Samuel H. Gellman - Publications

Affiliations: 
Chemistry University of Wisconsin, Madison, Madison, WI 
Area:
biologically active polymers
Website:
https://www.chem.wisc.edu/users/gellman

278 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Liu S, Jean-Alphonse FG, White AD, Wootten D, Sexton PM, Gardella TJ, Vilardaga JP, Gellman SH. Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. Journal of the American Chemical Society. PMID 31496241 DOI: 10.1021/jacs.9b04179  0.56
2019 Cheloha RW, Woodham AW, Bousbaine D, Wang T, Liu S, Sidney J, Sette A, Gellman SH, Ploegh HL. Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids. Journal of Immunology (Baltimore, Md. : 1950). PMID 31391235 DOI: 10.4049/jimmunol.1900536  0.44
2019 Wang J, Cary BP, Beyer PD, Gellman SH, Weix DJ. Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters. Angewandte Chemie (International Ed. in English). PMID 31287943 DOI: 10.1002/anie.201906000  0.52
2019 Outlaw VK, Bottom-Tanzer S, Kreitler DF, Gellman SH, Porotto M, Moscona A. Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent. Journal of the American Chemical Society. PMID 31268705 DOI: 10.1021/jacs.9b04615  0.72
2019 Cary BP, Hager MV, Gellman SH. Impact of substitution registry on receptor-activation profiles of backbone-modified glucagon-like peptide-1 analogues. Chembiochem : a European Journal of Chemical Biology. PMID 31172641 DOI: 10.1002/cbic.201900300  0.56
2019 Kurgan KW, Kleman AF, Bingman CA, Kreitler DF, Weisblum B, Forest KT, Gellman SH. Retention of Native Quaternary Structure in Racemic Melittin Crystals. Journal of the American Chemical Society. PMID 31059253 DOI: 10.1021/jacs.9b02691  0.92
2019 Yao Z, Cary BP, Bingman CA, Wang C, Kreitler DF, Satyshur KA, Forest KT, Gellman SH. Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin α3 Toxicity. Journal of the American Chemical Society. PMID 31045358 DOI: 10.1021/jacs.9b00349  1
2019 Kreitler DF, Yao Z, Steinkruger JD, Mortenson DE, Huang L, Mittal R, Travis BR, Forest KT, Gellman SH. A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. Journal of the American Chemical Society. PMID 30645104 DOI: 10.1021/jacs.8b11246  0.96
2018 Liu S, Cheloha RW, Watanabe T, Gardella TJ, Gellman SH. Receptor selectivity from minimal backbone modification of a polypeptide agonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 30442659 DOI: 10.1073/pnas.1815294115  0.44
2018 Eddinger GA, Gellman SH. Differential Effects of β³- vs. β²-Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides. Angewandte Chemie (International Ed. in English). PMID 30161284 DOI: 10.1002/anie.201806909  0.36
2018 Fisher BF, Hong SH, Gellman SH. Thermodynamic Scale of β-Amino Acid Residue Propensities for an α-Helix-like Conformation. Journal of the American Chemical Society. PMID 30022665 DOI: 10.1021/jacs.8b05162  0.36
2018 Shin YH, Gellman SH. Impact of Backbone Pattern and Residue Substitution on Helicity in α/β/γ-Peptides. Journal of the American Chemical Society. PMID 29350033 DOI: 10.1021/jacs.7b10868  0.88
2017 Mortenson DE, Kreitler DF, Thomas NC, Guzei IA, Gellman SH, Forest KT. Evaluation of β-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure. Chembiochem : a European Journal of Chemical Biology. PMID 29272560 DOI: 10.1002/cbic.201700580  0.88
2017 Wang C, Ma CD, Yeon H, Wang X, Gellman SH, Abbott NL. Non-Additive Interactions Mediated by Water at Chemically Heterogeneous Surfaces: Non-ionic Polar Groups and Hydrophobic Interactions. Journal of the American Chemical Society. PMID 29129065 DOI: 10.1021/jacs.7b08367  1
2017 Thomas NC, Bartlett GJ, Woolfson DN, Gellman SH. Toward a Soluble Model System for the Amyloid State. Journal of the American Chemical Society. PMID 29116774 DOI: 10.1021/jacs.7b07225  0.52
2017 Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Incorporation of β-peptides enhances the antifungal activity and selectivity of the helical antimicrobial peptide aurein 1.2. Acs Chemical Biology. PMID 29091404 DOI: 10.1021/acschembio.7b00843  0.8
2017 Cheloha RW, Chen B, Kumar NN, Watanabe T, Thorne RG, Li L, Gardella TJ, Gellman SH. Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution. Journal of Medicinal Chemistry. PMID 29064243 DOI: 10.1021/acs.jmedchem.7b00876  0.44
2017 Fisher BF, Hong SH, Gellman SH. Helix Propensities of Amino Acid Residues via Thioester Exchange. Journal of the American Chemical Society. PMID 28898059 DOI: 10.1021/jacs.7b07930  0.36
2017 Rank LA, Walsh NM, Liu R, Lim FY, Bok JW, Huang M, Keller NP, Gellman SH, Hull CM. A cationic polymer that shows high antifungal activity against diverse human pathogens. Antimicrobial Agents and Chemotherapy. PMID 28739790 DOI: 10.1128/AAC.00204-17  0.64
2017 Hager MV, Clydesdale L, Gellman SH, Sexton PM, Wootten D. Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1. Biochemical Pharmacology. PMID 28363772 DOI: 10.1016/j.bcp.2017.03.018  0.56
2016 Checco JW, Gellman SH. Iterative non-proteinogenic residue incorporation yields α/β-peptides with a helix-loop-helix tertiary structure and high affinity for VEGF. Chembiochem : a European Journal of Chemical Biology. PMID 27897370 DOI: 10.1002/cbic.201600545  1
2016 Hager MV, Johnson LM, Wootten D, Sexton PM, Gellman SH. β-Arrestin-Biased Agonists of the GLP-1 Receptor from β-Amino Acid Residue Incorporation into GLP-1 Analogues. Journal of the American Chemical Society. PMID 27813409 DOI: 10.1021/jacs.6b08323  1
2016 Walsh PS, Blodgett KN, McBurney C, Gellman SH, Zwier TS. Inherent Conformational Preferences of Ac-Gln-Gln-NHBn: Sidechain Hydrogen Bonding Supports a β-Turn in the Gas Phase. Angewandte Chemie (International Ed. in English). PMID 27775204 DOI: 10.1002/anie.201607842  0.44
2016 Cheloha RW, Watanabe T, Dean T, Gellman SH, Gardella TJ. Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse Agonist. Acs Chemical Biology. PMID 27533344 DOI: 10.1021/acschembio.6b00404  0.44
2016 Fisher BF, Gellman SH. Impact of γ-Amino Acid Residue Preorganization on α/γ-Peptide Foldamer Helicity in Aqueous Solution. Journal of the American Chemical Society. PMID 27529788 DOI: 10.1021/jacs.6b06177  0.36
2016 MacDonald MJ, Lavis LD, Hilvert D, Gellman SH. Evaluation of the Ser-His Dipeptide, a Putative Catalyst of Amide and Ester Hydrolysis. Organic Letters. PMID 27400366 DOI: 10.1021/acs.orglett.6b01279  0.72
2016 Checco JW, Gellman SH. Targeting recognition surfaces on natural proteins with peptidic foldamers. Current Opinion in Structural Biology. 39: 96-105. PMID 27390896 DOI: 10.1016/j.sbi.2016.06.014  1
2016 Kreitler DF, Mortenson DE, Forest KT, Gellman SH. Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. Journal of the American Chemical Society. PMID 27171550 DOI: 10.1021/jacs.6b01454  1
2016 Walsh PS, Dean JC, McBurney C, Kang H, Gellman SH, Zwier TS. Conformation-specific spectroscopy of capped glutamine-containing peptides: role of a single glutamine residue on peptide backbone preferences. Physical Chemistry Chemical Physics : Pccp. PMID 27054830 DOI: 10.1039/c6cp01062h  1
2016 Ma CD, Acevedo-Vélez C, Wang C, Gellman SH, Abbott NL. Interaction of the Hydrophobic Tip of an Atomic Force Microscope with Oligopeptides Immobilized using Short and Long Tethers. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 26895750 DOI: 10.1021/acs.langmuir.5b04618  1
2015 Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC. Single-cell, Time-resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live E. coli. Acs Chemical Biology. PMID 26493221 DOI: 10.1021/acschembio.5b00547  1
2015 Mortenson DE, Steinkruger JD, Kreitler DF, Perroni DV, Sorenson GP, Huang L, Mittal R, Yun HG, Travis BR, Mahanthappa MK, Forest KT, Gellman SH. High-resolution structures of a heterochiral coiled coil. Proceedings of the National Academy of Sciences of the United States of America. PMID 26460035 DOI: 10.1073/pnas.1507918112  1
2015 Kung VM, Cornilescu G, Gellman SH. Impact of Strand Number on Parallel β-Sheet Stability. Angewandte Chemie (International Ed. in English). PMID 26457984 DOI: 10.1002/anie.201506448  1
