| Year |
Citation |
Score |
| 2018 |
Suen LM, Tekle-Smith MA, Williamson KS, Infantine JR, Reznik SK, Tanis PS, Casselman TD, Sackett DL, Leighton JL. Design and 22-step synthesis of highly potent D-ring modified and linker-equipped analogs of spongistatin 1. Nature Communications. 9: 4710. PMID 30413713 DOI: 10.1038/S41467-018-07259-X |
0.83 |
|
| 2017 |
Tekle-Smith MA, Williamson KS, Hughes IF, Leighton JL. Direct, Mild, and General n-Bu4NBr-Catalyzed Aldehyde Allylsilylation with Allyl Chlorides. Organic Letters. PMID 29068688 DOI: 10.1021/Acs.Orglett.7B03193 |
0.534 |
|
| 2017 |
Foley CN, Chen LA, Sackett DL, Leighton JL. Synthesis and Evaluation of a Linkable Functional Group-Equipped Analogue of the Epothilones. Acs Medicinal Chemistry Letters. 8: 701-704. PMID 28740601 DOI: 10.1021/Acsmedchemlett.7B00131 |
0.779 |
|
| 2017 |
Su TA, Li H, Klausen RS, Kim NT, Neupane M, Leighton JL, Steigerwald ML, Venkataraman L, Nuckolls C. Silane and Germane Molecular Electronics. Accounts of Chemical Research. PMID 28345881 DOI: 10.1021/Acs.Accounts.7B00059 |
0.66 |
|
| 2017 |
Chen LA, Ashley MA, Leighton JL. Evolution of an Efficient and Scalable Nine-Step (LLS) Synthesis of Zincophorin Methyl Ester. Journal of the American Chemical Society. PMID 28266852 DOI: 10.1021/Jacs.7B01590 |
0.498 |
|
| 2015 |
Foley CN, Leighton JL. A Highly Stereoselective, Efficient, and Scalable Synthesis of the C(1)-C(9) Fragment of the Epothilones. Organic Letters. PMID 26561788 DOI: 10.1021/Acs.Orglett.5B03034 |
0.814 |
|
| 2015 |
Ho S, Sackett DL, Leighton JL. A "Methyl Extension" Strategy for Polyketide Natural Product Linker Site Validation and Its Application to Dictyostatin. Journal of the American Chemical Society. 137: 14047-50. PMID 26522184 DOI: 10.1021/Jacs.5B09869 |
0.344 |
|
| 2015 |
Plummer CW, Wei CS, Yozwiak CE, Soheili A, Smithback SO, Leighton JL. Correction to "Design, Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core". Journal of the American Chemical Society. 137: 13722. PMID 26461137 DOI: 10.1021/Jacs.5B09617 |
0.828 |
|
| 2014 |
Plummer CW, Wei CS, Yozwiak CE, Soheili A, Smithback SO, Leighton JL. Design, development, mechanistic elucidation, and rational optimization of a tandem Ireland Claisen/Cope rearrangement reaction for rapid access to the (iso)cyclocitrinol core. Journal of the American Chemical Society. 136: 9878-81. PMID 24967720 DOI: 10.1021/ja505131v |
0.829 |
|
| 2014 |
Foley CN, Leighton JL. Beyond the roche ester: A new approach to polypropionate stereotriad synthesis Organic Letters. 16: 1180-1183. PMID 24502345 DOI: 10.1021/Ol500051E |
0.818 |
|
| 2013 |
Suen LM, Steigerwald ML, Leighton JL. A new and more powerfully activating diamine for practical and scalable enantioselective aldehyde crotylsilylation reactions. Chemical Science (Royal Society of Chemistry : 2010). 4: 2413-2417. PMID 25165504 DOI: 10.1039/C3Sc50714A |
0.473 |
|
| 2013 |
Reznik SK, Leighton JL. Toward a more step-economical and scalable synthesis of spongistatin 1 to facilitate cancer drug development efforts. Chemical Science (Royal Society of Chemistry : 2010). 4: 1497-1501. PMID 25165503 DOI: 10.1039/C3Sc22186E |
0.822 |
|
| 2013 |
