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Scott D. Rychnovsky - Publications

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Organic Chemistry, Synthesis and Structure Determination
Website:
http://www.faculty.uci.edu/profile.cfm?faculty_id=2092

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wheat A, Yu C, Wang X, Burke AM, Chemmama IE, Kaake RM, Baker P, Rychnovsky SD, Yang J, Huang L. Protein interaction landscapes revealed by advanced in vivo cross-linking-mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34349018 DOI: 10.1073/pnas.2023360118  0.58
2019 Rychnovsky S, Burtea A, DeForest J, Li X. Total Synthesis of (-)-Himeradine A. Angewandte Chemie (International Ed. in English). PMID 31491044 DOI: 10.1002/Anie.201910129  0.464
2018 DeForest JC, Samame RA, Suryn G, Burtea A, Rychnovsky SD. Second-Generation Synthesis of (+)-Fastigiatine Inspired by Conformational Studies. The Journal of Organic Chemistry. PMID 29943989 DOI: 10.1021/Acs.Joc.8B01144  0.826
2018 Brito GA, Della-Felice F, Luo G, Burns AS, Pilli RA, Rychnovsky SD, Krische MJ. Catalytic Enantioselective Allylations of Acetylenic Aldehydes via 2-Propanol-Mediated Reductive Coupling. Organic Letters. PMID 29938513 DOI: 10.1021/Acs.Orglett.8B01776  0.395
2017 Burns AS, Wagner AJ, Fulton JL, Young K, Zakarian A, Rychnovsky SD. Determination of the Absolute Configuration of β-Chiral Primary Alcohols Using the Competing Enantioselective Conversion Method. Organic Letters. PMID 28508638 DOI: 10.1021/Acs.Orglett.7B01189  0.323
2016 Samame RA, Owens CM, Rychnovsky SD. Concise synthesis of (+)-fastigiatine. Chemical Science. 7: 188-190. PMID 28966768 DOI: 10.1039/C5Sc03262H  0.812
2016 Hilf JA, Holzwarth MS, Rychnovsky SD. Route to Highly Substituted Pyridines. The Journal of Organic Chemistry. PMID 27579766 DOI: 10.1021/Acs.Joc.6B01370  0.812
2016 Bisen S, Seleverstov O, Belani J, Rychnovsky S, Dopico AM, Bukiya AN. Distinct mechanisms underlying cholesterol protection against alcohol-induced BK channel inhibition and resulting vasoconstriction. Biochimica Et Biophysica Acta. 1861: 1756-1766. PMID 27565113 DOI: 10.1016/J.Bbalip.2016.08.013  0.717
2016 Wagner AJ, Miller SM, King RP, Rychnovsky SD. Nanomole-Scale Assignment and One-Use Kits for Determining the Absolute Configuration of Secondary Alcohols. The Journal of Organic Chemistry. PMID 27415613 DOI: 10.1021/Acs.Joc.6B00816  0.376
2016 Tay GC, Sizemore N, Rychnovsky SD. Stereoselection in Intramolecular Diels-Alder Reactions of 2-Cyano-1-azadienes: Indolizidine and Quinolizidine Synthesis. Organic Letters. PMID 27295460 DOI: 10.1021/Acs.Orglett.6B00881  0.438
2015 Yu C, Mao H, Novitsky EJ, Tang X, Rychnovsky SD, Zheng N, Huang L. Gln40 deamidation blocks structural reconfiguration and activation of SCF ubiquitin ligase complex by Nedd8. Nature Communications. 6: 10053. PMID 26632597 DOI: 10.1038/Ncomms10053  0.3
2015 Kandur WV, Kao A, Vellucci D, Huang L, Rychnovsky SD. Design of CID-cleavable protein cross-linkers: identical mass modifications for simpler sequence analysis. Organic & Biomolecular Chemistry. 13: 9793-807. PMID 26269432 DOI: 10.1039/C5Ob01410G  0.763
2015 Perry MA, Hill RR, Leong JJ, Rychnovsky SD. Stereochemical Outcomes in Reductive Cyclizations To Form Spirocyclic Heterocycles. Organic Letters. 17: 3268-71. PMID 26087830 DOI: 10.1021/Acs.Orglett.5B01422  0.805
2015 Burke AM, Kandur W, Novitsky EJ, Kaake RM, Yu C, Kao A, Vellucci D, Huang L, Rychnovsky SD. Synthesis of two new enrichable and MS-cleavable cross-linkers to define protein-protein interactions by mass spectrometry. Organic & Biomolecular Chemistry. 13: 5030-7. PMID 25823605 DOI: 10.1039/C5Ob00488H  0.769
2015 Perry MA, Rychnovsky SD. Generation, structure and reactivity of tertiary organolithium reagents. Natural Product Reports. 32: 517-33. PMID 25475042 DOI: 10.1039/C4Np00125G  0.654
