Robert C. Smart - Publications

Affiliations: 
North Carolina State University, Raleigh, NC 
Area:
Toxicology, Neuroscience Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 House JS, Gray S, Owen JR, Jima DD, Smart RC, Hall JR. C/EBPβ deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors. Innate Immunity. 17534259231162192. PMID 37094088 DOI: 10.1177/17534259231162192  0.373
2019 Tam HW, Hall JR, Messenger ZJ, Jima DD, House JS, Linder K, Smart RC. C/EBPβ Suppresses Keratinocyte Autonomous Type 1 IFN Response and p53 to Increase Cell Survival and Susceptibility to UVB-induced Skin Cancer. Carcinogenesis. PMID 30698678 DOI: 10.1093/Carcin/Bgz012  0.557
2018 Messenger ZJ, Hall JR, Jima DD, House JS, Tam HW, Tokarz DA, Smart RC. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death & Disease. 9: 1054. PMID 30323292 DOI: 10.1038/S41419-018-1103-Y  0.584
2015 Hall JR, Messenger ZJ, Tam HW, Phillips SL, Recio L, Smart RC. Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes. Cell Death & Disease. 6: e1700. PMID 25789975 DOI: 10.1038/Cddis.2015.67  0.405
2014 Hall JR, Bereman MS, Nepomuceno AI, Thompson EA, Muddiman DC, Smart RC. C/EBPα regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint. Cell Cycle (Georgetown, Tex.). 13: 3602-10. PMID 25483090 DOI: 10.4161/15384101.2014.962957  0.586
2011 Gaddameedhi S, Selby CP, Kaufmann WK, Smart RC, Sancar A. Control of skin cancer by the circadian rhythm. Proceedings of the National Academy of Sciences of the United States of America. 108: 18790-5. PMID 22025708 DOI: 10.1073/Pnas.1115249108  0.368
2011 Ming M, Feng L, Shea CR, Soltani K, Zhao B, Han W, Smart RC, Trempus CS, He YY. PTEN positively regulates UVB-induced DNA damage repair. Cancer Research. 71: 5287-95. PMID 21771908 DOI: 10.1158/0008-5472.Can-10-4614  0.414
2011 Deterding LJ, Williams JG, Humble MM, Petrovich RM, Wei SJ, Trempus CS, Gates MB, Zhu F, Smart RC, Tennant RW, Tomer KB. CD34 Antigen: Determination of Specific Sites of Phosphorylation In Vitro and In Vivo. International Journal of Mass Spectrometry. 301: 12-21. PMID 21499536 DOI: 10.1016/J.Ijms.2010.05.027  0.309
2011 Thompson EA, Zhu S, Hall JR, House JS, Ranjan R, Burr JA, He YY, Owens DM, Smart RC. C/EBPα expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPα confers susceptibility to UVB-induced skin squamous cell carcinomas. The Journal of Investigative Dermatology. 131: 1339-46. PMID 21346772 DOI: 10.1038/Jid.2011.31  0.623
2010 Omori E, Matsumoto K, Zhu S, Smart RC, Ninomiya-Tsuji J. Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells. Cancer Research. 70: 8417-25. PMID 20959492 DOI: 10.1158/0008-5472.Can-10-1227  0.428
2010 Kim TH, Chiera SL, Linder KE, Trempus CS, Smart RC, Horowitz JM. Overexpression of transcription factor Sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis Cancer Research. 70: 8507-8516. PMID 20959487 DOI: 10.1158/0008-5472.Can-10-1213  0.42
2010 House JS, Zhu S, Ranjan R, Linder K, Smart RC. C/EBPalpha and C/EBPbeta are required for Sebocyte differentiation and stratified squamous differentiation in adult mouse skin. Plos One. 5: e9837. PMID 20352127 DOI: 10.1371/Journal.Pone.0009837  0.597
2010 Lee S, Shuman JD, Guszczynski T, Sakchaisri K, Sebastian T, Copeland TD, Miller M, Cohen MS, Taunton J, Smart RC, Xiao Z, Yu LR, Veenstra TD, Johnson PF. RSK-mediated phosphorylation in the C/EBP{beta} leucine zipper regulates DNA binding, dimerization, and growth arrest activity. Molecular and Cellular Biology. 30: 2621-35. PMID 20351173 DOI: 10.1128/Mcb.00782-09  0.565
2010 Hall JR, Thompson EA, Smart RC. Abstract 3872: The role and regulation of C/EBPalpha in the DNA damage-induced G1checkpoint Cancer Research. 70: 3872-3872. DOI: 10.1158/1538-7445.Am10-3872  0.503
2009 Ranjan R, Thompson EA, Yoon K, Smart RC. C/EBPalpha expression is partially regulated by C/EBPbeta in response to DNA damage and C/EBPalpha-deficient fibroblasts display an impaired G1 checkpoint. Oncogene. 28: 3235-45. PMID 19581927 DOI: 10.1038/Onc.2009.176  0.773
2008 Ewing SJ, Zhu S, Zhu F, House JS, Smart RC. C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf). Cell Death and Differentiation. 15: 1734-44. PMID 18636078 DOI: 10.1038/Cdd.2008.105  0.804