Su TA, Widawsky JR, Li H, Klausen RS, Leighton JL, Steigerwald ML, Venkataraman L, Nuckolls C. Silicon ring strain creates high-conductance pathways in single-molecule circuits. Journal of the American Chemical Society. 135: 18331-4. PMID 24261548 DOI: 10.1021/Ja410656A |
0.771 |
|
| 2013 |
Tanis PS, Infantine JR, Leighton JL. Exploiting pseudo C 2-symmetry for an efficient synthesis of the F-ring of the spongistatins Organic Letters. 15: 5464-5467. PMID 24111885 DOI: 10.1021/Ol402604S |
0.447 |
|
| 2013 |
Ho S, Bucher C, Leighton JL. A highly step-economical synthesis of dictyostatin Angewandte Chemie - International Edition. 52: 6757-6761. PMID 23666786 DOI: 10.1002/Anie.201302565 |
0.453 |
|
| 2013 |
Suen LM, Steigerwald ML, Leighton JL. A new and more powerfully activating diamine for practical and scalable enantioselective aldehyde crotylsilylation reactions Chemical Science. 4: 2413-2417. DOI: 10.1039/c3sc50714a |
0.348 |
|
| 2013 |
Reznik SK, Leighton JL. Toward a more step-economical and scalable synthesis of spongistatin 1 to facilitate cancer drug development efforts Chemical Science. 4: 1497-1501. DOI: 10.1039/c3sc22186e |
0.787 |
|
| 2012 |
Reznik SK, Marcus BS, Leighton JL. Complex fragment coupling by crotylation: A powerful tool for polyketide natural product synthesis. Chemical Science (Royal Society of Chemistry : 2010). 3: 3326-3330. PMID 25165502 DOI: 10.1039/C2Sc21325G |
0.835 |
|
| 2012 |
Harrison TJ, Rabbat PMA, Leighton JL. An "aprotic" Tamao oxidation/syn-selective tautomerization reaction for the efficient synthesis of the C(1)-C(9) fragment of fludelone Organic Letters. 14: 4890-4893. PMID 22950417 DOI: 10.1021/Ol302221S |
0.331 |
|
| 2012 |
Chalifoux WA, Reznik SK, Leighton JL. Direct and highly regioselective and enantioselective allylation of β-diketones Nature. 486: 86-89. PMID 22763452 DOI: 10.1038/Nature11189 |
0.838 |
|
| 2012 |
Schönherr H, Leighton JL. Direct and highly enantioselective iso-Pictet-Spengler reactions with α-ketoamides: access to underexplored indole core structures. Organic Letters. 14: 2610-3. PMID 22540677 DOI: 10.1021/Ol300922B |
0.508 |
|
| 2012 |
Plummer CW, Soheili A, Leighton JL. A tandem cross-metathesis/semipinacol rearrangement reaction. Organic Letters. 14: 2462-4. PMID 22540517 DOI: 10.1021/Ol300691U |
0.825 |
|
| 2012 |
Reznik SK, Marcus BS, Leighton JL. Complex fragment coupling by crotylation: A powerful tool for polyketide natural product synthesis Chemical Science. 3: 3326-3330. DOI: 10.1039/c2sc21325g |
0.796 |
|
| 2012 |
Schönherr H, Leighton JL. Direct and highly enantioselective iso-Pictet-Spengler reactions with α-ketoamides: Access to underexplored indole core structures Organic Letters. 14: 2610-2613. DOI: 10.1021/ol300922b |
0.333 |
|
| 2011 |
Baxter Vu JM, Leighton JL. A new synthesis of pyrrolidines by way of an enantioselective Mannich/diastereoselective hydroamination reaction sequence Organic Letters. 13: 4056-4059. PMID 21749067 DOI: 10.1021/Ol201566U |
0.572 |
|
| 2011 |
Harrison TJ, Ho S, Leighton JL. Toward more "ideal" polyketide natural product synthesis: A step-economical synthesis of zincophorin methyl ester Journal of the American Chemical Society. 133: 7308-7311. PMID 21524078 DOI: 10.1021/Ja201467Z |
0.513 |
|
| 2011 |
