| Year |
Citation |
Score |
| 2024 |
Zhu L, Deng F, Bai D, Hou J, Jia Q, Zhang C, Ou K, Li S, Li XJ, Yin P. Loss of TDP-43 mediates severe neurotoxicity by suppressing PJA1 gene transcription in the monkey brain. Cellular and Molecular Life Sciences : Cmls. 81: 16. PMID 38194085 DOI: 10.1007/s00018-023-05066-2 |
0.324 |
|
| 2023 |
Tong H, Yang T, Liu L, Li C, Sun Y, Jia Q, Qin Y, Chen L, Zhao X, Zhou G, Yan S, Li XJ, Li S. Aberrant splicing of mutant huntingtin in Huntington's disease knock-in pigs. Neurobiology of Disease. 187: 106291. PMID 37716514 DOI: 10.1016/j.nbd.2023.106291 |
0.408 |
|
| 2023 |
Li C, Lin Y, Chen Y, Song X, Zheng X, Li J, He J, Chen X, Huang C, Wang W, Wu J, Wu J, Gao J, Tu Z, Li XJ, et al. A Specific Mini-Intrabody Mediates Lysosome Degradation of Mutant Huntingtin. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2301120. PMID 37688357 DOI: 10.1002/advs.202301120 |
0.425 |
|
| 2023 |
Liu L, Tong H, Sun Y, Chen X, Yang T, Zhou G, Li XJ, Li S. Huntingtin Interacting Proteins and Pathological Implications. International Journal of Molecular Sciences. 24. PMID 37685866 DOI: 10.3390/ijms241713060 |
0.323 |
|
| 2023 |
Pan Y, Tang B, Li XJ, Li S, Liu Q. Rhes depletion promotes striatal accumulation and aggregation of mutant huntingtin in a presymptomatic HD mouse model. Frontiers in Aging Neuroscience. 15: 1237018. PMID 37637962 DOI: 10.3389/fnagi.2023.1237018 |
0.358 |
|
| 2023 |
Yang S, Ma J, Zhang H, Chen L, Li Y, Pan M, Zhu H, Liang J, He D, Li S, Li XJ, Guo X. Mutant HTT does not affect glial development but impairs myelination in the early disease stage. Frontiers in Neuroscience. 17: 1238306. PMID 37539389 DOI: 10.3389/fnins.2023.1238306 |
0.379 |
|
| 2023 |
Bai D, Zhu L, Jia Q, Duan X, Chen L, Wang X, Hou J, Jiang G, Yang S, Li S, Li XJ, Yin P. Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington's disease knock-in mice. Progress in Neurobiology. 227: 102484. PMID 37315918 DOI: 10.1016/j.pneurobio.2023.102484 |
0.34 |
|
| 2023 |
Yan S, Zheng X, Lin Y, Li C, Liu Z, Li J, Tu Z, Zhao Y, Huang C, Chen Y, Li J, Song X, Han B, Wang W, Liang W, ... ... Li XJ, et al. Cas9-mediated replacement of expanded CAG repeats in a pig model of Huntington's disease. Nature Biomedical Engineering. PMID 36797418 DOI: 10.1038/s41551-023-01007-3 |
0.311 |
|
| 2022 |
Jia Q, Li S, Li XJ, Yin P. Neuroinflammation in Huntington's disease: From animal models to clinical therapeutics. Frontiers in Immunology. 13: 1088124. PMID 36618375 DOI: 10.3389/fimmu.2022.1088124 |
0.33 |
|
| 2022 |
Zhao X, Sun Y, Wang Z, Chen L, Li S, Li XJ. Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice. Frontiers in Cellular Neuroscience. 16: 1021592. PMID 36439204 DOI: 10.3389/fncel.2022.1021592 |
0.369 |
|
| 2022 |
Chen X, Sun Y, Chen L, Chen XS, Pan M, Zhang Y, Wang Q, Yang W, Yin P, He D, Guo X, Yang S, Zeng Y, Yan S, Li XJ, et al. Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains. Cellular and Molecular Life Sciences : Cmls. 79: 554. PMID 36251080 DOI: 10.1007/s00018-022-04577-8 |
0.425 |
|
| 2021 |
