10.1016/S0960-894X(99)00218-8  0.354
1999 Hanessian S, Reinhold U, Saulnier M, Claridge S. Probing the importance of spacial and conformational domains in captopril analogs for angiotensin converting enzyme activity. Bioorganic & Medicinal Chemistry Letters. 8: 2123-8. PMID 9873498 DOI: 10.1016/S0960-894X(98)00377-1  0.325
1999 Hanessian S, Johnstone S. Synthesis of Hydroxamic Esters via Alkoxyaminocarbonylation of β-Dicarbonyl Compounds Journal of Organic Chemistry. 64: 5896-5903. DOI: 10.1021/Jo990353K  0.332
1999 Hanessian S, Luo X, Schaum R. Synthesis and folding preferences of γ-amino acid oligopeptides: stereochemical control in the formation of a reverse turn and a helix Tetrahedron Letters. 40: 4925-4929. DOI: 10.1016/S0040-4039(99)00860-6  0.354
1999 Hanessian S, Ma J, Wang W. One- and two-directional iterative 1,2-asymmetric induction in acyclic systems—easy access to anti,anti and anti,syn dipropionate and diphenylacetate stereotriads Tetrahedron Letters. 40: 4627-4630. DOI: 10.1016/S0040-4039(99)00783-2  0.503
1999 Hanessian S, Ma J, Wang W. Stereocontrolled solution and solid phase enolate alkylations and hydroxylations — generation of three and four contiguous stereogenic carbon atoms in acyclic systems Tetrahedron Letters. 40: 4631-4634. DOI: 10.1016/S0040-4039(99)00782-0  0.49
1999 Hanessian S, Huynh HK. Solution and solid phase p-alkoxybenzylation of alcohols under neutral conditions Tetrahedron Letters. 40: 671-674. DOI: 10.1016/S0040-4039(98)02531-3  0.655
1999 Hanessian S, Reddy B. Total synthesis of tricyclic ?-lactams Tetrahedron. 55: 3427-3443. DOI: 10.1016/S0040-4020(98)01152-1  0.439
1998 Hanessian S, Huynh HK, Reddy GV, McNaughton-Smith G, Ernst B, Kolb HC, Magnani J, Sweeley C. Exploration of beta-turn scaffolding motifs as components of sialyl Le(X) mimetics and their relevance to P-selectin. Bioorganic & Medicinal Chemistry Letters. 8: 2803-8. PMID 9873626 DOI: 10.1016/S0960-894X(98)00500-9  0.666
1998 Hanessian S, Grillo TA. Stereocontrolled Total Synthesis of an Annonacin A-Type Acetogenin: Pseudoannonacin A?† Journal of Organic Chemistry. 63: 1049-1057. DOI: 10.1021/Jo9713621  0.395
1998 Hanessian S, Lu P, Ishida H. One-Step, Stereocontrolled Synthesis of Glycosyl 1-Phosphates, Uridine-5‘-diphosphogalactose, and Uridine-5‘-diphosphoglucose from Unprotected Glycosyl Donors Journal of the American Chemical Society. 120: 13296-13300. DOI: 10.1021/Ja982783I  0.342
1998 Hanessian S, Margarita R. 1,3-Asymmetric induction in dianionic allylation reactions of amino acid derivatives-synthesis of functionally useful enantiopure glutamates, pipecolates and pyroglutamates Tetrahedron Letters. 39: 5887-5890. DOI: 10.1016/S0040-4039(98)00900-9  0.385
1998 Hanessian S, Margarita R, Hall A, Luo X. 1,2-Asymmetric induction in dianionic allylation reactions of amino acid derivatives-synthesis of functionally useful, enantiopure aspartates and constrained scaffolds Tetrahedron Letters. 39: 5883-5886. DOI: 10.1016/S0040-4039(98)00899-5  0.402
1998 Hanessian S, Xie F. Exploring functional and molecular diversity with polymer-bound p-alkoxybenzyl ethers - Scope and applicaitons of preparatively useful organic reactions Tetrahedron Letters. 39: 737-740. DOI: 10.1016/S0040-4039(97)10685-2  0.309
1998 Hanessian S, Cantin L. Synthesis and Biological Evaluation of Constrained Phosphonoglutamic Acids as Metabotropic Agents Molecules Online. 2: 46-52. DOI: 10.1007/S007830050054  0.699
1997 Bennani YL, Hanessian S. trans-1,2-Diaminocyclohexane Derivatives as Chiral Reagents, Scaffolds, and Ligands for Catalysis: Applications in Asymmetric Synthesis and Molecular Recognition. Chemical Reviews. 97: 3161-3196. PMID 11851488 DOI: 10.1021/Cr9407577  0.364
1997 Hanessian S, Pan J, Carnell A, Bouchard H, Lesage L. Total Synthesis of (-)-Reserpine Using the Chiron Approach. The Journal of Organic Chemistry. 62: 465-473. PMID 11671435 DOI: 10.1021/Jo961713W  0.434
1997 Hanessian S, Yang R, Sancéau J. Synthesis of 1-N-hydroxyhydantoin 5-phosphates as potential fungicides Canadian Journal of Chemistry. 75: 712-715. DOI: 10.1139/V97-085  0.384
1997 Hanessian S, Park H, Yang R. Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of Anti- and Syn-β-Amino Alcohols with Functionalized Allyl Groups Synlett. 1997: 353-354. DOI: 10.1055/S-1997-804  0.35
1997 Hanessian S, Park H, Yang R. Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of Phe-Phe Hydroxyethylene Dipeptide Isosteres Synlett. 1997: 351-352. DOI: 10.1055/S-1997-803  0.358
1997 Hanessian S, Wang W, Gai Y, Olivier E. A General and Stereocontrolled Strategy for the Iterative Assembly of Enantiopure Polypropionate Subunits:  Synthesis of the C19−C28 Segment of Rifamycin S from a Single Chiron Journal of the American Chemical Society. 119: 10034-10041. DOI: 10.1021/Ja970251G  0.348
1997 Hanessian S, Griffin A, Devasthale PV. Synthesis of conformationally constrained potential inhibitors of mammalian metalloproteinases Bioorganic & Medicinal Chemistry Letters. 7: 3119-3124. DOI: 10.1016/S0960-894X(97)10171-8  0.394
1997 Hanessian S, Reddy GV, Huynh HK, Jingwen P, Pedatella S, Ernst B, Kolb HC. Design and synthesis of sialyl Le(x) mimetics based on carbocyclic scaffolds derived from (-)-quinic acid Bioorganic and Medicinal Chemistry Letters. 7: 2729-2734. DOI: 10.1016/S0960-894X(97)10077-4  0.708
1997 Hanessian S, Griffin AM, Rozema MJ. Tricyclic β-lactams: Total synthesis and antibacterial activity of 5α-methoxyethyl and 5α-hydroxyethyl trinems Bioorganic and Medicinal Chemistry Letters. 7: 1857-1862. DOI: 10.1016/S0960-894X(97)00326-0  0.722
1997 Hanessian S, Yang H. Design of a novel secondary structure scaffolding device: Induction of a reverse turn in tetrapeptides by incorporating a β-amino acid and stereocontrolled free radical α-substitution reactions in peptide motifs Tetrahedron Letters. 38: 3155-3158. DOI: 10.1016/S0040-4039(97)00612-6  0.332