Kim H, Ho S, Leighton JL. A more comprehensive and highly practical solution to enantioselective aldehyde crotylation Journal of the American Chemical Society. 133: 6517-6520. PMID 21486033 DOI: 10.1021/Ja200712F |
0.444 |
|
| 2011 |
Notte GT, Baxter Vu JM, Leighton JL. Highly enantioselective mannich reactions with α-aryl silyl ketene acetals and imines Organic Letters. 13: 816-818. PMID 21235253 DOI: 10.1021/Ol103096U |
0.551 |
|
| 2011 |
Kim H, Ho S, Leighton J. Highly Selective Scandium-Catalyzed Aldehyde Crotylation Synfacts. 2011: 875-875. DOI: 10.1055/S-0030-1260741 |
0.396 |
|
| 2010 |
Tambar UK, Lee SK, Leighton JL. Enantioselective (formal) aza-Diels-Alder reactions with non-Danishefsky-type dienes. Journal of the American Chemical Society. 132: 10248-50. PMID 20662502 DOI: 10.1021/Ja104480G |
0.849 |
|
| 2010 |
Olechowski CJ, Parmar A, Miller B, Stephan J, Tenorio G, Tran K, Leighton J, Kerr BJ. A diminished response to formalin stimulation reveals a role for the glutamate transporters in the altered pain sensitivity of mice with experimental autoimmune encephalomyelitis (EAE). Pain. 149: 565-72. PMID 20399559 DOI: 10.1016/J.Pain.2010.03.037 |
0.474 |
|
| 2010 |
Feske MI, Santanilla AB, Leighton JL. Asymmetric allylation, crotylation, and cinnamylation of N-heteroaryl hydrazones. Organic Letters. 12: 688-91. PMID 20085348 DOI: 10.1021/Ol9026864 |
0.809 |
|
| 2010 |
Leighton J, Tambar U, Lee S. Enantioselective Aza-Diels-Alder Reactions Synfacts. 2010: 1153-1153. DOI: 10.1055/s-0030-1258646 |
0.383 |
|
| 2010 |
Leighton J, Lee S, Tambar U, Perl N. Synthesis of Casopitant Synfacts. 2010: 0975-0975. DOI: 10.1055/S-0030-1257873 |
0.479 |
|
| 2010 |
Valdez SC, Leighton JL. Tandem Asymmetric Aza-Darzens/Ring-Opening Reactions Synfacts. 2010: 67-67. DOI: 10.1055/S-0029-1218513 |
0.471 |
|
| 2010 |
Feske MI, Santanilla AB, Leighton JL. Asymmetric allylation, crotylation, and cinnamylation of N-heteroaryl hydrazones Organic Letters. 12: 688-691. DOI: 10.1021/ol9026864 |
0.771 |
|
| 2010 |
Lee SK, Tambar UK, Perl NR, Leighton JL. Highly enantioselective formal aza-Diels-Alder reactions with acylhydrazones and Danishefsky's diene promoted by a silicon Lewis acid Tetrahedron. 66: 4769-4774. DOI: 10.1016/J.Tet.2010.03.036 |
0.844 |
|
| 2010 |
O'Malley SJ, Leighton JL. ChemInform Abstract: Tandem Intramolecular Alkyne Silylformylation-Allylsilylation: A Case of Remote 1,5-Asymmetric Induction. Cheminform. 32: no-no. DOI: 10.1002/chin.200147049 |
0.794 |
|
| 2010 |
LEIGHTON JL, CHAPMAN E. ChemInform Abstract: Rhodium-Catalyzed Intramolecular Silylformylation of Alkenes. Cheminform. 29: no-no. DOI: 10.1002/chin.199815049 |
0.428 |
|
| 2010 |
EVANS DA, BARROW JC, LEIGHTON JL, ROBICHAUD AJ, SEFKOW M. ChemInform Abstract: Asymmetric Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C. Cheminform. 26: no-no. DOI: 10.1002/chin.199522277 |
0.425 |
|
| 2010 |
EVANS DA, LEIGHTON JL, GAGE JR. ChemInform Abstract: The Asymmetric Synthesis of (+)-Calyculin A, a Nanomolar Phosphatase 1 and 2A Inhibitor Cheminform. 24: no-no. DOI: 10.1002/chin.199349301 |
0.37 |
|
| 2010 |
EVANS DA, GAGE JR, LEIGHTON JL. ChemInform Abstract: Total Synthesis of (+)-Calyculin A. Cheminform. 24: no-no. DOI: 10.1002/chin.199314299 |
