Donald E. Ingber, MD, PhD - Publications

Affiliations: 
Wyss Institute Harvard Medical School, Boston, MA, United States 
Area:
biologically inspired engineering
Website:
http://wyss.harvard.edu/viewpage/121/donald-e-ingber

298 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Man Y, Zhai Y, Jiang A, Bai H, Gulati A, Plebani R, Mannix RJ, Merry GE, Goyal G, Belgur C, Hall SRR, Ingber DE. Exacerbation of influenza virus induced lung injury by alveolar macrophages and its suppression by pyroptosis blockade in a human lung alveolus chip. Biorxiv : the Preprint Server For Biology. PMID 39211234 DOI: 10.1101/2024.08.13.607799  0.724
2024 Izadifar Z, Cotton J, Chen S, Horvath V, Stejskalova A, Gulati A, LoGrande NT, Budnik B, Shahriar S, Doherty ER, Xie Y, To T, Gilpin SE, Sesay AM, Goyal G, ... ... Ingber DE, et al. Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips. Nature Communications. 15: 4578. PMID 38811586 DOI: 10.1038/s41467-024-48910-0  0.784
2023 Dasgupta Q, Jiang A, Wen AM, Mannix RJ, Man Y, Hall S, Javorsky E, Ingber DE. A human lung alveolus-on-a-chip model of acute radiation-induced lung injury. Nature Communications. 14: 6506. PMID 37845224 DOI: 10.1038/s41467-023-42171-z  0.696
2023 Strasser MK, Gibbs DL, Gascard P, Bons J, Hickey JW, Schürch CM, Tan Y, Black S, Chu P, Ozkan A, Basisty N, Sangwan V, Rose J, Shah S, Camilleri-Broet S, ... ... Ingber DE, et al. Concerted epithelial and stromal changes during progression of Barrett's Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysis. Biorxiv : the Preprint Server For Biology. PMID 37333362 DOI: 10.1101/2023.06.08.544265  0.803
2022 Izadifar Z, Sontheimer-Phelps A, Lubamba BA, Bai H, Fadel C, Stejskalova A, Ozkan A, Dasgupta Q, Bein A, Junaid A, Gulati A, Mahajan G, Kim S, LoGrande NT, Naziripour A, ... Ingber DE, et al. Modeling mucus physiology and pathophysiology in human organs-on-chips. Advanced Drug Delivery Reviews. 114542. PMID 36179916 DOI: 10.1016/j.addr.2022.114542  0.779
2022 Bai H, Si L, Jiang A, Belgur C, Zhai Y, Plebani R, Oh CY, Rodas M, Patil A, Nurani A, Gilpin SE, Powers RK, Goyal G, Prantil-Baun R, Ingber DE. Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip. Nature Communications. 13: 1928. PMID 35396513 DOI: 10.1038/s41467-022-29562-4  0.734
2022 Goyal G, Prabhala P, Mahajan G, Bausk B, Gilboa T, Xie L, Zhai Y, Lazarovits R, Mansour A, Kim MS, Patil A, Curran D, Long JM, Sharma S, Junaid A, ... ... Ingber DE, et al. Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ-on-a-Chip. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2103241. PMID 35289122 DOI: 10.1002/advs.202103241  0.739
2021 Robinson-McCarthy LR, Mijalis AJ, Filsinger GT, de Puig H, Donghia NM, Schaus TE, Rasmussen RA, Ferreira R, Lunshof JE, Chao G, Ter-Ovanesyan D, Dodd O, Kuru E, Sesay AM, Rainbow J, ... ... Ingber DE, et al. Laboratory-Generated DNA Can Cause Anomalous Pathogen Diagnostic Test Results. Microbiology Spectrum. e0031321. PMID 34523989 DOI: 10.1128/Spectrum.00313-21  0.328
2021 Grant J, Özkan A, Oh C, Mahajan G, Prantil-Baun R, Ingber DE. Simulating drug concentrations in PDMS microfluidic organ chips. Lab On a Chip. PMID 34346471 DOI: 10.1039/d1lc00348h  0.76
2021 Sahtoe DD, Coscia A, Mustafaoglu N, Miller LM, Olal D, Vulovic I, Yu TY, Goreshnik I, Lin YR, Clark L, Busch F, Stewart L, Wysocki VH, Ingber DE, Abraham J, et al. Transferrin receptor targeting by de novo sheet extension. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33879614 DOI: 10.1073/pnas.2021569118  0.76
2020 Herland A, Maoz BM, FitzGerald EA, Grevesse T, Vidoudez C, Sheehy SP, Budnik N, Dauth S, Mannix R, Budnik B, Parker KK, Ingber DE. Proteomic and Metabolomic Characterization of Human Neurovascular Unit Cells in Response to Methamphetamine. Advanced Biosystems. e1900230. PMID 32744807 DOI: 10.1002/adbi.201900230  0.535
2020 Tang H, Abouleila Y, Si L, Ortega-Prieto AM, Mummery CL, Ingber DE, Mashaghi A. Human Organs-on-Chips for Virology. Trends in Microbiology. PMID 32674988 DOI: 10.1016/J.Tim.2020.06.005  0.32
2020 Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, Wrighton PJ, Cox AG, Ingber DE, Goessling W, Daley GQ, North TE. YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Developmental Cell. PMID 32032546 DOI: 10.1016/J.Devcel.2020.01.006  0.352
2020 Herland A, Maoz BM, Das D, Somayaji MR, Prantil-Baun R, Novak R, Cronce M, Huffstater T, Jeanty SSF, Ingram M, Chalkiadaki A, Benson Chou D, Marquez S, Delahanty A, Jalili-Firoozinezhad S, ... ... Ingber DE, et al. Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips. Nature Biomedical Engineering. PMID 31988459 DOI: 10.1038/S41551-019-0498-9  0.514
2020 Novak R, Ingram M, Marquez S, Das D, Delahanty A, Herland A, Maoz BM, Jeanty SSF, Somayaji MR, Burt M, Calamari E, Chalkiadaki A, Cho A, Choe Y, Chou DB, ... ... Ingber DE, et al. Robotic fluidic coupling and interrogation of multiple vascularized organ chips. Nature Biomedical Engineering. PMID 31988458 DOI: 10.1038/S41551-019-0497-X  0.548
2020 Chou DB, Frismantas V, Milton Y, David R, Pop-Damkov P, Ferguson D, MacDonald A, Vargel Bölükbaşı Ö, Joyce CE, Moreira Teixeira LS, Rech A, Jiang A, Calamari E, Jalili-Firoozinezhad S, Furlong BA, ... ... Ingber DE, et al. On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology. Nature Biomedical Engineering. PMID 31988457 DOI: 10.1038/S41551-019-0495-Z  0.348
2019 Morad G, Carman CV, Hagedorn EJ, Perlin JR, Zon LI, Mustafaoglu N, Park TE, Ingber DE, Daisy CC, Moses MA. Tumor-Derived Extracellular Vesicles Breach the Intact Blood Brain Barrier via Transcytosis. Acs Nano. PMID 31479239 DOI: 10.1021/Acsnano.9B04397  0.773
2019 Zhang W, Qu L, Pei H, Qin Z, Didier J, Wu Z, Bobe F, Ingber DE, Weitz DA. Controllable Fabrication of Inhomogeneous Microcapsules for Triggered Release by Osmotic Pressure. Small (Weinheim An Der Bergstrasse, Germany). e1903087. PMID 31448553 DOI: 10.1002/Smll.201903087  0.755
2019 Mandriota N, Friedsam C, Jones-Molina JA, Tatem KV, Ingber DE, Sahin O. Cellular nanoscale stiffness patterns governed by intracellular forces. Nature Materials. PMID 31209386 DOI: 10.1038/S41563-019-0391-7  0.391
2019 Park TE, Mustafaoglu N, Herland A, Hasselkus R, Mannix R, FitzGerald EA, Prantil-Baun R, Watters A, Henry O, Benz M, Sanchez H, McCrea HJ, Goumnerova LC, Song HW, Palecek SP, ... ... Ingber DE, et al. Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies. Nature Communications. 10: 2621. PMID 31197168 DOI: 10.1038/S41467-019-10588-0  0.781
2019 Shin W, Hinojosa CD, Ingber DE, Kim HJ. Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip. Iscience. 15: 391-406. PMID 31108394 DOI: 10.1016/J.Isci.2019.04.037  0.753
2019 Sontheimer-Phelps A, Hassell BA, Ingber DE. Modelling cancer in microfluidic human organs-on-chips. Nature Reviews. Cancer. PMID 30647431 DOI: 10.1038/S41568-018-0104-6  0.383
2019 van der Helm MW, Henry OYF, Bein A, Hamkins-Indik T, Cronce MJ, Leineweber WD, Odijk M, van der Meer AD, Eijkel JCT, Ingber DE, van den Berg A, Segerink LI. Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy. Lab On a Chip. PMID 30632575 DOI: 10.1039/C8Lc00129D  0.332
2019 Ingber D. In search of cellular control: Signal transduction in context. Journal of Cellular Biochemistry. 232-237. PMID 29345815 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<232::Aid-Jcb28>3.0.Co;2-O  0.374
2018 Novak R, Didier M, Calamari E, Ng CF, Choe Y, Clauson SL, Nestor BA, Puerta J, Fleming R, Firoozinezhad SJ, Ingber DE. Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips. Journal of Visualized Experiments : Jove. PMID 30394380 DOI: 10.3791/58151  0.332
2018 Shi W, Didier J, Ingber D, Weitz DA. Collective shape actuation of polymer double emulsions by solvent evaporation. Acs Applied Materials & Interfaces. PMID 30199225 DOI: 10.1021/Acsami.8B13216  0.751
2018 Maoz BM, Herland A, FitzGerald EA, Grevesse T, Vidoudez C, Pacheco AR, Sheehy SP, Park TE, Dauth S, Mannix R, Budnik N, Shores K, Cho A, Nawroth JC, Segrè D, ... ... Ingber DE, et al. A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells. Nature Biotechnology. PMID 30125269 DOI: 10.1038/Nbt.4226  0.553
2018 Musah S, Dimitrakakis N, Camacho DM, Church GM, Ingber DE. Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip. Nature Protocols. 13: 1662-1685. PMID 29995874 DOI: 10.1038/S41596-018-0007-8  0.784
2018 Hassell BA, Goyal G, Lee E, Sontheimer-Phelps A, Levy O, Chen CS, Ingber DE. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Reports. 23: 3698. PMID 29925009 DOI: 10.1016/j.celrep.2018.06.028  0.777
2018 Ingber DE. Developmentally inspired human 'organs on chips'. Development (Cambridge, England). 145. PMID 29776965 DOI: 10.1242/Dev.156125  0.333
