| Year |
Citation |
Score |
| 2018 |
Tan X, Sun L, Chen J, Chen ZJ. Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids. Annual Review of Microbiology. 72: 447-478. PMID 30200854 DOI: 10.1146/Annurev-Micro-102215-095605 |
0.302 |
|
| 2017 |
Wang H, Hu S, Chen X, Shi H, Chen C, Sun L, Chen ZJ. cGAS is essential for the antitumor effect of immune checkpoint blockade. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137885 DOI: 10.1073/Pnas.1621363114 |
0.307 |
|
| 2016 |
Chen Q, Sun L, Chen ZJ. Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing. Nature Immunology. 17: 1142-1149. PMID 27648547 DOI: 10.1038/Ni.3558 |
0.322 |
|
| 2013 |
Li XD, Wu J, Gao D, Wang H, Sun L, Chen ZJ. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science (New York, N.Y.). 341: 1390-4. PMID 23989956 DOI: 10.1126/Science.1244040 |
0.31 |
|
| 2013 |
Liu S, Chen J, Cai X, Wu J, Chen X, Wu YT, Sun L, Chen ZJ. MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife. 2: e00785. PMID 23951545 DOI: 10.7554/Elife.00785 |
0.36 |
|
| 2013 |
Zhang X, Shi H, Wu J, Zhang X, Sun L, Chen C, Chen ZJ. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Molecular Cell. 51: 226-35. PMID 23747010 DOI: 10.1016/J.Molcel.2013.05.022 |
0.301 |
|
| 2013 |
Sun L, Wu J, Du F, Chen X, Chen ZJ. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway Science. 339: 786-791. PMID 23258413 DOI: 10.1126/Science.1232458 |
0.318 |
|
| 2013 |
Wu J, Sun L, Chen X, Du F, Shi H, Chen C, Chen ZJ. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science (New York, N.Y.). 339: 826-30. PMID 23258412 DOI: 10.1126/Science.1229963 |
0.302 |
|
| 2011 |
Hou F, Sun L, Zheng H, Skaug B, Jiang QX, Chen ZJ. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell. 146: 448-61. PMID 21782231 DOI: 10.1016/J.Cell.2011.06.041 |
0.336 |
|
| 2010 |
Zeng W, Sun L, Jiang X, Chen X, Hou F, Adhikari A, Xu M, Chen ZJ. Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell. 141: 315-30. PMID 20403326 DOI: 10.1016/J.Cell.2010.03.029 |
0.318 |
|
| 2010 |
Sun L, Liu S, Chen ZJ. SnapShot: Pathways of Antiviral Innate Immunity Cell. 140: 436-436.e2. PMID 20144765 DOI: 10.1016/J.Cell.2010.01.041 |
0.319 |
|
| 2009 |
Zeng W, Xu M, Liu S, Sun L, Chen ZJ. Key Role of Ubc5 and Lysine-63 Polyubiquitination in Viral Activation of IRF3 Molecular Cell. 36: 315-325. PMID 19854139 DOI: 10.1016/J.Molcel.2009.09.037 |
0.354 |
|
| 2009 |
Xia ZP, Sun L, Chen X, Pineda G, Jiang X, Adhikari A, Zeng W, Chen ZJ. Direct activation of protein kinases by unanchored polyubiquitin chains. Nature. 461: 114-9. PMID 19675569 DOI: 10.1038/Nature08247 |
0.312 |
|
| 2008 |
Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature. 451: 573-7. PMID 18200010 DOI: 10.1038/Nature06501 |
0.334 |
|
| 2007 |
Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature. 446: 916-920. PMID 17392790 DOI: 10.1038/Nature05732 |
0.34 |
|
| 2006 |
Sun Q, Sun L, Liu HH, Chen X, Seth RB, Forman J, Chen ZJ. The Specific and Essential Role of MAVS in Antiviral Innate Immune Responses Immunity. 24: 633-642. PMID 16713980 DOI: 10.1016/J.Immuni.2006.04.004 |
0.343 |
|
| 2006 |
Seth RB, Sun L, Chen ZJ. Antiviral innate immunity pathways. Cell Research. 16: 141-147. PMID 16474426 DOI: 10.1038/Sj.Cr.7310019 |
0.337 |
|
| 2005 |
Seth RB, Sun L, Ea CK, Chen ZJ. Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3 Cell. 122: 669-682. PMID 16125763 DOI: 10.1016/J.Cell.2005.08.012 |
0.348 |
|
| 2004 |
Ea CK, Sun L, Inoue JI, Chen ZJ. TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6 Proceedings of the National Academy of Sciences of the United States of America. 101: 15318-15323. PMID 15492226 DOI: 10.1073/Pnas.0404132101 |
0.311 |
|
| 2004 |
Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ. The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes Molecular Cell. 14: 289-301. PMID 15125833 DOI: 10.1016/S1097-2765(04)00236-9 |
0.318 |
|
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