0.499 |
|
| 2009 |
Valdez SC, Leighton JL. Tandem asymmetric Aza-Darzens/ring-opening reactions: dual functionality from the silane lewis acid. Journal of the American Chemical Society. 131: 14638-9. PMID 19778019 DOI: 10.1021/Ja9066354 |
0.77 |
|
| 2009 |
Bou-Hamdan FR, Leighton JL. Highly enantioselective pictet-spengler reactions with α-ketoamide- derived ketimines: Access to an unusual class of quaternary α-amino amides Angewandte Chemie - International Edition. 48: 2403-2406. PMID 19222080 DOI: 10.1002/Anie.200806110 |
0.433 |
|
| 2009 |
Leighton J, Spletstoser J, Zacuto M. Methodology for the Synthesis of Polyketide Fragments Synfacts. 2009: 0301-0301. DOI: 10.1055/S-0028-1087752 |
0.789 |
|
| 2009 |
Valdez SC, Leighton JL. Tandem asymmetric aza-Darzens/ring-opening reactions: Dual functionality from the silane Lewis acid Journal of the American Chemical Society. 131: 14638-14639. DOI: 10.1021/ja9066354 |
0.714 |
|
| 2008 |
Spletstoser JT, Zacuto MJ, Leighton JL. Tandem silylformylation - Crotylsilylation/tamao oxidation of internal alkynes: A remarkable example of generating complexity from simplicity Organic Letters. 10: 5593-5596. PMID 19007175 DOI: 10.1021/Ol802489W |
0.783 |
|
| 2008 |
Tran K, Lombardi PJ, Leighton JL. An efficient asymmetric synthesis of manzacidin C. Organic Letters. 10: 3165-7. PMID 18572947 DOI: 10.1021/Ol8011869 |
0.832 |
|
| 2008 |
Notte GT, Leighton JL. A new silicon lewis acid for highly enantioselective Mannich reactions of aliphatic ketone-derived hydrazones Journal of the American Chemical Society. 130: 6676-6677. PMID 18444641 DOI: 10.1021/Ja800830H |
0.488 |
|
| 2008 |
Huber JD, Perl NR, Leighton JL. Allylsilane-vinylarene cross-metathesis enables a powerful approach to enantioselective imine allylation Angewandte Chemie - International Edition. 47: 3037-3039. PMID 18338347 DOI: 10.1002/Anie.200705621 |
0.331 |
|
| 2008 |
Leighton J, Huber J, Perl N. Domino Stereoselective Cross-Metathesis-Imine Cinnamylation Synfacts. 2008: 0738-0738. DOI: 10.1055/S-2008-1078464 |
0.341 |
|
| 2007 |
Huber JD, Leighton JL. Highly enantioselective imine cinnamylation with a remarkable diastereochemical switch Journal of the American Chemical Society. 129: 14552-14553. PMID 17983233 DOI: 10.1021/Ja076035H |
0.408 |
|
| 2007 |
Perl NR, Leighton JL. Enantioselective imidazole-directed allylation of aldimines and ketimines Organic Letters. 9: 3699-3701. PMID 17685538 DOI: 10.1021/Ol701723W |
0.573 |
|
| 2007 |
Leighton J, Rabbat P, Valdez S. Enantioselective Allylation of Imines Directed by Phenols Synfacts. 2007: 0278-0278. DOI: 10.1055/S-2007-968276 |
0.82 |
|
| 2007 |
Castagner B, Leighton JL. A modified approach to the phomoidrides: synthesis of a late-stage intermediate containing a key carbon quaternary stereocenter Tetrahedron. 63: 5895-5902. DOI: 10.1016/J.Tet.2007.02.106 |
0.773 |
|
| 2006 |
Rabbat PMA, Valdez SC, Leighton JL. Phenol-directed enantioselective allylation of aldimines and ketimines Organic Letters. 8: 6119-6120. PMID 17165944 DOI: 10.1021/Ol062589Y |
0.752 |
|
| 2006 |
