Year |
Citation |
Score |
2001 |
Groutas WC, He S, Kuang R, Ruan S, Tu J, Chan HK. Inhibition of serine proteases by functionalized sulfonamides coupled to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold. Bioorganic & Medicinal Chemistry. 9: 1543-8. PMID 11408173 DOI: 10.1016/S0968-0896(01)00037-2 |
0.605 |
|
2001 |
Groutas WC, Epp JB, Kuang R, Ruan S, Chong LS, Venkataraman R, Tu J, He S, Yu H, Fu Q, Li YH, Truong TM, Vu NT. 1,2,5-Thiadiazolidin-3-one 1,1 dioxide: a powerful scaffold for probing the S' subsites of (chymo)trypsin-like serine proteases. Archives of Biochemistry and Biophysics. 385: 162-9. PMID 11361013 DOI: 10.1006/Abbi.2000.2139 |
0.637 |
|
2001 |
He S, Yu H, Fu Q, Kuang R, Epp JB, Groutas WC. A one-step protocol for the N-chloromethylation of heterocyclic imides Synthetic Communications. 31: 3055-3058. DOI: 10.1081/Scc-100105876 |
0.472 |
|
2000 |
He S, Kuang R, Venkataraman R, Tu J, Truong TM, Chan HK, Groutas WC. Potent inhibition of serine proteases by heterocyclic sulfide derivatives of 1,2,5-thiadiazolidin-3-one 1,1 dioxide. Bioorganic & Medicinal Chemistry. 8: 1713-7. PMID 10976518 DOI: 10.1016/S0968-0896(00)00101-2 |
0.646 |
|
2000 |
Kuang R, Epp JB, Ruan S, Chong LS, Venkataraman R, Tu J, He S, Truong TM, Groutas WC. Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylates. Bioorganic & Medicinal Chemistry. 8: 1005-16. PMID 10882012 DOI: 10.1016/S0968-0896(00)00038-9 |
0.639 |
|
1999 |
Groutas WC, Schechter NM, He S, Yu H, Huang P, Tu J. Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold. Bioorganic & Medicinal Chemistry Letters. 9: 2199-204. PMID 10465545 DOI: 10.1016/S0960-894X(99)00377-7 |
0.605 |
|
1999 |
Kuang R, Epp JB, Ruan S, Yu H, Huang P, He S, Tu J, Schechter NM, Turbov J, Froelich CJ, Groutas WC. A General Inhibitor Scaffold for Serine Proteases with a (Chymo)trypsin-Like Fold: Solution-Phase Construction and Evaluation of the First Series of Libraries of Mechanism-Based Inhibitors Journal of the American Chemical Society. 121: 8128-8129. DOI: 10.1021/Ja990160E |
0.577 |
|
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