| Year |
Citation |
Score |
| 2006 |
Bruck J, Ebenhöh O, Heinrich R. Patterns of interactions of reaction pairs in metabolic networks. Genome Informatics. International Conference On Genome Informatics. 17: 208-18. PMID 17503370 DOI: 10.11234/Gi1990.17.208 |
0.32 |
|
| 2005 |
Handorf T, Ebenhöh O, Heinrich R. Expanding metabolic networks: scopes of compounds, robustness, and evolution. Journal of Molecular Evolution. 61: 498-512. PMID 16155745 DOI: 10.1007/S00239-005-0027-1 |
0.347 |
|
| 2005 |
Hornberg JJ, Binder B, Bruggeman FJ, Schoeberl B, Heinrich R, Westerhoff HV. Control of MAPK signalling: from complexity to what really matters. Oncogene. 24: 5533-42. PMID 16007170 DOI: 10.1038/Sj.Onc.1208817 |
0.336 |
|
| 2005 |
Heinrich R, Rapoport TA. Generation of nonidentical compartments in vesicular transport systems. The Journal of Cell Biology. 168: 271-80. PMID 15657397 DOI: 10.1083/Jcb.200409087 |
0.501 |
|
| 2004 |
Krüger R, Heinrich R. Model reduction and analysis of robustness for the Wnt/beta-catenin signal transduction pathway. Genome Informatics. International Conference On Genome Informatics. 15: 138-48. PMID 15712117 DOI: 10.11234/Gi1990.15.138 |
0.362 |
|
| 2004 |
Ebenhöh O, Handorf T, Heinrich R. Structural analysis of expanding metabolic networks. Genome Informatics. International Conference On Genome Informatics. 15: 35-45. PMID 15712108 DOI: 10.11234/Gi1990.15.35 |
0.302 |
|
| 2004 |
Liebermeister W, Klipp E, Schuster S, Heinrich R. A theory of optimal differential gene expression. Bio Systems. 76: 261-78. PMID 15351149 DOI: 10.1016/J.Biosystems.2004.05.022 |
0.308 |
|
| 2003 |
Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. Plos Biology. 1: E10. PMID 14551908 DOI: 10.1371/Journal.Pbio.0000010 |
0.327 |
|
| 2002 |
Klipp E, Heinrich R, Holzhütter HG. Prediction of temporal gene expression. Metabolic opimization by re-distribution of enzyme activities. European Journal of Biochemistry / Febs. 269: 5406-13. PMID 12423338 DOI: 10.1046/J.1432-1033.2002.03223.X |
0.355 |
|
| 2002 |
Castiglione F, Bernaschi M, Succi S, Heinrich R, Kirschner MW. Intracellular signal propagation in a two-dimensional autocatalytic reaction model. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 66: 031905. PMID 12366150 DOI: 10.1103/Physreve.66.031905 |
0.3 |
|
| 2002 |
Binder B, Heinrich R. Dynamic stability of signal transduction networks depending on downstream and upstream specificity of protein kinases. Molecular Biology Reports. 29: 51-5. PMID 12241074 DOI: 10.1023/A:1020302318189 |
0.307 |
|
| 2002 |
Heinrich R, Neel BG, Rapoport TA. Mathematical models of protein kinase signal transduction. Molecular Cell. 9: 957-70. PMID 12049733 DOI: 10.1016/S1097-2765(02)00528-2 |
0.52 |
|
| 2002 |
Heinrich R, Meléndez-Hevia E, Cabezas H. Optimization of kinetic parameters of enzymes Biochemistry and Molecular Biology Education. 30: 184-188. DOI: 10.1002/Bmb.2002.494030030065 |
0.319 |
|
| 2001 |
Wolf J, Sohn H, Heinrich R, Kuriyama H. Mathematical analysis of a mechanism for autonomous metabolic oscillations in continuous culture of Saccharomyces cerevisiae. Febs Letters. 499: 230-4. PMID 11423122 DOI: 10.1016/S0014-5793(01)02562-5 |
0.344 |
|
| 2001 |
