Timothy J. Mitchison - Publications

Affiliations: 
Systems Biology Harvard Medical School, Boston, MA, United States 
Area:
Microtubules, Actin, Mitosis, Cell cycle
Website:
http://www.hms.harvard.edu/dms/bbs/fac/Mitchison.php

310 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Van Itallie ES, Field CM, Mitchison TJ, Kirschner MW. Dorsal lip maturation and initial archenteron extension depend on Wnt11 family ligands. Developmental Biology. 493: 67-79. PMID 36334838 DOI: 10.1016/j.ydbio.2022.10.013  0.583
2022 Ng TL, Olson EJ, Yoo TY, Weiss HS, Koide Y, Koch PD, Rollins NJ, Mach P, Meisinger T, Bricken T, Chang TZ, Molloy C, Zürcher J, Chang RL, Mitchison TJ, et al. High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response. Msystems. e0146621. PMID 35319251 DOI: 10.1128/msystems.01466-21  0.771
2021 Yoo TY, Mitchison T. Quantification of nuclear transport inhibition by SARS-CoV-2 ORF6 using a broadly applicable live-cell dose-response pipeline. Biorxiv : the Preprint Server For Biology. PMID 34931191 DOI: 10.1101/2021.12.10.472151  0.786
2021 Mitchison TJ, Field CM. Self-Organization of Cellular Units. Annual Review of Cell and Developmental Biology. PMID 34186005 DOI: 10.1146/annurev-cellbio-120319-025356  0.63
2021 Yoo TY, Mitchison TJ. O-GlcNAc modification of nuclear pore complexes accelerates bidirectional transport. The Journal of Cell Biology. 220. PMID 33909044 DOI: 10.1083/jcb.202010141  0.774
2020 Pelletier JF, Field CM, Fuerthauer S, Sonnett M, Mitchison TJ. Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm. Elife. 9. PMID 33284105 DOI: 10.7554/eLife.60047  0.637
2020 Luthria G, Li R, Wang S, Prytyskach M, Kohler RH, Lauffenburger DA, Mitchison TJ, Weissleder R, Miller MA. In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells. Nature Communications. 11: 3521. PMID 32665556 DOI: 10.1038/S41467-020-17147-Y  0.375
2020 Geisterfer ZM, Zhu DY, Mitchison TJ, Oakey J, Gatlin JC. Microtubule Growth Rates Are Sensitive to Global and Local Changes in Microtubule Plus-End Density. Current Biology : Cb. PMID 32531285 DOI: 10.1016/J.Cub.2020.05.056  0.455
2020 Gasic I, Groendyke BJ, Nowak RP, Yuan JC, Kalabathula J, Fischer ES, Gray NS, Mitchison TJ. Tubulin Resists Degradation by Cereblon-Recruiting PROTACs. Cells. 9. PMID 32349222 DOI: 10.3390/Cells9051083  0.795
2019 Lin Z, Gasic I, Chandrasekaran V, Peters N, Shao S, Mitchison TJ, Hegde RS. TTC5 mediates autoregulation of tubulin via mRNA degradation. Science (New York, N.Y.). PMID 31727855 DOI: 10.1126/Science.Aaz4352  0.809
2019 Mitchison TJ, Field CM. Toward synthetic cells. Science (New York, N.Y.). 366: 569-570. PMID 31672880 DOI: 10.1126/Science.Aaz5635  0.636
2019 Field CM, Pelletier JF, Mitchison TJ. Disassembly of Actin and Keratin Networks by Aurora B Kinase at the Midplane of Cleaving Xenopus laevis Eggs. Current Biology : Cb. PMID 31178324 DOI: 10.1016/J.Cub.2019.05.016  0.673
2019 Florian S, Iwamoto Y, Coughlin M, Weissleder R, Mitchison TJ. A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31101720 DOI: 10.1073/Pnas.1702372116  0.357
2019 Gasic I, Boswell SA, Mitchison TJ. Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues. Plos Biology. 17: e3000225. PMID 30964857 DOI: 10.1371/Journal.Pbio.3000225  0.812
2019 Song Y, Subramanian K, Berberich MJ, Rodriguez S, Latorre IJ, Luria CM, Everley R, Albers MW, Mitchison TJ, Sorger PK. A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line. Scientific Data. 6: 190016. PMID 30778261 DOI: 10.1038/Sdata.2019.16  0.731
2019 Nguyen T, Mitchison TJ, Wühr M. Immunofluorescence of Microtubule Assemblies in Amphibian Oocytes and Early Embryos. Methods in Molecular Biology (Clifton, N.J.). 1920: 17-32. PMID 30737683 DOI: 10.1007/978-1-4939-9009-2_2  0.821
2018 Pineda JJ, Miller MA, Song Y, Kuhn H, Mikula H, Tallapragada N, Weissleder R, Mitchison TJ. Site occupancy calibration of taxane pharmacology in live cells and tissues. Proceedings of the National Academy of Sciences of the United States of America. PMID 30429313 DOI: 10.1073/Pnas.1800047115  0.735
2018 Gasic I, Mitchison TJ. Autoregulation and repair in microtubule homeostasis. Current Opinion in Cell Biology. 56: 80-87. PMID 30415186 DOI: 10.1016/J.Ceb.2018.10.003  0.826
2018 Özkan Küçük NE, Şanal E, Tan E, Mitchison T, Özlü N. Labeling Carboxyl Groups of Surface Exposed Proteins Provides an Orthogonal Approach for Cell Surface Isolation. Journal of Proteome Research. PMID 29651847 DOI: 10.1021/Acs.Jproteome.7B00825  0.322
2018 Field CM, Mitchison TJ. Assembly of Spindles and Asters in Xenopus Egg Extracts. Cold Spring Harbor Protocols. PMID 29437996 DOI: 10.1101/Pdb.Prot099796  0.696
2017 Mitchison TJ, Field CM. Spindle-to-Cortex Communication in Cleaving Frog Eggs. Cold Spring Harbor Symposia On Quantitative Biology. PMID 29196560 DOI: 10.1101/Sqb.2017.82.033654  0.666
2017 Nguyen PA, Field CM, Mitchison TJ. Prc1E and Kif4A control microtubule organization within and between large egg asters. Molecular Biology of the Cell. 29: 304-316. PMID 29187577 DOI: 10.1091/Mbc.E17-09-0540  0.703
2017 Mitchison TJ, Pineda J, Shi J, Florian S. Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug? Open Biology. 7. PMID 29142107 DOI: 10.1098/Rsob.170182  0.308
2017 Guild J, Ginzberg MB, Hueschen CL, Mitchison TJ, Dumont S. Increased lateral microtubule contact at the cell cortex is sufficient to drive mammalian spindle elongation. Molecular Biology of the Cell. PMID 28468979 DOI: 10.1091/Mbc.E17-03-0171  0.447
2017 Costigliola N, Ding L, Burckhardt CJ, Han SJ, Gutierrez E, Mota A, Groisman A, Mitchison TJ, Danuser G. Vimentin fibers orient traction stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 28465431 DOI: 10.1073/Pnas.1614610114  0.363
2017 Hanley ML, Yoo TY, Sonnett M, Needleman DJ, Mitchison TJ. Chromosomal passenger complex hydrodynamics suggests chaperoning of the inactive state by nucleoplasmin/nucleophosmin. Molecular Biology of the Cell. PMID 28404751 DOI: 10.1091/Mbc.E16-12-0860  0.813
2017 Shi J, Mitchison TJ. Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic. Endocrine-Related Cancer. PMID 28249963 DOI: 10.1530/Erc-17-0003  0.316
2017 Zhang L, Hou Y, Li Z, Ji X, Wang Z, Wang H, Tian X, Yu F, Yang Z, Pi L, Mitchison TJ, Lu Q, Zhang X. 27 T ultra-high static magnetic field changes orientation and morphology of mitotic spindles in human cells. Elife. 6. PMID 28244368 DOI: 10.7554/Elife.22911  0.335
2016 Ishihara K, Korolev KS, Mitchison TJ. Physical basis of large microtubule aster growth. Elife. 5. PMID 27892852 DOI: 10.7554/Elife.19145  0.411
2016 Wang Y, Begley M, Li Q, Huang HT, Lako A, Eck MJ, Gray NS, Mitchison TJ, Cantley LC, Zhao JJ. Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528663 DOI: 10.1073/Pnas.1606862113  0.368
2016 Boke E, Ruer M, Wühr M, Coughlin M, Lemaitre R, Gygi SP, Alberti S, Drechsel D, Hyman AA, Mitchison TJ. Amyloid-like Self-Assembly of a Cellular Compartment. Cell. 166: 637-650. PMID 27471966 DOI: 10.1016/J.Cell.2016.06.051  0.796
2016 Groen AC, Mitchison TJ. Purification and Fluorescent Labeling of Tubulin from Xenopus laevis Egg Extracts. Methods in Molecular Biology (Clifton, N.J.). 1413: 35-45. PMID 27193841 DOI: 10.1007/978-1-4939-3542-0_3  0.751
2016 Al-Obaidi N, Mitchison TJ, Crews CM, Mayer TU. Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells. Acs Chemical Biology. PMID 27121275 DOI: 10.1021/Acschembio.6B00203  0.652
2016 Field CM, Pelletier JF, Mitchison TJ. Xenopus extract approaches to studying microtubule organization and signaling in cytokinesis Methods in Cell Biology. DOI: 10.1016/Bs.Mcb.2016.04.014  0.694
2015 Son S, Kang JH, Oh S, Kirschner MW, Mitchison TJ, Manalis S. Resonant microchannel volume and mass measurements show that suspended cells swell during mitosis. The Journal of Cell Biology. 211: 757-63. PMID 26598613 DOI: 10.1083/Jcb.201505058  0.65
2015 Wühr M, Güttler T, Peshkin L, McAlister GC, Sonnett M, Ishihara K, Groen AC, Presler M, Erickson BK, Mitchison TJ, Kirschner MW, Gygi SP. The Nuclear Proteome of a Vertebrate. Current Biology : Cb. 25: 2663-71. PMID 26441354 DOI: 10.1016/J.Cub.2015.08.047  0.793