2007 Loomis KD, Zhu S, Yoon K, Johnson PF, Smart RC. Genetic ablation of CCAAT/enhancer binding protein alpha in epidermis reveals its role in suppression of epithelial tumorigenesis. Cancer Research. 67: 6768-76. PMID 17638888 DOI: 10.1158/0008-5472.Can-07-0139  0.638
2007 Yoon K, Zhu S, Ewing SJ, Smart RC. Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function. Oncogene. 26: 360-7. PMID 16832342 DOI: 10.1038/Sj.Onc.1209797  0.796
2006 Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart RC, Ninomiya-Tsuji J. TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. The Journal of Biological Chemistry. 281: 19610-7. PMID 16675448 DOI: 10.1074/Jbc.M603384200  0.406
2006 Sterneck E, Zhu S, Ramirez A, Jorcano JL, Smart RC. Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis. Oncogene. 25: 1272-1276. PMID 16205634 DOI: 10.1038/Sj.Onc.1209144  0.534
2005 Shim M, Powers KL, Ewing SJ, Zhu S, Smart RC. Diminished expression of C/EBPalpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBPalpha in carcinoma cells inhibits proliferation. Cancer Research. 65: 861-7. PMID 15705884  0.799
2004 Yoon K, Smart RC. C/EBPalpha is a DNA damage-inducible p53-regulated mediator of the G1 checkpoint in keratinocytes. Molecular and Cellular Biology. 24: 10650-60. PMID 15572670 DOI: 10.1128/Mcb.24.24.10650-10660.2004  0.774
2004 Shuman JD, Sebastian T, Kaldis P, Copeland TD, Zhu S, Smart RC, Johnson PF. Cell cycle-dependent phosphorylation of C/EBPbeta mediates oncogenic cooperativity between C/EBPbeta and H-RasV12. Molecular and Cellular Biology. 24: 7380-91. PMID 15314150 DOI: 10.1128/Mcb.24.17.7380-7391.2004  0.53
2003 Shim M, Smart RC. Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBPalpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity. The Journal of Biological Chemistry. 278: 19674-81. PMID 12668682 DOI: 10.1074/Jbc.M301356200  0.803
2002 Porter KL, Chanda S, Wang HQ, Gaido KW, Smart RC, Robinette CL. 17beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 69: 42-8. PMID 12215659 DOI: 10.1093/Toxsci/69.1.42  0.385
2002 Tiano HF, Loftin CD, Akunda J, Lee CA, Spalding J, Sessoms A, Dunson DB, Rogan EG, Morham SG, Smart RC, Langenbach R. Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis. Cancer Research. 62: 3395-401. PMID 12067981  0.338
2002 Zhu S, Yoon K, Sterneck E, Johnson PF, Smart RC. CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 207-12. PMID 11756662 DOI: 10.1073/Pnas.012437299  0.804
2001 Wang HQ, Kim MP, Tiano HF, Langenbach R, Smart RC. Protein kinase C-alpha coordinately regulates cytosolic phospholipase A(2) activity and the expression of cyclooxygenase-2 through different mechanisms in mouse keratinocytes. Molecular Pharmacology. 59: 860-6. PMID 11259631 DOI: 10.1124/Mol.59.4.860  0.466
2000 Smart RC, Oh HS, Chanda S, Robinette CL. Effects of 17-beta-estradiol and ICI 182 780 on hair growth in various strains of mice. The Journal of Investigative Dermatology. Symposium Proceedings. 4: 285-9. PMID 10674383 DOI: 10.1038/Sj.Jidsp.5640231  0.345
2000 Chanda S, Robinette CL, Couse JF, Smart RC. 17beta-estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-alpha pathway. American Journal of Physiology. Endocrinology and Metabolism. 278: E202-10. PMID 10662703 DOI: 10.1152/Ajpendo.2000.278.2.E202  0.7
1999 Zhu S, Oh HS, Shim M, Sterneck E, Johnson PF, Smart RC. C/EBPbeta modulates the early events of keratinocyte differentiation involving growth arrest and keratin 1 and keratin 10 expression. Molecular and Cellular Biology. 19: 7181-90. PMID 10490653 DOI: 10.1128/Mcb.19.10.7181  0.771
1999 Owens DM, Wei S, Smart RC. A multihit, multistage model of chemical carcinogenesis. Carcinogenesis. 20: 1837-44. PMID 10469632 DOI: 10.1093/Carcin/20.9.1837  0.307
1999 Matsuura H, Adachi H, Smart RC, Xu X, Arata J, Jetten AM. Correlation between expression of peroxisome proliferator-activated receptor beta and squamous differentiation in epidermal and tracheobronchial epithelial cells. Molecular and Cellular Endocrinology. 147: 85-92. PMID 10195695 DOI: 10.1016/S0303-7207(98)00214-7  0.369