1997 Hanessian S, Cantin L, Roy S, Andreotti D, Gomtsyan A. The synthesis of enantiomerically pure, symmetrically substituted cyclopropane phosphonic acids — A constrained analog of the GABA antagonist phaclophen Tetrahedron Letters. 38: 1103-1106. DOI: 10.1016/S0040-4039(96)02518-X  0.697
1997 Hanessian S, Schaum R. 1,3-Asymmetric induction in enolate alkylation reactions of N-protected γ-amino acid derivatives Tetrahedron Letters. 38: 163-166. DOI: 10.1016/S0040-4039(96)02263-0  0.352
1997 Hanessian S, McNaughton-Smith G, Lombart H, Lubell WD. Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics Tetrahedron. 53: 12789-12854. DOI: 10.1016/S0040-4020(97)00476-6  0.309
1997 Hanessian S, Abad-Grillo T, McNaughton-Smith G. Synthesis of (4S)-hydroxymethyl-(2R)-(2-propyl)-butyrolactone: A quest for a practical route to an important hydroxyethylene isostere chiron Tetrahedron. 53: 6281-6294. DOI: 10.1016/S0040-4020(97)00298-6  0.307
1997 Hanessian S, Reinhold U, Gentile G. The Synthesis of Enantiopure ω‐Methanoprolines and ω‐Methanopipecolic Acids by a Novel Cyclopropanation Reaction: The “Flattering” of Proline Angewandte Chemie. 36: 1881-1884. DOI: 10.1002/Anie.199718811  0.377
1996 Hanessian S, Ninkovic S. Total synthesis of isodeoxypodophyllotoxin using the Me3Sn radical initiated carbocyclization Canadian Journal of Chemistry. 74: 1880-1888. DOI: 10.1139/V96-211  0.33
1996 Hanessian S, Qiu D, Prabhanjan H, Reddy GV, Lou B. Synthesis of clustered D-GalNAc (Tn) and D-Galβ(1→3)GalNAc (T) antigenic motifs using a pentaerythritol scaffold Canadian Journal of Chemistry. 74: 1738-1747. DOI: 10.1139/V96-192  0.306
1996 Hanessian S, Prabhanjan H, Qiu D, Nambiar S. Synthesis of chemically and functionally diverse scaffolds from pentaerythritol Canadian Journal of Chemistry. 74: 1731-1737. DOI: 10.1139/V96-191  0.394
1996 Hanessian S, Sancéau J. Asymmetric synthesis of taxol arid taxotère side chains by enolate hydroxylation Canadian Journal of Chemistry. 74: 621-624. DOI: 10.1139/V96-066  0.376
1996 Hanessian S, Ninkovic S. Stereoselective Synthesis of (−)-α-Kainic Acid and (+)-α-Allokainic Acid via Trimethylstannyl-Mediated Radical Carbocyclization and Oxidative Destannylation Journal of Organic Chemistry. 61: 5418-5424. DOI: 10.1021/Jo9604088  0.329
1996 Hanessian S, Andreotti aD, Gomtsyan A. Asymmetric Synthesis of Enantiomerically Pure and Diversely Functionalized Cyclopropanes J. Am. Chem. Soc. 1995, 117, 10393−10394 Journal of the American Chemical Society. 118: 2537-2537. DOI: 10.1021/Ja955040V  0.362
1996 Hanessian S, McNaughton-Smith G. A versatile synthesis of a β-turn peptidomimetic scaffold: An approach towards a designed model antagonist of the tachykinin NK-2 receptor Bioorganic & Medicinal Chemistry Letters. 6: 1567-1572. DOI: 10.1016/S0960-894X(96)00275-2  0.376
1996 Hanessian S, Tehim A, Meng Q, Granberg K. A remarkably facile and stereochemically controlled fragmentation reaction in the hygrolide group of macrolide antibiotics Tetrahedron Letters. 37: 9001-9004. DOI: 10.1016/S0040-4039(96)02113-2  0.362
1996 Hanessian S, Yang R. Enantioselective allylation of α-ketoester oximes with an external chiral ligand: Asymmetric synthesis of allylglycines and allylalanine Tetrahedron Letters. 37: 8997-9000. DOI: 10.1016/S0040-4039(96)02112-0  0.384
1996 Hanessian S, Ninkovic S, Reinhold U. The synthesis of 4,5-methano congeners of α-kainic and α-allo-kainic acids as probes for glutamate receptors Tetrahedron Letters. 37: 8971-8974. DOI: 10.1016/S0040-4039(96)02105-3  0.373
1996 Hanessian S, Reinhold U, Ninkovic S. The stereocontrolled synthesis of enantiopure α-methano heterocycles and constrained amino acid analogs Tetrahedron Letters. 37: 8967-8970. DOI: 10.1016/S0040-4039(96)02104-1  0.363
1996 Hanessian S, Devasthale PV. Design and synthesis of novel, pseudo C2 symmetric inhibitors of HIV protease Bioorganic & Medicinal Chemistry Letters. 6: 2201-2206. DOI: 10.1016/0960-894X(96)00392-7  0.336
1996 Hanessian S, Wang W, Gai Y. Stereocontrolled sequential functionalization in acyclic systems by exploiting internal 1,2-asymmetric induction — generation of symmetry-related polyamino alcohol motifs Tetrahedron Letters. 37: 7477-7480. DOI: 10.1016/0040-4039(96)01754-6  0.346
1996 Hanessian S, Gai Y, Wang W. Stereocontrolled Functionalization In Acyclic Systems By Exploiting Internal 1,2-Asymmetric Induction-Generation Of Polypropionate And Related Motifs Tetrahedron Letters. 37: 7473-7476. DOI: 10.1016/0040-4039(96)01753-4  0.335
1996 Hanessian S, Yang R. Solution and solid phase synthesis of 5-alkoxyhydantoin libraries with a three-fold functional diversity Tetrahedron Letters. 37: 5835-5838. DOI: 10.1016/0040-4039(96)01244-0  0.332
1996 Hanessian S, Yang R. The asymmetric synthesis of allylglycine and other unnatural α-amino acids via zinc-mediated allylation of oximes in aqueous media Tetrahedron Letters. 37: 5273-5276. DOI: 10.1016/0040-4039(96)01118-5  0.391
1996 Hanessian S, Devasthale PV. Generation of functional diversity via nitroaldol condensations of α-aminoacid aldehydes — A new and stereocontrolled route to acyclic 1,3-diamino-2-alcohols Tetrahedron Letters. 37: 987-990. DOI: 10.1016/0040-4039(95)02359-3  0.36
1996 Bennani YL, Hanessian S. The asymmetric synthesis of α-substituted α-methyl and α-phenyl phosphonic acids: Design, carbanion geometry, reactivity and preparative aspects of chiral alkyl bicyclic phosphonamides Tetrahedron. 52: 13837-13866. DOI: 10.1016/0040-4020(96)00829-0  0.345
1996 Vatèle J, Hanessian S. Design and reactivity of organic functional groups - preparation and nucleophilic displacement reactions of imidazole-1-sulfonates (imidazylates) Tetrahedron. 52: 10557-10568. DOI: 10.1016/0040-4020(96)00586-8  0.355
1995 Hanessian S, Yang R. Synthesis of N-Hydroxy α-Amino Acids from α-Hydroxy Acids with High Enantiomeric Purity Synlett. 1995: 633-634. DOI: 10.1055/S-1995-5031  0.331
1995 Hanessian S, Benalil A, Laferriere C. The Synthesis of Functionalized Cyclodextrins As Scaffolds and Templates for Molecular Diversity, Catalysis, and Inclusion Phenomena The Journal of Organic Chemistry. 60: 4786-4797. DOI: 10.1021/Jo00120A023  0.358
