Kim David Janda - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Medicinal chemistry
Website:
http://www.scripps.edu/research/chem/faculty.html?name=janda

357 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Staples MC, Herman MA, Lockner JW, Avchalumov Y, Kharidia KM, Janda KD, Roberto M, Mandyam CD. Isoxazole-9 reduces enhanced fear responses and retrieval in ethanol-dependent male rats. Journal of Neuroscience Research. PMID 34496069 DOI: 10.1002/jnr.24932  0.73
2021 Turner LD, Nielsen AL, Lin L, Campedelli AJ, Silvaggi NR, Chen JS, Wakefield AE, Allen KN, Janda KD. Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease. Acs Medicinal Chemistry Letters. 12: 1318-1324. PMID 34413962 DOI: 10.1021/acsmedchemlett.1c00325  0.742
2021 Turner LD, Nielsen AL, Lin L, Pellett S, Sugane T, Olson ME, Johnson EA, Janda KD. Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach. Rsc Medicinal Chemistry. 12: 960-969. PMID 34223161 DOI: 10.1039/d1md00089f  0.749
2021 Shirey RJ, Hart JR, Sridharan B, Novick SJ, Turner LD, Zhou B, Nielsen AL, Eubanks LM, Ueno L, Hixon MS, Lairson LL, Spicer TP, Scampavia LD, Griffin PR, Vogt PK, ... Janda KD, et al. Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay. Bioorganic & Medicinal Chemistry. 42: 116246. PMID 34130216 DOI: 10.1016/j.bmc.2021.116246  0.746
2021 Turner LD, Nielsen AL, Lin L, Pellett S, Sugane T, Olson ME, Janda KD. COVALENT INHIBITION OF BOTULINUM NEUROTOXIN A - EXPLORATION OF WARHEAD REACTIVITY AND FUNCTION USING A BIFUNCTIONAL APPROACH. Toxicon : Official Journal of the International Society On Toxinology. 190: S72-S73. PMID 34103769  0.734
2020 Kyzer JL, McGuire M, Park H, Belz TF, Bonakdar R, Janda KD, Wenthur CJ. Anti-Opioid Antibodies in Individuals Using Chronic Opioid Therapy for Lower Back Pain. Acs Pharmacology & Translational Science. 3: 896-906. PMID 33073189 DOI: 10.1021/acsptsci.0c00057  0.694
2020 Lin L, Olson ME, Sugane T, Turner LD, Tararina MA, Nielsen AL, Kurbanov EK, Pellett S, Johnson EA, Cohen SM, Allen KN, Janda KD. A Catch and Anchor Approach to Combat both Toxicity and Longevity of Botulinum Toxin A. Journal of Medicinal Chemistry. PMID 32886509 DOI: 10.1021/Acs.Jmedchem.0C01006  0.76
2020 Belz TF, Bremer PT, Zhou B, Blake S, Ellis B, Eubanks LM, Janda KD. Sulfonate-isosteric replacement examined within heroin-hapten vaccine design. Bioorganic & Medicinal Chemistry Letters. 30: 127388. PMID 32738981 DOI: 10.1016/J.Bmcl.2020.127388  0.331
2020 Belz TF, Bremer PT, Zhou B, Ellis B, Eubanks LM, Janda KD. Enhancement of a Heroin Vaccine Through Hapten Deuteration. Journal of the American Chemical Society. PMID 32700530 DOI: 10.1021/Jacs.0C05219  0.358
2020 Wang J, Ellis B, Zhou B, Eubanks LM, Blake S, Janda KD. A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope. Chemical Communications (Cambridge, England). PMID 32396160 DOI: 10.1039/D0Cc02107E  0.362
2020 Townsend EA, Bremer P, Faunce K, Negus SS, Jaster A, Robinson H, Janda KD, Banks ML. Evaluation of a dual fentanyl/heroin vaccine on the antinociceptive and reinforcing effects of a fentanyl/heroin mixture in male and female rats. Acs Chemical Neuroscience. PMID 32271538 DOI: 10.1021/Acschemneuro.0C00064  0.329
2020 Lee JC, Kim HY, Lee S, Shin J, Kim HV, Kim K, Baek S, Lee D, Jeon H, Kim D, Yang SH, Han G, Park K, Choi J, Park J, ... ... Janda KD, et al. Discovery of chemicals to clear or indicate amyloid aggregates by targeting memory-impairing anti-parallel Aβ dimers. Angewandte Chemie (International Ed. in English). PMID 32233096 DOI: 10.1002/Anie.202002574  0.649
2020 Natori Y, Janda KD. Synthesis of Drug Vaccine against Heroin Contaminated with Fentanyl and Their Biological Evaluation Journal of Synthetic Organic Chemistry Japan. 78: 875-885. DOI: 10.5059/Yukigoseikyokaishi.78.875  0.327
2019 Olson ME, Sugane T, Zhou B, Janda KD. Consequence of Hapten Stereochemistry: An Efficacious Methamphetamine Vaccine. Journal of the American Chemical Society. 141: 14089-14092. PMID 31479256 DOI: 10.1021/Jacs.9B07294  0.369
2019 Tenney RD, Blake S, Bremer PT, Zhou B, Hwang CS, Poklis JL, Janda KD, Banks ML. Vaccine blunts fentanyl potency in male rhesus monkeys. Neuropharmacology. 107730. PMID 31369740 DOI: 10.1016/J.Neuropharm.2019.107730  0.33
2019 Lin L, Olson ME, Eubanks LM, Janda KD. Strategies to Counteract Botulinum Neurotoxin A: Nature's Deadliest Biomolecule. Accounts of Chemical Research. PMID 31322847 DOI: 10.1021/Acs.Accounts.9B00261  0.316
2019 Smith LC, Bremer PT, Hwang CS, Zhou B, Ellis B, Hixon MS, Janda KD. Monoclonal Antibodies for Combating Synthetic Opioid Intoxication. Journal of the American Chemical Society. PMID 31187995 DOI: 10.1021/Jacs.9B04872  0.314
2019 Hwang CS, Smith LC, Wenthur CJ, Ellis B, Zhou B, Janda KD. Heroin vaccine: Using titer, affinity, and antinociception as metrics when examining sex and strain differences. Vaccine. PMID 31176539 DOI: 10.1016/J.Vaccine.2019.05.061  0.721
2019 Natori Y, Hwang CS, Lin L, Smith LC, Zhou B, Janda KD. A chemically contiguous hapten approach for a heroin-fentanyl vaccine. Beilstein Journal of Organic Chemistry. 15: 1020-1031. PMID 31164940 DOI: 10.3762/Bjoc.15.100  0.363
2019 Wenthur CJ, Gautam R, Zhou B, Vendruscolo LF, Leggio L, Janda KD. Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin. Scientific Reports. 9: 1841. PMID 30755699 DOI: 10.1038/S41598-019-38549-Z  0.785
2019 Lavey BJ, Janda KD. Catalytic Antibody Mediated Hydrolysis of Paraoxon. The Journal of Organic Chemistry. 61: 7633-7636. PMID 11667704 DOI: 10.1021/Jo960629D  0.31
2019 Wenthur CJ, Bonakdar R, Janda KD. Investigation of Immunologic Responses Following Chronic Opioid Use to Treat Lower Back Pain The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.Lb8  0.682
2018 Hwang CS, Ellis B, Zhou B, Janda KD. Heat shock proteins: A dual carrier-adjuvant for an anti-drug vaccine against heroin. Bioorganic & Medicinal Chemistry. PMID 30497790 DOI: 10.1016/J.Bmc.2018.11.027  0.38
2018 Smith LC, Lin L, Hwang CS, Zhou B, Kubitz DM, Wang H, Janda KD. Lateral Flow Assessment and Unanticipated Toxicity of Kratom. Chemical Research in Toxicology. PMID 30380840 DOI: 10.1021/Acs.Chemrestox.8B00218  0.326
2018 Shirey R, Globisch D, Eubanks LM, Hixon MS, Janda KD. Non-Invasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis. Acs Infectious Diseases. PMID 30141624 DOI: 10.1021/Acsinfecdis.8B00163  0.658
2018 Jacob NT, Miranda PO, Shirey RJ, Gautam R, Zhou B, de Orbe Izquierdo ME, Hixon MS, Hart JR, Ueno L, Vogt PK, Janda KD. Synthetic molecules for disruption of the MYC protein-protein interface. Bioorganic & Medicinal Chemistry. PMID 30037753 DOI: 10.1016/J.Bmc.2018.07.019  0.597
2018 Nguyen JD, Hwang CS, Grant Y, Janda KD, Taffe MA. Prophylactic vaccination protects against the development of oxycodone self-administration. Neuropharmacology. PMID 29936242 DOI: 10.1016/J.Neuropharm.2018.06.026  0.337
2018 Kimishima A, Olson ME, Natori Y, Janda KD. Efficient Syntheses of Cocaine Vaccines and Their Evaluation. Acs Medicinal Chemistry Letters. 9: 411-416. PMID 29795751 DOI: 10.1021/Acsmedchemlett.8B00051  0.804
2018 Hwang CS, Smith LC, Natori Y, Ellis B, Zhou B, Janda KD. An efficacious vaccine against heroin contaminated with fentanyl. Acs Chemical Neuroscience. PMID 29558798 DOI: 10.1021/Acschemneuro.8B00079  0.343
2018 Hwang CS, Bremer PT, Wenthur CJ, Ho SO, Chiang S, Ellis B, Zhou B, Fujii G, Janda KD. Enhancing Efficacy and Stability of an Anti-Heroin Vaccine: Examination of Antinociception, Opioid Binding Profile, and Lethality. Molecular Pharmaceutics. PMID 29420901 DOI: 10.1021/Acs.Molpharmaceut.7B00933  0.728
2018 Miranda PO, Cubitt B, Jacob NT, Janda KD, Carlos de la Torre J. Mining a Kröhnke Pyridine Library for Anti-Arenavirus Activity. Acs Infectious Diseases. PMID 29405696 DOI: 10.1021/Acsinfecdis.7B00236  0.336
2018 Ferri GM, Harvey CM, Globisch D, Janda K, Allen KN. Using M. marinum T6PP as a Model for M. tuberculosis Inhibitor Design The Faseb Journal. 32. DOI: 10.1096/Fasebj.2018.32.1_Supplement.674.16  0.627
2017 Kimishima A, Olson ME, Janda KD. Investigations into the efficacy of multi-component cocaine vaccines. Bioorganic & Medicinal Chemistry Letters. PMID 29317163 DOI: 10.1016/J.Bmcl.2017.12.043  0.803
2017 Olson ME, Janda KD. Vaccines to combat the opioid crisis: Vaccines that prevent opioids and other substances of abuse from entering the brain could effectively treat addiction and abuse. Embo Reports. PMID 29237715 DOI: 10.15252/Embr.201745322  0.329
2017 Wenthur CJ, Zhou B, Janda KD. Vaccine-driven pharmacodynamic dissection and mitigation of fenethylline psychoactivity. Nature. PMID 28813419 DOI: 10.1038/Nature23464  0.733
2017 Wenthur CJ, Cai X, Ellis BA, Janda KD. Augmenting the efficacy of anti-cocaine catalytic antibodies through chimeric hapten design and combinatorial vaccination. Bioorganic & Medicinal Chemistry Letters. PMID 28709828 DOI: 10.1016/J.Bmcl.2017.07.014  0.754
2017 Jacob NT, Anraku K, Kimishima A, Zhou B, Collins KC, Lockner JW, Ellis BA, Janda KD. A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior. Chemical Communications (Cambridge, England). PMID 28677711 DOI: 10.1039/C7Cc04055E  0.795
2017 Bremer PT, Janda KD. Conjugate Vaccine Immunotherapy for Substance Use Disorder. Pharmacological Reviews. 69: 298-315. PMID 28634286 DOI: 10.1124/Pr.117.013904  0.377
2017 Globisch D, Eubanks LM, Shirey RJ, Pfarr KM, Wanji S, Debrah AY, Hoerauf A, Janda KD. Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG). Bioorganic & Medicinal Chemistry Letters. PMID 28600214 DOI: 10.1016/J.Bmcl.2017.05.082  0.649
2017 Bremer PT, Schlosburg JE, Banks ML, Steele FF, Zhou B, Poklis JL, Janda KD. Development of a Clinically-Viable Heroin Vaccine. Journal of the American Chemical Society. PMID 28574716 DOI: 10.1021/Jacs.7B03334  0.714
2017 Nguyen JD, Bremer PT, Hwang CS, Vandewater SA, Collins KC, Creehan KM, Janda KD, Taffe MA. Effective active vaccination against methamphetamine in female rats. Drug and Alcohol Dependence. 175: 179-186. PMID 28437722 DOI: 10.1016/J.Drugalcdep.2017.03.005  0.312
2017 Galinato MH, Lockner JW, Fannon-Pavlich MJ, Sobieraj JC, Staples MC, Somkuwar SS, Ghofranian A, Chaing S, Navarro AI, Joea A, Luikart BW, Janda KD, Heyser C, Koob GF, Mandyam CD. A synthetic small-molecule Isoxazole-9 protects against methamphetamine relapse. Molecular Psychiatry. PMID 28348387 DOI: 10.1038/Mp.2017.46  0.777
2017 Anraku K, Sato S, Jacob NT, Eubanks LM, Ellis BA, Janda KD. The design and synthesis of an α-Gal trisaccharide epitope that provides a highly specific anti-Gal immune response. Organic & Biomolecular Chemistry. PMID 28294277 DOI: 10.1039/C7Ob00448F  0.364