2015 Hayouka Z, Thomas NC, Mortenson DE, Satyshur KA, Weisblum B, Forest KT, Gellman SH. Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. Journal of the American Chemical Society. 137: 11884-7. PMID 26369301 DOI: 10.1021/jacs.5b07206  1
2015 Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, Eller CH, Raines RT, Murphy WL, Smith BJ, Gellman SH, et al. α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells. Journal of the American Chemical Society. 137: 11365-75. PMID 26317395 DOI: 10.1021/jacs.5b05896  1
2015 Cheloha RW, Gellman SH, Vilardaga JP, Gardella TJ. PTH receptor-1 signalling-mechanistic insights and therapeutic prospects. Nature Reviews. Endocrinology. PMID 26303600 DOI: 10.1038/nrendo.2015.139  1
2015 Hovakeemian SG, Liu R, Gellman SH, Heerklotz H. Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents. Soft Matter. 11: 6840-51. PMID 26234884 DOI: 10.1039/c5sm01521a  1
2015 Fisher BF, Guo L, Dolinar BS, Guzei IA, Gellman SH. Heterogeneous h-bonding in a foldamer helix. Journal of the American Chemical Society. 137: 6484-7. PMID 25974390 DOI: 10.1021/jacs.5b03382  1
2015 Peterson-Kaufman KJ, Haase HS, Boersma MD, Lee EF, Fairlie WD, Gellman SH. Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics. Acs Chemical Biology. PMID 25946900 DOI: 10.1021/acschembio.5b00109  1
2015 Demizu Y, Oba M, Okitsu K, Yamashita H, Misawa T, Tanaka M, Kurihara M, Gellman SH. A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides. Organic & Biomolecular Chemistry. 13: 5617-20. PMID 25897867 DOI: 10.1039/c5ob00389j  1
2015 Checco JW, Kreitler DF, Thomas NC, Belair DG, Rettko NJ, Murphy WL, Forest KT, Gellman SH. Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold. Proceedings of the National Academy of Sciences of the United States of America. 112: 4552-7. PMID 25825775 DOI: 10.1073/pnas.1420380112  1
2015 Liu R, Chen X, Falk SP, Masters KS, Weisblum B, Gellman SH. Nylon-3 polymers active against drug-resistant Candida albicans biofilms. Journal of the American Chemical Society. 137: 2183-6. PMID 25650957 DOI: 10.1021/ja512567y  1
2015 Ma CD, Wang C, Acevedo-Vélez C, Gellman SH, Abbott NL. Modulation of hydrophobic interactions by proximally immobilized ions. Nature. 517: 347-50. PMID 25592540 DOI: 10.1038/nature14018  1
2015 Cheloha RW, Sullivan JA, Wang T, Sand JM, Sidney J, Sette A, Cook ME, Suresh M, Gellman SH. Consequences of periodic α-to-β(3) residue replacement for immunological recognition of peptide epitopes. Acs Chemical Biology. 10: 844-54. PMID 25559929 DOI: 10.1021/cb500888q  1
2015 Nadithe V, Liu R, Killinger BA, Movassaghian S, Kim NH, Moszczynska AB, Masters KS, Gellman SH, Merkel OM. Screening nylon-3 polymers, a new class of cationic amphiphiles, for siRNA delivery. Molecular Pharmaceutics. 12: 362-74. PMID 25437915 DOI: 10.1021/mp5004724  1
2014 Maynard SJ, Almeida AM, Yoshimi Y, Gellman SH. New charge-bearing amino acid residues that promote β-sheet secondary structure. Journal of the American Chemical Society. 136: 16683-8. PMID 25393077 DOI: 10.1021/ja510265e  1
2014 Giuliano MW, Maynard SJ, Almeida AM, Guo L, Guzei IA, Spencer LC, Gellman SH. A γ-amino acid that favors 12/10-helical secondary structure in α/γ-peptides. Journal of the American Chemical Society. 136: 15046-53. PMID 25301259 DOI: 10.1021/ja5076585  1
2014 Liu R, Suárez JM, Weisblum B, Gellman SH, McBride SM. Synthetic polymers active against Clostridium difficile vegetative cell growth and spore outgrowth. Journal of the American Chemical Society. 136: 14498-504. PMID 25279431 DOI: 10.1021/ja506798e  1
2014 Chakraborty S, Liu R, Hayouka Z, Chen X, Ehrhardt J, Lu Q, Burke E, Yang Y, Weisblum B, Wong GC, Masters KS, Gellman SH. Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits. Journal of the American Chemical Society. 136: 14530-5. PMID 25269798 DOI: 10.1021/ja507576a  1
2014 Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, Keller MP, Attie AD, Saghatelian A, Bisello A, Gellman SH. A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo. Journal of the American Chemical Society. 136: 12848-51. PMID 25191938 DOI: 10.1021/ja507168t  1
2014 Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC. Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli. Plos One. 9: e104500. PMID 25153714 DOI: 10.1371/journal.pone.0104500  1
2014 Cheloha RW, Maeda A, Dean T, Gardella TJ, Gellman SH. Backbone modification of a polypeptide drug alters duration of action in vivo. Nature Biotechnology. 32: 653-5. PMID 24929976 DOI: 10.1038/nbt.2920  1
2014 Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Hydrophobicity and helicity regulate the antifungal activity of 14-helical β-peptides. Acs Chemical Biology. 9: 1613-21. PMID 24837702 DOI: 10.1021/cb500203e  1
2014 Mayer C, Müller MM, Gellman SH, Hilvert D. Building proficient enzymes with foldamer prostheses. Angewandte Chemie (International Ed. in English). 53: 6978-81. PMID 24828837 DOI: 10.1002/anie.201400945  1
2014 Lee MW, Chakraborty S, Schmidt NW, Murgai R, Gellman SH, Wong GC. Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides. Biochimica Et Biophysica Acta. 1838: 2269-79. PMID 24743021 DOI: 10.1016/j.bbamem.2014.04.007  1
2014 Gord JR, Walsh PS, Fisher BF, Gellman SH, Zwier TS. Mimicking the first turn of an α-helix with an unnatural backbone: conformation-specific IR and UV spectroscopy of cyclically constrained β/γ-peptides. The Journal of Physical Chemistry. B. 118: 8246-56. PMID 24694352 DOI: 10.1021/jp5015884  1
2014 Liu R, Chen X, Falk SP, Mowery BP, Karlsson AJ, Weisblum B, Palecek SP, Masters KS, Gellman SH. Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans. Journal of the American Chemical Society. 136: 4333-42. PMID 24606327 DOI: 10.1021/ja500036r  1
2014 Liu R, Chen X, Chakraborty S, Lemke JJ, Hayouka Z, Chow C, Welch RA, Weisblum B, Masters KS, Gellman SH. Tuning the biological activity profile of antibacterial polymers via subunit substitution pattern. Journal of the American Chemical Society. 136: 4410-8. PMID 24601599 DOI: 10.1021/ja500367u  1
2014 Laaser JE, Skoff DR, Ho JJ, Joo Y, Serrano AL, Steinkruger JD, Gopalan P, Gellman SH, Zanni MT. Two-dimensional sum-frequency generation reveals structure and dynamics of a surface-bound peptide. Journal of the American Chemical Society. 136: 956-62. PMID 24372101 DOI: 10.1021/ja408682s  1
2014 Chae PS, Sadaf A, Gellman SH. Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion. Chemistry, An Asian Journal. 9: 110-6. PMID 24347070 DOI: 10.1002/asia.201301097  1
2014 Cho KH, Bae HE, Das M, Gellman SH, Chae PS. Improved glucose-neopentyl glycol (GNG) amphiphiles for membrane protein solubilization and stabilization. Chemistry, An Asian Journal. 9: 632-8. PMID 24288216 DOI: 10.1002/asia.201301303  1
2014 Chae PS, Cho KH, Wander MJ, Bae HE, Gellman SH, Laible PD. Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation. Biochimica Et Biophysica Acta. 1838: 278-86. PMID 24064323 DOI: 10.1016/j.bbamem.2013.09.011  1
2014 Choi H, Chakraborty S, Liu R, Gellman SH, Weisshaar JC. Correction: Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. Coli Plos One. 9. DOI: 10.1371/journal.pone.0116241  1
2014 Stephenson NA, Gellman SH, Stahl SS. Ammonolysis of anilides promoted by ethylene glycol and phosphoric acid Rsc Advances. 4: 46840-46843. DOI: 10.1039/c4ra09065a  1
2013 Chakraborty S, Liu R, Lemke JJ, Hayouka Z, Welch RA, Weisblum B, Masters KS, Gellman SH. Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers. Acs Macro Letters. 2. PMID 24349873 DOI: 10.1021/mz400239r  1
2013 Mortenson DE, Kreitler DF, Yun HG, Gellman SH, Forest KT. Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallographica. Section D, Biological Crystallography. 69: 2506-12. PMID 24311591 DOI: 10.1107/S090744491302444X  1
2013 Giuliano MW, Maynard SJ, Almeida AM, Reidenbach AG, Guo L, Ulrich EC, Guzei IA, Gellman SH. Evaluation of a cyclopentane-based γ-amino acid for the ability to promote α/γ-peptide secondary structure. The Journal of Organic Chemistry. 78: 12351-61. PMID 24303945 DOI: 10.1021/jo401501g  1
2013 Liu R, Chen X, Gellman SH, Masters KS. Nylon-3 polymers that enable selective culture of endothelial cells. Journal of the American Chemical Society. 135: 16296-9. PMID 24156536 DOI: 10.1021/ja408634a  1