1995 Hanessian S, Andreotti D, Gomtsyan A. Asymmetric synthesis of enantiomerically pure and diversely functionalized cyclopropanes. Journal of the American Chemical Society. 117: 10393-10394. DOI: 10.1021/Ja00146A029  0.396
1995 Hanessian S, Rozema MJ, Reddy GB, Braganza JF. Tricyclic β-lactams: total synthesis and antibacterial activity of 5α- and 5β-methoxy-tribactams Bioorganic and Medicinal Chemistry Letters. 5: 2535-2540. DOI: 10.1016/0960-894X(95)00445-Y  0.72
1995 Hanessian S, Condé JJ, Lou B. The stereocontrolled synthesis of 1,2-cis furanosyl nucleosides via a novel anomeric activation Tetrahedron Letters. 36: 5865-5868. DOI: 10.1016/0040-4020(96)00611-4  0.344
1995 Hanessian S, Benalil A, Simard M, Bélanger-Gariépy F. Crystal structures and molecular conformations of mono-6-azido-6-deoxy α-Cyclodextrin and mono-2-O-allyl-α-cyclodextrin -The formation of polymeric helical inclusion complexes Tetrahedron. 51: 10149-10158. DOI: 10.1016/0040-4020(95)00609-C  0.313
1995 Hanessian S, Benalil A, Viet MTP. The intramolecular inclusion of aromatic esters within β-cyclodextrin as a function of chain length — a detailed NMR study Tetrahedron. 51: 10131-10148. DOI: 10.1016/0040-4020(95)00608-B  0.323
1995 Hanessian S, Sancéau J, Chemla P. Synthesis of surrogate structures related to the herbicidal agent hydantocidin Tetrahedron. 51: 6669-6678. DOI: 10.1016/0040-4020(95)00324-2  0.407
1994 Hanessian S, Bennani YL. Electrophilic Amination and Azidation of Chiral α-Alkyl Phosphonamides: Asymmetric Syntheses of α-Amino α-Alkyl Phosphonic Acids† Synthesis. 1994: 1272-1274. DOI: 10.1055/S-1994-25679  0.319
1994 Hanessian S, Girard C. One Step α-Deoxygenation of Unprotected Aldonolactones using Samarium Diiodide-THF/H2O System - A New Synthesis of 2-Deoxy-D-Ribose Synlett. 1994: 861-862. DOI: 10.1055/S-1994-23034  0.349
1994 Hanessian S, Gomtsyan A, Payne A, Herve Y. Asymmetric conjugate additions of chiral allyl- and crotylphosphonamide anions to .alpha.,.beta.-unsaturated carbonyl compounds: highly stereocontrolled access to vicinally substituted carbon centers and chemically asymmetrized chirons. [Erratum to document cited in CA119:250032] Journal of Organic Chemistry. 59: 3242-3242. DOI: 10.1021/Jo00090A055  0.322
1994 Hanessian S, Galéotti N, Rosen P, Oliva G, Babu S. Synthesis of carbohydrate phostones as potential glycomimetics Bioorganic & Medicinal Chemistry Letters. 4: 2763-2768. DOI: 10.1016/S0960-894X(01)80591-6  0.358
1994 Hanessian S, Raghavan S. Design and synthesis of a prototypical non-peptidic inhibitor model for the enzme renin Bioorganic and Medicinal Chemistry Letters. 4: 1697-1702. DOI: 10.1016/S0960-894X(00)80364-9  0.32
1994 Hanessian S, Gomtsyan A. Highly stereocontrolled sequential asymmetric Michael addition reactions with cinnamate esters - generation of three and four contiguous stereogenic centers on seven-carbon acyclic motifs Tetrahedron Letters. 35: 7509-7512. DOI: 10.1016/S0040-4039(00)78330-4  0.362
1994 Hanessian S, Meng Q, Olivier E. An unprecedented ring expansion in the Macrolide series - synthesis of iso-bafilomycin A1 Tetrahedron Letters. 35: 5393-5396. DOI: 10.1016/S0040-4039(00)73508-8  0.375
1994 Hanessian S, Reddy G. Synthesis of tricyclic β-lactams - functionally and topologically novel carbacephems Bioorganic & Medicinal Chemistry Letters. 4: 2285-2290. DOI: 10.1016/0960-894X(94)85026-7  0.389
1994 Hanessian S, Rozema MJ. Synthesis and biological evaluation of 1-substituted-7-(1-hydroxyethyl) carbacephems - a class of "hybrid" bicyclic β-lactams Bioorganic and Medicinal Chemistry Letters. 4: 2279-2284. DOI: 10.1016/0960-894X(94)85025-9  0.748
1993 Hanessian S, Bennani YL, Leblanc Y. Efficient olefination with α-alkyl cyclic phosphonamides Heterocycles. 35: 1411-1424. DOI: 10.3987/Com-93-S(T)145  0.358
1993 Hanessian S. Reflections on the total synthesis of natural products: Art, craft, logic, and the chiron approach Pure and Applied Chemistry. 65: 1189-1204. DOI: 10.1351/Pac199365061189  0.362
1993 Hanessian S, Vanasse B, Yang H, Alpegiani M. Highly stereocontrolled syntheses of 2,3-disubstituted 1,4-butyrolactones using ionic and free radical reactions Canadian Journal of Chemistry. 71: 1407-1411. DOI: 10.1139/V93-182  0.304
1993 Hanessian S, Wang J. Synthesis and biological evaluation of novel chiral non-racemic diaminoplatinum analogs based on a tetrahydropyran motif Canadian Journal of Chemistry. 71: 886-895. DOI: 10.1139/V93-118  0.388
1993 Hanessian S, Gauthier J, Okamoto K, Beauchamp A, Theophanides T. Synthesis of diaminodideoxyalditol analogs of cisplatin as antitumor agents Canadian Journal of Chemistry. 71: 880-885. DOI: 10.1139/V93-117  0.323
1993 Hanessian S, Bennani YL, Hervé Y. A Novel Asymmetric Synthesis of α- and β-Amino Aryl Phosphonic Acids Synlett. 1993: 35-36. DOI: 10.1055/S-1993-22337  0.35
1993 Hanessian S, Tehim A, Chen P. Total synthesis of (-)-tetrahydrolipstatin Journal of Organic Chemistry. 58: 7768-7781. DOI: 10.1021/Jo00079A022  0.414
1993 Hanessian S, Gomtsyan A, Payne A, Herve Y, Beaudoin S. Asymmetric conjugate additions of chiral allyl- and crotylphosphonamide anions to .alpha.,.beta.-unsaturated carbonyl compounds: highly stereocontrolled access to vicinally substituted carbon centers and chemically asymmetrized chirons Journal of Organic Chemistry. 58: 5032-5034. DOI: 10.1021/Jo00071A004  0.399
1993 Hanessian S, Couture CA, Georgopapadakou N. Probing the binding site of the penicillin side-chain based on the tipper-strominger hypothesis Bioorganic & Medicinal Chemistry Letters. 3: 2323-2328. DOI: 10.1016/S0960-894X(01)80948-3  0.309
1993 Hanessian S, Fu J, Chiara JL, Fabio RD. Total synthesis of (+)-polyoximic acid - cis-3-ethylidene-L-azetidine-2-carboxylic acid Tetrahedron Letters. 34: 4157-4160. DOI: 10.1016/S0040-4039(00)60516-6  0.365
1993 Hanessian S, Fu J, Tu Y, Isono K. Structural identity and stereochemical revision of polyoximic acid Tetrahedron Letters. 34: 4153-4156. DOI: 10.1016/S0040-4039(00)60515-4  0.32
