Susan E. Leeman, PhD - Publications

Affiliations: 
Pharmacology Boston University School of Medicine, Boston, MA 
Area:
Neuroscience
Website:
http://www.bumc.bu.edu/busm-pm/faculty/faculty-profiles/leeman/

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Douglas SD, Leeman SE. Is substance P a nasal epithelial neuropeptide? The Journal of Allergy and Clinical Immunology. PMID 29958676 DOI: 10.1016/J.Jaci.2018.05.034  0.313
2017 Taracanova A, Alevizos M, Karagkouni A, Weng Z, Norwitz E, Conti P, Leeman SE, Theoharides TC. SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28461492 DOI: 10.1073/Pnas.1524845114  0.396
2016 Patel AB, Tsilioni I, Leeman SE, Theoharides TC. Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism. Proceedings of the National Academy of Sciences of the United States of America. PMID 27663735 DOI: 10.1073/Pnas.1604992113  0.361
2013 Yuan H, Zelkha S, Zelka S, Burkatovskaya M, Gupte R, Leeman SE, Amar S. Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss. Proceedings of the National Academy of Sciences of the United States of America. 110: E5059-68. PMID 24324141 DOI: 10.1073/Pnas.1320862110  0.311
2013 Burke RM, Norman TA, Haydar TF, Slack BE, Leeman SE, Blusztajn JK, Mellott TJ. BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 19567-72. PMID 24218590 DOI: 10.1073/Pnas.1319297110  0.602
2013 Bhargava A, Clifton MS, Mhaske P, Mhsake P, Liao M, Pothoulakis C, Leeman SE, Grady EF. Local injection of dsRNA targeting calcitonin receptor-like receptor (CLR) ameliorates Clostridium difficile toxin A-induced ileitis. Proceedings of the National Academy of Sciences of the United States of America. 110: 731-6. PMID 23267070 DOI: 10.1073/Pnas.1219733110  0.375
2013 Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF. Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer. Journal of Crohn's & Colitis. 7: 403-11. PMID 22921465 DOI: 10.1016/J.Crohns.2012.08.003  0.575
2011 Bushell KN, Leeman SE, Gillespie E, Gower AC, Reed KL, Stucchi AF, Becker JM, Amar S. LITAF mediation of increased TNF-α secretion from inflamed colonic lamina propria macrophages. Plos One. 6: e25849. PMID 21984950 DOI: 10.1371/Journal.Pone.0025849  0.752
2011 Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF, Becker JM. Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 17420-5. PMID 21969570 DOI: 10.1073/Pnas.1114275108  0.605
2011 Meshki J, Douglas SD, Hu M, Leeman SE, Tuluc F. Substance P induces rapid and transient membrane blebbing in U373MG cells in a p21-activated kinase-dependent manner. Plos One. 6: e25332. PMID 21966499 DOI: 10.1371/Journal.Pone.0025332  0.348
2011 Karagiannides I, Stavrakis D, Bakirtzi K, Kokkotou E, Pirtskhalava T, Nayeb-Hashemi H, Bowe C, Bugni JM, Nuño M, Lu B, Gerard NP, Leeman SE, Kirkland JL, Pothoulakis C. Substance P (SP)-neurokinin-1 receptor (NK-1R) alters adipose tissue responses to high-fat diet and insulin action. Endocrinology. 152: 2197-205. PMID 21467195 DOI: 10.1210/En.2010-1345  0.332
2011 Douglas SD, Leeman SE. Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation. Annals of the New York Academy of Sciences. 1217: 83-95. PMID 21091716 DOI: 10.1111/J.1749-6632.2010.05826.X  0.388
2010 Theoharides TC, Zhang B, Kempuraj D, Tagen M, Vasiadi M, Angelidou A, Alysandratos KD, Kalogeromitros D, Asadi S, Stavrianeas N, Peterson E, Leeman S, Conti P. IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin. Proceedings of the National Academy of Sciences of the United States of America. 107: 4448-53. PMID 20160089 DOI: 10.1073/Pnas.1000803107  0.34