2017 Kimishima A, Wenthur CJ, Zhou B, Janda KD. An Advance in Prescription Opioid Vaccines: Overdose Mortality Reduction and Extraordinary Alteration of Drug Half-Life. Acs Chemical Biology. 12: 36-40. PMID 28103678 DOI: 10.1021/Acschembio.6B00977  0.792
2016 Gooyit MD, Miranda PO, Wenthur CJ, Ducime A, Janda KD. Influencing antibody-mediated attenuation of methamphetamine CNS distribution through vaccine linker design. Acs Chemical Neuroscience. PMID 27958709 DOI: 10.1021/Acschemneuro.6B00389  0.806
2016 Nguyen JD, Bremer PT, Ducime A, Creehan KM, Kisby BR, Taffe MA, Janda KD. Active vaccination attenuates the psychostimulant effects of α-PVP and MDPV in rats. Neuropharmacology. PMID 27956054 DOI: 10.1016/J.Neuropharm.2016.12.005  0.325
2016 Kimishima A, Wenthur CJ, Eubanks LM, Sato S, Janda KD. Cocaine Vaccine Development: Evaluation of Carrier and Adjuvant Combinations that Activate Multiple Toll-like Receptors. Molecular Pharmaceutics. PMID 27717287 DOI: 10.1021/Acs.Molpharmaceut.6B00682  0.8
2016 Evans SM, Foltin RW, Hicks MJ, Rosenberg JB, De BP, Janda KD, Kaminsky SM, Crystal RG. Efficacy of an adenovirus-based anti-cocaine vaccine to reduce cocaine self-administration and Reacqusition using a choice procedure in rhesus macaques. Pharmacology, Biochemistry, and Behavior. PMID 27697554 DOI: 10.1016/J.Pbb.2016.09.008  0.353
2016 Gooyit M, Janda KD. Reprofiled anthelmintics abate hypervirulent stationary-phase Clostridium difficile. Scientific Reports. 6: 33642. PMID 27633064 DOI: 10.1038/Srep33642  0.719
2016 Gooyit MD, Janda KD. Modulation of the Surface-Layer Protein of Clostridium difficile through Cwp84 Inhibition. Acs Infectious Diseases. 2: 465-70. PMID 27626098 DOI: 10.1021/Acsinfecdis.6B00061  0.719
2016 Zhou B, Eubanks LM, Jacob NT, Ellis B, Roberts AJ, Janda KD. Studies towards the improvement of an anti-cocaine monoclonal antibody for treatment of acute overdose. Bioorganic & Medicinal Chemistry Letters. PMID 27599743 DOI: 10.1016/J.Bmcl.2016.08.081  0.354
2016 Collins KC, Schlosburg JE, Bremer PT, Janda KD. Methamphetamine Vaccines: Improvement through Hapten Design. Journal of Medicinal Chemistry. PMID 27054372 DOI: 10.1021/Acs.Jmedchem.6B00084  0.7
2016 Jacob NT, Lockner JW, Schlosburg JE, Ellis BA, Eubanks LM, Janda KD. Investigations of Enantiopure Nicotine Haptens using an Adjuvanting Carrier in Anti-Nicotine Vaccine Development. Journal of Medicinal Chemistry. PMID 26918428 DOI: 10.1021/Acs.Jmedchem.5B01676  0.795
2016 Harris TL, Wenthur CJ, Diego-Taboada A, Mackenzie G, Corbitt TS, Janda KD. Lycopodium clavatum exine microcapsules enable safe oral delivery of 3,4-diaminopyridine for treatment of botulinum neurotoxin A intoxication. Chemical Communications (Cambridge, England). PMID 26906286 DOI: 10.1039/C6Cc00615A  0.69
2016 Tsuchikama K, Gooyit M, Harris TL, Zhu J, Globisch D, Kaufmann GF, Janda KD. Glycation Reactivity of a Quorum-Sensing Signaling Molecule. Angewandte Chemie (International Ed. in English). PMID 26890076 DOI: 10.1002/Anie.201511911  0.774
2016 Bremer PT, Kimishima A, Schlosburg JE, Zhou B, Collins KC, Janda KD. Combatting Synthetic Designer Opioids: A Conjugate Vaccine Ablates Lethal Doses of Fentanyl Class Drugs. Angewandte Chemie (International Ed. in English). PMID 26879590 DOI: 10.1002/Anie.201511654  0.797
2016 Hart JR, Weinberg MS, Morris KV, Roberts TC, Janda KD, Garner AL, Vogt PK. MINCR is not a MYC-induced lncRNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 26811502 DOI: 10.1073/Pnas.1519903113  0.565
2015 Gooyit M, Harris TL, Tricoche N, Javor S, Lustigman S, Janda KD. Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping. Acs Infectious Diseases. 1: 198-202. PMID 27622649 DOI: 10.1021/Acsinfecdis.5B00017  0.725
2015 Globisch D, Specht S, Pfarr KM, Eubanks LM, Hoerauf A, Janda KD. Litomosoides sigmodontis: A jird urine metabolome study. Bioorganic & Medicinal Chemistry Letters. 25: 5804-7. PMID 26573416 DOI: 10.1016/J.Bmcl.2015.10.037  0.641
2015 Xue S, Schlosburg JE, Janda KD. A New Strategy for Smoking Cessation: Characterization of a Bacterial Enzyme for the Degradation of Nicotine. Journal of the American Chemical Society. 137: 10136-9. PMID 26237398 DOI: 10.1021/Jacs.5B06605  0.652
2015 Miller ML, Aarde SM, Moreno AY, Creehan KM, Janda KD, Taffe MA. Effects of active anti-methamphetamine vaccination on intravenous self-administration in rats. Drug and Alcohol Dependence. PMID 26118833 DOI: 10.1016/J.Drugalcdep.2015.06.014  0.773
2015 Zhu J, Cai X, Harris TL, Gooyit M, Wood M, Lardy M, Janda KD. Disarming Pseudomonas aeruginosa virulence factor LasB by leveraging a Caenorhabditis elegans infection model. Chemistry & Biology. 22: 483-91. PMID 25892201 DOI: 10.1016/J.Chembiol.2015.03.012  0.727
2015 Gooyit M, Tricoche N, Javor S, Lustigman S, Janda KD. Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting. Acs Medicinal Chemistry Letters. 6: 339-43. PMID 25815157 DOI: 10.1021/Ml500516R  0.723
2015 Lockner JW, Eubanks LM, Choi JL, Lively JM, Schlosburg JE, Collins KC, Globisch D, Rosenfeld-Gunn RJ, Wilson IA, Janda KD. Flagellin as carrier and adjuvant in cocaine vaccine development. Molecular Pharmaceutics. 12: 653-62. PMID 25531528 DOI: 10.1021/Mp500520R  0.807
2015 Lockner JW, Lively JM, Collins KC, Vendruscolo JC, Azar MR, Janda KD. A conjugate vaccine using enantiopure hapten imparts superior nicotine-binding capacity. Journal of Medicinal Chemistry. 58: 1005-11. PMID 25493909 DOI: 10.1021/Jm501625J  0.775
2015 Pippione AC, Dosio F, Ducime A, Federico A, Martina K, Sainas S, Frølund B, Gooyit M, Janda KD, Boschi D, Lolli ML. Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches Medchemcomm. 6: 1285-1292. DOI: 10.1039/C5Md00182J  0.736
2015 Gooyit M, Harris TL, Tricoche N, Javor S, Lustigman S, Janda KD. Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping Acs Infectious Diseases. 1: 198-202. DOI: 10.1021/acsinfecdis.5b00017  0.707
2015 Cai X, Globisch D, Thompson P, Lin J, Toader D, Dimasi N, Gao C, Janda KD. Corrigendum to "A chemoenzymatic approach toward the preparation of site-specific antibody-drug conjugates" [Tetrahedron Lett. 56 (2015) 3172-3175] Tetrahedron Letters. DOI: 10.1016/J.Tetlet.2015.06.088  0.735
2015 Cai X, Janda KD. A chemoenzymatic approach toward the preparation of site-specific antibody-drug conjugates Tetrahedron Letters. 56: 3172-3175. DOI: 10.1016/J.Tetlet.2014.12.025  0.334
2014 Eubanks LM, Ellis BA, Cai X, Schlosburg JE, Janda KD. A human recombinant monoclonal antibody to cocaine: Preparation, characterization and behavioral studies. Bioorganic & Medicinal Chemistry Letters. 24: 4664-6. PMID 25205191 DOI: 10.1016/J.Bmcl.2014.08.035  0.708
2014 Hart JR, Garner AL, Yu J, Ito Y, Sun M, Ueno L, Rhee JK, Baksh MM, Stefan E, Hartl M, Bister K, Vogt PK, Janda KD. Inhibitor of MYC identified in a Kröhnke pyridine library. Proceedings of the National Academy of Sciences of the United States of America. 111: 12556-61. PMID 25114221 DOI: 10.1073/Pnas.1319488111  0.604
2014 Gooyit M, Tricoche N, Lustigman S, Janda KD. Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting. Journal of Medicinal Chemistry. 57: 5792-9. PMID 24918716 DOI: 10.1021/Jm5006435  0.729
2014 Jacob NT, Lockner JW, Kravchenko VV, Janda KD. Pharmacophore reassignment for induction of the immunosurveillance cytokine TRAIL. Angewandte Chemie (International Ed. in English). 53: 6628-31. PMID 24838721 DOI: 10.1002/Anie.201402133  0.747
2014 Hicks MJ, Kaminsky SM, De BP, Rosenberg JB, Evans SM, Foltin RW, Andrenyak DM, Moody DE, Koob GF, Janda KD, Ricart Arbona RJ, Lepherd ML, Crystal RG. Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine. Human Gene Therapy. Clinical Development. 25: 40-9. PMID 24649839 DOI: 10.1089/Humc.2013.231  0.502
2014 Collins KC, Schlosburg JE, Lockner JW, Bremer PT, Ellis BA, Janda KD. Lipid tucaresol as an adjuvant for methamphetamine vaccine development. Chemical Communications (Cambridge, England). 50: 4079-81. PMID 24615284 DOI: 10.1039/C4Cc00682H  0.784
2014 Hicks MJ, Kaminsky SM, De BP, Rosenberg JB, Evans SM, Foltin RW, Andrenyak DM, Moody DE, Koob GF, Janda KD, Ricart Arbona RJ, Lepherd M, Crystal RG. Fate of Systemically Administered Cocaine in Nonhuman Primates Treated with the dAd5GNE Anti-cocaine Vaccine. Human Gene Therapy. Clinical Development. PMID 24548017 DOI: 10.1089/hum.2013.231  0.427
2014 Collins KC, Janda KD. Investigating hapten clustering as a strategy to enhance vaccines against drugs of abuse. Bioconjugate Chemistry. 25: 593-600. PMID 24521489 DOI: 10.1021/Bc500016K  0.355
2014 Bremer PT, Schlosburg JE, Lively JM, Janda KD. Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacy. Molecular Pharmaceutics. 11: 1075-80. PMID 24517171 DOI: 10.1021/Mp400631W  0.708
2014 Miller ML, Moreno A, Aarde S, Creehan K, Janda K, Taffe MA. Active vaccination inhibits the acquisition of methamphetamine self-administration in rats Drug and Alcohol Dependence. 140: e151. DOI: 10.1016/J.Drugalcdep.2014.02.426  0.771
2013 Cai X, Whitfield T, Moreno AY, Grant Y, Hixon MS, Koob GF, Janda KD. Probing the effects of hapten stability on cocaine vaccine immunogenicity. Molecular Pharmaceutics. 10: 4176-84. PMID 23927436 DOI: 10.1021/Mp400214W  0.81
2013 Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Retraction: Stereochemical insignificance discovered in Acinetobacter baumannii quorum sensing (PLoS ONE) Plos One. 8. PMID 23853689 DOI: 10.1371/annotation/8f2ddf91-3499-4627-9a91-449b78465f9d  0.536
2013 Garner AL, Fullagar JL, Day JA, Cohen SM, Janda KD. Development of a high-throughput screen and its use in the discovery of Streptococcus pneumoniae immunoglobulin A1 protease inhibitors. Journal of the American Chemical Society. 135: 10014-7. PMID 23808771 DOI: 10.1021/Ja404180X  0.613
2013 Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Retraction: Stereochemical Insignificance Discovered in Acinetobacter baumannii Quorum Sensing Plos One. 8. PMID 23690906 DOI: 10.1371/Annotation/1345F9B0-016E-4123-9E72-6Ccc4Fa17Ba2  0.602
2013 Zhu J, Hixon MS, Globisch D, Kaufmann GF, Janda KD. Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation. Journal of the American Chemical Society. 135: 7827-30. PMID 23672516 DOI: 10.1021/Ja4024989  0.652
2013 Maoz A, Hicks MJ, Vallabhjosula S, Synan M, Kothari PJ, Dyke JP, Ballon DJ, Kaminsky SM, De BP, Rosenberg JB, Martinez D, Koob GF, Janda KD, Crystal RG. Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2170-8. PMID 23660705 DOI: 10.1038/Npp.2013.114  0.484