2015 Kuhn H, Sopko R, Coughlin M, Perrimon N, Mitchison T. The Atg1-Tor pathway regulates yolk catabolism in Drosophila embryos. Development (Cambridge, England). PMID 26395483 DOI: 10.1242/Jcs.183491  0.311
2015 Field CM, Groen AC, Nguyen PA, Mitchison TJ. Spindle to cortex communication in cleaving, polyspermic Xenopus eggs. Molecular Biology of the Cell. PMID 26310438 DOI: 10.1091/Mbc.E15-04-0233  0.823
2015 Li L, Yin Q, Kuss P, Maliga Z, Millán JL, Wu H, Mitchison TJ. Erratum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs. Nature Chemical Biology. 11: 741. PMID 26284675 DOI: 10.1038/Nchembio0915-741C  0.66
2015 Mitchison TJ, Ishihara K, Nguyen P, Wühr M. Size Scaling of Microtubule Assemblies in Early Xenopus Embryos. Cold Spring Harbor Perspectives in Biology. PMID 26261283 DOI: 10.1101/Cshperspect.A019182  0.811
2015 Nguyen PA, Field CM, Groen AC, Mitchison TJ, Loose M. Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins. Methods in Cell Biology. 128: 223-41. PMID 25997350 DOI: 10.1016/Bs.Mcb.2015.01.007  0.792
2015 Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R, Danuser G, Mitchison TJ. In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy. Nature Methods. 12: 577-85. PMID 25867850 DOI: 10.1038/Nmeth.3363  0.345
2015 Krukenberg KA, Kim S, Tan ES, Maliga Z, Mitchison TJ. Extracellular poly(ADP-ribose) is a pro-inflammatory signal for macrophages. Chemistry & Biology. 22: 446-52. PMID 25865309 DOI: 10.1016/J.Chembiol.2015.03.007  0.697
2015 Li L, Yin Q, Kuss P, Maliga Z, Millán JL, Wu H, Mitchison TJ. Corrigendum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs. Nature Chemical Biology. 11: 235. PMID 25689338 DOI: 10.1038/Nchembio0315-235D  0.655
2015 Özlü N, Qureshi MH, Toyoda Y, Renard BY, Mollaoglu G, Özkan NE, Bulbul S, Poser I, Timm W, Hyman AA, Mitchison TJ, Steen JA. Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis. The Embo Journal. 34: 251-65. PMID 25476450 DOI: 10.15252/Embj.201385162  0.552
2014 Ishihara K, Nguyen PA, Groen AC, Field CM, Mitchison TJ. Microtubule nucleation remote from centrosomes may explain how asters span large cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 17715-22. PMID 25468969 DOI: 10.1073/Pnas.1418796111  0.833
2014 Li L, Yin Q, Kuss P, Maliga Z, Millán JL, Wu H, Mitchison TJ. Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs. Nature Chemical Biology. 10: 1043-8. PMID 25344812 DOI: 10.1038/Nchembio.1661  0.688
2014 Nguyen PA, Groen AC, Loose M, Ishihara K, Wühr M, Field CM, Mitchison TJ. Spatial organization of cytokinesis signaling reconstituted in a cell-free system. Science (New York, N.Y.). 346: 244-7. PMID 25301629 DOI: 10.1126/Science.1256773  0.826
2014 Ishihara K, Nguyen PA, Wühr M, Groen AC, Field CM, Mitchison TJ. Organization of early frog embryos by chemical waves emanating from centrosomes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369. PMID 25047608 DOI: 10.1098/Rstb.2013.0454  0.801
2014 Mitchison TJ. The engine of microtubule dynamics comes into focus. Cell. 157: 1008-10. PMID 24855939 DOI: 10.1016/J.Cell.2014.05.001  0.391
2014 Groen AC, Ngyuen PA, Field CM, Ishihara K, Mitchison TJ. Glycogen-supplemented mitotic cytosol for analyzing Xenopus egg microtubule organization. Methods in Enzymology. 540: 417-33. PMID 24630120 DOI: 10.1016/B978-0-12-397924-7.00023-6  0.819
2014 Field CM, Nguyen PA, Ishihara K, Groen AC, Mitchison TJ. Xenopus egg cytoplasm with intact actin. Methods in Enzymology. 540: 399-415. PMID 24630119 DOI: 10.1016/B978-0-12-397924-7.00022-4  0.82
2014 Coughlin M, Groen AC, Mitchison TJ. Electron microscopy of microtubule cytoskeleton assembly in vitro. Methods in Molecular Biology (Clifton, N.J.). 1117: 259-71. PMID 24357367 DOI: 10.1007/978-1-62703-776-1_12  0.768
2014 Loose M, Mitchison TJ. The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patterns. Nature Cell Biology. 16: 38-46. PMID 24316672 DOI: 10.1038/Ncb2885  0.402
2014 Prentice-Mott H, Chang C, Mahadevan L, Mitchison T, Irimia D, Shah J. Barotaxis in a Confined Neutrophil Biophysical Journal. 106: 360a. DOI: 10.1016/J.Bpj.2013.11.2045  0.321
2013 Prentice-Mott HV, Chang CH, Mahadevan L, Mitchison TJ, Irimia D, Shah JV. Biased migration of confined neutrophil-like cells in asymmetric hydraulic environments. Proceedings of the National Academy of Sciences of the United States of America. 110: 21006-11. PMID 24324148 DOI: 10.1073/Pnas.1317441110  0.318
2013 Wang S, Romano FB, Field CM, Mitchison TJ, Rapoport TA. Multiple mechanisms determine ER network morphology during the cell cycle in Xenopus egg extracts. The Journal of Cell Biology. 203: 801-14. PMID 24297752 DOI: 10.1083/Jcb.201308001  0.649
2013 Tang Y, Xie T, Florian S, Moerke N, Shamu C, Benes C, Mitchison TJ. Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay. Journal of Biomolecular Screening. 18: 1062-71. PMID 23788527 DOI: 10.1177/1087057113493804  0.315
2013 Kim S, Li L, Maliga Z, Yin Q, Wu H, Mitchison TJ. Anticancer flavonoids are mouse-selective STING agonists. Acs Chemical Biology. 8: 1396-401. PMID 23683494 DOI: 10.1021/Cb400264N  0.679
2013 Choi PJ, Mitchison TJ. Imaging burst kinetics and spatial coordination during serial killing by single natural killer cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 6488-93. PMID 23576740 DOI: 10.1073/Pnas.1221312110  0.308
2013 Kueh HY, Niethammer P, Mitchison TJ. Maintenance of mitochondrial oxygen homeostasis by cosubstrate compensation. Biophysical Journal. 104: 1338-48. PMID 23528093 DOI: 10.1016/J.Bpj.2013.01.030  0.668
2013 Mitchison TJ, Nguyen P, Coughlin M, Groen AC. Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol. Molecular Biology of the Cell. 24: 1559-73. PMID 23515222 DOI: 10.1091/Mbc.E12-12-0850  0.762
2013 Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R. Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo. Nature Communications. 4: 1504. PMID 23422672 DOI: 10.1038/Ncomms2506  0.317
2013 Petry S, Groen AC, Ishihara K, Mitchison TJ, Vale RD. Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2. Cell. 152: 768-77. PMID 23415226 DOI: 10.1016/J.Cell.2012.12.044  0.779
2013 Mitchison TJ. Abstract SY28-01: Is mitosis the target of “anti-mitotic” cancer drugs. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy28-01  0.307
2013 Florian S, Chittajallu DR, Kohler RH, Orth JD, Sorger PK, Weissleder R, Danuser G, Mitchison TJ. Abstract A297: Microtubule targeting antimitotic drugs induce a lower mitotic arrest than clinically less effective antimitotic Eg5 inhibitors in mouse xenografts. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A297  0.337
2012 Vale RD, DeRisi J, Phillips R, Mullins RD, Waterman C, Mitchison TJ. Graduate education. Interdisciplinary graduate training in teaching labs. Science (New York, N.Y.). 338: 1542-3. PMID 23258877 DOI: 10.1126/Science.1216570  0.57
2012 Maiuri P, Terriac E, Paul-Gilloteaux P, Vignaud T, McNally K, Onuffer J, Thorn K, Nguyen PA, Georgoulia N, Soong D, Jayo A, Beil N, Beneke J, Lim JC, Sim CP, ... ... Mitchison TJ, et al. The first World Cell Race. Current Biology : Cb. 22: R673-5. PMID 22974990 DOI: 10.1016/J.Cub.2012.07.052  0.803
2012 Kim S, Peshkin L, Mitchison TJ. Vascular disrupting agent drug classes differ in effects on the cytoskeleton. Plos One. 7: e40177. PMID 22848372 DOI: 10.1371/Journal.Pone.0040177  0.35
2012 Zhang X, Wang W, Bedigian AV, Coughlin ML, Mitchison TJ, Eggert US. Dopamine receptor D3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI. Proceedings of the National Academy of Sciences of the United States of America. 109: 12485-90. PMID 22802617 DOI: 10.1073/Pnas.1207821109  0.679
2012 Mitchison T, Wühr M, Nguyen P, Ishihara K, Groen A, Field CM. Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells. Cytoskeleton (Hoboken, N.J.). 69: 738-50. PMID 22786885 DOI: 10.1002/Cm.21050  0.819
2012 Dumont S, Salmon ED, Mitchison TJ. Deformations within moving kinetochores reveal different sites of active and passive force generation. Science (New York, N.Y.). 337: 355-8. PMID 22722252 DOI: 10.1126/Science.1221886  0.339