Burns NZ, Hackman BM, Ng PY, Powelson IA, Leighton JL. The enantioselective allylation and crotylation of sterically hindered and functionalized aryl ketones: convenient access to unusual tertiary carbinol structures. Angewandte Chemie (International Ed. in English). 45: 3811-3. PMID 16671141 DOI: 10.1002/Anie.200600910 |
0.797 |
|
| 2006 |
Park PK, O'Malley SJ, Schmidt DR, Leighton JL. Total synthesis of dolabelide D Journal of the American Chemical Society. 128: 2796-2797. PMID 16506747 DOI: 10.1021/Ja058692K |
0.809 |
|
| 2006 |
Leighton J, Park P, O’Malley S, Schmidt D. Synthesis of Dolabelide D Synfacts. 2006: 0747-0747. DOI: 10.1055/S-2006-941933 |
0.33 |
|
| 2006 |
Kubota K, Hamblett CL, Wang X, Leighton JL. Strained silacycle-catalyzed asymmetric Diels-Alder cycloadditions: the first highly enantioselective silicon Lewis acid catalyst Tetrahedron. 62: 11397-11401. DOI: 10.1016/J.Tet.2006.06.076 |
0.808 |
|
| 2006 |
Tran K, Leighton JL. A simple, efficient, and highly enantioselective synthesis of MS-153 employing a chiral silane Lewis acid-promoted acylhydrazone-enol ether [3+2] cycloaddition Advanced Synthesis and Catalysis. 348: 2431-2436. DOI: 10.1002/Adsc.200600357 |
0.696 |
|
| 2005 |
Zacuto MJ, Leighton JL. Divergent synthesis of complex polyketide-like macrolides from a simple polyol fragment Organic Letters. 7: 5525-5527. PMID 16288547 DOI: 10.1021/Ol052373G |
0.756 |
|
| 2005 |
Wang X, Meng Q, Perl NR, Xu Y, Leighton JL. Tandem aldol-allylation and aldol-aldol reactions with ketone-derived enolsilanes: Highly diastereoselective single-step synthesis of complex tertiary carbinols Journal of the American Chemical Society. 127: 12806-12807. PMID 16159267 DOI: 10.1021/Ja053593S |
0.83 |
|
| 2005 |
Bolshakov S, Leighton JL. Efficient asymmetric synthesis of (+)-SCH 351448 Organic Letters. 7: 3809-3812. PMID 16092881 DOI: 10.1021/Ol0515006 |
0.783 |
|
| 2005 |
Shirakawa S, Lombardi PJ, Leighton JL. A simple and general chiral silicon Lewis acid for asymmetric synthesis: highly enantioselective [3+2] acylhydrazone-enol ether cycloadditions. Journal of the American Chemical Society. 127: 9974-5. PMID 16011341 DOI: 10.1021/Ja052307+ |
0.853 |
|
| 2005 |
Shirakawa S, Berger R, Leighton JL. Enantioselective friedel-crafts alkylations with benzoylhydrazones promoted by a simple strained silacycle reagent. Journal of the American Chemical Society. 127: 2858-9. PMID 15740114 DOI: 10.1021/Ja042522A |
0.763 |
|
| 2005 |
Leighton J, Bolshakov S. Synthesis of (+)-SCH 351338 Synfacts. 2006: 0013-0013. DOI: 10.1055/s-2005-921664 |
0.732 |
|
| 2005 |
Shirakawa S, Berger R, Leighton JL. Enantioselective Friedel-Crafts Alkylations by Strained Chiral Silacycle Synfacts. 2005: 48-48. DOI: 10.1055/S-2005-869914 |
0.63 |
|
| 2005 |
Shirakawa S, Lombardi PJ, Leighton JL. A simple and general chiral silicon Lewis acid for asymmetric synthesis: Highly enantioselective [3 + 2] acylhydrazone-enol ether cycloadditions Journal of the American Chemical Society. 127: 9974-9975. DOI: 10.1021/ja052307+ |
0.838 |
|
| 2005 |
Shirakawa S, Berger R, Leighton JL. Enantioselective friedel-crafts alkylations with benzoylhydrazones promoted by a simple strained silacycle reagent Journal of the American Chemical Society. 127: 2858-2859. DOI: 10.1021/ja042522a |
0.664 |
|
| 2005 |
