Nicole S. Sampson - Publications

Chemistry Stony Brook University, Stony Brook, NY, United States 
proteins, chemical biology, Mtb, polymers

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yuan T, Werman JM, Sampson NS. The pursuit of mechanism of action: uncovering drug complexity in TB drug discovery. Rsc Chemical Biology. 2: 423-440. PMID 33928253 DOI: 10.1039/d0cb00226g  1
2020 Bonds A, Yuan T, Werman J, Jang J, Lu R, Nesbitt NM, Garcia-Diaz M, Sampson NS. Post-translational succinylation of enoyl-CoA hydratase EchA19 slows catalytic hydration of cholesterol catabolite 3-oxo-chol-4,22-diene-24-oyl-CoA. Acs Infectious Diseases. PMID 32649175 DOI: 10.1021/Acsinfecdis.0C00329  1
2020 Gadbery J, Round J, Yuan T, Wipperman MF, Story KT, Crowe A, Casabon I, Liu J, Yang X, Eltis LD, Sampson NS. IpdE1-IpdE2 is a heterotetrameric acyl coenzyme A dehydrogenase that is widely distributed in steroid-degrading bacteria. Biochemistry. PMID 32101684 DOI: 10.1021/Acs.Biochem.0C00005  1
2019 Yuan T, Yang M, Gehring K, Sampson NS. exploits a heterohexameric enoyl-CoA hydratase retro-aldolase complex for cholesterol catabolism. Biochemistry. PMID 31568719 DOI: 10.1021/Acs.Biochem.9B00673  1
2019 Yuan T, Sampson NS. Correction to Hit Generation in TB Drug Discovery: From Genome to Granuloma. Chemical Reviews. PMID 31058490 DOI: 10.1021/Acs.Chemrev.9B00244  1
2019 Yang X, Yuan T, Ma R, Chacko K, Smith M, Deikus G, Sebra R, Kasarkskis A, van Bakel H, Franzblau SG, Sampson NS. The Mce3R stress-resistance pathway is vulnerable to small molecule targeting that improves tuberculosis drug activities. Acs Infectious Diseases. PMID 31012313 DOI: 10.1021/Acsinfecdis.9B00099  1
2018 Li G, Sampson NS. Alternating Ring-Opening Metathesis Polymerization (AROMP) of Hydrophobic and Hydrophilic Monomers Provides Oligomers with Side-Chain Sequence Control. Macromolecules. 51: 3932-3940. PMID 30524145 DOI: 10.1021/Acs.Macromol.8B00562  1
2018 Zhang J, Li G, Sampson NS. Incorporation of Large Cycloalkene Rings into Alternating Copolymers Allows Control of Glass Transition and Hydrophobicity. Acs Macro Letters. 7: 1068-1072. PMID 30271676 DOI: 10.1021/Acsmacrolett.8B00510  1
2018 Bonds AC, Sampson NS. More than cholesterol catabolism: regulatory vulnerabilities in Mycobacterium tuberculosis. Current Opinion in Chemical Biology. 44: 39-46. PMID 29906645 DOI: 10.1016/J.Cbpa.2018.05.012  0.6
2018 Wands AM, Cervin J, Huang H, Zhang Y, Youn G, Brautigam CA, Matson Dzebo M, Bjorklund P, Wallenius V, Bright DK, Bennett CS, Wittung-Stafshede P, Sampson NS, Yrlid U, Kohler JJ. Fucosylated molecules competitively interfere with cholera toxin binding to host cells. Acs Infectious Diseases. PMID 29411974 DOI: 10.1021/Acsinfecdis.7B00085  0.72
2018 Yuan T, Sampson NS. Hit Generation in TB Drug Discovery: From Genome to Granuloma. Chemical Reviews. PMID 29384369 DOI: 10.1021/Acs.Chemrev.7B00602  1
2017 Alford VM, Kamath A, Ren X, Kumar K, Gan Q, Awwa M, Tong M, Seeliger MA, Cao J, Ojima I, Sampson NS. Targeting the Hemopexin-like Domain of Latent Matrix Metalloproteinase-9 (proMMP-9) with a Small Molecule Inhibitor Prevents the Formation of Focal Adhesion Junctions. Acs Chemical Biology. PMID 28945333 DOI: 10.1021/Acschembio.7B00758  0.68
2017 Huang H, Rodolis MT, Bhatia SR, Sampson NS. Sugars require rigid multivalent displays for activation of mouse sperm acrosomal exocytosis. Biochemistry. PMID 28509550 DOI: 10.1021/Acs.Biochem.7B00166  0.8
