Natalie Strynadka - Related publications

Affiliations: 
Biochemistry and Molecular Biology University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
structure-based design of novel, therapeutically useful antibiotics and inhibitors of antibiotic-resistance mechanisms
Website:
http://www.biochem.ubc.ca/faculty/natalie-strynadka/
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Gerrard Wheeler MC, Arias CL, E Mello JDFR, Cirauqui Diaz N, Rodrigues CR, Drincovich MF, de Souza AMT, Alvarez CE. Structural insights into the allosteric site of Arabidopsis NADP-malic enzyme 2: role of the second sphere residues in the regulatory signal transmission. Plant Molecular Biology. PMID 34333694 DOI: 10.1007/s11103-021-01176-2   
2021 Sugiura S, Nakano S, Niwa M, Hasebe F, Matsui D, Ito S. Catalytic Mechanism of Ancestral L-Lysine Oxidase Assigned by Sequence Data Mining. The Journal of Biological Chemistry. 101043. PMID 34358565 DOI: 10.1016/j.jbc.2021.101043   
2021 Marshall AC, Bruning JB. Engineering potassium activation into biosynthetic thiolase. The Biochemical Journal. PMID 34338286 DOI: 10.1042/BCJ20210455   
2021 Wangpaiboon K, Laohawuttichai P, Kim SY, Mori T, Nakapong S, Pichyangkura R, Pongsawasdi P, Hakoshima T, Krusong K. A GH13 α-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides. Acta Crystallographica. Section D, Structural Biology. 77: 1064-1076. PMID 34342279 DOI: 10.1107/S205979832100677X   
2021 Zhang X, Huang Z, Wang D, Zhang Y, Eser BE, Gu Z, Dai R, Gao R, Guo Z. A new thermophilic extradiol dioxygenase promises biodegradation of catecholic pollutants. Journal of Hazardous Materials. 422: 126860. PMID 34399224 DOI: 10.1016/j.jhazmat.2021.126860   
2021 Pandey S, Mahanta P, Berger BW, Acharya R. Structural insights into the mechanism of pH-selective substrate specificity of the polysaccharide lyase Smlt1473. The Journal of Biological Chemistry. 101014. PMID 34358563 DOI: 10.1016/j.jbc.2021.101014   
2021 Bandyopadhyay A, Saxena AK. Structural and ATPase activity analysis of nucleotide binding domain of Rv3870 enzyme of M. tuberculosis ESX-1 system. International Journal of Biological Macromolecules. PMID 34428493 DOI: 10.1016/j.ijbiomac.2021.08.130   
2021 Martínez-Aldino IY, Villaseca-Murillo M, Morales-Jiménez J, Rivera-Chávez J. Absolute configuration and protein tyrosine phosphatase 1B inhibitory activity of xanthoepocin, a dimeric naphtopyrone from Penicillium sp. IQ-429. Bioorganic Chemistry. 115: 105166. PMID 34384957 DOI: 10.1016/j.bioorg.2021.105166   
2021 Bai Y, Parker EJ. Reciprocal allostery arising from a bi-enzyme assembly controls aromatic amino acid biosynthesis in Prevotella nigrescens. The Journal of Biological Chemistry. 101038. PMID 34343567 DOI: 10.1016/j.jbc.2021.101038   
2021 Sartor P, Denkhaus L, Gerhardt S, Einsle O, Fetzner S. Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis. Journal of Structural Biology. 107794. PMID 34506908 DOI: 10.1016/j.jsb.2021.107794   
2021 Morzywolek A, Plotka M, Kaczorowska AK, Szadkowska M, Kozlowski LP, Wyrzykowski D, Makowska J, Waters JJ, Swift SM, Donovan DM, Kaczorowski T. Novel Lytic Enzyme of Prophage Origin from E3 Strain Alaska E43 with Bactericidal Activity against Clostridial Cells. International Journal of Molecular Sciences. 22. PMID 34502443 DOI: 10.3390/ijms22179536   
