John A. Katzenellenbogen - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
steroid hormones
Website:
http://chemistry.illinois.edu/faculty/John_Katzenellenbogen.html

265 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Madak-Erdogan Z, Band S, Zhao YC, Smith BP, Kulkoyluoglu-Cotul E, Zuo Q, Santaliz Casiano A, Wrobel K, Rossi G, Smith RL, Kim SH, Katzenellenbogen JA, Johnson ML, Patel M, Marino N, et al. Free fatty acids rewire cancer metabolism in obesity-associated breast cancer via estrogen receptor and mTOR signaling. Cancer Research. PMID 30862719 DOI: 10.1158/0008-5472.CAN-18-2849  0.48
2019 Karim H, Kim SH, Lauderdale K, Lapato AS, Atkinson K, Yasui N, Yamate-Morgan H, Sekyi M, Katzenellenbogen JA, Tiwari-Woodruff SK. Analogues of ERβ ligand chloroindazole exert immunomodulatory and remyelinating effects in a mouse model of multiple sclerosis. Scientific Reports. 9: 503. PMID 30679747 DOI: 10.1038/s41598-018-37420-x  0.48
2018 Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, ... ... Katzenellenbogen JA, et al. The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife. 7. PMID 30489256 DOI: 10.7554/eLife.37161  1
2018 Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. Acs Chemical Biology. PMID 30404440 DOI: 10.1021/acschembio.8b00877  1
2018 Selvaraj UM, Zuurbier K, Whoolery C, Plautz EJ, Chambliss KL, Kong X, Zhang S, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Mineo C, Shaul PW, Stowe AM. Selective Non-nuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice. Endocrinology. PMID 30256928 DOI: 10.1210/en.2018-00600  0.48
2018 Zhou D, Xu J, Mpoy C, Chu W, Kim SH, Li H, Rogers BE, Katzenellenbogen JA. Preliminary evaluation of a novel F-labeled PARP-1 ligand for PET imaging of PARP-1 expression in prostate cancer. Nuclear Medicine and Biology. 66: 26-31. PMID 30195072 DOI: 10.1016/j.nucmedbio.2018.08.003  0.48
2018 Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 30185950 DOI: 10.1038/s41568-018-0053-0  0.92
2018 Bononi G, Granchi C, Lapillo M, Giannotti M, Nieri D, Fortunato S, Boustani ME, Caligiuri I, Poli G, Carlson KE, Kim SH, Macchia M, Martinelli A, Rizzolio F, Chicca A, ... Katzenellenbogen JA, et al. Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors. European Journal of Medicinal Chemistry. 157: 817-836. PMID 30144699 DOI: 10.1016/j.ejmech.2018.08.038  1
2018 Wang L, Guillen VS, Sharma N, Flessa K, Min J, Carlson KE, Toy W, Braqi S, Katzenellenbogen BS, Katzenellenbogen JA, Chandarlapaty S, Sharma A. New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons. Acs Medicinal Chemistry Letters. 9: 803-808. PMID 30128071 DOI: 10.1021/acsmedchemlett.8b00106  1
2018 Pollock JA, Sharma N, Ippagunta SK, Redecke V, Häcker H, Katzenellenbogen J. Triaryl Pyrazole Toll-Like Receptor Signaling Inhibitors: Structure-Activity Relationships Governing Pan- and Selective Signaling Inhibitors. Chemmedchem. PMID 30117269 DOI: 10.1002/cmdc.201800417  0.48
2018 Ippagunta SK, Pollock JA, Sharma N, Lin W, Chen T, Tawaratsumida K, High AA, Min J, Chen Y, Guy RK, Redecke V, Katzenellenbogen JA, Häcker H. Identification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins. Science Signaling. 11. PMID 30108181 DOI: 10.1126/scisignal.aaq1077  0.48
2018 Guivarc'h E, Buscato M, Guihot AL, Favre J, Vessières E, Grimaud L, Wakim J, Melhem NJ, Zahreddine R, Adlanmerini M, Loufrani L, Knauf C, Katzenellenbogen JA, Katzenellenbogen BS, Foidart JM, et al. Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety. Journal of the American Heart Association. 7. PMID 29959137 DOI: 10.1161/JAHA.118.008950  0.44
2018 Karim H, Kim SH, Lapato AS, Yasui N, Katzenellenbogen JA, Tiwari-Woodruff SK. Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination. Proceedings of the National Academy of Sciences of the United States of America. PMID 29844175 DOI: 10.1073/pnas.1721732115  0.48
2018 Chen KLA, Liu X, Zhao YC, Hieronymi K, Rossi G, Auvil LS, Welge M, Bushell C, Smith RL, Carlson KE, Kim SH, Katzenellenbogen JA, Miller MJ, Madak-Erdogan Z. Long-Term Administration of Conjugated Estrogen and Bazedoxifene Decreased Murine Fecal β-Glucuronidase Activity Without Impacting Overall Microbiome Community. Scientific Reports. 8: 8166. PMID 29802368 DOI: 10.1038/s41598-018-26506-1  1
2018 Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 29662238 DOI: 10.1038/s41568-018-0001-z  0.92
2018 Vinel A, Coudert AE, Buscato M, Valera MC, Agnès O, Katzenellenbogen JA, Katzenellenbogen BS, Berdal A, Babajko S, Arnal JF, Fontaine C. Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: implications for ERα modulation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29624728 DOI: 10.1002/jbmr.3434  0.44
2018 Miranda CL, Johnson LA, de Montgolfier O, Elias VD, Ullrich LS, Hay JJ, Paraiso IL, Choi J, Reed RL, Revel JS, Kioussi C, Bobe G, Iwaniec UT, Turner RT, Katzenellenbogen BS, ... Katzenellenbogen JA, et al. Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice. Scientific Reports. 8: 613. PMID 29330372 DOI: 10.1038/s41598-017-18992-6  0.44
2017 Eckstrum KS, Edwards W, Banerjee A, Wang W, Flaws JA, Katzenellenbogen JA, Kim SH, Raetzman LT. Effects of exposure to the endocrine disrupting chemical bisphenol A during critical windows of murine pituitary development. Endocrinology. PMID 29092056 DOI: 10.1210/en.2017-00565  0.48
2017 Katzenellenbogen BS, Zhao Y, Laws MJ, Sanabria Guillen V, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA. Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors. Cancer Research. PMID 28904064 DOI: 10.1158/0008-5472.CAN-17-1265  0.48
2017 Abid S, Xie S, Bose M, Shaul PW, Terada LS, Brody SL, Thomas PJ, Katzenellenbogen JA, Kim SH, Greenberg DE, Jain R. 17β-estradiol dysregulates innate immune responses to Pseudomonas aeruginosa respiratory infection and is modulated by estrogen receptor antagonism. Infection and Immunity. PMID 28784925 DOI: 10.1128/IAI.00422-17  0.48
2017 Min J, Guillen VS, Sharma A, Zhao Y, Ziegler Y, Gong P, Mayne CG, Srinivasan S, Kim SH, Carlson KE, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA. Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor (ER)-Mediated Activities in Breast Cancer Cells. Journal of Medicinal Chemistry. PMID 28657320 DOI: 10.1021/acs.jmedchem.7b00585  1
2017 Srinivasan S, Nwachukwu JC, Bruno NE, Dharmarajan V, Goswami D, Kastrati I, Novick S, Nowak J, Cavett V, Zhou HB, Boonmuen N, Zhao Y, Min J, Frasor J, Katzenellenbogen BS, ... ... Katzenellenbogen JA, et al. Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. 13: 691. PMID 28514424 DOI: 10.1038/nchembio0617-691c  0.64
2017 Srinivasan S, Nwachukwu JC, Bruno NE, Dharmarajan V, Goswami D, Kastrati I, Novick S, Nowak J, Cavett V, Zhou HB, Boonmuen N, Zhao Y, Min J, Frasor J, Katzenellenbogen BS, ... ... Katzenellenbogen JA, et al. Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. 13: 691. PMID 28514419 DOI: 10.1038/nchembio0617-691b  0.64
2017 Zhou D, Kim SH, Chu W, Voller T, Katzenellenbogen JA. Evaluation of Aromatic Radiobromination by Nucleophilic Substitution using Diaryliodonium Salt Precursors. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 28512784 DOI: 10.1002/jlcr.3519  0.48
2017 Menazza S, Sun J, Appachi S, Chambliss KL, Kim SH, Aponte A, Khan S, Katzenellenbogen JA, Katzenellenbogen BS, Shaul PW, Murphy E. Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice. Journal of Molecular and Cellular Cardiology. PMID 28457941 DOI: 10.1016/j.yjmcc.2017.04.004  0.48
2017 Madak-Erdogan Z, Charn TH, Jiang Y, Liu ET, Katzenellenbogen JA, Katzenellenbogen BS. Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Molecular Systems Biology. 13: 929. PMID 28442489  0.44
2017 Stender JD, Nwachukwu JC, Kastrati I, Kim Y, Strid T, Yakir M, Srinivasan S, Nowak J, Izard T, Rangarajan ES, Carlson KE, Katzenellenbogen JA, Yao XQ, Grant BJ, Leong HS, et al. Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. Molecular Cell. 65: 1122-1135.e5. PMID 28306507 DOI: 10.1016/j.molcel.2017.02.008  1
2017 Martin A, Yu J, Xiong J, Khalid AB, Katzenellenbogen B, Kim SH, Katzenellenbogen JA, Malaivijitnond S, Gabet Y, Krum SA, Frenkel B. Estrogens and Androgens Inhibit Association of RANKL with the Pre-osteoblast Membrane through Post-translational Mechanisms. Journal of Cellular Physiology. PMID 28213978 DOI: 10.1002/jcp.25862  0.48
2017 Christenson JL, Butterfield KT, Spoelstra NS, Norris JD, Josan JS, Pollock JA, McDonnell DP, Katzenellenbogen BS, Katzenellenbogen JA, Richer JK. MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression. Hormones & Cancer. PMID 28194662 DOI: 10.1007/s12672-017-0285-6  0.48
2017 Farman HH, Wu J, Gustafsson KL, Windahl SH, Kim SH, Katzenellenbogen JA, Ohlsson C, Lagerquist MK. Extra-nuclear effects of estrogen on cortical bone in males require ERαAF-1. Journal of Molecular Endocrinology. PMID 28057769 DOI: 10.1530/JME-16-0209  0.48
2016 Sharma N, Carlson KE, Nwachukwu JC, Srinivasan S, Sharma A, Nettles KW, Katzenellenbogen JA. Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands. Acs Chemical Biology. PMID 28032978 DOI: 10.1021/acschembio.6b00918  1