2015 Samame RA, Owens CM, Rychnovsky SD. Concise synthesis of (+)-fastigiatine Chemical Science. 7: 188-190. DOI: 10.1039/c5sc03262h  0.815
2014 Kaake RM, Wang X, Burke A, Yu C, Kandur W, Yang Y, Novtisky EJ, Second T, Duan J, Kao A, Guan S, Vellucci D, Rychnovsky SD, Huang L. A new in vivo cross-linking mass spectrometry platform to define protein-protein interactions in living cells. Molecular & Cellular Proteomics : McP. 13: 3533-43. PMID 25253489 DOI: 10.1074/Mcp.M114.042630  0.762
2014 Tay GC, Huang CY, Rychnovsky SD. Silyl enol ether Prins cyclization: diastereoselective formation of substituted tetrahydropyran-4-ones. The Journal of Organic Chemistry. 79: 8733-49. PMID 25200563 DOI: 10.1021/Jo501580P  0.465
2014 Yu C, Kandur W, Kao A, Rychnovsky S, Huang L. Developing new isotope-coded mass spectrometry-cleavable cross-linkers for elucidating protein structures. Analytical Chemistry. 86: 2099-106. PMID 24471733 DOI: 10.1021/Ac403636B  0.771
2014 Wagner AJ, Miller SM, Nguyen S, Lee GY, Rychnovsky SD, Link RD. Undergraduate laboratory experiment to determine absolute configuration using thin-layer chromatography Journal of Chemical Education. 91: 716-721. DOI: 10.1021/Ed4004996  0.359
2013 Wagner AJ, Rychnovsky SD. Kinetic analysis of the HBTM-catalyzed esterification of an enantiopure secondary alcohol. Organic Letters. 15: 5504-7. PMID 24128066 DOI: 10.1021/Ol402643N  0.322
2013 Tay GC, Gesinski MR, Rychnovsky SD. Formation of highly substituted tetrahydropyranones: application to the total synthesis of cyanolide A. Organic Letters. 15: 4536-9. PMID 23962271 DOI: 10.1021/Ol402095G  0.834
2013 Myers BR, Sever N, Chong YC, Kim J, Belani JD, Rychnovsky S, Bazan JF, Beachy PA. Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response. Developmental Cell. 26: 346-57. PMID 23954590 DOI: 10.1016/J.Devcel.2013.07.015  0.721
2013 Perry MA, Hill RR, Rychnovsky SD. Trianion synthon approach to spirocyclic heterocycles. Organic Letters. 15: 2226-9. PMID 23594129 DOI: 10.1021/Ol400788Q  0.63
2013 Cleary L, Mak VW, Rychnovsky SD, Shea KJ, Sizemore N. Origins of regio- and stereochemistry in type 2 intramolecular N-acylnitroso Diels-Alder reactions: a computational study of tether length and substituent effects. The Journal of Organic Chemistry. 78: 4090-8. PMID 23477601 DOI: 10.1021/Jo4004025  0.382
2013 Perry MA, Trinidad JV, Rychnovsky SD. Absolute configuration of lactams and oxazolidinones using kinetic resolution catalysts. Organic Letters. 15: 472-5. PMID 23323958 DOI: 10.1021/Ol303239T  0.584
2012 Miller SM, Samame RA, Rychnovsky SD. Nanomole-scale assignment of configuration for primary amines using a kinetic resolution strategy. Journal of the American Chemical Society. 134: 20318-21. PMID 23210977 DOI: 10.1021/Ja310620C  0.78
2012 Kristiana I, Luu W, Stevenson J, Cartland S, Jessup W, Belani JD, Rychnovsky SD, Brown AJ. Cholesterol through the looking glass: ability of its enantiomer also to elicit homeostatic responses. The Journal of Biological Chemistry. 287: 33897-904. PMID 22869373 DOI: 10.1074/Jbc.M112.360537  0.717
2012 Kao A, Randall A, Yang Y, Patel VR, Kandur W, Guan S, Rychnovsky SD, Baldi P, Huang L. Mapping the structural topology of the yeast 19S proteasomal regulatory particle using chemical cross-linking and probabilistic modeling. Molecular & Cellular Proteomics : McP. 11: 1566-77. PMID 22550050 DOI: 10.1074/Mcp.M112.018374  0.783
2012 Perry MA, Morin MD, Slafer BW, Rychnovsky SD. Total synthesis of lepadiformine alkaloids using N-Boc α-amino nitriles as trianion synthons. The Journal of Organic Chemistry. 77: 3390-400. PMID 22413935 DOI: 10.1021/Jo300161X  0.826
2011 Reilly MK, Rychnovsky SD. DABO Boronates: Stable Heterocyclic Boronic Acid Complexes for Use in Suzuki-Miyaura Cross-Coupling Reactions. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2011. PMID 24371372 DOI: 10.1055/S-0030-1261218  0.736