2012 Nguyen PA, Ishihara K, Wühr M, Mitchison TJ. Pronuclear migration: no attachment? No union, but a futile cycle! Current Biology : Cb. 22: R409-11. PMID 22625860 DOI: 10.1016/J.Cub.2012.03.062  0.791
2012 Hu CK, Ozlü N, Coughlin M, Steen JJ, Mitchison TJ. Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis. Molecular Biology of the Cell. 23: 2702-11. PMID 22621898 DOI: 10.1091/Mbc.E12-01-0058  0.652
2012 Hu CK, Coughlin M, Mitchison TJ. Midbody assembly and its regulation during cytokinesis. Molecular Biology of the Cell. 23: 1024-34. PMID 22278743 DOI: 10.1091/Mbc.E11-08-0721  0.66
2012 Kwiatkowski N, Deng X, Wang J, Tan L, Villa F, Santaguida S, Huang HC, Mitchison T, Musacchio A, Gray N. Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen. Acs Chemical Biology. 7: 185-96. PMID 21992004 DOI: 10.1021/Cb200305U  0.575
2012 Georgoulia NE, Mitchison TJ. Abstract 35: Breast cancer cell interactions Cancer Research. 72: 35-35. DOI: 10.1158/1538-7445.Am2012-35  0.785
2012 Garner E, Wang W, Bernard R, Rudner D, Zhuang X, Mitchison T. Watching the Motions of the Cell Wall Synthesis Machinery and Underlying Cytoskeleton in B. Subtilis Biophysical Journal. 102: 697a. DOI: 10.1016/J.Bpj.2011.11.3782  0.747
2012 Zidovska A, Weitz DA, Mitchison TJ. Mechanism and Function of Chromatin Positional Dynamics Biophysical Journal. 102: 479a. DOI: 10.1016/J.Bpj.2011.11.2629  0.351
2011 Akhtar A, Fuchs E, Mitchison T, Shaw RJ, St Johnston D, Strasser A, Taylor S, Walczak C, Zerial M. A decade of molecular cell biology: achievements and challenges. Nature Reviews. Molecular Cell Biology. 12: 669-74. PMID 21941276 DOI: 10.1038/Nrm3187  0.612
2011 Tang Y, Orth JD, Xie T, Mitchison TJ. Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells. Cancer Letters. 310: 15-24. PMID 21782324 DOI: 10.1016/J.Canlet.2011.05.024  0.321
2011 Groen AC, Coughlin M, Mitchison TJ. Microtubule assembly in meiotic extract requires glycogen. Molecular Biology of the Cell. 22: 3139-51. PMID 21737678 DOI: 10.1091/Mbc.E11-02-0158  0.764
2011 Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ. Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer Research. 71: 4608-16. PMID 21712408 DOI: 10.1158/0008-5472.Can-11-0412  0.321
2011 Garner EC, Bernard R, Wang W, Zhuang X, Rudner DZ, Mitchison T. Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis. Science (New York, N.Y.). 333: 222-5. PMID 21636745 DOI: 10.1126/Science.1203285  0.737
2011 Field CM, Wühr M, Anderson GA, Kueh HY, Strickland D, Mitchison TJ. Actin behavior in bulk cytoplasm is cell cycle regulated in early vertebrate embryos. Journal of Cell Science. 124: 2086-95. PMID 21610091 DOI: 10.1242/Dev.070102  0.817
2011 Hu CK, Coughlin M, Field CM, Mitchison TJ. KIF4 regulates midzone length during cytokinesis. Current Biology : Cb. 21: 815-24. PMID 21565503 DOI: 10.1016/J.Cub.2011.04.019  0.78
2011 Wühr M, Obholzer ND, Megason SG, Detrich HW, Mitchison TJ. Live imaging of the cytoskeleton in early cleavage-stage zebrafish embryos. Methods in Cell Biology. 101: 1-18. PMID 21550437 DOI: 10.1016/B978-0-12-387036-0.00001-3  0.416
2011 Shi J, Zhou Y, Huang HC, Mitchison TJ. Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL. Cancer Research. 71: 4518-26. PMID 21546570 DOI: 10.1158/0008-5472.Can-10-4336  0.552
2011 Brangwynne CP, Mitchison TJ, Hyman AA. Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes. Proceedings of the National Academy of Sciences of the United States of America. 108: 4334-9. PMID 21368180 DOI: 10.1073/Pnas.1017150108  0.708
2011 Dumont S, Salmon ED, Mitchison TJ. Separate Locations of the Active and Passive Microtubule Interfaces in Kinetochores Inferred from Direction-Dependent Structural Changes Biophysical Journal. 100: 514a. DOI: 10.1016/J.Bpj.2010.12.3008  0.41
2010 Huang HC, Mitchison TJ, Shi J. Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest. Plos One. 5: e15724. PMID 21203573 DOI: 10.1371/Journal.Pone.0015724  0.592
2010 Mitchison TJ. Remaining mysteries of the cytoplasm. Molecular Biology of the Cell. 21: 3811-2. PMID 21079024 DOI: 10.1091/Mbc.E10-02-0084  0.329
2010 Wühr M, Tan ES, Parker SK, Detrich HW, Mitchison TJ. A model for cleavage plane determination in early amphibian and fish embryos. Current Biology : Cb. 20: 2040-5. PMID 21055946 DOI: 10.1016/J.Cub.2010.10.024  0.823
2010 Kueh HY, Brieher WM, Mitchison TJ. Quantitative analysis of actin turnover in Listeria comet tails: evidence for catastrophic filament turnover. Biophysical Journal. 99: 2153-62. PMID 20923649 DOI: 10.1016/J.Bpj.2010.07.038  0.765
2010 Huang HC, Shi J, Orth JD, Mitchison TJ. Cell death when the SAC is out of commission. Cell Cycle (Georgetown, Tex.). 9: 2049-50. PMID 20559025 DOI: 10.4161/Cc.9.11.11918  0.539
2010 Martin DS, Fathi R, Mitchison TJ, Gelles J. FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry. Proceedings of the National Academy of Sciences of the United States of America. 107: 5453-8. PMID 20212149 DOI: 10.1073/Pnas.0914924107  0.347
2010 Gatlin JC, Matov A, Danuser G, Mitchison TJ, Salmon ED. Directly probing the mechanical properties of the spindle and its matrix. The Journal of Cell Biology. 188: 481-9. PMID 20176922 DOI: 10.1083/Jcb.200907110  0.431
2010 Needleman DJ, Groen A, Ohi R, Maresca T, Mirny L, Mitchison T. Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules. Molecular Biology of the Cell. 21: 323-33. PMID 19940016 DOI: 10.1091/Mbc.E09-09-0816  0.83
2010 Ozlü N, Monigatti F, Renard BY, Field CM, Steen H, Mitchison TJ, Steen JJ. Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition. Molecular & Cellular Proteomics : McP. 9: 336-50. PMID 19786723 DOI: 10.1074/Mcp.M900308-Mcp200  0.699
2009 Dumont S, Mitchison TJ. Force and length in the mitotic spindle. Current Biology : Cb. 19: R749-61. PMID 19906577 DOI: 10.1016/J.Cub.2009.07.028  0.337
2009 Tsui M, Xie T, Orth JD, Carpenter AE, Rudnicki S, Kim S, Shamu CE, Mitchison TJ. An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor. Plos One. 4: e7339. PMID 19802393 DOI: 10.1371/Journal.Pone.0007339  0.332
2009 Huang HC, Shi J, Orth JD, Mitchison TJ. Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. Cancer Cell. 16: 347-58. PMID 19800579 DOI: 10.1016/J.Ccr.2009.08.020  0.614
2009 Chang P, Coughlin M, Mitchison TJ. Interaction between Poly(ADP-ribose) and NuMA contributes to mitotic spindle pole assembly. Molecular Biology of the Cell. 20: 4575-85. PMID 19759176 DOI: 10.1091/Mbc.E09-06-0477  0.576
2009 Kueh HY, Mitchison TJ. Structural plasticity in actin and tubulin polymer dynamics. Science (New York, N.Y.). 325: 960-3. PMID 19696342 DOI: 10.1126/Science.1168823  0.729
2009 Charras GT, Mitchison TJ, Mahadevan L. Animal cell hydraulics. Journal of Cell Science. 122: 3233-41. PMID 19690051 DOI: 10.1242/Jcs.049262  0.335
2009 Maresca TJ, Groen AC, Gatlin JC, Ohi R, Mitchison TJ, Salmon ED. Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity. Current Biology : Cb. 19: 1210-5. PMID 19540121 DOI: 10.1016/J.Cub.2009.05.061  0.766
2009 Dumont S, Mitchison TJ. Compression regulates mitotic spindle length by a mechanochemical switch at the poles. Current Biology : Cb. 19: 1086-95. PMID 19540117 DOI: 10.1016/J.Cub.2009.05.056  0.404
2009 Needleman DJ, Xu Y, Mitchison TJ. Pin-hole array correlation imaging: highly parallel fluorescence correlation spectroscopy. Biophysical Journal. 96: 5050-9. PMID 19527665 DOI: 10.1016/J.Bpj.2009.03.023  0.728
2009 Wühr M, Mitchison TJ, Field CM. Size and speed go hand in hand in cytokinesis. Cell. 137: 798-800. PMID 19490886 DOI: 10.1016/J.Cell.2009.05.012  0.789
2009 Groen AC, Maresca TJ, Gatlin JC, Salmon ED, Mitchison TJ. Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly. Molecular Biology of the Cell. 20: 2766-73. PMID 19369413 DOI: 10.1091/Mbc.E09-01-0043  0.756
2009 Wühr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ. How does a millimeter-sized cell find its center? Cell Cycle (Georgetown, Tex.). 8: 1115-21. PMID 19282671 DOI: 10.4161/Cc.8.8.8150  0.828