1998 Oh HS, Smart RC. Expression of CCAAT/enhancer binding proteins (C/EBP) is associated with squamous differentiation in epidermis and isolated primary keratinocytes and is altered in skin neoplasms. The Journal of Investigative Dermatology. 110: 939-45. PMID 9620302 DOI: 10.1046/J.1523-1747.1998.00199.X  0.613
1997 Kim TW, Porter KL, Foley JF, Maronpot RR, Smart RC. Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha-ras genotype. Molecular Carcinogenesis. 20: 115-24. PMID 9328442 DOI: 10.1002/(Sici)1098-2744(199709)20:1<115::Aid-Mc13>3.0.Co;2-4  0.469
1996 Oh HS, Smart RC. An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 93: 12525-30. PMID 8901615 DOI: 10.1073/Pnas.93.22.12525  0.364
1996 Goodell AL, Oh HS, Meyer SA, Smart RC. Epidermal protein kinase C-beta 2 is highly sensitive to downregulation and is exclusively expressed in Langerhans cells: downregulation is associated with attenuated contact hypersensitivity. The Journal of Investigative Dermatology. 107: 354-9. PMID 8751970 DOI: 10.1111/1523-1747.Ep12363325  0.345
1996 Owens DM, Zainal TA, Jetten AM, Smart RC. Localization and expression of cornifin-alpha/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasms. The Journal of Investigative Dermatology. 106: 647-54. PMID 8617999 DOI: 10.1111/1523-1747.Ep12345463  0.367
1995 Kim TW, Smart RC. Lack of effect of retinoic acid and fluocinolone acetonide on mirex tumor promotion indicates a novel mirex mechanism Carcinogenesis. 16: 2199-2204. PMID 7554075 DOI: 10.1093/Carcin/16.9.2199  0.429
1994 Meyer SA, Kim TW, Moser GJ, Monteiro-Riviere NA, Smart RC. Synergistic interaction between the non-phorbol ester-type promoter mirex and 12-O-tetradecanoylphorbol-13-acetate in mouse skin tumor promotion. Carcinogenesis. 15: 47-52. PMID 8293547 DOI: 10.1093/Carcin/15.1.47  0.46
1993 Moser GJ, Robinette CL, Smart RC. Characterization of skin tumor promotion by mirex: structure-activity relationships, sexual dimorphism and presence of Ha-ras mutation. Carcinogenesis. 14: 1155-60. PMID 8508502 DOI: 10.1093/Carcin/14.6.1155  0.452
1993 Mills KJ, Reynolds SH, Smart RC. Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes. Carcinogenesis. 14: 2645-8. PMID 8269640 DOI: 10.1093/Carcin/14.12.2645  0.444
1993 Colapietro AM, Goodell AL, Smart RC. Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels. Carcinogenesis. 14: 2289-95. PMID 8242857 DOI: 10.1093/Carcin/14.11.2289  0.485
1993 Meyer SA, Moser GJ, Monteiro-Riviere NA, Smart RC. Minimal role of enhanced cell proliferation in skin tumor promotion by mirex: a nonphorbol ester-type promoter. Environmental Health Perspectives. 101: 265-9. PMID 8013418 DOI: 10.1289/Ehp.93101S5265  0.457
1992 Mills KJ, Bocckino SB, Burns DJ, Loomis CR, Smart RC. Alterations in protein kinase c isozymes α and β in activated ha-ras containing papillomas in the absence of an increase in diacyiglycerol Carcinogenesis. 13: 1113-1120. PMID 1638676 DOI: 10.1093/Carcin/13.7.1113  0.41
1991 Smart RC, Crawford CL. Effect of ascorbic acid and its synthetic lipophilic derivative ascorbyl palmitate on phorbol ester-induced skin-tumor promotion in mice. The American Journal of Clinical Nutrition. 54: 1266S-1273S. PMID 1962581 DOI: 10.1093/Ajcn/54.6.1266S  0.416
1989 Moser GJ, Smart RC. Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity. Carcinogenesis. 10: 851-6. PMID 2706741 DOI: 10.1093/Carcin/10.5.851  0.351
1989 Mills KJ, Smart RC. Comparison of epidermal protein kinase c activity, ornithine decarboxylase induction and dna synthesis stimulated by tpa or dioctanoylglycerol in mouse strains with differing susceptibility to tpa–induced tumor promotion Carcinogenesis. 10: 833-838. PMID 2706740 DOI: 10.1093/Carcin/10.5.833  0.384
1988 Smart RC, Huang MT, Monteiro-riviere NA, Wong CQ, Mills KJ, Conney AH. Comparison of the effect of sn-1,2-didecanoylglycerol and 12-O-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD-1 mice Carcinogenesis. 9: 2221-2226. PMID 3191568 DOI: 10.1093/Carcin/9.12.2221  0.428
1986 Smart RC, Huang MT, Chang RL, Sayer JM, Jerina DM, Wood AW, Conney AH. Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice. Carcinogenesis. 7: 1669-75. PMID 3757169 DOI: 10.1093/Carcin/7.10.1669  0.341
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