2011 Wagner AJ, David JG, Rychnovsky SD. Determination of absolute configuration using kinetic resolution catalysts. Organic Letters. 13: 4470-3. PMID 21776975 DOI: 10.1021/Ol201902Y  0.304
2011 Gesinski MR, Rychnovsky SD. Total synthesis of the cyanolide A aglycon. Journal of the American Chemical Society. 133: 9727-9. PMID 21639102 DOI: 10.1021/Ja204228Q  0.83
2011 Bukiya AN, Belani JD, Rychnovsky S, Dopico AM. Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions. The Journal of General Physiology. 137: 93-110. PMID 21149543 DOI: 10.1085/Jgp.201010519  0.725
2011 Kao A, Chiu CL, Vellucci D, Yang Y, Patel VR, Guan S, Randall A, Baldi P, Rychnovsky SD, Huang L. Development of a novel cross-linking strategy for fast and accurate identification of cross-linked peptides of protein complexes. Molecular & Cellular Proteomics : McP. 10: M110.002212. PMID 20736410 DOI: 10.1074/Mcp.M110.002212  0.775
2011 Bukiya AN, Belani JD, Rychnovsky S, Dopico AM. Correction: Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions Journal of General Physiology. 137: 391. DOI: 10.1085/jgp.2010105191374c  0.693
2010 Reilly MK, Rychnovsky SD. Allyl transfer to aldehydes and ketones by Brønsted acid activation of allyl and crotyl 1,3,2-dioxazaborolidines. Organic Letters. 12: 4892-5. PMID 20942379 DOI: 10.1021/Ol1020515  0.739
2010 Perry MA, Morin MD, Slafer BW, Wolckenhauer SA, Rychnovsky SD. Fully substituted carbon centers by diastereoselective spirocyclization: stereoselective synthesis of (+)-lepadiformine C. Journal of the American Chemical Society. 132: 9591-3. PMID 20578697 DOI: 10.1021/Ja104250B  0.803
2010 Vellucci D, Kao A, Kaake RM, Rychnovsky SD, Huang L. Selective enrichment and identification of azide-tagged cross-linked peptides using chemical ligation and mass spectrometry. Journal of the American Society For Mass Spectrometry. 21: 1432-45. PMID 20472459 DOI: 10.1016/J.Jasms.2010.04.004  0.785
2010 Nakamura Y, Burke AM, Kotani S, Ziller JW, Rychnovsky SD. Total synthesis of (-)-lycoperine A. Organic Letters. 12: 72-5. PMID 19947619 DOI: 10.1021/Ol902389E  0.642
2010 Nakamura Y, Burke AM, Kotani S, Ziller JW, Rychnovsky SD. Synthesis of (-)-Lycoperine A Synfacts. 2010: 505-505. DOI: 10.1055/S-0029-1219713  0.414
2010 Bukiya AN, Singh AK, Belani JD, Rychnovsky S, Dopico AM. Strict Structural Requirements for Cholesterol to Inhibit BK Channels Point to Specific Steroid-Protein Interactions Biophysical Journal. 98: 622a. DOI: 10.1016/J.Bpj.2009.12.3405  0.728
2010 EVANS DA, BARROW JC, WATSON PS, RATZ AM, DINSMORE CJ, EVRARD DA, DE VRIES KM, ELLMAN JA, RYCHNOVSKY SD, LACOUR J. ChemInform Abstract: Approaches to the Synthesis of the Vancomycin Antibiotics. Synthesis of Orienticin C (Bis-dechlorovancomycin) Aglycon (I). Cheminform. 28: no-no. DOI: 10.1002/chin.199734282  0.701
2010 EVANS DA, EVRARD DA, RYCHNOVSKY SD, FRUEH T, WHITTINGHAM WG, DEVRIES KM. ChemInform Abstract: A General Approach to the Asymmetric Synthesis of Vancomycin-Related Arylglycines by Enolate Azidation. Cheminform. 23: no-no. DOI: 10.1002/chin.199241229  0.433
2009 Gesinski MR, Tadpetch K, Rychnovsky SD. Symmetric macrocycles by a Prins dimerization and macrocyclization strategy. Organic Letters. 11: 5342-5. PMID 19873984 DOI: 10.1021/Ol9022062  0.807
2009 Malathong V, Rychnovsky SD. Polyol synthesis with beta-oxyanionic alkyllithium reagents: syntheses of aculeatins A, B, and D. Organic Letters. 11: 4220-3. PMID 19691310 DOI: 10.1021/Ol901623H  0.794
2009 Bahde RJ, Rychnovsky SD. ChemInform Abstract: Cyclization via Carbolithiation of α-Amino Alkyllithium Reagents. Cheminform. 40. DOI: 10.1002/chin.200904135  0.79