2018 Bastings M, Anastassacos F, Ponnuswamy N, Leifer F, Cuneo G, Lin C, Ingber DE, Ryu JH, Shih WM. Modulation of cellular uptake of DNA origami through control over mass and shape. Nano Letters. PMID 29756442 DOI: 10.1021/Acs.Nanolett.8B00660  0.327
2018 Bein A, Shin W, Jalili-Firoozinezhad S, Park MH, Sontheimer-Phelps A, Tovaglieri A, Chalkiadaki A, Kim HJ, Ingber DE. Microfluidic Organ-on-a-Chip Models of Human Intestine. Cellular and Molecular Gastroenterology and Hepatology. 5: 659-668. PMID 29713674 DOI: 10.1016/J.Jcmgh.2017.12.010  0.744
2018 Jalili-Firoozinezhad S, Prantil-Baun R, Jiang A, Potla R, Mammoto T, Weaver JC, Ferrante TC, Kim HJ, Cabral JMS, Levy O, Ingber DE. Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip. Cell Death & Disease. 9: 223. PMID 29445080 DOI: 10.1038/S41419-018-0304-8  0.433
2018 Kasendra M, Tovaglieri A, Sontheimer-Phelps A, Jalili-Firoozinezhad S, Bein A, Chalkiadaki A, Scholl W, Zhang C, Rickner H, Richmond CA, Li H, Breault DT, Ingber DE. Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids. Scientific Reports. 8: 2871. PMID 29440725 DOI: 10.1038/S41598-018-21201-7  0.343
2018 De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R. PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 29343648 DOI: 10.1073/Pnas.1718600115  0.306
2018 Prantil-Baun R, Novak R, Das D, Somayaji MR, Przekwas A, Ingber DE. Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips. Annual Review of Pharmacology and Toxicology. 58: 37-64. PMID 29309256 DOI: 10.1146/Annurev-Pharmtox-010716-104748  0.344
2018 Goyal G, Long J, Ingber DE. Abstract A76: Microenginered human lymphoid tissue on chip Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-A76  0.392
2018 Reilly CB, Ingber DE. Multi-scale modeling reveals use of hierarchical tensegrity principles at the molecular, multi-molecular, and cellular levels Extreme Mechanics Letters. 20: 21-28. DOI: 10.1016/J.Eml.2018.01.001  0.346
2017 Musah S, Mammoto A, Ferrante TC, Jeanty SSF, Hirano-Kobayashi M, Mammoto T, Roberts K, Chung S, Novak R, Ingram M, Fatanat-Didar T, Koshy S, Weaver JC, Church GM, Ingber DE. Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. Nature Biomedical Engineering. 1. PMID 29038743 DOI: 10.1038/S41551-017-0069  0.78
2017 Hassell BA, Goyal G, Lee E, Sontheimer-Phelps A, Levy O, Chen CS, Ingber DE. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Reports. 21: 508-516. PMID 29020635 DOI: 10.1016/J.Celrep.2017.09.043  0.794
2017 Hashmi B, Mammoto T, Weaver J, Ferrante T, Jiang A, Jiang E, Feliz J, Ingber DE. Mechanical induction of dentin-like differentiation by adult mouse bone marrow stromal cells using compressive scaffolds. Stem Cell Research. 24: 55-60. PMID 28841424 DOI: 10.1016/J.Scr.2017.08.011  0.38
2017 Benam KH, Mazur M, Choe Y, Ferrante TC, Novak R, Ingber DE. Human Lung Small Airway-on-a-Chip Protocol. Methods in Molecular Biology (Clifton, N.J.). 1612: 345-365. PMID 28634955 DOI: 10.1007/978-1-4939-7021-6_25  0.373
2017 Maoz BM, Herland A, Henry OYF, Leineweber WD, Yadid M, Doyle J, Mannix R, Kujala VJ, FitzGerald EA, Parker KK, Ingber DE. Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities. Lab On a Chip. PMID 28608907 DOI: 10.1039/C7Lc00412E  0.559
2017 Henry OYF, Villenave R, Cronce MJ, Leineweber WD, Benz MA, Ingber DE. Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function. Lab On a Chip. PMID 28598479 DOI: 10.1039/C7Lc00155J  0.344
2017 Jain A, Barrile R, van der Meer AD, Mammoto A, Mammoto T, De Ceunynck K, Aisiku O, Otieno MA, Louden CS, Hamilton GA, Flaumenhaft R, Ingber DE. A primary human lung alveolus-on-a-chip model of intravascular thrombosis for assessment of therapeutics. Clinical Pharmacology and Therapeutics. PMID 28516446 DOI: 10.1002/Cpt.742  0.327
2017 Villenave R, Wales SQ, Hamkins-Indik T, Papafragkou E, Weaver JC, Ferrante TC, Bahinski A, Elkins CA, Kulka M, Ingber DE. Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro. Plos One. 12: e0169412. PMID 28146569 DOI: 10.1371/Journal.Pone.0169412  0.313
2016 Benam KH, Novak R, Nawroth J, Hirano-Kobayashi M, Ferrante TC, Choe Y, Prantil-Baun R, Weaver JC, Bahinski A, Parker KK, Ingber DE. Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip. Cell Systems. 3: 456-466.e4. PMID 27894999 DOI: 10.1016/J.Cels.2016.10.003  0.516
2016 Kim HJ, Lee J, Choi JH, Bahinski A, Ingber DE. Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device. Journal of Visualized Experiments : Jove. PMID 27684630 DOI: 10.3791/54344  0.466
2016 Torisawa YS, Mammoto T, Jiang E, Jiang A, Mammoto A, Watters AL, Bahinski A, Ingber D. Modeling hematopoiesis and responses to radiation countermeasures in a bone marrow-on-a-chip. Tissue Engineering. Part C, Methods. PMID 26993746 DOI: 10.1089/Ten.Tec.2015.0507  0.301
2016 Ingber DE. Reverse Engineering Human Pathophysiology with Organs-on-Chips. Cell. 164: 1105-9. PMID 26967278 DOI: 10.1016/J.Cell.2016.02.049  0.334
2016 Herland A, van der Meer AD, FitzGerald EA, Park TE, Sleeboom JJ, Ingber DE. Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip. Plos One. 11: e0150360. PMID 26930059 DOI: 10.1371/Journal.Pone.0150360  0.348
2016 Benam KH, Novak R, Villenave R, Lucchesi C, Hubeau C, Nawroth J, Hirano-Kobayashi M, Ferrante TC, Choe Y, Prantil-Baun R, Weaver JC, Hamilton GA, Bahinski A, Ingber DE. Human small airway-on-a-chip: A novel microphysiological system to model lung inflammation, accelerate drug development and enable inhalational toxico-analysis European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa4542  0.302
2016 Goyal G, Ingber D. Abstract B102: A microengineered human lymph node-on-a-chip to study cancer immunotherapy Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B102  0.338
2015 Benam KH, Villenave R, Lucchesi C, Varone A, Hubeau C, Lee HH, Alves SE, Salmon M, Ferrante TC, Weaver JC, Bahinski A, Hamilton GA, Ingber DE. Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro. Nature Methods. PMID 26689262 DOI: 10.1038/Nmeth.3697  0.311
2015 Kim HJ, Li H, Collins JJ, Ingber DE. Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip. Proceedings of the National Academy of Sciences of the United States of America. PMID 26668389 DOI: 10.1073/Pnas.1522193112  0.446
2015 Huebsch N, Lippens E, Lee K, Mehta M, Koshy ST, Darnell MC, Desai RM, Madl CM, Xu M, Zhao X, Chaudhuri O, Verbeke C, Kim WS, Alim K, Mammoto A, ... Ingber DE, et al. Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation. Nature Materials. PMID 26366848 DOI: 10.1038/Nmat4407  0.35
2015 Brock A, Krause S, Ingber DE. Control of cancer formation by intrinsic genetic noise and microenvironmental cues. Nature Reviews. Cancer. 15: 499-509. PMID 26156637 DOI: 10.1038/Nrc3959  0.644
2015 Mammoto T, Chen Z, Jiang A, Jiang E, Ingber DE, Mammoto A. Platelet-rich Plasma Extract Accelerates Lung Regeneration Through the LRP5-Tie2 Pathway. American Journal of Respiratory Cell and Molecular Biology. PMID 26091161 DOI: 10.1165/Rcmb.2015-0045Oc  0.303
2015 Diaz MF, Li N, Lee HJ, Adamo L, Evans SM, Willey HE, Arora N, Torisawa YS, Vickers DA, Morris SA, Naveiras O, Murthy SK, Ingber DE, Daley GQ, García-Cardeña G, et al. Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis. The Journal of Experimental Medicine. 212: 665-80. PMID 25870199 DOI: 10.1085/Jgp.1455Oia20  0.321
2015 Adapala RK, Thoppil RJ, Ghosh K, Cappelli HC, Dudley AC, Paruchuri S, Keshamouni V, Klagsbrun M, Meszaros JG, Chilian WM, Ingber DE, Thodeti CK. Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. Oncogene. PMID 25867067 DOI: 10.1038/Onc.2015.83  0.306
2015 Mammoto T, Mammoto A, Jiang A, Jiang E, Hashmi B, Ingber DE. Mesenchymal condensation-dependent accumulation of collagen VI stabilizes organ-specific cell fates during embryonic tooth formation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 244: 713-23. PMID 25715693 DOI: 10.1002/Dvdy.24264  0.4
2015 Lucio AA, Ingber DE, Campàs O. Generation of biocompatible droplets for in vivo and in vitro measurement of cell-generated mechanical stresses. Methods in Cell Biology. 125: 373-90. PMID 25640439 DOI: 10.1016/Bs.Mcb.2014.11.008  0.349
2015 Benam KH, Dauth S, Hassell B, Herland A, Jain A, Jang KJ, Karalis K, Kim HJ, MacQueen L, Mahmoodian R, Musah S, Torisawa YS, van der Meer AD, Villenave R, Yadid M, ... ... Ingber DE, et al. Engineered in vitro disease models. Annual Review of Pathology. 10: 195-262. PMID 25621660 DOI: 10.1146/Annurev-Pathol-012414-040418  0.794
2015 Odijk M, van der Meer AD, Levner D, Kim HJ, van der Helm MW, Segerink LI, Frimat JP, Hamilton GA, Ingber DE, van den Berg A. Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems. Lab On a Chip. 15: 745-52. PMID 25427650 DOI: 10.1039/C4Lc01219D  0.438