2013 Walsh PS, Kusaka R, Buchanan EG, James WH, Fisher BF, Gellman SH, Zwier TS. Cyclic constraints on conformational flexibility in γ-peptides: conformation specific IR and UV spectroscopy. The Journal of Physical Chemistry. A. 117: 12350-62. PMID 24147873 DOI: 10.1021/jp408736t  1
2013 Chae PS, Kruse AC, Gotfryd K, Rana RR, Cho KH, Rasmussen SG, Bae HE, Chandra R, Gether U, Guan L, Kobilka BK, Loland CJ, Byrne B, Gellman SH. Novel tripod amphiphiles for membrane protein analysis. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 15645-51. PMID 24123610 DOI: 10.1002/chem.201301423  1
2013 Hayouka Z, Mortenson DE, Kreitler DF, Weisblum B, Forest KT, Gellman SH. Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue. Journal of the American Chemical Society. 135: 15738-41. PMID 24102563 DOI: 10.1021/ja409082w  1
2013 Kusaka R, Zhang D, Walsh PS, Gord JR, Fisher BF, Gellman SH, Zwier TS. Role of ring-constrained γ-amino acid residues in α/γ-peptide folding: single-conformation UV and IR spectroscopy. The Journal of Physical Chemistry. A. 117: 10847-62. PMID 24070234 DOI: 10.1021/jp408258w  1
2013 Smith BJ, Lee EF, Checco JW, Evangelista M, Gellman SH, Fairlie WD. Structure-guided rational design of α/β-peptide foldamers with high affinity for BCL-2 family prosurvival proteins. Chembiochem : a European Journal of Chemical Biology. 14: 1564-72. PMID 23929624 DOI: 10.1002/cbic.201300351  1
2013 Hayouka Z, Chakraborty S, Liu R, Boersma MD, Weisblum B, Gellman SH. Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures. Journal of the American Chemical Society. 135: 11748-51. PMID 23909610 DOI: 10.1021/ja406231b  1
2013 Shin YH, Mortenson DE, Satyshur KA, Forest KT, Gellman SH. Differential impact of β and γ residue preorganization on α/β/γ-peptide helix stability in water. Journal of the American Chemical Society. 135: 8149-52. PMID 23701135 DOI: 10.1021/ja403319q  1
2013 Liu R, Chen X, Hayouka Z, Chakraborty S, Falk SP, Weisblum B, Masters KS, Gellman SH. Nylon-3 polymers with selective antifungal activity. Journal of the American Chemical Society. 135: 5270-3. PMID 23547967 DOI: 10.1021/ja4006404  1
2013 Johnson LM, Gellman SH. α-Helix mimicry with α/β-peptides. Methods in Enzymology. 523: 407-29. PMID 23422441 DOI: 10.1016/B978-0-12-394292-0.00019-9  1
2013 Chae PS, Wander MJ, Cho KH, Laible PD, Gellman SH. Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization. Molecular Biosystems. 9: 626-9. PMID 23377371 DOI: 10.1039/c3mb25584k  1
2013 Arnold U, Huck BR, Gellman SH, Raines RT. Protein prosthesis: β-peptides as reverse-turn surrogates. Protein Science : a Publication of the Protein Society. 22: 274-9. PMID 23238807 DOI: 10.1002/pro.2208  1
2013 Chae PS, Rana RR, Gotfryd K, Rasmussen SG, Kruse AC, Cho KH, Capaldi S, Carlsson E, Kobilka B, Loland CJ, Gether U, Banerjee S, Byrne B, Lee JK, Gellman SH. Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study. Chemical Communications (Cambridge, England). 49: 2287-9. PMID 23165475 DOI: 10.1039/c2cc36844g  1
2013 Choi SH, Ivancic M, Guzei IA, Gellman SH. Structural characterization of peptide oligomers containing (1R,2S)-2-aminocyclohexanecarboxylic acid (cis-ACHC) European Journal of Organic Chemistry. 3464-3469. DOI: 10.1002/ejoc.201300118  1
2013 Chae PS, Wander MJ, Bowling AP, Laible PD, Gellman SH. Corrigenda to Glycotripod Amphiphiles for Solubilization and Stabilization of a Membrane-Protein Superassembly: Importance of Branching in the Hydrophilic Portion [ChemBioChem, 9, (2008) 1706-1709] DOI 10.1002/cbic.200800169 Chembiochem. 14: 665. DOI: 10.1002/cbic.201300113  1
2012 Zhang J, Markiewicz MJ, Weisblum B, Stahl SS, Gellman SH. Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams. Acs Macro Letters. 1: 714-717. PMID 23355958 DOI: 10.1021/mz300172y  1
2012 Woys AM, Almeida AM, Wang L, Chiu CC, McGovern M, de Pablo JJ, Skinner JL, Gellman SH, Zanni MT. Parallel β-sheet vibrational couplings revealed by 2D IR spectroscopy of an isotopically labeled macrocycle: quantitative benchmark for the interpretation of amyloid and protein infrared spectra. Journal of the American Chemical Society. 134: 19118-28. PMID 23113791 DOI: 10.1021/ja3074962  1
2012 Steinkruger JD, Bartlett GJ, Woolfson DN, Gellman SH. Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils. Journal of the American Chemical Society. 134: 15652-5. PMID 22974448 DOI: 10.1021/ja3063088  1
2012 Buchanan EG, James WH, Choi SH, Guo L, Gellman SH, Müller CW, Zwier TS. Single-conformation infrared spectra of model peptides in the amide I and amide II regions: experiment-based determination of local mode frequencies and inter-mode coupling. The Journal of Chemical Physics. 137: 094301. PMID 22957563 DOI: 10.1063/1.4747507  1
2012 Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH. A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 9485-90. PMID 22730191 DOI: 10.1002/chem.201200069  1
2012 Liu R, Vang KZ, Kreeger PK, Gellman SH, Masters KS. Experimental and computational analysis of cellular interactions with nylon-3-bearing substrates. Journal of Biomedical Materials Research. Part A. 100: 2750-9. PMID 22623026 DOI: 10.1002/jbm.a.34211  1
2012 Guo L, Zhang W, Guzei IA, Spencer LC, Gellman SH. New preorganized γ-amino acids as foldamer building blocks. Organic Letters. 14: 2582-5. PMID 22568480 DOI: 10.1021/ol3008815  1
2012 Haase HS, Peterson-Kaufman KJ, Lan Levengood SK, Checco JW, Murphy WL, Gellman SH. Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling. Journal of the American Chemical Society. 134: 7652-5. PMID 22548447 DOI: 10.1021/ja302469a  1
2012 Johnson LM, Mortenson DE, Yun HG, Horne WS, Ketas TJ, Lu M, Moore JP, Gellman SH. Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array. Journal of the American Chemical Society. 134: 7317-20. PMID 22524614 DOI: 10.1021/ja302428d  1
2012 Liu R, Masters KS, Gellman SH. Polymer chain length effects on fibroblast attachment on nylon-3-modified surfaces. Biomacromolecules. 13: 1100-5. PMID 22455338 DOI: 10.1021/bm201847n  1
2012 Steinkruger JD, Bartlett GJ, Hadley EB, Fay L, Woolfson DN, Gellman SH. The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif. Journal of the American Chemical Society. 134: 2626-33. PMID 22296518 DOI: 10.1021/ja208855x  1
2012 Mortenson DE, Satyshur KA, Guzei IA, Forest KT, Gellman SH. Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations. Journal of the American Chemical Society. 134: 2473-6. PMID 22280019 DOI: 10.1021/ja210045s  1
2012 Zhang J, Markiewicz MJ, Mowery BP, Weisblum B, Stahl SS, Gellman SH. C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities. Biomacromolecules. 13: 323-31. PMID 22168316 DOI: 10.1021/bm2013058  1
2012 Almeida AM, Li R, Gellman SH. Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking. Journal of the American Chemical Society. 134: 75-8. PMID 22148521 DOI: 10.1021/ja208856c  1
2012 Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, Smith BJ, Horne WS, Fairlie WD, Gellman SH. Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain. Journal of the American Chemical Society. 134: 315-23. PMID 22040025 DOI: 10.1021/ja207148m  1
2012 Guo L, Zhang W, Guzei IA, Spencer LC, Gellman SH. Helical secondary structures in 2:1 and 1:2 α/γ-peptide foldamers Tetrahedron. 68: 4413-4417. DOI: 10.1016/j.tet.2012.01.079  1
2011 Buchanan EG, James WH, Gutberlet A, Dean JC, Guo L, Gellman SH, Zwier TS. Single-conformation spectroscopy and population analysis of model γ-peptides: new tests of amide stacking. Faraday Discussions. 150: 209-26; discussion 2. PMID 22457950 DOI: 10.1039/c1fd00001b  1
2011 Segman-Magidovich S, Lee MR, Vaiser V, Struth B, Gellman SH, Rapaport H. Sheet-like assemblies of charged amphiphilic α/β-peptides at the air-water interface. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 14857-66. PMID 22105992 DOI: 10.1002/chem.201101775  1
2011 James WH, Buchanan EG, Müller CW, Dean JC, Kosenkov D, Slipchenko LV, Guo L, Reidenbach AG, Gellman SH, Zwier TS. Evolution of amide stacking in larger γ-peptides: triamide H-bonded cycles. The Journal of Physical Chemistry. A. 115: 13783-98. PMID 21978283 DOI: 10.1021/jp205527e  1