2008 Gesinski MR, Van Orden LJ, Rychnovsky SD. Lewis Acid-Promoted Mukaiyama Aldol-Prins (MAP) Cyclizations of Acetals, Ketals, α-Acetoxy Ethers, and Orthoformates. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2008: 363-366. PMID 20936058 DOI: 10.1055/S-2008-1032053  0.796
2008 Tadpetch K, Rychnovsky SD. Rhenium(VII) catalysis of Prins cyclization reactions. Organic Letters. 10: 4839-42. PMID 18816133 DOI: 10.1021/Ol8019204  0.796
2008 Bahnck KB, Rychnovsky SD. Formal synthesis of (-)-kendomycin featuring a Prins-cyclization to construct the macrocycle. Journal of the American Chemical Society. 130: 13177-81. PMID 18767844 DOI: 10.1021/Ja805187P  0.833
2008 Bahde RJ, Rychnovsky SD. Cyclization via carbolithiation of alpha-amino alkyllithium reagents. Organic Letters. 10: 4017-20. PMID 18700774 DOI: 10.1021/Ol801523R  0.798
2008 Cheung LL, Marumoto S, Anderson CD, Rychnovsky SD. Assignment of absolute configuration to SCH 351448 via total synthesis. Organic Letters. 10: 3101-4. PMID 18543942 DOI: 10.1021/Ol8011474  0.8
2008 Belani JD, Rychnovsky SD. A concise synthesis of ent-Cholesterol. The Journal of Organic Chemistry. 73: 2768-73. PMID 18336043 DOI: 10.1021/Jo702694G  0.768
2008 Belani JD, Rychnovsky SD. Synthesis of ent-Cholesterol Synfacts. 2008: 790-790. DOI: 10.1055/S-2008-1077897  0.755
2008 Gesinski MR, Van Orden LJ, Rychnovsky SD. Lewis acid promoted Mukaiyama aldol-Prins (MAP) cyclizations of acetals, ketals, α-acetoxy ethers, and orthoformates Synlett. 363-366. DOI: 10.1055/s-2008-1032053  0.781
2008 Cerf E, Gasper R, Belani JD, Rychnovsky S, Chang Xb, Buyse F, Ruysschaert JM. Corrigendum to "Multidrug resistance protein 1 is not associated to detergent-resistant membranes" [Biochem. Biophys. Res. Commun. 355 (2007) 1025-1030] (DOI:10.1016/j.bbrc.2007.02.075) Biochemical and Biophysical Research Communications. 366: 605. DOI: 10.1016/J.Bbrc.2007.12.016  0.704
2007 Epand RM, Shulga YV, Timmons HC, Perri AL, Belani JD, Perinpanathan K, Johnson-McIntire LB, Bajjalieh S, Dicu AO, Elias C, Rychnovsky SD, Topham MK. Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. Biochemistry. 46: 14225-31. PMID 18004883 DOI: 10.1021/Bi701584V  0.72
2007 Tian X, Rychnovsky SD. Synthesis and structural reassignment of (+)-epicalyxin F. Organic Letters. 9: 4955-8. PMID 17958435 DOI: 10.1021/Ol702200T  0.512
2007 Huckins JR, de Vicente J, Rychnovsky SD. Synthesis of the C1-C52 fragment of amphidinol 3, featuring a beta-alkoxy alkyllithium addition reaction. Organic Letters. 9: 4757-60. PMID 17944478 DOI: 10.1021/Ol7020934  0.804
2007 Van Orden LJ, Patterson BD, Rychnovsky SD. Total synthesis of leucascandrolide a: a new application of the Mukaiyama aldol-Prins reaction. The Journal of Organic Chemistry. 72: 5784-93. PMID 17595145 DOI: 10.1021/Jo070901R  0.823
2007 La Cruz TE, Rychnovsky SD. A reductive cyclization approach to attenol A. The Journal of Organic Chemistry. 72: 2602-11. PMID 17346087 DOI: 10.1021/Jo0626459  0.822
2007 Cerf E, Gasper R, Belani JD, Rychnovsky S, Chang XB, Buyse F, Ruysschaert JM. Multidrug resistance protein 1 is not associated to detergent-resistant membranes. Biochemical and Biophysical Research Communications. 355: 1025-30. PMID 17336270 DOI: 10.1016/J.Bbrc.2007.02.075  0.716
2007 Vellucci D, Rychnovsky SD. Diastereoselective synthesis of the pectenotoxin 2 non-anomeric AB spiroacetal. Organic Letters. 9: 711-4. PMID 17286378 DOI: 10.1021/Ol0630447  0.826
2007 Porco, Jr. J, Su S, Lei X, Bardhan S, Rychnovsky S. Synthesis of (+)-Hexacyclinol Synfacts. 2007: 0119-0119. DOI: 10.1055/S-2006-955760  0.414
2006 Loening NM, Anderson CE, Iskenderian WS, Anderson CD, Rychnovsky SD, Barfield M, O'Leary DJ. Qualitative and quantitative measurements of hydrogen bond mediated scalar couplings in acyclic 1,3-diols. Organic Letters. 8: 5321-3. PMID 17078708 DOI: 10.1021/Ol062121V  0.445
2006 Jasti R, Rychnovsky SD. Racemization in Prins cyclization reactions. Journal of the American Chemical Society. 128: 13640-8. PMID 17031979 DOI: 10.1021/Ja064783L  0.667