2009 Gatlin JC, Matov A, Groen AC, Needleman DJ, Maresca TJ, Danuser G, Mitchison TJ, Salmon ED. Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules. Current Biology : Cb. 19: 287-96. PMID 19230671 DOI: 10.1016/J.Cub.2009.01.055  0.838
2009 Dumont S, Mitchison TJ. Response of the Mitotic Spindle to Mechanical Force Biophysical Journal. 96: 505a. DOI: 10.1016/J.Bpj.2008.12.2603  0.445
2008 Orth JD, Tang Y, Shi J, Loy CT, Amendt C, Wilm C, Zenke FT, Mitchison TJ. Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Molecular Cancer Therapeutics. 7: 3480-9. PMID 18974392 DOI: 10.1158/1535-7163.Mct-08-0684  0.335
2008 Maloney KN, Fujita M, Eggert US, Schroeder FC, Field CM, Mitchison TJ, Clardy J. Actin-aggregating cucurbitacins from Physocarpus capitatus. Journal of Natural Products. 71: 1927-9. PMID 18959442 DOI: 10.1021/Np8005259  0.764
2008 Wühr M, Mitchison TJ, Field CM. Mitosis: new roles for myosin-X and actin at the spindle. Current Biology : Cb. 18: R912-4. PMID 18957236 DOI: 10.1016/J.Cub.2008.08.043  0.826
2008 Kueh HY, Brieher WM, Mitchison TJ. Dynamic stabilization of actin filaments. Proceedings of the National Academy of Sciences of the United States of America. 105: 16531-6. PMID 18931306 DOI: 10.1073/Pnas.0807394105  0.747
2008 Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Current Biology : Cb. 18: 1256-61. PMID 18718761 DOI: 10.1016/J.Cub.2008.07.092  0.821
2008 Kueh HY, Charras GT, Mitchison TJ, Brieher WM. Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers. The Journal of Cell Biology. 182: 341-53. PMID 18663144 DOI: 10.1083/Jcb.200801027  0.762
2008 Groen AC, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison TJ. A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. Journal of Cell Science. 121: 2293-300. PMID 18559893 DOI: 10.1242/Jcs.024018  0.823
2008 Shi J, Orth JD, Mitchison T. Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5 Cancer Research. 68: 3269-3276. PMID 18451153 DOI: 10.1158/0008-5472.Can-07-6699  0.336
2008 Hu CK, Coughlin M, Field CM, Mitchison TJ. Cell polarization during monopolar cytokinesis. The Journal of Cell Biology. 181: 195-202. PMID 18411311 DOI: 10.1083/Jcb.200711105  0.78
2008 Niethammer P, Kueh HY, Mitchison TJ. Spatial patterning of metabolism by mitochondria, oxygen, and energy sinks in a model cytoplasm. Current Biology : Cb. 18: 586-91. PMID 18406136 DOI: 10.1016/J.Cub.2008.03.038  0.708
2008 Mitchison TJ, Charras GT, Mahadevan L. Implications of a poroelastic cytoplasm for the dynamics of animal cell shape. Seminars in Cell & Developmental Biology. 19: 215-23. PMID 18395478 DOI: 10.1016/J.Semcdb.2008.01.008  0.395
2008 Salic A, Mitchison TJ. A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 2415-20. PMID 18272492 DOI: 10.1073/Pnas.0712168105  0.657
2008 Galkin VE, Orlova A, Brieher W, Kueh HY, Mitchison TJ, Egelman EH. Coronin-1A stabilizes F-actin by bridging adjacent actin protomers and stapling opposite strands of the actin filament. Journal of Molecular Biology. 376: 607-13. PMID 18177666 DOI: 10.1016/J.Jmb.2007.12.007  0.73
2008 Charras GT, Coughlin M, Mitchison TJ, Mahadevan L. Life and times of a cellular bleb. Biophysical Journal. 94: 1836-53. PMID 17921219 DOI: 10.1529/Biophysj.107.113605  0.33
2007 Irimia D, Charras G, Agrawal N, Mitchison T, Toner M. Polar stimulation and constrained cell migration in microfluidic channels. Lab On a Chip. 7: 1783-90. PMID 18030401 DOI: 10.1039/B710524J  0.318
2007 Burbank KS, Mitchison TJ, Fisher DS. Slide-and-cluster models for spindle assembly. Current Biology : Cb. 17: 1373-83. PMID 17702580 DOI: 10.1016/J.Cub.2007.07.058  0.396
2007 Vrabioiu AM, Mitchison TJ. Symmetry of septin hourglass and ring structures. Journal of Molecular Biology. 372: 37-49. PMID 17628594 DOI: 10.1016/J.Jmb.2007.05.100  0.808
2007 Ohi R, Burbank K, Liu Q, Mitchison TJ. Nonredundant functions of Kinesin-13s during meiotic spindle assembly. Current Biology : Cb. 17: 953-9. PMID 17509883 DOI: 10.1016/J.Cub.2007.04.057  0.5
2007 Li J, Brieher WM, Scimone ML, Kang SJ, Zhu H, Yin H, von Andrian UH, Mitchison T, Yuan J. Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization. Nature Cell Biology. 9: 276-86. PMID 17293856 DOI: 10.1038/Ncb1541  0.385
2006 Charras GT, Hu CK, Coughlin M, Mitchison TJ. Reassembly of contractile actin cortex in cell blebs. The Journal of Cell Biology. 175: 477-90. PMID 17088428 DOI: 10.1083/Jcb.200602085  0.61
2006 Burbank KS, Groen AC, Perlman ZE, Fisher DS, Mitchison TJ. A new method reveals microtubule minus ends throughout the meiotic spindle. The Journal of Cell Biology. 175: 369-75. PMID 17088423 DOI: 10.1083/Jcb.200511112  0.822
2006 Ribbeck K, Mitchison TJ. Meiotic spindle: sculpted by severing. Current Biology : Cb. 16: R923-5. PMID 17084690 DOI: 10.1016/J.Cub.2006.09.048  0.409
2006 Brieher WM, Kueh HY, Ballif BA, Mitchison TJ. Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1. The Journal of Cell Biology. 175: 315-24. PMID 17060499 DOI: 10.1083/Jcb.200603149  0.758
2006 Vrabioiu AM, Mitchison TJ. Structural insights into yeast septin organization from polarized fluorescence microscopy. Nature. 443: 466-9. PMID 17006515 DOI: 10.1038/Nature05109  0.821
2006 Eggert US, Field CM, Mitchison TJ. Small molecules in an RNAi world. Molecular Biosystems. 2: 93-6. PMID 16880926 DOI: 10.1039/B515335B  0.741
2006 Burbank KS, Mitchison TJ. Microtubule dynamic instability. Current Biology : Cb. 16: R516-7. PMID 16860721 DOI: 10.1016/J.Cub.2006.06.044  0.494
2006 Eggert US, Mitchison TJ, Field CM. Animal cytokinesis: from parts list to mechanisms. Annual Review of Biochemistry. 75: 543-66. PMID 16756502 DOI: 10.1146/Annurev.Biochem.74.082803.133425  0.792
2006 Eggert US, Mitchison TJ. Small molecule screening by imaging. Current Opinion in Chemical Biology. 10: 232-7. PMID 16682248 DOI: 10.1016/J.Cbpa.2006.04.010  0.678
2006 Ribbeck K, Groen AC, Santarella R, Bohnsack MT, Raemaekers T, Köcher T, Gentzel M, Görlich D, Wilm M, Carmeliet G, Mitchison TJ, Ellenberg J, Hoenger A, Mattaj IW. NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Molecular Biology of the Cell. 17: 2646-60. PMID 16571672 DOI: 10.1091/Mbc.E05-12-1178  0.777
2006 Maliga Z, Mitchison TJ. Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol. Bmc Chemical Biology. 6: 2. PMID 16504166 DOI: 10.1186/1472-6769-6-2  0.701
2005 Chang P, Coughlin M, Mitchison TJ. Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nature Cell Biology. 7: 1133-9. PMID 16244666 DOI: 10.1038/Ncb1322  0.621
2005 Mahadevan L, Mitchison TJ. Cell biology: powerful curves. Nature. 435: 895-7. PMID 15959501 DOI: 10.1038/435895A  0.373
2005 Dorer RK, Zhong S, Tallarico JA, Wong WH, Mitchison TJ, Murray AW. A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes. Current Biology : Cb. 15: 1070-6. PMID 15936280 DOI: 10.1016/J.Cub.2005.05.020  0.544
2005 Charras GT, Yarrow JC, Horton MA, Mahadevan L, Mitchison TJ. Non-equilibration of hydrostatic pressure in blebbing cells. Nature. 435: 365-9. PMID 15902261 DOI: 10.1038/Nature03550  0.786
2005 Mitchison TJ. Mechanism and function of poleward flux in Xenopus extract meiotic spindles. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 360: 623-9. PMID 15897184 DOI: 10.1098/Rstb.2004.1616  0.402
2005 Yarrow JC, Totsukawa G, Charras GT, Mitchison TJ. Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor. Chemistry & Biology. 12: 385-95. PMID 15797222 DOI: 10.1016/J.Chembiol.2005.01.015  0.791
2005 Mitchison TJ, Maddox P, Gaetz J, Groen A, Shirasu M, Desai A, Salmon ED, Kapoor TM. Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles. Molecular Biology of the Cell. 16: 3064-76. PMID 15788560 DOI: 10.1091/Mbc.E05-02-0174  0.826
2005 Perlman ZE, Mitchison TJ, Mayer TU. High-content screening and profiling of drug activity in an automated centrosome-duplication assay. Chembiochem : a European Journal of Chemical Biology. 6: 145-51. PMID 15568197 DOI: 10.1002/Cbic.200400266  0.806
2005 Valentine MT, Perlman ZE, Mitchison TJ, Weitz DA. Mechanical properties of Xenopus egg cytoplasmic extracts. Biophysical Journal. 88: 680-9. PMID 15501931 DOI: 10.1529/Biophysj.104.048025  0.807