2016 Toy W, Weir H, Razavi P, Lawson M, Goeppert AU, Mazzola AM, Smith A, Wilson J, Morrow C, Wong WL, De Stanchina E, Carlson KE, Martin TS, Uddin S, Li Z, ... ... Katzenellenbogen JA, et al. Activating ESR1 Mutations Differentially Impact the Efficacy of ER Antagonists. Cancer Discovery. PMID 27986707 DOI: 10.1158/2159-8290.CD-15-1523  1
2016 Zhang S, Wang Z, Hu Z, Li C, Tang C, Carlson KE, Luo J, Dong C, Katzenellenbogen JA, Huang J, Zhou H. Selenophenes: Introducing a New Element into the Core of Non-Steroidal Estrogen Receptor Ligands. Chemmedchem. PMID 27976818 DOI: 10.1002/cmdc.201600593  1
2016 Srinivasan S, Nwachukwu JC, Bruno NE, Dharmarajan V, Goswami D, Kastrati I, Novick S, Nowak J, Cavett V, Zhou HB, Boonmuen N, Zhao Y, Min J, Frasor J, Katzenellenbogen BS, ... ... Katzenellenbogen JA, et al. Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nature Chemical Biology. PMID 27870835 DOI: 10.1038/nchembio.2236  0.64
2016 Chambliss KL, Barrera J, Umetani M, Umetani J, Kim SH, Madak-Erdogan Z, Huang L, Katzenellenbogen BS, Katzenellenbogen JA, Mineo C, Shaul PW. Non-Nuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice. Endocrinology. en20151629. PMID 27552247 DOI: 10.1210/en.2015-1629  0.72
2016 Gong P, Madak-Erdogan Z, Flaws JA, Shapiro DJ, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells. Molecular and Cellular Endocrinology. PMID 27543265 DOI: 10.1016/j.mce.2016.08.025  0.72
2016 Pollock JA, Wardell SE, Parent AA, Stagg DB, Ellison SJ, Alley HM, Chao CA, Lawrence SA, Stice JP, Spasojevic I, Baker JG, Kim SH, McDonnell DP, Katzenellenbogen JA, Norris JD. Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer. Nature Chemical Biology. PMID 27501397 DOI: 10.1038/nchembio.2131  0.72
2016 Madak-Erdogan Z, Kim SH, Gong P, Zhao YC, Zhang H, Chambliss KL, Carlson KE, Mayne CG, Shaul PW, Korach KS, Katzenellenbogen JA, Katzenellenbogen BS. Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues. Science Signaling. 9: ra53. PMID 27221711 DOI: 10.1126/scisignal.aad8170  0.72
2016 Katzenellenbogen BS, Katzenellenbogen JA, Madak-Erdogan Z, VanHook AM. Science Signaling podcast for 24 May 2016: Designer estrogens. Science Signaling. 9: pc12. PMID 27221709 DOI: 10.1126/scisignal.aag1040  0.72
2016 Granchi C, Lapillo M, Spena CR, Rizzolio F, Tuccinardi T, Martin TA, Carlson KE, Katzenellenbogen JA, Minutolo F. Cyclic Ketoximes as Estrogen Receptor β Selective Agonists. Chemmedchem. PMID 27135651 DOI: 10.1002/cmdc.201600140  0.72
2016 Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F. Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male. Cell Metabolism. PMID 27133133 DOI: 10.1016/j.cmet.2016.03.015  0.72
2016 Nwachukwu JC, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, Liao Z, Nowak J, Wright NJ, Houtman R, Carlson KE, Josan JS, Elemento O, Katzenellenbogen JA, Zhou HB, et al. Predictive features of ligand-specific signaling through the estrogen receptor. Molecular Systems Biology. 12: 864. PMID 27107013  1
2016 Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, et al. Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife. 5. PMID 26836308 DOI: 10.7554/eLife.12792  0.72
2016 Fowler AM, Clark AS, Katzenellenbogen JA, Linden HM, Dehdashti F. Imaging Diagnostic and Therapeutic Targets: Steroid Receptors in Breast Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 57: 75S-80S. PMID 26834106 DOI: 10.2967/jnumed.115.157933  0.72
2015 Xiong R, Patel HK, Gutgesell LM, Zhao J, Delgado-Rivera L, Pham TN, Zhao H, Carlson KE, Martin TA, Katzenellenbogen JA, Moore TW, Tonetti D, Thatcher GR. Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer. Journal of Medicinal Chemistry. PMID 26681208 DOI: 10.1021/acs.jmedchem.5b01276  0.72
2015 Zhao Y, Chen Y, Kuang Y, Bagchi MK, Taylor RN, Katzenellenbogen JA, Katzenellenbogen BS. Multiple Beneficial Roles of Repressor of Estrogen Receptor Activity (REA) in Suppressing the Progression of Endometriosis. Endocrinology. en20151324. PMID 26653759 DOI: 10.1210/en.2015-1324  0.72
2015 Boonmuen N, Gong P, Ali Z, Chittiboyina AG, Khan I, Doerge DR, Helferich WG, Carlson KE, Martin T, Piyachaturawat P, Katzenellenbogen JA, Katzenellenbogen BS. Licorice Root Components in Dietary Supplements are Selective Estrogen Receptor Modulators with a Spectrum of Estrogenic and Anti-Estrogenic Activities. Steroids. PMID 26631549 DOI: 10.1016/j.steroids.2015.11.006  0.72
2015 Madak-Erdogan Z, Gong P, Zhao YC, Xu L, Wrobel KU, Hartman JA, Wang M, Cam A, Iwaniec UT, Turner RT, Twaddle NC, Doerge DR, Khan IA, Katzenellenbogen JA, Katzenellenbogen BS, et al. Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland. Molecular Nutrition & Food Research. PMID 26555669 DOI: 10.1002/mnfr.201500445  0.44
2015 Yasui N, Mayne CG, Katzenellenbogen JA. Preparation of o-Fluorophenols from Nonaromatic Precursors: Mechanistic Considerations for Adaptation to Fluorine-18 Radiolabeling. Organic Letters. PMID 26536250 DOI: 10.1021/acs.orglett.5b02640  1
2015 Pollock JA, Kim SH, Katzenellenbogen JA. Imidoyl dichlorides as new reagents for the rapid formation of 2-aminobenzimidazoles and related azoles. Tetrahedron Letters. 56: 6097-6099. PMID 26516292 DOI: 10.1016/j.tetlet.2015.09.076  0.72
2015 Pisani SL, Neese SL, Katzenellenbogen JA, Schantz SL, Korol DL. ESTROGEN RECEPTOR SELECTIVE AGONISTS MODULATE LEARNING IN FEMALE RATS IN A DOSE- AND TASK-SPECIFIC MANNER. Endocrinology. en20151616. PMID 26465198 DOI: 10.1210/en.2015-1616  0.72
2015 Reilly DT, Kim SH, Katzenellenbogen JA, Schroeder CM. Fluorescent Nanoconjugate Derivatives with Enhanced Photostability for Single Molecule Imaging. Analytical Chemistry. PMID 26461122 DOI: 10.1021/acs.analchem.5b03059  0.72
2015 Granchi C, Qian Y, Lee HY, Paterni I, Pasero C, Iegre J, Carlson KE, Tuccinardi T, Chen X, Katzenellenbogen JA, Hergenrother PJ, Minutolo F. Salicylketoximes That Target Glucose Transporter 1 Restrict Energy Supply to Lung Cancer Cells. Chemmedchem. PMID 26332543 DOI: 10.1002/cmdc.201500320  0.72
2015 Smirnova NF, Fontaine C, Buscato M, Lupieri A, Vinel A, Valera MC, Guillaume M, Malet N, Foidart JM, Raymond-Letron I, Lenfant F, Gourdy P, Katzenellenbogen BS, Katzenellenbogen JA, Laffargue M, et al. The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells. Circulation Research. 117: 770-8. PMID 26316608 DOI: 10.1161/CIRCRESAHA.115.306416  0.72
2015 Durrant JD, Carlson KE, Martin TA, Offutt TL, Mayne CG, Katzenellenbogen JA, Amaro RE. Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands. Journal of Chemical Information and Modeling. 55: 1953-61. PMID 26286148 DOI: 10.1021/acs.jcim.5b00241  0.72
2015 Valéra MC, Fontaine C, Lenfant F, Cabou C, Guillaume M, Smirnova N, Kim SH, Chambon P, Katzenellenbogen JA, Katzenellenbogen BS, Payrastre B, Arnal JF. Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α. Endocrinology. 156: 4293-301. PMID 26280130 DOI: 10.1210/en.2015-1522  0.72
2015 Kim SH, Madak-Erdogan Z, Bae SC, Carlson KE, Mayne CG, Granick S, Katzenellenbogen BS, Katzenellenbogen JA. Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History. Journal of the American Chemical Society. PMID 26186415 DOI: 10.1021/jacs.5b05952  1
2015 Bosch A, Li Z, Bergamaschi A, Ellis H, Toska E, Prat A, Tao JJ, Spratt DE, Viola-Villegas NT, Castel P, Minuesa G, Morse N, Rodón J, Ibrahim Y, Cortes J, ... ... Katzenellenbogen JA, et al. PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer. Science Translational Medicine. 7: 283ra51. PMID 25877889 DOI: 10.1126/scitranslmed.aaa4442  1
2015 Moore TW, Gunther JR, Katzenellenbogen JA. Estrogen receptor alpha/co-activator interaction assay: TR-FRET. Methods in Molecular Biology (Clifton, N.J.). 1278: 545-53. PMID 25859975 DOI: 10.1007/978-1-4939-2425-7_36  0.72
2015 Zhao Y, Gong P, Chen Y, Nwachukwu JC, Srinivasan S, Ko C, Bagchi MK, Taylor RN, Korach KS, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS. Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis. Science Translational Medicine. 7: 271ra9. PMID 25609169 DOI: 10.1126/scitranslmed.3010626  1
2015 Paterni I, Bertini S, Granchi C, Tuccinardi T, Macchia M, Martinelli A, Caligiuri I, Toffoli G, Rizzolio F, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Minutolo F. Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model. Journal of Medicinal Chemistry. 58: 1184-94. PMID 25559213 DOI: 10.1021/jm501829f  1
2015 Chan SR, Fowler AM, Allen JA, Zhou D, Dence CS, Sharp TL, Fettig NM, Dehdashti F, Katzenellenbogen JA. Longitudinal noninvasive imaging of progesterone receptor as a predictive biomarker of tumor responsiveness to estrogen deprivation therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1063-70. PMID 25520392 DOI: 10.1158/1078-0432.CCR-14-1715  1
2015 Zhou D, Chu W, Peng X, McConathy J, Mach RH, Katzenellenbogen JA. Facile purification and click labeling with 2-[18F]fluoroethyl azide using solid phase extraction cartridges Tetrahedron Letters. 56: 952-954. DOI: 10.1016/j.tetlet.2014.10.126  1
2014 Moore SM, Khalaj AJ, Kumar S, Winchester Z, Yoon J, Yoo T, Martinez-Torres L, Yasui N, Katzenellenbogen JA, Tiwari-Woodruff SK. Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 111: 18061-6. PMID 25453074 DOI: 10.1073/pnas.1411294111  1