2011 James WH, Buchanan EG, Guo L, Gellman SH, Zwier TS. Competition between amide stacking and intramolecular H bonds in γ-peptide derivatives: controlling nearest-neighbor preferences. The Journal of Physical Chemistry. A. 115: 11960-70. PMID 21928850 DOI: 10.1021/jp2081319  1
2011 Freire F, Gellman SH. Macrocyclic Design Strategies for Small, Stable Parallel β-Sheet Scaffolds. Journal of the American Chemical Society. 133: 12318. PMID 21927061 DOI: 10.1021/ja2055148  0.84
2011 Pomerantz WC, Yuwono VM, Drake R, Hartgerink JD, Abbott NL, Gellman SH. Lyotropic liquid crystals formed from ACHC-rich β-peptides. Journal of the American Chemical Society. 133: 13604-13. PMID 21815636 DOI: 10.1021/ja204874h  1
2011 Freire F, Almeida AM, Fisk JD, Steinkruger JD, Gellman SH. Impact of strand length on the stability of parallel-β-sheet secondary structure. Angewandte Chemie (International Ed. in English). 50: 8735-8. PMID 21812082 DOI: 10.1002/anie.201102986  1
2011 Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, et al. Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature. 477: 549-55. PMID 21772288 DOI: 10.1038/nature10361  1
2011 Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD. Structural basis of Bcl-xL recognition by a BH3-mimetic α/β-peptide generated by sequence-based design. Chembiochem : a European Journal of Chemical Biology. 12: 2025-32. PMID 21744457 DOI: 10.1002/cbic.201100314  1
2011 Johnson LM, Horne WS, Gellman SH. Broad distribution of energetically important contacts across an extended protein interface. Journal of the American Chemical Society. 133: 10038-41. PMID 21644542 DOI: 10.1021/ja203358t  1
2011 Guo L, Zhang W, Reidenbach AG, Giuliano MW, Guzei IA, Spencer LC, Gellman SH. Characteristic structural parameters for the γ-peptide 14-helix: importance of subunit preorganization. Angewandte Chemie (International Ed. in English). 50: 5843-6. PMID 21567680 DOI: 10.1002/anie.201101301  1
2011 Sawada T, Gellman SH. Structural mimicry of the α-helix in aqueous solution with an isoatomic α/β/γ-peptide backbone. Journal of the American Chemical Society. 133: 7336-9. PMID 21520956 DOI: 10.1021/ja202175a  1
2011 Selao TT, Branca R, Chae PS, Lehtiö J, Gellman SH, Rasmussen SG, Nordlund S, Norén A. Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum. Journal of Proteome Research. 10: 2703-14. PMID 21443180 DOI: 10.1021/pr100838x  1
2011 Acevedo-Vélez C, Andre G, Dufrêne YF, Gellman SH, Abbott NL. Single-molecule force spectroscopy of β-peptides that display well-defined three-dimensional chemical patterns. Journal of the American Chemical Society. 133: 3981-8. PMID 21361359 DOI: 10.1021/ja1089183  1
2011 Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, et al. Structure and function of an irreversible agonist-β(2) adrenoceptor complex. Nature. 469: 236-40. PMID 21228876 DOI: 10.1038/nature09665  1
2011 Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, et al. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 469: 175-80. PMID 21228869 DOI: 10.1038/nature09648  1
2011 Thiele CM, Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystalline phases from helical β-peptides as alignment media. Chemical Communications (Cambridge, England). 47: 502-4. PMID 20972503 DOI: 10.1039/c0cc02123g  1
2010 Chae PS, Laible PD, Gellman SH. Tripod Amphiphiles for Membrane Protein Manipulation. Molecular Biosystems. 6: 89-94. PMID 23814603 DOI: 10.1039/b915162c  1
2010 Chae PS, Gotfryd K, Pacyna J, Miercke LJ, Rasmussen SG, Robbins RA, Rana RR, Loland CJ, Kobilka B, Stroud R, Byrne B, Gether U, Gellman SH. Tandem facial amphiphiles for membrane protein stabilization. Journal of the American Chemical Society. 132: 16750-2. PMID 21049926 DOI: 10.1021/ja1072959  1
2010 Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, ... ... Gellman SH, et al. Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nature Methods. 7: 1003-8. PMID 21037590 DOI: 10.1038/nmeth.1526  1
2010 Karlsson AJ, Flessner RM, Gellman SH, Lynn DM, Palecek SP. Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans. Biomacromolecules. 11: 2321-8. PMID 20831274 DOI: 10.1021/bm100424s  1
2010 Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups. Journal of the American Chemical Society. 132: 13879-85. PMID 20828159 DOI: 10.1021/ja1062532  1
2010 Price JL, Horne WS, Gellman SH. Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles. Journal of the American Chemical Society. 132: 12378-87. PMID 20718422 DOI: 10.1021/ja103543s  1
2010 Guo L, Almeida AM, Zhang W, Reidenbach AG, Choi SH, Guzei IA, Gellman SH. Helix formation in preorganized beta/gamma-peptide foldamers: hydrogen-bond analogy to the alpha-helix without alpha-amino acid residues. Journal of the American Chemical Society. 132: 7868-9. PMID 20491510 DOI: 10.1021/ja103233a  1
2010 Dohm MT, Mowery BP, Czyzewski AM, Stahl SS, Gellman SH, Barron AE. Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers. Journal of the American Chemical Society. 132: 7957-67. PMID 20481635 DOI: 10.1021/ja909734n  1
2010 Steinkruger JD, Woolfson DN, Gellman SH. Side-chain pairing preferences in the parallel coiled-coil dimer motif: insight on ion pairing between core and flanking sites. Journal of the American Chemical Society. 132: 7586-8. PMID 20465308 DOI: 10.1021/ja100080q  1
2010 Chae PS, Guzei IA, Gellman SH. Crystallographic characterization of N-oxide tripod amphiphiles. Journal of the American Chemical Society. 132: 1953-9. PMID 20095541 DOI: 10.1021/ja9085148  1
2010 James WH, Baquero EE, Choi SH, Gellman SH, Zwier TS. Laser spectroscopy of conformationally constrained alpha/beta-peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe. The Journal of Physical Chemistry. A. 114: 1581-91. PMID 20039717 DOI: 10.1021/jp9090975  1
2010 Segman S, Lee MR, Vaiser V, Gellman SH, Rapaport H. Highly stable pleated-sheet secondary structure in assemblies of amphiphilic alpha/beta-peptides at the air-water interface. Angewandte Chemie (International Ed. in English). 49: 716-9. PMID 20025003 DOI: 10.1002/anie.200904566  1
2010 Price JL, Hadley EB, Steinkruger JD, Gellman SH. Detection and analysis of chimeric tertiary structures by backbone thioester exchange: packing of an alpha helix against an alpha/beta-peptide helix. Angewandte Chemie (International Ed. in English). 49: 368-71. PMID 19967682 DOI: 10.1002/anie.200904714  1
2010 Zhang J, Gellman SH, Stahl SS. Kinetics of anionic ring-opening polymerization of variously substituted β-lactams: Homopolymerization and copolymerization Macromolecules. 43: 5618-5626. DOI: 10.1021/ma1010809  1
2009 Guo L, Chi Y, Almeida AM, Guzei IA, Parker BK, Gellman SH. Stereospecific synthesis of conformationally constrained gamma-amino acids: new foldamer building blocks that support helical secondary structure. Journal of the American Chemical Society. 131: 16018-20. PMID 19886693 DOI: 10.1021/ja907233q  1
2009 Lee MR, Stahl SS, Gellman SH, Masters KS. Nylon-3 copolymers that generate cell-adhesive surfaces identified by library screening. Journal of the American Chemical Society. 131: 16779-89. PMID 19886604 DOI: 10.1021/ja9050636  1
2009 James WH, Müller CW, Buchanan EG, Nix MG, Guo L, Roskop L, Gordon MS, Slipchenko LV, Gellman SH, Zwier TS. Intramolecular amide stacking and its competition with hydrogen bonding in a small foldamer. Journal of the American Chemical Society. 131: 14243-5. PMID 19757786 DOI: 10.1021/ja9054965  1
2009 Horne WS, Johnson LM, Ketas TJ, Klasse PJ, Lu M, Moore JP, Gellman SH. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers. Proceedings of the National Academy of Sciences of the United States of America. 106: 14751-6. PMID 19706443 DOI: 10.1073/pnas.0902663106  0.6
2009 Pomerantz WC, Hadley EB, Fry CG, Gellman SH. In situ monitoring of backbone thioester exchange by 19F NMR. Chembiochem : a European Journal of Chemical Biology. 10: 2177-81. PMID 19644993 DOI: 10.1002/cbic.200900380  1
2009 Stephenson NA, Zhu J, Gellman SH, Stahl SS. Catalytic transamidation reactions compatible with tertiary amide metathesis under ambient conditions. Journal of the American Chemical Society. 131: 10003-8. PMID 19621957 DOI: 10.1021/ja8094262  1