2014 Bhatia SN, Ingber DE. Microfluidic organs-on-chips. Nature Biotechnology. 32: 760-72. PMID 25093883 DOI: 10.1038/Nbt.2989  0.357
2014 Shemesh J, Ben Arye T, Avesar J, Kang JH, Fine A, Super M, Meller A, Ingber DE, Levenberg S. Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis. Proceedings of the National Academy of Sciences of the United States of America. 111: 11293-8. PMID 25053808 DOI: 10.1073/Pnas.1404472111  0.378
2014 Yang Z, Liu Q, Mannix RJ, Xu X, Li H, Ma Z, Ingber DE, Allen PD, Wang Y. Mononuclear cells from dedifferentiation of mouse myotubes display remarkable regenerative capability. Stem Cells (Dayton, Ohio). 32: 2492-501. PMID 24916688 DOI: 10.1002/Stem.1742  0.328
2014 Kanapathipillai M, Brock A, Ingber DE. Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment. Advanced Drug Delivery Reviews. 79: 107-18. PMID 24819216 DOI: 10.1016/J.Addr.2014.05.005  0.594
2014 Ingber DE, Wang N, Stamenovic D. Tensegrity, cellular biophysics, and the mechanics of living systems. Reports On Progress in Physics. Physical Society (Great Britain). 77: 046603. PMID 24695087 DOI: 10.1088/0034-4885/77/4/046603  0.401
2014 Polacheck WJ, German AE, Mammoto A, Ingber DE, Kamm RD. Mechanotransduction of fluid stresses governs 3D cell migration. Proceedings of the National Academy of Sciences of the United States of America. 111: 2447-52. PMID 24550267 DOI: 10.1073/Pnas.1316848111  0.396
2014 Hashmi B, Zarzar LD, Mammoto T, Mammoto A, Jiang A, Aizenberg J, Ingber DE. Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation. Advanced Materials (Deerfield Beach, Fla.). 26: 3253-7. PMID 24550068 DOI: 10.1002/Adma.201304995  0.328
2014 German AE, Mammoto T, Jiang E, Ingber DE, Mammoto A. Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression. Journal of Cell Science. 127: 1672-83. PMID 24522185 DOI: 10.1242/Jcs.132316  0.347
2014 Dolatshahi-Pirouz A, Nikkhah M, Gaharwar AK, Hashmi B, Guermani E, Aliabadi H, Camci-Unal G, Ferrante T, Foss M, Ingber DE, Khademhosseini A. A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells. Scientific Reports. 4: 3896. PMID 24473466 DOI: 10.1038/Srep03896  0.369
2014 Brock A, Krause S, Li H, Kowalski M, Goldberg MS, Collins JJ, Ingber DE. Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice. Science Translational Medicine. 6: 217ra2. PMID 24382894 DOI: 10.1126/Scitranslmed.3007048  0.618
2014 Campàs O, Mammoto T, Hasso S, Sperling RA, O'Connell D, Bischof AG, Maas R, Weitz DA, Mahadevan L, Ingber DE. Quantifying cell-generated mechanical forces within living embryonic tissues. Nature Methods. 11: 183-9. PMID 24317254 DOI: 10.1038/Nmeth.2761  0.52
2014 Campàs O, Mammoto T, Hasso S, Sperling RA, O'Connell D, Bischof AG, Maas R, Weitz DA, Mahadevan L, Ingber DE. Corrigendum: Quantifying cell-generated mechanical forces within living embryonic tissues Nature Methods. 11: 349. DOI: 10.1038/Nmeth0314-349D  0.437
2013 Krause S, Brock A, Ingber DE. Intraductal injection for localized drug delivery to the mouse mammary gland. Journal of Visualized Experiments : Jove. PMID 24121742 DOI: 10.3791/50692  0.586
2013 Huh D, Kim HJ, Fraser JP, Shea DE, Khan M, Bahinski A, Hamilton GA, Ingber DE. Microfabrication of human organs-on-chips. Nature Protocols. 8: 2135-57. PMID 24113786 DOI: 10.1038/Nprot.2013.137  0.498
2013 Mammoto T, Mammoto A, Ingber DE. Mechanobiology and developmental control. Annual Review of Cell and Developmental Biology. 29: 27-61. PMID 24099083 DOI: 10.1146/Annurev-Cellbio-101512-122340  0.358
2013 Werfel J, Krause S, Bischof AG, Mannix RJ, Tobin H, Bar-Yam Y, Bellin RM, Ingber DE. How changes in extracellular matrix mechanics and gene expression variability might combine to drive cancer progression. Plos One. 8: e76122. PMID 24098430 DOI: 10.1371/Journal.Pone.0076122  0.381
2013 Deiss F, Mazzeo A, Hong E, Ingber DE, Derda R, Whitesides GM. Platform for high-throughput testing of the effect of soluble compounds on 3D cell cultures. Analytical Chemistry. 85: 8085-94. PMID 23952342 DOI: 10.1021/Ac400161J  0.681
2013 Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, ... ... Ingber DE, et al. Epoxyeicosanoids promote organ and tissue regeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: 13528-33. PMID 23898174 DOI: 10.1073/Pnas.1311565110  0.674
2013 Kim HJ, Ingber DE. Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1130-40. PMID 23817533 DOI: 10.1039/C3Ib40126J  0.498
2013 Bischof AG, Yüksel D, Mammoto T, Mammoto A, Krause S, Ingber DE. Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1045-56. PMID 23817524 DOI: 10.1039/C3Ib40103K  0.338
2013 Gee EP, Yüksel D, Stultz CM, Ingber DE. SLLISWD sequence in the 10FNIII domain initiates fibronectin fibrillogenesis. The Journal of Biological Chemistry. 288: 21329-40. PMID 23740248 DOI: 10.1074/Jbc.M113.462077  0.308
2013 Jang KJ, Mehr AP, Hamilton GA, McPartlin LA, Chung S, Suh KY, Ingber DE. Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1119-29. PMID 23644926 DOI: 10.1039/C3Ib40049B  0.374
2013 Wälchli T, Pernet V, Weinmann O, Shiu JY, Guzik-Kornacka A, Decrey G, Yüksel D, Schneider H, Vogel J, Ingber DE, Vogel V, Frei K, Schwab ME. Nogo-A is a negative regulator of CNS angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: E1943-52. PMID 23625008 DOI: 10.1073/Pnas.1216203110  0.33
2013 Mammoto A, Mammoto T, Kanapathipillai M, Wing Yung C, Jiang E, Jiang A, Lofgren K, Gee EP, Ingber DE. Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. Nature Communications. 4: 1759. PMID 23612300 DOI: 10.1038/Ncomms2774  0.675
2013 Krause S, Brock A, Goldberg M, Ingber DE. Abstract 2025: Prevention of mammary tumor progression via intraductal injection of nanoparticle-formulated siRNA. Cancer Research. 73: 2025-2025. DOI: 10.1158/1538-7445.Am2013-2025  0.601
2013 Deiss F, Mazzeo A, Hong E, Ingber DE, Derda R, Whitesides GM. Cells in gels in paper in a new device Assay and Drug Development Technologies. 11: 512-514. DOI: 10.1089/Adt.2013.1109.Lr  0.629
2012 Huh D, Leslie DC, Matthews BD, Fraser JP, Jurek S, Hamilton GA, Thorneloe KS, McAlexander MA, Ingber DE. A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Science Translational Medicine. 4: 159ra147. PMID 23136042 DOI: 10.1126/Scitranslmed.3004249  0.35
2012 Sero JE, German AE, Mammoto A, Ingber DE. Paxillin controls directional cell motility in response to physical cues. Cell Adhesion & Migration. 6: 502-8. PMID 23076140 DOI: 10.4161/Cam.21672  0.781
2012 Kim SB, Koo KI, Bae H, Dokmeci MR, Hamilton GA, Bahinski A, Kim SM, Ingber DE, Khademhosseini A. A mini-microscope for in situ monitoring of cells. Lab On a Chip. 12: 3976-82. PMID 22911426 DOI: 10.1039/C2Lc40345E  0.34
2012 Mammoto A, Mammoto T, Ingber DE. Mechanosensitive mechanisms in transcriptional regulation. Journal of Cell Science. 125: 3061-73. PMID 22797927 DOI: 10.1242/Jcs.093005  0.371
2012 Ingber DE, Whitesides GM. Lab on a chip: United States of America. Lab On a Chip. 12: 2089-90. PMID 22588356 DOI: 10.1039/C2Lc90052A  0.333
2012 Huh D, Torisawa YS, Hamilton GA, Kim HJ, Ingber DE. Microengineered physiological biomimicry: organs-on-chips. Lab On a Chip. 12: 2156-64. PMID 22555377 DOI: 10.1039/C2Lc40089H  0.479
2012 Kanapathipillai M, Mammoto A, Mammoto T, Kang JH, Jiang E, Ghosh K, Korin N, Gibbs A, Mannix R, Ingber DE. Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. Nano Letters. 12: 3213-7. PMID 22554317 DOI: 10.1021/Nl301206P  0.302
2012 Kang JH, Krause S, Tobin H, Mammoto A, Kanapathipillai M, Ingber DE. A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells. Lab On a Chip. 12: 2175-81. PMID 22453808 DOI: 10.1039/C2Lc40072C  0.351
2012 Kim HJ, Huh D, Hamilton G, Ingber DE. Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab On a Chip. 12: 2165-74. PMID 22434367 DOI: 10.1039/C2Lc40074J  0.475
2012 O'Connell DJ, Ho JW, Mammoto T, Turbe-Doan A, O'Connell JT, Haseley PS, Koo S, Kamiya N, Ingber DE, Park PJ, Maas RL. A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis. Science Signaling. 5: ra4. PMID 22234613 DOI: 10.1126/Scisignal.2002414  0.305
2012 Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, ... ... Ingber DE, et al. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. The Journal of Clinical Investigation. 122: 178-91. PMID 22182838 DOI: 10.1172/Jci58128  0.662
2012 Brock A, Li H, Krause S, Kowalski M, Collins JJ, Ingber DE. Abstract 4920: Gene network models identify targets for mammary tumor normalization Cancer Research. 72: 4920-4920. DOI: 10.1158/1538-7445.Am2012-4920  0.638