Leighton JL. Stereoselective Rhodium(I)-Catalyzed Hydroformylation and Silylformylation Reactions and Their Application to Organic Synthesis Modern Rhodium-Catalyzed Organic Reactions. 93-110. DOI: 10.1002/3527604693.ch5 |
0.414 |
|
| 2004 |
Hackman BM, Lombardi PJ, Leighton JL. Highly diastereo- and enantioselective reagents for aldehyde crotylation Organic Letters. 6: 4375-4377. PMID 15524487 DOI: 10.1021/Ol0480731 |
0.812 |
|
| 2004 |
Duncan AP, Leighton JL. Enantioselective Cu-catalyzed conjugate addition of diethylzinc to acyclic aliphatic enones Organic Letters. 6: 4117-4119. PMID 15496113 DOI: 10.1021/Ol048191O |
0.441 |
|
| 2004 |
Berger R, Duff K, Leighton JL. Enantioselective allylation of ketone-derived benzoylhydrazones: practical synthesis of tertiary carbinamines. Journal of the American Chemical Society. 126: 5686-7. PMID 15125659 DOI: 10.1021/Ja0486418 |
0.653 |
|
| 2003 |
Schmidt DR, Park PK, Leighton JL. Approach to the Synthesis of Dolabelides A and B: Fragment Synthesis by Tandem Silylformylation-Crotylsilylation Organic Letters. 5: 3535-3537. PMID 12967318 DOI: 10.1021/Ol035431B |
0.424 |
|
| 2003 |
Krauss IJ, Leighton JL. Highly practical and enantioselective cu-catalyzed conjugate addition of alkylzinc reagents to cyclic enones at ambient temperature. Organic Letters. 5: 3201-3. PMID 12943387 DOI: 10.1021/Ol034983R |
0.749 |
|
| 2003 |
Berger R, Rabbat PMA, Leighton JL. Toward a versatile allylation reagent: Practical, enantioselective allylation of acylhydrazones using strained silacycles Journal of the American Chemical Society. 125: 9596-9597. PMID 12904019 DOI: 10.1021/Ja035001G |
0.585 |
|
| 2003 |
Bio MM, Leighton JL. An approach to the synthesis of the phomoidrides Journal of Organic Chemistry. 68: 1693-1700. PMID 12608780 DOI: 10.1021/Jo026478Y |
0.766 |
|
| 2003 |
Kubota K, Leighton JL. A highly practical and enantioselective reagent for the allylation of aldehydes. Angewandte Chemie (International Ed. in English). 42: 946-8. PMID 12596186 DOI: 10.1002/Anie.200390252 |
0.456 |
|
| 2003 |
Schmidt DR, O'Malley SJ, Leighton JL. Catalytic asymmetric silane alcoholysis: Practical access to chiral silanes Journal of the American Chemical Society. 125: 1190-1191. PMID 12553820 DOI: 10.1021/Ja0283201 |
0.837 |
|
| 2003 |
Krauss IJ, Leighton JL. Highly practical and enantioselective Cu-catalyzed conjugate addition of alkylzinc reagents to cyclic enones at ambient temperature Organic Letters. 5: 3201-3203. DOI: 10.1021/ol034983r |
0.689 |
|
| 2003 |
Zacuto MJ, O'Malley SJ, Leighton JL. Tandem silylformylation-allyl(crotyl)silylation: A new approach to polyketide synthesis Tetrahedron. 59: 8889-8900. DOI: 10.1016/J.Tet.2003.04.004 |
0.848 |
|
| 2003 |
Kubota K, Leighton JL. A highly practical and enantioselective reagent for the allylation of aldehydes Angewandte Chemie - International Edition. 42: 946-948. DOI: 10.1002/anie.200390252 |
0.349 |
|
| 2002 |
Wang X, Meng Q, Nation AJ, Leighton JL. Strained silacycles in organic synthesis: The tandem aidol-allylation reaction Journal of the American Chemical Society. 124: 10672-10673. PMID 12207519 DOI: 10.1021/Ja027655F |
0.791 |
|
| 2002 |
Kinnaird JWA, Ng PY, Kubota K, Wang X, Leighton JL. Strained silacycles in organic synthesis: A new reagent for the enantioselective allylation of aldehydes Journal of the American Chemical Society. 124: 7920-7921. PMID 12095334 DOI: 10.1021/Ja0264908 |