Yin P, Bai D, Deng F, Zhang C, Jia Q, Zhu L, Chen L, Li B, Guo X, Ye J, Tan Z, Wang L, Li S, Li XJ. SQSTM1-mediated clearance of cytoplasmic mutant TARDBP/TDP-43 in the monkey brain. Autophagy. 1-14. PMID 34936539 DOI: 10.1080/15548627.2021.2013653 |
0.33 |
|
| 2021 |
Yang W, Guo X, Tu Z, Chen X, Han R, Liu Y, Yan S, Wang Q, Wang Z, Zhao X, Zhang Y, Xiong X, Yang H, Yin P, Wan H, ... ... Li XJ, et al. PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis. Protein & Cell. PMID 34800266 DOI: 10.1007/s13238-021-00888-x |
0.305 |
|
| 2021 |
Yin P, Bai D, Zhu L, Deng F, Guo X, Li B, Chen L, Li S, Li XJ. Cytoplasmic TDP-43 impairs the activity of the ubiquitin-proteasome system. Experimental Neurology. 113833. PMID 34363810 DOI: 10.1016/j.expneurol.2021.113833 |
0.358 |
|
| 2021 |
Jing L, Cheng S, Pan Y, Liu Q, Yang W, Li S, Li XJ. Accumulation of Endogenous Mutant Huntingtin in Astrocytes Exacerbates Neuropathology of Huntington Disease in Mice. Molecular Neurobiology. PMID 34250577 DOI: 10.1007/s12035-021-02451-5 |
0.475 |
|
| 2021 |
Bai D, Yin P, Zhang Y, Sun F, Chen L, Lin L, Yan S, Li S, Li XJ. Lack of association of somatic CAG repeat expansion with striatal neurodegeneration in HD knock-in animal models. Human Molecular Genetics. PMID 33949657 DOI: 10.1093/hmg/ddab129 |
0.355 |
|
| 2021 |
Zhang XY, Li J, Li CJ, Lin YQ, Huang CH, Zheng X, Song XC, Tu ZC, Li XJ, Yan S. Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey. Neural Regeneration Research. 16: 2446-2452. PMID 33907033 DOI: 10.4103/1673-5374.313056 |
0.302 |
|
| 2020 |
Liu Q, Cheng S, Yang H, Zhu L, Pan Y, Jing L, Tang B, Li S, Li XJ. Loss of Hap1 selectively promotes striatal degeneration in Huntington disease mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747555 DOI: 10.1073/Pnas.2002283117 |
0.559 |
|
| 2020 |
Chen X, Xin N, Pan Y, Zhu L, Yin P, Liu Q, Yang W, Xu X, Li S, Li XJ. Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response. Frontiers in Cellular Neuroscience. 14: 125. PMID 32581713 DOI: 10.3389/Fncel.2020.00125 |
0.446 |
|
| 2020 |
Yang H, Yang S, Jing L, Huang L, Chen L, Zhao X, Yang W, Pan Y, Yin P, Qin ZS, Li S, Li XJ. Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form. Nature Communications. 11: 2582. PMID 32444599 DOI: 10.1038/S41467-020-16318-1 |
0.546 |
|
| 2020 |
Yin P, Liu Q, Pan Y, Yang W, Yang S, Wei W, Chen X, Hong Y, Bai D, Li XJ, Li S. Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease. Embo Reports. e49783. PMID 32270922 DOI: 10.15252/Embr.201949783 |
0.426 |
|
| 2020 |
Liu Q, Huang S, Yin P, Yang S, Zhang J, Jing L, Cheng S, Tang B, Li XJ, Pan Y, Li S. Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17. Nature Communications. 11: 1101. PMID 32107387 DOI: 10.1038/S41467-020-14931-8 |
0.526 |
|
| 2020 |
Yang S, Yang H, Huang L, Chen L, Qin Z, Li S, Li XJ. Lack of RAN-mediated toxicity in Huntington's disease knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32029588 DOI: 10.1073/Pnas.1919197117 |
0.434 |
|
| 2019 |
Pan Y, Liu Q, Zhang J, Yang Y, Tian Y, Zeng J, Yin P, Mei L, Xiong WC, Li XJ, Li S, Tang B. PRRT2 frameshift mutation reduces its mRNA stability resulting loss of function in paroxysmal kinesigenic dyskinesia. Biochemical and Biophysical Research Communications. PMID 31785815 DOI: 10.1016/J.Bbrc.2019.11.025 |