2009 Mowery BP, Lindner AH, Weisblum B, Stahl SS, Gellman SH. Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides. Journal of the American Chemical Society. 131: 9735-45. PMID 19601684 DOI: 10.1021/ja901613g  1
2009 Giuliano MW, Horne WS, Gellman SH. An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure. Journal of the American Chemical Society. 131: 9860-1. PMID 19580264 DOI: 10.1021/ja8099294  1
2009 Lu D, Windsor MA, Gellman SH, Keck JL. Peptide inhibitors identify roles for SSB C-terminal residues in SSB/exonuclease I complex formation. Biochemistry. 48: 6764-71. PMID 19527069 DOI: 10.1021/bi900361r  1
2009 Karlsson AJ, Pomerantz WC, Neilsen KJ, Gellman SH, Palecek SP. Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms. Acs Chemical Biology. 4: 567-79. PMID 19518070 DOI: 10.1021/cb900093r  1
2009 Miller CA, Gellman SH, Abbott NL, de Pablo JJ. Association of helical beta-peptides and their aggregation behavior from the potential of mean force in explicit solvent. Biophysical Journal. 96: 4349-62. PMID 19486660 DOI: 10.1016/j.bpj.2008.11.076  1
2009 Freire F, Gellman SH. Macrocyclic design strategies for small, stable parallel beta-sheet scaffolds. Journal of the American Chemical Society. 131: 7970-2. PMID 19456161 DOI: 10.1021/ja902210f  1
2009 James WH, Baquero EE, Shubert VA, Choi SH, Gellman SH, Zwier TS. Single-conformation and diastereomer specific ultraviolet and infrared spectroscopy of model synthetic foldamers: alpha/beta-peptides. Journal of the American Chemical Society. 131: 6574-90. PMID 19366210 DOI: 10.1021/ja901051v  1
2009 Lee EF, Sadowsky JD, Smith BJ, Czabotar PE, Peterson-Kaufman KJ, Colman PM, Gellman SH, Fairlie WD. High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL. Angewandte Chemie (International Ed. in English). 48: 4318-22. PMID 19229915 DOI: 10.1002/anie.200805761  1
2009 Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of helical secondary structures in 2:1 and 1:2 alpha/beta-peptides. Journal of the American Chemical Society. 131: 2917-24. PMID 19203269 DOI: 10.1021/ja808168y  1
2009 Zhang J, Kissounko DA, Lee SE, Gellman SH, Stahl SS. Access to poly-beta-peptides with functionalized side chains and end groups via controlled ring-opening polymerization of beta-lactams. Journal of the American Chemical Society. 131: 1589-97. PMID 19125651 DOI: 10.1021/ja8069192  1
2009 Müller MM, Windsor MA, Pomerantz WC, Gellman SH, Hilvert D. A rationally designed aldolase foldamer. Angewandte Chemie (International Ed. in English). 48: 922-5. PMID 19090515 DOI: 10.1002/anie.200804996  1
2008 Pizzey CL, Pomerantz WC, Sung BJ, Yuwono VM, Gellman SH, Hartgerink JD, Yethiraj A, Abbott NL. Characterization of nanofibers formed by self-assembly of beta-peptide oligomers using small angle x-ray scattering. The Journal of Chemical Physics. 129: 095103. PMID 19044891 DOI: 10.1063/1.2955745  1
2008 Lee MR, Stahl SS, Gellman SH. Synthesis of beta-lactams bearing functionalized side chains from a readily available precursor. Organic Letters. 10: 5317-9. PMID 18956871 DOI: 10.1021/ol802274x  1
2008 Vaz E, Pomerantz WC, Geyer M, Gellman SH, Brunsveld L. Comparison of design strategies for promotion of beta-peptide 14-helix stability in water. Chembiochem : a European Journal of Chemical Biology. 9: 2254-9. PMID 18756554 DOI: 10.1002/cbic.200800355  1
2008 Miller CA, Hernández-Ortiz JP, Abbott NL, Gellman SH, de Pablo JJ. Dipole-induced self-assembly of helical beta-peptides. The Journal of Chemical Physics. 129: 015102. PMID 18624501 DOI: 10.1063/1.2928700  1
2008 Miller CA, Gellman SH, Abbott NL, de Pablo JJ. Mechanical stability of helical beta-peptides and a comparison of explicit and implicit solvent models. Biophysical Journal. 95: 3123-36. PMID 18621835 DOI: 10.1529/biophysj.108.134833  1
2008 Horne WS, Gellman SH. Foldamers with heterogeneous backbones. Accounts of Chemical Research. 41: 1399-408. PMID 18590282 DOI: 10.1021/ar800009n  1
2008 Horne WS, Price JL, Gellman SH. Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proceedings of the National Academy of Sciences of the United States of America. 105: 9151-6. PMID 18587049 DOI: 10.1073/pnas.0801135105  1
2008 Chae PS, Wander MJ, Bowling AP, Laible PD, Gellman SH. Glycotripod amphiphiles for solubilization and stabilization of a membrane-protein superassembly: importance of branching in the hydrophilic portion. Chembiochem : a European Journal of Chemical Biology. 9: 1706-9. PMID 18576450 DOI: 10.1002/cbic.200800169  1
2008 Freire F, Fisk JD, Peoples AJ, Ivancic M, Guzei IA, Gellman SH. Diacid linkers that promote parallel beta-sheet secondary structure in water. Journal of the American Chemical Society. 130: 7839-41. PMID 18507461 DOI: 10.1021/ja802042c  1
2008 Boersma MD, Sadowsky JD, Tomita YA, Gellman SH. Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain. Protein Science : a Publication of the Protein Society. 17: 1232-40. PMID 18467496 DOI: 10.1110/ps.032896.107  1
2008 Epand RF, Mowery BP, Lee SE, Stahl SS, Lehrer RI, Gellman SH, Epand RM. Dual mechanism of bacterial lethality for a cationic sequence-random copolymer that mimics host-defense antimicrobial peptides. Journal of Molecular Biology. 379: 38-50. PMID 18440552 DOI: 10.1016/j.jmb.2008.03.047  1
2008 Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1:1 residue alternation. Journal of the American Chemical Society. 130: 6544-50. PMID 18439014 DOI: 10.1021/ja800355p  1
2008 Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, Bresnick EH, Sheibani N, Gellman SH. A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor Analytical Biochemistry. 378: 8-14. PMID 18413228 DOI: 10.1016/j.ab.2008.03.043  1
2008 Zhu X, Koenig P, Gellman SH, Yethiraj A, Cui Q. Establishing effective simulation protocols for beta- and alpha/beta-peptides. II. Molecular mechanical (MM) model for a cyclic beta-residue. The Journal of Physical Chemistry. B. 112: 5439-48. PMID 18402479 DOI: 10.1021/jp077601y  1
2008 Pomerantz WC, Grygiel TL, Lai JR, Gellman SH. Distinctive circular dichroism signature for 14-helix-bundle formation by beta-peptides. Organic Letters. 10: 1799-802. PMID 18396884 DOI: 10.1021/ol800622e  1
2008 Akkarawongsa R, Potocky TB, English EP, Gellman SH, Brandt CR. Inhibition of herpes simplex virus type 1 infection by cationic beta-peptides. Antimicrobial Agents and Chemotherapy. 52: 2120-9. PMID 18391029 DOI: 10.1128/AAC.01424-07  1
2008 Chi Y, Guo L, Kopf NA, Gellman SH. Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to gamma2-amino acids. Journal of the American Chemical Society. 130: 5608-9. PMID 18386925 DOI: 10.1021/ja800345r  1
2008 Baquero EE, James WH, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-beta3-hAla-NHMe and Ac-beta3-hAla-beta3-hPhe-NHMe. Journal of the American Chemical Society. 130: 4795-807. PMID 18345673 DOI: 10.1021/ja078272q  1
2008 Baquero EE, James WH, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-NHMe and Ac-beta3-hTyr-NHMe. Journal of the American Chemical Society. 130: 4784-94. PMID 18345672 DOI: 10.1021/ja078271y  1
2008 Horne WS, Boersma MD, Windsor MA, Gellman SH. Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. Angewandte Chemie (International Ed. in English). 47: 2853-6. PMID 18330876 DOI: 10.1002/anie.200705315  1
2008 Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH. Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. Journal of Combinatorial Chemistry. 10: 204-15. PMID 18275161 DOI: 10.1021/cc700153z  1
2008 Hadley EB, Testa OD, Woolfson DN, Gellman SH. Preferred side-chain constellations at antiparallel coiled-coil interfaces. Proceedings of the National Academy of Sciences of the United States of America. 105: 530-5. PMID 18184807 DOI: 10.1073/pnas.0709068105  1
2008 Pomerantz WC, Yuwono VM, Pizzey CL, Hartgerink JD, Abbott NL, Gellman SH. Nanofibers and lyotropic liquid crystals from a class of self-assembling beta-peptides. Angewandte Chemie (International Ed. in English). 47: 1241-4. PMID 18183558 DOI: 10.1002/anie.200704372  1