2021 Padavattan S, Jos S, Gogoi H, Bagautdinov B. Crystal structure of enoyl-CoA hydratase from Thermus thermophilus HB8. Acta Crystallographica. Section F, Structural Biology Communications. 77: 148-155. PMID 33949975 DOI: 10.1107/S2053230X21004593   
2021 Kröß C, Engele P, Sprenger B, Fischer A, Lingg N, Baier M, Öhlknecht C, Lier B, Oostenbrink C, Cserjan-Puschmann M, Striedner G, Jungbauer A, Schneider R. PROFICS: A bacterial selection system for directed evolution of proteases. The Journal of Biological Chemistry. 101095. PMID 34418435 DOI: 10.1016/j.jbc.2021.101095   
2021 Bakunova AK, Nikolaeva AY, Rakitina TV, Isaikina TY, Khrenova MG, Boyko KM, Popov VO, Bezsudnova EY. The Uncommon Active Site of D-Amino Acid Transaminase from : Biochemical and Structural Insights into the New Enzyme. Molecules (Basel, Switzerland). 26. PMID 34443642 DOI: 10.3390/molecules26165053   
2021 Currie MJ, Manjunath L, Horne CR, Rendle PM, Subramanian R, Friemann R, Fairbanks AJ, Muscroft-Taylor AC, North RA, Dobson RCJ. N-Acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization. The Journal of Biological Chemistry. 101113. PMID 34437902 DOI: 10.1016/j.jbc.2021.101113   
2021 Blain JM, Grote DL, Watkins SM, Goshu GM, Muller C, Gorman JL, Ranieri G, Walter RL, Hofstetter H, Horn JR, Hagen TJ. Structural and biophysical characterization of the Burkholderia pseudomallei IspF inhibitor L-tryptophan hydroxamate. Bioorganic & Medicinal Chemistry Letters. 48: 128273. PMID 34298132 DOI: 10.1016/j.bmcl.2021.128273   
2021 Nguyen TM, Goto M, Noda S, Matsutani M, Hodoya Y, Kataoka N, Adachi O, Matsushita K, Yakushi T. The 5-ketofructose reductase of sp. strain CHM43 is a novel class in the shikimate dehydrogenase family. Journal of Bacteriology. JB0055820. PMID 34309403 DOI: 10.1128/JB.00558-20   
2021 Pal S, Goswami S, Das D. Cross β amyloid assemblies as complex catalytic machinery. Chemical Communications (Cambridge, England). PMID 34278403 DOI: 10.1039/d1cc02880d   
2021 Chua SMH, Wizrah MSI, Luo Z, Lim BYJ, Kappler U, Kobe B, Fraser JA. Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets. The Journal of Biological Chemistry. 101091. PMID 34416230 DOI: 10.1016/j.jbc.2021.101091   
2021 Darrouzet E, Rinaldi C, Zambelli B, Ciurli S, Cavazza C. Revisiting the CooJ family, a potential chaperone for nickel delivery to [NiFe]‑carbon monoxide dehydrogenase. Journal of Inorganic Biochemistry. 225: 111588. PMID 34530332 DOI: 10.1016/j.jinorgbio.2021.111588   
2021 James MO. Enzyme Kinetics of PAPS-Sulfotransferase. Methods in Molecular Biology (Clifton, N.J.). 2342: 285-300. PMID 34272699 DOI: 10.1007/978-1-0716-1554-6_11   
2021 James MO. Enzyme Kinetics of PAPS-Sulfotransferase. Methods in Molecular Biology (Clifton, N.J.). 2342: 285-300. PMID 34272699 DOI: 10.1007/978-1-0716-1554-6_11   
2021 Ding N, Zhao B, Ban X, Li C, Venkataram Prasad BV, Gu Z, Li Z. Carbohydrate-Binding Module and Linker Allow Cold Adaptation and Salt Tolerance of Maltopentaose-Forming Amylase From Marine Bacterium 2-40 . Frontiers in Microbiology. 12: 708480. PMID 34335544 DOI: 10.3389/fmicb.2021.708480   
2021 Simon-Baram H, Kleiner D, Shmulevich F, Zarivach R, Zalk R, Tang H, Ding F, Bershtein S. SAMase of Bacteriophage T3 Inactivates Escherichia coli's Methionine -Adenosyltransferase by Forming Heteropolymers. Mbio. e0124221. PMID 34340545 DOI: 10.1128/mBio.01242-21   