2005 Straight AF, Field CM, Mitchison TJ. Anillin binds nonmuscle myosin II and regulates the contractile ring. Molecular Biology of the Cell. 16: 193-201. PMID 15496454 DOI: 10.1091/Mbc.E04-08-0758  0.753
2005 Vrabioiu A, Mitchison T. Towards an Understanding of Yeast Septins' Organization In Vivo Microscopy and Microanalysis. 11. DOI: 10.1017/S1431927605501399  0.777
2005 Lucas-Lopez C, Patterson S, Blum T, Straight AF, Toth J, Slawin AMZ, Mitchison TJ, Sellers JR, Westwood NJ. Absolute stereochemical assignment and fluorescence tuning of the small molecule tool, (-)-blebbistatin European Journal of Organic Chemistry. 1736-1740. DOI: 10.1002/Ejoc.200500103  0.62
2004 Miyamoto DT, Perlman ZE, Burbank KS, Groen AC, Mitchison TJ. The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles. The Journal of Cell Biology. 167: 813-8. PMID 15583027 DOI: 10.1083/Jcb.200407126  0.818
2004 Chang P, Jacobson MK, Mitchison TJ. Poly(ADP-ribose) is required for spindle assembly and structure. Nature. 432: 645-9. PMID 15577915 DOI: 10.1038/Nature03061  0.629
2004 Limouze J, Straight AF, Mitchison T, Sellers JR. Specificity of blebbistatin, an inhibitor of myosin II. Journal of Muscle Research and Cell Motility. 25: 337-41. PMID 15548862 DOI: 10.1007/S10974-004-6060-7  0.627
2004 Eggert US, Kiger AA, Richter C, Perlman ZE, Perrimon N, Mitchison TJ, Field CM. Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. Plos Biology. 2: e379. PMID 15547975 DOI: 10.1371/Journal.Pbio.0020379  0.786
2004 Ramamurthy B, Yengo CM, Straight AF, Mitchison TJ, Sweeney HL. Kinetic mechanism of blebbistatin inhibition of nonmuscle myosin IIb. Biochemistry. 43: 14832-9. PMID 15544354 DOI: 10.1021/Bi0490284  0.649
2004 Perlman ZE, Slack MD, Feng Y, Mitchison TJ, Wu LF, Altschuler SJ. Multidimensional drug profiling by automated microscopy. Science (New York, N.Y.). 306: 1194-8. PMID 15539606 DOI: 10.1126/Science.1100709  0.773
2004 Shirasu-Hiza M, Perlman ZE, Wittmann T, Karsenti E, Mitchison TJ. Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked. Current Biology : Cb. 14: 1941-5. PMID 15530396 DOI: 10.1016/J.Cub.2004.10.029  0.829
2004 Groen AC, Cameron LA, Coughlin M, Miyamoto DT, Mitchison TJ, Ohi R. XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. Current Biology : Cb. 14: 1801-11. PMID 15498487 DOI: 10.1016/J.Cub.2004.10.002  0.838
2004 Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, et al. A standardized kinesin nomenclature. The Journal of Cell Biology. 167: 19-22. PMID 15479732 DOI: 10.1083/Jcb.200408113  0.665
2004 Mitchison TJ, Maddox P, Groen A, Cameron L, Perlman Z, Ohi R, Desai A, Salmon ED, Kapoor TM. Bipolarization and poleward flux correlate during Xenopus extract spindle assembly. Molecular Biology of the Cell. 15: 5603-15. PMID 15385629 DOI: 10.1091/Mbc.E04-05-0440  0.809
2004 Yarrow JC, Perlman ZE, Westwood NJ, Mitchison TJ. A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. Bmc Biotechnology. 4: 21. PMID 15357872 DOI: 10.1186/1472-6750-4-21  0.793
2004 Salic A, Waters JC, Mitchison TJ. Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell. 118: 567-78. PMID 15339662 DOI: 10.1016/J.Cell.2004.08.016  0.741
2004 Margalit DN, Romberg L, Mets RB, Hebert AM, Mitchison TJ, Kirschner MW, RayChaudhuri D. Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality. Proceedings of the National Academy of Sciences of the United States of America. 101: 11821-6. PMID 15289600 DOI: 10.1073/Pnas.0404439101  0.678
2004 Valentine MT, Perlman ZE, Gardel ML, Shin JH, Matsudaira P, Mitchison TJ, Weitz DA. Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials. Biophysical Journal. 86: 4004-14. PMID 15189896 DOI: 10.1529/Biophysj.103.037812  0.761
2004 Venkatesh N, Feng Y, DeDecker B, Yacono P, Golan D, Mitchison T, McKeon F. Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression. Proceedings of the National Academy of Sciences of the United States of America. 101: 8969-74. PMID 15184684 DOI: 10.1073/Pnas.0402803101  0.583
2004 Brieher WM, Coughlin M, Mitchison TJ. Fascin-mediated propulsion of Listeria monocytogenes independent of frequent nucleation by the Arp2/3 complex. The Journal of Cell Biology. 165: 233-42. PMID 15117967 DOI: 10.1083/Jcb.200311040  0.383
2004 Ohi R, Sapra T, Howard J, Mitchison TJ. Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation. Molecular Biology of the Cell. 15: 2895-906. PMID 15064354 DOI: 10.1091/Mbc.E04-02-0082  0.429
2004 Corcoran LJ, Mitchison TJ, Liu Q. A novel action of histone deacetylase inhibitors in a protein aggresome disease model. Current Biology : Cb. 14: 488-92. PMID 15043813 DOI: 10.1016/J.Cub.2004.03.003  0.361
2004 Tirnauer JS, Salmon ED, Mitchison TJ. Microtubule plus-end dynamics in Xenopus egg extract spindles. Molecular Biology of the Cell. 15: 1776-84. PMID 14767058 DOI: 10.1091/Mbc.E03-11-0824  0.461
2004 Romberg L, Mitchison TJ. Rate-limiting guanosine 5'-triphosphate hydrolysis during nucleotide turnover by FtsZ, a prokaryotic tubulin homologue involved in bacterial cell division. Biochemistry. 43: 282-8. PMID 14705956 DOI: 10.1021/Bi035465R  0.35
2004 Vrabioiu AM, Gerber SA, Gygi SP, Field CM, Mitchison TJ. The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. The Journal of Biological Chemistry. 279: 3111-8. PMID 14597621 DOI: 10.1074/Jbc.M310941200  0.791
2004 Margalit DN, Romberg L, Mets RB, Hebert AM, Mitchison TJ, Kirschner MW, RayChaudhuri D. Erratum: Targeting cell division: Small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality (Proceedings of the National Academy of Sciences of the United States of America (August 10, 2004) 101, 32 (11821-11826)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0405755101  0.622
2003 Miyamoto DT, Perlman ZE, Mitchison TJ, Shirasu-Hiza M. Dynamics of the mitotic spindle--potential therapeutic targets. Progress in Cell Cycle Research. 5: 349-60. PMID 14593729  0.821
2003 Ohi R, Coughlin ML, Lane WS, Mitchison TJ. An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin. Developmental Cell. 5: 309-21. PMID 12919681 DOI: 10.1016/S1534-5807(03)00229-6  0.476
2003 Canman JC, Cameron LA, Maddox PS, Straight A, Tirnauer JS, Mitchison TJ, Fang G, Kapoor TM, Salmon ED. Determining the position of the cell division plane. Nature. 424: 1074-8. PMID 12904818 DOI: 10.1038/Nature01860  0.83
2003 Maddox P, Straight A, Coughlin P, Mitchison TJ, Salmon ED. Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics. The Journal of Cell Biology. 162: 377-82. PMID 12900391 DOI: 10.1083/Jcb.200301088  0.784
2003 Xu J, Wang F, Van Keymeulen A, Herzmark P, Straight A, Kelly K, Takuwa Y, Sugimoto N, Mitchison T, Bourne HR. Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell. 114: 201-14. PMID 12887922 DOI: 10.1016/S0092-8674(03)00555-5  0.672
2003 Yarrow JC, Lechler T, Li R, Mitchison TJ. Rapid de-localization of actin leading edge components with BDM treatment. Bmc Cell Biology. 4: 5. PMID 12783627 DOI: 10.1186/1471-2121-4-5  0.813
2003 Yarrow JC, Feng Y, Perlman ZE, Kirchhausen T, Mitchison TJ. Phenotypic screening of small molecule libraries by high throughput cell imaging. Combinatorial Chemistry & High Throughput Screening. 6: 279-86. PMID 12769670 DOI: 10.2174/138620703106298527  0.786
2003 Shirasu-Hiza M, Coughlin P, Mitchison T. Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification. The Journal of Cell Biology. 161: 349-58. PMID 12719474 DOI: 10.1083/Jcb.200211095  0.766
2003 Straight AF, Cheung A, Limouze J, Chen I, Westwood NJ, Sellers JR, Mitchison TJ. Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science (New York, N.Y.). 299: 1743-7. PMID 12637748 DOI: 10.1126/Science.1081412  0.688
2003 McGrath JL, Eungdamrong NJ, Fisher CI, Peng F, Mahadevan L, Mitchison TJ, Kuo SC. The force-velocity relationship for the actin-based motility of Listeria monocytogenes. Current Biology : Cb. 13: 329-32. PMID 12593799 DOI: 10.1016/S0960-9822(03)00051-4  0.791
2002 Kinoshita M, Field CM, Coughlin ML, Straight AF, Mitchison TJ. Self- and actin-templated assembly of Mammalian septins. Developmental Cell. 3: 791-802. PMID 12479805 DOI: 10.1016/S1534-5807(02)00366-0  0.786