2010 Gillespie E, Hetzel JT, Coukos J, Farraye FA, Cerda SR, O'Brien MJ, Leeman SE, Stucchi AF, Becker JM. M1951 Gene Expression of the Truncated Neurokinin-1 Receptor as Well as Two NF-kB Subunits is Altered in the Transition of Colonic Epithelial Cells From Quiescent Colitis to High Grade Dysplasia to Carcinoma in Colitis Associated Colorectal Cancer Gastroenterology. 138: S-446. DOI: 10.1016/S0016-5085(10)62061-6  0.585
2010 Gainsbury ML, Abdou R, Chu DI, Gillespie E, Heydrik S, Reed KL, Leeman SE, Stucchi AF, Becker JM. Hypoxia causes upregulation of the Neurokinin-1 Receptor (NK-1R) in rat peritoneal mesothelial cells (RPMCs): A necessary event in intraabdominal adhesion formation Journal of the American College of Surgeons. 211: S14-S15. DOI: 10.1016/J.Jamcollsurg.2010.06.032  0.622
2009 Zhou Q, Leeman SE, Amar S. Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses. Proceedings of the National Academy of Sciences of the United States of America. 106: 10740-5. PMID 19541650 DOI: 10.1073/Pnas.0904412106  0.304
2008 Reed KL, Stucchi AF, Leeman SE, Becker JM. Inhibitory effects of a neurokinin-1 receptor antagonist on postoperative peritoneal adhesion formation. Annals of the New York Academy of Sciences. 1144: 116-26. PMID 19076371 DOI: 10.1196/Annals.1418.010  0.333
2008 Ohtsuka N, Tansky MF, Kuang H, Kourrich S, Thomas MJ, Rubenstein JL, Ekker M, Leeman SE, Tsien JZ. Functional disturbances in the striatum by region-specific ablation of NMDA receptors. Proceedings of the National Academy of Sciences of the United States of America. 105: 12961-6. PMID 18728179 DOI: 10.1073/Pnas.0806180105  0.747
2008 Lai JP, Lai S, Tuluc F, Tansky MF, Kilpatrick LE, Leeman SE, Douglas SD. Differences in the length of the carboxyl terminus mediate functional properties of neurokinin-1 receptor. Proceedings of the National Academy of Sciences of the United States of America. 105: 12605-10. PMID 18713853 DOI: 10.1073/Pnas.0806632105  0.77
2008 Lim R, Morrill JM, Prushik SG, Reed KL, Gower AC, Leeman SE, Stucchi AF, Becker JM. An FDA approved neurokinin-1 receptor antagonist is effective in reducing intraabdominal adhesions when administered intraperitoneally, but not orally. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 12: 1754-61. PMID 18709513 DOI: 10.1007/S11605-008-0634-4  0.366
2008 Lim R, Morrill JM, Reed KL, Gower AC, McCloud B, Leeman SE, Stucchi AF, Becker JM. 560 A Neurokinin-1 Receptor Antagonist (NK1RA) That Reduces Intraabdominal Adhesions Augments the Anti-Adhesive Effects of a Hyaluronic Acid/Carboxymethylcellulose (HA/CMC) Adhesion Barrier in Rats Gastroenterology. 134: A-849. DOI: 10.1016/S0016-5085(08)63978-5  0.321
2008 Lim R, Prushik SG, Morrill JM, Reed KL, Gower AC, Leeman SE, Stucchi AF, Becker JM. 32. A Clinically Approved Neurokinin 1 Receptor Antagonist (NK-1RA) Is Effective in Preventing Intraabdominal Adhesions When Administered Intraperitoneally But Not Orally Journal of Surgical Research. 144: 189-190. DOI: 10.1016/J.Jss.2007.12.037  0.321
2007 Chen CD, Podvin S, Gillespie E, Leeman SE, Abraham CR. Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proceedings of the National Academy of Sciences of the United States of America. 104: 19796-801. PMID 18056631 DOI: 10.1073/Pnas.0709805104  0.577
2007 Tansky MF, Pothoulakis C, Leeman SE. Functional consequences of alteration of N-linked glycosylation sites on the neurokinin 1 receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 10691-6. PMID 17563389 DOI: 10.1073/Pnas.0703394104  0.767