0.829 |
|
| 2002 |
Zacuto MJ, O'Malley SJ, Leighton JL. Tandem intramolecular silylformylation-crotylsilylation: Highly efficient synthesis of polyketide fragments Journal of the American Chemical Society. 124: 7890-7891. PMID 12095319 DOI: 10.1021/Ja026511Y |
0.837 |
|
| 2001 |
O'Malley SJ, Leighton JL. Tandem Intramolecular Alkyne Silylformylation-Allylsilylation: A Case of Remote 1,5-Asymmetric Induction. Angewandte Chemie (International Ed. in English). 40: 2915-2917. PMID 29711987 DOI: 10.1002/1521-3773(20010803)40:15<2915::Aid-Anie2915>3.0.Co;2-9 |
0.832 |
|
| 2001 |
Krauss IJ, Wang CCY, Leighton JL. Highly regioselective and diastereoselective directed hydroformylation of allylic ethers: A new approach to propionate aldol synthesis [10] Journal of the American Chemical Society. 123: 11514-11515. PMID 11707144 DOI: 10.1021/Ja016978T |
0.782 |
|
| 2001 |
O'Malley SJ, Leighton JL. Tandem Intramolecular Alkyne Silylformylation-Allylsilylation: A Case of Remote 1,5-Asymmetric Induction Financial support was provided by the National Institutes of Health (National Institute of General Medical Sciences, GM58133). We are grateful to Bristol-Myers Squibb for generous financial support in the form of an Unrestricted Grant in Synthetic Organic Chemistry to J.L.L. We thank Merck Research Laboratories and DuPont Pharmaceuticals for generous financial support. Angewandte Chemie (International Ed. in English). 40: 2915-2917. PMID 11500908 DOI: 10.1002/1521-3773(20010803)40:15<2915::AID-ANIE2915>3.0.CO;2-9 |
0.749 |
|
| 2001 |
Dreher SD, Leighton JL. Formal total synthesis of mycoticin A [6] Journal of the American Chemical Society. 123: 341-342. PMID 11456525 DOI: 10.1021/Ja0035102 |
0.46 |
|
| 2001 |
Dreher SD, Leighton JL. ChemInform Abstract: Formal Total Synthesis of Mycoticin A. Cheminform. 32: no-no. DOI: 10.1002/chin.200116228 |
0.347 |
|
| 2001 |
O'Malley SJ, Leighton JL. Tandem intramolecular alkyne silylformylation-allylsilylation: A case of remote 1,5-asymmetric induction Angewandte Chemie - International Edition. 40: 2915-2917. DOI: 10.1002/1521-3773(20010803)40:15<2915::AID-ANIE2915>3.0.CO;2-9 |
0.79 |
|
| 2000 |
Sarraf ST, Leighton JL. Rhodium-catalyzed formylation of organomercurials: Application to efficient polyol synthesis Organic Letters. 2: 3205-3208. PMID 11009382 DOI: 10.1021/Ol006393O |
0.856 |
|
| 2000 |
Dreher SD, Hornberger KR, Sarraf ST, Leighton JL. Yb(OTf)3-catalyzed oxymercuration of homoallylic alcohol-derived hemiacetals and hemiketals Organic Letters. 2: 3197-3199. PMID 11009380 DOI: 10.1021/Ol0063860 |
0.804 |
|
| 2000 |
Bio MM, Leighton JL. Stereoconvergent palladium-catalyzed carbonylation of both E and Z isomers of a 2-trifloxy-1,3-butadiene. Organic Letters. 2: 2905-7. PMID 10964395 DOI: 10.1021/Ol0063609 |
0.76 |
|
| 2000 |
Sarraf ST, Leighton JL. Oxymercuration of homoallylic alcohol derived hemiacetals: Diastereoselective synthesis of protected 1,3-diols Organic Letters. 2: 403-405. PMID 10814334 DOI: 10.1021/Ol991370Z |
0.836 |
|
| 2000 |