2013 Schlosburg JE, Vendruscolo LF, Bremer PT, Lockner JW, Wade CL, Nunes AA, Stowe GN, Edwards S, Janda KD, Koob GF. Dynamic vaccine blocks relapse to compulsive intake of heroin. Proceedings of the National Academy of Sciences of the United States of America. 110: 9036-41. PMID 23650354 DOI: 10.1073/Pnas.1219159110  0.804
2013 Cai X, Whitfield T, Hixon MS, Grant Y, Koob GF, Janda KD. Probing active cocaine vaccination performance through catalytic and noncatalytic hapten design. Journal of Medicinal Chemistry. 56: 3701-9. PMID 23627877 DOI: 10.1021/Jm400228W  0.52
2013 Matyas GR, Mayorov AV, Rice KC, Jacobson AE, Cheng K, Iyer MR, Li F, Beck Z, Janda KD, Alving CR. Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs. Vaccine. 31: 2804-10. PMID 23624097 DOI: 10.1016/J.Vaccine.2013.04.027  0.69
2013 Rosenberg JB, De BP, Hicks MJ, Janda KD, Kaminsky SM, Worgall S, Crystal RG. Suppression of nicotine-induced pathophysiology by an adenovirus hexon-based antinicotine vaccine. Human Gene Therapy. 24: 595-603. PMID 23611296 DOI: 10.1089/Hum.2012.245  0.33
2013 Kravchenko V, Garner AL, Mathison J, Seit-Nebi A, Yu J, Gileva IP, Ulevitch R, Janda KD. Facilitating cytokine-mediated cancer cell death by proteobacterial N-acylhomoserine lactones. Acs Chemical Biology. 8: 1117-20. PMID 23517377 DOI: 10.1021/Cb4000184  0.584
2013 Fullagar JL, Garner AL, Struss AK, Day JA, Martin DP, Yu J, Cai X, Janda KD, Cohen SM. Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase. Chemical Communications (Cambridge, England). 49: 3197-9. PMID 23482955 DOI: 10.1039/C3Cc41191E  0.607
2013 Globisch D, Moreno AY, Hixon MS, Nunes AA, Denery JR, Specht S, Hoerauf A, Janda KD. Onchocerca volvulus-neurotransmitter tyramine is a biomarker for river blindness. Proceedings of the National Academy of Sciences of the United States of America. 110: 4218-23. PMID 23440222 DOI: 10.1073/Pnas.1221969110  0.761
2013 Cai X, Tsuchikama K, Janda KD. Modulating cocaine vaccine potency through hapten fluorination. Journal of the American Chemical Society. 135: 2971-4. PMID 23398531 DOI: 10.1021/Ja400356G  0.373
2013 Struss AK, Nunes A, Waalen J, Lowery CA, Pullanikat P, Denery JR, Conrad DJ, Kaufmann GF, Janda KD. Toward implementation of quorum sensing autoinducers as biomarkers for infectious disease states. Analytical Chemistry. 85: 3355-62. PMID 23391272 DOI: 10.1021/Ac400032A  0.764
2013 Garner AL, Yu J, Struss AK, Kaufmann GF, Kravchenko VV, Janda KD. Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development. Chemical Communications (Cambridge, England). 49: 1515-7. PMID 23328974 DOI: 10.1039/C3Cc38851D  0.605
2013 Lockner JW, Ho SO, McCague KC, Chiang SM, Do TQ, Fujii G, Janda KD. Enhancing nicotine vaccine immunogenicity with liposomes. Bioorganic & Medicinal Chemistry Letters. 23: 975-8. PMID 23313243 DOI: 10.1016/J.Bmcl.2012.12.048  0.776
2013 De BP, Pagovich OE, Hicks MJ, Rosenberg JB, Moreno AY, Janda KD, Koob GF, Worgall S, Kaminsky SM, Sondhi D, Crystal RG. Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity. Human Gene Therapy. 24: 58-66. PMID 23140508 DOI: 10.1089/Hum.2012.163  0.799
2013 Miller ML, Moreno AY, Aarde SM, Creehan KM, Vandewater SA, Vaillancourt BD, Wright MJ, Janda KD, Taffe MA. A methamphetamine vaccine attenuates methamphetamine-induced disruptions in thermoregulation and activity in rats. Biological Psychiatry. 73: 721-8. PMID 23098894 DOI: 10.1016/J.Biopsych.2012.09.010  0.785
2012 Garner AL, Struss AK, Fullagar JL, Agrawal A, Moreno AY, Cohen SM, Janda KD. 3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB. Acs Medicinal Chemistry Letters. 3: 668-672. PMID 23181168 DOI: 10.1021/Ml300128F  0.77
2012 Bremer PT, Janda KD. Investigating the effects of a hydrolytically stable hapten and a Th1 adjuvant on heroin vaccine performance. Journal of Medicinal Chemistry. 55: 10776-80. PMID 23134263 DOI: 10.1021/Jm301262Z  0.321
2012 Moreno AY, Azar MR, Koob GF, Janda KD. Probing the protective effects of a conformationally constrained nicotine vaccine. Vaccine. 30: 6665-70. PMID 22963803 DOI: 10.1016/J.Vaccine.2012.08.064  0.803
2012 Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Stereochemical insignificance discovered in Acinetobacter baumannii quorum sensing. Plos One. 7: e37102. PMID 22629354 DOI: 10.1371/Journal.Pone.0037102  0.61
2012 Rosenberg JB, Hicks MJ, De BP, Pagovich O, Frenk E, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Tignor N, Mezey JG, Crystal RG. AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior. Human Gene Therapy. 23: 451-9. PMID 22486244 DOI: 10.1089/Hum.2011.178  0.497
2012 Treweek JB, Janda KD. An antidote for acute cocaine toxicity. Molecular Pharmaceutics. 9: 969-78. PMID 22380623 DOI: 10.1021/Mp200588V  0.379
2012 Globisch D, Lowery CA, McCague KC, Janda KD. Uncharacterized 4,5-dihydroxy-2,3-pentanedione (DPD) molecules revealed through NMR spectroscopy: implications for a greater signaling diversity in bacterial species. Angewandte Chemie (International Ed. in English). 51: 4204-8. PMID 22378693 DOI: 10.1002/Anie.201109149  0.648
2012 Janda KD, Treweek JB. Vaccines targeting drugs of abuse: is the glass half-empty or half-full? Nature Reviews. Immunology. 12: 67-72. PMID 22173478 DOI: 10.1038/Nri3130  0.335
2012 Zakhari JS, Zorrilla EP, Zhou B, Mayorov AV, Janda KD. Oligoclonal antibody targeting ghrelin increases energy expenditure and reduces food intake in fasted mice. Molecular Pharmaceutics. 9: 281-9. PMID 22149064 DOI: 10.1021/Mp200376C  0.684
2012 Wee S, Hicks MJ, De BP, Rosenberg JB, Moreno AY, Kaminsky SM, Janda KD, Crystal RG, Koob GF. Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1083-91. PMID 21918504 DOI: 10.1038/Npp.2011.200  0.801
2012 Globisch D, Lowery CA, McCague KC, Janda KD. Inside Back Cover: Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species (Angew. Chem. Int. Ed. 17/2012) Angewandte Chemie International Edition. 51: 4239-4239. DOI: 10.1002/Anie.201201407  0.631
2012 Globisch D, Lowery CA, McCague KC, Janda KD. Innenrücktitelbild: Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species (Angew. Chem. 17/2012) Angewandte Chemie. 124: 4313-4313. DOI: 10.1002/Ange.201201407  0.631
2011 Koob G, Hicks MJ, Wee S, Rosenberg JB, De BP, Kaminsky SM, Moreno A, Janda KD, Crystal RG. Anti-cocaine vaccine based on coupling a cocaine analog to a disrupted adenovirus. Cns & Neurological Disorders Drug Targets. 10: 899-904. PMID 22229312 DOI: 10.2174/187152711799219334  0.797
2011 Stowe GN, Schlosburg JE, Vendruscolo LF, Edwards S, Misra KK, Schulteis G, Zakhari JS, Koob GF, Janda KD. Developing a vaccine against multiple psychoactive targets: a case study of heroin. Cns & Neurological Disorders Drug Targets. 10: 865-75. PMID 22229311 DOI: 10.2174/187152711799219316  0.74
2011 Li Z, Garner AL, Gloeckner C, Janda KD, Carlow CK. Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy. Plos Neglected Tropical Diseases. 5: e1411. PMID 22140592 DOI: 10.1371/Journal.Pntd.0001411  0.625
2011 Moreno AY, Janda KD. Current challenges for the creation of effective vaccines against drugs of abuse. Expert Review of Vaccines. 10: 1637-9. PMID 22085165 DOI: 10.1586/Erv.11.145  0.773
2011 Zakhari JS, Kinoyama I, Hixon MS, Di Mola A, Globisch D, Janda KD. Formulating a new basis for the treatment against botulinum neurotoxin intoxication: 3,4-Diaminopyridine prodrug design and characterization. Bioorganic & Medicinal Chemistry. 19: 6203-9. PMID 21975066 DOI: 10.1016/J.Bmc.2011.09.019  0.659
2011 Eubanks LM, Stowe GN, De Lamo Marin S, Mayorov AV, Hixon MS, Janda KD. Identification of α2 macroglobulin as a major serum ghrelin esterase. Angewandte Chemie (International Ed. in English). 50: 10699-702. PMID 21928452 DOI: 10.1002/Anie.201104512  0.647
2011 Garner AL, Park J, Zakhari JS, Lowery CA, Struss AK, Sawada D, Kaufmann GF, Janda KD. A multivalent probe for AI-2 quorum-sensing receptors. Journal of the American Chemical Society. 133: 15934-7. PMID 21913711 DOI: 10.1021/Ja207556D  0.59
2011 Stowe GN, Vendruscolo LF, Edwards S, Schlosburg JE, Misra KK, Schulteis G, Mayorov AV, Zakhari JS, Koob GF, Janda KD. A vaccine strategy that induces protective immunity against heroin. Journal of Medicinal Chemistry. 54: 5195-204. PMID 21692508 DOI: 10.1021/Jm200461M  0.81
2011 Garner AL, Janda KD. A small molecule antagonist of ghrelin O-acyltransferase (GOAT). Chemical Communications (Cambridge, England). 47: 7512-4. PMID 21594284 DOI: 10.1039/C1Cc11817J  0.61
2011 Garner AL, Gloeckner C, Tricoche N, Zakhari JS, Samje M, Cho-Ngwa F, Lustigman S, Janda KD. Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus. Journal of Medicinal Chemistry. 54: 3963-72. PMID 21534605 DOI: 10.1021/Jm200364N  0.623
2011 Uckun FM, Qazi S, Ozer Z, Garner AL, Pitt J, Ma H, Janda KD. Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network. British Journal of Haematology. 153: 741-52. PMID 21517817 DOI: 10.1111/J.1365-2141.2011.08671.X  0.61
2011 Moreno AY, Mayorov AV, Janda KD. Impact of distinct chemical structures for the development of a methamphetamine vaccine. Journal of the American Chemical Society. 133: 6587-95. PMID 21473576 DOI: 10.1021/Ja108807J  0.813
2011 Kirchdoerfer RN, Garner AL, Flack CE, Mee JM, Horswill AR, Janda KD, Kaufmann GF, Wilson IA. Structural basis for ligand recognition and discrimination of a quorum-quenching antibody. The Journal of Biological Chemistry. 286: 17351-8. PMID 21454495 DOI: 10.1074/Jbc.M111.231258  0.634
2011 Šilhár P, Alakurtti S, ?apková K, Xiaochuan F, Shoemaker CB, Yli-Kauhaluoma J, Janda KD. Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease. Bioorganic & Medicinal Chemistry Letters. 21: 2229-31. PMID 21421315 DOI: 10.1016/J.Bmcl.2011.02.115  0.545
2011 Treweek JB, Roberts AJ, Janda KD. Immunopharmacotherapeutic manifolds and modulation of cocaine overdose. Pharmacology, Biochemistry, and Behavior. 98: 474-84. PMID 21356233 DOI: 10.1016/J.Pbb.2011.02.020  0.357
2011 Garner AL, Janda KD. Protein-protein interactions and cancer: targeting the central dogma. Current Topics in Medicinal Chemistry. 11: 258-80. PMID 21320057 DOI: 10.2174/156802611794072614  0.593
2011 Garner AL, Janda KD. Shedding light on the ghrelin/GOAT metabolism saga. Chembiochem : a European Journal of Chemical Biology. 12: 523-5. PMID 21254317 DOI: 10.1002/Cbic.201000777  0.583
2011 Hicks MJ, De BP, Rosenberg JB, Davidson JT, Moreno AY, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Toth M, Mezey JG, Crystal RG. Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 612-9. PMID 21206484 DOI: 10.1038/Mt.2010.280  0.81
2011 Garner AL, Yu J, Struss AK, Lowery CA, Zhu J, Kim SK, Park J, Mayorov AV, Kaufmann GF, Kravchenko VV, Janda KD. Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activation. Bioorganic & Medicinal Chemistry Letters. 21: 2702-5. PMID 21190852 DOI: 10.1016/J.Bmcl.2010.11.122  0.755