2021 Mondal S, Thakur A, Fontes CMGA, Goyal A. A trimodular family 16 glycoside hydrolase from the cellulosome of displays highly specific licheninase (EC 3.2.1.73) activity. Microbiology (Reading, England). 167. PMID 34297654 DOI: 10.1099/mic.0.001055   
2021 Gyebi GA, Elfiky AA, Ogunyemi OM, Ibrahim IM, Adegunloye AP, Adebayo JO, Olaiya CO, Ocheje JO, Fabusiwa MM. Structure-based virtual screening suggests inhibitors of 3-Chymotrypsin-Like Protease of SARS-CoV-2 from Vernonia amygdalina and Occinum gratissimum. Computers in Biology and Medicine. 136: 104671. PMID 34332348 DOI: 10.1016/j.compbiomed.2021.104671   
2021 Sherry D, Worth R, Sayed Y. Elasticity-Associated Functionality and Inhibition of the HIV Protease. Advances in Experimental Medicine and Biology. PMID 34351572 DOI: 10.1007/5584_2021_655   
2021 Weiss AKH, Wurzer R, Klapec P, Eder MP, Loeffler JR, von Grafenstein S, Monteleone S, Liedl KR, Jansen-Dürr P, Gstach H. Inhibitors of Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1). Molecules (Basel, Switzerland). 26. PMID 34443596 DOI: 10.3390/molecules26165009   
2021 Carivenc C, Maveyraud L, Blanger C, Ballereau S, Roy-Camille C, Nguyen MC, Génisson Y, Guilhot C, Chalut C, Pedelacq JD, Mourey L. Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Scientific Reports. 11: 18042. PMID 34508141 DOI: 10.1038/s41598-021-97197-4   
2021 Olatunji S, Bowen K, Huang CY, Weichert D, Singh W, Tikhonova IG, Scanlan EM, Olieric V, Caffrey M. Structural basis of the membrane intramolecular transacylase reaction responsible for lyso-form lipoprotein synthesis. Nature Communications. 12: 4254. PMID 34253723 DOI: 10.1038/s41467-021-24475-0   
2021 Jeter VL, Escalante-Semerena JC. Sirtuin-dependent reversible lysine acetylation controls the activity of acetyl-Coenzyme A synthetase in . Journal of Bacteriology. JB0033321. PMID 34309396 DOI: 10.1128/JB.00333-21   
2021 Kummer MJ, Lee YS, Yuan M, Alkotaini B, Zhao J, Blumenthal E, Minteer SD. Substrate Channeling by a Rationally Designed Fusion Protein in a Biocatalytic Cascade. Jacs Au. 1: 1187-1197. PMID 34467357 DOI: 10.1021/jacsau.1c00180   
2021 Gabrielli V, Muñoz-García JC, Pergolizzi G, de Andrade P, Khimyak Y, Field RA, Angulo J. Molecular recognition of natural and non-natural substrates by cellodextrin phosphorylase from Ruminiclostridium thermocellum investigated by NMR spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34436794 DOI: 10.1002/chem.202102039   
2021 Singh A, Fenwick RB, Dyson HJ, Wright PE. Role of Active Site Loop Dynamics in Mediating Ligand Release from Dihydrofolate Reductase. Biochemistry. PMID 34428034 DOI: 10.1021/acs.biochem.1c00461   
2021 Jia Q, Zeng H, Li H, Xiao N, Tang J, Gao S, Zhang J, Xie W. The C-terminal loop of guanosine deaminase is essential to catalysis. Chemical Communications (Cambridge, England). PMID 34477187 DOI: 10.1039/d1cc03042f   
2021 Hamdan SH, Maiangwa J, Ali MSM, Normi YM, Sabri S, Leow TC. Thermostable lipases and their dynamics of improved enzymatic properties. Applied Microbiology and Biotechnology. PMID 34487207 DOI: 10.1007/s00253-021-11520-7   
2021 Marshall SA, Payne KAP, Fisher K, Titchiner GR, Levy C, Hay S, Leys D. UbiD domain dynamics underpins aromatic decarboxylation. Nature Communications. 12: 5065. PMID 34417452 DOI: 10.1038/s41467-021-25278-z   