Hornberger KR, Hamblett CL, Leighton JL. Total synthesis of leucascandrolide A [16] Journal of the American Chemical Society. 122: 12894-12895. DOI: 10.1021/Ja003593M |
0.814 |
|
| 2000 |
Zacuto MJ, Leighton JL. Tandem intramolecular silylformylation-allylsilylation [15] Journal of the American Chemical Society. 122: 8587-8588. DOI: 10.1021/Ja002425R |
0.774 |
|
| 2000 |
Zacuto MJ, Leighton JL. ChemInform Abstract: Tandem Intramolecular Silylformylation-Allylsilylation. Cheminform. 31: no-no. DOI: 10.1002/chin.200049085 |
0.744 |
|
| 2000 |
Bio MM, Leighton JL. Stereoconvergent palladium-catalyzed carbonylation of both E and Z isomers of a 2-trifloxy-1,3-butadiene Organic Letters. 2: 2905-2907. |
0.681 |
|
| 1999 |
Bio MM, Leighton JL. An approach to the synthesis of CP-263,114: A remarkably facile silyloxy-Cope rearrangement [18] Journal of the American Chemical Society. 121: 890-891. DOI: 10.1021/Ja983609X |
0.729 |
|
| 1998 |
Sarraf ST, Leighton JL. Unusual conformational effects on the regioselectivity of olefin insertion in the rhodium-catalyzed hydroformylation of 4-methylene-1,3- dioxanes Tetrahedron Letters. 39: 6423-6426. DOI: 10.1016/S0040-4039(98)01351-3 |
0.832 |
|
| 1997 |
Leighton JL, Chapman E. Rhodium-Catalyzed Intramolecular Silylformylation of Alkenes Journal of the American Chemical Society. 119: 12416-12417. DOI: 10.1021/Ja973095M |
0.56 |
|
| 1997 |
Leighton JL, O'Neil DN. Highly diastereoselective rhodium-catalyzed hydroformylation of enol ethers: A carbonylation-based approach to catalytic aldol synthesis Journal of the American Chemical Society. 119: 11118-11119. DOI: 10.1021/Ja972121D |
0.54 |
|
| 1996 |
Leighton JL, Jacobsen EN. Efficient synthesis of (R)-4-(trimethylsilyl)oxy)-2-cyclopentenone by enantioselective catalytic epoxide ring opening Journal of Organic Chemistry. 61: 389-390. DOI: 10.1021/Jo951557D |
0.604 |
|
| 1996 |
Hansen KB, Leighton JL, Jacobsen EN. On the mechanism of asymmetric nucleophilic ring-opening of epoxides catalyzed by (salen)Cr(III) complexes Journal of the American Chemical Society. 118: 10924-10925. DOI: 10.1021/Ja962600X |
0.613 |
|
| 1995 |
Martínez LE, Leighton JL, Carsten DH, Jacobsen EN. Highly enantioselective ring opening of epoxides catalyzed by (salen)Cr(III) complexes Journal of the American Chemical Society. 117: 5897-5898. DOI: 10.1021/Ja00126A048 |
0.546 |
|
| 1994 |
Evans DA, Barrow JC, Leighton JL, Robichaud AJ, Sefkow M. Asymmetric synthesis of the squalene synthase inhibitor zaragozic acid C Journal of the American Chemical Society. 116: 12111-12112. DOI: 10.1021/Ja00105A085 |
0.501 |
|
| 1992 |
Evans DA, Gage JR, Leighton JL. Asymmetric synthesis of calyculin A. 3. Assemblage of the calyculin skeleton and the introduction of a new phosphate monoester synthesis Journal of Organic Chemistry. 57: 1964-1966. DOI: 10.1021/Jo00033A011 |
0.527 |
|
| 1992 |
Evans DA, Gage JR, Leighton JL, Kim AS. Asymmetric synthesis of calyculin A. 2. The C26-C37 .gamma.-amino acid fragments The Journal of Organic Chemistry. 57: 1961-1963. DOI: 10.1021/Jo00033A010 |
0.521 |
|
| 1992 |
Evans DA, Gage JR, Leighton JL. Total synthesis of (+)-calyculin A Journal of the American Chemical Society. 114: 9434-9453. DOI: 10.1021/Ja00050A024 |
0.583 |
|
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