2011 Kaufmann GF, Park J, Mayorov AV, Kubitz DM, Janda KD. Generation of quorum quenching antibodies. Methods in Molecular Biology (Clifton, N.J.). 692: 299-311. PMID 21031321 DOI: 10.1007/978-1-60761-971-0_22  0.673
2011 Uckun FM, Qazi S, Garner A, Ma H, Ozer Z, Pitt J, Janda K. Abstract LB-365: Unfolded protein response regulator BIP/HSPA5 as a chemoresistance biomarker and molecular target in acute lymphoblastic leukemia Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-365  0.609
2010 Eubanks LM, Silhár P, Salzameda NT, Zakhari JS, Xiaochuan F, Barbieri JT, Shoemaker CB, Hixon MS, Janda KD. Identification of a Natural Product Antagonist against the Botulinum Neurotoxin Light Chain Protease. Acs Medicinal Chemistry Letters. 1: 268-272. PMID 20959871 DOI: 10.1021/Ml100074S  0.311
2010 Denery JR, Nunes AA, Hixon MS, Dickerson TJ, Janda KD. Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis. Plos Neglected Tropical Diseases. 4. PMID 20957145 DOI: 10.1371/Journal.Pntd.0000834  0.765
2010 Mayorov AV, Willis B, Di Mola A, Adler D, Borgia J, Jackson O, Wang J, Luo Y, Tang L, Knapp RJ, Natarajan C, Goodnough MC, Zilberberg N, Simpson LL, Janda KD. Symptomatic relief of botulinum neurotoxin/a intoxication with aminopyridines: a new twist on an old molecule. Acs Chemical Biology. 5: 1183-91. PMID 20936877 DOI: 10.1021/Cb1002366  0.653
2010 Garner AL, Janda KD. cat-ELCCA: a robust method to monitor the fatty acid acyltransferase activity of ghrelin O-acyltransferase (GOAT). Angewandte Chemie (International Ed. in English). 49: 9630-4. PMID 20845345 DOI: 10.1002/Anie.201003387  0.599
2010 Staflin K, Krueger JS, Hachmann J, Forsyth JS, Lorger M, Steiniger SC, Mee J, Pop C, Salvesen GS, Janda KD, Felding-Habermann B. Targeting activated integrin alphavbeta3 with patient-derived antibodies impacts late-stage multiorgan metastasis. Clinical & Experimental Metastasis. 27: 217-31. PMID 20225083 DOI: 10.1007/S10585-010-9320-5  0.322
2010 Gloeckner C, Garner AL, Mersha F, Oksov Y, Tricoche N, Eubanks LM, Lustigman S, Kaufmann GF, Janda KD. Repositioning of an existing drug for the neglected tropical disease Onchocerciasis. Proceedings of the National Academy of Sciences of the United States of America. 107: 3424-9. PMID 20142509 DOI: 10.1073/Pnas.0915125107  0.627
2010 Moreno AY, Azar MR, Warren NA, Dickerson TJ, Koob GF, Janda KD. A critical evaluation of a nicotine vaccine within a self-administration behavioral model. Molecular Pharmaceutics. 7: 431-41. PMID 20104903 DOI: 10.1021/Mp900213U  0.794
2010 Fukuchi K, Steiniger SC, Deryugina E, Liu Y, Lowery CA, Gloeckner C, Zhou B, Kaufmann GF, Quigley JP, Janda KD. Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Molecular Pharmaceutics. 7: 245-53. PMID 19916495 DOI: 10.1021/Mp900236T  0.302
2010 Han H, Yoon J, Janda KD. ChemInform Abstract: Azatides as Peptidomimetics. Solution and Liquid Phase Syntheses Cheminform. 31: no-no. DOI: 10.1002/CHIN.200030276  0.339
2010 Yoon J, Han H, Janda KD. ChemInform Abstract: Solution and Soluble Polymer Syntheses of Azatides and Aza Peptides Cheminform. 31: no-no. DOI: 10.1002/CHIN.200015248  0.355
2010 Taylor MJ, Yli-Kauhaluoma JT, Ashley JA, Wirsching P, Lerner RA, Janda KD. ChemInform Abstract: The α-Ketoamide Group: A New Motif for the Elicitation of Catalytic Antibodies for Acyl-Transfer Reactions. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199938222  0.49
2010 Taylor MJ, Hoffman TZ, Yli-Kauhaluoma JT, Lerner RA, Janda KD. ChemInform Abstract: A Light-Activated Antibody Catalyst. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199917044  0.477
2010 Yoon J, Cho C, Han H, Janda KD. ChemInform Abstract: Solution and Soluble Polymer Syntheses of 3-Aminoimidazoline-2,4-diones. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199913153  0.346
2010 YLI-KAUHALUOMA JT, HARWIG CW, WENTWORTH PJ, JANDA KD. ChemInform Abstract: Unexpected 1,3-Oxazolidine Formation in the Attempted Oxidation of N-Aryl-N-methyl Substituted β-Amino Alcohols Using Pyridinium Dichromate. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199829101  0.435
2010 YLI-KAUHALUOMA JT, JANDA KD. ChemInform Abstract: An Expedient Synthesis of Isopropyl Anisoles and Veratroles. Cheminform. 25: no-no. DOI: 10.1002/CHIN.199446109  0.45
2009 Frederick MO, De Lamo Marin S, Janda KD, Nicolaou KC, Dickerson TJ. Monoclonal antibodies with orthogonal azaspiracid epitopes. Chembiochem : a European Journal of Chemical Biology. 10: 1625-9. PMID 19492388 DOI: 10.1002/Cbic.200900201  0.621
2009 Moreno AY, Janda KD. Immunopharmacotherapy: vaccination strategies as a treatment for drug abuse and dependence. Pharmacology, Biochemistry, and Behavior. 92: 199-205. PMID 19350728 DOI: 10.1016/J.Pbb.2009.01.015  0.78
2009 Treweek JB, Dickerson TJ, Janda KD. Drugs of abuse that mediate advanced glycation end product formation: a chemical link to disease pathology. Accounts of Chemical Research. 42: 659-69. PMID 19275211 DOI: 10.1021/Ar800247D  0.634
2009 Fischer A, Nakai Y, Eubanks LM, Clancy CM, Tepp WH, Pellett S, Dickerson TJ, Johnson EA, Janda KD, Montal M. Bimodal modulation of the botulinum neurotoxin protein-conducting channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 1330-5. PMID 19164566 DOI: 10.1073/Pnas.0812839106  0.591
2009 Nakai Y, Tepp WH, Dickerson TJ, Johnson EA, Janda KD. Function-oriented synthesis applied to the anti-botulinum natural product toosendanin. Bioorganic & Medicinal Chemistry. 17: 1152-7. PMID 19131252 DOI: 10.1016/J.Bmc.2008.12.042  0.62
2009 Zhou H, Zhou B, Pellett S, Johnson EA, Janda KD. Selection and characterization of a human monoclonal neutralizing antibody for Clostridium Botulinum neurotoxin serotype B. Bioorganic & Medicinal Chemistry Letters. 19: 662-4. PMID 19112017 DOI: 10.1016/J.Bmcl.2008.12.055  0.314
2009 Treweek JB, Moreno AY, Janda KD. SLEEPLESS-ness and insomnia in fruit flies. Angewandte Chemie (International Ed. in English). 48: 438-40. PMID 19072956 DOI: 10.1002/Anie.200804552  0.723
2009 Treweek J, Moreno A, Janda K. Schlaflose Fruchtfliegen durch SLEEPLESS-Verlust Angewandte Chemie. 121: 446-448. DOI: 10.1002/Ange.200804552  0.717
2008 Mayorov AV, Amara N, Chang JY, Moss JA, Hixon MS, Ruiz DI, Meijler MM, Zorrilla EP, Janda KD. Catalytic antibody degradation of ghrelin increases whole-body metabolic rate and reduces refeeding in fasting mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 17487-92. PMID 18981425 DOI: 10.1073/Pnas.0711808105  0.751
2008 Treweek JB, Sun C, Mayorov AV, Qi L, Levy CL, Roberts AJ, Dickerson TJ, Janda KD. Prevention of drug-induced memory impairment by immunopharmacotherapy. Journal of Medicinal Chemistry. 51: 6866-75. PMID 18921991 DOI: 10.1021/Jm800506V  0.777
2008 Willis B, Eubanks LM, Dickerson TJ, Janda KD. The strange case of the botulinum neurotoxin: using chemistry and biology to modulate the most deadly poison. Angewandte Chemie (International Ed. in English). 47: 8360-79. PMID 18844202 DOI: 10.1002/Anie.200705531  0.633
2008 Park J, Dickerson TJ, Janda KD. Major sperm protein as a diagnostic antigen for onchocerciasis. Bioorganic & Medicinal Chemistry. 16: 7206-9. PMID 18632276 DOI: 10.1016/J.Bmc.2008.06.038  0.636
2008 Lowery CA, Dickerson TJ, Janda KD. Interspecies and interkingdom communication mediated by bacterial quorum sensing. Chemical Society Reviews. 37: 1337-46. PMID 18568160 DOI: 10.1039/B702781H  0.579
2008 Kaufmann GF, Park J, Mee JM, Ulevitch RJ, Janda KD. The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone. Molecular Immunology. 45: 2710-4. PMID 18304641 DOI: 10.1016/J.Molimm.2008.01.010  0.309
2008 Zarebski LM, Vaughan K, Sidney J, Peters B, Grey H, Janda KD, Casadevall A, Sette A. Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum. Expert Review of Vaccines. 7: 55-74. PMID 18251694 DOI: 10.1586/14760584.7.1.55  0.327
2008 Willis B, Eubanks LM, Wood MR, Janda KD, Dickerson TJ, Lerner RA. Biologically templated organic polymers with nanoscale order. Proceedings of the National Academy of Sciences of the United States of America. 105: 1416-9. PMID 18216240 DOI: 10.1073/Pnas.0711308105  0.588
2008 Richardson HN, Zhao Y, Fekete EM, Funk CK, Wirsching P, Janda KD, Zorrilla EP, Koob GF. MPZP: a novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist. Pharmacology, Biochemistry, and Behavior. 88: 497-510. PMID 18031798 DOI: 10.1016/j.pbb.2007.10.008  0.329
2008 Zhou B, Carney C, Janda KD. Selection and characterization of human antibodies neutralizing Bacillus anthracis toxin. Bioorganic & Medicinal Chemistry. 16: 1903-13. PMID 18023190 DOI: 10.1016/J.Bmc.2007.11.001  0.355
2008 Brogan AP, Dickerson TJ, Janda KD. ChemInform Abstract: Nornicotine-Organocatalyzed Aqueous Reduction of α,β-Unsaturated Aldehydes. Cheminform. 39. DOI: 10.1002/chin.200812079  0.524
2008 Willis B, Eubanks L, Dickerson T, Janda K. Der seltsame Fall des Botulinum-Neurotoxins: chemische und biologische Modulierung des tödlichsten aller Gifte Angewandte Chemie. 120: 8488-8507. DOI: 10.1002/Ange.200705531  0.562
2007 Brogan AP, Dickerson TJ, Janda KD. Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes. Chemical Communications (Cambridge, England). 4952-4. PMID 18361380 DOI: 10.1039/B713273E  0.574
2007 Park J, Jagasia R, Kaufmann GF, Mathison JC, Ruiz DI, Moss JA, Meijler MM, Ulevitch RJ, Janda KD. Infection control by antibody disruption of bacterial quorum sensing signaling. Chemistry & Biology. 14: 1119-27. PMID 17961824 DOI: 10.1016/J.Chembiol.2007.08.013  0.603
2007 Capková K, Yoneda Y, Dickerson TJ, Janda KD. Synthesis and structure-activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 6463-6. PMID 17951059 DOI: 10.1016/J.Bmcl.2007.09.103  0.596
2007 Zhou H, Zhou B, Ma H, Carney C, Janda KD. Selection and characterization of human monoclonal antibodies against Abrin by phage display. Bioorganic & Medicinal Chemistry Letters. 17: 5690-2. PMID 17764932 DOI: 10.1016/J.Bmcl.2007.07.053  0.307
2007 Dickerson TJ, McKenzie KM, Hoyt AS, Wood MR, Janda KD, Brenner SB, Lerner RA. Phage escape libraries for checkmate analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12703-8. PMID 17646645 DOI: 10.1073/Pnas.0705362104  0.612
2007 Treweek J, Wee S, Koob GF, Dickerson TJ, Janda KD. Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 11580-4. PMID 17592122 DOI: 10.1073/Pnas.0701328104  0.696
2007 Ino A, Dickerson TJ, Janda KD. Positional linker effects in haptens for cocaine immunopharmacotherapy. Bioorganic & Medicinal Chemistry Letters. 17: 4280-3. PMID 17531484 DOI: 10.1016/J.Bmcl.2007.05.032  0.648