Liebermeister W, Rapoport TA, Heinrich R. Ratcheting in post-translational protein translocation: a mathematical model. Journal of Molecular Biology. 305: 643-56. PMID 11152619 DOI: 10.1006/Jmbi.2000.4302 |
0.543 |
|
| 2001 |
Ebenhöh O, Heinrich R. Evolutionary optimization of metabolic pathways. Theoretical reconstruction of the stoichiometry of ATP and NADH producing systems. Bulletin of Mathematical Biology. 63: 21-55. PMID 11146883 DOI: 10.1006/Bulm.2000.0197 |
0.395 |
|
| 2000 |
Wolf J, Heinrich R. Effect of cellular interaction on glycolytic oscillations in yeast: a theoretical investigation. The Biochemical Journal. 345: 321-34. PMID 10702114 DOI: 10.1042/Bj3450321 |
0.338 |
|
| 2000 |
Wolf J, Passarge J, Somsen OJ, Snoep JL, Heinrich R, Westerhoff HV. Transduction of intracellular and intercellular dynamics in yeast glycolytic oscillations. Biophysical Journal. 78: 1145-53. PMID 10692304 DOI: 10.1016/S0006-3495(00)76672-0 |
0.315 |
|
| 1999 |
Klipp E, Heinrich R. Competition for enzymes in metabolic pathways: implications for optimal distributions of enzyme concentrations and for the distribution of flux control. Bio Systems. 54: 1-14. PMID 10658833 DOI: 10.1016/S0303-2647(99)00059-3 |
0.375 |
|
| 1999 |
Stephani A, Nuño JC, Heinrich R. Optimal stoichiometric designs of ATP-producing systems as determined by an evolutionary algorithm. Journal of Theoretical Biology. 199: 45-61. PMID 10419759 DOI: 10.1006/Jtbi.1999.0942 |
0.354 |
|
| 1999 |
Schilling CH, Schuster S, Palsson BO, Heinrich R. Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era. Biotechnology Progress. 15: 296-303. PMID 10356246 DOI: 10.1021/Bp990048K |
0.346 |
|
| 1999 |
Frickenhaus S, Heinrich R. Kinetic models and phenomenological analysis of passive lipid translocation in single-file. Journal of Theoretical Biology. 197: 175-91. PMID 10074392 DOI: 10.1006/Jtbi.1998.0871 |
0.346 |
|
| 1999 |
Frickenhaus S, Heinrich R. Kinetic and thermodynamic aspects of lipid translocation in biological membranes. Biophysical Journal. 76: 1293-309. PMID 10049313 DOI: 10.1016/S0006-3495(99)77292-9 |
0.328 |
|
| 1998 |
Frickenhaus S, Herrmann A, Heinrich R. Compensating lipid fluxes generated by the aminophospholipid translocase. Molecular Membrane Biology. 15: 213-20. PMID 10087508 DOI: 10.3109/09687689709044323 |
0.317 |
|
| 1998 |
Heinrich R, Schuster S. The modelling of metabolic systems. Structure, control and optimality Biosystems. 47: 61-77. PMID 9715751 DOI: 10.1016/S0303-2647(98)00013-6 |
0.398 |
|
| 1998 |
Stephani A, Heinrich R. Kinetic and thermodynamic principles determining the structural design of ATP-producing systems Bulletin of Mathematical Biology. 60: 505-543. PMID 9652953 DOI: 10.1006/Bulm.1997.0028 |
0.408 |
|
| 1998 |
Heinrich R. Optimization and Control of Metabolic Systems Ifac Proceedings Volumes. 31: 331-336. DOI: 10.1016/S1474-6670(17)40207-2 |
0.39 |
|
| 1997 |
Wolf J, Heinrich R. Dynamics of two-component biochemical systems in interacting cells; Synchronization and desynchronization of oscillations and multiple steady states Biosystems. 43: 1-24. PMID 9224551 DOI: 10.1016/S0303-2647(97)01688-2 |
0.368 |
|
| 1997 |
Heinrich R, Brumen M, Jaeger A, Müller P, Herrmann A. Modelling of phospholipid translocation in the erythrocyte membrane: a combined kinetic and thermodynamic approach. Journal of Theoretical Biology. 185: 295-312. PMID 9156082 DOI: 10.1006/Jtbi.1996.0325 |