2016 Ueki N, Wang W, Swenson C, McNaughton C, Sampson NS, Hayman MJ. Synthesis and Preclinical Evaluation of a Highly Improved Anticancer Prodrug Activated by Histone Deacetylases and Cathepsin L. Theranostics. 6: 808-16. PMID 27162551 DOI: 10.7150/Thno.13826  1
2016 Rodolis MT, Huang H, Sampson NS. Glycopolymer induction of mouse sperm acrosomal exocytosis shows highly cooperative self-antagonism. Biochemical and Biophysical Research Communications. PMID 27150629 DOI: 10.1016/J.Bbrc.2016.05.003  1
2016 Parker KA, Sampson NS. Precision Synthesis of Alternating Copolymers via Ring-Opening Polymerization of 1-Substituted Cyclobutenes. Accounts of Chemical Research. PMID 26914522 DOI: 10.1021/Acs.Accounts.5B00490  1
2015 Lu R, Schmitz W, Sampson NS. α-Methyl Acyl CoA Racemase Provides Mycobacterium tuberculosis Catabolic Access to Cholesterol Esters. Biochemistry. 54: 5669-72. PMID 26348625 DOI: 10.1021/Acs.Biochem.5B00911  1
2015 Touchette MH, Bommineni GR, Delle Bovi RJ, Gadbery JE, Nicora CD, Shukla AK, Kyle JE, Metz TO, Martin DW, Sampson NS, Miller WT, Tonge PJ, Seeliger JC. Diacyltransferase Activity and Chain Length Specificity of Mycobacterium tuberculosis PapA5 in the Synthesis of Alkyl β-Diol Lipids. Biochemistry. 54: 5457-68. PMID 26271001 DOI: 10.1021/Acs.Biochem.5B00455  1
2015 Tan L, Li G, Parker KA, Sampson NS. Ru-Catalyzed Isomerization Provides Access to Alternating Copolymers via Ring-Opening Metathesis Polymerization. Macromolecules. 48: 4793-4800. PMID 26243969 DOI: 10.1021/Acs.Macromol.5B01058  1
2015 Yang M, Lu R, Guja KE, Wipperman MF, St Clair JR, Bonds AC, Garcia-Diaz M, Sampson NS. Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA. Acs Infectious Diseases. 1: 110-125. PMID 26161441 DOI: 10.1021/Id500033M  1
2015 Lee S, Wang W, Lee Y, Sampson NS. Cyclic acetals as cleavable linkers for affinity capture. Organic & Biomolecular Chemistry. PMID 26152933 DOI: 10.1039/C5Ob01056J  1
2015 Schaefer CM, Lu R, Nesbitt NM, Schiebel J, Sampson NS, Kisker C. FadA5 a thiolase from Mycobacterium tuberculosis: a steroid-binding pocket reveals the potential for drug development against tuberculosis. Structure (London, England : 1993). 23: 21-33. PMID 25482540 DOI: 10.1016/J.Str.2014.10.010  1
2014 Tan L, Parker KA, Sampson NS. A Bicyclo[4.2.0]octene-Derived Monomer Provides Completely Linear Alternating Copolymers via Alternating Ring-Opening Metathesis Polymerization (AROMP). Macromolecules. 47: 6572-6579. PMID 25328246 DOI: 10.1021/Ma5012039  1
2014 Yang M, Guja KE, Thomas ST, Garcia-Diaz M, Sampson NS. A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis. Acs Chemical Biology. 9: 2632-45. PMID 25203216 DOI: 10.1021/Cb500232H  1
2014 Wipperman MF, Sampson NS, Thomas ST. Pathogen roid rage: cholesterol utilization by Mycobacterium tuberculosis. Critical Reviews in Biochemistry and Molecular Biology. 49: 269-93. PMID 24611808 DOI: 10.3109/10409238.2014.895700  1
2014 Gao J, Sampson NS. A GMC oxidoreductase homologue is required for acetylation of glycopeptidolipid in Mycobacterium smegmatis. Biochemistry. 53: 611-3. PMID 24444367 DOI: 10.1021/Bi4015083  1
2014 Wu L, Sampson NS. Fucose, mannose, and β-N-acetylglucosamine glycopolymers initiate the mouse sperm acrosome reaction through convergent signaling pathways. Acs Chemical Biology. 9: 468-75. PMID 24252131 DOI: 10.1021/Cb400550J  1