1993 Hanessian S, Chemla P, Tu Y. Bis-homo avermectin B1a - A semi-synthetic analog with a trienic 18-membered macrocyclic ring Tetrahedron Letters. 34: 1407-1410. DOI: 10.1016/S0040-4039(00)60303-9  0.354
1993 Hanessian S, Beaudoin S. Versatile synthesis of alicyclic and acyclic compounds with alternate and remote C-methyl substitution patterns via asymmetric sequential olefination and ene reactions Tetrahedron Letters. 33: 7659-7662. DOI: 10.1016/0040-4039(93)88009-8  0.391
1993 Hanessian S, Beaudoin S. Studies in asymmetric olefinations - the synthesis of enantiomerically pure allylidene, alkylidene, and benzylidene cyclohexanes Tetrahedron Letters. 33: 7655-7658. DOI: 10.1016/0040-4039(93)88008-7  0.325
1992 Simard M, Beaudoin S, Hanessian S. Structure of a chiral bicyclic β‐hydroxyphosphonamide ‐ a product of kinetic resolution in an olefination reaction, C22H35N2O2P Acta Crystallographica Section C. 48: 1535-1537. DOI: 10.1107/S0108270191014695  0.319
1992 Belanger-Gariepy F, Leger R, Hanessian S. Structure of a bicyclic organostannane resulting from a trimethyltin hydride addition-cyclization reaction Acta Crystallographica Section C-Crystal Structure Communications. 48: 1309-1310. DOI: 10.1107/S0108270191013793  0.319
1992 Hanessian S, Léger R. Total Synthesis of the Lignan Antibiotic Burseran and a Novel Approach to the Podophyllotoxin Skeleton Synlett. 1992: 402-404. DOI: 10.1055/S-1992-21359  0.36
1992 Hanessian S, Sumi K, Vanasse B. The Stereocontrolled Synthesis of (2S,3R)-3-Alkyl-L-aspartic Acids Using a 2-Azetidinone Framework as a Chiral Template Synlett. 1992: 33-34. DOI: 10.1055/S-1992-21255  0.347
1992 Hanessian S, Girard C, Chiara JL. A practical synthesis of 2-deoxy aldonolactones via a SmI2-mediated α-deoxygenation reaction Tetrahedron Letters. 33: 573-576. DOI: 10.1016/S0040-4039(00)92313-X  0.33
1992 Sumi K, Fabio RD, Hanessian S. The stereocontrolled synthesis of versatile carbapenem intermediates using the Barton O-acyl 2-thiophyridylhydroxamate fragmentation Tetrahedron Letters. 33: 749-752. DOI: 10.1016/S0040-4039(00)77706-9  0.365
1992 Boulanger Y, Tu Y, Ratovelomanana V, Purisima E, Hanessian S. Conformation of MurNAc-L-Ala-D-iGln (MDP) and of a constrained analog using 1H NMR data and molecular modeling Tetrahedron. 48: 8855-8868. DOI: 10.1016/S0040-4020(01)81985-2  0.312
1992 Hanessian S, Léger R, Alpegiani M. Free radical-induced C-allylation of α-bromolactones. Synthesis of 2-C-allyl-2-deoxy-d-arabino-and -d-ribono-1,4-lactones Carbohydrate Research. 228: 145-155. DOI: 10.1016/S0008-6215(00)90556-1  0.328
1991 Hanessian S, Sumi K. On the stereochemical divergence in the conjugate addition of lithium dimethylcuprate/trimethylsilyl chloride to γ-alkoxy and γ-ureido α,β-unsaturated esters Synthesis. 1991: 1083-1089. DOI: 10.1055/S-1991-28396  0.311
1991 Hanessian S, Ratovelomanana V. Synthesis of a Conformationally Constrained Analog ofN-Acetylmuramyl Dipeptide (MDP) Synlett. 1991: 222-224. DOI: 10.1055/S-1991-20684  0.431
1991 Hanessian S, Faucher AM. General stereocontrolled strategy for the heteroyohimbine alkaloids: the total synthesis of (-)-ajmalicine and (+)-19-epiajmalicine The Journal of Organic Chemistry. 56: 2947-2949. DOI: 10.1021/Jo00009A001  0.35
1991 Chiara JL, Cabri W, Hanessian S. The stereocontrolled formation of cyclic vicinal cis-diols via a samarium diiodide pinacol coupling of dialdehydes Tetrahedron Letters. 32: 1125-1128. DOI: 10.1016/S0040-4039(00)92024-0  0.599
1991 Hanessian S, Chemla P. Synthesis of 19-epi-avermectin A1a from avermectin B1a Tetrahedron Letters. 32: 2719-2722. DOI: 10.1016/0040-4039(91)85067-F  0.318
1990 Hanessian S, Franco J, Larouche B. The psychobiological basis of heuristic synthesis planning - man, machine and the chiron approach Pure and Applied Chemistry. 62: 1887-1910. DOI: 10.1351/Pac199062101887  0.364
1990 Hanessian S, Bennani YL, Fabio RD. Intramolecular free-radical ring closures. III, Structure of a chiral δ-lactone Acta Crystallographica Section C-Crystal Structure Communications. 46: 939-941. DOI: 10.1107/S0108270189010796  0.339
1990 Hanessian S, Bennani YL, Fabio RD. Intramolecular free-radical ring closures. I, structure of a chiral bicyclic lactone Acta Crystallographica Section C-Crystal Structure Communications. 46: 934-936. DOI: 10.1107/S0108270189010772  0.344
1990 Hanessian S, Roy PJ, Petrini M, Hodges PJ, Fabio RD, Carganico G. Synthetic Studies on the Mevinic Acids Using the Chiron Approach: Total Synthesis of (+)-Dihydromevinolin." Journal of Organic Chemistry. 55: 5766-5777. DOI: 10.1021/Jo00309A022  0.392
1990 Hanessian S, Fabio RD, Marcoux JF, Prud'homme M. The synthesis of substituted lactones by intramolecular chirality transfer with stereodifferentiating chiral .alpha.-ester radical intermediates Journal of Organic Chemistry. 55: 3436-3438. DOI: 10.1021/Jo00298A005  0.375
1990 Hanessian S, Desilets D, Bennani YL. A novel ring-closure strategy for the carbapenems: the total synthesis of (+)-thienamycin The Journal of Organic Chemistry. 55: 3098-3103. DOI: 10.1021/Jo00297A026  0.384
1990 Hanessian S, Cooke NG, DeHoff B, Sakito Y. The total synthesis of (+)-ionomycin Journal of the American Chemical Society. 112: 5276-5290. DOI: 10.1021/Ja00169A041  0.409
1990 Hanessian S, Bennani YL. A versatile asymmetric synthesis of α-amino α-alkyl-phosphonic acids of high enantiomeric purity Tetrahedron Letters. 31: 6465-6468. DOI: 10.1016/S0040-4039(00)97092-8  0.361
1990 Hanessian S, Bennani YL, Delorme D. The asymmetric synthesis of α-chloro α-alkyl and α-methyl α-alkyl phosphonic acids of high enantiomeric purity. Tetrahedron Letters. 31: 6461-6464. DOI: 10.1016/S0040-4039(00)97091-6  0.328
1990 Hanessian S, Faucher A, Léger S. Total synthesis of (+)-meroquinene Tetrahedron. 46: 231-243. DOI: 10.1016/S0040-4020(01)97595-7  0.378
1989 Belanger-Gariepy F, Bennani YL, Hanessian S, Brisse F. Structure of a chiral chloropropyl bicyclic phosphonamide Acta Crystallographica Section C-Crystal Structure Communications. 45: 289-291. DOI: 10.1107/S0108270188011138  0.311