0.374 |
|
| 2019 |
Liu Q, Pan Y, Li XJ, Li S. Molecular Mechanisms and Therapeutics for SCA17. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31317427 DOI: 10.1007/S13311-019-00762-Z |
0.478 |
|
| 2019 |
Yan S, Li S, Li XJ. Use of large animal models to investigate Huntington's diseases. Cell Regeneration (London, England). 8: 9-11. PMID 31205683 DOI: 10.1016/J.Cr.2019.01.001 |
0.39 |
|
| 2019 |
Ting LL, Lu HT, Yen SF, Ngo TH, Tu FY, Tsai IS, Tsai YH, Chang FY, Li XJ, Li S, Lee CK, Kao SH, Kuo YM, Lin YF. Expression of AHI1 Rescues Amyloidogenic Pathology in Alzheimer's Disease Model Cells. Molecular Neurobiology. PMID 31062249 DOI: 10.1007/S12035-019-1587-1 |
0.368 |
|
| 2019 |
Yang W, Li S, Li XJ. A CRISPR monkey model unravels a unique function of PINK1 in primate brains. Molecular Neurodegeneration. 14: 17. PMID 31046796 DOI: 10.1186/S13024-019-0321-9 |
0.384 |
|
| 2019 |
Zhu L, Chen L, Yan L, Perkins BD, Li S, Li B, Xu HA, Li XJ. Mutant Ahi1 Affects Retinal Axon Projection in Zebrafish Toxic Gain of Function. Frontiers in Cellular Neuroscience. 13: 81. PMID 30949029 DOI: 10.3389/Fncel.2019.00081 |
0.335 |
|
| 2019 |
Yin P, Guo X, Yang W, Yan S, Yang S, Zhao T, Sun Q, Liu Y, Li S, Li XJ. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathologica. PMID 30810811 DOI: 10.1007/S00401-019-01979-0 |
0.429 |
|
| 2019 |
Yang W, Liu Y, Tu Z, Xiao C, Yan S, Ma X, Guo X, Chen X, Yin P, Yang Z, Yang S, Jiang T, Li S, Qin C, Li XJ. CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys. Cell Research. PMID 30770867 DOI: 10.1038/S41422-019-0142-Y |
0.334 |
|
| 2019 |
Huang S, Zhu S, Li XJ, Li S. The Expanding Clinical Universe of Polyglutamine Disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858418822993. PMID 30614396 DOI: 10.1177/1073858418822993 |
0.393 |
|
| 2018 |
Li T, Li S, Gao X, Cai Q, Li XJ. Expression and Localization of Huntingtin-Associated Protein 1 (HAP1) in the Human Digestive System. Digestive Diseases and Sciences. PMID 30560333 DOI: 10.1007/S10620-018-5425-5 |
0.459 |
|
| 2018 |
Yang S, Li S, Li XJ. MANF: A New Player in the Control of Energy Homeostasis, and Beyond. Frontiers in Physiology. 9: 1725. PMID 30555354 DOI: 10.3389/Fphys.2018.01725 |
0.369 |
|
| 2018 |
Yang S, Li S, Li XJ. Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity. Cell Reports. 25: 2653-2659.e3. PMID 30517854 DOI: 10.1016/J.Celrep.2018.11.019 |
0.386 |
|
| 2018 |
Tu Z, Zhao H, Li B, Yan S, Wang L, Tang Y, Li Z, Bai D, Li C, Lin Y, Li Y, Liu J, Xu H, Guo X, Jiang YH, ... ... Li XJ, et al. CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms. Human Molecular Genetics. PMID 30329048 DOI: 10.1093/Hmg/Ddy367 |
0.341 |
|
| 2018 |
Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, Yang W, Zhao Y, Ouyang Z, Lai C, Yang H, Li L, Liu Q, Shi H, Xu G, ... ... Li XJ, et al. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. Cell. PMID 29606351 DOI: 10.1016/J.Cell.2018.03.005 |
0.473 |
|
| 2018 |
Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, Tang B, Jin P, Li XJ, Yang S, Li S. Piperine ameliorates SCA17 neuropathology by reducing ER stress. Molecular Neurodegeneration. 13: 4. PMID 29378605 DOI: 10.1186/S13024-018-0236-X |
0.46 |
|
| 2017 |
Yang S, Yang H, Chang R, Yin P, Yang Y, Yang W, Huang S, Gaertig MA, Li S, Li XJ. MANF regulates hypothalamic control of food intake and body weight. Nature Communications. 8: 579. PMID 28924165 DOI: 10.1038/S41467-017-00750-X |
0.316 |
|
| 2017 |
Hong Y, Zhao T, Li XJ, Li S. Mutant huntingtin inhibits αB-crystallin expression and impairs exosome secretion from astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28893927 DOI: 10.1523/Jneurosci.1418-17.2017 |
0.506 |
|
| 2017 |
Zhao T, Hong Y, Yin P, Li S, Li XJ. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847953 DOI: 10.1073/Pnas.1710549114 |
0.507 |
|
| 2017 |
Yang Y, Yang S, Guo J, Cui Y, Tang B, Li XJ, Li S. Synergistic toxicity of polyglutamine-expanded TBP in glia and neuronal cells: therapeutic implications for SCA17. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821675 DOI: 10.1523/Jneurosci.0111-17.2017 |
0.512 |
|
| 2017 |
Zhao H, Tu Z, Xu H, Yan S, Yan H, Zheng Y, Yang W, Zheng J, Li Z, Tian R, Lu Y, Guo X, Jiang YH, Li XJ, Zhang YQ. Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate. Cell Research. PMID 28741620 DOI: 10.1038/Cr.2017.95 |
0.312 |
|
| 2017 |
Yang S, Chang R, Yang H, Zhao T, Hong Y, Kong HE, Sun X, Qin Z, Jin P, Li S, Li XJ. CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease. The Journal of Clinical Investigation. PMID 28628038 DOI: 10.1172/Jci92087 |
0.492 |
|
| 2017 |
Yan S, Tu Z, Li S, Li XJ. Use of CRISPR/Cas9 to model brain diseases. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28392484 DOI: 10.1016/J.Pnpbp.2017.04.003 |
0.374 |
|
| 2017 |
Xiang J, Yang S, Xin N, Gaertig MA, Reeves RH, Li S, Li XJ. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137862 DOI: 10.1073/Pnas.1614893114 |
0.341 |
|
| 2017 |
Lim Y, Wu LL, Chen S, Sun Y, Vijayaraj SL, Yang M, Bobrovskaya L, Keating D, Li XJ, Zhou XF. HAP1 Is Required for Endocytosis and Signalling of BDNF and Its Receptors in Neurons. Molecular Neurobiology. PMID 28083816 DOI: 10.1007/S12035-016-0379-0 |
0.385 |
|
| 2016 |
Cui Y, Yang S, Li XJ, Li S. Genetically modified rodent models of SCA17. Journal of Neuroscience Research. PMID 27859490 DOI: 10.1002/Jnr.23984 |
0.41 |
|
| 2016 |
Hong Y, Zhao T, Li XJ, Li S. Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8790-801. PMID 27559163 DOI: 10.1523/Jneurosci.0168-16.2016 |
0.422 |
|
| 2016 |
Zhao T, Hong Y, Li S, Li XJ. Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8317-28. PMID 27511006 DOI: 10.1523/Jneurosci.0806-16.2016 |
0.531 |
|
| 2016 |
Liu X, Wang CE, Hong Y, Zhao T, Wang G, Gaertig MA, Sun M, Li S, Li XJ. N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy. Plos Genetics. 12: e1006083. PMID 27203582 DOI: 10.1371/Journal.Pgen.1006083 |
0.513 |
|
| 2016 |
Yang W, Tu Z, Sun Q, Li XJ. CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases. Frontiers in Molecular Neuroscience. 9: 30. PMID 27199655 DOI: 10.3389/Fnmol.2016.00030 |
0.339 |
|
| 2016 |