2008 Hoerter JM, Otte KM, Gellman SH, Cui Q, Stahl SS. Discovery and mechanistic study of Al(III)-catalyzed transamidation of tertiary amides. Journal of the American Chemical Society. 130: 647-54. PMID 18092780 DOI: 10.1021/ja0762994  1
2008 Horne WS, Price JL, Gellman SH. Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, (9151-9156) DOI: 10.1073/pnas.0801135105) Proceedings of the National Academy of Sciences of the United States of America. 105: 17205. DOI: 10.1073/pnas.0808591105  1
2007 Mowery BP, Lee SE, Kissounko DA, Epand RF, Epand RM, Weisblum B, Stahl SS, Gellman SH. Mimicry of antimicrobial host-defense peptides by random copolymers. Journal of the American Chemical Society. 129: 15474-6. PMID 18034491 DOI: 10.1021/ja077288d  1
2007 Choi SH, Guzei IA, Gellman SH. Crystallographic characterization of the alpha/beta-peptide 14/15-helix. Journal of the American Chemical Society. 129: 13780-1. PMID 17949002 DOI: 10.1021/ja0753344  1
2007 Cornilescu G, Hadley EB, Woll MG, Markley JL, Gellman SH, Cornilescu CC. Solution structure of a small protein containing a fluorinated side chain in the core. Protein Science : a Publication of the Protein Society. 16: 2089. PMID 17915350 DOI: 10.1110/ps.062557707  1
2007 Hadley EB, Witek AM, Freire F, Peoples AJ, Gellman SH. Thermodynamic analysis of beta-sheet secondary structure by backbone thioester exchange. Angewandte Chemie (International Ed. in English). 46: 7056-9. PMID 17691093 DOI: 10.1002/anie.200702449  1
2007 Tang L, Hopper ED, Tong Y, Sadowsky JD, Peterson KJ, Gellman SH, Fitzgerald MC. H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. Analytical Chemistry. 79: 5869-77. PMID 17580981 DOI: 10.1021/ac0700777  1
2007 Potocky TB, Silvius J, Menon AK, Gellman SH. HeLa cell entry by guanidinium-rich beta-peptides: importance of specific cation-cell surface interactions. Chembiochem : a European Journal of Chemical Biology. 8: 917-26. PMID 17503427 DOI: 10.1002/cbic.200600563  1
2007 Sadowsky JD, Murray JK, Tomita Y, Gellman SH. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL. Chembiochem : a European Journal of Chemical Biology. 8: 903-16. PMID 17503422 DOI: 10.1002/cbic.200600546  1
2007 Price JL, Horne WS, Gellman SH. Discrete heterogeneous quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. Journal of the American Chemical Society. 129: 6376-7. PMID 17465552 DOI: 10.1021/ja071203r  1
2007 Chi Y, English EP, Pomerantz WC, Horne WS, Joyce LA, Alexander LR, Fleming WS, Hopkins EA, Gellman SH. Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. Journal of the American Chemical Society. 129: 6050-5. PMID 17439122 DOI: 10.1021/ja070063i  1
2007 Murray JK, Gellman SH. Targeting protein-protein interactions: lessons from p53/MDM2. Biopolymers. 88: 657-86. PMID 17427181 DOI: 10.1002/bip.20741  1
2007 Murray JK, Gellman SH. Parallel synthesis of peptide libraries using microwave irradiation. Nature Protocols. 2: 624-31. PMID 17406623 DOI: 10.1038/nprot.2007.23  1
2007 Lee MR, Raguse TL, Schinnerl M, Pomerantz WC, Wang X, Wipf P, Gellman SH. Origins of the high 14-helix propensity of cyclohexyl-rigidified residues in beta-peptides. Organic Letters. 9: 1801-4. PMID 17394351 DOI: 10.1021/ol070511r  1
2007 Horne WS, Price JL, Keck JL, Gellman SH. Helix bundle quaternary structure from alpha/beta-peptide foldamers. Journal of the American Chemical Society. 129: 4178-80. PMID 17362016 DOI: 10.1021/ja070396f  1
2007 Kissounko DA, Hoerter JM, Guzei IA, Cui Q, Gellman SH, Stahl SS. TiIV-mediated reactions between primary amines and secondary carboxamides: amidine formation versus transamidation. Journal of the American Chemical Society. 129: 1776-83. PMID 17284008 DOI: 10.1021/ja0650293  1
2007 Schmitt MA, Weisblum B, Gellman SH. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. Journal of the American Chemical Society. 129: 417-28. PMID 17212422 DOI: 10.1021/ja0666553  1
2007 Sadowsky JD, Fairlie WD, Hadley EB, Lee HS, Umezawa N, Nikolovska-Coleska Z, Wang S, Huang DC, Tomita Y, Gellman SH. (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions. Journal of the American Chemical Society. 129: 139-54. PMID 17199293 DOI: 10.1021/ja0662523  1
2007 Bell CM, Kissounko DA, Gellman SH, Stahl SS. Catalytic metathesis of simple secondary amides. Angewandte Chemie (International Ed. in English). 46: 761-3. PMID 17163571 DOI: 10.1002/anie.200603588  1
2007 Cornilescu G, Hadley EB, Woll MG, Markley JL, Gellman SH, Cornilescu CC. Solution structure of a small protein containing a fluorinated side chain in the core. Protein Science : a Publication of the Protein Society. 16: 14-9. PMID 17123960 DOI: 10.1110/ps.062557707  1
2007 Pomerantz WC, Cadwell KD, Hsu YJ, Gellman SH, Abbott NL. Sequence dependent behavior of amphiphilic β-peptides on gold surfaces Chemistry of Materials. 19: 4436-4441. DOI: 10.1021/cm070265d  1
2006 Hadley EB, Gellman SH. An antiparallel alpha-helical coiled-coil model system for rapid assessment of side-chain recognition at the hydrophobic interface. Journal of the American Chemical Society. 128: 16444-5. PMID 17177361 DOI: 10.1021/ja067178r  1
2006 Lai JR, Epand RF, Weisblum B, Epand RM, Gellman SH. Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. Biochemistry. 45: 15718-30. PMID 17176094 DOI: 10.1021/bi0617759  1
2006 Woll MG, Hadley EB, Mecozzi S, Gellman SH. Stabilizing and destabilizing effects of phenylalanine --> F5-phenylalanine mutations on the folding of a small protein. Journal of the American Chemical Society. 128: 15932-3. PMID 17165695 DOI: 10.1021/ja0634573  1
2006 Karlsson AJ, Pomerantz WC, Weisblum B, Gellman SH, Palecek SP. Antifungal activity from 14-helical beta-peptides. Journal of the American Chemical Society. 128: 12630-1. PMID 17002340 DOI: 10.1021/ja064630y  1
2006 Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, Boyer ME, Gomez TM, Hasso SM, Fallon JF, Bresnick EH. An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis. The Journal of Cell Biology. 174: 1047-58. PMID 17000881 DOI: 10.1083/jcb.200603152  1
2006 Rathore N, Gellman SH, de Pablo JJ. Thermodynamic stability of beta-peptide helices and the role of cyclic residues. Biophysical Journal. 91: 3425-35. PMID 16905613 DOI: 10.1529/biophysj.106.084491  1
2006 Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystals from designed helical beta-peptides. Journal of the American Chemical Society. 128: 8730-1. PMID 16819857 DOI: 10.1021/ja062412z  1
2006 Fisk JD, Schmitt MA, Gellman SH. Thermodynamic analysis of autonomous parallel beta-sheet formation in water. Journal of the American Chemical Society. 128: 7148-9. PMID 16734453 DOI: 10.1021/ja060942p  1
2006 Chi Y, Gellman SH. Enantioselective organocatalytic aminomethylation of aldehydes: a role for ionic interactions and efficient access to beta2-amino acids. Journal of the American Chemical Society. 128: 6804-5. PMID 16719457 DOI: 10.1021/ja061731n  1
2006 Hoerter JM, Otte KM, Gellman SH, Stahl SS. Mechanism of Al(III)-catalyzed transamidation of unactivated secondary carboxamides. Journal of the American Chemical Society. 128: 5177-83. PMID 16608354 DOI: 10.1021/ja060331x  1
2006 Schmitt MA, Choi SH, Guzei IA, Gellman SH. New helical foldamers: heterogeneous backbones with 1:2 and 2:1 alpha:beta-amino acid residue patterns. Journal of the American Chemical Society. 128: 4538-9. PMID 16594667 DOI: 10.1021/ja060281w  1
2006 Epand RF, Schmitt MA, Gellman SH, Epand RM. Role of membrane lipids in the mechanism of bacterial species selective toxicity by two alpha/beta-antimicrobial peptides. Biochimica Et Biophysica Acta. 1758: 1343-50. PMID 16564494 DOI: 10.1016/j.bbamem.2006.01.018  1
2006 Murray JK, Gellman SH. Microwave-assisted parallel synthesis of a 14-helical beta-peptide library. Journal of Combinatorial Chemistry. 8: 58-65. PMID 16398554 DOI: 10.1021/cc0501099  1
2006 English EP, Chumanov RS, Gellman SH, Compton T. Rational development of beta-peptide inhibitors of human cytomegalovirus entry. The Journal of Biological Chemistry. 281: 2661-7. PMID 16275647 DOI: 10.1074/jbc.M508485200  1
2005 Epand RF, Schmitt MA, Gellman SH, Sen A, Auger M, Hughes DW, Epand RM. Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids. Molecular Membrane Biology. 22: 457-69. PMID 16373318 DOI: 10.1080/09687860500370562  1