1989 Belanger-Gariepy F, Roy P, Hanessian S, Brisse F. Structure of a tricyclic lactone – an important intermediate for the total synthesis of dihydromevinolin Acta Crystallographica Section C-Crystal Structure Communications. 45: 145-148. DOI: 10.1107/S0108270188010285  0.406
1989 Hanessian S, Sakito Y, Dhanoa D, Baptistella L. Synthesis of (+)-palitantin Tetrahedron. 45: 6623-6630. DOI: 10.1016/S0040-4020(01)89132-8  0.398
1989 Hanessian S, Alpegiani M. Highly stereoselective free radical C-6-allylation of penams - synthesis of a noval β-lactamase inhibitor Tetrahedron. 45: 941-950. DOI: 10.1016/0040-4020(89)80006-7  0.319
1987 Hanessian S, Ugolini A, Hodges PJ, Beaulieu P, Dube D, Andre C. Progress in natural product chemistry by the chiron and related approaches - synthesis of avermectin B1a Pure and Applied Chemistry. 59: 299-316. DOI: 10.1351/Pac198759030299  0.335
1987 Hanessian S, Dhanoa DS, Beaulieu PL. Synthesis of carbocycles from ω-substituted α,β-unsaturated esters via radical-induced cyclizations Canadian Journal of Chemistry. 65: 1859-1866. DOI: 10.1139/V87-312  0.394
1987 Hanessian S, Vanasse B. A synthetic strategy for tricholomic acid and acivicin Canadian Journal of Chemistry. 65: 195-199. DOI: 10.1139/V87-031  0.336
1987 Desilets D, Belanger-Gariepy F, Hanessian S, Brisse F. Structure and stereochemistry of a carbapenam derivative Acta Crystallographica Section C-Crystal Structure Communications. 43: 919-922. DOI: 10.1107/S0108270187093570  0.319
1987 Hanessian S, Kagotani M. A Novel Regiospecific Synthesis of 2-Substituted Pyridines Synthesis. 1987: 409-411. DOI: 10.1055/S-1987-27967  0.369
1987 Hanessian S, Botta M. Methodology for the polyene and related antibiotics-versatile and practical access to bifunctional all-trans polyolefinic systems Tetrahedron Letters. 28: 1151-1154. DOI: 10.1016/S0040-4039(00)95312-7  0.322
1987 Hanessian S, Sahoo SP, Botta M. Methodology fro the polyene and related antibiotics--enantiospecific synthesis of chiral structural units of amphotericin B from A common progenior: the C1–C13 polyol segment Tetrahedron Letters. 28: 1143-1146. DOI: 10.1016/S0040-4039(00)95310-3  0.375
1987 Hanessian S, Murray P. Stereochemical control of nature's biosynthetic pathways:A general strategy for the synthesis 0f polypropionate-derived structural units from a single chiral progenitor Tetrahedron. 43: 5055-5072. DOI: 10.1016/S0040-4020(01)87683-3  0.409
1986 Hanessian S, Murray PJ. A highly convergent and enantiospecific synthesis of acyclic subunits of ionomycin from a single chiral progenitor Canadian Journal of Chemistry. 64: 2232-2234. DOI: 10.1139/V86-368  0.377
1986 Bedeschi A, Bélanger-Gariépy F, Hanessian S, Brisse F. Structure and absolute configuration of a penam derivative Acta Crystallographica Section C-Crystal Structure Communications. 42: 442-445. DOI: 10.1107/S0108270186095859  0.35
1986 Belanger-Gariepy F, Delorme D, Hanessian S, Brisse F. The structures of two chiral bicyclic phosphonamides Acta Crystallographica Section C-Crystal Structure Communications. 42: 856-860. DOI: 10.1107/S0108270186094295  0.319
1986 Hanessian S, Hodges PJ, Murray PJ, Sahoo SP. Mild and efficient preparation of γ-substituted α,β-unsturated γ-butyrolactones from epoxides Journal of the Chemical Society, Chemical Communications. 754-755. DOI: 10.1039/C39860000754  0.313
1986 Hanessian S, Beaulieu P, Dubé D. A novel synthetic route to the hexahydrobenzofuran subunit of the avermectins and milbemycins Tetrahedron Letters. 27: 5071-5074. DOI: 10.1016/S0040-4039(00)85135-7  0.357
1986 Hanessian S, Hodges PJ, Sahoo SP, Roy PJ. The Use of 3‐Phenylselenobutanal as a Crotonaldehyde Equivalent in Synthesis. Tetrahedron Letters. 27: 2949-2952. DOI: 10.1016/S0040-4039(00)84687-0  0.31
1986 Hanessian S, Ugolini A, Dube D, Hodges PJ, Andre C. Synthesis of (+)-avermectin B1a Journal of the American Chemical Society. 108: 2776-2778. DOI: 10.1002/Chin.198637328  0.408
1986 Hanessian S, Kloss J, Sugawara T. Stereocontrolled access to the octosyl acids - total synthesis of octosyl acid A Journal of the American Chemical Society. 108: 2758-2759. DOI: 10.1002/Chin.198637321  0.326
1986 Hanessian S, Guindon Y, Lavallee P, Dextraze P. Total Synthesis of 11‐Oxaprostaglandin F2α and F2β. Cheminform. 17. DOI: 10.1002/Chin.198606321  0.649
1985 Hanessian S, Couture C, Wyss H. Design and reactivity of organic functional groups—utility of imidazolylsulfonates in the synthesis of monobactams and 3-amino nocardicinic acid Canadian Journal of Chemistry. 63: 3613-3617. DOI: 10.1139/V85-593  0.387
1985 Hanessian S, Roy R. Chemistry of spectinomycin: its total synthesis, stereocontrolled rearrangement, and analogs Canadian Journal of Chemistry. 63: 163-172. DOI: 10.1139/V85-026  0.433
1985 Hanessian S, Sahoo SP, Murray PJ. A tactically novel alternative to acyclic stereoselection based on the concept of a replicating chiron — access to 1,3-polyols Tetrahedron Letters. 26: 5631-5634. DOI: 10.1016/S0040-4039(01)80905-9  0.337
1985 Hanessian S, Murray PJ, Sahoo SP. A tactically novel alternative to acyclic stereoselection based on the concept of a replicating chiron - 1,5-C-methyl substitution Tetrahedron Letters. 26: 5623-5626. DOI: 10.1016/S0040-4039(01)80903-5  0.33
1985 Hanessian S, Kloss J. Total synthesis of biologically important amino sugars via thenitroaldol reaction Tetrahedron Letters. 26: 1261-1264. DOI: 10.1016/S0040-4039(00)94865-2  0.343
1985 Hanessian S, Guindon Y, Lavallée P, Dextraze P. Total synthesis of 11-oxaprostaglandin F2α and F2β Carbohydrate Research. 141: 221-238. DOI: 10.1016/S0008-6215(00)90454-3  0.646
1985 Hanessian S, Bedeschi A, Battistini C, Mongelli N. Novel synthetic approaches to the penems: total synthesis of Penem FCE 22101 Cheminform. 17: 43-49. DOI: 10.1002/Chin.198619358  0.362
1985 Hanessian S, Hoornaert C, Pernet AG, Nadzan AM. Design and synthesis of potential megacaloric parenteral nutrients Carbohydrate Research. 137: C14-C16. DOI: 10.1002/Chin.198535317  0.321