Zhao T, Hong Y, Li XJ, Li SH. Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review. Frontiers in Molecular Neuroscience. 9: 27. PMID 27147961 DOI: 10.3389/Fnmol.2016.00027 |
0.528 |
|
| 2016 |
Wang G, Liu X, Gaertig MA, Li S, Li XJ. Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951659 DOI: 10.1073/Pnas.1524575113 |
0.449 |
|
| 2015 |
Huang S, Yang S, Guo J, Yan S, Gaertig MA, Li S, Li XJ. Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice. Cell Reports. PMID 26387956 DOI: 10.1016/J.Celrep.2015.08.060 |
0.388 |
|
| 2015 |
Wang G, Yang H, Yan S, Wang CE, Liu X, Zhao B, Ouyang Z, Yin P, Liu Z, Zhao Y, Liu T, Fan N, Guo L, Li S, Li XJ, et al. Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain. Molecular Neurodegeneration. 10: 42. PMID 26334913 DOI: 10.1186/S13024-015-0036-5 |
0.461 |
|
| 2015 |
Tu Z, Yang W, Yan S, Guo X, Li XJ. CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases. Molecular Neurodegeneration. 10: 35. PMID 26238861 DOI: 10.1186/S13024-015-0031-X |
0.315 |
|
| 2015 |
Jiang W, Wei W, Gaertig MA, Li S, Li XJ. Therapeutic Effect of Berberine on Huntington's Disease Transgenic Mouse Model. Plos One. 10: e0134142. PMID 26225560 DOI: 10.1371/Journal.Pone.0134142 |
0.505 |
|
| 2015 |
Yang W, Wang G, Wang CE, Guo X, Yin P, Gao J, Tu Z, Wang Z, Wu J, Hu X, Li S, Li XJ. Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8345-58. PMID 26019347 DOI: 10.1523/Jneurosci.0772-15.2015 |
0.364 |
|
| 2015 |
Chan AW, Jiang J, Chen Y, Li C, Prucha MS, Hu Y, Chi T, Moran S, Rahim T, Li S, Li X, Zola SM, Testa CM, Mao H, Villalba R, et al. Progressive cognitive deficit, motor impairment and striatal pathology in a transgenic Huntington disease monkey model from infancy to adulthood. Plos One. 10: e0122335. PMID 25966278 DOI: 10.1371/Journal.Pone.0122335 |
0.396 |
|
| 2015 |
Chang R, Liu X, Li S, Li XJ. Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy. Drug Design, Development and Therapy. 9: 2179-88. PMID 25931812 DOI: 10.2147/Dddt.S58470 |
0.485 |
|
| 2015 |
Xiang J, Yan S, Li SH, Li XJ. Postnatal loss of hap1 reduces hippocampal neurogenesis and causes adult depressive-like behavior in mice. Plos Genetics. 11: e1005175. PMID 25875952 DOI: 10.1371/Journal.Pgen.1005175 |
0.351 |
|
| 2015 |
Huang B, Wei W, Wang G, Gaertig MA, Feng Y, Wang W, Li XJ, Li S. Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes. Neuron. 85: 1212-26. PMID 25789755 DOI: 10.1016/J.Neuron.2015.02.026 |
0.437 |
|
| 2015 |
Jiang W, Li SH, Li X. Therapeutic potential of berberine against neurodegenerative diseases Science China-Life Sciences. 58: 564-569. PMID 25749423 DOI: 10.1007/S11427-015-4829-0 |
0.339 |
|
| 2015 |
Yin P, Tu Z, Yin A, Zhao T, Yan S, Guo X, Chang R, Zhang L, Hong Y, Huang X, Zhou J, Wang Y, Li S, Li XJ. Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin. Human Molecular Genetics. 24: 1350-62. PMID 25343992 DOI: 10.1093/Hmg/Ddu544 |
0.452 |
|
| 2015 |
Li XJ, Li S. Large Animal Models of Huntington's Disease. Current Topics in Behavioral Neurosciences. 22: 149-60. PMID 24048953 DOI: 10.1007/7854_2013_246 |
0.489 |
|
| 2014 |