2007 Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA. Crystal structures of a quorum-quenching antibody. Journal of Molecular Biology. 368: 1392-402. PMID 17400249 DOI: 10.1016/J.Jmb.2007.02.081  0.314
2007 Liu Y, Steiniger SC, Kim Y, Kaufmann GF, Felding-Habermann B, Janda KD. Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery. Molecular Pharmaceutics. 4: 435-47. PMID 17373820 DOI: 10.1021/Mp060122J  0.465
2007 Xu Y, Hixon MS, Yamamoto N, McAllister LA, Wentworth AD, Wentworth P, Janda KD. Antibody-catalyzed anaerobic destruction of methamphetamine. Proceedings of the National Academy of Sciences of the United States of America. 104: 3681-6. PMID 17360412 DOI: 10.1073/Pnas.0611094104  0.334
2007 Brogan AP, Eubanks LM, Koob GF, Dickerson TJ, Janda KD. Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol. Journal of the American Chemical Society. 129: 3698-702. PMID 17335216 DOI: 10.1021/Ja070022M  0.677
2007 Eubanks LM, Dickerson TJ, Janda KD. Technological advancements for the detection of and protection against biological and chemical warfare agents. Chemical Society Reviews. 36: 458-70. PMID 17325785 DOI: 10.1039/B615227A  0.592
2007 McAllister LA, Hixon MS, Schwartz R, Kubitz DS, Janda KD. Synthesis and application of a novel ligand for affinity chromatography based removal of endotoxin from antibodies. Bioconjugate Chemistry. 18: 559-66. PMID 17315943 DOI: 10.1021/Bc0602984  0.303
2007 Eubanks LM, Hixon MS, Jin W, Hong S, Clancy CM, Tepp WH, Baldwin MR, Malizio CJ, Goodnough MC, Barbieri JT, Johnson EA, Boger DL, Dickerson TJ, Janda KD. An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists. Proceedings of the National Academy of Sciences of the United States of America. 104: 2602-7. PMID 17293454 DOI: 10.1073/Pnas.0611213104  0.623
2007 De Lamo Marin S, Xu Y, Meijler MM, Janda KD. Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria. Bioorganic & Medicinal Chemistry Letters. 17: 1549-52. PMID 17254784 DOI: 10.1016/J.Bmcl.2006.12.118  0.319
2007 Steiniger SC, Altobell LJ, Zhou B, Janda KD. Selection of human antibodies against cell surface-associated oligomeric anthrax protective antigen. Molecular Immunology. 44: 2749-55. PMID 17210180 DOI: 10.1016/J.Molimm.2006.11.011  0.343
2007 McKenzie KM, Mee JM, Rogers CJ, Hixon MS, Kaufmann GF, Janda KD. Identification and characterization of single chain anti-cocaine catalytic antibodies. Journal of Molecular Biology. 365: 722-31. PMID 17084858 DOI: 10.1016/J.Jmb.2006.10.031  0.351
2006 Dickerson TJ, Janda KD. The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication. Acs Chemical Biology. 1: 359-69. PMID 17163773 DOI: 10.1021/Cb600179D  0.617
2006 Eubanks LM, Rogers CJ, Beuscher AE, Koob GF, Olson AJ, Dickerson TJ, Janda KD. A molecular link between the active component of marijuana and Alzheimer's disease pathology. Molecular Pharmaceutics. 3: 773-7. PMID 17140265 DOI: 10.1021/Mp060066M  0.645
2006 Rogers CJ, Eubanks LM, Dickerson TJ, Janda KD. Unexpected acetylcholinesterase activity of cocaine esterases. Journal of the American Chemical Society. 128: 15364-5. PMID 17131989 DOI: 10.1021/JA066241+  0.626
2006 Brogan AP, Dickerson TJ, Janda KD. Enamine-based aldol organocatalysis in water: are they really "all wet"? Angewandte Chemie (International Ed. in English). 45: 8100-2. PMID 17001595 DOI: 10.1002/Anie.200601392  0.561
2006 Zorrilla EP, Iwasaki S, Moss JA, Chang J, Otsuji J, Inoue K, Meijler MM, Janda KD. Vaccination against weight gain. Proceedings of the National Academy of Sciences of the United States of America. 103: 13226-31. PMID 16891413 DOI: 10.1073/Pnas.0605376103  0.619
2006 Kim Y, Lillo AM, Steiniger SC, Liu Y, Ballatore C, Anichini A, Mortarini R, Kaufmann GF, Zhou B, Felding-Habermann B, Janda KD. Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand. Biochemistry. 45: 9434-44. PMID 16878978 DOI: 10.1021/Bi060264J  0.454
2006 Xu Y, Lu H, Kennedy JP, Yan X, McAllister LA, Yamamoto N, Moss JA, Boldt GE, Jiang S, Janda KD. Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation. Journal of Combinatorial Chemistry. 8: 531-9. PMID 16827565 DOI: 10.1021/Cc0600167  0.588
2006 Boldt GE, Kennedy JP, Hixon MS, McAllister LA, Barbieri JT, Tzipori S, Janda KD. Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin a inhibitors. Journal of Combinatorial Chemistry. 8: 513-21. PMID 16827563 DOI: 10.1021/Cc060010H  0.304
2006 Ma H, Zhou B, Kim Y, Janda KD. A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A. Toxicon : Official Journal of the International Society On Toxinology. 47: 901-8. PMID 16730044 DOI: 10.1016/J.Toxicon.2006.03.003  0.454
2006 Moss JA, Stokols S, Hixon MS, Ashley FT, Chang JY, Janda KD. Solid-phase synthesis and kinetic characterization of fluorogenic enzyme-degradable hydrogel cross-linkers. Biomacromolecules. 7: 1011-6. PMID 16602715 DOI: 10.1021/Bm051001S  0.596
2006 McAllister LA, Hixon MS, Kennedy JP, Dickerson TJ, Janda KD. Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: a new wrinkle in botulinum neurotoxin. Journal of the American Chemical Society. 128: 4176-7. PMID 16568962 DOI: 10.1021/Ja057699Z  0.614
2006 Boldt GE, Dickerson TJ, Janda KD. Emerging chemical and biological approaches for the preparation of discovery libraries. Drug Discovery Today. 11: 143-8. PMID 16533712 DOI: 10.1016/S1359-6446(05)03697-4  0.617
2006 Kaufmann GF, Sartorio R, Lee SH, Mee JM, Altobell LJ, Kujawa DP, Jeffries E, Clapham B, Meijler MM, Janda KD. Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing. Journal of the American Chemical Society. 128: 2802-3. PMID 16506750 DOI: 10.1021/Ja0578698  0.304
2006 Zhu X, Dickerson TJ, Rogers CJ, Kaufmann GF, Mee JM, McKenzie KM, Janda KD, Wilson IA. Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure (London, England : 1993). 14: 205-16. PMID 16472740 DOI: 10.1016/J.Str.2005.10.014  0.641
2006 Xu Y, Shi J, Yamamoto N, Moss JA, Vogt PK, Janda KD. A credit-card library approach for disrupting protein-protein interactions. Bioorganic & Medicinal Chemistry. 14: 2660-73. PMID 16384710 DOI: 10.1016/J.Bmc.2005.11.052  0.581
2006 Shigenaga A, Moss JA, Ashley FT, Kaufmann GF, Janda KD. Solid-phase synthesis and cyclative cleavage of quorum sensing depsipeptide analogues by acylphenyldiazene activation Synlett. 551-554. DOI: 10.1055/S-2006-932468  0.604
2006 Rogers CJ, Dickerson TJ, Janda KD. Kinetic isotope and thermodynamic analysis of the nornicotine-catalyzed aqueous aldol reaction Tetrahedron. 62: 352-356. DOI: 10.1016/J.Tet.2005.09.094  0.599
2005 Dickerson TJ, Janda KD. Retraction note to: Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy Aaps Journal. 14: 542-542. PMID 22585345 DOI: 10.1208/S12248-012-9365-2  0.635
2005 Dickerson TJ, Janda KD. Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy. The Aaps Journal. 7: E579-86. PMID 16353936 DOI: 10.1208/aapsj070359  0.635
2005 Kim Y, Lillo A, Moss JA, Janda KD. A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide. Molecular Pharmaceutics. 2: 528-35. PMID 16323960 DOI: 10.1021/Mp050035B  0.636
2005 Shute TS, Matsushita M, Dickerson TJ, La Clair JJ, Janda KD, Burkart MD. A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjugate Chemistry. 16: 1352-5. PMID 16287229 DOI: 10.1021/Bc050213J  0.611
2005 Qi L, Yamamoto N, Meijler MM, Altobell LJ, Koob GF, Wirsching P, Janda KD. Delta9-tetrahydrocannabinol immunochemical studies: haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 48: 7389-99. PMID 16279798 DOI: 10.1021/Jm050442R  0.498
2005 Toker JD, Tremblay MR, Yli-Kauhaluoma J, Wentworth AD, Zhou B, Wentworth P, Janda KD. Exploring the scope of the 29G12 antibody catalyzed 1,3-dipolar cycloaddition reaction. The Journal of Organic Chemistry. 70: 7810-5. PMID 16277300 DOI: 10.1021/Jo050410B  0.763
2005 Dickerson TJ, Beuscher AE, Rogers CJ, Hixon MS, Yamamoto N, Xu Y, Olson AJ, Janda KD. Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library. Biochemistry. 44: 14845-53. PMID 16274232 DOI: 10.1021/Bi051613X  0.603
2005 Eubanks LM, Dickerson TJ, Janda KD. Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A. Febs Letters. 579: 5361-4. PMID 16198354 DOI: 10.1016/J.Febslet.2005.08.072  0.602
2005 Xu Y, Yamamoto N, Ruiz DI, Kubitz DS, Janda KD. Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies Bioorganic and Medicinal Chemistry Letters. 15: 4304-4307. PMID 16046128 DOI: 10.1016/J.Bmcl.2005.06.052  0.322
2005 Brogan AP, Dickerson TJ, Boldt GE, Janda KD. Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development. Proceedings of the National Academy of Sciences of the United States of America. 102: 10433-8. PMID 16014706 DOI: 10.1073/Pnas.0504721102  0.592
2005 Rogers CJ, Mee JM, Kaufmann GF, Dickerson TJ, Janda KD. Toward cocaine esterase therapeutics. Journal of the American Chemical Society. 127: 10016-7. PMID 16011362 DOI: 10.1021/Ja053086A  0.629
2005 Carrera MR, Trigo JM, Wirsching P, Roberts AJ, Janda KD. Evaluation of the anticocaine monoclonal antibody GNC92H2 as an immunotherapy for cocaine overdose. Pharmacology, Biochemistry, and Behavior. 81: 709-14. PMID 16005948 DOI: 10.1016/J.Pbb.2005.04.018  0.794
2005 Dickerson TJ, Kaufmann GF, Janda KD. Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy. Expert Opinion On Biological Therapy. 5: 773-81. PMID 15952908 DOI: 10.1517/14712598.5.6.773  0.638
2005 Rogers CJ, Dickerson TJ, Brogan AP, Janda KD. Hammett correlation of nornicotine analogues in the aqueous aldol reaction: implications for green organocatalysis. The Journal of Organic Chemistry. 70: 3705-8. PMID 15845010 DOI: 10.1021/Jo050161R  0.596
2005 Reed NN, Dickerson TJ, Boldt GE, Janda KD. Enantioreversal in the sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer. The Journal of Organic Chemistry. 70: 1728-31. PMID 15730294 DOI: 10.1021/Jo048009X  0.6
2005 Meijler MM, Kaufmann GF, Qi L, Mee JM, Coyle AR, Moss JA, Wirsching P, Matsushita M, Janda KD. Fluorescent cocaine probes: a tool for the selection and engineering of therapeutic antibodies. Journal of the American Chemical Society. 127: 2477-84. PMID 15725002 DOI: 10.1021/Ja043935E  0.635
2005 Moss JA, Lillo A, Kim YS, Gao C, Ditzel H, Janda KD. A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide. Journal of the American Chemical Society. 127: 538-9. PMID 15643874 DOI: 10.1021/Ja0443171  0.66
2005 Kaufmann GF, Sartorio R, Lee SH, Rogers CJ, Meijler MM, Moss JA, Clapham B, Brogan AP, Dickerson TJ, Janda KD. Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones. Proceedings of the National Academy of Sciences of the United States of America. 102: 309-14. PMID 15623555 DOI: 10.1073/Pnas.0408639102  0.717