2007 Prushik SG, Aarons CB, Matteotti R, Reed KL, Gower AC, Leeman SE, Stucchi AF, Becker JM. A neurokinin 1 receptor antagonist decreases adhesion reformation after laparoscopic lysis of adhesions in a rat model of adhesion formation. Surgical Endoscopy. 21: 1790-5. PMID 17356938 DOI: 10.1007/S00464-007-9248-2  0.362
2007 Cohen PA, Aarons CB, Gower AC, Stucchi AF, Leeman SE, Becker JM, Reed KL. The effectiveness of a single intraperitoneal infusion of a neurokinin-1 receptor antagonist in reducing postoperative adhesion formation is time dependent. Surgery. 141: 368-75. PMID 17349849 DOI: 10.1016/J.Surg.2006.09.007  0.354
2007 Aarons CB, Cohen PA, Gower A, Reed KL, Leeman SE, Stucchi AF, Becker JM. Statins (HMG-CoA reductase inhibitors) decrease postoperative adhesions by increasing peritoneal fibrinolytic activity. Annals of Surgery. 245: 176-84. PMID 17245169 DOI: 10.1097/01.Sla.0000236627.07927.7C  0.317
2006 Stucchi A, Reed K, O'Brien M, Cerda S, Andrews C, Gower A, Bushell K, Amar S, Leeman S, Becker J. A new transcription factor that regulates TNF-alpha gene expression, LITAF, is increased in intestinal tissues from patients with CD and UC. Inflammatory Bowel Diseases. 12: 581-7. PMID 16804395 DOI: 10.1097/01.Mib.0000225338.14356.D5  0.743
2006 Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O'Brien M, Leeman SE, Kirkland JL, Pothoulakis C. Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 5207-12. PMID 16549770 DOI: 10.1073/Pnas.0600821103  0.768
2004 Reed KL, Fruin AB, Gower AC, Stucchi AF, Leeman SE, Becker JM. A neurokinin 1 receptor antagonist decreases postoperative peritoneal adhesion formation and increases peritoneal fibrinolytic activity. Proceedings of the National Academy of Sciences of the United States of America. 101: 9115-20. PMID 15187234 DOI: 10.1073/Pnas.0403210101  0.374
2003 Stucchi AF, Shebani KO, Leeman SE, Wang CC, Reed KL, Fruin AB, Gower AC, McClung JP, Andry CD, O'Brien MJ, Pothoulakis C, Becker JM. A neurokinin 1 receptor antagonist reduces an ongoing ileal pouch inflammation and the response to a subsequent inflammatory stimulus. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G1259-67. PMID 12893626 DOI: 10.1152/Ajpgi.00063.2003  0.374
2003 Kennedy PG, Rodgers J, Bradley B, Hunt SP, Gettinby G, Leeman SE, de Felipe C, Murray M. Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice. Brain : a Journal of Neurology. 126: 1683-90. PMID 12805119 DOI: 10.1093/Brain/Awg160  0.355
2003 Reed KL, Lehrmann JF, Stucchi AF, Gower AC, Leeman SE, Becker JM. Administration of a substance P receptor antagonist (SPRA) increases the expression of peritoneal tissue plasminogen activator (tPA) in rat model of intraabdominal adhesions Gastroenterology. 124: A299. DOI: 10.1016/S0016-5085(03)81508-1  0.394
2002 Reed KL, Fruin AB, Bishop-Bartolomei KK, Gower AC, Nicolaou M, Stucchi AF, Leeman SE, Becker JM. Neurokinin-1 receptor and substance P messenger RNA levels increase during intraabdominal adhesion formation. The Journal of Surgical Research. 108: 165-72. PMID 12443729 DOI: 10.1006/Jsre.2002.6533  0.389
2001 Bremer AA, Tansky MF, Wu M, Boyd ND, Leeman SE. Direct evidence for the interaction of neurokinin A with the tachykinin NK(1) receptor in tissue. European Journal of Pharmacology. 423: 143-7. PMID 11448478 DOI: 10.1016/S0014-2999(01)01107-4  0.767
2001 Macdonald D, Mierke DF, Li H, Pellegrini M, Sachais B, Krause JE, Leeman SE, Boyd ND. Photoaffinity labeling of mutant neurokinin-1 receptors reveals additional structural features of the substance P/NK-1 receptor complex. Biochemistry. 40: 2530-9. PMID 11327875 DOI: 10.1021/Bi001880X  0.585