2006 de Vicente J, Huckins JR, Rychnovsky SD. Synthesis of the C31-C67 fragment of amphidinol 3. Angewandte Chemie (International Ed. in English). 45: 7258-62. PMID 17013953 DOI: 10.1002/Anie.200602742  0.788
2006 Porco JA, Su S, Lei X, Bardhan S, Rychnovsky SD. Total synthesis and structure assignment of (+)-hexacyclinol. Angewandte Chemie (International Ed. in English). 45: 5790-2. PMID 16871643 DOI: 10.1002/Anie.200602854  0.577
2006 Bahnck KB, Rychnovsky SD. Rapid stereocontrolled assembly of the fully substituted C-aryl glycoside of kendomycin with a Prins cyclization: a formal synthesis. Chemical Communications (Cambridge, England). 2388-90. PMID 16733589 DOI: 10.1039/B602937J  0.813
2006 Jasti R, Rychnovsky SD. Solvolysis of a tetrahydropyranyl mesylate: mechanistic implications for the Prins cyclization, 2-oxonia-cope rearrangement, and Grob fragmentation. Organic Letters. 8: 2175-8. PMID 16671810 DOI: 10.1021/Ol0606738  0.689
2006 Tian X, Jaber JJ, Rychnovsky SD. Synthesis and structure revision of calyxin natural products. The Journal of Organic Chemistry. 71: 3176-83. PMID 16599616 DOI: 10.1021/Jo060094G  0.764
2006 La Cruz TE, Rychnovsky SD. Stereoselectivity of intramolecular SN' cyclizations of alkyllithium reagents on methoxy alkenes. The Journal of Organic Chemistry. 71: 1068-73. PMID 16438522 DOI: 10.1021/Jo052166U  0.819
2006 Rychnovsky S, Tian X, Jaber J. Synthesis of Calyxin L Synfacts. 2006: 0978-0978. DOI: 10.1055/s-2006-949315  0.429
2005 Anderson CE, Britt DK, Sangji S, O'Leary DJ, Anderson CD, Rychnovsky SD. Direct assignment of the relative configuration in acyclic 1,3-diols by 1H NMR spectroscopy. Organic Letters. 7: 5721-3. PMID 16321031 DOI: 10.1021/Ol052539D  0.483
2005 Bolla ML, Patterson B, Rychnovsky SD. Tetrahydropyran rings from a Mukaiyama-Michael cascade reaction. Journal of the American Chemical Society. 127: 16044-5. PMID 16287289 DOI: 10.1021/Ja056483U  0.822
2005 Anderson CD, Shea KJ, Rychnovsky SD. Strategies for the generation of molecularly imprinted polymeric nitroxide catalysts. Organic Letters. 7: 4879-82. PMID 16235912 DOI: 10.1021/Ol051749N  0.485
2005 Xu F, Rychnovsky SD, Belani JD, Hobbs HH, Cohen JC, Rawson RB. Dual roles for cholesterol in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 14551-6. PMID 16199524 DOI: 10.1073/Pnas.0503590102  0.726
2005 Vitale JP, Wolckenhauer SA, Do NM, Rychnovsky SD. Synthesis of the C3-C19 segment of phorboxazole B. Organic Letters. 7: 3255-8. PMID 16018634 DOI: 10.1021/Ol051039H  0.797
2005 Jasti R, Anderson CD, Rychnovsky SD. Utilization of an oxonia-Cope rearrangement as a mechanistic probe for Prins cyclizations. Journal of the American Chemical Society. 127: 9939-45. PMID 15998101 DOI: 10.1021/Ja0518326  0.724
2005 Epand RM, Rychnovsky SD, Belani JD, Epand RF. Role of chirality in peptide-induced formation of cholesterol-rich domains. The Biochemical Journal. 390: 541-8. PMID 15929726 DOI: 10.1042/Bj20050649  0.73
2005 Morin MD, Rychnovsky SD. Reductive spiroannulation of nitriles with secondary electrophiles. Organic Letters. 7: 2051-3. PMID 15876052 DOI: 10.1021/Ol050567Q  0.784
2005 La Cruz TE, Rychnovsky SD. Synthesis of the spirofungin B core by a reductive cyclization strategy. Organic Letters. 7: 1873-5. PMID 15844928 DOI: 10.1021/Ol050589C  0.819
2005 Dalgard JE, Rychnovsky SD. Enantioselective synthesis of the C18-C25 segment of lasonolide A by an oxonia-cope prins cascade. Organic Letters. 7: 1589-91. PMID 15816759 DOI: 10.1021/Ol050270S  0.819
2005 Takaoka LR, Buckmelter AJ, LaCruz TE, Rychnovsky SD. Rational synthesis of contra-thermodynamic spiroacetals by reductive cyclizations. Journal of the American Chemical Society. 127: 528-9. PMID 15643869 DOI: 10.1021/Ja044642O  0.827