2012 Brock A, Krause S, Li H, Kowalski M, Collins J, Ingber D. Abstract P5-05-04: Intraductal delivery of RNAi-based therapeutics to gene targets identified through computational systems modeling Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P5-05-04  0.576
2011 Sero JE, Thodeti CK, Mammoto A, Bakal C, Thomas S, Ingber DE. Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning. Plos One. 6: e28303. PMID 22194823 DOI: 10.1371/Journal.Pone.0028303  0.778
2011 Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, Klagsbrun M, Lim S, Moses MA, Zetter B, Dvorak H, Langer R. Forty-year journey of angiogenesis translational research. Science Translational Medicine. 3: 114rv3. PMID 22190240 DOI: 10.1126/Scitranslmed.3003149  0.732
2011 Huh D, Hamilton GA, Ingber DE. From 3D cell culture to organs-on-chips. Trends in Cell Biology. 21: 745-54. PMID 22033488 DOI: 10.1016/J.Tcb.2011.09.005  0.369
2011 Mammoto T, Mammoto A, Torisawa YS, Tat T, Gibbs A, Derda R, Mannix R, de Bruijn M, Yung CW, Huh D, Ingber DE. Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. Developmental Cell. 21: 758-69. PMID 21924961 DOI: 10.1016/J.Devcel.2011.07.006  0.68
2011 Ingber DE. The Wyss Institute at Harvard University. Ieee Pulse. 2: 43-6. PMID 21791399 DOI: 10.1109/Mpul.2011.941455  0.322
2011 Derda R, Tang SK, Laromaine A, Mosadegh B, Hong E, Mwangi M, Mammoto A, Ingber DE, Whitesides GM. Multizone paper platform for 3D cell cultures. Plos One. 6: e18940. PMID 21573103 DOI: 10.1371/Journal.Pone.0018940  0.685
2011 Krause S, Tobin H, Brock A, Ingber DE. Abstract 520: Local changes in tissue microenvironment regulate mammary tumor progression Cancer Research. 71: 520-520. DOI: 10.1158/1538-7445.Am2011-520  0.628
2011 Brock A, Li H, Krause S, Collins JJ, Ingber DE. Abstract 4924: Gene network inference models reveal novel key mediators of mammary tumorigenesis Cancer Research. 71: 4924-4924. DOI: 10.1158/1538-7445.Am2011-4924  0.617
2011 Ingber D. Mechanotransduction and Developmental Control Biophysical Journal. 100: 523a. DOI: 10.1016/J.Bpj.2010.12.3060  0.332
2011 Ingber DE. Extracellular Matrix: A Solid-State Regulator of Cell form, Function, and Tissue Development Comprehensive Physiology. 541-556. DOI: 10.1002/Cphy.Cp140112  0.35
2010 Xu Y, Bismar TA, Su J, Xu B, Kristiansen G, Varga Z, Teng L, Ingber DE, Mammoto A, Kumar R, Alaoui-Jamali MA. Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. The Journal of Experimental Medicine. 207: 2421-37. PMID 20937704 DOI: 10.1084/Jem.20100433  0.31
2010 Matthews BD, Thodeti CK, Tytell JD, Mammoto A, Overby DR, Ingber DE. Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integrative Biology : Quantitative Biosciences From Nano to Macro. 2: 435-42. PMID 20725677 DOI: 10.1039/C0Ib00034E  0.351
2010 Huh D, Matthews BD, Mammoto A, Montoya-Zavala M, Hsin HY, Ingber DE. Reconstituting organ-level lung functions on a chip. Science (New York, N.Y.). 328: 1662-8. PMID 20576885 DOI: 10.1126/Science.1188302  0.325
2010 Mammoto T, Ingber DE. Mechanical control of tissue and organ development. Development (Cambridge, England). 137: 1407-20. PMID 20388652 DOI: 10.1242/Dev.024166  0.33
2010 Ingber DE. From cellular mechanotransduction to biologically inspired engineering: 2009 Pritzker Award Lecture, BMES Annual Meeting October 10, 2009. Annals of Biomedical Engineering. 38: 1148-61. PMID 20140519 DOI: 10.1007/S10439-010-9946-0  0.394
2010 Bracha AL, Ramanathan A, Huang S, Ingber DE, Schreiber SL. Carbon metabolism-mediated myogenic differentiation. Nature Chemical Biology. 6: 202-204. PMID 20081855 DOI: 10.1038/Nchembio.301  0.759
2010 Fainaru O, Almog N, Yung CW, Nakai K, Montoya-Zavala M, Abdollahi A, D'Amato R, Ingber DE. Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1411-8. PMID 20008545 DOI: 10.1096/Fj.09-147025  0.644
2010 Friedsam C, Ingber DE, Weitz DA, Sahin O. Mapping Elasticity Down to the Molecular Scale: a Novel High-Resolution Approach to Study Cell Mechanics Biophysical Journal. 98: 368a-369a. DOI: 10.1016/J.Bpj.2009.12.1987  0.492
2009 Derda R, Laromaine A, Mammoto A, Tang SK, Mammoto T, Ingber DE, Whitesides GM. Paper-supported 3D cell culture for tissue-based bioassays. Proceedings of the National Academy of Sciences of the United States of America. 106: 18457-62. PMID 19846768 DOI: 10.1073/Pnas.0910666106  0.703
2009 Mammoto A, Ingber DE. Cytoskeletal control of growth and cell fate switching. Current Opinion in Cell Biology. 21: 864-70. PMID 19740640 DOI: 10.1016/J.Ceb.2009.08.001  0.414
2009 Czakó B, Kürti L, Mammoto A, Ingber DE, Corey EJ. Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. Journal of the American Chemical Society. 131: 9014-9. PMID 19469509 DOI: 10.1021/Ja902601E  0.33
2009 Thodeti CK, Matthews B, Ravi A, Mammoto A, Ghosh K, Bracha AL, Ingber DE. TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circulation Research. 104: 1123-30. PMID 19359599 DOI: 10.1161/Circresaha.108.192930  0.79
2009 Discher D, Dong C, Fredberg JJ, Guilak F, Ingber D, Janmey P, Kamm RD, Schmid-Schönbein GW, Weinbaum S. Biomechanics: cell research and applications for the next decade. Annals of Biomedical Engineering. 37: 847-59. PMID 19259817 DOI: 10.1007/S10439-009-9661-X  0.328
2009 Ostuni E, Whitesides GM, Ingber DE, Chen CS. Using self-assembled monolayers to pattern ECM proteins and cells on substrates. Methods in Molecular Biology (Clifton, N.J.). 522: 183-94. PMID 19247618 DOI: 10.1007/978-1-59745-413-1_12  0.677
2009 Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE. A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature. 457: 1103-8. PMID 19242469 DOI: 10.1038/Nature07765  0.352
2009 Wang N, Tytell JD, Ingber DE. Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nature Reviews. Molecular Cell Biology. 10: 75-82. PMID 19197334 DOI: 10.1038/Nrm2594  0.33
2009 Alenghat FJ, Tytell JD, Thodeti CK, Derrien A, Ingber DE. Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein. Journal of Cellular Biochemistry. 106: 529-38. PMID 19170051 DOI: 10.1002/Jcb.22001  0.702
2009 Stamenovi? D, Ingber DE. Tensegrity-guided self assembly: From molecules to living cells Soft Matter. 5: 1137-1145. DOI: 10.1039/B806442C  0.369
2009 Adams WJ, O'Grady ML, Ghosh K, Gibbs AD, Geisse NA, Ingber DE, Parker KK. Viscoelastic Indentation of Extremely Soft Biological Samples Biophysical Journal. 96: 398a. DOI: 10.1016/J.Bpj.2008.12.2026  0.542
2008 Ingber DE. Tensegrity and mechanotransduction. Journal of Bodywork and Movement Therapies. 12: 198-200. PMID 19083675 DOI: 10.1016/J.Jbmt.2008.04.038  0.372
2008 Gee EP, Ingber DE, Stultz CM. Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat. Plos One. 3: e2373. PMID 19020673 DOI: 10.1371/Journal.Pone.0002373  0.37
2008 Mammoto A, Sero JE, Mammoto T, Ingber DE. Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. Methods in Enzymology. 443: 227-59. PMID 18772019 DOI: 10.1016/S0076-6879(08)02012-0  0.76
2008 Hoffmann M, Chang HH, Huang S, Ingber DE, Loeffler M, Galle J. Noise-driven stem cell and progenitor population dynamics. Plos One. 3: e2922. PMID 18698344 DOI: 10.1371/Journal.Pone.0002922  0.661
2008 Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE. Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proceedings of the National Academy of Sciences of the United States of America. 105: 11305-10. PMID 18685096 DOI: 10.1073/Pnas.0800835105  0.379
2008 Shimizu A, Mammoto A, Italiano JE, Pravda E, Dudley AC, Ingber DE, Klagsbrun M. ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. The Journal of Biological Chemistry. 283: 27230-8. PMID 18660502 DOI: 10.1074/Jbc.M804520200  0.369
2008 Mannix RJ, Kumar S, Cassiola F, Montoya-Zavala M, Feinstein E, Prentiss M, Ingber DE. Nanomagnetic actuation of receptor-mediated signal transduction. Nature Nanotechnology. 3: 36-40. PMID 18654448 DOI: 10.1038/Nnano.2007.418  0.321
2008 Chang HH, Hemberg M, Barahona M, Ingber DE, Huang S. Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature. 453: 544-7. PMID 18497826 DOI: 10.1038/Nature06965  0.694
2008 Ingber DE. Can cancer be reversed by engineering the tumor microenvironment? Seminars in Cancer Biology. 18: 356-64. PMID 18472275 DOI: 10.1016/J.Semcancer.2008.03.016  0.369
2008 Ingber DE. Tensegrity-based mechanosensing from macro to micro. Progress in Biophysics and Molecular Biology. 97: 163-79. PMID 18406455 DOI: 10.1016/J.Pbiomolbio.2008.02.005  0.391
2008 Mammoto A, Mammoto T, Ingber DE. Rho signaling and mechanical control of vascular development. Current Opinion in Hematology. 15: 228-34. PMID 18391790 DOI: 10.1097/Moh.0B013E3282Fa7445  0.409