2002 Tirnauer JS, Canman JC, Salmon ED, Mitchison TJ. EB1 targets to kinetochores with attached, polymerizing microtubules. Molecular Biology of the Cell. 13: 4308-16. PMID 12475954 DOI: 10.1091/Mbc.E02-04-0236  0.468
2002 Macara IG, Baldarelli R, Field CM, Glotzer M, Hayashi Y, Hsu SC, Kennedy MB, Kinoshita M, Longtine M, Low C, Maltais LJ, McKenzie L, Mitchison TJ, Nishikawa T, Noda M, et al. Mammalian septins nomenclature. Molecular Biology of the Cell. 13: 4111-3. PMID 12475938 DOI: 10.1091/Mbc.E02-07-0438  0.715
2002 Mitchison TJ, Field CM. Cytoskeleton: what does GTP do for septins? Current Biology : Cb. 12: R788-90. PMID 12445407 DOI: 10.1016/S0960-9822(02)01295-2  0.663
2002 Walczak CE, Gan EC, Desai A, Mitchison TJ, Kline-Smith SL. The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly. Current Biology : Cb. 12: 1885-9. PMID 12419191 DOI: 10.1016/S0960-9822(02)01227-7  0.823
2002 Tirnauer JS, Grego S, Salmon ED, Mitchison TJ. EB1-microtubule interactions in Xenopus egg extracts: role of EB1 in microtubule stabilization and mechanisms of targeting to microtubules. Molecular Biology of the Cell. 13: 3614-26. PMID 12388761 DOI: 10.1091/Mbc.E02-04-0210  0.475
2002 Maddox P, Desai A, Oegema K, Mitchison TJ, Salmon ED. Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos. Current Biology : Cb. 12: 1670-4. PMID 12361570 DOI: 10.1016/S0960-9822(02)01183-1  0.796
2002 Maliga Z, Kapoor TM, Mitchison TJ. Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. Chemistry & Biology. 9: 989-96. PMID 12323373 DOI: 10.1016/S1074-5521(02)00212-0  0.788
2002 Watanabe N, Mitchison TJ. Single-molecule speckle analysis of actin filament turnover in lamellipodia. Science (New York, N.Y.). 295: 1083-6. PMID 11834838 DOI: 10.1126/Science.1067470  0.419
2002 Cheung A, Dantzig JA, Hollingworth S, Baylor SM, Goldman YE, Mitchison TJ, Straight AF. A small-molecule inhibitor of skeletal muscle myosin II. Nature Cell Biology. 4: 83-8. PMID 11744924 DOI: 10.1038/Ncb734  0.624
2002 McDonald WH, Ohi R, Miyamoto DT, Mitchison TJ, Yates JR. Comparison of three directly coupled HPLC MS/MS strategies for identification of proteins from complex mixtures: Single-dimension LC-MS/MS, 2-phase MudPIT, and 3-phase MudPIT International Journal of Mass Spectrometry. 219: 245-251. DOI: 10.1016/S1387-3806(02)00563-8  0.607
2001 Kapoor TM, Mitchison TJ. Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix. The Journal of Cell Biology. 154: 1125-33. PMID 11564753 DOI: 10.1083/Jcb.200106011  0.642
2001 Peterson JR, Lokey RS, Mitchison TJ, Kirschner MW. A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions. Proceedings of the National Academy of Sciences of the United States of America. 98: 10624-9. PMID 11553809 DOI: 10.1073/Pnas.201393198  0.775
2001 Mitchison TJ, Salmon ED. Mitosis: a history of division. Nature Cell Biology. 3: E17-21. PMID 11146645 DOI: 10.1038/35050656  0.347
2000 Kapoor TM, Mayer TU, Coughlin ML, Mitchison TJ. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. The Journal of Cell Biology. 150: 975-88. PMID 10973989 DOI: 10.1083/Jcb.150.5.975  0.783
2000 Oegema K, Savoian MS, Mitchison TJ, Field CM. Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis. The Journal of Cell Biology. 150: 539-52. PMID 10931866 DOI: 10.1083/Jcb.150.3.539  0.779
2000 Haggarty SJ, Mayer TU, Miyamoto DT, Fathi R, King RW, Mitchison TJ, Schreiber SL. Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis. Chemistry & Biology. 7: 275-86. PMID 10780927 DOI: 10.1016/S1074-5521(00)00101-0  0.813
2000 Taunton J, Rowning BA, Coughlin ML, Wu M, Moon RT, Mitchison TJ, Larabell CA. Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP. The Journal of Cell Biology. 148: 519-30. PMID 10662777 DOI: 10.1083/Jcb.148.3.519  0.639
2000 Rotella DP, Mayer TU, Kapoor TM, Haggarty SJ, King RW, Schreiber SL, Mitchison TJ. Small-molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen Chemtracts. 13: 256-258.  0.645
1999 Mallavarapu A, Sawin K, Mitchison T. A switch in microtubule dynamics at the onset of anaphase B in the mitotic spindle of Schizosaccharomyces pombe. Current Biology : Cb. 9: 1423-6. PMID 10607565 DOI: 10.1016/S0960-9822(00)80090-1  0.479
1999 Maddox P, Desai A, Salmon ED, Mitchison TJ, Oogema K, Kapoor T, Matsumoto B, Inoué S. Dynamic confocal imaging of mitochondria in swimming Tetrahymena and of microtubule poleward flux in Xenopus extract spindles. The Biological Bulletin. 197: 263-5. PMID 10573847 DOI: 10.2307/1542641  0.755
1999 Weiner OD, Servant G, Welch MD, Mitchison TJ, Sedat JW, Bourne HR. Spatial control of actin polymerization during neutrophil chemotaxis. Nature Cell Biology. 1: 75-81. PMID 10559877 DOI: 10.1038/10042  0.802
1999 Mayer TU, Kapoor TM, Haggarty SJ, King RW, Schreiber SL, Mitchison TJ. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science (New York, N.Y.). 286: 971-4. PMID 10542155 DOI: 10.1126/Science.286.5441.971  0.814
1999 Mallavarapu A, Mitchison T. Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction. The Journal of Cell Biology. 146: 1097-106. PMID 10477762 DOI: 10.1083/Jcb.146.5.1097  0.397
1999 Kapoor TM, Mitchison TJ. Allele-specific activators and inhibitors for kinesin. Proceedings of the National Academy of Sciences of the United States of America. 96: 9106-11. PMID 10430903 DOI: 10.1073/Pnas.96.16.9106  0.622
1999 Oegema K, Wiese C, Martin OC, Milligan RA, Iwamatsu A, Mitchison TJ, Zheng Y. Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules. The Journal of Cell Biology. 144: 721-33. PMID 10037793 DOI: 10.1083/Jcb.144.4.721  0.758
1999 Desai A, Verma S, Mitchison TJ, Walczak CE. Kin I kinesins are microtubule-destabilizing enzymes. Cell. 96: 69-78. PMID 9989498 DOI: 10.1016/S0092-8674(00)80960-5  0.748
1999 Desai A, Murray A, Mitchison TJ, Walczak CE. The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods in Cell Biology. 61: 385-412. PMID 9891325 DOI: 10.1016/S0091-679X(08)61991-3  0.759
1999 Sharp DJ, McDonald KL, Brown HM, Matthies HJ, Walczak C, Vale RD, Mitchison TJ, Scholey JM. The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. The Journal of Cell Biology. 144: 125-38. PMID 9885249 DOI: 10.1083/Jcb.144.1.125  0.695
1998 Frazier JA, Wong ML, Longtine MS, Pringle JR, Mann M, Mitchison TJ, Field C. Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function. The Journal of Cell Biology. 143: 737-49. PMID 9813094 DOI: 10.1083/Jcb.143.3.737  0.698
1998 Field CM, Oegema K, Zheng Y, Mitchison TJ, Walczak CE. Purification of cytoskeletal proteins using peptide antibodies. Methods in Enzymology. 298: 525-41. PMID 9751906 DOI: 10.1016/S0076-6879(98)98043-0  0.761
1998 Oegema K, Desai A, Wong ML, Mitchison TJ, Field CM. Purification and assay of a septin complex from Drosophila embryos. Methods in Enzymology. 298: 279-95. PMID 9751888 DOI: 10.1016/S0076-6879(98)98025-9  0.757
1998 Zheng Y, Wong ML, Alberts B, Mitchison T. [19] Purification and assay of γ tubulin ring complex Methods in Enzymology. 298: 218-228. PMID 9751884 DOI: 10.1016/S0076-6879(98)98021-1  0.59
1998 Desai A, Mitchison TJ. Preparation and characterization of caged fluorescein tubulin. Methods in Enzymology. 298: 125-32. PMID 9751877 DOI: 10.1016/S0076-6879(98)98014-4  0.504
1998 Welch MD, Mitchison TJ. Purification and assay of the platelet Arp2/3 complex. Methods in Enzymology. 298: 52-61. PMID 9751871 DOI: 10.1016/S0076-6879(98)98008-9  0.509
1998 Desai A, Mitchison TJ. Tubulin and FtsZ structures: functional and therapeutic implications. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 523-7. PMID 9722999 DOI: 10.1002/(Sici)1521-1878(199807)20:7<523::Aid-Bies1>3.0.Co;2-L  0.553
1998 Walczak CE, Vernos I, Mitchison TJ, Karsenti E, Heald R. A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity. Current Biology : Cb. 8: 903-13. PMID 9707401 DOI: 10.1016/S0960-9822(07)00370-3  0.777
1998 Mitchison TJ, Sawin KE, Theriot JA, Gee K, Mallavarapu A. Caged fluorescent probes. Methods in Enzymology. 291: 63-78. PMID 9661145 DOI: 10.1016/S0076-6879(98)91007-2  0.55