2005 Xu Y, Yamamoto N, Janda KD. Catalytic antibodies: hapten design strategies and screening methods. Bioorganic & Medicinal Chemistry. 12: 5247-68. PMID 15388154 DOI: 10.1016/J.Bmc.2004.03.077  0.329
2005 Rogers CJ, Dickerson TJ, Wentworth P, Janda KD. A high-swelling reagent scaffold suitable for use in aqueous and organic solvents Tetrahedron. 61: 12140-12144. DOI: 10.1055/S-2006-931979  0.585
2005 Reed NN, Dickerson TJ, oldt GEB, Janda KD. Molecular Weight Induced Enantioreversal in Sharpless Asymmetric Epoxidation Synfacts. 2005: 44-44. DOI: 10.1055/S-2005-869913  0.574
2004 Meijler MM, Matsushita M, Wirsching P, Janda KD. Development of immunopharmacotherapy against drugs of abuse. Current Drug Discovery Technologies. 1: 77-89. PMID 16472221 DOI: 10.2174/1570163043484851  0.337
2004 Dickerson TJ, Reed NN, LaClair JJ, Janda KD. A precipitator for the detection of thiophilic metals in aqua. Journal of the American Chemical Society. 126: 16582-6. PMID 15600364 DOI: 10.1021/Ja045798R  0.587
2004 Felding-Habermann B, Lerner RA, Lillo A, Zhuang S, Weber MR, Arrues S, Gao C, Mao S, Saven A, Janda KD. Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. 101: 17210-5. PMID 15563590 DOI: 10.1073/Pnas.0407869101  0.545
2004 Kim YS, Moss JA, Janda KD. Biological tuning of synthetic tactics in solid-phase synthesis: application to A beta(1-42). The Journal of Organic Chemistry. 69: 7776-8. PMID 15498016 DOI: 10.1021/Jo048922Y  0.576
2004 Dickerson TJ, Lovell T, Meijler MM, Noodleman L, Janda KD. Nornicotine aqueous aldol reactions: synthetic and theoretical investigations into the origins of catalysis. The Journal of Organic Chemistry. 69: 6603-9. PMID 15387581 DOI: 10.1021/Jo048894J  0.612
2004 Dickerson TJ, Yamamoto N, Ruiz DI, Janda KD. Immunological consequences of methamphetamine protein glycation. Journal of the American Chemical Society. 126: 11446-7. PMID 15366884 DOI: 10.1021/Ja047690H  0.642
2004 Carrera MR, Meijler MM, Janda KD. Cocaine pharmacology and current pharmacotherapies for its abuse. Bioorganic & Medicinal Chemistry. 12: 5019-30. PMID 15351386 DOI: 10.1016/J.Bmc.2004.06.018  0.799
2004 Dickerson TJ, Yamamoto N, Janda KD. Antibody-catalyzed oxidative degradation of nicotine using riboflavin. Bioorganic & Medicinal Chemistry. 12: 4981-7. PMID 15336277 DOI: 10.1016/J.Bmc.2004.07.006  0.626
2004 Lillo AM, Sun C, Gao C, Ditzel H, Parrish J, Gauss CM, Moss J, Felding-Habermann B, Wirsching P, Boger DL, Janda KD. A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents. Chemistry & Biology. 11: 897-906. PMID 15271348 DOI: 10.1016/J.Chembiol.2004.04.018  0.698
2004 Carrera MR, Kaufmann GF, Mee JM, Meijler MM, Koob GF, Janda KD. Treating cocaine addiction with viruses. Proceedings of the National Academy of Sciences of the United States of America. 101: 10416-21. PMID 15226496 DOI: 10.1073/Pnas.0403795101  0.794
2004 Meijler MM, Hom LG, Kaufmann GF, McKenzie KM, Sun C, Moss JA, Matsushita M, Janda KD. Synthesis and biological validation of a ubiquitous quorum-sensing molecule. Angewandte Chemie (International Ed. in English). 43: 2106-8. PMID 15083457 DOI: 10.1002/Anie.200353150  0.571
2004 Ahn JM, Wentworth P, Janda KD. Probing lipase/esterase libraries for lipid A hydrolases--discovery of biocatalysts for the detoxification of bacterially-expressed recombinant protein. Chemical Communications (Cambridge, England). 364-5. PMID 14765210 DOI: 10.1039/B312662E  0.525
2004 Carrera MR, Ashley JA, Hoffman TZ, Isomura S, Wirsching P, Koob GF, Janda KD. Investigations using immunization to attenuate the psychoactive effects of nicotine. Bioorganic & Medicinal Chemistry. 12: 563-70. PMID 14738965 DOI: 10.1016/J.Bmc.2003.11.029  0.787
2004 Kim YS, Moss JA, Janda KD. P1-175 Development of conformation-specific antibodies for neutralization of β-amyloid oligomers Neurobiology of Aging. 25: S145. DOI: 10.1016/S0197-4580(04)80488-3  0.586
2003 Dickerson TJ, Tremblay MR, Hoffman TZ, Ruiz DI, Janda KD. Catalysis of the photo-Fries reaction: antibody-mediated stabilization of high energy states. Journal of the American Chemical Society. 125: 15395-401. PMID 14664584 DOI: 10.1021/Ja038016N  0.638
2003 Moss JA, Coyle AR, Ahn JM, Meijler MM, Offer J, Janda KD. Tandem IMAC-HPLC purification of a cocaine-binding scFv antibody. Journal of Immunological Methods. 281: 143-8. PMID 14580888 DOI: 10.1016/J.Jim.2003.07.010  0.706
2003 Dickerson TJ, Janda KD. Glycation of the amyloid beta-protein by a nicotine metabolite: a fortuitous chemical dynamic between smoking and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 8182-7. PMID 12815102 DOI: 10.1073/Pnas.1332847100  0.597
2003 Meijler MM, Matsushita M, Altobell LJ, Wirsching P, Janda KD. A new strategy for improved nicotine vaccines using conformationally constrained haptens. Journal of the American Chemical Society. 125: 7164-5. PMID 12797775 DOI: 10.1021/Ja034805T  0.324
2003 Zhu X, Heine A, Monnat F, Houk KN, Janda KD, Wilson IA. Structural basis for antibody catalysis of a cationic cyclization reaction. Journal of Molecular Biology. 329: 69-83. PMID 12742019 DOI: 10.1016/S0022-2836(03)00406-6  0.307
2003 Gambs C, Dickerson TJ, Mahajan S, Pasternack LB, Janda KD. High-resolution diffusion-ordered spectroscopy to probe the microenvironment of JandaJel and Merrifield resins. The Journal of Organic Chemistry. 68: 3673-8. PMID 12713377 DOI: 10.1021/Jo034152Z  0.594
2003 Redwan el-RM, Larsen NA, Zhou B, Wirsching P, Janda KD, Wilson IA. Expression and characterization of a humanized cocaine-binding antibody. Biotechnology and Bioengineering. 82: 612-8. PMID 12652485 DOI: 10.1002/Bit.10598  0.35
2003 Ahn JM, Wentworth P, Janda KD. Soluble polymer-supported convergent parallel library synthesis. Chemical Communications (Cambridge, England). 480-1. PMID 12638959 DOI: 10.1039/B210696E  0.518
2003 Gao C, Mao S, Ronca F, Zhuang S, Quaranta V, Wirsching P, Janda KD. De novo identification of tumor-specific internalizing human antibody-receptor pairs by phage-display methods. Journal of Immunological Methods. 274: 185-97. PMID 12609544 DOI: 10.1016/S0022-1759(02)00522-7  0.501
2003 Cannizzaro CE, Ashley JA, Janda KD, Houk KN. Experimental determination of the absolute enantioselectivity of an antibody-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity. Journal of the American Chemical Society. 125: 2489-506. PMID 12603137 DOI: 10.1021/Ja020879D  0.304
2003 Wentworth P, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens. Proceedings of the National Academy of Sciences of the United States of America. 100: 1490-3. PMID 12576548 DOI: 10.1073/Pnas.0437831100  0.308
2003 Isomura S, Ashley JA, Wirsching P, Janda KD. Antibody-catalyzed cleavage of the D-Ala-D-Lac depsipeptide: an immunological approach to the problem of vancomycin resistance. Bioorganic & Medicinal Chemistry Letters. 12: 861-4. PMID 11958980 DOI: 10.1016/S0960-894X(02)00047-1  0.302
2002 Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science (New York, N.Y.). 298: 2195-9. PMID 12434011 DOI: 10.1126/Science.1077642  0.313
2002 Gao C, Mao S, Ditzel HJ, Farnaes L, Wirsching P, Lerner RA, Janda KD. A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library. Bioorganic & Medicinal Chemistry. 10: 4057-65. PMID 12413859 DOI: 10.1016/S0968-0896(02)00340-1  0.492
2002 Dickerson TJ, Janda KD. A previously undescribed chemical link between smoking and metabolic disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 15084-8. PMID 12403823 DOI: 10.1073/Pnas.222561699  0.609
2002 Lee KJ, Mao S, Sun C, Gao C, Blixt O, Arrues S, Hom LG, Kaufmann GF, Hoffman TZ, Coyle AR, Paulson J, Felding-Habermann B, Janda KD. Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen. Journal of the American Chemical Society. 124: 12439-46. PMID 12381184 DOI: 10.1021/Ja020737J  0.505
2002 Dickerson TJ, Reed NN, Janda KD. Soluble polymers as scaffolds for recoverable catalysts and reagents. Chemical Reviews. 102: 3325-44. PMID 12371887 DOI: 10.1021/Cr010335E  0.581
2002 Ahn JM, Boyle NA, MacDonald MT, Janda KD. Peptidomimetics and peptide backbone modifications. Mini Reviews in Medicinal Chemistry. 2: 463-73. PMID 12370047 DOI: 10.2174/1389557023405828  0.492
2002 Gao C, Mao S, Kaufmann G, Wirsching P, Lerner RA, Janda KD. A method for the generation of combinatorial antibody libraries using pIX phage display. Proceedings of the National Academy of Sciences of the United States of America. 99: 12612-6. PMID 12239343 DOI: 10.1073/Pnas.192467999  0.79
2002 Sun C, Wirsching P, Janda KD. Syntheses of dendritic linkers containing chlorambucil residues for the preparation of antibody-multidrug immunoconjugates. Bioorganic & Medicinal Chemistry Letters. 12: 2213-5. PMID 12127540 DOI: 10.1016/S0960-894X(02)00361-X  0.337
2002 Delgado M, Lee KJ, Altobell L, Spanka C, Wentworth P, Janda KD. A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity. Journal of the American Chemical Society. 124: 4946-7. PMID 11982344 DOI: 10.1021/Ja025715B  0.331
2002 Zhou B, Wirsching P, Janda KD. Human antibodies against spores of the genus Bacillus: a model study for detection of and protection against anthrax and the bioterrorist threat. Proceedings of the National Academy of Sciences of the United States of America. 99: 5241-6. PMID 11959974 DOI: 10.1073/Pnas.082121599  0.304
2002 Isomura S, Hoffman TZ, Wirsching P, Janda KD. Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration. Journal of the American Chemical Society. 124: 3661-8. PMID 11929256 DOI: 10.1021/Ja012376Y  0.34
2002 Dickerson TJ, Janda KD. Aqueous aldol catalysis by a nicotine metabolite. Journal of the American Chemical Society. 124: 3220-1. PMID 11916401 DOI: 10.1021/Ja017774F  0.602
2002 Wentworth P, Janda KD. Catalytic antibodies: structure and function. Cell Biochemistry and Biophysics. 35: 63-87. PMID 11898856 DOI: 10.1385/Cbb:35:1:63  0.31
2002 Kim GT, Wenz M, Park JI, Hasserodt J, Janda KD. Polyene substrates with unusual methylation patterns to probe the active sites of three catalytic antibodies. Bioorganic & Medicinal Chemistry. 10: 1249-62. PMID 11886788 DOI: 10.1016/S0968-0896(01)00402-3  0.334
2002 Moss JA, Dickerson TJ, Janda KD. Solid phase peptide synthesis on JandaJel™ resin Tetrahedron Letters. 43: 37-40. DOI: 10.1016/S0040-4039(01)02076-7  0.712
2001 Kozlov IA, Mao S, Xu Y, Huang X, Lee L, Sears PS, Gao C, Coyle AR, Janda KD, Wong CH. Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates. Chembiochem : a European Journal of Chemical Biology. 2: 741-6. PMID 11948856 DOI: 10.1002/1439-7633(20011001)2:10<741::Aid-Cbic741>3.0.Co;2-B  0.506
2001 Córdova A, Janda KD. Synthesis and catalytic antibody functionalization of dendrimers Journal of the American Chemical Society. 123: 8248-8259. PMID 11516276 DOI: 10.1021/Ja001819F  0.558