2014 Gong P, Madak-Erdogan Z, Li J, Cheng J, Greenlief CM, Helferich W, Katzenellenbogen JA, Katzenellenbogen BS. Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens. Nuclear Receptor Signaling. 12: e001. PMID 25363786 DOI: 10.1621/nrs.12001  0.44
2014 Zhou D, Kim SH, Carroll VM, Dence CS, Katzenellenbogen JA. Utilizing electrostatic interactions to facilitate F-18 radiolabeling of poly(amido)amine (PAMAM) dendrimers. Organic & Biomolecular Chemistry. 12: 8696-701. PMID 25254430 DOI: 10.1039/c4ob01616e  0.36
2014 Abot A, Fontaine C, Buscato M, Solinhac R, Flouriot G, Fabre A, Drougard A, Rajan S, Laine M, Milon A, Muller I, Henrion D, Adlanmerini M, Valéra MC, Gompel A, ... ... Katzenellenbogen JA, et al. The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation. Embo Molecular Medicine. 6: 1328-46. PMID 25214462 DOI: 10.15252/emmm.201404112  1
2014 Dabrota C, Asim M, Choueiri C, Gargaun A, Korobkov I, Butt A, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T. Synthesis and receptor binding in trans-CD ring-fused A-CD estrogens: comparison with the cis-fused isomers. Bioorganic & Medicinal Chemistry Letters. 24: 3841-4. PMID 25027938 DOI: 10.1016/j.bmcl.2014.06.066  1
2014 Paterni I, Granchi C, Katzenellenbogen JA, Minutolo F. Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential. Steroids. 90: 13-29. PMID 24971815 DOI: 10.1016/j.steroids.2014.06.012  1
2014 Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, Serra-Musach J, Islam A, Caizzi L, Di Croce L, Nevedomskaya E, Zwart W, Bostner J, Karlsson E, Pérez Tenorio G, ... ... Katzenellenbogen JA, et al. VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Research : Bcr. 16: R53. PMID 24886537 DOI: 10.1186/bcr3664  1
2014 Zhou D, Lin M, Yasui N, Al-Qahtani MH, Dence CS, Schwarz S, Katzenellenbogen JA. Optimization of the preparation of fluorine-18-labeled steroid receptor ligands 16alpha-[18F]fluoroestradiol (FES), [18F]fluoro furanyl norprogesterone (FFNP), and 16beta-[18F]fluoro-5alpha-dihydrotestosterone (FDHT) as radiopharmaceuticals. Journal of Labelled Compounds & Radiopharmaceuticals. 57: 371-7. PMID 24861984 DOI: 10.1002/jlcr.3191  1
2014 Parent AA, Ess DH, Katzenellenbogen JA. π-π interaction energies as determinants of the photodimerization of mono-, di-, and triazastilbenes. The Journal of Organic Chemistry. 79: 5448-62. PMID 24837276 DOI: 10.1021/jo500457n  1
2014 Li Z, Chen K, Jiao X, Wang C, Willmarth NE, Casimiro MC, Li W, Ju X, Kim SH, Lisanti MP, Katzenellenbogen JA, Pestell RG. Cyclin D1 integrates estrogen-mediated DNA damage repair signaling. Cancer Research. 74: 3959-70. PMID 24830723 DOI: 10.1158/0008-5472.CAN-13-3137  1
2014 Nwachukwu JC, Srinivasan S, Bruno NE, Parent AA, Hughes TS, Pollock JA, Gjyshi O, Cavett V, Nowak J, Garcia-Ordonez RD, Houtman R, Griffin PR, Kojetin DJ, Katzenellenbogen JA, Conkright MD, et al. Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife. 3: e02057. PMID 24771768 DOI: 10.7554/eLife.02057  1
2014 Royston SE, Yasui N, Kondilis AG, Lord SV, Katzenellenbogen JA, Mahoney MM. ESR1 and ESR2 differentially regulate daily and circadian activity rhythms in female mice. Endocrinology. 155: 2613-23. PMID 24735329 DOI: 10.1210/en.2014-1101  1
2014 Liao ZQ, Dong C, Carlson KE, Srinivasan S, Nwachukwu JC, Chesnut RW, Sharma A, Nettles KW, Katzenellenbogen JA, Zhou HB. Triaryl-substituted Schiff bases are high-affinity subtype-selective ligands for the estrogen receptor. Journal of Medicinal Chemistry. 57: 3532-45. PMID 24708493 DOI: 10.1021/jm500268j  1
2014 Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, et al. Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions. Proceedings of the National Academy of Sciences of the United States of America. 111: E283-90. PMID 24371309 DOI: 10.1073/pnas.1322057111  1
2013 Saint-Criq V, Kim SH, Katzenellenbogen JA, Harvey BJ. Non-genomic estrogen regulation of ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium. Plos One. 8: e78593. PMID 24223826 DOI: 10.1371/journal.pone.0078593  1
2013 Xing H, Tang L, Yang X, Hwang K, Wang W, Yin Q, Wong NY, Dobrucki LW, Yasui N, Katzenellenbogen JA, Helferich WG, Cheng J, Lu Y. Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 1: 5288-5297. PMID 24159374 DOI: 10.1039/C3TB20412J  1
2013 Wright JS, Anderson JM, Shadnia H, Durst T, Katzenellenbogen JA. Experimental versus predicted affinities for ligand binding to estrogen receptor: iterative selection and rescoring of docked poses systematically improves the correlation. Journal of Computer-Aided Molecular Design. 27: 707-21. PMID 23975271 DOI: 10.1007/s10822-013-9670-6  1
2013 Jiang Y, Gong P, Madak-Erdogan Z, Martin T, Jeyakumar M, Carlson K, Khan I, Smillie TJ, Chittiboyina AG, Rotte SC, Helferich WG, Katzenellenbogen JA, Katzenellenbogen BS. Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4406-18. PMID 23882126 DOI: 10.1096/fj.13-234617  1
2013 Madak-Erdogan Z, Charn TH, Jiang Y, Liu ET, Katzenellenbogen JA, Katzenellenbogen BS. Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Molecular Systems Biology. 9: 676. PMID 23774759 DOI: 10.1038/msb.2013.28  1
2013 Fan P, Griffith OL, Agboke FA, Anur P, Zou X, McDaniel RE, Creswell K, Kim SH, Katzenellenbogen JA, Gray JW, Jordan VC. c-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells. Cancer Research. 73: 4510-20. PMID 23704208 DOI: 10.1158/0008-5472.CAN-12-4152  1
2013 Min J, Wang P, Srinivasan S, Nwachukwu JC, Guo P, Huang M, Carlson KE, Katzenellenbogen JA, Nettles KW, Zhou HB. Thiophene-core estrogen receptor ligands having superagonist activity. Journal of Medicinal Chemistry. 56: 3346-66. PMID 23586645 DOI: 10.1021/jm400157e  1
2013 Josan JS, Katzenellenbogen JA. Designer antiandrogens join the race against drug resistance. Elife. 2: e00692. PMID 23580166 DOI: 10.7554/eLife.00692  1
2013 Kim Y, Kim SH, Tanyeri M, Katzenellenbogen JA, Schroeder CM. Dendrimer probes for enhanced photostability and localization in fluorescence imaging. Biophysical Journal. 104: 1566-75. PMID 23561533 DOI: 10.1016/j.bpj.2013.01.052  1
2013 Srinivasan S, Nwachukwu JC, Parent AA, Cavett V, Nowak J, Hughes TS, Kojetin DJ, Katzenellenbogen JA, Nettles KW. Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α. Nature Chemical Biology. 9: 326-32. PMID 23524984 DOI: 10.1038/nchembio.1214  1
2013 Bartell SM, Han L, Kim HN, Kim SH, Katzenellenbogen JA, Katzenellenbogen BS, Chambliss KL, Shaul PW, Roberson PK, Weinstein RS, Jilka RL, Almeida M, Manolagas SC. Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass. Molecular Endocrinology (Baltimore, Md.). 27: 649-56. PMID 23443267 DOI: 10.1210/me.2012-1368  1
2013 Shan M, Carlson KE, Bujotzek A, Wellner A, Gust R, Weber M, Katzenellenbogen JA, Haag R. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. Acs Chemical Biology. 8: 707-15. PMID 23312071 DOI: 10.1021/cb3006243  1
2013 Lee BC, Moon BS, Kim JS, Jung JH, Park HS, Katzenellenbogen JA, Kim SE. Synthesis and biological evaluation of RGD peptides with the 99mTc/188Re chelated iminodiacetate core: Highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis Rsc Advances. 3: 782-792. DOI: 10.1039/c2ra22460g  1
2012 Zhu M, Zhang C, Nwachukwu JC, Srinivasan S, Cavett V, Zheng Y, Carlson KE, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides. Organic & Biomolecular Chemistry. 10: 8692-700. PMID 23033157 DOI: 10.1039/c2ob26531a  1
2012 Sepehr E, Lebl-Rinnova M, Mann MK, Pisani SL, Churchwell MI, Korol DL, Katzenellenbogen JA, Doerge DR. Pharmacokinetics of the estrogen receptor subtype-selective ligands, PPT and DPN: quantification using UPLC-ES/MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 71: 119-26. PMID 22981216 DOI: 10.1016/j.jpba.2012.08.022  1
2012 Kim Y, Kim SH, Ferracane D, Katzenellenbogen JA, Schroeder CM. Specific labeling of zinc finger proteins using noncanonical amino acids and copper-free click chemistry. Bioconjugate Chemistry. 23: 1891-901. PMID 22871171 DOI: 10.1021/bc300262h  1
2012 Lee JH, Peters O, Lehmann L, Dence CS, Sharp TL, Carlson KE, Zhou D, Jeyakumar M, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of two agents for imaging estrogen receptor β by positron emission tomography: challenges in PET imaging of a low abundance target. Nuclear Medicine and Biology. 39: 1105-16. PMID 22749433 DOI: 10.1016/j.nucmedbio.2012.05.011  1
2012 Fowler AM, Chan SR, Sharp TL, Fettig NM, Zhou D, Dence CS, Carlson KE, Jeyakumar M, Katzenellenbogen JA, Schreiber RD, Welch MJ. Small-animal PET of steroid hormone receptors predicts tumor response to endocrine therapy using a preclinical model of breast cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1119-26. PMID 22669982 DOI: 10.2967/jnumed.112.103465  1
2012 Zeng D, Lee NS, Liu Y, Zhou D, Dence CS, Wooley KL, Katzenellenbogen JA, Welch MJ. 64Cu Core-labeled nanoparticles with high specific activity via metal-free click chemistry. Acs Nano. 6: 5209-19. PMID 22548282 DOI: 10.1021/nn300974s  1
2012 Asim M, Klonowska D, Choueiri C, Korobkov I, Carlson KE, Katzenellenbogen JA, Durst T. BC-spiro-estradiols. Synthesis and estrogen receptor binding affinity of four new estradiol isomers. Bioorganic & Medicinal Chemistry Letters. 22: 3713-7. PMID 22546676 DOI: 10.1016/j.bmcl.2012.04.022  1