0.346 |
|
| 1997 |
Meléndez-Hevia E, Waddell TG, Heinrich R, Montero F. Theoretical approaches to the evolutionary optimization of glycolysis. Chemical analysis European Journal of Biochemistry. 244: 527-543. PMID 9119021 DOI: 10.1111/J.1432-1033.1997.T01-1-00527.X |
0.336 |
|
| 1997 |
Wolf J, Heinrich R. Dynamics of biochemical oscillators in a large number of interacting cells Nonlinear Analysis, Theory, Methods and Applications. 30: 1835-1845. DOI: 10.1016/S0362-546X(96)00346-X |
0.332 |
|
| 1997 |
Waddell TG, Repovic P, Melendez-Hevia E, Heinrich R, Montero F. Optimization of glycolysis: A new look at the efficiency of energy coupling Biochemical Education. 25: 204-205. DOI: 10.1016/S0307-4412(97)00131-3 |
0.325 |
|
| 1997 |
Marhl M, Schuster S, Brumen M, Heinrich R. Modelling the interrelations between calcium oscillations and ER membrane potential oscillations Biophysical Chemistry. 63: 221-239. DOI: 10.1016/S0301-4622(96)02248-X |
0.306 |
|
| 1996 |
Heinrich R, Klipp E. Control analysis of unbranched enzymatic chains in states of maximal activity Journal of Theoretical Biology. 182: 243-252. PMID 8944155 DOI: 10.1006/Jtbi.1996.0161 |
0.412 |
|
| 1996 |
Wilhelm T, Heinrich R. Mathematical analysis of the smallest chemical reaction system with Hopf bifurcation Journal of Mathematical Chemistry. 19: 111-130. DOI: 10.1007/Bf01165179 |
0.331 |
|
| 1995 |
WILHELM T, HEINRICH R. A CHEMICAL SYSTEM WITH HOPF BIFURCATION CONSISTING OF THREE INTERMEDIATES AND MONO- AND BIMOLECULAR REACTIONS Journal of Biological Systems. 3: 231-238. DOI: 10.1142/S0218339095000228 |
0.301 |
|
| 1995 |
Heinrich R. Principles Of Metabolic Control Theory Journal of Biological Systems. 3: 115-125. DOI: 10.1142/S0218339095000113 |
0.341 |
|
| 1995 |
BRUMEN M, HEINRICH R, HERRMANN A, MÜLLER P. A KINETIC MODEL OF PHOSPHOLIPID TRANSLOCATION IN THE ERYTHROCYTE MEMBRANE Journal of Biological Systems. 3: 95-103. DOI: 10.1142/S0218339095000095 |
0.345 |
|
| 1995 |
Kholodenko BN, Molenaar D, Schuster S, Heinrich R, Westerhoff HV. Defining control coefficients in non-ideal metabolic pathways Biophysical Chemistry. 56: 215-226. DOI: 10.1016/0301-4622(95)00039-Z |
0.366 |
|
| 1994 |
Klipp E, Heinrich R. Evolutionary optimization of enzyme kinetic parameters; effect of constraints Journal of Theoretical Biology. 171: 309-323. PMID 7869733 DOI: 10.1006/Jtbi.1994.1234 |
0.377 |
|
| 1994 |
Wilhelm T, Hoffmann-Klipp E, Heinrich R. An evolutionary approach to enzyme kinetics: Optimization of ordered mechanisms Bulletin of Mathematical Biology. 56: 65-106. DOI: 10.1016/S0092-8240(05)80206-X |
0.373 |
|
| 1993 |
Brumen M, Heinrich R, Herrmann A, Müller P. Mathematical modelling of lipid transbilayer movement in the human erythrocyte plasma membrane European Biophysics Journal. 22: 213-223. PMID 8404726 DOI: 10.1007/Bf00185783 |
0.324 |
|
| 1993 |
Hofer T, Heinrich R. A second-order approach to metabolic control analysis Journal of Theoretical Biology. 164: 85-102. PMID 8264245 DOI: 10.1006/Jtbi.1993.1141 |
0.372 |
|
| 1992 |
Schuster S, Heinrich R. The definitions of metabolic control analysis revisited Biosystems. 27: 1-15. PMID 1391687 DOI: 10.1016/0303-2647(92)90042-W |
0.337 |
|
| 1991 |