2013 Evensen NA, Li J, Yang J, Yu X, Sampson NS, Zucker S, Cao J. Development of a high-throughput three-dimensional invasion assay for anti-cancer drug discovery. Plos One. 8: e82811. PMID 24349367 DOI: 10.1371/Journal.Pone.0082811  1
2013 Ueki N, Lee S, Sampson NS, Hayman MJ. Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease. Nature Communications. 4: 2735. PMID 24193185 DOI: 10.1038/Ncomms3735  1
2013 Romulus J, Tan L, Weck M, Sampson NS. Alternating ROMP copolymers containing charge-transfer units. Acs Macro Letters. 2: 749-752. PMID 24159424 DOI: 10.1021/Mz4002673  1
2013 Wipperman MF, Yang M, Thomas ST, Sampson NS. Shrinking the FadE proteome of Mycobacterium tuberculosis: insights into cholesterol metabolism through identification of an α2β2 heterotetrameric acyl coenzyme A dehydrogenase family. Journal of Bacteriology. 195: 4331-41. PMID 23836861 DOI: 10.1128/Jb.00502-13  1
2013 Su CY, London E, Sampson NS. Mapping peptide thiol accessibility in membranes using a quaternary ammonium isotope-coded mass tag (ICMT). Bioconjugate Chemistry. 24: 1235-47. PMID 23725486 DOI: 10.1021/Bc400171J  1
2013 Thomas ST, Sampson NS. Mycobacterium tuberculosis utilizes a unique heterotetrameric structure for dehydrogenation of the cholesterol side chain. Biochemistry. 52: 2895-904. PMID 23560677 DOI: 10.1021/Bi4002979  1
2013 Slayden RA, Jackson M, Zucker J, Ramirez MV, Dawson CC, Crew R, Sampson NS, Thomas ST, Jamshidi N, Sisk P, Caspi R, Crick DC, McNeil MR, Pavelka MS, Niederweis M, et al. Updating and curating metabolic pathways of TB. Tuberculosis (Edinburgh, Scotland). 93: 47-59. PMID 23375378 DOI: 10.1016/J.Tube.2012.11.001  1
2011 Thomas ST, VanderVen BC, Sherman DR, Russell DG, Sampson NS. Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism. The Journal of Biological Chemistry. 286: 43668-78. PMID 22045806 DOI: 10.1074/Jbc.M111.313643  1
2011 Zarrabi K, Dufour A, Li J, Kuscu C, Pulkoski-Gross A, Zhi J, Hu Y, Sampson NS, Zucker S, Cao J. Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration. The Journal of Biological Chemistry. 286: 33167-77. PMID 21795678 DOI: 10.1074/Jbc.M111.256644  1
2011 Dufour A, Sampson NS, Li J, Kuscu C, Rizzo RC, Deleon JL, Zhi J, Jaber N, Liu E, Zucker S, Cao J. Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Research. 71: 4977-88. PMID 21646471 DOI: 10.1158/0008-5472.Can-10-4552  1
2011 Thomas ST, Yang X, Sampson NS. Inhibition of the M. tuberculosis 3β-hydroxysteroid dehydrogenase by azasteroids. Bioorganic & Medicinal Chemistry Letters. 21: 2216-9. PMID 21439822 DOI: 10.1016/J.Bmcl.2011.03.004  1
2011 Song A, Walker SG, Parker KA, Sampson NS. Antibacterial studies of cationic polymers with alternating, random, and uniform backbones. Acs Chemical Biology. 6: 590-9. PMID 21370918 DOI: 10.1021/Cb100413W  1
2011 Yang X, Gao J, Smith I, Dubnau E, Sampson NS. Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection. Journal of Bacteriology. 193: 1473-6. PMID 21257778 DOI: 10.1128/Jb.01210-10  1
2010 Dufour A, Zucker S, Sampson NS, Kuscu C, Cao J. Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides. The Journal of Biological Chemistry. 285: 35944-56. PMID 20837483 DOI: 10.1074/Jbc.M109.091769  1