2008 Lele TP, Thodeti CK, Pendse J, Ingber DE. Investigating complexity of protein-protein interactions in focal adhesions. Biochemical and Biophysical Research Communications. 369: 929-34. PMID 18331831 DOI: 10.1016/J.Bbrc.2008.02.137  0.34
2008 Nauli SM, Kawanabe Y, Kaminski JJ, Pearce WJ, Ingber DE, Zhou J. Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1. Circulation. 117: 1161-71. PMID 18285569 DOI: 10.1161/Circulationaha.107.710111  0.314
2008 Xia N, Thodeti CK, Hunt TP, Xu Q, Ho M, Whitesides GM, Westervelt R, Ingber DE. Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1649-59. PMID 18180334 DOI: 10.1096/Fj.07-090571  0.528
2008 Ezzell RM, Goldmann WH, Wang N, Parashurama N, Ingber DE. Corrigendum to "Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton" [Exp. Cell Res. 231 (1997) 14-26] (DOI:10.1006/excr.1996.3451) Experimental Cell Research. 314: 2163. DOI: 10.1016/J.Yexcr.2008.02.017  0.387
2008 Chen CS, Ingber DE. Tensegrity and mechanoregulation: From skeleton to cytoskeleton | Tensegrity und mechanoregulation: Vom skelett zum zytoskelett Osteopathische Medizin. 9: 4-17. DOI: 10.1016/J.Ostmed.2008.09.010  0.485
2008 Ingber DE. From Molecular Cell Engineering to Biologically Inspired Engineering Cellular and Molecular Bioengineering. 1: 51-57. DOI: 10.1007/S12195-008-0006-X  0.371
2007 Pietramaggiori G, Liu P, Scherer SS, Kaipainen A, Prsa MJ, Mayer H, Newalder J, Alperovich M, Mentzer SJ, Konerding MA, Huang S, Ingber DE, Orgill DP. Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin. Annals of Surgery. 246: 896-902. PMID 17968184 DOI: 10.1097/Sla.0B013E3180Caa47F  0.583
2007 Ghosh K, Ingber DE. Micromechanical control of cell and tissue development: implications for tissue engineering. Advanced Drug Delivery Reviews. 59: 1306-18. PMID 17920155 DOI: 10.1016/J.Addr.2007.08.014  0.367
2007 Stamenovi? D, Rosenblatt N, Montoya-Zavala M, Matthews BD, Hu S, Suki B, Wang N, Ingber DE. Rheological behavior of living cells is timescale-dependent. Biophysical Journal. 93: L39-41. PMID 17693464 DOI: 10.1529/Biophysj.107.116582  0.357
2007 Lele TP, Sero JE, Matthews BD, Kumar S, Xia S, Montoya-Zavala M, Polte T, Overby D, Wang N, Ingber DE. Tools to study cell mechanics and mechanotransduction. Methods in Cell Biology. 83: 443-72. PMID 17613320 DOI: 10.1016/S0091-679X(07)83019-6  0.769
2007 Parker KK, Ingber DE. Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 362: 1267-79. PMID 17588874 DOI: 10.1098/Rstb.2007.2114  0.554
2007 Ingber DE, Levin M. What lies at the interface of regenerative medicine and developmental biology? Development (Cambridge, England). 134: 2541-7. PMID 17553905 DOI: 10.1242/Dev.003707  0.323
2007 Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, Adelstein RS, Ingber D, Daley GQ, Shivdasani RA. The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood. 110: 171-9. PMID 17392504 DOI: 10.1182/Blood-2007-02-071589  0.324
2007 Polte TR, Shen M, Karavitis J, Montoya M, Pendse J, Xia S, Mazur E, Ingber DE. Nanostructured magnetizable materials that switch cells between life and death. Biomaterials. 28: 2783-90. PMID 17339050 DOI: 10.1016/J.Biomaterials.2007.01.045  0.375
2007 Mammoto A, Huang S, Ingber DE. Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. Journal of Cell Science. 120: 456-67. PMID 17227794 DOI: 10.1242/Jcs.03353  0.61
2007 Joy MP, Ingber DE, Huang S. Chaotic mean field dynamics of a Boolean network with random connectivity International Journal of Modern Physics C. 18: 1459-1473. DOI: 10.1142/S0129183107011467  0.492
2007 Matthews BD, Thodeti CK, Ingber DE. Activation of Mechanosensitive Ion Channels by Forces Transmitted Through Integrins and the Cytoskeleton Current Topics in Membranes. 58: 59-85. DOI: 10.1016/S1063-5823(06)58003-2  0.312
2006 Alsberg E, Feinstein E, Joy MP, Prentiss M, Ingber DE. Magnetically-guided self-assembly of fibrin matrices with ordered nano-scale structure for tissue engineering. Tissue Engineering. 12: 3247-56. PMID 17518638 DOI: 10.1089/Ten.2006.12.3247  0.367
2006 Guo Y, Eichler GS, Feng Y, Ingber DE, Huang S. Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers. Journal of Biomedicine & Biotechnology. 2006: 69141. PMID 17489018 DOI: 10.1155/Jbb/2006/69141  0.538
2006 Huang S, Ingber DE. A non-genetic basis for cancer progression and metastasis: self-organizing attractors in cell regulatory networks. Breast Disease. 26: 27-54. PMID 17473364 DOI: 10.3233/Bd-2007-26104  0.571
2006 Xia N, Hunt TP, Mayers BT, Alsberg E, Whitesides GM, Westervelt RM, Ingber DE. Combined microfluidic-micromagnetic separation of living cells in continuous flow. Biomedical Microdevices. 8: 299-308. PMID 17003962 DOI: 10.1007/S10544-006-0033-0  0.413
2006 Yokouchi K, Numaguchi Y, Kubota R, Ishii M, Imai H, Murakami R, Ogawa Y, Kondo T, Okumura K, Ingber DE, Murohara T. l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2231-7. PMID 16888241 DOI: 10.1161/01.Atv.0000239441.29687.97  0.327
2006 Brangwynne CP, MacKintosh FC, Kumar S, Geisse NA, Talbot J, Mahadevan L, Parker KK, Ingber DE, Weitz DA. Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. The Journal of Cell Biology. 173: 733-41. PMID 16754957 DOI: 10.1083/Jcb.200601060  0.621
2006 Ingber DE. Cellular mechanotransduction: putting all the pieces together again. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 811-27. PMID 16675838 DOI: 10.1096/Fj.05-5424Rev  0.387
2006 Nauli SM, Rossetti S, Kolb RJ, Alenghat FJ, Consugar MB, Harris PC, Ingber DE, Loghman-Adham M, Zhou J. Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. Journal of the American Society of Nephrology : Jasn. 17: 1015-25. PMID 16565258 DOI: 10.1681/Asn.2005080830  0.691
2006 Chang HH, Oh PY, Ingber DE, Huang S. Multistable and multistep dynamics in neutrophil differentiation. Bmc Cell Biology. 7: 11. PMID 16507101 DOI: 10.1186/1471-2121-7-11  0.699
2006 Kumar S, Maxwell IZ, Heisterkamp A, Polte TR, Lele TP, Salanga M, Mazur E, Ingber DE. Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophysical Journal. 90: 3762-73. PMID 16500961 DOI: 10.1529/Biophysj.105.071506  0.362
2006 Ingber DE. Mechanical control of tissue morphogenesis during embryological development. The International Journal of Developmental Biology. 50: 255-66. PMID 16479493 DOI: 10.1387/Ijdb.052044Di  0.439
2006 Matthews BD, Overby DR, Mannix R, Ingber DE. Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. Journal of Cell Science. 119: 508-18. PMID 16443749 DOI: 10.1242/Jcs.02760  0.341
2006 Lele TP, Thodeti CK, Ingber DE. Force meets chemistry: analysis of mechanochemical conversion in focal adhesions using fluorescence recovery after photobleaching. Journal of Cellular Biochemistry. 97: 1175-83. PMID 16408278 DOI: 10.1002/Jcb.20761  0.382
2006 Lele TP, Pendse J, Kumar S, Salanga M, Karavitis J, Ingber DE. Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. Journal of Cellular Physiology. 207: 187-94. PMID 16288479 DOI: 10.1002/Jcp.20550  0.359
2005 Brock AL, Ingber DE. Control of the direction of lamellipodia extension through changes in the balance between Rac and Rho activities. Molecular & Cellular Biomechanics : McB. 2: 135-43. PMID 16708475  0.314
2005 Shen N, Datta D, Schaffer CB, LeDuc P, Ingber DE, Mazur E. Ablation of cytoskeletal filaments and mitochondria in live cells using a femtosecond laser nanoscissor. Mechanics & Chemistry of Biosystems : McB. 2: 17-25. PMID 16708469  0.668
2005 Overby DR, Matthews BD, Alsberg E, Ingber DE. Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry. Acta Biomaterialia. 1: 295-303. PMID 16701808 DOI: 10.1016/J.Actbio.2005.02.003  0.371
2005 Barnés CM, Huang S, Kaipainen A, Sanoudou D, Chen EJ, Eichler GS, Guo Y, Yu Y, Ingber DE, Mulliken JB, Beggs AH, Folkman J, Fishman SJ. Evidence by molecular profiling for a placental origin of infantile hemangioma. Proceedings of the National Academy of Sciences of the United States of America. 102: 19097-102. PMID 16365311 DOI: 10.1073/Pnas.0509579102  0.569
2005 Alon R, Feigelson SW, Manevich E, Rose DM, Schmitz J, Overby DR, Winter E, Grabovsky V, Shinder V, Matthews BD, Sokolovsky-Eisenberg M, Ingber DE, Benoit M, Ginsberg MH. Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain. The Journal of Cell Biology. 171: 1073-84. PMID 16365170 DOI: 10.1083/Jcb.200503155  0.301
2005 Huang S, Ingber DE. Cell tension, matrix mechanics, and cancer development. Cancer Cell. 8: 175-6. PMID 16169461 DOI: 10.1016/J.Ccr.2005.08.009  0.577
2005 Ingber DE. Mechanical control of tissue growth: function follows form. Proceedings of the National Academy of Sciences of the United States of America. 102: 11571-2. PMID 16091458 DOI: 10.1073/Pnas.0505939102  0.307