2001 Córdova A, Tremblay MR, Clapham B, Janda KD. A sequential application of kinetic resolution and polymer-supported scavenging for the isolation of chiral secondary alcohols. The Journal of Organic Chemistry. 66: 5645-8. PMID 11485501 DOI: 10.1021/Jo010529U  0.478
2001 Jones LH, Harwig CW, Wentworth P, Simeonov A, Wentworth AD, Py S, Ashley JA, Lerner RA, Janda KD. Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: implications for an alternative enediyne therapeutic mechanism. Journal of the American Chemical Society. 123: 3607-8. PMID 11472138 DOI: 10.1021/Ja005864Z  0.312
2001 Larsen NA, Zhou B, Heine A, Wirsching P, Janda KD, Wilson IA. Crystal structure of a cocaine-binding antibody. Journal of Molecular Biology. 311: 9-15. PMID 11469854 DOI: 10.1006/Jmbi.2001.4839  0.331
2001 Dickerson TJ, Reed NN, Janda KD. Regio-reactive resin: a platform for orthogonal loading using the polymer backbone and cross-linker. Bioorganic & Medicinal Chemistry Letters. 11: 1507-9. PMID 11412970 DOI: 10.1016/S0960-894X(01)00152-4  0.604
2001 Córdova A, Janda KD. A highly chemo- and stereoselective synthesis of β-keto esters via a polymer-supported lipase catalyzed transesterfication Journal of Organic Chemistry. 66: 1906-1909. PMID 11262145 DOI: 10.1021/Jo001478O  0.488
2001 Chen DW, Beuscher AE, Stevens RC, Wirsching P, Lerner RA, Janda KD. Preparation of stilbene-tethered nonnatural nucleosides for use with blue-fluorescent antibodies. The Journal of Organic Chemistry. 66: 1725-32. PMID 11262119 DOI: 10.1021/Jo001676F  0.317
2001 Matsushita M, Hoffman TZ, Ashley JA, Zhou B, Wirsching P, Janda KD. Cocaine catalytic antibodies: the primary importance of linker effects. Bioorganic & Medicinal Chemistry Letters. 11: 87-90. PMID 11206477 DOI: 10.1016/S0960-894X(00)00659-4  0.356
2001 Carrera MR, Ashley JA, Wirsching P, Koob GF, Janda KD. A second-generation vaccine protects against the psychoactive effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. 98: 1988-92. PMID 11172063 DOI: 10.1073/Pnas.98.4.1988  0.798
2001 Toy PH, Reger TS, Garibay P, Garno JC, Malikayil JA, Liu GY, Janda KD. Polytetrahydrofuran cross-linked polystyrene resins for solid-phase organic synthesis Journal of Combinatorial Chemistry. 3: 117-124. PMID 11148072 DOI: 10.1021/Cc000083F  0.584
2001 Chen D, Kubiak RJ, Ashley JA, Janda KD. Reactive immunization elicits catalytic antibodies for polyester hydrolysis Journal of the Chemical Society-Perkin Transactions 1. 2796-2803. DOI: 10.1039/B105412K  0.319
2001 Tremblay M, Dickerson T, Janda K. Advances in Antibody Catalysis of Cycloaddition Reactions Advanced Synthesis & Catalysis. 343: 577-585. DOI: 10.1002/1615-4169(200108)343:6/7<577::Aid-Adsc577>3.0.Co;2-Z  0.613
2001 Tremblay MR, Dickerson TJ, Janda KD. Advances in Antibody Catalysis of Cycloaddition Reactions Advanced Synthesis and Catalysis. 343: 577-585.  0.582
2000 Simeonov A, Matsushita M, Juban EA, Thompson EH, Hoffman TZ, Beuscher AE, Taylor MJ, Wirsching P, Rettig W, McCusker JK, Stevens RC, Millar DP, Schultz PG, Lerner RA, Janda KD. Blue-fluorescent antibodies. Science (New York, N.Y.). 290: 307-13. PMID 11030644 DOI: 10.1126/Science.290.5490.307  0.312
2000 Wentworth AD, Jones LH, Wentworth P, Janda KD, Lerner RA. Antibodies have the intrinsic capacity to destroy antigens. Proceedings of the National Academy of Sciences of the United States of America. 97: 10930-5. PMID 11005865 DOI: 10.1073/Pnas.97.20.10930  0.33
2000 Toy PH, Janda KD. Soluble polymer-supported organic synthesis Accounts of Chemical Research. 33: 546-554. PMID 10955985 DOI: 10.1021/Ar990140H  0.573
2000 Toy PH, Reger TS, Janda KD. Soluble polymer bound cleavage reagents: a multipolymer strategy for the cleavage of tertiary amines from REM resin. Organic Letters. 2: 2205-7. PMID 10930244 DOI: 10.1021/Ol0059403  0.583
2000 Hasserodt J, Janda KD, Lerner RA. A class of 4-aza-lithocholic acid-derived haptens for the generation of catalytic antibodies with steroid synthase capabilities. Bioorganic & Medicinal Chemistry. 8: 995-1003. PMID 10882011 DOI: 10.1016/S0968-0896(00)00036-5  0.305
2000 Harwig CW, Hoffman TZ, Wentworth AD, Janda KD. A one-pot multistep approach to alpha-azido-phosphonate and phosphonothioate diesters: key intermediates in the synthesis of haptens for the generation of antibody ligases. Bioorganic & Medicinal Chemistry Letters. 10: 915-8. PMID 10853659 DOI: 10.1016/S0960-894X(00)00137-2  0.303
2000 Carrera MR, Ashley JA, Zhou B, Wirsching P, Koob GF, Janda KD. Cocaine vaccines: antibody protection against relapse in a rat model. Proceedings of the National Academy of Sciences of the United States of America. 97: 6202-6. PMID 10823960 DOI: 10.1073/Pnas.97.11.6202  0.802
2000 Toker JD, Wentworth P, Hu Y, Houk KN, Janda KD. Antibody-catalysis of a bimolecular asymmetric 1,3-dipolar cycloaddition reaction [15] Journal of the American Chemical Society. 122: 3244-3245. DOI: 10.1021/Ja994423G  0.781
2000 Hasserodt J, Janda KD, Lerner RA. Antibodies mimic natural oxidosqualene-cyclase action in steroid ring a formation Journal of the American Chemical Society. 122: 40-45. DOI: 10.1021/Ja993054L  0.315
2000 Toy PH, Janda KD. ChemInform Abstract: Soluble Polymer-Supported Organic Synthesis Cheminform. 31: no-no. DOI: 10.1002/CHIN.200044261  0.52
1999 Sieber F, Wentworth P, Toker JD, Wentworth AD, Metz WA, Reed NN, Janda KD. Development and Application of a Poly(ethylene glycol)-Supported Triarylphosphine Reagent:  Expanding the Sphere of Liquid-Phase Organic Synthesis. The Journal of Organic Chemistry. 64: 5188-5192. PMID 34237880 DOI: 10.1021/jo9903712  0.776
1999 Córdova A, Reed NN, Ashley JA, Janda KD. Convenient synthesis of L-proline benzyl ester. Bioorganic & Medicinal Chemistry Letters. 9: 3119-22. PMID 10560736 DOI: 10.1016/S0960-894X(99)00546-6  0.496
1999 Spivak DA, Hoffman TZ, Moore AH, Taylor MJ, Janda KD. A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis. Bioorganic & Medicinal Chemistry. 7: 1145-50. PMID 10428386 DOI: 10.1016/S0968-0896(99)00026-7  0.305
1999 Mao S, Gao C, Lo CH, Wirsching P, Wong CH, Janda KD. Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewisx and Lewisx. Proceedings of the National Academy of Sciences of the United States of America. 96: 6953-8. PMID 10359820 DOI: 10.1073/Pnas.96.12.6953  0.546
1999 Gao C, Mao S, Lo CH, Wirsching P, Lerner RA, Janda KD. Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays. Proceedings of the National Academy of Sciences of the United States of America. 96: 6025-30. PMID 10339535 DOI: 10.1073/Pnas.96.11.6025  0.534
1999 Janda KD, Wentworth AD. A Merging of Chemistry and Biology in Terms of Antibody Catalysis Phosphorus, Sulfur, and Silicon and the Related Elements. 144: 117-120. DOI: 10.1080/10426509908546196  0.314
1999 Wentworth P, Janda KD. Antibody catalysis of phosphodiester hydrolysis a survey of hapten strategies Phosphorus Sulfur and Silicon and the Related Elements. 144: 247-250. DOI: 10.1080/10426509908039543  0.325
1999 Garibay P, Toy PH, Hoeg-Jensen T, Janda KD. Application of a New Solid-Phase Resin: Benzamide ortho-Lithiation and the Synthesis of a Phthalide Library Synlett. 1999: 1438-1440. DOI: 10.1055/S-1999-2863  0.574
1999 Taylor MJ, Yli-Kauhaluoma JT, Ashley JA, Wirsching P, Lerner RA, Janda KD. The α-ketoamide group: A new motif for the elicitation of catalytic antibodies for acyl-transfer reactions Journal of the Chemical Society - Perkin Transactions 1. 1133-1134. DOI: 10.1039/A902475A  0.554
1999 Sieber F, Wentworth P, Toker JD, Wentworth AD, Metz WA, Reed NN, Janda KD. Development and application of a poly(ethylene glycol)-supported triarylphosphine reagent: Expanding the sphere of liquid-phase organic synthesis Journal of Organic Chemistry. 64: 5188-5192. DOI: 10.1021/Jo9903712  0.774
1999 Datta A, Wentworth, P, Shaw JP, Simeonov A, Janda KD. Catalytically Distinct Antibodies Prepared by the Reactive Immunization versus Transition State Analogue Hapten Manifolds Journal of the American Chemical Society. 121: 10461-10467. DOI: 10.1021/Ja991274T  0.301
1999 Gao C, Brümmer O, Mao S, Janda KD. Selection of Human Metalloantibodies from a Combinatorial Phage Single-Chain Antibody Library Journal of the American Chemical Society. 121: 6517-6518. DOI: 10.1021/Ja990966E  0.52
1999 Toy PH, Janda KD. New supports for solid-phase organic synthesis: Development of polystyrene resins containing tetrahydrofuran derived cross-linkers Tetrahedron Letters. 40: 6329-6332. DOI: 10.1016/S0040-4039(99)01251-4  0.578
1999 Brümmer O, Gao C, Mao S, Weiner DP, Janda KD. Design, synthesis and characterization of panning agents for the selection of metalloantibodies Letters in Peptide Science. 6: 295-302. DOI: 10.1007/Bf02443425  0.504
1998 Wentworth P, Liu Y, Wentworth AD, Fan P, Foley MJ, Janda KD. A bait and switch hapten strategy generates catalytic antibodies for phosphodiester hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 95: 5971-5. PMID 9600901 DOI: 10.1073/Pnas.95.11.5971  0.322
1998 Heine A, Stura EA, Yli-Kauhaluoma JT, Gao C, Deng Q, Beno BR, Houk KN, Janda KD, Wilson IA. An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution. Science (New York, N.Y.). 279: 1934-40. PMID 9506943 DOI: 10.1126/Science.279.5358.1934  0.673
1998 Yoon J, Cho CW, Han H, Janda KD. Solution and soluble polymer syntheses of 3-aminoimidazoline-2,4-diones Chemical Communications. 2703-2704. DOI: 10.1039/A807067I  0.443
1998 Han H, Yoon J, Janda KD. An Efficient Asymmetric Route to 2,3-Diaminobutanoic Acids The Journal of Organic Chemistry. 63: 2045-2048. DOI: 10.1021/Jo9720391  0.46
1998 Taylor MJ, Hoffman TZ, Yli-Kauhaluoma JT, Lerner RA, Janda KD. A light-activated antibody catalyst Journal of the American Chemical Society. 120: 12783-12790. DOI: 10.1021/Ja982711R  0.568
1998 Gao C, Lavey BJ, Lo CL, Datta A, Wentworth P, Janda KD. Direct Selection for Catalysis from Combinatorial Antibody Libraries Using a Boronic Acid Probe:  Primary Amide Bond Hydrolysis Journal of the American Chemical Society. 120: 2211-2217. DOI: 10.1021/Ja9720220  0.535
1998 Yli-Kauhaluoma JT, Harwig CW, Wentworth P, Janda KD. Unexpected 1,3-oxazolidine formation in the attempted oxidation of N-aryl-N-methyl substituted β-amino alcohols using pyridinium dichromate Tetrahedron Letters. 39: 2269-2272. DOI: 10.1016/S0040-4039(98)00289-5  0.5
1997 Gao C, Lin CH, Lo CH, Mao S, Wirsching P, Lerner RA, Janda KD. Making chemistry selectable by linking it to infectivity. Proceedings of the National Academy of Sciences of the United States of America. 94: 11777-82. PMID 9342313 DOI: 10.1073/Pnas.94.22.11777  0.536