2005 Graetz B, Rychnovsky S, Leu WH, Farmer P, Lin R. C2-Symmetric nitroxides and their potential as enantioselective oxidants Tetrahedron Asymmetry. 16: 3584-3598. DOI: 10.1016/J.Tetasy.2005.09.016  0.781
2005 Wolckenhauer SA, Rychnovsky SD. Stereochemical course of the reductive spiroannulations of N-Boc and N-benzyl 2-cyanopiperidines Tetrahedron. 61: 3371-3381. DOI: 10.1016/J.Tet.2005.01.099  0.788
2004 Dalgard JE, Rychnovsky SD. Oxonia-cope prins cyclizations: a facile method for the synthesis of tetrahydropyranones bearing quaternary centers. Journal of the American Chemical Society. 126: 15662-3. PMID 15571386 DOI: 10.1021/Ja044736Y  0.835
2004 Jasti R, Vitale J, Rychnovsky SD. Axial-selective prins cyclizations by solvolysis of alpha-bromo ethers. Journal of the American Chemical Society. 126: 9904-5. PMID 15303848 DOI: 10.1021/Ja046972E  0.819
2004 Wolckenhauer SA, Rychnovsky SD. Generation and utility of tertiary alpha-aminoorganolithium reagents. Organic Letters. 6: 2745-8. PMID 15281759 DOI: 10.1021/Ol049039P  0.808
2004 Dalgard JE, Rychnovsky SD. Memory of chirality in the transannular cyclization of cyclodecenyl radicals. Organic Letters. 6: 2713-6. PMID 15281751 DOI: 10.1021/Ol049038X  0.79
2004 Kadota I, Hu Y, Packard GK, Rychnovsky SD. A unified approach to polyene macrolides: synthesis of candidin and nystatin polyols. Proceedings of the National Academy of Sciences of the United States of America. 101: 11992-5. PMID 15192147 DOI: 10.1073/Pnas.0401552101  0.788
2004 Packard GK, Hu Y, Vescovi A, Rychnovsky SD. Synthesis of rimocidinolide methyl ester, the aglycone of (+)-rimocidin. Angewandte Chemie (International Ed. in English). 43: 2822-6. PMID 15150759 DOI: 10.1002/Anie.200453697  0.786
2004 La Cruz TE, Rychnovsky SD. Intramolecular S(N)2' cyclization of an alkyllithium species onto a methoxy allyl ether is syn selective. Chemical Communications (Cambridge, England). 168-9. PMID 14737532 DOI: 10.1039/B314358A  0.786
2004 Patterson B, Rychnovsky SD. Mukaiyama Aldol-Prins Cyclizations with Ketones Synlett. 543-545. DOI: 10.1055/S-2005-869848  0.414
2004 La Cruz TE, Rychnovsky SD. Application of hemithio ketene acetals to the synthesis of spirocyclic orthoesters Synlett. 2013-2015. DOI: 10.1055/S-2004-830874  0.827
2004 Jasti R, Vitale J, Rychnovsky SD. Axial-Selective Prins Cyclizations by Solvolysis of α-Bromo Ethers. Cheminform. 35. DOI: 10.1002/chin.200450095  0.792
2004 La Cruz TE, Rychnovsky SD. Intramolecular SN2′ cyclization of an alkyllithium species onto a methoxy allyl ether is syn selective Chemical Communications. 10: 168-169.  0.792
2003 Huckins JR, Rychnovsky SD. Synthesis of optically pure arylsilylcarbinols and their use as chiral auxiliaries in oxacarbenium ion reactions. The Journal of Organic Chemistry. 68: 10135-45. PMID 14682711 DOI: 10.1021/Jo035260O  0.806
2003 Graetz BR, Rychnovsky SD. Formal synthesis of (-)-apicularen A. Organic Letters. 5: 3357-60. PMID 12943426 DOI: 10.1021/Ol0353417  0.818
2003 Patterson B, Marumoto S, Rychnovsky SD. Titanium(IV)-promoted Mukaiyama aldol-Prins cyclizations. Organic Letters. 5: 3163-6. PMID 12917007 DOI: 10.1021/Ol035303N  0.424
2003 Rychnovsky SD, Cossrow J. Diastereoselective additions of nucleophiles to alpha-acetoxy ethers using the alpha-(trimethylsilyl)benzyl auxiliary. Organic Letters. 5: 2367-70. PMID 12816450 DOI: 10.1021/Ol0347904  0.807
2003 Kim AI, Rychnovsky SD. Unified strategy for the synthesis of (-)-elisapterosin B and (-)-colombiasin A. Angewandte Chemie (International Ed. in English). 42: 1267-70. PMID 12645060 DOI: 10.1002/Anie.200390325  0.627
2003 Rychnovsky SD, Takaoka LR. Spiroannulation by alkylation and reductive cyclization of nitriles. Angewandte Chemie (International Ed. in English). 42: 818-20. PMID 12596210 DOI: 10.1002/Anie.200390218  0.824