2010 Song A, Parker KA, Sampson NS. Cyclic alternating ring-opening metathesis polymerization (CAROMP). Rapid access to functionalized cyclic polymers. Organic Letters. 12: 3729-31. PMID 20684538 DOI: 10.1021/Ol101432M  1
2010 Song A, Lee JC, Parker KA, Sampson NS. Scope of the ring-opening metathesis polymerization (ROMP) reaction of 1-substituted cyclobutenes. Journal of the American Chemical Society. 132: 10513-20. PMID 20614908 DOI: 10.1021/Ja1037098  1
2010 Nesbitt NM, Yang X, Fontán P, Kolesnikova I, Smith I, Sampson NS, Dubnau E. A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol. Infection and Immunity. 78: 275-82. PMID 19822655 DOI: 10.1128/Iai.00893-09  1
2010 Dufour A, Sampson NS, Kuscu C, Zucker S, Cao J. Abstract 533: Critical role of MMP-9 dimers in cell migration: design of inhibitory peptides Cancer Research. 70: 533-533. DOI: 10.1158/1538-7445.Am10-533  0.68
2009 Lyubimov AY, Chen L, Sampson NS, Vrielink A. A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase. Acta Crystallographica. Section D, Biological Crystallography. 65: 1222-31. PMID 19923719 DOI: 10.1107/S0907444909037421  1
2009 Kreit J, Sampson NS. Cholesterol oxidase: physiological functions. The Febs Journal. 276: 6844-56. PMID 19843168 DOI: 10.1111/J.1742-4658.2009.07378.X  1
2009 Yang X, Nesbitt NM, Dubnau E, Smith I, Sampson NS. Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. Biochemistry. 48: 3819-21. PMID 19364125 DOI: 10.1021/Bi9005418  1
2009 Baessler KA, Lee Y, Sampson NS. Beta1 integrin is an adhesion protein for sperm binding to eggs. Acs Chemical Biology. 4: 357-66. PMID 19338281 DOI: 10.1021/Cb900013D  1
2009 Song A, Parker KA, Sampson NS. Synthesis of copolymers by alternating ROMP (AROMP). Journal of the American Chemical Society. 131: 3444-5. PMID 19275253 DOI: 10.1021/Ja809661K  1
2009 Lee Y, Sampson NS. Polymeric ADAM protein mimics interrogate mammalian sperm-egg binding. Chembiochem : a European Journal of Chemical Biology. 10: 929-37. PMID 19229908 DOI: 10.1002/Cbic.200800791  1
2008 Dufour A, Sampson NS, Zucker S, Cao J. Role of the hemopexin domain of matrix metalloproteinases in cell migration. Journal of Cellular Physiology. 217: 643-51. PMID 18636552 DOI: 10.1002/Jcp.21535  1
2008 Chen L, Lyubimov AY, Brammer L, Vrielink A, Sampson NS. The binding and release of oxygen and hydrogen peroxide are directed by a hydrophobic tunnel in cholesterol oxidase. Biochemistry. 47: 5368-77. PMID 18410129 DOI: 10.1021/Bi800228W  1
2007 Lyubimov AY, Heard K, Tang H, Sampson NS, Vrielink A. Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase. Protein Science : a Publication of the Protein Society. 16: 2647-56. PMID 18029419 DOI: 10.1110/Ps.073168207  1
2007 Yang X, Dubnau E, Smith I, Sampson NS. Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase. Biochemistry. 46: 9058-67. PMID 17630785 DOI: 10.1021/Bi700688X  1
2007 Nesbitt NM, Sampson NS. Antifungal tradecraft by cholesterol oxidase. Chemistry & Biology. 14: 238-41. PMID 17379137 DOI: 10.1016/J.Chembiol.2007.03.003  1
2007 Kempf JG, Jung JY, Ragain C, Sampson NS, Loria JP. Dynamic requirements for a functional protein hinge. Journal of Molecular Biology. 368: 131-49. PMID 17336327 DOI: 10.1016/J.Jmb.2007.01.074  1
2006 Lee Y, Sampson NS. Romping the cellular landscape: linear scaffolds for molecular recognition. Current Opinion in Structural Biology. 16: 544-50. PMID 16781140 DOI: 10.1016/J.Sbi.2006.05.015  1