1984 Hanessian S, Ugolini A, Dubé D, Glamyan A. Facile access to (S)-1,2,4-butanetriol and its derivatives Canadian Journal of Chemistry. 62: 2146-2147. DOI: 10.1139/V84-367  0.348
1984 Hanessian S, Sahoo SP. Synthetic approaches to β-lactam antibiotics: a stereocontrolled synthesis of trans 3-(S)-amino-4-(S)-ethyl-2-oxo-1-azetidine Canadian Journal of Chemistry. 62: 1400-1402. DOI: 10.1139/V84-237  0.406
1984 Hanessian S, Delorme D, Beaudoin S, LeBlanc Y. Additions and Corrections - Design and Reactivity of Topologically Unique, Chiral Phosphonamides. Remarkable Diastereofacial Selectivity in Asymmetric Olefination and Alkylation. Journal of the American Chemical Society. 106: 8330-8330. DOI: 10.1021/Ja00338A602  0.321
1984 Hanessian S, Delorme D, Beaudoin S, Leblanc Y. Design and reactivity of topologically unique, chiral phosphonamides. Remarkable diastereofacial selectivity in asymmetric olefination and alkylation Journal of the American Chemical Society. 106: 5754-5756. DOI: 10.1021/Ja00331A070  0.318
1984 Hanessian S, Delorme D, Dufresne Y. Mild cleavage of methoxymethyl (MOM) ethers with trimethylsilyl bromide Tetrahedron Letters. 25: 2515-2518. DOI: 10.1016/S0040-4039(01)81219-3  0.328
1984 Hanessian S, Sahoo SP. A novel and efficient synthesis of L-vinylglycine Tetrahedron Letters. 25: 1425-1428. DOI: 10.1016/S0040-4039(01)80177-5  0.366
1984 Hanessian S, Ugolini A. Synthesis of a chiral 1,7-dioxaspiro[5,5]undecene. A model for the spiroacetal subunit of avermectin B1a Carbohydrate Research. 130: 261-269. DOI: 10.1002/Chin.198449312  0.357
1983 Hanessian S, Delorme D, Tyler PC, Demailly G, Chapleur Y. Total synthesis of the C-3 – C-17 segment of boromycin Canadian Journal of Chemistry. 61: 634-637. DOI: 10.1139/V83-115  0.324
1983 Hanessian S, Ugolini A, Therien M. Stereocontrolled synthesis of the spiro ketal unit of avermectin B1a aglycon Journal of Organic Chemistry. 48: 4427-4430. DOI: 10.1021/Jo00171A065  0.39
1983 HANESSIAN S, DELORME D, TYLER PC, DEMAILLY G, CHAPLEUR Y. ChemInform Abstract: Carbohydrates as "Chiral Templates" in Organic Synthesis - Target: Boromycin (33 Literaturzitate). Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198343363  0.341
1983 Hanessian S, Desilets D, Rancourt G, Fortin R. The Total, Stereocontrolled Synthesis Of A Chemical Precursor To (+)-Thienamycin. A Formal Synthesis Of The Antibiotic Cheminform. 14. DOI: 10.1002/Chin.198302352  0.415
1982 Hanessian S, Desilets D, Rancourt G, Fortin R. The total, stereocontrolled synthesis of a chemical precursor to (+)-thienamycin. A formal synthesis of the antibiotic Canadian Journal of Chemistry. 60: 2292-2294. DOI: 10.1139/V82-327  0.426
1982 Hanessian S, Pougny JR, Boessenkool IK. Total synthesis of the C19-C29 aliphatic segment of (+)-rifamycin S - A formal synthesis of the antibiotic Journal of the American Chemical Society. 104: 6164-6166. DOI: 10.1021/Ja00386A076  0.349
1982 Hanessian S, Leblanc Y, Lavallée P. Design and reactivity of organic functional groups: the highly crystalline 2-alkoxy N,N′-diphenyl-1,3,2-diazaphospholanes and their facile conversion into alkyl halides Tetrahedron Letters. 23: 4411-4414. DOI: 10.1016/S0040-4039(00)85615-4  0.345
1982 Hanessian S, Demailly G, Chapleur Y, Leger S. Facile Access To Chiral 5-Hydroxy-2-Methylhexanoic Acid Lactones (Pheromones Of The Carpenter Bee) Cheminform. 13. DOI: 10.1002/Chin.198212251  0.332
1982 HANESSIAN S, TYLER PC, DEMAILLY G, CHAPLEUR Y. ChemInform Abstract: TOTAL SYNTHESIS AND STEREOCHEMICAL IDENTITY OF THE C18H32O5 DEGRADATION PRODUCT FROM BOROMYCIN Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198203309  0.364
1981 Hanessian S, Roy R, Therien M, Delorme D. Synthesis of 4-amino-4-(S)-dihydrospectinomycin Journal of Antibiotics. 34: 350-352. PMID 6456250 DOI: 10.7164/Antibiotics.34.350  0.359
1981 Hanessian S, Dixit DM, Liak TJ. Studies directed toward the total synthesis of the ezomycins, the octosyl acids and related antibiotics Pure and Applied Chemistry. 53: 129-148. DOI: 10.1351/Pac198153010129  0.368
1981 Hanessian S, Demailly G, Chapleur Y, Leger S. Facile access to chiral 5-hydroxy-2-methylhexanoic acid lactones (pheromones of the carpenter Bee) Journal of the Chemical Society, Chemical Communications. 1125-1126. DOI: 10.1039/C39810001125  0.363
1981 Hanessian S, Tyler PC, Demailly G, Chapleur Y. Total synthesis and stereochemical identity of the C18H32O5 degradation product from boromycin Journal of the American Chemical Society. 103: 6243-6246. DOI: 10.1021/Ja00410A056  0.356
1981 Hanessian S, Tyler PC, Chapleur Y. Reaction of lithium dimethylcuprate with conformationally biased β-acyloxy enol esters - regio and stereocontrolled access to functionalized six-carbon chiral synthons Tetrahedron Letters. 22: 4583-4586. DOI: 10.1016/S0040-4039(01)82987-7  0.365
1981 Hanessian S, Roy R. A stereocontrolled rearrangement of spectinomycin - the stereochemical identity of spectinoic acid Tetrahedron Letters. 22: 1005-1008. DOI: 10.1016/S0040-4039(01)82851-3  0.338
1981 Hanessian S, Jiam Liak T, Dixit DM. Synthesis of trans-fused perhydrofuropyrans and related α-methylene lactones: bicyclic ring-systems present in the ezomycins, the octosyl acids, and certain antitumor terpenoids Carbohydrate Research. 88: C14-C19. DOI: 10.1016/S0008-6215(00)84618-2  0.373
1981 Hanessian S, Lavallee P. Total synthesis of (+)-thromboxane B2 from D-glucose. A detailed account Canadian Journal of Chemistry. 59: 870-877. DOI: 10.1002/Chin.198130350  0.32
1980 Steliou K, Szczygielska-Nowosielska A, Favre A, Poupart MA, Hanessian S. Reagents for organic synthesis: use of organostannyl oxides as catalytic neutral esterification agents in the preparation of macrolides Journal of the American Chemical Society. 102: 7578-7579. DOI: 10.1021/Ja00545A038  0.31
1980 Hanessian S, Guindon Y. Cleavage of methyl and benzyl ethers with thiotrimethylsilanes Tetrahedron Letters. 21: 2305-2308. DOI: 10.1016/S0040-4039(00)92591-7  0.591
1980 Hanessian S, Guindon Y. Chemistry of the glycosidic linkage. Direct conversion of glycosides into 1-thioglycosides by use of [alkyl(or aryl)thio]trimethylsilanes Carbohydrate Research. 86: C3-C6. DOI: 10.1016/S0008-6215(00)85913-3  0.603