2012 Zheng Y, Zhu M, Srinivasan S, Nwachukwu JC, Cavett V, Min J, Carlson KE, Wang P, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands. Chemmedchem. 7: 1094-100. PMID 22517684 DOI: 10.1002/cmdc.201200048  1
2012 Dehdashti F, Laforest R, Gao F, Aft RL, Dence CS, Zhou D, Shoghi KI, Siegel BA, Katzenellenbogen JA, Welch MJ. Assessment of progesterone receptors in breast carcinoma by PET with 21-18F-fluoro-16α,17α-[(R)-(1'-α-furylmethylidene)dioxy]-19-norpregn-4-ene-3,20-dione. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 363-70. PMID 22331216 DOI: 10.2967/jnumed.111.098319  1
2012 Wang P, Min J, Nwachukwu JC, Cavett V, Carlson KE, Guo P, Zhu M, Zheng Y, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Identification and structure-activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2.2.1]hept-2-ene-7-oxide. Journal of Medicinal Chemistry. 55: 2324-41. PMID 22283328 DOI: 10.1021/jm201556r  1
2012 Carroll VM, Jeyakumar M, Carlson KE, Katzenellenbogen JA. Diarylpropionitrile (DPN) enantiomers: synthesis and evaluation of estrogen receptor β-selective ligands. Journal of Medicinal Chemistry. 55: 528-37. PMID 22122563 DOI: 10.1021/jm201436k  1
2011 Miller CP, Shomali M, Lyttle CR, O'Dea LS, Herendeen H, Gallacher K, Paquin D, Compton DR, Sahoo B, Kerrigan SA, Burge MS, Nickels M, Green JL, Katzenellenbogen JA, Tchesnokov A, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. Acs Medicinal Chemistry Letters. 2: 124-9. PMID 24900290 DOI: 10.1021/ml1002508  1
2011 Paulmurugan R, Tamrazi A, Massoud TF, Katzenellenbogen JA, Gambhir SS. In vitro and in vivo molecular imaging of estrogen receptor α and β homo- and heterodimerization: exploration of new modes of receptor regulation. Molecular Endocrinology (Baltimore, Md.). 25: 2029-40. PMID 22052998 DOI: 10.1210/me.2011-1145  1
2011 McLachlan MJ, Katzenellenbogen JA, Zhao H. A new fluorescence complementation biosensor for detection of estrogenic compounds. Biotechnology and Bioengineering. 108: 2794-803. PMID 21732327 DOI: 10.1002/bit.23254  1
2011 Katzenellenbogen JA. The 2010 Philip S. Portoghese Medicinal Chemistry Lectureship: addressing the "core issue" in the design of estrogen receptor ligands. Journal of Medicinal Chemistry. 54: 5271-82. PMID 21707083 DOI: 10.1021/jm200801h  1
2011 Saijo K, Collier JG, Li AC, Katzenellenbogen JA, Glass CK. An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. Cell. 145: 584-95. PMID 21565615 DOI: 10.1016/j.cell.2011.03.050  1
2011 Bertini S, De Cupertinis A, Granchi C, Bargagli B, Tuccinardi T, Martinelli A, Macchia M, Gunther JR, Carlson KE, Katzenellenbogen JA, Minutolo F. Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes. European Journal of Medicinal Chemistry. 46: 2453-62. PMID 21481497 DOI: 10.1016/j.ejmech.2011.03.030  1
2011 Sun A, Moore TW, Gunther JR, Kim MS, Rhoden E, Du Y, Fu H, Snyder JP, Katzenellenbogen JA. Discovering small-molecule estrogen receptor α/coactivator binding inhibitors: high-throughput screening, ligand development, and models for enhanced potency. Chemmedchem. 6: 654-66. PMID 21365764 DOI: 10.1002/cmdc.201000507  1
2011 Jeyakumar M, Carlson KE, Gunther JR, Katzenellenbogen JA. Exploration of dimensions of estrogen potency: parsing ligand binding and coactivator binding affinities. The Journal of Biological Chemistry. 286: 12971-82. PMID 21321128 DOI: 10.1074/jbc.M110.205112  1
2011 Cheong SJ, Jang D, Jeong HJ, Lim ST, Sohn MH, Katzenellenbogen JA, Kim DW. Reduction of stimulated sodium iodide symporter expression by estrogen receptor ligands in breast cancer cells. Nuclear Medicine and Biology. 38: 287-94. PMID 21315285 DOI: 10.1016/j.nucmedbio.2010.07.010  1
2011 Wright JS, Shadnia H, Anderson JM, Durst T, Asim M, El-Salfiti M, Choueiri C, Pratt MA, Ruddy SC, Lau R, Carlson KE, Katzenellenbogen JA, O'Brien PJ, Wan L. A-CD estrogens. I. Substituent effects, hormone potency, and receptor subtype selectivity in a new family of flexible estrogenic compounds. Journal of Medicinal Chemistry. 54: 433-48. PMID 21190382 DOI: 10.1021/jm100513m  1
2011 Minutolo F, Macchia M, Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor β ligands: recent advances and biomedical applications. Medicinal Research Reviews. 31: 364-442. PMID 19967775 DOI: 10.1002/med.20186  1
2010 Bruning JB, Parent AA, Gil G, Zhao M, Nowak J, Pace MC, Smith CL, Afonine PV, Adams PD, Katzenellenbogen JA, Nettles KW. Coupling of receptor conformation and ligand orientation determine graded activity. Nature Chemical Biology. 6: 837-43. PMID 20924370 DOI: 10.1038/nchembio.451  1
2010 Moore TW, Gunther JR, Katzenellenbogen JA. Probing the topological tolerance of multimeric protein interactions: evaluation of an estrogen/synthetic ligand for FK506 binding protein conjugate. Bioconjugate Chemistry. 21: 1880-9. PMID 20919698 DOI: 10.1021/bc100266v  1
2010 Ackroyd NC, Katzenellenbogen JA. Pyridyl-Cyclopentadiene Re(CO)(2) Complexes as a Compact Core Systems for SPECT Ligand Development. Organometallics. 29: 3669-3671. PMID 20865134 DOI: 10.1021/om100521s  1
2010 Neese SL, Korol DL, Katzenellenbogen JA, Schantz SL. Impact of estrogen receptor alpha and beta agonists on delayed alternation in middle-aged rats. Hormones and Behavior. 58: 878-90. PMID 20816967 DOI: 10.1016/j.yhbeh.2010.08.017  1
2010 Santollo J, Katzenellenbogen BS, Katzenellenbogen JA, Eckel LA. Activation of ERα is necessary for estradiol's anorexigenic effect in female rats. Hormones and Behavior. 58: 872-7. PMID 20807534 DOI: 10.1016/j.yhbeh.2010.08.012  1
2010 Wong WP, Tiano JP, Liu S, Hewitt SC, Le May C, Dalle S, Katzenellenbogen JA, Katzenellenbogen BS, Korach KS, Mauvais-Jarvis F. Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 13057-62. PMID 20616010 DOI: 10.1073/pnas.0914501107  1
2010 Chambliss KL, Wu Q, Oltmann S, Konaniah ES, Umetani M, Korach KS, Thomas GD, Mineo C, Yuhanna IS, Kim SH, Madak-Erdogan Z, Maggi A, Dineen SP, Roland CL, Hui DY, ... ... Katzenellenbogen JA, et al. Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. The Journal of Clinical Investigation. 120: 2319-30. PMID 20577047 DOI: 10.1172/JCI38291  1
2010 Lee JH, Zhou HB, Dence CS, Carlson KE, Welch MJ, Katzenellenbogen JA. Development of [F-18]fluorine-substituted Tanaproget as a progesterone receptor imaging agent for positron emission tomography. Bioconjugate Chemistry. 21: 1096-104. PMID 20496889 DOI: 10.1021/bc1001054  1
2010 Zhou HB, Lee JH, Mayne CG, Carlson KE, Katzenellenbogen JA. Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget. Journal of Medicinal Chemistry. 53: 3349-60. PMID 20355713 DOI: 10.1021/jm100052k  1
2010 Kieser KJ, Kim DW, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs). Journal of Medicinal Chemistry. 53: 3320-9. PMID 20334372 DOI: 10.1021/jm100047k  1
2010 Kim SH, Gunther JR, Katzenellenbogen JA. Monitoring a coordinated exchange process in a four-component biological interaction system: development of a time-resolved terbium-based one-donor/three-acceptor multicolor FRET system. Journal of the American Chemical Society. 132: 4685-92. PMID 20230029 DOI: 10.1021/ja100248q  1
2010 Moore TW, Mayne CG, Katzenellenbogen JA. Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs). Molecular Endocrinology (Baltimore, Md.). 24: 683-95. PMID 19933380 DOI: 10.1210/me.2009-0362  1
2010 Charn TH, Liu ET, Chang EC, Lee YK, Katzenellenbogen JA, Katzenellenbogen BS. Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection. Molecular Endocrinology (Baltimore, Md.). 24: 47-59. PMID 19897598 DOI: 10.1210/me.2009-0252  1
2010 Zeng CM, Kerrigan SA, Katzenellenbogen JA, Slocum C, Gallacher K, Shomali M, Lyttle CR, Hattersley G, Miller CP. Efficient synthesis of (2R,3S)-2-amino-3-(benzyloxy)-4,4,4- trifluorobutanoic acid (4,4,4-trifluoro-OBn-d-allothreonine) Tetrahedron Letters. 51: 5361-5363. DOI: 10.1016/j.tetlet.2010.07.147  1
2009 Williams AB, Weiser PT, Hanson RN, Gunther JR, Katzenellenbogen JA. Synthesis of biphenyl proteomimetics as estrogen receptor-alpha coactivator binding inhibitors. Organic Letters. 11: 5370-3. PMID 19902964 DOI: 10.1021/ol901999f  1
2009 Gunther JR, Parent AA, Katzenellenbogen JA. Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors. Acs Chemical Biology. 4: 435-40. PMID 19441848 DOI: 10.1021/cb900043e  1
2009 LaFrate AL, Carlson KE, Katzenellenbogen JA. Steroidal bivalent ligands for the estrogen receptor: design, synthesis, characterization and binding affinities. Bioorganic & Medicinal Chemistry. 17: 3528-35. PMID 19394231 DOI: 10.1016/j.bmc.2009.04.016  1
2009 Waibel M, Kieser KJ, Carlson KE, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA. Phenethyl pyridines with non-polar internal substituents as selective ligands for estrogen receptor beta. European Journal of Medicinal Chemistry. 44: 3560-70. PMID 19394116 DOI: 10.1016/j.ejmech.2009.03.013  1
2009 Moon BS, Carlson KE, Katzenellenbogen JA, Choi TH, Chi DY, Kim JY, Cheon GJ, Koh HY, Lee KC, An G. Synthesis and evaluation of aryl-substituted diarylpropionitriles, selective ligands for estrogen receptor beta, as positron-emission tomographic imaging agents. Bioorganic & Medicinal Chemistry. 17: 3479-88. PMID 19359182 DOI: 10.1016/j.bmc.2009.02.064  1