Wade BE, Wang CE, Yan S, Bhat K, Huang B, Li S, Li XJ. Ubiquitin-activating enzyme activity contributes to differential accumulation of mutant huntingtin in brain and peripheral tissues. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8411-22. PMID 24948797 DOI: 10.1523/Jneurosci.0775-14.2014 |
0.818 |
|
| 2014 |
Bhat KP, Yan S, Wang CE, Li S, Li XJ. Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A. Proceedings of the National Academy of Sciences of the United States of America. 111: 5706-11. PMID 24706802 DOI: 10.1073/Pnas.1402215111 |
0.437 |
|
| 2014 |
Yang S, Huang S, Gaertig MA, Li XJ, Li S. Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice. Neuron. 81: 349-65. PMID 24462098 DOI: 10.1016/J.Neuron.2013.12.002 |
0.493 |
|
| 2014 |
Yan S, Wang CE, Wei W, Gaertig MA, Lai L, Li S, Li XJ. TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain. Human Molecular Genetics. 23: 2678-93. PMID 24381309 DOI: 10.1093/Hmg/Ddt662 |
0.516 |
|
| 2014 |
Xiang J, Yang H, Zhao T, Sun M, Xu X, Zhou XF, Li SH, Li XJ. Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting. The Journal of Clinical Investigation. 124: 85-98. PMID 24355921 DOI: 10.1172/Jci69206 |
0.47 |
|
| 2013 |
Xu Q, Huang S, Song M, Wang CE, Yan S, Liu X, Gaertig MA, Yu SP, Li H, Li S, Li XJ. Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms. The Journal of Cell Biology. 202: 1123-38. PMID 24081492 DOI: 10.1083/Jcb.201303146 |
0.454 |
|
| 2013 |
Weng L, Lin YF, Li AL, Wang CE, Yan S, Sun M, Gaertig MA, Mitha N, Kosaka J, Wakabayashi T, Xu X, Tang B, Li S, Li XJ. Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8172-84. PMID 23658157 DOI: 10.1523/Jneurosci.0119-13.2013 |
0.398 |
|
| 2012 |
Li XJ, Li S. Influence of species differences on the neuropathology of transgenic Huntington's disease animal models. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 239-45. PMID 22749010 DOI: 10.1016/J.Jgg.2012.05.002 |
0.46 |
|
| 2012 |
Li XJ, Li W. Beyond mice: genetically modifying larger animals to model human diseases. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 237-8. PMID 22749009 DOI: 10.1016/J.Jgg.2012.05.006 |
0.337 |
|
| 2012 |
Li S, Li XJ. A huntingtin-HAP1-PCM1 pathway in ciliogenesis. Expert Review of Proteomics. 9: 17-9. PMID 22292820 DOI: 10.1586/Epr.11.72 |
0.469 |
|
| 2012 |
Cape A, Chen X, Wang CE, O'Neill A, Lin YF, He J, Xu XS, Yi H, Li H, Li S, Li XJ. Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells. Cellular and Molecular Life Sciences : Cmls. 69: 1305-17. PMID 21544547 DOI: 10.1007/S00018-011-0692-8 |
0.774 |
|
| 2012 |
Li X, Li S. Neuropathology of transgenic HD animal models Molecular Neurodegeneration. 7: 1-1. DOI: 10.1186/1750-1326-7-S1-L17 |
0.416 |
|
| 2011 |
Mandal M, Wei J, Zhong P, Cheng J, Duffney LJ, Liu W, Yuen EY, Twelvetrees AE, Li S, Li XJ, Kittler JT, Yan Z. Impaired alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and function by mutant huntingtin. The Journal of Biological Chemistry. 286: 33719-28. PMID 21832090 DOI: 10.1074/Jbc.M111.236521 |
0.448 |
|
| 2011 |
Huang S, Ling JJ, Yang S, Li XJ, Li S. Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor. Brain : a Journal of Neurology. 134: 1943-58. PMID 21705419 DOI: 10.1093/Brain/Awr146 |