1979 Hanessian S, Roy R. Synthesis of (+)-spectinomycin Journal of the American Chemical Society. 101: 5839-5841. DOI: 10.1021/Ja00513A070  0.414
1979 Hanessian S. Approaches to the total synthesis of natural products using "chiral templates" derived from carbohydrates Accounts of Chemical Research. 10: 159-165. DOI: 10.1021/Ar50137A001  0.382
1979 Hanessian S, Frenette R. Total stereospecific synthesis of (+) azimic and (+) carpamic acids from D-glucose Tetrahedron Letters. 20: 3391-3394. DOI: 10.1016/S0040-4039(01)95417-6  0.337
1978 Hanessian S, Massé R, Capmeau ML. Aminoglycoside antibiotics: synthesis of 5''-amino-5''-deoxyneomycin and 5''-amino-5''-deoxyparomomycin. The Journal of Antibiotics. 30: 893-6. PMID 591451 DOI: 10.7164/Antibiotics.30.893  0.363
1978 Hanessian S, Rancourt G, Guindon Y. Assembly of the carbon skeletal framework of erythronolide A Canadian Journal of Chemistry. 56: 1843-1846. DOI: 10.1139/V78-299  0.586
1978 Hanessian S, Massé R, Nakagawa T. Aminoglycoside antibiotics: Studies directed toward the selective modification of hydroxyl groups: Synthesis of 3′-epiparomamine and 3′-epineamine Canadian Journal of Chemistry. 56: 1509-1517. DOI: 10.1139/V78-245  0.388
1978 Hanessian S, Massé R, Ekborg G. Aminoglycoside antibiotics: The formation and characterization of dihydrooxazine derivatives in the paromomycin series Canadian Journal of Chemistry. 56: 1492-1499. DOI: 10.1139/V78-243  0.345
1978 Hanessian S, Bargiotti A, LaRue M. A mild and stereospecific conversion of vicinal diols into olefins Tetrahedron Letters. 19: 737-740. DOI: 10.1016/S0040-4039(01)85381-8  0.321
1978 Hanessian S, Masse R, Ekborg G. Aminoglycoside Antibiotics‐ The Formation And Characterization Of Dihydrooxazine Derivatives In The Paromomycin Series Cheminform. 9. DOI: 10.1002/Chin.197840333  0.309
1978 Hanessian S, Takamoto T, Massé R, Patil G. Aminoglycoside antibiotics: Chemical conversion of neomycin B, paromomycin, and lividomycin B into bioactive pseudosaccharides Canadian Journal of Chemistry. 56: 1482-1491. DOI: 10.1002/Chin.197840332  0.305
1978 Hanessian S, Masse R, Nakagawa T. Aminoglycoside Antibiotics: Studies Directed Toward The Selective Modification Of Hydroxyl Groups: Synthesis Of 3′‐Epiparomamine And 3′‐Epineamine Cheminform. 9. DOI: 10.1002/Chin.197840322  0.366
1978 Hanessian S, Ogawa T, Takamoto T. Aminoglycoside antibiotics: Synthesis of pseudotrisaccharides derived from neamine and paromamine Canadian Journal of Chemistry. 56: 1500-1508. DOI: 10.1002/Chin.197840321  0.345
1977 Arcamone F, Penco S, Redaelli S, Hanessian S. Synthesis and antitumor activity of 4'-deoxydaunorubicin and 4'-deoxyadriamycin. Journal of Medicinal Chemistry. 19: 1424-5. PMID 1003430 DOI: 10.1021/Jm00234A016  0.372
1977 Bargiotti A, Cassinelli G, Franchi G, Gioia B, Lazzari E, Redaelli S, Vigevani A, Arcamone F, Hanessian S. Synthesis of derivatives of 3-amino-2,3-dideoxy-l-hexoses related to daunosamine (3-amino-2,3,6-trideoxy-l-lyxo-hexose) Carbohydrate Research. 58: 353-361. PMID 912692 DOI: 10.1016/S0008-6215(00)84362-1  0.314
1977 Hanessian S, Pernet AG. Synthesis of naturally occurring C-nucleosides, their analogs, and functionalized C-glycosyl precursors. Advances in Carbohydrate Chemistry and Biochemistry. 33: 111-88. PMID 793324 DOI: 10.1016/S0065-2318(08)60281-4  0.348
1977 Hanessian S, Rancourt G. Approaches to the total synthesis of natural products from carbohydrates Pure and Applied Chemistry. 49: 1201-1214. DOI: 10.1351/Pac197749081201  0.387
1977 Hanessian S, Rancourt G. Carbohydrates as chiral intermediates in organic synthesis. Two functionalized chemical precursors comprising eight of the ten chiral centers of erythronolide A Canadian Journal of Chemistry. 55: 1111-1113. DOI: 10.1139/V77-155  0.368
1977 Hanessian S, Lavallee P. A stereospecifie, total synthesis of thromboxane B2 Canadian Journal of Chemistry. 55: 562-565. DOI: 10.1139/V77-079  0.331
1977 Hanessian S, Banoub J. Chemistry of the glycosidic linkage. An efficient synthesis of 1,2-trans-di-saccharides Carbohydrate Research. 53. DOI: 10.1016/S0008-6215(00)85468-3  0.397
1977 Hanessian S, Masse R. Photochemical cleavage of theN-(benzyloxycarbonyl) group in amino sugar derivatives Carbohydrate Research. 54: 142-144. DOI: 10.1016/S0008-6215(00)80563-7  0.31
1977 Arcamone F, Penco S, Redaelli S, Hanessian S. Synthesis And Antitumor Activity Of 4′-Deoxydaunorubicin And 4′-Deoxyadriamycin Cheminform. 8. DOI: 10.1002/Chin.197715379  0.382
1976 Arcamone F, Bargiotii A, Cassinelli G, Redaelli S, Hanessian S, Di Marco A, Casazza AM, Dasdia T, Necco A, Reggiani P, Supino R. Stereocontrolled glycosidation of daunomycinone. Synthesis and biological evaluation of 6-hydroxy-L-arabino analogues of antitumor anthracyclines. Journal of Medicinal Chemistry. 19: 733-4. PMID 1271420 DOI: 10.1002/Chin.197640373  0.354
1976 Arcamone F, Bargiotti A, Cassinelli G, Penco S, Hanessian S. Synthesis of a configurational analog of daunorubicin. Carbohydrate Research. 46: C3-5. PMID 1260787 DOI: 10.1016/S0008-6215(00)84305-0  0.422
1976 Hanessian S, Banoub J. Chemistry of the glycosidic linkage. Lewis acid catalyzed glycosidations with amide acetals and lactim ethers. Tetrahedron Letters. 17: 657-660. DOI: 10.1016/S0040-4039(00)74589-8  0.347
1976 HANESSIAN S, LAVALLEE P. ChemInform Abstract: PREPARATION AND SYNTHETIC UTILITY OF TERT-BUTYLDIPHENYLSILYL ETHERS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197613286  0.367
1975 Hanessian S, Lavallee P. The Preparation and Synthetic Utility of tert-Butyldiphenylsilyl Ethers Canadian Journal of Chemistry. 53: 2975-2977. DOI: 10.1139/V75-419  0.356
1975 Hanessian S, Cassinelli G, Casey M. Chemistry of the glycosidic linkage. 2-Alkoxy-3-(p-nitrobenzoyl)-2-phenyl-4,5-[α-D-glucopyrano]-2-oxazolidines, a new class of carbohydrate 1,2-ortho-acid derivative Carbohydrate Research. 44: C18-C21. DOI: 10.1016/S0008-6215(00)84181-6  0.319