1997 Lin CH, Hoffman TZ, Wirsching P, Barbas CF, Janda KD, Lerner RA. On roads not taken in the evolution of protein catalysts: antibody steroid isomerases that use an enamine mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 11773-6. PMID 9342312 DOI: 10.1073/Pnas.94.22.11773  0.32
1997 Janda KD, Lo LC, Lo CH, Sim MM, Wang R, Wong CH, Lerner RA. Chemical selection for catalysis in combinatorial antibody libraries. Science (New York, N.Y.). 275: 945-8. PMID 9020070 DOI: 10.1126/Science.275.5302.945  0.311
1997 Lo CL, Wentworth P, Jung KW, Yoon J, Ashley JA, Janda KD. Reactive Immunization Strategy Generates Antibodies with High Catalytic Proficiencies Journal of the American Chemical Society. 119: 10251-10252. DOI: 10.1021/Ja971442M  0.501
1997 Hasserodt J, Janda KD, Lerner RA. Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization Journal of the American Chemical Society. 119: 5993-5998. DOI: 10.1021/Ja970675A  0.313
1997 Li T, Lerner RA, Janda KD. Antibody-Catalyzed Cationic Reactions: Rerouting of Chemical Transformations via Antibody Catalysis Accounts of Chemical Research. 30: 115-121. DOI: 10.1021/Ar960172U  0.303
1997 Hasserodt J, Janda KD. Syntheses of octahydroquinoline-N-oxides: Haptens designed to elicit catalytic antibodies that control a terpenoid-like cascade cyclisation Tetrahedron. 53: 11237-11256. DOI: 10.1016/S0040-4020(97)00715-1  0.305
1996 Hasserodt J, Janda KD, Lerner RA. Antibody catalyzed terpenoid cyclization Journal of the American Chemical Society. 118: 11654-11655. DOI: 10.1021/Ja954316W  0.31
1996 Yli-Kauhaluoma JT, Ashley JA, Lo CL, Coakley J, Wirsching P, Janda KD. Catalytic Antibodies with Peptidyl−Prolyl Cis−Trans Isomerase Activity Journal of the American Chemical Society. 118: 5496-5497. DOI: 10.1021/Ja954206P  0.556
1996 Sakurai M, Wirsching P, Janda KD. Design and synthesis of a cocaine-diamide hapten for vaccine development Tetrahedron Letters. 37: 5479-5482. DOI: 10.1016/0040-4039(96)01170-7  0.342
1996 Lo CHL, Gao C, Mao S, Matsui K, Lerner RA, Janda KD. Chain shuffling: Investigations into the specificity and selectivity of antibody catalysis Israel Journal of Chemistry. 36: 195-198. DOI: 10.1002/Ijch.199600026  0.549
1995 Han H, Wolfe MM, Brenner S, Janda KD. Liquid-phase combinatorial synthesis Proceedings of the National Academy of Sciences of the United States of America. 92: 6419-6423. PMID 7541541 DOI: 10.1073/Pnas.92.14.6419  0.314
1995 Carrera MR, Ashley JA, Parsons LH, Wirsching P, Koob GF, Janda KD. Suppression of psychoactive effects of cocaine by active immunization. Nature. 378: 727-30. PMID 7501020 DOI: 10.1038/378727A0  0.79
1995 Yli-Kauhaluoma JT, Ashley JA, Lo C, Tucker L, Wolfe MM, Janda KD. Anti-Metallocene Antibodies: A New Approach to Enantioselective Catalysis of the Diels-Alder Reaction Journal of the American Chemical Society. 117: 7041-7047. DOI: 10.1021/Ja00132A001  0.561
1995 Janda KD, Shevlin CG, Lerner RA. Oxepane synthesis along a disfavored pathway: The rerouting of a chemical reaction using a catalytic antibody Journal of the American Chemical Society. 117: 2659-2660. DOI: 10.1021/Ja00114A035  0.309
1995 Li T, Hilton S, Janda KD. The Potential Application of Catalytic Antibodies to Protecting Group Removal: Catalytic Antibodies with Broad Substrate Tolerance Journal of the American Chemical Society. 117: 2123-2127. DOI: 10.1021/Ja00113A001  0.314
1995 Rosenblum JS, Lo LC, Li T, Janda KD, Lerner RA. Antibody-catalyzed phosphate triester hydrolysis Angewandte Chemie (International Edition in English). 34: 2275-2277. DOI: 10.1002/Anie.199522751  0.301
1994 Li T, Janda KD, Ashley JA, Lerner RA. Antibody catalyzed cationic cyclization Science. 264: 1289-1293. PMID 8191282 DOI: 10.1126/Science.8191282  0.308
1994 Janda KD, Lo CHL, Li T, Barbas CF, Wirsching P, Lerner RA. Direct selection for a catalytic mechanism from combinatorial antibody libraries Proceedings of the National Academy of Sciences of the United States of America. 91: 2532-2536. PMID 8146149 DOI: 10.1073/Pnas.91.7.2532  0.308
1994 Yli-Kauhaluoma J, Janda KD. Twisted α-keto amides as transition-state analogues for acyl-transfer reactions: Synthesis of the immunoconjugates Bioorganic and Medicinal Chemistry. 2: 521-528. PMID 7528089 DOI: 10.1016/0968-0896(94)80022-7  0.566
1994 Janda KD. Catalytic antibodies and enzyme inhibitors Pure and Applied Chemistry. 66: 703-708. DOI: 10.1351/Pac199466040703  0.323
1994 Shevlin CG, Hilton S, Janda KD. Automation of antibody catalysis: a practical methodology for the use of catalytic antibodies in organic synthesis Bioorganic & Medicinal Chemistry Letters. 4: 297-302. DOI: 10.1016/S0960-894X(01)80132-3  0.322
1994 Yli-Kauhaluoma JT, Janda KD. An expedient synthesis of isopropyl anisoles and veratroles Tetrahedron Letters. 35: 4509-4510. DOI: 10.1016/S0040-4039(00)60713-X  0.519
1994 Nielsen J, Janda KD. Toward Chemical Implementation of Encoded Combinatorial Libraries Methods. 6: 361-371. DOI: 10.1006/Meth.1994.1036  0.545
1993 Janda KD, Shevlin CG, Lerner RA. Antibody catalysis of a disfavored chemical transformation Science. 259: 490-493. PMID 8424171 DOI: 10.1126/Science.8424171  0.31
1993 IKEDA S, Janda KD. Recent Development on the Research of Catalytic Antibodies and Their Applications. Journal of Synthetic Organic Chemistry, Japan. 51: 284-297. DOI: 10.5059/Yukigoseikyokaishi.51.284  0.319
1993 Nielsen J, Brenner S, Janda KD. Synthetic methods for the implementation of encoded combinatorial chemistry Journal of the American Chemical Society. 115: 9812-9813. DOI: 10.1021/Ja00074A063  0.511
1993 Na J, Houk KN, Shevlin CG, Janda KD, Lerner RA. The energetic advantage of 5-exo versus 6-endo epoxide openings: a preference overwhelmed by antibody catalysis Journal of the American Chemical Society. 115: 8453-8454. DOI: 10.1021/Ja00071A067  0.305
1993 Jack Chen YC, Danon T, Sastry L, Mubaraki M, Janda KD, Lerner RA. Catalytic antibodies from combinatorial libraries Journal of the American Chemical Society. 115: 357-358. DOI: 10.1021/Ja00054A058  0.309
1992 Hein MB, Tang Y, McLeod DA, Janda KD, Hiatt A. Evaluation of immunoglobulins from plant cells. Biotechnology Progress. 7: 455-61. PMID 1367994 DOI: 10.1021/Bp00011A011  0.301
1992 Fernholz E, Schloeder D, Liu KKC, Bradshaw CW, Huang H, Janda K, Lerner RA, Wong CH. Specificity of antibody-catalyzed transesterifications using enol esters: A comparison with lipase reactions Journal of Organic Chemistry. 57: 4756-4761. DOI: 10.1021/Jo00043A042  0.304
1992 Gibbs RA, Benkovic PA, Janda KD, Lerner RA, Benkovic SJ. Substituent effects of an antibody-catalyzed hydrolysis of phenyl esters: further evidence for an acyl-antibody intermediate Journal of the American Chemical Society. 114: 3528-3534. DOI: 10.1021/Ja00035A057  0.304
1992 Reymond JL, Janda KD, Lerner RA. Highly enantioselective protonation catalyzed by an antibody Journal of the American Chemical Society. 114: 2257-2258. DOI: 10.1021/Ja00032A050  0.301
1991 Wirsching P, Ashley JA, Benkovic SJ, Janda KD, Lerner RA. An unexpectedly efficient catalytic antibody operating by ping-pong and induced fit mechanisms. Science (New York, N.Y.). 252: 680-5. PMID 2024120 DOI: 10.1126/Science.2024120  0.334
1991 Kang AS, Barbas CF, Janda KD, Benkovic SJ, Lerner RA. Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. Proceedings of the National Academy of Sciences of the United States of America. 88: 4363-6. PMID 1903540 DOI: 10.1073/Pnas.88.10.4363  0.305
1991 Ikeda S, Weinhouse MI, Janda KD, Lerner RA, Danishefsky SJ. Asymmetric induction via a catalytic antibody Journal of the American Chemical Society. 113: 7763-7764. DOI: 10.1021/Ja00020A049  0.307
1991 Janda KD, Benkovic SJ, McLeod DA, Schloeder DM, Lerner RA. Substrate attenuation: An approach to improve antibody catalysis Tetrahedron. 47: 2503-2506. DOI: 10.1016/S0040-4020(01)81784-1  0.318
1990 Benkovic SJ, Adams JA, Borders CL, Janda KD, Lerner RA. The enzymic nature of antibody catalysis: development of multistep kinetic processing. Science (New York, N.Y.). 250: 1135-9. PMID 2251500 DOI: 10.1126/Science.2251500  0.322
1990 Janda KD. New strategies for the design of catalytic antibodies Biotechnology Progress. 6: 178-181. PMID 1366610 DOI: 10.1021/Bp00003A002  0.31
1989 Sastry L, Alting-Mees M, Huse WD, Short JM, Sorge JA, Hay BN, Janda KD, Benkovic SJ, Lerner RA. Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library. Proceedings of the National Academy of Sciences of the United States of America. 86: 5728-32. PMID 2503822 DOI: 10.1073/Pnas.86.15.5728  0.323
1988 Janda KD, Schloeder D, Benkovic SJ, Lerner RA. Induction of an antibody that catalyzes the hydrolysis of an amide bond. Science (New York, N.Y.). 241: 1188-91. PMID 3413482 DOI: 10.1126/Science.3413482  0.304
1986 Tramontano A, Janda KD, Lerner RA. Chemical reactivity at an antibody binding site elicited by mechanistic design of a synthetic antigen. Proceedings of the National Academy of Sciences of the United States of America. 83: 6736-40. PMID 3462723 DOI: 10.1073/Pnas.83.18.6736  0.344
1985 Bates RB, Janda KD, Wright ME. N-Isobutyrylbenzamide, C11H13NO2 Acta Crystallographica Section C Crystal Structure Communications. 41: 263-264. DOI: 10.1107/S0108270185003559  0.446
1985 BATES RB, FLETCHER FA, JANDA KD, MILLER WA. ChemInform Abstract: A CONVENIENT SYNTHESIS OF UNSYMMETRICAL ACYCLIC IMIDES Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198502163  0.412
1984 Bates RB, Janda KD. A Convenient Synthesis of α-Acylamino Alcohols from Azlactones Synthesis. 1984: 310-311. DOI: 10.1055/S-1984-30820  0.457
1984 Bates RB, Fletcher FA, Janda KD, Miller WA. A convenient synthesis of unsymmetrical acyclic imides The Journal of Organic Chemistry. 49: 3038-3038. DOI: 10.1002/Chin.198502163  0.481
1984 BATES RB, GIN SL, HASSEN MA, HRUBY VJ, JANDA KD, KRIEK GR, MICHAUD J, VINE DB. ChemInform Abstract: SYNTHESIS OF CYCLO-N-METHYL-L-TYR-N-METHYL-L-TYR-D-ALA-L-ALA-O,N-DIMETHYL-L-TYR-L-ALA, A CYCLIC HEXAPEPTIDE RELATED TO THE ANTITUMOR AGENT DEOXYBOUVARDIN Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198440222  0.539
1984 BATES RB, JANDA KD. ChemInform Abstract: A CONVENIENT SYNTHESIS OF α-ACYLAMINO ALCOHOLS FROM AZLACTONES Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198436151  0.39
1983 BATES RB, JANDA KD. ChemInform Abstract: HIGH-YIELD BENZYNE SYNTHESIS OF DIARYL ETHERS Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198311133  0.414
1982 Bates RB, Janda KD. High-yield benzyne synthesis of diaryl ethers The Journal of Organic Chemistry. 47: 4374-4376. DOI: 10.1021/Jo00143A051  0.482
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