2005 Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, Chen J, Gellman SH. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 127: 13271-80. PMID 16173757 DOI: 10.1021/ja052733v  1
2005 Schmitt MA, Choi SH, Guzei IA, Gellman SH. Residue requirements for helical folding in short alpha/beta-peptides: crystallographic characterization of the 11-helix in an optimized sequence. Journal of the American Chemical Society. 127: 13130-1. PMID 16173725 DOI: 10.1021/ja0536163  1
2005 Chi Y, Gellman SH. Diphenylprolinol methyl ether: a highly enantioselective catalyst for Michael addition of aldehydes to simple enones. Organic Letters. 7: 4253-6. PMID 16146400 DOI: 10.1021/ol0517729  1
2005 Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang S, Tomita Y, Gellman SH. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. Journal of the American Chemical Society. 127: 11966-8. PMID 16117535 DOI: 10.1021/ja053678t  1
2005 Peelen TJ, Chi Y, Gellman SH. Enantioselective organocatalytic Michael additions of aldehydes to enones with imidazolidinones: cocatalyst effects and evidence for an enamine intermediate. Journal of the American Chemical Society. 127: 11598-9. PMID 16104725 DOI: 10.1021/ja0532584  1
2005 Porter EA, Weisblum B, Gellman SH. Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity. Journal of the American Chemical Society. 127: 11516-29. PMID 16089482 DOI: 10.1021/ja0519785  1
2005 Chi Y, Peelen TJ, Gellman SH. A rapid 1H NMR assay for enantiomeric excess of alpha-substituted aldehydes. Organic Letters. 7: 3469-72. PMID 16048319 DOI: 10.1021/ol051174u  1
2005 Theisen MJ, Potocky TB, McQuade DT, Gellman SH, Chiu ML. Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile. Biochimica Et Biophysica Acta. 1751: 213-6. PMID 15963773 DOI: 10.1016/j.bbapap.2005.04.011  1
2005 Eldred SE, Pancost MR, Otte KM, Rozema D, Stahl SS, Gellman SH. Effects of side chain configuration and backbone spacing on the gene delivery properties of lysine-derived cationic polymers. Bioconjugate Chemistry. 16: 694-9. PMID 15898739 DOI: 10.1021/bc050017c  1
2005 Huck BR, Gellman SH. Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomers. The Journal of Organic Chemistry. 70: 3353-62. PMID 15844969 DOI: 10.1021/jo048639z  1
2005 Murray JK, Gellman SH. Application of microwave irradiation to the synthesis of 14-helical beta-peptides. Organic Letters. 7: 1517-20. PMID 15816741 DOI: 10.1021/ol0501727  1
2005 Espinosa JF, Syud FA, Gellman SH. An autonomously folding beta-hairpin derived from the human YAP65 WW domain: attempts to define a minimum ligand-binding motif. Biopolymers. 80: 303-11. PMID 15800888 DOI: 10.1002/bip.20205  1
2005 Potocky TB, Menon AK, Gellman SH. Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptides. Journal of the American Chemical Society. 127: 3686-7. PMID 15771489 DOI: 10.1021/ja042566j  1
2005 De Stasio G, Schmitt MA, Gellman SH. Spectromicroscopy at the organic-inorganic interface in biominerals American Journal of Science. 305: 673-686. DOI: 10.2475/ajs.305.6-8.673  1
2005 Kissounko DA, Guzei IA, Gellman SH, Stahl SS. Titanium(IV)-mediated conversion of carboxamides to amidines and implications for catalytic transamidation Organometallics. 24: 5208-5210. DOI: 10.1021/om050768y  1
2005 Gelman MA, Gellman SH. Using Constrained β-Amino Acid Residues to Control β-Peptide Shape and Function Enantioselective Synthesis of β-Amino Acids: Second Edition. 527-591. DOI: 10.1002/0471698482.ch22  1
2004 Peelen TJ, Chi Y, English EP, Gellman SH. Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical beta-peptides. Organic Letters. 6: 4411-4. PMID 15548038 DOI: 10.1021/ol0483293  1
2004 Woll MG, Gellman SH. Backbone thioester exchange: a new approach to evaluating higher order structural stability in polypeptides. Journal of the American Chemical Society. 126: 11172-4. PMID 15355097 DOI: 10.1021/ja046891i  1
2004 Lai JR, Fisk JD, Weisblum B, Gellman SH. Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface. Journal of the American Chemical Society. 126: 10514-5. PMID 15327289 DOI: 10.1021/ja047710f  1
2004 Epand RF, Raguse TL, Gellman SH, Epand RM. Antimicrobial 14-helical beta-peptides: potent bilayer disrupting agents. Biochemistry. 43: 9527-35. PMID 15260496 DOI: 10.1021/bi049414l  1
2004 Schmitt MA, Weisblum B, Gellman SH. Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones. Journal of the American Chemical Society. 126: 6848-9. PMID 15174837 DOI: 10.1021/ja048546z  1
2004 Langenhan JM, Gellman SH. Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in beta-peptide hairpins. Organic Letters. 6: 937-40. PMID 15012069 DOI: 10.1021/ol0364430  1
2004 Gelman MA, Weisblum B, Lynn DM, Gellman SH. Biocidal activity of polystyrenes that are cationic by virtue of protonation. Organic Letters. 6: 557-60. PMID 14961622 DOI: 10.1021/ol036341+  1
2004 Hayen A, Schmitt MA, Ngassa FN, Thomasson KA, Gellman SH. Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides. Angewandte Chemie (International Ed. in English). 43: 505-10. PMID 14735547 DOI: 10.1002/anie.200352125  1
2003 Huck BR, Fisk JD, Guzei IA, Carlson HA, Gellman SH. Secondary structural preferences of 2,2-disubstituted pyrrolidine-4-carboxylic acid oligomers: beta-peptide foldamers that cannot form internal hydrogen bonds. Journal of the American Chemical Society. 125: 9035-7. PMID 15369358 DOI: 10.1021/ja034561c  1
2003 Potocky TB, Menon AK, Gellman SH. Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells. The Journal of Biological Chemistry. 278: 50188-94. PMID 14517218 DOI: 10.1074/jbc.M308719200  1
2003 Gelman MA, Richter S, Cao H, Umezawa N, Gellman SH, Rana TM. Selective binding of TAR RNA by a Tat-derived beta-peptide. Organic Letters. 5: 3563-5. PMID 14507173 DOI: 10.1021/ol034977v  1
2003 Langenhan JM, Gellman SH. Preparation of protected syn-alpha,beta-dialkyl beta-amino acids that contain polar side chain functionality. The Journal of Organic Chemistry. 68: 6440-3. PMID 12895085 DOI: 10.1021/jo034583h  1
2003 Park JS, Lee HS, Lai JR, Kim BM, Gellman SH. Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold. Journal of the American Chemical Society. 125: 8539-45. PMID 12848561 DOI: 10.1021/ja034180z  1
2003 Langenhan JM, Guzei IA, Gellman SH. Parallel sheet secondary structure in beta-peptides. Angewandte Chemie (International Ed. in English). 42: 2402-5. PMID 12783508 DOI: 10.1002/anie.200350932  1
2003 Raguse TL, Lai JR, Gellman SH. Environment-independent 14-helix formation in short beta-peptides: striking a balance between shape control and functional diversity. Journal of the American Chemical Society. 125: 5592-3. PMID 12733872 DOI: 10.1021/ja0341485  1
2003 Eldred SE, Stone DA, Gellman SH, Stahl SS. Catalytic transamidation under moderate conditions. Journal of the American Chemical Society. 125: 3422-3. PMID 12643691 DOI: 10.1021/ja028242h  1
2003 Epand RF, Umezawa N, Porter EA, Gellman SH, Epand RM. Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. European Journal of Biochemistry / Febs. 270: 1240-8. PMID 12631282 DOI: 10.1046/j.1432-1033.2003.03484.x  1
2003 Lai JR, Gellman SH. Reinvestigation of the proposed folding and self-association of the Neuropeptide Head Activator. Protein Science : a Publication of the Protein Society. 12: 560-6. PMID 12592026 DOI: 10.1110/ps.0232103  1
2003 Lee HS, Park JS, Kim BM, Gellman SH. Efficient synthesis of enantiomerically pure beta2-amino acids via chiral isoxazolidinones. The Journal of Organic Chemistry. 68: 1575-8. PMID 12585907 DOI: 10.1021/jo026738b  1
2003 Syud FA, Stanger HE, Mortell HS, Espinosa JF, Fisk JD, Fry CG, Gellman SH. Influence of strand number on antiparallel beta-sheet stability in designed three- and four-stranded beta-sheets. Journal of Molecular Biology. 326: 553-68. PMID 12559922 DOI: 10.1016/S0022-2836(02)01304-9  1
2002 Raguse TL, Porter EA, Weisblum B, Gellman SH. Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency. Journal of the American Chemical Society. 124: 12774-85. PMID 12392424  1