2005 Joy MP, Brock A, Ingber DE, Huang S. High-betweenness proteins in the yeast protein interaction network. Journal of Biomedicine & Biotechnology. 2005: 96-103. PMID 16046814 DOI: 10.1155/Jbb.2005.96  0.674
2005 Huang S, Brangwynne CP, Parker KK, Ingber DE. Symmetry-breaking in mammalian cell cohort migration during tissue pattern formation: role of random-walk persistence. Cell Motility and the Cytoskeleton. 61: 201-13. PMID 15986404 DOI: 10.1002/Cm.20077  0.726
2005 Huang S, Eichler G, Bar-Yam Y, Ingber DE. Cell fates as high-dimensional attractor states of a complex gene regulatory network. Physical Review Letters. 94: 128701. PMID 15903968 DOI: 10.1103/Physrevlett.94.128701  0.56
2005 Short SM, Derrien A, Narsimhan RP, Lawler J, Ingber DE, Zetter BR. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. The Journal of Cell Biology. 168: 643-53. PMID 15716381 DOI: 10.1083/Jcb.200407060  0.318
2005 Moore KA, Polte T, Huang S, Shi B, Alsberg E, Sunday ME, Ingber DE. Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 268-81. PMID 15614768 DOI: 10.1002/Dvdy.20237  0.59
2005 Heisterkamp A, Maxwell IZ, Kumar S, Underwood JM, Nickerson JA, Ingber DE, Mazur E. Nanosurgery in live cells using ultrashort laser pulses Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5695: 230-235. DOI: 10.1117/12.590467  0.321
2004 Overby DR, Alenghat FJ, Montoya-Zavala M, Bei H, Oh P, Karavitis J, Ingber DE. Magnetic Cellular Switches. Ieee Transactions On Magnetics. 40: 2958-2960. PMID 23097592 DOI: 10.1109/Tmag.2004.828991  0.703
2004 Alenghat FJ, Nauli SM, Kolb R, Zhou J, Ingber DE. Global cytoskeletal control of mechanotransduction in kidney epithelial cells. Experimental Cell Research. 301: 23-30. PMID 15501441 DOI: 10.1016/J.Yexcr.2004.08.003  0.705
2004 Saxena V, Hwang CW, Huang S, Eichbaum Q, Ingber D, Orgill DP. Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plastic and Reconstructive Surgery. 114: 1086-96; discussion . PMID 15457017 DOI: 10.1097/01.Prs.0000135330.51408.97  0.566
2004 Sultan C, Stamenović D, Ingber DE. A computational tensegrity model predicts dynamic rheological behaviors in living cells. Annals of Biomedical Engineering. 32: 520-30. PMID 15117025 DOI: 10.1023/B:Abme.0000019171.26711.37  0.38
2004 Mammoto A, Huang S, Moore K, Oh P, Ingber DE. Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. The Journal of Biological Chemistry. 279: 26323-30. PMID 15096506 DOI: 10.1074/Jbc.M402725200  0.617
2004 Polte TR, Eichler GS, Wang N, Ingber DE. Extracellular matrix controls myosin light chain phosphorylation and cell contractility through modulation of cell shape and cytoskeletal prestress. American Journal of Physiology. Cell Physiology. 286: C518-28. PMID 14761883 DOI: 10.1152/Ajpcell.00280.2003  0.421
2004 Matthews BD, Overby DR, Alenghat FJ, Karavitis J, Numaguchi Y, Allen PG, Ingber DE. Mechanical properties of individual focal adhesions probed with a magnetic microneedle. Biochemical and Biophysical Research Communications. 313: 758-64. PMID 14697256 DOI: 10.1016/J.Bbrc.2003.12.005  0.701
2003 Ingber DE. Mechanobiology and diseases of mechanotransduction. Annals of Medicine. 35: 564-77. PMID 14708967 DOI: 10.1080/07853890310016333  0.342
2003 Brock A, Chang E, Ho CC, LeDuc P, Jiang X, Whitesides GM, Ingber DE. Geometric determinants of directional cell motility revealed using microcontact printing. Langmuir : the Acs Journal of Surfaces and Colloids. 19: 1611-7. PMID 14674434 DOI: 10.1021/La026394K  0.803
2003 Eichler GS, Huang S, Ingber DE. Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles. Bioinformatics (Oxford, England). 19: 2321-2. PMID 14630665 DOI: 10.1093/Bioinformatics/Btg307  0.509
2003 Numaguchi Y, Huang S, Polte TR, Eichler GS, Wang N, Ingber DE. Caldesmon-dependent switching between capillary endothelial cell growth and apoptosis through modulation of cell shape and contractility. Angiogenesis. 6: 55-64. PMID 14517405 DOI: 10.1023/A:1025821517679  0.619
2003 Chen CS, Alonso JL, Ostuni E, Whitesides GM, Ingber DE. Cell shape provides global control of focal adhesion assembly. Biochemical and Biophysical Research Communications. 307: 355-61. PMID 12859964 DOI: 10.1016/S0006-291X(03)01165-3  0.674
2003 Brock A, Huang S, Ingber DE. Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology. Bmc Cell Biology. 4: 6. PMID 12848903 DOI: 10.1186/1471-2121-4-6  0.714
2003 Hu S, Chen J, Fabry B, Numaguchi Y, Gouldstone A, Ingber DE, Fredberg JJ, Butler JP, Wang N. Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. American Journal of Physiology. Cell Physiology. 285: C1082-90. PMID 12839836 DOI: 10.1152/Ajpcell.00159.2003  0.338
2003 Ingber DE. Tensegrity II. How structural networks influence cellular information processing networks. Journal of Cell Science. 116: 1397-408. PMID 12640025 DOI: 10.1242/Jcs.00360  0.408
2003 Takayama S, Ostuni E, LeDuc P, Naruse K, Ingber DE, Whitesides GM. Selective chemical treatment of cellular microdomains using multiple laminar streams. Chemistry & Biology. 10: 123-30. PMID 12618184 DOI: 10.1016/S1074-5521(03)00019-X  0.728
2003 Ingber DE. Tensegrity I. Cell structure and hierarchical systems biology. Journal of Cell Science. 116: 1157-73. PMID 12615960 DOI: 10.1242/Jcs.00359  0.388
2003 Ingber DE. Mechanosensation through integrins: cells act locally but think globally. Proceedings of the National Academy of Sciences of the United States of America. 100: 1472-4. PMID 12578965 DOI: 10.1073/Pnas.0530201100  0.442
2003 Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nature Genetics. 33: 129-37. PMID 12514735 DOI: 10.1038/Ng1076  0.699
2003 Numaguchi Y, Huang S, Ingber DE. Caldesmon regulates apoptosis and cell cycle progression in capillary endothelial cells and inhibits angiogenesis in vitro Journal of the American College of Cardiology. 41: 297. DOI: 10.1016/S0735-1097(03)82391-4  0.587
2002 Stamenović D, Ingber DE. Models of cytoskeletal mechanics of adherent cells. Biomechanics and Modeling in Mechanobiology. 1: 95-108. PMID 14586710 DOI: 10.1007/S10237-002-0009-9  0.372
2002 Ingber DE. Cancer as a disease of epithelial-mesenchymal interactions and extracellular matrix regulation. Differentiation; Research in Biological Diversity. 70: 547-60. PMID 12492496 DOI: 10.1046/J.1432-0436.2002.700908.X  0.344
2002 Ingber DE. Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circulation Research. 91: 877-87. PMID 12433832 DOI: 10.1161/01.Res.0000039537.73816.E5  0.413
2002 Parker KK, Brock AL, Brangwynne C, Mannix RJ, Wang N, Ostuni E, Geisse NA, Adams JC, Whitesides GM, Ingber DE. Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1195-204. PMID 12153987 DOI: 10.1096/Fj.02-0038Com  0.774
2002 Castedo M, Roumier T, Blanco J, Ferri KF, Barretina J, Tintignac LA, Andreau K, Perfettini JL, Amendola A, Nardacci R, Leduc P, Ingber DE, Druillennec S, Roques B, Leibovitch SA, et al. Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. The Embo Journal. 21: 4070-80. PMID 12145207 DOI: 10.1093/Emboj/Cdf391  0.639
2002 Wang N, Ostuni E, Whitesides GM, Ingber DE. Micropatterning tractional forces in living cells. Cell Motility and the Cytoskeleton. 52: 97-106. PMID 12112152 DOI: 10.1002/Cm.10037  0.524
2002 LeDuc P, Ostuni E, Whitesides G, Ingber D. Use of micropatterned adhesive surfaces for control of cell behavior. Methods in Cell Biology. 69: 385-401. PMID 12071006 DOI: 10.1016/S0091-679X(02)69024-7  0.716
2002 Moore KA, Huang S, Kong Y, Sunday ME, Ingber DE. Control of embryonic lung branching morphogenesis by the Rho activator, cytotoxic necrotizing factor 1. The Journal of Surgical Research. 104: 95-100. PMID 12020126 DOI: 10.1006/Jsre.2002.6418  0.568
2002 Huang S, Ingber DE. A discrete cell cycle checkpoint in late G(1) that is cytoskeleton-dependent and MAP kinase (Erk)-independent. Experimental Cell Research. 275: 255-64. PMID 11969294 DOI: 10.1006/Excr.2002.5504  0.555
2002 Alenghat FJ, Ingber DE. Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins. Science's Stke : Signal Transduction Knowledge Environment. 2002: pe6. PMID 11842240 DOI: 10.1126/Stke.2002.119.Pe6  0.729
2002 Goldmann WH, Ingber DE. Intact vinculin protein is required for control of cell shape, cell mechanics, and rac-dependent lamellipodia formation. Biochemical and Biophysical Research Communications. 290: 749-55. PMID 11785963 DOI: 10.1006/Bbrc.2001.6243  0.421
2002 Jiang X, Takayama S, Qian X, Ostuni E, Wu H, Bowden N, LeDuc P, Ingber DE, Whitesides GM. Controlling mammalian cell spreading and cytoskeletal arrangement with conveniently fabricated continuous wavy features on poly(dimethylsiloxane) Langmuir. 18: 3273-3280. DOI: 10.1021/La011668+  0.717