1998 Welch MD, Rosenblatt J, Skoble J, Portnoy DA, Mitchison TJ. Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation. Science (New York, N.Y.). 281: 105-8. PMID 9651243 DOI: 10.1126/Science.281.5373.105  0.626
1998 Desai A, Maddox PS, Mitchison TJ, Salmon ED. Anaphase A chromosome movement and poleward spindle microtubule flux occur At similar rates in Xenopus extract spindles. The Journal of Cell Biology. 141: 703-13. PMID 9566970 DOI: 10.1083/Jcb.141.3.703  0.723
1997 Desai A, Mitchison TJ. Microtubule polymerization dynamics. Annual Review of Cell and Developmental Biology. 13: 83-117. PMID 9442869 DOI: 10.1146/Annurev.Cellbio.13.1.83  0.569
1997 Desai A, Deacon HW, Walczak CE, Mitchison TJ. A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts. Proceedings of the National Academy of Sciences of the United States of America. 94: 12378-83. PMID 9356457 DOI: 10.1073/Pnas.94.23.12378  0.753
1997 Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. The Journal of Cell Biology. 138: 375-84. PMID 9230079 DOI: 10.1083/Jcb.138.2.375  0.6
1997 Oegema K, Mitchison TJ. Rappaport rules: cleavage furrow induction in animal cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 4817-20. PMID 9144146 DOI: 10.1073/Pnas.94.10.4817  0.639
1997 Rosenblatt J, Agnew BJ, Abe H, Bamburg JR, Mitchison TJ. Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails. The Journal of Cell Biology. 136: 1323-32. PMID 9087446 DOI: 10.1083/Jcb.136.6.1323  0.457
1997 Cramer LP, Siebert M, Mitchison TJ. Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: implications for the generation of motile force. The Journal of Cell Biology. 136: 1287-305. PMID 9087444 DOI: 10.1083/Jcb.136.6.1287  0.425
1997 Walczak CE, Verma S, Mitchison TJ. XCTK2: a kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts. The Journal of Cell Biology. 136: 859-70. PMID 9049251 DOI: 10.1083/Jcb.136.4.859  0.682
1997 Cramer LP, Mitchison TJ. Investigation of the mechanism of retraction of the cell margin and rearward flow of nodules during mitotic cell rounding. Molecular Biology of the Cell. 8: 109-19. PMID 9017599 DOI: 10.1091/Mbc.8.1.109  0.387
1997 Welch MD, Mallavarapu A, Rosenblatt J, Mitchison TJ. Actin dynamics in vivo. Current Opinion in Cell Biology. 9: 54-61. PMID 9013669 DOI: 10.1016/S0955-0674(97)80152-4  0.637
1997 Welch MD, Iwamatsu A, Mitchison TJ. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. Nature. 385: 265-9. PMID 9000076 DOI: 10.1038/385265A0  0.641
1996 Waters JC, Mitchison TJ, Rieder CL, Salmon ED. The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work. Molecular Biology of the Cell. 7: 1547-58. PMID 8898361 DOI: 10.1091/Mbc.7.10.1547  0.464
1996 Walczak CE, Mitchison TJ. Kinesin-related proteins at mitotic spindle poles: function and regulation. Cell. 85: 943-6. PMID 8674121 DOI: 10.1016/S0092-8674(00)81295-7  0.677
1996 Field CM, al-Awar O, Rosenblatt J, Wong ML, Alberts B, Mitchison TJ. A purified Drosophila septin complex forms filaments and exhibits GTPase activity. The Journal of Cell Biology. 133: 605-16. PMID 8636235 DOI: 10.1083/Jcb.133.3.605  0.67
1996 Belmont LD, Mitchison TJ. Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules. Cell. 84: 623-31. PMID 8598048 DOI: 10.1016/S0092-8674(00)81037-5  0.45
1996 Walczak CE, Mitchison TJ, Desai A. XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly. Cell. 84: 37-47. PMID 8548824 DOI: 10.1016/S0092-8674(00)80991-5  0.763
1995 Mitchison TJ. Evolution of a dynamic cytoskeleton. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 349: 299-304. PMID 8577841 DOI: 10.1098/Rstb.1995.0117  0.409
1995 Zhen Y, Wong ML, Alberts B, Mitchison T. Nucleation of microtubule assembly by a γ-tubulin-containing ring complex Nature. 378: 578-583. PMID 8524390 DOI: 10.1038/378578A0  0.428
1995 Wordeman L, Mitchison TJ. Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. The Journal of Cell Biology. 128: 95-104. PMID 7822426 DOI: 10.1083/Jcb.128.1.95  0.365
1995 Desai A, Mitchison TJ. A new role for motor proteins as couplers to depolymerizing microtubules. The Journal of Cell Biology. 128: 1-4. PMID 7822407 DOI: 10.1083/Jcb.128.1.1  0.537
1995 Rosenblatt J, Peluso P, Mitchison TJ. The bulk of unpolymerized actin in Xenopus egg extracts is ATP-bound Molecular Biology of the Cell. 6: 227-236. PMID 7787248 DOI: 10.1091/Mbc.6.2.227  0.401
1995 Sawin KE, Mitchison TJ. Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. Proceedings of the National Academy of Sciences of the United States of America. 92: 4289-93. PMID 7753799 DOI: 10.1073/Pnas.92.10.4289  0.439
1995 Hirano T, Mitchison TJ, Swedlow JR. The SMC family: from chromosome condensation to dosage compensation. Current Opinion in Cell Biology. 7: 329-36. PMID 7662362 DOI: 10.1016/0955-0674(95)80087-5  0.607
1995 Cramer LP, Mitchison TJ. Myosin is involved in postmitotic cell spreading. The Journal of Cell Biology. 131: 179-89. PMID 7559774 DOI: 10.1083/Jcb.131.1.179  0.403
1994 Theriot JA, Rosenblatt J, Portnoy DA, Goldschmidt-Clermont PJ, Mitchison TJ. Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts. Cell. 76: 505-17. PMID 8313471 DOI: 10.1016/0092-8674(94)90114-7  0.616
1994 Cramer LP, Mitchison TJ, Theriot JA. Actin-dependent motile forces and cell motility. Current Opinion in Cell Biology. 6: 82-6. PMID 8167030 DOI: 10.1016/0955-0674(94)90120-1  0.639
1994 Sawin KE, Mitchison TJ. Microtubule flux in mitosis is independent of chromosomes, centrosomes, and antiparallel microtubules. Molecular Biology of the Cell. 5: 217-26. PMID 8019007 DOI: 10.1091/Mbc.5.2.217  0.458
1994 Hirano T, Mitchison TJ. A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro. Cell. 79: 449-58. PMID 7954811 DOI: 10.1016/0092-8674(94)90254-2  0.623
1994 Murray AW, Mitchison TJ. Mitosis. Kinetochores pass the IQ test. Current Biology : Cb. 4: 38-41. PMID 7922309 DOI: 10.1016/S0960-9822(00)00007-5  0.523
1993 Hirano T, Mitchison TJ. Topoisomerase II does not play a scaffolding role in the organization of mitotic chromosomes assembled in Xenopus egg extracts. The Journal of Cell Biology. 120: 601-12. PMID 8381118 DOI: 10.1083/Jcb.120.3.601  0.61
1993 Cramer L, Mitchison TJ. Moving and stationary actin filaments are involved in spreading of postmitotic PtK2 cells. The Journal of Cell Biology. 122: 833-43. PMID 8349733 DOI: 10.1083/Jcb.122.4.833  0.408
1993 Theriot JA, Mitchison TJ. The three faces of profilin. Cell. 75: 835-8. PMID 8252619 DOI: 10.1016/0092-8674(93)90527-W  0.663
1993 Hyman AA, Mitchison TJ. An assay for the activity of microtubule-based motors on the kinetochores of isolated Chinese hamster ovary chromosomes. Methods in Cell Biology. 39: 267-76. PMID 8246803 DOI: 10.1016/S0091-679X(08)60176-4  0.571
1993 Mitchison TJ. Localization of an exchangeable GTP binding site at the plus end of microtubules. Science (New York, N.Y.). 261: 1044-7. PMID 8102497 DOI: 10.1126/Science.8102497  0.375
1993 Mitchison TJ. Compare and contrast actin filaments and microtubules. Molecular Biology of the Cell. 3: 1309-15. PMID 1493331 DOI: 10.1091/Mbc.3.12.1309  0.42
1992 Theriot JA, Mitchison TJ. The nucleation-release model of actin filament dynamics in cell motility. Trends in Cell Biology. 2: 219-22. PMID 14731477 DOI: 10.1016/0962-8924(92)90298-2  0.637
1992 Hirano T, Mitchison TJ. Cell cycle control of higher-order chromatin assembly around naked DNA in vitro. The Journal of Cell Biology. 115: 1479-89. PMID 1661728 DOI: 10.1083/Jcb.115.6.1479  0.633
1992 Mitchison TJ. Actin based motility on retraction fibers in mitotic PtK2 cells. Cell Motility and the Cytoskeleton. 22: 135-51. PMID 1633624 DOI: 10.1002/Cm.970220207  0.351
1992 Theriot JA, Mitchison TJ, Tilney LG, Portnoy DA. The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization. Nature. 357: 257-60. PMID 1589024 DOI: 10.1038/357257A0  0.628
1992 Symons MH, Mitchison TJ. A GTPase controls cell-substrate adhesion in Xenopus XTC fibroblasts. The Journal of Cell Biology. 118: 1235-44. PMID 1512294 DOI: 10.1083/Jcb.118.5.1235  0.364