2006 Baessler KA, Lee Y, Roberts KS, Facompre N, Sampson NS. Multivalent fertilinbeta oligopeptides: the dependence of fertilization inhibition on length and density. Chemistry & Biology. 13: 251-9. PMID 16638530 DOI: 10.1016/J.Chembiol.2005.12.010  1
2006 Lee JC, Parker KA, Sampson NS. Amino acid-bearing ROMP polymers with a stereoregular backbone. Journal of the American Chemical Society. 128: 4578-9. PMID 16594687 DOI: 10.1021/Ja058801V  1
2004 Roberts KS, Sampson NS. A facile synthetic method to prepare fluorescently labeled ROMP polymers. Organic Letters. 6: 3253-5. PMID 15355025 DOI: 10.1021/Ol048935Y  1
2004 Xiang J, Jung JY, Sampson NS. Entropy effects on protein hinges: the reaction catalyzed by triosephosphate isomerase. Biochemistry. 43: 11436-45. PMID 15350130 DOI: 10.1021/Bi049208D  1
2004 Kursula I, Salin M, Sun J, Norledge BV, Haapalainen AM, Sampson NS, Wierenga RK. Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase. Protein Engineering, Design & Selection : Peds. 17: 375-82. PMID 15166315 DOI: 10.1093/Protein/Gzh048  1
2004 Xiang J, Sampson NS. Library screening studies to investigate substrate specificity in the reaction catalyzed by cholesterol oxidase. Protein Engineering, Design & Selection : Peds. 17: 341-8. PMID 15136716 DOI: 10.1093/Protein/Gzh041  1
2004 Konkar S, Gupta S, Sampson NS. Fertilin beta peptidic liposomes inhibit fertilization by steric blockage. Bioorganic & Medicinal Chemistry Letters. 14: 1381-4. PMID 15006366 DOI: 10.1016/J.Bmcl.2003.09.097  1
2004 Ahn KW, Sampson NS. Cholesterol oxidase senses subtle changes in lipid bilayer structure. Biochemistry. 43: 827-36. PMID 14730988 DOI: 10.1021/Bi035697Q  1
2003 Vrielink A, Sampson N. Sub-Ångstrom resolution enzyme X-ray structures: Is seeing believing? Current Opinion in Structural Biology. 13: 709-715. PMID 14675549 DOI: 10.1016/J.Sbi.2003.10.012  1
2003 Roberts KS, Konkar S, Sampson NS. Comparison of fertilinbeta-peptide-substituted polymers and liposomes as inhibitors of in vitro fertilization. Chembiochem : a European Journal of Chemical Biology. 4: 1229-31. PMID 14613117 DOI: 10.1002/Cbic.200300672  1
2003 Kempf JG, Jung JY, Sampson NS, Loria JP. Off-resonance TROSY (R1 rho - R1) for quantitation of fast exchange processes in large proteins. Journal of the American Chemical Society. 125: 12064-5. PMID 14518971 DOI: 10.1021/Ja037101S  1
2003 Sampson NS, Vrielink A. Cholesterol oxidases: a study of nature's approach to protein design. Accounts of Chemical Research. 36: 713-22. PMID 12974654 DOI: 10.1021/Ar9800587  1
2003 Roberts KS, Sampson NS. Increased polymer length of oligopeptide-substituted polynorbornenes with LiCl. The Journal of Organic Chemistry. 68: 2020-3. PMID 12608828 DOI: 10.1021/Jo0265737  1
2003 Lario PI, Sampson N, Vrielink A. Sub-atomic resolution crystal structure of cholesterol oxidase: What atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity Journal of Molecular Biology. 326: 1635-1650. PMID 12595270 DOI: 10.1016/S0022-2836(03)00054-8  1
2002 Yin Y, Liu P, Anderson RG, Sampson NS. Construction of a catalytically inactive cholesterol oxidase mutant: investigation of the interplay between active site-residues glutamate 361 and histidine 447. Archives of Biochemistry and Biophysics. 402: 235-42. PMID 12051668 DOI: 10.1016/S0003-9861(02)00081-4  1