1975 hanessian S, Banoub J. Chemistry of the glycosidic linkage. A rapid and efficient synthesis of carbohydrate 1,2-orthoesters Carbohydrate Research. 44: C14-C17. DOI: 10.1016/S0008-6215(00)84180-4  0.378
1975 HANESSIAN S, DEXTRAZE P, FOUGEROUSSE A, GUINDON Y. ChemInform Abstract: STERISCH KONTROLLIERTE SYNTHESE VON CHIRALEN VORLAEUFERN DER 11-OXAPROSTAGLANDINE Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197506458  0.606
1974 Hanessian S, Masse R. Synthetic approaches to kasugamine. Carbohydrate Research. 35: 175-85. PMID 4854593 DOI: 10.1016/S0008-6215(00)84844-2  0.353
1974 Hanessian S, Pernet AG. Carbanions in Carbohydrate Chemistry: Approaches to Chemical Precursors of C-Nucleosides Canadian Journal of Chemistry. 52: 1280-1293. DOI: 10.1139/V74-198  0.345
1974 Hanessian S, Pernet AG. Carbanions in Carbohydrate Chemistry: Synthesis of C-Glycosyl Malonates Canadian Journal of Chemistry. 52: 1266-1279. DOI: 10.1139/V74-197  0.314
1974 Hanessian S, Staub APA. Elimination, Oxidation, and Transposition Reactions in Conformationally Biased Carbohydrates: Methyl 4,6-O-Benzylidene-α-D-Altropyranosides Containing the Phenylthio Group Canadian Journal of Chemistry. 52: 1258-1265. DOI: 10.1139/V74-196  0.333
1974 Ogawa T, Takamoto T, Hanessian S. Aminoglycoside antibiotics: synthesis of 6-0-(β-D-ribofuranosyl) paromamine Tetrahedron Letters. 15: 4013-4016. DOI: 10.1016/S0040-4039(01)92071-4  0.315
1974 Hanessian S, Dextraze P, Fougerousse A, Guindon Y. Synthese stereocontrolee des precurseurs chiraux des 11-oxaprostaglandines Tetrahedron Letters. 15: 3983-3986. DOI: 10.1016/S0040-4039(01)92063-5  0.555
1974 Hanessian S, Ogawa T, Guindon Y, Kamennof JL, Roy R. Utilization of functionalized polymers in synthesis: immobilization of carbohydrates as acetals, and some chemical transformations Carbohydrate Research. 38: C15-C18. DOI: 10.1016/S0008-6215(00)82382-4  0.577
1974 Hanessian S, Ogawa T, Guindon Y. Facile access to ethyl 2-C-β-D-ribofuranosylacetates Carbohydrate Research. 38: C12-C14. DOI: 10.1016/S0008-6215(00)82381-2  0.562
1974 HANESSIAN S, PERNET AG. ChemInform Abstract: PREPARATIVE AND EXPLORATORY CARBOHYDRATE CHEMISTRY. CARBANIONS IN CARBOHYDRATE CHEMISTRY, APPROACHES TO CHEMICAL PRECURSORS OF C-NUCLEOSIDES Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197429424  0.316
1974 HANESSIAN S, PERNET AG. ChemInform Abstract: PREPARATIVE AND EXPLORATORY CARBOHYDRATE CHEMISTRY. CARBANIONS IN CARBOHYDRATE CHEMISTRY, SYNTHESIS OF C-GLYCOSYL MALONATES Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197429423  0.389
1973 Hanessian S, Lavallee P. Synthesis of 6-amino-6-deoxy- , -trehalose: a positional isomer of trehalosamine. The Journal of Antibiotics. 25: 683-4. PMID 4647840 DOI: 10.7164/Antibiotics.25.683  0.381
1973 Hanessian S, Lavallee P, Pernet AG. A new synthesis of methylene acetals Carbohydrate Research. 26: 258-260. DOI: 10.1016/S0008-6215(00)85050-8  0.388
1973 Hanessian S, Lavallée P. Selective substitution reactions of α,α-trehalose: preparation of 6-monofunctional derivatives Carbohydrate Research. 28: 303-311. DOI: 10.1016/S0008-6215(00)82785-8  0.307
1972 Hanessian S, Ponpipom M, Lavallee P. Procedures for the direct replacement of primary hydroxyl groups in carbohydrates by halogen Carbohydrate Research. 24: 45-56. DOI: 10.1016/S0008-6215(00)82258-2  0.329
1971 Butterworth RF, Hanessian S. Methyl 2,3-O-Isopropylidene-β-D-ribo-pentodialdofuranoside: a Useful Intermediate in Chain Extension Reactions Canadian Journal of Chemistry. 49: 2755-2759. DOI: 10.1139/V71-458  0.307
1971 Hanessian S, Moralioglu E. Chemistry of 1-(dimethylamino)ethylidene and α-(dimethylamino)benzylidene acetals: utility as blocking group for diols and for selective esterification. Tetrahedron Letters. 12: 813-816. DOI: 10.1016/S0040-4039(01)96563-3  0.31
1971 Ponpipom M, Hanessian S. Novel access to 2′-deoxyuridine, and reactive intermediates to pyrimidine nucleosides Carbohydrate Research. 17: 248-251. DOI: 10.1016/S0008-6215(00)81569-4  0.358
1971 Hanessian S, Staub APA. Synthesis of carbohydrate derivatives containing vinylic thioether groups1 Carbohydrate Research. 16: 419-433. DOI: 10.1016/S0008-6215(00)81177-5  0.328
1969 Hanessian S, Schütze G. Synthetic penicillins derived from cycloheptatrienecarboxylic acids. Journal of Medicinal Chemistry. 12: 527-9. PMID 5788175 DOI: 10.1021/Jm00303A614  0.313
1969 Hanessian S, Schütze G. Synthetic penicillins derived from benznorcaradienecarboxylic acids. Journal of Medicinal Chemistry. 12: 529-31. PMID 4892245 DOI: 10.1021/Jm00303A615  0.313
1969 Hanessian S, Plessas NR. Reactions of carbohydrates with (halomethylene)dimethyliminium halides and related reagents. Synthesis of some chlorodeoxy sugars Journal of Organic Chemistry. 34: 2163-2170. DOI: 10.1021/Jo01259A030  0.35
1969 Hanessian S, Plessas NR. Reaction of O-benzylidene sugars with N-bromosuccinimide. III. Applications to the synthesis of aminodeoxy and deoxy sugars of biological importance The Journal of Organic Chemistry. 34: 1045-1053. DOI: 10.1021/Jo01256A060  0.312
1969 Hanessian S. Sugar lactams. III. Synthesis of five-,six-, and seven-membered analogs Journal of Organic Chemistry. 34: 675-681. DOI: 10.1021/Jo01255A042  0.395
1967 Hanessian S. Neighboring-group participation across a furanose ring. Synthesis of 5-acetamido-5-deoxy-D-lyxopyranose from D-arabinose precursors The Journal of Organic Chemistry. 32: 163-168. DOI: 10.1021/Jo01277A040  0.315
1966 Hanessian S, Kaltenbronn JS. Synthesis of a Bromine-Rich Marine Antibiotic Journal of the American Chemical Society. 88: 4509-4510. DOI: 10.1021/Ja00971A039  0.391
1965 Hanessian S, Haskell TH. Synthesis and Characterization of 3,6-Diamino-3,6-dideoxy-D-idose1 The Journal of Organic Chemistry. 30: 1080-1085. DOI: 10.1021/Jo01015A030  0.332
1963 Hanessian S, Haskell TH. Synthesis of 5-Acetamido-5-deoxypentoses. Sugar Derivatives Containing Nitrogen in the Ring1 The Journal of Organic Chemistry. 28: 2604-2610. DOI: 10.1021/Jo01045A029  0.402
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