2003 Kopecky DJ, Rychnovsky SD. Preparation of α‐Acetoxy Ethers by the Reductive Acetylation of Esters: endo‐1‐Bornyloxyethyl Acetate Organic Syntheses. 80: 177-183. DOI: 10.1002/0471264180.Os080.20  0.722
2003 Kopecky DJ, Rychnovsky SD. Preparation of α-acetoxy ethers by the reductive acetylation of esters: Endo-1-bornyloxyethyl acetate (ethanol, 1-[[(1R,2S,4R)-1,7,7- trimethylbicyclo[2.2.1]hept-2-yl]oxy]-, acetate) Organic Syntheses. 80: 177-183.  0.639
2002 Marumoto S, Jaber JJ, Vitale JP, Rychnovsky SD. Synthesis of (-)-centrolobine by Prins cyclizations that avoid racemization. Organic Letters. 4: 3919-22. PMID 12599492 DOI: 10.1021/Ol026751I  0.826
2002 Anderson CD, Rychnovsky SD. Empirical model for the molar rotations of syn-2,2-dimethyl-1,3-dioxanes. Organic Letters. 4: 3075-8. PMID 12201720 DOI: 10.1021/Ol0263550  0.471
2002 Cossrow J, Rychnovsky SD. Optically pure alpha-(trimethylsilyl)benzyl alcohol: a practical chiral auxiliary for oxocarbenium ion reactions. Organic Letters. 4: 147-50. PMID 11772112 DOI: 10.1021/Ol017063M  0.805
2002 Sinz CJ, Rychnovsky SD. Total synthesis of the polyene macrolide dermostatin A Tetrahedron. 58: 6561-6576. DOI: 10.1016/S0040-4020(02)00666-X  0.782
2001 Sinz CJ, Rychnovsky SD. Total Synthesis of Dermostatin A. Angewandte Chemie (International Ed. in English). 40: 3224-3227. PMID 29712036 DOI: 10.1002/1521-3773(20010903)40:17<3224::Aid-Anie3224>3.0.Co;2-D  0.774
2001 Rychnovsky SD, Marumoto S, Jaber JJ. Role of 2-oxonia Cope rearrangements in Prins cyclization reactions. Organic Letters. 3: 3815-8. PMID 11700146 DOI: 10.1021/Ol0168465  0.748
2001 Packard GK, Rychnovsky SD. Beta-selective glycosylations with masked D-mycosamine precursors. Organic Letters. 3: 3393-6. PMID 11594842 DOI: 10.1021/Ol016617I  0.793
2001 Kopecky DJ, Rychnovsky SD. Mukaiyama aldol-Prins cyclization cascade reaction: a formal total synthesis of leucascandrolide A. Journal of the American Chemical Society. 123: 8420-1. PMID 11516301 DOI: 10.1021/Ja011377N  0.746
2001 Jaber JJ, Mitsui K, Rychnovsky SD. Stereoselectivity and regioselectivity in the segment-coupling Prins cyclization. The Journal of Organic Chemistry. 66: 4679-86. PMID 11421792 DOI: 10.1021/Jo010232W  0.769
2001 Rychnovsky SD, Hata T, Kim AI, Buckmelter AJ. Use of a conformational radical clock for evaluating alkyllithium-mediated cyclization reactions. Organic Letters. 3: 807-10. PMID 11263887 DOI: 10.1021/Ol006866R  0.797
2001 Packard GK, Rychnovsky SD. β-Selective glycosylations with masked D-mycosamine precursors Organic Letters. 3: 3393-3396. DOI: 10.1021/ol016617i  0.731
2001 Sinz CJ, Rychnovsky SD. Total synthesis of dermostatin A Angewandte Chemie - International Edition. 40: 3224-3227. DOI: 10.1002/1521-3773(20010903)40:17<3224::AID-ANIE3224>3.0.CO;2-D  0.763
2000 Kopecky DJ, Rychnovsky SD. Improved procedure for the reductive acetylation of acyclic esters and a new synthesis of ethers. The Journal of Organic Chemistry. 65: 191-8. PMID 10813915 DOI: 10.1021/Jo9914521  0.736
2000 Rychnovsky SD, Thomas CR. Synthesis of the C22-C26 tetrahydropyran segment of phorboxazole by a stereoselective prins cyclization Organic Letters. 2: 1217-9. PMID 10810711 DOI: 10.1021/Ol005646A  0.427
2000 Buckmelter AJ, Kim AI, Rychnovsky SD. Conformational memory in enantioselective radical reductions and a new radical clock reaction Journal of the American Chemical Society. 122: 9386-9390. DOI: 10.1021/Ja002068K  0.752
2000 Rychnovsky SD, Bax BM. Enantioselective reduction of esters: Synthesis of optically active α- acetoxy ethers Tetrahedron Letters. 41: 3593-3596. DOI: 10.1016/S0040-4039(00)00470-6  0.816
1999 Rychnovsky SD, Buckmelter AJ, Dahanukar VH, Skalitzky DJ. Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes: Synthons for syn- and anti-1,3-Diols. The Journal of Organic Chemistry. 64: 6849-6860. PMID 11674695 DOI: 10.1021/Jo9909352  0.78