2009 Waibel M, De Angelis M, Stossi F, Kieser KJ, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta. European Journal of Medicinal Chemistry. 44: 3412-24. PMID 19286283 DOI: 10.1016/j.ejmech.2009.02.006  1
2009 Zhou D, Zhou H, Jenks CC, Lewis JS, Katzenellenbogen JA, Welch MJ. Bromination from the macroscopic level to the tracer radiochemical level: (76)Br radiolabeling of aromatic compounds via electrophilic substitution. Bioconjugate Chemistry. 20: 808-16. PMID 19260733 DOI: 10.1021/bc800313c  1
2009 Lee BC, Dence CS, Zhou H, Parent EE, Welch MJ, Katzenellenbogen JA. Fluorine-18 labeling and biodistribution studies on peroxisome proliferator-activated receptor-gamma ligands: potential positron emission tomography imaging agents. Nuclear Medicine and Biology. 36: 147-53. PMID 19217526 DOI: 10.1016/j.nucmedbio.2008.11.002  1
2009 Gunther JR, Du Y, Rhoden E, Lewis I, Revennaugh B, Moore TW, Kim SH, Dingledine R, Fu H, Katzenellenbogen JA. A set of time-resolved fluorescence resonance energy transfer assays for the discovery of inhibitors of estrogen receptor-coactivator binding. Journal of Biomolecular Screening. 14: 181-93. PMID 19196699 DOI: 10.1177/1087057108329349  1
2009 Asim M, Asim M, El-Salfiti M, Qian Y, Choueiri C, Salari S, Cheng J, Shadnia H, Bal M, Christine Pratt MA, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T. Deconstructing estradiol: removal of B-ring generates compounds which are potent and subtype-selective estrogen receptor agonists. Bioorganic & Medicinal Chemistry Letters. 19: 1250-3. PMID 19167882 DOI: 10.1016/j.bmcl.2008.12.080  1
2009 Minutolo F, Bertini S, Granchi C, Marchitiello T, Prota G, Rapposelli S, Tuccinardi T, Martinelli A, Gunther JR, Carlson KE, Katzenellenbogen JA, Macchia M. Structural evolutions of salicylaldoximes as selective agonists for estrogen receptor beta. Journal of Medicinal Chemistry. 52: 858-67. PMID 19128016 DOI: 10.1021/jm801458t  1
2009 Jeyakumar M, Katzenellenbogen JA. A dual-acceptor time-resolved Föster resonance energy transfer assay for simultaneous determination of thyroid hormone regulation of corepressor and coactivator binding to the thyroid hormone receptor: Mimicking the cellular context of thyroid hormone action. Analytical Biochemistry. 386: 73-8. PMID 19111515 DOI: 10.1016/j.ab.2008.11.039  1
2009 Kim SH, Ge P, Katzenellenbogen JA. A new quinoline sensitizer-centered lanthanide chelate and its use for protein labling on Ni-NTA beads for TR LRET assays. Chemical Communications (Cambridge, England). 183-5. PMID 19099062 DOI: 10.1039/b814980a  1
2009 Trogden BG, Kim SH, Lee S, Katzenellenbogen JA. Tethered indoles as functionalizable ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 19: 485-8. PMID 19059778 DOI: 10.1016/j.bmcl.2008.11.043  1
2009 Zhou HB, Carlson KE, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA. Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity. Bioorganic & Medicinal Chemistry Letters. 19: 108-10. PMID 19014882 DOI: 10.1016/j.bmcl.2008.11.006  1
2009 Dehdashti F, Mortimer JE, Trinkaus K, Naughton MJ, Ellis M, Katzenellenbogen JA, Welch MJ, Siegel BA. PET-based estradiol challenge as a predictive biomarker of response to endocrine therapy in women with estrogen-receptor-positive breast cancer. Breast Cancer Research and Treatment. 113: 509-17. PMID 18327670 DOI: 10.1007/s10549-008-9953-0  1
2009 Moore TW, Katzenellenbogen JA. Inhibitors of nuclear hormone receptor/coactivator interactions Annual Reports in Medicinal Chemistry. 44: 443-457. DOI: 10.1016/S0065-7743(09)04421-2  1
2009 Asim M, El-Salfiti M, Qian Y, Choueiri C, Salari S, Cheng J, Shadnia H, Bal M, Christine Pratt MA, Carlson KE, Katzenellenbogen JA, Wright JS, Durst T. Corrigendum to "Deconstructing estradiol: Removal of B-ring generates compounds which are potent and subtype-selective estrogen receptor agonists" [Bioorg. Med. Chem. Lett. 19 (2009) 1250-1253] (DOI:10.1016/j.bmcl.2008.12.080) Bioorganic and Medicinal Chemistry Letters. 19: 2605. DOI: 10.1016/j.bmcl.2008.12.117  1
2008 LaFrate AL, Gunther JR, Carlson KE, Katzenellenbogen JA. Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor. Bioorganic & Medicinal Chemistry. 16: 10075-84. PMID 18976929 DOI: 10.1016/j.bmc.2008.10.007  1
2008 Kim SH, Gunther JR, Katzenellenbogen JA. Nonclassical SNAPFL analogue as a Cy5 resonance energy transfer partner. Organic Letters. 10: 4931-4. PMID 18841988 DOI: 10.1021/ol801907b  1
2008 Parent AA, Gunther JR, Katzenellenbogen JA. Blocking estrogen signaling after the hormone: pyrimidine-core inhibitors of estrogen receptor-coactivator binding. Journal of Medicinal Chemistry. 51: 6512-30. PMID 18785725 DOI: 10.1021/jm800698b  1
2008 Zhou D, Sharp TL, Fettig NM, Lee H, Lewis JS, Katzenellenbogen JA, Welch MJ. Evaluation of a bromine-76-labeled progestin 16alpha,17alpha-dioxolane for breast tumor imaging and radiotherapy: in vivo biodistribution and metabolic stability studies. Nuclear Medicine and Biology. 35: 655-63. PMID 18678350 DOI: 10.1016/j.nucmedbio.2008.05.001  1
2008 Madak-Erdogan Z, Kieser KJ, Kim SH, Komm B, Katzenellenbogen JA, Katzenellenbogen BS. Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors. Molecular Endocrinology (Baltimore, Md.). 22: 2116-27. PMID 18617595 DOI: 10.1210/me.2008-0059  1
2008 Jeyakumar M, Webb P, Baxter JD, Scanlan TS, Katzenellenbogen JA. Quantification of ligand-regulated nuclear receptor corepressor and coactivator binding, key interactions determining ligand potency and efficacy for the thyroid hormone receptor. Biochemistry. 47: 7465-76. PMID 18558711 DOI: 10.1021/bi800393u  1
2008 Alyea RA, Laurence SE, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Watson CS. The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells. Journal of Neurochemistry. 106: 1525-33. PMID 18489713 DOI: 10.1111/j.1471-4159.2008.05491.x  1
2008 Gunther JR, Moore TW, Collins ML, Katzenellenbogen JA. Amphipathic benzenes are designed inhibitors of the estrogen receptor alpha/steroid receptor coactivator interaction. Acs Chemical Biology. 3: 282-6. PMID 18484708 DOI: 10.1021/cb800056r  1
2008 Parent EE, Dence CS, Sharp TL, Welch MJ, Katzenellenbogen JA. 7alpha-18F-fluoromethyl-dihydrotestosterone and 7alpha-18F-fluoromethyl-nortestosterone: ligands to determine the role of sex hormone-binding globulin for steroidal radiopharmaceuticals. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 987-94. PMID 18483103 DOI: 10.2967/jnumed.107.048926  1
2008 Paulmurugan R, Tamrazi A, Katzenellenbogen JA, Katzenellenbogen BS, Gambhir SS. A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action. Molecular Endocrinology (Baltimore, Md.). 22: 1552-64. PMID 18451095 DOI: 10.1210/me.2007-0570  1
2008 Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachmiak A, Greene GL. NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses. Nature Chemical Biology. 4: 241-7. PMID 18344977 DOI: 10.1038/nchembio.76  1
2008 Minutolo F, Bellini R, Bertini S, Carboni I, Lapucci A, Pistolesi L, Prota G, Rapposelli S, Solati F, Tuccinardi T, Martinelli A, Stossi F, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, et al. Monoaryl-substituted salicylaldoximes as ligands for estrogen receptor beta. Journal of Medicinal Chemistry. 51: 1344-51. PMID 18269232 DOI: 10.1021/jm701396g  1
2008 Chang EC, Charn TH, Park SH, Helferich WG, Komm B, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding. Molecular Endocrinology (Baltimore, Md.). 22: 1032-43. PMID 18258689 DOI: 10.1210/me.2007-0356  1
2008 Kim DW, Jeong HJ, Lim ST, Sohn MH, Katzenellenbogen JA, Chi DY. Facile nucleophilic fluorination reactions using tert-alcohols as a reaction medium: significantly enhanced reactivity of alkali metal fluorides and improved selectivity. The Journal of Organic Chemistry. 73: 957-62. PMID 18166063 DOI: 10.1021/jo7021229  1
2008 Seo JW, Kim HJ, Lee BS, Katzenellenbogen JA, Chi DY. Convenient one-pot synthesis of 2,2-bis-(4-hydroxyphenyl)-cyclopentanone. The Journal of Organic Chemistry. 73: 715-8. PMID 18088140 DOI: 10.1021/jo701850u  1
2008 Wuest F, Carlson KE, Katzenellenbogen JA. Expeditious synthesis of steroids containing a 2-methylsulfanyl-acetyl side chain as potential glucocorticoid receptor imaging agents. Steroids. 73: 69-76. PMID 17942130 DOI: 10.1016/j.steroids.2007.08.013  1
2008 Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachimiak A, Greene GL. Corrigendum: NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses (Nature Chemical Biology (2008) 4, (241-247)) Nature Chemical Biology. 4: 379. DOI: 10.1038/nchembio0608-379b  1
2008 Byung SM, Katzenellenbogen JA, Gi JC, Dae YC, Kyo CL, Gwang IA. Synthesis and evaluation of estrogen receptor β-selective ligands: Fluoroalkylated indazole estrogens Bulletin of the Korean Chemical Society. 29: 1107-1114.  1
2007 Kim SH, Jeyakumar M, Katzenellenbogen JA. Dual-mode fluorophore-doped nickel nitrilotriacetic acid-modified silica nanoparticles combine histidine-tagged protein purification with site-specific fluorophore labeling. Journal of the American Chemical Society. 129: 13254-64. PMID 17910454 DOI: 10.1021/ja074443f  1