2002 Woll MG, Fisk JD, LePlae PR, Gellman SH. Stereoselective synthesis of 3-substituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into short 12-helical beta-peptides that fold in water. Journal of the American Chemical Society. 124: 12447-52. PMID 12381185 DOI: 10.1021/ja0258778  1
2002 Lai JR, Huck BR, Weisblum B, Gellman SH. Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues. Biochemistry. 41: 12835-42. PMID 12379126 DOI: 10.1021/bi026127d  1
2002 Porter EA, Wang X, Schmitt MA, Gellman SH. Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline. Organic Letters. 4: 3317-9. PMID 12227778  1
2002 Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. Journal of the American Chemical Society. 124: 8522-3. PMID 12121081 DOI: 10.1021/ja026114n  1
2002 Porter EA, Weisblum B, Gellman SH. Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides. Journal of the American Chemical Society. 124: 7324-30. PMID 12071741 DOI: 10.1021/ja0260871  1
2002 LePlae PR, Fisk JD, Porter EA, Weisblum B, Gellman SH. Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications. Journal of the American Chemical Society. 124: 6820-1. PMID 12059191 DOI: 10.1021/ja017869h  1
2002 Gellman SH, Woolfson DN. Mini-proteins Trp the light fantastic. Nature Structural Biology. 9: 408-10. PMID 12032551 DOI: 10.1038/nsb0602-408  0.52
2002 Espinosa JF, Syud FA, Gellman SH. Analysis of the factors that stabilize a designed two-stranded antiparallel beta-sheet. Protein Science : a Publication of the Protein Society. 11: 1492-505. PMID 12021448 DOI: 10.1110/ps.4140102  1
2002 Hilario J, Kubelka J, Syud FA, Gellman SH, Keiderling TA. Spectroscopic characterization of selected beta- sheet hairpin models. Biopolymers. 67: 233-6. PMID 12012436 DOI: 10.1002/bip.10094  1
2002 Umezawa N, Gelman MA, Haigis MC, Raines RT, Gellman SH. Translocation of a beta-peptide across cell membranes. Journal of the American Chemical Society. 124: 368-9. PMID 11792194 DOI: 10.1021/ja017283v  1
2002 Knight SM, Umezawa N, Lee HS, Gellman SH, Kay BK. A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. Analytical Biochemistry. 300: 230-6. PMID 11779115 DOI: 10.1006/abio.2001.5468  1
2001 Raguse TL, Lai JR, LePlae PR, Gellman SH. Toward beta-peptide tertiary structure: self-association of an amphiphilic 14-helix in aqueous solution. Organic Letters. 3: 3963-6. PMID 11720580 DOI: 10.1021/ol016868r  1
2001 Cheng RP, Gellman SH, DeGrado WF. beta-Peptides: from structure to function. Chemical Reviews. 101: 3219-32. PMID 11710070  0.32
2001 Woll MG, Lai JR, Guzei IA, Taylor SJ, Smith ME, Gellman SH. Parallel sheet secondary structure in gamma-peptides. Journal of the American Chemical Society. 123: 11077-8. PMID 11686719 DOI: 10.1021/ja011719p  1
2001 Stanger HE, Syud FA, Espinosa JF, Giriat I, Muir T, Gellman SH. Length-dependent stability and strand length limits in antiparallel beta -sheet secondary structure. Proceedings of the National Academy of Sciences of the United States of America. 98: 12015-20. PMID 11593011 DOI: 10.1073/pnas.211536998  1
2001 Syud FA, Stanger HE, Gellman SH. Interstrand side chain--side chain interactions in a designed beta-hairpin: significance of both lateral and diagonal pairings. Journal of the American Chemical Society. 123: 8667-77. PMID 11535071 DOI: 10.1021/ja0109803  1
2001 LePlae PR, Umezawa N, Lee HS, Gellman SH. An efficient route to either enantiomer of trans-2-aminocyclopentanecarboxylic acid. The Journal of Organic Chemistry. 66: 5629-32. PMID 11485497 DOI: 10.1021/jo010279h  1
2001 Langenhan JM, Fisk JD, Gellman SH. Evaluation of hydrogen bonding complementarity between a secondary sulfonamide and an alpha-amino acid residue. Organic Letters. 3: 2559-62. PMID 11483060 DOI: 10.1021/ol016237x  1
2001 Lee HS, Syud FA, Wang X, Gellman SH. Diversity in short beta-peptide 12-helices: high-resolution structural analysis in aqueous solution of a hexamer containing sulfonylated pyrrolidine residues. Journal of the American Chemical Society. 123: 7721-2. PMID 11481004 DOI: 10.1021/ja010734r  1
2001 McKay SL, Haptonstall B, Gellman SH. Beyond the hydrophobic effect: attractions involving heteroaromatic rings in aqueous solution. Journal of the American Chemical Society. 123: 1244-5. PMID 11456685 DOI: 10.1021/ja003256d  1
2001 Fisk JD, Gellman SH. A parallel beta-sheet model system that folds in water. Journal of the American Chemical Society. 123: 343-4. PMID 11456526 DOI: 10.1021/ja002493d  0.96
2001 Lee HS, LePlae PR, Porter EA, Gellman SH. An efficient route to either enantiomer of orthogonally protected trans-3-aminopyrrolidine-4-carboxylic acid. The Journal of Organic Chemistry. 66: 3597-9. PMID 11348151 DOI: 10.1021/jo001534l  1
2001 Espinosa JF, Muñoz V, Gellman SH. Interplay between hydrophobic cluster and loop propensity in beta-hairpin formation. Journal of Molecular Biology. 306: 397-402. PMID 11178900 DOI: 10.1006/jmbi.2000.4349  0.76
2000 Yu SM, McQuade DT, Quinn MA, Hackenberger CP, Krebs MP, Polans AS, Gellman SH. An improved tripod amphiphile for membrane protein solubilization. Protein Science : a Publication of the Protein Society. 9: 2518-27. PMID 11206073 DOI: 10.1110/ps.9.12.2518  1
2000 Huck BR, Fisk JD, Gellman SH. Promotion of sheet formation in alpha-peptide strands by a beta-peptide reverse turn. Organic Letters. 2: 2607-10. PMID 10990408  1
2000 Appella DH, LePlae PR, Raguse TL, Gellman SH. (R,R,R)-2,5-diaminocylohexanecarboxylic acid, a building block for water-soluble, helix-forming beta-peptides. The Journal of Organic Chemistry. 65: 4766-9. PMID 10959893 DOI: 10.1021/jo000277h  1
2000 Espinosa JF, Gellman SH. A Designed beta-Hairpin Containing a Natural Hydrophobic Cluster This research was supported by the National Science Foundation (CHE-9820952). J.F.E. was supported by a fellowship from the Ministerio de Educacion y Cultura (Spain) and the Fulbright Commission. The mass spectrometer was purchased in part with a National Science Foundation grant (CHE-9520868), and the NMR spectrometers were purchased in part with a National Institute Of Health grant (1 S10 RR04981). The CD spectrometer and analytical ultracentrifuge are part of the UW Biophysics Instrumentation Facility (NSF BIR-9512577). Angewandte Chemie (International Ed. in English). 39: 2330-2333. PMID 10941081 DOI: 10.1002/1521-3773(20000703)39:13<2330::AID-ANIE2330>3.0.CO;2-C  0.76
2000 Gardner RR, McKay SL, Gellman SH. Solvent-dependent stabilization of the E configuration of propargylic secondary amides. Organic Letters. 2: 2335-8. PMID 10930277  1
2000 Porter EA, Wang X, Lee HS, Weisblum B, Gellman SH. Non-haemolytic beta-amino-acid oligomers. Nature. 404: 565. PMID 10766230 DOI: 10.1038/35007145  1
2000 McQuade DT, Quinn MA, Yu SM, Polans AS, Krebs MP, Gellman SH. Rigid Amphiphiles for Membrane Protein Manipulation. Angewandte Chemie (International Ed. in English). 39: 758-761. PMID 10760860 DOI: 10.1002/(SICI)1521-3773(20000218)39:4<758::AID-ANIE758>3.0.CO;2-V  0.64
1999 Huck BR, Langenhan JM, Gellman SH. Non-hydrogen-bonded secondary structure in beta-peptides: evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers. Organic Letters. 1: 1717-20. PMID 10836030  1
1998 Daugherty DL, Rozema D, Hanson PE, Gellman SH. Artificial chaperone-assisted refolding of citrate synthase. The Journal of Biological Chemistry. 273: 33961-71. PMID 9852049 DOI: 10.1074/jbc.273.51.33961  0.8
1997 Appella DH, Christianson LA, Klein DA, Powell DR, Huang X, Barchi JJ, Gellman SH. Residue-based control of helix shape in β-peptide oligomers Nature. 387: 381-384. PMID 9163422 DOI: 10.1038/387381a0  1
1996 Rozema D, Gellman SH. Artificial chaperone-assisted refolding of denatured-reduced lysozyme: modulation of the competition between renaturation and aggregation. Biochemistry. 35: 15760-71. PMID 8961939 DOI: 10.1021/bi961638j  0.8
1996 Rozema D, Gellman SH. Artificial chaperone-assisted refolding of carbonic anhydrase B. The Journal of Biological Chemistry. 271: 3478-87. PMID 8631951  0.8
1992 Liang GB, Rito CJ, Gellman SH. Variations in the turn-forming characteristics of N-acyl proline units. Biopolymers. 32: 293-301. PMID 1581548 DOI: 10.1002/bip.360320309  0.56
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