2002 Li H, Sampson N. Structural analysis of fertilinβ cyclic peptide mimics that are ligands for α6β1 integrin Journal of Peptide Research. 59: 45-54. PMID 11906606  1
2001 Sampson NS. Dissection of a flavoenzyme active site: the reaction catalyzed by cholesterol oxidase. Antioxidants & Redox Signaling. 3: 839-46. PMID 11761331 DOI: 10.1089/15230860152665019  1
2001 Yin Y, Sampson NS, Vrielink A, Lario PI. The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase. Biochemistry. 40: 13779-87. PMID 11705367 DOI: 10.1021/Bi010843I  1
2001 Sampson NS, Mrksich M, Bertozzi CR. Surface molecular recognition. Proceedings of the National Academy of Sciences of the United States of America. 98: 12870-1. PMID 11687628 DOI: 10.1073/Pnas.231391398  1
2001 Gupta S, Sampson NS. Dimyristoylated peptides incorporated into liposomes are polyvalent fertilin beta mimics. Organic Letters. 3: 3333-5. PMID 11594827 DOI: 10.1021/Ol016573D  1
2001 Sampson NS, Ryan ST, Enke DA, Cosgrove D, Koteliansky V, Gotwals P. Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis. The Journal of Biological Chemistry. 276: 34182-8. PMID 11447218 DOI: 10.1074/jbc.M102859200  1
2001 Xiang J, Sun J, Sampson NS. The importance of hinge sequence for loop function and catalytic activity in the reaction catalyzed by triosephosphate isomerase. Journal of Molecular Biology. 307: 1103-12. PMID 11286559 DOI: 10.1006/Jmbi.2001.4536  1
2001 Gupta S, Sampson NS. Dimyristoylated peptides incorporated into liposomes are polyvalent fertilin β mimics Organic Letters. 3: 3333-3335. DOI: 10.1021/ol016573d  1
2000 Chen X, Wolfgang DE, Sampson NS. Use of the parallax-quench method to determine the position of the active-site loop of cholesterol oxidase in lipid bilayers. Biochemistry. 39: 13383-9. PMID 11063575 DOI: 10.1021/Bi001407J  1
2000 Gupta S, Li H, Sampson NS. Characterization of fertilin beta-disintegrin binding specificity in sperm-egg adhesion. Bioorganic & Medicinal Chemistry. 8: 723-9. PMID 10819161 DOI: 10.1016/S0968-0896(00)00005-5  1
2000 McCann AE, Sampson NS. A C6-flavin adduct is the major product of irreversible inactivation of cholesterol oxidase by 2α,3α-cyclopropano-5α-cholestan-3β-ol Journal of the American Chemical Society. 122: 35-39. DOI: 10.1021/Ja992053Q  1
1999 Sun J, Sampson NS. Understanding protein lids: kinetic analysis of active hinge mutants in triosephosphate isomerase. Biochemistry. 38: 11474-81. PMID 10471299 DOI: 10.1021/Bi990862G  1
1999 Yue QK, Kass IJ, Sampson NS, Vrielink A. Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants. Biochemistry. 38: 4277-86. PMID 10194345 DOI: 10.1021/Bi982497J  1
1999 Chen H, Sampson NS. Mediation of sperm-egg fusion: evidence that mouse egg alpha6beta1 integrin is the receptor for sperm fertilinbeta. Chemistry & Biology. 6: 1-10. PMID 9889149 DOI: 10.1016/S1074-5521(99)80015-5  1
1998 Chen H, Pyluck AL, Janik M, Sampson NS. Peptides corresponding to the epidermal growth factor-like domain of mouse fertilin: synthesis and biological activity. Biopolymers. 47: 299-307. PMID 10036971 DOI: 10.1002/(Sici)1097-0282(1998)47:4<299::Aid-Bip5>3.0.Co;2-X  1
1998 Kass IJ, Sampson NS. Evaluation of the role of His447 in the reaction catalyzed by cholesterol oxidase. Biochemistry. 37: 17990-8000. PMID 9922167 DOI: 10.1021/Bi982115+  1