2007 LaFrate AL, Katzenellenbogen JA. Improved chemical syntheses of 5,6-dihydro-5-fluorouracil. The Journal of Organic Chemistry. 72: 8573-6. PMID 17900141 DOI: 10.1021/jo071255z  1
2007 Parent EE, Carlson KE, Katzenellenbogen JA. Synthesis of 7alpha-(fluoromethyl)dihydrotestosterone and 7alpha-(fluoromethyl)nortestosterone, structurally paired androgens designed to probe the role of sex hormone binding globulin in imaging androgen receptors in prostate tumors by positron emission tomography. The Journal of Organic Chemistry. 72: 5546-54. PMID 17585812 DOI: 10.1021/jo070328b  1
2007 Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA. Elemental Isomerism: A Boron-Nitrogen Surrogate for a Carbon-Carbon Double Bond Increases the Chemical Diversity of Estrogen Receptor Ligands Chemistry and Biology. 14: 659-669. PMID 17584613 DOI: 10.1016/j.chembiol.2007.04.009  1
2007 Zhou HB, Collins ML, Gunther JR, Comninos JS, Katzenellenbogen JA. Bicyclo[2.2.2]octanes: close structural mimics of the nuclear receptor-binding motif of steroid receptor coactivators. Bioorganic & Medicinal Chemistry Letters. 17: 4118-22. PMID 17560105 DOI: 10.1016/j.bmcl.2007.05.058  1
2007 Seo JW, Chi DY, Dence CS, Welch MJ, Katzenellenbogen JA. Synthesis and biodistribution of fluorine-18-labeled fluorocyclofenils for imaging the estrogen receptor. Nuclear Medicine and Biology. 34: 383-90. PMID 17499727 DOI: 10.1016/j.nucmedbio.2007.01.010  1
2007 Parent EE, Dence CS, Jenks C, Sharp TL, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of [18F]bicalutamide, 4-[76Br]bromobicalutamide, and 4-[76Br]bromo-thiobicalutamide as non-steroidal androgens for prostate cancer imaging. Journal of Medicinal Chemistry. 50: 1028-40. PMID 17328524 DOI: 10.1021/jm060847r  1
2007 Lee BC, Lee KC, Lee H, Mach RH, Katzenellenbogen JA. Strategies for the labeling of halogen-substituted peroxisome proliferator-activated receptor gamma ligands: potential positron emission tomography and single photon emission computed tomography imaging agents. Bioconjugate Chemistry. 18: 514-23. PMID 17315977 DOI: 10.1021/bc060191g  1
2007 Lee BC, Lee KC, Lee H, Mach RH, Katzenellenbogen JA. Synthesis and binding affinity of a fluorine-substituted peroxisome proliferator-activated gamma (PPARgamma) ligand as a potential positron emission tomography (PET) imaging agent. Bioconjugate Chemistry. 18: 507-13. PMID 17309226 DOI: 10.1021/bc060190o  1
2007 Zhou HB, Sheng S, Compton DR, Kim Y, Joachimiak A, Sharma S, Carlson KE, Katzenellenbogen BS, Nettles KW, Greene GL, Katzenellenbogen JA. Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains. Journal of Medicinal Chemistry. 50: 399-403. PMID 17228884 DOI: 10.1021/jm061035y  1
2006 Dahlman-Wright K, Cavailles V, Fuqua SA, Jordan VC, Katzenellenbogen JA, Korach KS, Maggi A, Muramatsu M, Parker MG, Gustafsson JA. International Union of Pharmacology. LXIV. Estrogen receptors. Pharmacological Reviews. 58: 773-81. PMID 17132854 DOI: 10.1124/pr.58.4.8  1
2006 Ramesh C, Bryant B, Nayak T, Revankar CM, Anderson T, Carlson KE, Katzenellenbogen JA, Sklar LA, Norenberg JP, Prossnitz ER, Arterburn JB. Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates. Journal of the American Chemical Society. 128: 14476-7. PMID 17090028 DOI: 10.1021/ja066360p  1
2006 Kim SH, Katzenellenbogen JA. Hormone-PAMAM dendrimer conjugates: polymer dynamics and tether structure affect ligand access to receptors. Angewandte Chemie (International Ed. in English). 45: 7243-8. PMID 17024710 DOI: 10.1002/anie.200601923  1
2006 Likhite VS, Stossi F, Kim K, Katzenellenbogen BS, Katzenellenbogen JA. Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity. Molecular Endocrinology (Baltimore, Md.). 20: 3120-32. PMID 16945990 DOI: 10.1210/me.2006-0068  1
2006 Parent EE, Jenks C, Sharp T, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide. Nuclear Medicine and Biology. 33: 705-13. PMID 16934689 DOI: 10.1016/j.nucmedbio.2006.05.009  1
2006 Jacobson O, Laky D, Carlson KE, Elgavish S, Gozin M, Even-Sapir E, Leibovitc I, Gutman M, Chisin R, Katzenellenbogen JA, Mishani E. Chiral dimethylamine flutamide derivatives--modeling, synthesis, androgen receptor affinities and carbon-11 labeling. Nuclear Medicine and Biology. 33: 695-704. PMID 16934688 DOI: 10.1016/j.nucmedbio.2006.05.010  1
2006 Tuccinardi T, Bertini S, Martinelli A, Minutolo F, Ortore G, Placanica G, Prota G, Rapposelli S, Carlson KE, Katzenellenbogen JA, Macchia M. Synthesis of anthranylaldoxime derivatives as estrogen receptor ligands and computational prediction of binding modes. Journal of Medicinal Chemistry. 49: 5001-12. PMID 16884312 DOI: 10.1021/jm060560u  1
2006 Zhou D, Carlson KE, Katzenellenbogen JA, Welch MJ. Bromine- and iodine-substituted 16alpha,17alpha-dioxolane progestins for breast tumor imaging and radiotherapy: synthesis and receptor binding affinity. Journal of Medicinal Chemistry. 49: 4737-44. PMID 16854080 DOI: 10.1021/jm060348q  1
2006 Parent EE, Dence CS, Sharp TL, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of a fluorine-18-labeled nonsteroidal androgen receptor antagonist, N-(3-[18F]fluoro-4-nitronaphthyl)-cis-5-norbornene-endo-2,3-dicarboxylic imide. Nuclear Medicine and Biology. 33: 615-24. PMID 16843836 DOI: 10.1016/j.nucmedbio.2006.04.003  1
2006 Dayan G, Lupien M, Auger A, Anghel SI, Rocha W, Croisetière S, Katzenellenbogen JA, Mader S. Tamoxifen and raloxifene differ in their functional interactions with aspartate 351 of estrogen receptor alpha. Molecular Pharmacology. 70: 579-88. PMID 16679488 DOI: 10.1124/mol.105.021931  1
2006 Seo JW, Comninos JS, Chi DY, Kim DW, Carlson KE, Katzenellenbogen JA. Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer. Journal of Medicinal Chemistry. 49: 2496-511. PMID 16610793 DOI: 10.1021/jm0512037  1
2006 Stossi F, Likhite VS, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter. The Journal of Biological Chemistry. 281: 16272-8. PMID 16608856 DOI: 10.1074/jbc.M513405200  1
2006 Harrington WR, Kim SH, Funk CC, Madak-Erdogan Z, Schiff R, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action. Molecular Endocrinology (Baltimore, Md.). 20: 491-502. PMID 16306086 DOI: 10.1210/me.2005-0186  1
2006 Mishra RG, Stanczyk FZ, Burry KA, Oparil S, Katzenellenbogen BS, Nealen ML, Katzenellenbogen JA, Hermsmeyer RK. Metabolite ligands of estrogen receptor-beta reduce primate coronary hyperreactivity. American Journal of Physiology. Heart and Circulatory Physiology. 290: H295-303. PMID 16199482 DOI: 10.1152/ajpheart.00468.2005  1
2006 Minutolo F, Bertini S, Martinelli A, Ortore G, Placanica G, Prota G, Rapposelli S, Tuccinardi T, Sheng S, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Macchia M. Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands Arkivoc. 2006: 83-94.  1
2005 Zhou HB, Comninos JS, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA. Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure. Journal of Medicinal Chemistry. 48: 7261-74. PMID 16279785 DOI: 10.1021/jm0506773  1
2005 Yoo J, Dence CS, Sharp TL, Katzenellenbogen JA, Welch MJ. Synthesis of an estrogen receptor beta-selective radioligand: 5-[18F]fluoro-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile and comparison of in vivo distribution with 16alpha-[18F]fluoro-17beta-estradiol. Journal of Medicinal Chemistry. 48: 6366-78. PMID 16190762 DOI: 10.1021/jm050121f  1
2005 De Angelis M, Stossi F, Waibel M, Katzenellenbogen BS, Katzenellenbogen JA. Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites. Bioorganic & Medicinal Chemistry. 13: 6529-42. PMID 16099659 DOI: 10.1016/j.bmc.2005.07.014  1
2005 Katzenellenbogen JA. Designing effective hybrid toxins. Chemistry & Biology. 12: 719-21. PMID 16039518 DOI: 10.1016/j.chembiol.2005.07.002  1
2005 Chockalingam K, Chen Z, Katzenellenbogen JA, Zhao H. Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches. Proceedings of the National Academy of Sciences of the United States of America. 102: 5691-6. PMID 15811944 DOI: 10.1073/pnas.0409206102  1
2005 Bigott HM, Parent E, Luyt LG, Katzenellenbogen JA, Welch MJ. Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors. Bioconjugate Chemistry. 16: 255-64. PMID 15769078 DOI: 10.1021/bc049770g  1
2005 Dehdashti F, Picus J, Michalski JM, Dence CS, Siegel BA, Katzenellenbogen JA, Welch MJ. Positron tomographic assessment of androgen receptors in prostatic carcinoma. European Journal of Nuclear Medicine and Molecular Imaging. 32: 344-50. PMID 15726353 DOI: 10.1007/s00259-005-1764-5  1
2005 De Angelis M, Stossi F, Carlson KA, Katzenellenbogen BS, Katzenellenbogen JA. Indazole estrogens: highly selective ligands for the estrogen receptor beta. Journal of Medicinal Chemistry. 48: 1132-44. PMID 15715479 DOI: 10.1021/jm049223g  1
2005 Tamrazi A, Carlson KE, Rodriguez AL, Katzenellenbogen JA. Coactivator proteins as determinants of estrogen receptor structure and function: spectroscopic evidence for a novel coactivator-stabilized receptor conformation. Molecular Endocrinology (Baltimore, Md.). 19: 1516-28. PMID 15661830 DOI: 10.1210/me.2004-0458  1