1999 Buckmelter AJ, Powers JP, Rychnovsky SD, Christen DP, Curran DP. Nonequilibrium radical reductions Chemtracts. 12: 635-638. DOI: 10.1021/Ja980857K  0.729
1999 Rychnovsky SD, Fryszman O, Khire UR. Convergent synthesis of a polyol chain with 4-acetoxy-1,3-dioxanes using a 1,1-bis((trimethylsilyl)methyl)ethene linchpin Tetrahedron Letters. 40: 41-44. DOI: 10.1016/S0040-4039(98)80014-2  0.801
1998 Rychnovsky SD, Beauchamp T, Vaidyanathan R, Kwan T. Synthesis of Chiral Nitroxides and an Unusual Racemization Reaction. The Journal of Organic Chemistry. 63: 6363-6374. PMID 11672271 DOI: 10.1021/Jo9808831  0.463
1998 Rychnovsky SD, Sinz CJ. Diastereoselective synthesis of polypropionates: Cationic couplings of 4-acetoxy-1,3-dioxanes with crotyl-metal reagents Tetrahedron Letters. 39: 6811-6814. DOI: 10.1016/S0040-4039(98)01464-6  0.753
1997 Rychnovsky SD, Yang G, Hu Y, Khire UR. Prins Desymmetrization of a C(2)-Symmetric Diol: Application to the Synthesis of 17-Deoxyroflamycoin. The Journal of Organic Chemistry. 62: 3022-3023. PMID 11671673 DOI: 10.1021/Jo970380F  0.366
1997 Evans DA, Barrow JC, Watson PS, Ratz AM, Dinsmore CJ, Evrard DA, DeVries KM, Ellman JA, Rychnovsky SD, Lacour J. Approaches to the synthesis of the vancomycin antibiotics. Synthesis of orienticin C (bis-dechlorovancomycin) aglycon Journal of the American Chemical Society. 119: 3419-3420. DOI: 10.1021/Ja964420T  0.789
1997 Rogers BN, Selsted ME, Rychnovsky SD. Synthesis and biological evaluation of non-polyene analogs of amphotericin B Bioorganic and Medicinal Chemistry Letters. 7: 3177-3182. DOI: 10.1016/S0960-894X(97)10180-9  0.303
1996 Richardson TI, Rychnovsky SD. Filipin III: Configuration Assignment and Confirmation by Synthetic Correlation. The Journal of Organic Chemistry. 61: 4219-4231. PMID 11667319 DOI: 10.1021/Jo960218X  0.349
1995 Beauchamp TJ, Powers JP, Rychnovsky SD. Cascade cyclizations of cyclic sulfates: An enantioselective alternative to polyepoxide cyclizations in the synthesis of poly(tetrahydrofurans) Journal of the American Chemical Society. 117: 12873-12874. DOI: 10.1021/Ja00156A031  0.464
1994 Rychnovsky SD, Hoye RC. Convergent synthesis of the polyene macrolide (-)-roxaticin Journal of the American Chemical Society. 116: 1753-1765. DOI: 10.1021/Ja00084A017  0.489
1993 Poss CS, Rychnovsky SD, Schreiber SL. Two-directional chain synthesis: An application to the synthesis of (+)-mycoticin A Journal of the American Chemical Society. 115: 3360-3361. DOI: 10.1021/Ja00061A057  0.526
1992 Rychnovsky SD, Skalitzky DJ, Pathirana C, Jensen PR, Fenical W. Stereochemistry of the macrolactins Journal of the American Chemical Society. 114: 671-677. DOI: 10.1021/Ja00028A039  0.395
1992 Evans DA, Evrad DA, Rychnovsky SD, Früh T, Whittingham WG, deVries KM. A general approach to the asymmetric synthesis of vancomycin-related arylglycines by enolate azidation Tetrahedron Letters. 33: 1189-1192. DOI: 10.1016/S0040-4039(00)91892-6  0.534
1987 Stork G, Rychnovsky SD. Iterative butenolide construction of polypropionate chains: Application to an efficient synthesis of (+)(9S)-dihydroerythronolide A Pure and Applied Chemistry. 59: 345-352. DOI: 10.1351/Pac198759030345  0.533
1987 Stork G, Rychnovsky SD. Concise total synthesis of (+)-(9S)-dihydroerythronolide A Journal of the American Chemical Society. 109: 1565-1567. DOI: 10.1021/Ja00239A045  0.558
1987 Stork G, Rychnovsky SD. Iterative butenolide construction of polypropionate chains Journal of the American Chemical Society. 109: 1564-1565. DOI: 10.1021/Ja00239A044  0.453
1983 Stork G, Mook R, Biller SA, Rychnovsky SD. Free-radical cyclization of bromoacetals. Use in the construction of bicyclic acetals and lactones Journal of the American Chemical Society. 105: 3741-3742. DOI: 10.1021/Ja00349A082  0.516
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