1998 Kass IJ, Sampson NS. The importance of GLU361 position in the reaction catalyzed by cholesterol oxidase. Bioorganic & Medicinal Chemistry Letters. 8: 2663-8. PMID 9873599 DOI: 10.1016/S0960-894X(98)00478-8  1
1998 Sun J, Sampson NS. Determination of the amino acid requirements for a protein hinge in triosephosphate isomerase. Protein Science : a Publication of the Protein Society. 7: 1495-505. PMID 9684881 DOI: 10.1002/Pro.5560070702  1
1998 Sampson NS, Kass IJ, Ghoshroy KB. Assessment of the role of an omega loop of cholesterol oxidase: a truncated loop mutant has altered substrate specificity. Biochemistry. 37: 5770-8. PMID 9548964 DOI: 10.1021/Bi973067G  1
1998 Sampson NS, Chen X. Increased expression of Brevibacterium sterolicum cholesterol oxidase in Escherichia coli by genetic modification. Protein Expression and Purification. 12: 347-52. PMID 9535702 DOI: 10.1006/Prep.1997.0855  1
1997 Ghoshroy KB, Zhu W, Sampson NS. Investigation of membrane disruption in the reaction catalyzed by cholesterol oxidase. Biochemistry. 36: 6133-40. PMID 9166784 DOI: 10.1021/Bi962190P  1
1997 Sampson NS, McCann AE. 4,5-Cyclopropanocholestan-3β-ol Substrates for Cholesterol Oxidase and Their 1H NMR Assignments Journal of Organic Chemistry. 62: 5893-5897. DOI: 10.1021/Jo9706537  1
1997 Sampson NS, Kass IJ. Isomerization, but not oxidation, is suppressed by a single point mutation, E361Q, in the reaction catalyzed by cholesterol oxidase Journal of the American Chemical Society. 119: 855-862. DOI: 10.1021/Ja962258O  1
1997 Pyluck A, Yuan R, Galligan E, Primakoff P, Myles DG, Sampson NS. ECD peptides inhibit in vitro fertilization in mice Bioorganic and Medicinal Chemistry Letters. 7: 1053-1058. DOI: 10.1016/S0960-894X(97)00160-1  1
1995 Kass IJ, Sampson NS. The isomerization catalyzed by Brevibacterium sterolicum cholesterol oxidase proceeds stereospecifically with one base. Biochemical and Biophysical Research Communications. 206: 688-93. PMID 7826388 DOI: 10.1006/Bbrc.1995.1097  1
1992 Sampson NS, Knowles JR. Segmental motion in catalysis: investigation of a hydrogen bond critical for loop closure in the reaction of triosephosphate isomerase. Biochemistry. 31: 8488-94. PMID 1390633 DOI: 10.1021/Bi00151A015  1
1992 Sampson NS, Knowles JR. Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomerase. Biochemistry. 31: 8482-7. PMID 1390632 DOI: 10.1021/Bi00151A014  1
1991 Bone R, Sampson NS, Bartlett PA, Agard DA. Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. Biochemistry. 30: 2263-72. PMID 1998685 DOI: 10.1021/Bi00222A032  1
1991 Sampson NS, Bartlett PA. Peptidic phosphonylating agents as irreversible inhibitors of serine proteases and models of the tetrahedral intermediates. Biochemistry. 30: 2255-63. PMID 1998684 DOI: 10.1021/Bi00222A031  1
1991 Sampson NS, Bartlett PA. Attempted de novo design, synthesis, and evaluation of a ligand for the allosteric site of phosphofructokinase Journal of Organic Chemistry. 56: 7179-7183. DOI: 10.1021/Jo00025A044  1
1988 Sampson NS, Bartlett PA. Synthesis of phosphonic acid derivatives by oxidative activation of phosphinate esters Journal of Organic Chemistry. 53: 4500-4503. DOI: 10.1021/Jo00254A015  1
1987 Romoff TT, Sampson NS, Van Eikeren P. Regioselectivity and kinetics of hydride transfer in substituted 1-benzyl-3-quinolinecarboxamide redox reactions Journal of Organic Chemistry. 52: 4454-4459. DOI: 10.1021/Jo00229A005  1
Show low-probability matches.