2021 Jiang D, Li Y, Wu W, Zhang H, Xu R, Xu H, Zhan R, Sun L. Identification and engineering on the non-conserved residues of metallo-β-lactamase-type thioesterase to improve the enzymatic activity. Biotechnology and Bioengineering. PMID 34427915 DOI: 10.1002/bit.27921   
2021 Guo J, Wang Y, Gao W, Wang X, Gao X, Man Z, Cai Z, Qing Q. Gene Cloning, Functional Expression, and Characterization of a Novel GH46 Chitosanase from Streptomyces avermitilis (SaCsn46A). Applied Biochemistry and Biotechnology. PMID 34542822 DOI: 10.1007/s12010-021-03687-6   
2021 Watson RA, Offenbacher AR, Barry BA. Detection of Catalytically Linked Conformational Changes in Wild-Type Class Ia Ribonucleotide Reductase Using Reaction-Induced FTIR Spectroscopy. The Journal of Physical Chemistry. B. PMID 34289692 DOI: 10.1021/acs.jpcb.1c03038   
2021 Mori T, Zhai R, Ushimaru R, Matsuda Y, Abe I. Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI. Nature Communications. 12: 4417. PMID 34285212 DOI: 10.1038/s41467-021-24685-6   
2021 Yu Q, Ni D, Kowal J, Manolaridis I, Jackson SM, Stahlberg H, Locher KP. Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nature Communications. 12: 4376. PMID 34282134 DOI: 10.1038/s41467-021-24651-2   
2021 Yu Q, Ni D, Kowal J, Manolaridis I, Jackson SM, Stahlberg H, Locher KP. Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nature Communications. 12: 4376. PMID 34282134 DOI: 10.1038/s41467-021-24651-2   
2021 Miranda-Rojas S, Blanco-Esperguez K, Tuñón I, Kästner J, Mendizábal F. Exploration of the Activation Mechanism of the Epigenetic Regulator MLL3: A QM/MM Study. Biomolecules. 11. PMID 34356675 DOI: 10.3390/biom11071051   
2021 Feehan R, Franklin MW, Slusky JSG. Machine learning differentiates enzymatic and non-enzymatic metals in proteins. Nature Communications. 12: 3712. PMID 34140507 DOI: 10.1038/s41467-021-24070-3   
2021 Feehan R, Franklin MW, Slusky JSG. Machine learning differentiates enzymatic and non-enzymatic metals in proteins. Nature Communications. 12: 3712. PMID 34140507 DOI: 10.1038/s41467-021-24070-3   
2021 Kim SH, Park S, Park E, Kim JH, Ghatge S, Hur HG, Rhee S. Structure and substrate specificity determinants of NfnB, a dinitroaniline herbicide-catabolizing nitroreductase from Sphingopyxis sp. strain HMH. The Journal of Biological Chemistry. 101143. PMID 34473996 DOI: 10.1016/j.jbc.2021.101143   
2021 Hernández-Ochoa B, Navarrete-Vázquez G, Aguayo-Ortiz R, Ortiz-Ramírez P, Morales-Luna L, Martínez-Rosas V, González-Valdez A, Gómez-Chávez F, Enríquez-Flores S, Wong-Baeza C, Baeza-Ramírez I, Pérez de la Cruz V, Gómez-Manzo S. Identification and In Silico Characterization of Novel Glucose-6-Phosphate Dehydrogenase Inhibitors. Molecules (Basel, Switzerland). 26. PMID 34443540 DOI: 10.3390/molecules26164955   
2021 Moses ME, Lund PM, Bohr SS, Iversen JF, Kæstel-Hansen J, Kallenbach AS, Iversen L, Christensen SM, Hatzakis NS. Single-Molecule Study of Lipase in a Detergency Application System Reveals Diffusion Pattern Remodeling by Surfactants and Calcium. Acs Applied Materials & Interfaces. 13: 33704-33712. PMID 34235926 DOI: 10.1021/acsami.1c08809   
2021 Reiberger R, Radilová K, Kráľ M, Zima V, Majer P, Brynda J, Dračínský M, Konvalinka J, Kožíšek M, Machara A. Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors. International Journal of Molecular Sciences. 22. PMID 34299354 DOI: 10.3390/ijms22147735