1992 Hyman AA, Salser S, Drechsel DN, Unwin N, Mitchison TJ. Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP. Molecular Biology of the Cell. 3: 1155-67. PMID 1421572 DOI: 10.1091/Mbc.3.10.1155  0.601
1992 Sawin KE, LeGuellec K, Philippe M, Mitchison TJ. Mitotic spindle organization by a plus-end-directed microtubule motor. Nature. 359: 540-3. PMID 1406972 DOI: 10.1038/359540A0  0.484
1992 Hyman AA, Middleton K, Centola M, Mitchison TJ, Carbon J. Microtubule-motor activity of a yeast centromere-binding protein complex. Nature. 359: 533-6. PMID 1406970 DOI: 10.1038/359533A0  0.595
1992 Mitchison TJ, Salmon ED. Poleward kinetochore fiber movement occurs during both metaphase and anaphase-A in newt lung cell mitosis. The Journal of Cell Biology. 119: 569-82. PMID 1400593 DOI: 10.1083/Jcb.119.3.569  0.408
1992 Theriot JA, Mitchison TJ. Comparison of actin and cell surface dynamics in motile fibroblasts. The Journal of Cell Biology. 119: 367-77. PMID 1400580 DOI: 10.1083/Jcb.119.2.367  0.624
1992 Mitchison TJ. Self-organization of polymer-motor systems in the cytoskeleton. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 336: 99-106. PMID 1351302 DOI: 10.1098/Rstb.1992.0049  0.412
1992 Hyman AA, Mitchison TJ. Molecular basis of chromosome movement Current Opinion in Structural Biology. 2: 275-279. DOI: 10.1016/0960-9822(92)90498-Y  0.5
1992 Hyman AA, Mitchison TJ. Molecular basis of chromosome movement: Current Opinion in Structural Biology 1992, 2:275–279 Current Opinion in Structural Biology. 2: 275-279. DOI: 10.1016/0959-440X(92)90157-3  0.389
1991 Theriot JA, Mitchison TJ. Actin microfilament dynamics in locomoting cells. Nature. 352: 126-31. PMID 2067574 DOI: 10.1038/352126A0  0.652
1991 Hyman AA, Mitchison TJ. Two different microtubule-based motor activities with opposite polarities in kinetochores. Nature. 351: 206-11. PMID 2041567 DOI: 10.1038/351206A0  0.557
1991 Hyman A, Drechsel D, Kellogg D, Salser S, Sawin K, Steffen P, Wordeman L, Mitchison T. Preparation of modified tubulins. Methods in Enzymology. 196: 478-85. PMID 2034137 DOI: 10.1016/0076-6879(91)96041-O  0.588
1991 Sawin KE, Mitchison TJ. Poleward microtubule flux mitotic spindles assembled in vitro. The Journal of Cell Biology. 112: 941-54. PMID 1999464 DOI: 10.1083/Jcb.112.5.941  0.471
1991 Sawin KE, Mitchison TJ. Mitotic spindle assembly by two different pathways in vitro. The Journal of Cell Biology. 112: 925-40. PMID 1999463 DOI: 10.1083/Jcb.112.5.925  0.482
1991 Symons MH, Mitchison TJ. Control of actin polymerization in live and permeabilized fibroblasts. The Journal of Cell Biology. 114: 503-13. PMID 1860882 DOI: 10.1083/Jcb.114.3.503  0.448
1991 Wordeman L, Steuer ER, Sheetz MP, Mitchison T. Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes. The Journal of Cell Biology. 114: 285-94. PMID 1830054 DOI: 10.1083/Jcb.114.2.285  0.437
1991 Hyman AA, Mitchison TJ. Regulation of the direction of chromosome movement. Cold Spring Harbor Symposia On Quantitative Biology. 56: 745-50. PMID 1819521 DOI: 10.1101/Sqb.1991.056.01.083  0.509
1991 Reinsch SS, Mitchison TJ, Kirschner M. Microtubule polymer assembly and transport during axonal elongation. The Journal of Cell Biology. 115: 365-79. PMID 1717484 DOI: 10.1083/Jcb.115.2.365  0.617
1990 Mitchison T, Kirschner M. Cytoskeletal dynamics and nerve growth. Neuron. 1: 761-72. PMID 3078414 DOI: 10.1016/0896-6273(88)90124-9  0.569
1990 Belmont LD, Hyman AA, Sawin KE, Mitchison TJ. Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts. Cell. 62: 579-89. PMID 2379239 DOI: 10.1016/0092-8674(90)90022-7  0.579
1990 Mitchison TJ. Mitosis. The kinetochore in captivity. Nature. 348: 14-5. PMID 2234053 DOI: 10.1038/348014A0  0.419
1990 Mitchison TJ, Sawin KE. Tubulin flux in the mitotic spindle: where does it come from, where is it going? Cell Motility and the Cytoskeleton. 16: 93-8. PMID 2198113 DOI: 10.1002/Cm.970160202  0.402
1990 Hyman AA, Mitchison TJ. Modulation of microtubule stability by kinetochores in vitro. The Journal of Cell Biology. 110: 1607-16. PMID 2186046 DOI: 10.1083/Jcb.110.5.1607  0.605
1990 Sawin K, Mitchison T. Cell biology. Motoring in the spindle. Nature. 345: 22-23. PMID 2139498 DOI: 10.1038/345022A0  0.348
1989 Mitchison TJ. Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence. The Journal of Cell Biology. 109: 637-52. PMID 2760109 DOI: 10.1083/Jcb.109.2.637  0.41
1988 Koshland DE, Mitchison TJ, Kirschner MW. Polewards chromosome movement driven by microtubule depolymerization in vitro. Nature. 331: 499-504. PMID 3340202 DOI: 10.1038/331499A0  0.754
1988 Mitchison T, Hyman A. Cell division. Kinetochores on the move. Nature. 336: 200-201. PMID 3194007 DOI: 10.1038/336200A0  0.575
1987 Mitchison TJ. The role of microtubule polarity in the movement of kinesin and kinetochores. Journal of Cell Science. Supplement. 5: 121-8. PMID 3115997 DOI: 10.1242/Jcs.1986.Supplement_5.7  0.366
1987 Mitchison TJ, Kirschner MW. Some thoughts on the partitioning of tubulin between monomer and polymer under conditions of dynamic instability. Cell Biophysics. 11: 35-55. PMID 2450668  0.59
1987 Mitchison TJ. Cell motility: good things from slime. Nature. 328: 665. PMID 2441263 DOI: 10.1038/328665A0  0.347
1986 Mitchison TJ, Kirschner MW. Isolation of mammalian centrosomes. Methods in Enzymology. 134: 261-8. PMID 3821566 DOI: 10.1016/0076-6879(86)34094-1  0.526
1986 Mitchison T, Evans L, Schulze E, Kirschner M. Sites of microtubule assembly and disassembly in the mitotic spindle. Cell. 45: 515-527. PMID 3708686 DOI: 10.1016/0092-8674(86)90283-7  0.685
1986 Kirschner M, Mitchison T. Beyond self-assembly: from microtubules to morphogenesis. Cell. 45: 329-42. PMID 3516413 DOI: 10.1016/0092-8674(86)90318-1  0.629
1986 Kristofferson D, Mitchison T, Kirschner M. Direct observation of steady-state microtubule dynamics. The Journal of Cell Biology. 102: 1007-19. PMID 3005332 DOI: 10.1083/Jcb.102.3.1007  0.66
1986 KRISTOFFERSON D, MITCHISON T, KIRSCHNER M. Direct Visualization of Steady State Microtubule Dynamics in Vitro Annals of the New York Academy of Sciences. 466: 664-665. DOI: 10.1111/J.1749-6632.1986.Tb38447.X  0.609
1985 Evans L, Mitchison T, Kirschner M. Influence of the centrosome on the structure of nucleated microtubules. The Journal of Cell Biology. 100: 1185-91. PMID 4038981 DOI: 10.1083/Jcb.100.4.1185  0.688
1985 Mitchison TJ, Kirschner MW. Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation. The Journal of Cell Biology. 101: 766-77. PMID 4030894 DOI: 10.1083/Jcb.101.3.766  0.686
1985 Mitchison TJ, Kirschner MW. Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding. The Journal of Cell Biology. 101: 755-65. PMID 4030893 DOI: 10.1083/Jcb.101.3.755  0.698
1985 Vale RD, Schnapp BJ, Mitchison T, Steuer E, Reese TS, Sheetz MP. Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell. 43: 623-32. PMID 2416467 DOI: 10.1016/0092-8674(85)90234-X  0.407
1984 Karsenti E, Kobayashi S, Mitchison T, Kirschner M. Role of the centrosome in organizing the interphase microtubule array: Properties of cytoplasts containing or lacking centrosomes Journal of Cell Biology. 98: 1763-1776. PMID 6725398 DOI: 10.1083/Jcb.98.5.1763  0.789
1984 Calarco-Gillam PD, Siebert MC, Hubble R, Mitchison T, Kirschner M. Centrosome development in early mouse embryos as defined by an autoantibody against pericentriolar material. Cell. 35: 621-9. PMID 6652679 DOI: 10.1016/0092-8674(83)90094-6  0.675
1984 Mitchison T, Kirschner M. Dynamic instability of microtubule growth. Nature. 312: 237-42. PMID 6504138 DOI: 10.1038/312237A0  0.673
1984 Mitchison T, Kirschner M. Microtubule assembly nucleated by isolated centrosomes. Nature. 312: 232-7. PMID 6504137 DOI: 10.1038/312232A0  0.718
1984 Leslie RJ, Saxton WM, Mitchison TJ, Neighbors B, Salmon ED, McIntosh JR. Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching Journal of Cell Biology. 99: 2146-2156. PMID 6438113 DOI: 10.1083/Jcb.99.6.2146  0.419
1983 Mitchison TJ, Sedat J. Localization of antigenic determinants in whole Drosophila embryos. Developmental Biology. 99: 261-4. PMID 6194030 DOI: 10.1016/0012-1606(83)90275-0  0.549
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