Heinrich R, Hoffmann E. Kinetic parameters of enzymatic reactions in states of maximal activity; An evolutionary approach Journal of Theoretical Biology. 151: 249-283. PMID 1943142 DOI: 10.1016/S0022-5193(05)80363-7 |
0.378 |
|
| 1991 |
Heinrich R, Schuster S, Holzhütter H. Mathematical analysis of enzymic reaction systems using optimization principles. Febs Journal. 201: 1-21. PMID 1915354 DOI: 10.1111/J.1432-1033.1991.Tb16251.X |
0.416 |
|
| 1991 |
Heinrich R, Reder C. Metabolic control analysis of relaxation processes Journal of Theoretical Biology. 151: 343-350. DOI: 10.1016/S0022-5193(05)80383-2 |
0.392 |
|
| 1988 |
Heinrich R, Holzhütter HG, Schuster S. A theoretical approach to the evolution and structural design of enzymatic networks: linear enzymatic chains, branched pathways and glycolysis of erythrocytes. Bulletin of Mathematical Biology. 49: 539-95. PMID 3435799 DOI: 10.1016/S0092-8240(87)90003-6 |
0.424 |
|
| 1987 |
Schuster S, Heinrich R. Time hierarchy in enzymatic reaction chains resulting from optimality principles Journal of Theoretical Biology. 129: 189-209. PMID 3455462 DOI: 10.1016/S0022-5193(87)80012-7 |
0.344 |
|
| 1987 |
Rapoport TA, Heinrich R, Walter P, Schulmeister T. Mathematical modeling of the effects of the signal recognition particle on translation and translocation of proteins across the endoplasmic reticulum membrane. Journal of Molecular Biology. 195: 621-36. PMID 2821280 DOI: 10.1016/0022-2836(87)90186-0 |
0.544 |
|
| 1985 |
Heinrich R. Mathematical models of metabolic systems: general principles and control of glycolysis and membrane transport in erythrocytes Biomedica Biochimica Acta. 44: 913-927. PMID 2931078 |
0.317 |
|
| 1985 |
Burns JA, Cornish-Bowden A, Groen AK, Heinrich R, Kacser H, Porteous JW, Rapoport SM, Rapoport TA, Stucki JW, Tager JM, Wanders RJA, Westerhoff HV. Control analysis of metabolic systems Trends in Biochemical Sciences. 10: 16. DOI: 10.1016/0968-0004(85)90008-8 |
0.526 |
|
| 1984 |
Brumen M, Heinrich R. A metabolic osmotic model of human erythrocytes Biosystems. 17: 155-169. PMID 6525455 DOI: 10.1016/0303-2647(84)90006-6 |
0.413 |
|
| 1984 |
Heinrich R, Gaestel M, Müller T. A theoretical approach to cluster formation in biological membranes Biosystems. 17: 135-154. PMID 6525454 DOI: 10.1016/0303-2647(84)90005-4 |
0.3 |
|
| 1983 |
Heinrich R, Rapoport SM. The utility of mathematical models for the understanding of metabolic systems Biochemical Society Transactions. 11: 31-35. PMID 6825912 DOI: 10.1042/Bst0110031 |
0.346 |
|
| 1982 |
Heinrich R, Sonntag I. Dynamics of non-linear biochemical systems and the evolutionary significance of time hierarchy Biosystems. 15: 301-316. PMID 7165797 DOI: 10.1016/0303-2647(82)90045-4 |
0.37 |
|
| 1980 |
Heinrich R, Rapoport TA. Mathematical modelling of translation of mRNA in eucaryotes; steady state, time-dependent processes and application to reticulocytes. Journal of Theoretical Biology. 86: 279-313. PMID 7442295 DOI: 10.1016/0022-5193(80)90008-9 |
0.517 |
|
| 1980 |
Schauer M, Heinrich R. Analysis of the quasi-steady-state approximation for an enzymatic one-substrate reaction. Journal of Theoretical Biology. 79: 425-42. PMID 513815 DOI: 10.1016/0022-5193(79)90235-2 |
0.357 |
|
| 1977 |