2005 Kim SH, Tamrazi A, Carlson KE, Katzenellenbogen JA. A proteomic microarray approach for exploring ligand-initiated nuclear hormone receptor pharmacology, receptor selectivity, and heterodimer functionality. Molecular & Cellular Proteomics : McP. 4: 267-77. PMID 15613364 DOI: 10.1074/mcp.M400192-MCP200  1
2005 Chu CK, Kim JH, Kim DW, Chung KH, Katzenellenbogen JA, Chi DY. Aromatic fluorination by decomposition of triazenes in ionic liquids Bulletin of the Korean Chemical Society. 26: 599-602.  1
2004 Zaitseva M, Yue DS, Katzenellenbogen JA, Rogers PA, Gargett CE. Estrogen receptor-alpha agonists promote angiogenesis in human myometrial microvascular endothelial cells. Journal of the Society For Gynecologic Investigation. 11: 529-35. PMID 15582497 DOI: 10.1016/j.jsgi.2004.06.004  1
2004 Compton DR, Sheng S, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. Journal of Medicinal Chemistry. 47: 5872-93. PMID 15537344 DOI: 10.1021/jm049631k  1
2004 De Angelis M, Katzenellenbogen JA. Ring nitrogen-substituted non-steroidal estrogens: pyridine and pyrimidine analogs of the phenol in deoxyhexestrol experience resonance constraints on preferred ligand conformation. Bioorganic & Medicinal Chemistry Letters. 14: 5835-9. PMID 15501051 DOI: 10.1016/j.bmcl.2004.09.048  1
2004 Compton DR, Carlson KE, Katzenellenbogen JA. Pyrazolo[1,5-a]pyrimidines as estrogen receptor ligands: defining the orientation of a novel heterocyclic core. Bioorganic & Medicinal Chemistry Letters. 14: 5681-4. PMID 15482947 DOI: 10.1016/j.bmcl.2004.08.046  1
2004 Mueller SO, Katzenellenbogen JA, Korach KS. Endogenous estrogen receptor beta is transcriptionally active in primary ovarian cells from estrogen receptor knockout mice. Steroids. 69: 681-6. PMID 15465114 DOI: 10.1016/j.steroids.2004.06.004  1
2004 Spera D, Cabrera G, Fiaschi R, Carlson KE, Katzenellenbogen JA, Napolitano E. Estradiol derivatives bearing sulfur-containing substituents at the 11beta or 7alpha positions: versatile reagents for the preparation of estrogen conjugates. Bioorganic & Medicinal Chemistry. 12: 4393-401. PMID 15265491 DOI: 10.1016/j.bmc.2004.06.017  1
2004 Minutolo F, Antonello M, Bertini S, Placanica G, Rapposelli S, Carlson KE, Katzenellenbogen JA, Macchia M. Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands Farmaco. 59: 601-607. PMID 15262529 DOI: 10.1016/j.farmac.2004.01.007  1
2004 Chen Z, Katzenellenbogen BS, Katzenellenbogen JA, Zhao H. Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity. The Journal of Biological Chemistry. 279: 33855-64. PMID 15159406 DOI: 10.1074/jbc.M402118200  1
2004 Selvaraj V, Zakroczymski MA, Naaz A, Mukai M, Ju YH, Doerge DR, Katzenellenbogen JA, Helferich WG, Cooke PS. Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice. Biology of Reproduction. 71: 966-72. PMID 15151933 DOI: 10.1095/biolreprod.104.029512  1
2004 Kim SH, Tamrazi A, Carlson KE, Daniels JR, Lee IY, Katzenellenbogen JA. Estrogen receptor microarrays: subtype-selective ligand binding. Journal of the American Chemical Society. 126: 4754-5. PMID 15080660 DOI: 10.1021/ja039586q  1
2004 Pedersen SB, Kristensen K, Hermann PA, Katzenellenbogen JA, Richelsen B. Estrogen controls lipolysis by up-regulating α2A-adrenergic receptors directly in human adipose tissue through the estrogen receptor α. Implications for the female fat distribution Journal of Clinical Endocrinology and Metabolism. 89: 1869-1878. PMID 15070958 DOI: 10.1210/jc.2003-031327  1
2004 Tsai HW, Katzenellenbogen JA, Katzenellenbogen BS, Shupnik MA. Protein kinase A activation of estrogen receptor α transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation Endocrinology. 145: 2730-2738. PMID 15033909 DOI: 10.1210/en.2003-1470  1
2004 Muthyala RS, Ju YH, Sheng S, Williams LD, Doerge DR, Katzenellenbogen BS, Helferich WG, Katzenellenbogen JA. Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta. Bioorganic & Medicinal Chemistry. 12: 1559-67. PMID 15018930 DOI: 10.1016/j.bmc.2003.11.035  1
2004 Nettles KW, Sun J, Radek JT, Sheng S, Rodriguez AL, Katzenellenbogen JA, Katzenellenbogen BS, Greene GL. Allosteric Control of Ligand Selectivity between Estrogen Receptors α and β: Implications for Other Nuclear Receptors Molecular Cell. 13: 317-327. PMID 14967140 DOI: 10.1016/S1097-2765(04)00054-1  1
2004 Hurth KM, Nilges MJ, Carlson KE, Tamrazi A, Belford RL, Katzenellenbogen JA. Ligand-induced changes in estrogen receptor conformation as measured by site-directed spin labeling. Biochemistry. 43: 1891-907. PMID 14967030 DOI: 10.1021/bi035566p  1
2004 Rodriguez AL, Tamrazi A, Collins ML, Katzenellenbogen JA. Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor alpha coactivator binding. Journal of Medicinal Chemistry. 47: 600-11. PMID 14736241 DOI: 10.1021/jm030404c  1
2003 Muthyala RS, Carlson KE, Katzenellenbogen JA. Exploration of the bicyclo[3.3.1]nonane system as a template for the development of new ligands for the estrogen receptor Bioorganic and Medicinal Chemistry Letters. 13: 4485-4488. PMID 14643352 DOI: 10.1016/j.bmcl.2003.08.061  1
2003 Tamrazi A, Katzenellenbogen JA. Site-specific fluorescent labeling of estrogen receptors and structure-activity relationships of ligands in terms of receptor dimer stability. Methods in Enzymology. 364: 37-53. PMID 14631838 DOI: 10.1016/S0076-6879(03)64003-6  1
2003 Luyt LG, Bigott HM, Welch MJ, Katzenellenbogen JA. 7alpha- and 17alpha-substituted estrogens containing tridentate tricarbonyl rhenium/technetium complexes: synthesis of estrogen receptor imaging agents and evaluation using microPET with technetium-94m. Bioorganic & Medicinal Chemistry. 11: 4977-89. PMID 14604660 DOI: 10.1016/j.bmc.2003.09.004  1
2003 Minutolo F, Antonello M, Bertini S, Ortore G, Placanica G, Rapposelli S, Sheng S, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Macchia M. Novel estrogen receptor ligands based on an anthranylaldoxime structure: Role of the phenol-type pseudocycle in the binding process Journal of Medicinal Chemistry. 46: 4032-4042. PMID 12954056 DOI: 10.1021/jm0308390  1
2003 Tamrazi A, Carlson KE, Katzenellenbogen JA. Molecular sensors of estrogen receptor conformations and dynamics. Molecular Endocrinology (Baltimore, Md.). 17: 2593-602. PMID 12947047 DOI: 10.1210/me.2003-0239  1
2003 Arterburn JB, Corona C, Rao KV, Carlson KE, Katzenellenbogen JA. Synthesis of 17-alpha-substituted estradiol-pyridin-2-yl hydrazine conjugates as effective ligands for labeling with Alberto's complex fac-[Re(OH2)3(CO)3]+ in water. The Journal of Organic Chemistry. 68: 7063-70. PMID 12946150 DOI: 10.1021/jo034780g  1
2003 Harrington WR, Sheng S, Barnett DH, Petz LN, Katzenellenbogen JA, Katzenellenbogen BS. Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression. Molecular and Cellular Endocrinology. 206: 13-22. PMID 12943986 DOI: 10.1016/S0303-7207(03)00255-7  1
2003 Lee KC, Moon BS, Lee JH, Chung KH, Katzenellenbogen JA, Chi DY. Synthesis and binding affinities of fluoroalkylated raloxifenes Bioorganic and Medicinal Chemistry. 11: 3649-3658. PMID 12901910 DOI: 10.1016/S0968-0896(03)00362-6  1
2003 Dobrydneva Y, Williams RL, Katzenellenbogen JA, Ratz PH, Blackmore PF. Diethylstilbestrol and tetrahydrochrysenes are calcium channel blockers in human platelets: Relationship to the stilbene pharmacophore Thrombosis Research. 110: 23-31. PMID 12877905 DOI: 10.1016/S0049-3848(03)00110-5  1
2003 Vijaykumar D, Al-Qahtani MH, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of a fluorine-18 labeled estrogen receptor-α selective ligand: [18F] propyl pyrazole triol Nuclear Medicine and Biology. 30: 397-404. PMID 12767397 DOI: 10.1016/S0969-8051(02)00446-8  1
2003 Muthyala RS, Sheng S, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor Journal of Medicinal Chemistry. 46: 1589-1602. PMID 12699377 DOI: 10.1021/jm0204800  1
2003 Minutolo F, Antonello M, Bertini S, Rapposelli S, Rossello A, Sheng S, Carlson KE, Katzenellenbogen JA, Macchia M. Synthesis, binding affinity, and transcriptional activity of hydroxy- and methoxy-substituted 3,4-diarylsalicylaldoximes on estrogen receptors α and β Bioorganic and Medicinal Chemistry. 11: 1247-1257. PMID 12628652 DOI: 10.1016/S0968-0896(02)00640-5  1
2003 Sun J, Katzenellenbogen JA, Zhao H, Katzenellenbogen BS. DNA shuffling method for generating estrogen receptor α and β chimeras in yeast Biotechniques. 34: 278-288. PMID 12613251  1
2003 Wüst F, Carlson KE, Katzenellenbogen JA. Synthesis of novel arylpyrazolo corticosteroids as potential ligands for imaging brain glucocorticoid receptors Steroids. 68: 177-191. PMID 12606009 DOI: 10.1016/S0039-128X(02)00171-X  1
2003 Sun J, Baudry J, Katzenellenbogen JA, Katzenellenbogen BS. Molecular basis for the subtype discrimination of the estrogen receptor-β-selective ligand, diarylpropionitrile Molecular Endocrinology. 17: 247-258. PMID 12554752 DOI: 10.1210/me.2002-0341  1
2003 Bowe J, Li XF, Sugden D, Katzenellenbogen JA, Katzenellenbogen BS, O'Byrne KT. The effects of the phytoestrogen, coumestrol, on gonadotropin-releasing hormone (GnRH) mRNA expression in GT1-7 GnRH neurones Journal of Neuroendocrinology. 15: 105-108. PMID 12535152 DOI: 10.1046/j.1365-2826.2003.00991.x  1