0.549 |
|
| 2011 |
Yang M, Lim Y, Li X, Zhong J, Zhou X. Precursor of Brain-derived Neurotrophic Factor (proBDNF) Forms a Complex with Huntingtin-associated Protein-1 (HAP1) and Sortilin That Modulates proBDNF Trafficking, Degradation, and Processing Journal of Biological Chemistry. 286: 16272-16284. PMID 21357693 DOI: 10.1074/Jbc.M110.195347 |
0.452 |
|
| 2011 |
Havel LS, Wang CE, Wade B, Huang B, Li S, Li XJ. Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation. Human Molecular Genetics. 20: 1424-37. PMID 21245084 DOI: 10.1093/Hmg/Ddr023 |
0.819 |
|
| 2011 |
Li XJ, Li S. Proteasomal dysfunction in aging and Huntington disease. Neurobiology of Disease. 43: 4-8. PMID 21145396 DOI: 10.1016/J.Nbd.2010.11.018 |
0.491 |
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| 2010 |
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Li SH, Gutekunst CA, Hersch SM, Li XJ. Association of HAP1 isoforms with a unique cytoplasmic structure. Journal of Neurochemistry. 71: 2178-85. PMID 9798945 DOI: 10.1046/J.1471-4159.1998.71052178.X |
0.38 |
|
| 1998 |
Gutekunst CA, Li SH, Yi H, Ferrante RJ, Li XJ, Hersch SM. The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7674-86. PMID 9742138 DOI: 10.1523/Jneurosci.18-19-07674.1998 |
0.427 |
|
| 1998 |
Li SH, Hosseini SH, Gutekunst CA, Hersch SM, Ferrante RJ, Li XJ. A human HAP1 homologue. Cloning, expression, and interaction with huntingtin. The Journal of Biological Chemistry. 273: 19220-7. PMID 9668110 DOI: 10.1074/Jbc.273.30.19220 |
0.42 |
|
| 1998 |
Li S, Li X. Aggregation of N-Terminal Huntingtin is Dependent on the Length of Its Glutamine Repeats Human Molecular Genetics. 7: 777-782. PMID 9536080 DOI: 10.1093/Hmg/7.5.777 |
0.467 |
|
| 1998 |
Li SH, Gutekunst CA, Hersch SM, Li XJ. Interaction of huntingtin-associated protein with dynactin P150Glued. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1261-9. PMID 9454836 DOI: 10.1523/Jneurosci.18-04-01261.1998 |
0.419 |
|
| 1998 |
Reddy TR, Li X, Jones Y, Ellisman MH, Ching GY, Liem RK, Wong-Staal F. Specific interaction of HTLV tax protein and a human type IV neuronal intermediate filament protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 702-7. PMID 9435256 DOI: 10.1073/Pnas.95.2.702 |
0.308 |
|
| 1995 |
Sharp AH, Loev SJ, Schilling G, Li SH, Li XJ, Bao J, Wagster MV, Kotzuk JA, Steiner JP, Lo A. Widespread expression of Huntington's disease gene (IT15) protein product. Neuron. 14: 1065-74. PMID 7748554 DOI: 10.1016/0896-6273(95)90345-3 |
0.379 |
|
| 1995 |
Li XJ, Snyder SH. Molecular cloning of Ebnerin, a von Ebner's gland protein associated with taste buds. The Journal of Biological Chemistry. 270: 17674-9. PMID 7629065 DOI: 10.1074/Jbc.270.30.17674 |
0.346 |
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| 1995 |
Li XJ, Li SH, Sharp AH, Nucifora FC, Schilling G, Lanahan A, Worley P, Snyder SH, Ross CA. A huntingtin-associated protein enriched in brain with implications for pathology. Nature. 378: 398-402. PMID 7477378 DOI: 10.1038/378398A0 |
0.367 |
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