Heinrich R, Rapoport SM, Rapoport TA. Metabolic regulation and mathematical models. Progress in Biophysics and Molecular Biology. 32: 1-82. PMID 343173 DOI: 10.1016/0079-6107(78)90017-2 |
0.57 |
|
| 1977 |
Rapoport TA, Otto M, Heinrich R. An extended model of the glycolysis in erythrocytes. Acta Biologica Et Medica Germanica. 36: 461-8. PMID 145774 |
0.508 |
|
| 1977 |
Otto M, Heinrich R, Jacobasch G, Rapoport S. A mathematical model for the influence of anionic effectors on the phosphofructokinase from rat erythrocytes. European Journal of Biochemistry. 74: 413-20. PMID 140047 DOI: 10.1111/J.1432-1033.1977.Tb11406.X |
0.355 |
|
| 1977 |
Schulz J, Baufeld A, Hofmann E, Rapoport TA, Heinrich R, Rapoport SM. Regulation of anaerobic glycolysis in Ehrlich ascites tumour cells. Acta Biologica Et Medica Germanica. 36: 1379-91. PMID 28629 |
0.47 |
|
| 1976 |
Rapoport TA, Heinrich R, Rapoport SM. The regulatory principles of glycolysis in erythrocytes in vivo and in vitro. A minimal comprehensive model describing steady states, quasi-steady states and time-dependent processes. The Biochemical Journal. 154: 449-69. PMID 132930 DOI: 10.1042/Bj1540449 |
0.598 |
|
| 1975 |
Rapoport TA, Heinrich R. Mathematical analysis of multienzyme systems. I. Modelling of the glycolysis of human erythrocytes. Bio Systems. 7: 120-9. PMID 168932 DOI: 10.1016/0303-2647(75)90049-0 |
0.566 |
|
| 1975 |
Heinrich R, Rapoport TA. Mathematical analysis of multienzyme systems. II. Steady state and transient control. Bio Systems. 7: 130-6. PMID 125616 DOI: 10.1016/0303-2647(75)90050-7 |
0.567 |
|
| 1974 |
Heinrich R, Rapoport TA. A linear steady-state treatment of enzymatic chains. Critique of the crossover theorem and a general procedure to identify interaction sites with an effector. European Journal of Biochemistry / Febs. 42: 97-105. PMID 4830199 DOI: 10.1111/J.1432-1033.1974.Tb03319.X |
0.575 |
|
| 1974 |
Heinrich R, Rapoport TA. A linear steady-state treatment of enzymatic chains. General properties, control and effector strength. European Journal of Biochemistry / Febs. 42: 89-95. PMID 4830198 DOI: 10.1111/J.1432-1033.1974.Tb03318.X |
0.576 |
|
| 1974 |
Gerber G, Preissler H, Heinrich R, Rapoport SM. Hexokinase of human erythrocytes. Purification, kinetic model and its application to the conditions in the cell. European Journal of Biochemistry / Febs. 45: 39-52. PMID 4421639 DOI: 10.1111/J.1432-1033.1974.Tb03527.X |
0.348 |
|
| 1974 |
Rapoport TA, Heinrich R, Jacobasch G, Rapoport S. A linear steady-state treatment of enzymatic chains. A mathematical model of glycolysis of human erythrocytes. European Journal of Biochemistry / Febs. 42: 107-20. PMID 4364392 DOI: 10.1111/J.1432-1033.1974.Tb03320.X |
0.532 |
|
| 1974 |
Otto M, Heinrich R, KUHN B, Jacobasch G. A mathematical model for the influence of fructose 6-phosphate, ATP, potassium, ammonium and magnesium on the phosphofructokinase from rat erythrocytes;. European Journal of Biochemistry / Febs. 49: 169-78. PMID 4282073 DOI: 10.1111/J.1432-1033.1974.Tb03822.X |
0.318 |
|
| 1973 |
Heinrich R, Rapoport TA. Linear theory of enzymatic chains; its application for the analysis of the crossover theorem and of the glycolysis of human erythrocytes. Acta Biologica Et Medica Germanica. 31: 479-94. PMID 4150081 |
0.439 |
|
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