2001 Flusberg DA, Numaguchi Y, Ingber DE. Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. Molecular Biology of the Cell. 12: 3087-94. PMID 11598193 DOI: 10.1091/Mbc.12.10.3087  0.41
2001 Whitesides GM, Ostuni E, Takayama S, Jiang X, Ingber DE. Soft lithography in biology and biochemistry. Annual Review of Biomedical Engineering. 3: 335-73. PMID 11447067 DOI: 10.1146/Annurev.Bioeng.3.1.335  0.423
2001 Wang N, Naruse K, Stamenović D, Fredberg JJ, Mijailovich SM, Tolić-Nørrelykke IM, Polte T, Mannix R, Ingber DE. Mechanical behavior in living cells consistent with the tensegrity model. Proceedings of the National Academy of Sciences of the United States of America. 98: 7765-70. PMID 11438729 DOI: 10.1073/Pnas.141199598  0.411
2001 Takayama S, Ostuni E, LeDuc P, Naruse K, Ingber DE, Whitesides GM. Subcellular positioning of small molecules. Nature. 411: 1016. PMID 11429594 DOI: 10.1038/35082637  0.697
2001 Ostuni E, Chen CS, Ingber DE, Whitesides GM. Selective Deposition of Proteins and Cells in Arrays of Microwells Langmuir. 17: 2828-2834. DOI: 10.1021/La001372O  0.647
2001 Takayama S, Ostuni E, Qian X, McDonald JC, Jiang X, LeDuc P, Wu MH, Ingber DE, Whitesides GM. Topographical micropatterning of poly(dimethylsiloxane) using laminar flows of liquids in capillaries Advanced Materials. 13: 570-574. DOI: 10.1002/1521-4095(200104)13:8<570::Aid-Adma570>3.0.Co;2-B  0.656
2000 Brangwynne C, Huang S, Parker KK, Ingber DE, Ostuni E. Symmetry breaking in cultured mammalian cells. In Vitro Cellular & Developmental Biology. Animal. 36: 563-5. PMID 11212140 DOI: 10.1007/Bf02577523  0.676
2000 Ingber DE. The origin of cellular life. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 1160-70. PMID 11084632 DOI: 10.1002/1521-1878(200012)22:12<1160::Aid-Bies14>3.0.Co;2-5  0.34
2000 Huang S, Ingber DE. Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks. Experimental Cell Research. 261: 91-103. PMID 11082279 DOI: 10.1006/Excr.2000.5044  0.626
2000 Alenghat FJ, Fabry B, Tsai KY, Goldmann WH, Ingber DE. Analysis of cell mechanics in single vinculin-deficient cells using a magnetic tweezer. Biochemical and Biophysical Research Communications. 277: 93-9. PMID 11027646 DOI: 10.1006/Bbrc.2000.3636  0.729
2000 Ingber DE. Opposing views on tensegrity as a structural framework for understanding cell mechanics. Journal of Applied Physiology (Bethesda, Md. : 1985). 89: 1663-70. PMID 11007610 DOI: 10.1152/Jappl.2000.89.4.1663  0.322
2000 Meyer CJ, Alenghat FJ, Rim P, Fong JH, Fabry B, Ingber DE. Mechanical control of cyclic AMP signalling and gene transcription through integrins. Nature Cell Biology. 2: 666-8. PMID 10980709 DOI: 10.1038/35023621  0.704
2000 Chen CS, Ostuni E, Whitesides GM, Ingber DE. Using self-assembled monolayers to pattern ECM proteins and cells on substrates. Methods in Molecular Biology (Clifton, N.J.). 139: 209-19. PMID 10840789 DOI: 10.1385/1-59259-063-2:209  0.564
2000 Chiu DT, Jeon NL, Huang S, Kane RS, Wargo CJ, Choi IS, Ingber DE, Whitesides GM. Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proceedings of the National Academy of Sciences of the United States of America. 97: 2408-13. PMID 10681460 DOI: 10.1073/Pnas.040562297  0.625
1999 Kane RS, Takayama S, Ostuni E, Ingber DE, Whitesides GM. Patterning proteins and cells using soft lithography. Biomaterials. 20: 2363-76. PMID 10614942 DOI: 10.1016/S0142-9612(99)00165-9  0.433
1999 Zhao H, Bojanowski K, Ingber DE, Panigrahy D, Pepper MS, Montesano R, Shing Y. New role for tRNA and its fragment purified from human urinary bladder carcinoma conditioned medium: inhibition of endothelial cell growth. Journal of Cellular Biochemistry. 76: 109-17. PMID 10581005 DOI: 10.1002/(Sici)1097-4644(20000101)76:1<109::Aid-Jcb11>3.0.Co;2-K  0.377
1999 Huang S, Ingber DE. The structural and mechanical complexity of cell-growth control. Nature Cell Biology. 1: E131-8. PMID 10559956 DOI: 10.1038/13043  0.625
1999 Dike LE, Chen CS, Mrksich M, Tien J, Whitesides GM, Ingber DE. Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates. In Vitro Cellular & Developmental Biology. Animal. 35: 441-8. PMID 10501083 DOI: 10.1007/S11626-999-0050-4  0.784
1999 Gechtman Z, Alonso JL, Raab G, Ingber DE, Klagsbrun M. The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading. The Journal of Biological Chemistry. 274: 28828-35. PMID 10497257 DOI: 10.1074/Jbc.274.40.28828  0.319
1999 Chen CS, Brangwynne C, Ingber DE. Pictures in cell biology: squaring up to the cell-shape debate. Trends in Cell Biology. 9: 283. PMID 10438233 DOI: 10.1016/S0962-8924(99)01551-2  0.627
1999 Chen CS, Ingber DE. Tensegrity and mechanoregulation: from skeleton to cytoskeleton. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 7: 81-94. PMID 10367017 DOI: 10.1053/Joca.1998.0164  0.599
1999 Ingber D. How cells (might) sense microgravity. The Faseb Journal. 13: 3-15. PMID 10352140 DOI: 10.1096/Fasebj.13.9001.S3  0.402
1998 Huang S, Chen CS, Ingber DE. Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. Molecular Biology of the Cell. 9: 3179-93. PMID 9802905 DOI: 10.1091/Mbc.9.11.3179  0.729
1998 Ingber DE. Cellular basis of mechanotransduction. The Biological Bulletin. 194: 323-5; discussion 32. PMID 9664657 DOI: 10.2307/1543102  0.38
1998 Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Micropatterned surfaces for control of cell shape, position, and function. Biotechnology Progress. 14: 356-63. PMID 9622515 DOI: 10.1021/Bp980031M  0.755
1998 Pourati J, Maniotis A, Spiegel D, Schaffer JL, Butler JP, Fredberg JJ, Ingber DE, Stamenovic D, Wang N. Is cytoskeletal tension a major determinant of cell deformability in adherent endothelial cells? The American Journal of Physiology. 274: C1283-9. PMID 9612215 DOI: 10.1152/Ajpcell.1998.274.5.C1283  0.412
1998 Chicurel ME, Singer RH, Meyer CJ, Ingber DE. Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions. Nature. 392: 730-3. PMID 9565036 DOI: 10.1038/33719  0.366
1998 Chicurel ME, Chen CS, Ingber DE. Cellular control lies in the balance of forces. Current Opinion in Cell Biology. 10: 232-9. PMID 9561847 DOI: 10.1016/S0955-0674(98)80145-2  0.592
1998 Lee KM, Tsai KY, Wang N, Ingber DE. Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility. The American Journal of Physiology. 274: H76-82. PMID 9458854 DOI: 10.1152/Ajpheart.1998.274.1.H76  0.375
1998 Roberts C, Chen CS, Mrksich M, Martichonok V, Ingber DE, Whitesides GM. Using mixed self-assembled monolayers presenting RGD and (EG)3OH groups to characterize long-term attachment of bovine capillary endothelial cells to surfaces Journal of the American Chemical Society. 120: 6548-6555. DOI: 10.1021/Ja972467O  0.627
1997 Mrksich M, Dike LE, Tien J, Ingber DE, Whitesides GM. Using microcontact printing to pattern the attachment of mammalian cells to self-assembled monolayers of alkanethiolates on transparent films of gold and silver. Experimental Cell Research. 235: 305-13. PMID 9299154 DOI: 10.1006/Excr.1997.3668  0.682
1997 Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Geometric control of cell life and death. Science (New York, N.Y.). 276: 1425-8. PMID 9162012 DOI: 10.1126/Science.276.5317.1425  0.75
1997 Ingber DE. Tensegrity: the architectural basis of cellular mechanotransduction. Annual Review of Physiology. 59: 575-99. PMID 9074778 DOI: 10.1146/Annurev.Physiol.59.1.575  0.41
1997 Ezzell RM, Goldmann WH, Wang N, Parashurama N, Parasharama N, Ingber DE. Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton. Experimental Cell Research. 231: 14-26. PMID 9056408 DOI: 10.1006/Excr.1996.3451  0.401
1997 Maniotis AJ, Chen CS, Ingber DE. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proceedings of the National Academy of Sciences of the United States of America. 94: 849-54. PMID 9023345 DOI: 10.1073/Pnas.94.3.849  0.587
1996 Stamenović D, Fredberg JJ, Wang N, Butler JP, Ingber DE. A microstructural approach to cytoskeletal mechanics based on tensegrity. Journal of Theoretical Biology. 181: 125-36. PMID 8935591 DOI: 10.1006/Jtbi.1996.0120  0.344
1996 Mrksich M, Chen CS, Xia Y, Dike LE, Ingber DE, Whitesides GM. Controlling cell attachment on contoured surfaces with self-assembled monolayers of alkanethiolates on gold. Proceedings of the National Academy of Sciences of the United States of America. 93: 10775-8. PMID 8855256 DOI: 10.1073/Pnas.93.20.10775  0.609
1996 Fong JH, Ingber DE. Modulation of adhesion-dependent cAMP signaling by echistatin and alendronate. Biochemical and Biophysical Research Communications. 221: 19-24. PMID 8660334 DOI: 10.1006/Bbrc.1996.0537  0.341
1996 McNamee HP, Liley HG, Ingber DE. Integrin-dependent control of inositol lipid synthesis in vascular endothelial cells and smooth muscle cells. Experimental Cell Research. 224: 116-22. PMID 8612675 DOI: 10.1006/Excr.1996.0118  0.396