2003 Katzenellenbogen JA, Muthyala R. Interactions of exogenous endocrine active substances with nuclear receptors Pure and Applied Chemistry. 75: 1797-1817.  1
2003 Katzenellenbogen JA, Muthyala R, Katzenellenbogen BS. Nature of the ligand-binding pocket of estrogen receptor α and β: The search for subtype-selective ligands and implications for the prediction of estrogenic activity Pure and Applied Chemistry. 75: 2397-2403.  1
2002 Tamrazi A, Carlson KE, Daniels JR, Hurth KM, Katzenellenbogen JA. Estrogen receptor dimerization: ligand binding regulates dimer affinity and dimer dissociation rate. Molecular Endocrinology (Baltimore, Md.). 16: 2706-19. PMID 12456792 DOI: 10.1210/me.2002-0250  1
2002 Harris HA, Katzenellenbogen JA, Katzenellenbogen BS. Characterization of the biological roles of the estrogen receptors, ERα and ERβ, in estrogen target tissues in vivo through the use of an ERα-selective ligand Endocrinology. 143: 4172-4177. PMID 12399409 DOI: 10.1210/en.2002-220403  1
2002 Luyt LG, Katzenellenbogen JA. A trithiolate tripodal bifunctional ligand for the radiolabeling of peptides with gallium(III) Bioconjugate Chemistry. 13: 1140-1145. PMID 12236797 DOI: 10.1021/bc025552g  1
2002 Nishiguchi GA, Rodriguez AL, Katzenellenbogen JA. Diaryl-dialkyl-substituted pyrazoles: regioselective synthesis and binding affinity for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 12: 947-50. PMID 11959000 DOI: 10.1016/S0960-894X(02)00057-4  1
2002 Shiau AK, Barstad D, Radek JT, Meyers MJ, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA, Agard DA, Greene GL. Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nature Structural Biology. 9: 359-64. PMID 11953755 DOI: 10.1038/nsb787  1
2002 Katzenellenbogen BS, Katzenellenbogen JA. Defining the "S" in SERMs Science. 295: 2380-2381. PMID 11923515 DOI: 10.1126/science.1070442  1
2002 Rickard DJ, Waters KM, Ruesink TJ, Khosla S, Katzenellenbogen JA, Katzenellenbogen BS, Riggs BL, Spelsberg TC. Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts Journal of Bone and Mineral Research. 17: 580-592. PMID 11918216  1
2002 Mull ES, Sattigeri VJ, Rodriguez AL, Katzenellenbogen JA. Aryl cyclopentadienyl tricarbonyl rhenium complexes: novel ligands for the estrogen receptor with potential use as estrogen radiopharmaceuticals. Bioorganic & Medicinal Chemistry. 10: 1381-98. PMID 11886802 DOI: 10.1016/S0968-0896(01)00406-0  1
2002 Cesati RR, Tamagnan G, Baldwin RM, Zoghbi SS, Innis RB, Kula NS, Baldessarini RJ, Katzenellenbogen JA. Synthesis of cyclopentadienyltricarbonyl rhenium phenyltropanes by double ligand transfer: organometallic ligands for the dopamine transporter. Bioconjugate Chemistry. 13: 29-39. PMID 11792176 DOI: 10.1021/bc010011x  1
2002 Vijaykumar D, Mao W, Kirschbaum KS, Katzenellenbogen JA. An efficient route for the preparation of a 21-fluoro progestin-16α,17α-dioxolane, a high-affinity ligand for PET imaging of the progesterone receptor Journal of Organic Chemistry. 67: 4904-4910. DOI: 10.1021/jo020190r  1
2002 Ghosh U, Katzenellenbogen JA. A convenient method for the preparation of highly substituted 1101 pyrimidines: Synthesis of tri- and tetra-subsituted pyrimidines from 1,3-dicarbonyl compounds and N,N,N′-tris-(trimethylsilyl)amidines Journal of Heterocyclic Chemistry. 39: 1101-1104.  1
2001 Meyers MJ, Sun J, Carlson KE, Marriner GA, Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. Journal of Medicinal Chemistry. 44: 4230-51. PMID 11708925 DOI: 10.1021/jm010254a  1
2001 Mortensen DS, Rodriguez AL, Carlson KE, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Synthesis and biological evaluation of a novel series of furans: ligands selective for estrogen receptor alpha. Journal of Medicinal Chemistry. 44: 3838-48. PMID 11689070 DOI: 10.1021/jm010211u  1
2001 Mortensen DS, Rodriguez AL, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Furans with basic side chains: synthesis and biological evaluation of a novel series of antagonists with selectivity for the estrogen receptor alpha. Bioorganic & Medicinal Chemistry Letters. 11: 2521-4. PMID 11549460 DOI: 10.1016/S0960-894X(01)00488-7  1
2001 Cesati RR, Katzenellenbogen JA. One-pot formation of substituted cyclopentadienyl and indenyltricarbonyl rhenium complexes through in situ generation of cyclopentadienyl- and indenyltributylstannanes. Journal of the American Chemical Society. 123: 4093-4. PMID 11457166 DOI: 10.1021/ja005585b  0.72
2001 Tedesco R, Youngman MK, Wilson SR, Katzenellenbogen JA. Synthesis and evaluation of hexahydrochrysene and tetrahydrobenzofluorene ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 11: 1281-4. PMID 11392537 DOI: 10.1016/S0960-894X(01)00189-5  1
2001 Tedesco R, Thomas JA, Katzenellenbogen BS, Katzenellenbogen JA. The estrogen receptor: a structure-based approach to the design of new specific hormone-receptor combinations. Chemistry & Biology. 8: 277-87. PMID 11306352 DOI: 10.1016/S1074-5521(01)00006-0  1
2001 Gee AC, Katzenellenbogen JA. Probing conformational changes in the estrogen receptor: evidence for a partially unfolded intermediate facilitating ligand binding and release. Molecular Endocrinology (Baltimore, Md.). 15: 421-8. PMID 11222743 DOI: 10.1210/mend.15.3.0602  0.96
2001 Stauffer SR, Huang Y, Coletta CJ, Tedesco R, Katzenellenbogen JA. Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor. Bioorganic & Medicinal Chemistry. 9: 141-50. PMID 11197334 DOI: 10.1016/S0968-0896(00)00228-5  0.68
2000 Stauffer SR, Coletta CJ, Tedesco R, Nishiguchi G, Carlson K, Sun J, Katzenellenbogen BS, Katzenellenbogen JA. Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. Journal of Medicinal Chemistry. 43: 4934-47. PMID 11150164 DOI: 10.1021/jm000170m  0.68
2000 Cesati RR, Katzenellenbogen JA. Preparation of hexahydrobenzo[f]isoquinolines using a vinylogous pictet-spengler cyclization. Organic Letters. 2: 3635-8. PMID 11073663  0.72
1999 Sun J, Meyers MJ, Fink BE, Rajendran R, Katzenellenbogen JA, Katzenellenbogen BS. Novel Ligands that Function as Selective Estrogens or Antiestrogens for Estrogen Receptor-α or Estrogen Receptor-β. Endocrinology. 140: 800-804. PMID 28204395 DOI: 10.1210/endo.140.2.6480  0.44
1999 Gee AC, Carlson KE, Martini PG, Katzenellenbogen BS, Katzenellenbogen JA. Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor. Molecular Endocrinology (Baltimore, Md.). 13: 1912-23. PMID 10551784 DOI: 10.1210/mend.13.11.0373  1
1999 Meyers MJ, Sun J, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes. Journal of Medicinal Chemistry. 42: 2456-68. PMID 10395487 DOI: 10.1021/jm990101b  1
1999 Fink BE, Mortensen DS, Stauffer SR, Aron ZD, Katzenellenbogen JA. Novel structural templates for estrogen-receptor ligands and prospects for combinatorial synthesis of estrogens. Chemistry & Biology. 6: 205-19. PMID 10099132 DOI: 10.1016/S1074-5521(99)80037-4  1
1999 Sun J, Meyers MJ, Fink BE, Rajendran R, Katzenellenbogen JA, Katzenellenbogen BS. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta. Endocrinology. 140: 800-4. PMID 9927308 DOI: 10.1210/endo.140.2.6480  0.44
1998 Meyers MJ, Carlson KE, Katzenellenbogen JA. Facile synthesis of high affinity styrylpyridine systems as inherently fluorescent ligands for the estrogen receptor. Bioorganic & Medicinal Chemistry Letters. 8: 3589-94. PMID 9934476 DOI: 10.1016/S0960-894X(98)00652-0  1
1993 Kym PR, Anstead GM, Pinney KG, Wilson SR, Katzenellenbogen JA. Molecular structures, conformational analysis, and preferential modes of binding of 3-aroyl-2-arylbenzo[b]thiophene estrogen receptor ligands: LY117018 and aryl azide photoaffinity labeling analogs. Journal of Medicinal Chemistry. 36: 3910-22. PMID 8254621  1
1992 Pinney KG, Carlson KE, Katzenellenbogen JA. Nonsteroidal estrogens bearing acyl azide functions: potential electrophilic and photoaffinity labeling agents for the estrogen receptor. Steroids. 57: 222-32. PMID 1488784 DOI: 10.1016/0039-128X(92)90106-J  1
1991 Pinney KG, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA. Efficient and selective photoaffinity labeling of the estrogen receptor using two nonsteroidal ligands that embody aryl azide or tetrafluoroaryl azide photoreactive functions. Biochemistry. 30: 2421-31. PMID 2001370  0.88
1990 Pomper MG, Pinney KG, Carlson KE, van Brocklin H, Mathias CJ, Welch MJ, Katzenellenbogen JA. Target tissue uptake selectivity of three fluorine-substituted progestins: potential imaging agents for receptor-positive breast tumors. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 17: 309-19. PMID 2341287 DOI: 10.1016/0883-2897(90)90058-9  1
1990 Pinney KG, Carlson KE, Katzenellenbogen JA. [3H]DU41165: a high affinity ligand and novel photoaffinity labeling reagent for the progesterone receptor. Journal of Steroid Biochemistry. 35: 179-89. PMID 2308335 DOI: 10.1016/0022-4731(90)90272-T  1
1990 Anstead GM, Peterson CS, Pinney KG, Wilson SR, Katzenellenbogen JA. Torsionally and hydrophobically modified 2,3-diarylindenes as estrogen receptor ligands. Journal of Medicinal Chemistry. 33: 2726-34. PMID 2213825  1
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