1996 Yoshida M, Westlin WF, Wang N, Ingber DE, Rosenzweig A, Resnick N, Gimbrone MA. Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. The Journal of Cell Biology. 133: 445-55. PMID 8609175 DOI: 10.1083/Jcb.133.2.445  0.326
1995 Wang N, Ingber DE. Probing transmembrane mechanical coupling and cytomechanics using magnetic twisting cytometry. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 327-35. PMID 8703406 DOI: 10.1139/O95-041  0.378
1995 Ingber DE, Prusty D, Sun Z, Betensky H, Wang N. Cell shape, cytoskeletal mechanics, and cell cycle control in angiogenesis. Journal of Biomechanics. 28: 1471-84. PMID 8666587 DOI: 10.1016/0021-9290(95)00095-X  0.427
1995 Plopper GE, McNamee HP, Dike LE, Bojanowski K, Ingber DE. Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. Molecular Biology of the Cell. 6: 1349-65. PMID 8573791 DOI: 10.1091/Mbc.6.10.1349  0.332
1994 Kusaka M, Sudo K, Matsutani E, Kozai Y, Marui S, Fujita T, Ingber D, Folkman J. Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470). British Journal of Cancer. 69: 212-216. PMID 8297716 DOI: 10.1038/Bjc.1994.41  0.335
1994 Singhvi R, Kumar A, Lopez GP, Stephanopoulos GN, Wang DI, Whitesides GM, Ingber DE. Engineering cell shape and function. Science (New York, N.Y.). 264: 696-8. PMID 8171320 DOI: 10.1126/Science.8171320  0.516
1994 Ingber DE, Dike L, Hansen L, Karp S, Liley H, Maniotis A, McNamee H, Mooney D, Plopper G, Sims J. Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. International Review of Cytology. 150: 173-224. PMID 8169080 DOI: 10.1016/S0074-7696(08)61542-9  0.428
1994 Wong JY, Langer R, Ingber DE. Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 3201-4. PMID 8159724 DOI: 10.1073/Pnas.91.8.3201  0.461
1994 Wang N, Ingber DE. Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension. Biophysical Journal. 66: 2181-9. PMID 8075352 DOI: 10.1016/S0006-3495(94)81014-8  0.396
1994 Schwartz MA, Ingber DE. Integrating with integrins. Molecular Biology of the Cell. 5: 389-93. PMID 8054683 DOI: 10.1091/Mbc.5.4.389  0.322
1994 Hansen LK, Mooney DJ, Vacanti JP, Ingber DE. Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth. Molecular Biology of the Cell. 5: 967-75. PMID 7841524 DOI: 10.1091/Mbc.5.9.967  0.381
1994 Mooney DJ, Hansen LK, Langer R, Vacanti JP, Ingber DE. Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover. Molecular Biology of the Cell. 5: 1281-8. PMID 7696710 DOI: 10.1091/Mbc.5.12.1281  0.5
1993 Mikos AG, Sarakinos G, Lyman MD, Ingber DE, Vacanti JP, Langer R. Prevascularization of porous biodegradable polymers. Biotechnology and Bioengineering. 42: 716-23. PMID 18613104 DOI: 10.1002/Bit.260420606  0.415
1993 McNamee HP, Ingber DE, Schwartz MA. Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown. The Journal of Cell Biology. 121: 673-8. PMID 8387531 DOI: 10.1083/Jcb.121.3.673  0.375
1993 Mikos AG, Bao Y, Cima LG, Ingber DE, Vacanti JP, Langer R. Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation. Journal of Biomedical Materials Research. 27: 183-9. PMID 8382203 DOI: 10.1002/Jbm.820270207  0.403
1993 Plopper G, Ingber DE. Rapid induction and isolation of focal adhesion complexes. Biochemical and Biophysical Research Communications. 193: 571-8. PMID 7685596 DOI: 10.1006/Bbrc.1993.1662  0.308
1993 Wang N, Butler JP, Ingber DE. Mechanotransduction across the cell surface and through the cytoskeleton. Science (New York, N.Y.). 260: 1124-7. PMID 7684161 DOI: 10.1126/Science.7684161  0.352
1993 Mooney D, Hansen L, Vacanti J, Langer R, Farmer S, Ingber D. Switching from differentiation to growth in hepatocytes: control by extracellular matrix. Journal of Cellular Physiology. 151: 497-505. PMID 1295898 DOI: 10.1002/Jcp.1041510308  0.507
1993 Wong JY, Langer R, Ingber DE. Cell Interactions With Fibronectin-Coated Electrically Conducting Polypyrrole Thin Films Mrs Proceedings. 331. DOI: 10.1557/Proc-331-141  0.402
1992 Wong JY, Langer RS, Ingber DE. Cell Attachment and Protein Adsorption to Polypyrrole thin Films Mrs Proceedings. 293. DOI: 10.1557/Proc-293-179  0.362
1991 Cima LG, Ingber DE, Vacanti JP, Langer R. Hepatocyte culture on biodegradable polymeric substrates. Biotechnology and Bioengineering. 38: 145-58. PMID 18600745 DOI: 10.1002/Bit.260380207  0.463
1991 Ingber D. Integrins as mechanochemical transducers. Current Opinion in Cell Biology. 3: 841-848. PMID 1931084 DOI: 10.1016/0955-0674(91)90058-7  0.399
1991 Ingber D. Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis. Journal of Cellular Biochemistry. 47: 236-241. PMID 1724246 DOI: 10.1002/Jcb.240470309  0.409
1991 Schwartz MA, Ingber DE, Lawrence M, Springer TA, Lechene C. Multiple integrins share the ability to induce elevation of intracellular pH. Experimental Cell Research. 195: 533-5. PMID 1712734 DOI: 10.1016/0014-4827(91)90407-L  0.343
1991 Schwartz MA, Lechene C, Ingber DE. Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. Proceedings of the National Academy of Sciences of the United States of America. 88: 7849-53. PMID 1652767 DOI: 10.1073/Pnas.88.17.7849  0.339
1991 Cima LG, Vacanti JP, Vacanti C, Ingber D, Mooney D, Langer R. Tissue engineering by cell transplantation using degradable polymer substrates. Journal of Biomechanical Engineering. 113: 143-51. PMID 1652042 DOI: 10.1115/1.2891228  0.447
1991 Mooney DJ, Cima L, Langer R, Johnson L, Hansen LK, Ingber DE, Vacant JP. Principles of Tissue Engineering and Reconstruction Using Polymer-Cell Constructs Mrs Proceedings. 252. DOI: 10.1557/Proc-252-345  0.404
1991 Mooney DJ, Langer R, Hansen LK, Vacanti JP, Ingber DE. Induction of Hepatocyte Differentiation by the Extracellular Matrix and an RGD-Containing Synthetic Peptide Mrs Proceedings. 252. DOI: 10.1557/Proc-252-199  0.436
1991 Johnson L, Aiken J, Mooney D, Schloo B, Cima L, Langer R, Ingber D, Vacanti J. The mesentery as a laminated vascular bed for hepatocyte transplantation on polymeric matrices Journal of Pediatric Surgery. 26: 500-501. DOI: 10.1016/0022-3468(91)91005-J  0.354
1990 Ingber DE. Fibronectin controls capillary endothelial cell growth by modulating cell shape. Proceedings of the National Academy of Sciences of the United States of America. 87: 3579-83. PMID 2333303 DOI: 10.1073/Pnas.87.9.3579  0.427
1990 Ingber DE, Prusty D, Frangioni JV, Cragoe EJ, Lechene C, Schwartz MA. Control of intracellular pH and growth by fibronectin in capillary endothelial cells. The Journal of Cell Biology. 110: 1803-11. PMID 2159481 DOI: 10.1083/Jcb.110.5.1803  0.348
1989 Whalen GF, Ingber DE. Inhibition of tumor-cell attachment to extracellular matrix as a method for preventing tumor recurrence in a surgical wound. Annals of Surgery. 210: 758-64. PMID 2686568 DOI: 10.1097/00000658-198912000-00011  0.321
1989 Ingber DE, Folkman J. Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix. The Journal of Cell Biology. 109: 317-30. PMID 2473081 DOI: 10.1083/Jcb.109.1.317  0.408
1989 Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia Nature. 339: 58-61. PMID 2469964 DOI: 10.1038/339058A0  0.311
1987 Ingber DE, Madri JA, Folkman J. Endothelial growth factors and extracellular matrix regulate DNA synthesis through modulation of cell and nuclear expansion. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 23: 387-94. PMID 2438264 DOI: 10.1007/Bf02620997  0.389
1986 Ingber DE, Madri JA, Jamieson JD. Basement membrane as a spatial organizer of polarized epithelia. Exogenous basement membrane reorients pancreatic epithelial tumor cells in vitro. The American Journal of Pathology. 122: 129-39. PMID 3942197  0.589
1986 Ingber DE, Madri JA, Folkman J. A possible mechanism for inhibition of angiogenesis by angiostatic steroids: induction of capillary basement membrane dissolution. Endocrinology. 119: 1768-75. PMID 2428602 DOI: 10.1210/Endo-119-4-1768  0.311
1985 Ingber DE, Madri JA, Jamieson JD. Neoplastic disorganization of pancreatic epithelial cell-cell relations. Role of basement membrane. The American Journal of Pathology. 121: 248-60. PMID 4061565  0.569
1981 Jamieson JD, Ingber DE, Muresan V, Hull BE, Sarras MP, Maylié-Pfenninger MF, Iwanij V. Cell surface properties of normal, differentiating, and neoplastic pancreatic acinar cells. Cancer. 47: 1516-27. PMID 7023646 DOI: 10.1002/1097-0142(19810315)47:6+<1516::Aid-Cncr2820471413>3.0.Co;2-9  0.628
1981 Ingber DE, Madri JA, Jamieson JD. Role of basal lamina in neoplastic disorganization of tissue architecture. Proceedings of the National Academy of Sciences of the United States of America. 78: 3901-5. PMID 7022458 DOI: 10.1073/Pnas.78.6.3901  0.609
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