2001 Bremer AA, Leeman SE, Boyd ND. Evidence for spatial proximity of two distinct receptor regions in the substance P (SP)*neurokinin-1 receptor (NK-1R) complex obtained by photolabeling the NK-1R with p-benzoylphenylalanine3-SP. The Journal of Biological Chemistry. 276: 22857-61. PMID 11294866 DOI: 10.1074/Jbc.M100824200  0.401
2001 Li H, Macdonald DM, Hronowski X, Costello CE, Leeman SE, Boyd ND. Further definition of the substance P (SP)/neurokinin-1 receptor complex. MET-174 is the site of photoinsertion p-benzoylphenylalanine4 SP. The Journal of Biological Chemistry. 276: 10589-93. PMID 11116140 DOI: 10.1074/Jbc.M007397200  0.574
2000 Bremer AA, Leeman SE, Boyd ND. The common C-terminal sequences of substance P and neurokinin A contact the same region of the NK-1 receptor. Febs Letters. 486: 43-8. PMID 11108840 DOI: 10.1016/S0014-5793(00)02228-6  0.393
2000 Stucchi AF, Shofer S, Leeman S, Materne O, Beer E, McClung J, Shebani K, Moore F, O'Brien M, Becker JM. NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G1298-306. PMID 11093954 DOI: 10.1152/Ajpgi.2000.279.6.G1298  0.374
2000 Shebani KO, Stucchi AF, Leeman S, Pothoulakis C, McClung J, Beer E, LaMorte W, Becker JM. Upregulation of neurokinin 1 (NK-1) receptors mediates pouch inflammation in a rat model of ileal j pouch-anal anastomosis (IPAA) Journal of the American College of Surgeons. 191: S55-S56. DOI: 10.1016/S1072-7515(00)00544-5  0.386
1999 Benoliel R, Eliav E, Mannes AJ, Caudle RM, Leeman S, Iadarola MJ. Actions of intrathecal diphtheria toxin-substance P fusion protein on models of persistent pain. Pain. 79: 243-53. PMID 10068170 DOI: 10.1016/S0304-3959(98)00170-5  0.338
1998 Alexander MJ, Leeman SE. Widespread expression in adult rat forebrain of mRNA encoding high-affinity neurotensin receptor. The Journal of Comparative Neurology. 402: 475-500. PMID 9862322 DOI: 10.1002/(Sici)1096-9861(19981228)402:4<475::Aid-Cne4>3.0.Co;2-9  0.359
1998 Pothoulakis C, Castagliuolo I, Leeman SE, Wang CC, Li H, Hoffman BJ, Mezey E. Substance P receptor expression in intestinal epithelium in clostridium difficile toxin A enteritis in rats. The American Journal of Physiology. 275: G68-75. PMID 9655686 DOI: 10.1152/Ajpgi.1998.275.1.G68  0.386
1998 Pothoulakis C, Castagliuolo I, Leeman SE. Neuroimmune mechanisms of intestinal responses to stress. Role of corticotropin-releasing factor and neurotensin. Annals of the New York Academy of Sciences. 840: 635-48. PMID 9629290 DOI: 10.1111/J.1749-6632.1998.Tb09602.X  0.303
1997 Li H, Leeman SE, Slack BE, Hauser G, Saltsman WS, Krause JE, Blusztajn JK, Boyd ND. A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. Proceedings of the National Academy of Sciences of the United States of America. 94: 9475-80. PMID 9256507 DOI: 10.1073/Pnas.94.17.9475  0.42
1997 Castagliuolo I, Keates AC, Qiu B, Kelly CP, Nikulasson S, Leeman SE, Pothoulakis C. Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proceedings of the National Academy of Sciences of the United States of America. 94: 4788-93. PMID 9114070 DOI: 10.1073/Pnas.94.9.4788  0.392
1997 Kennedy PG, Rodgers J, Jennings FW, Murray M, Leeman SE, Burke JM. A substance P antagonist, RP-67,580, ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei. Proceedings of the National Academy of Sciences of the United States of America. 94: 4167-70. PMID 9108123 DOI: 10.1073/Pnas.94.8.4167  0.387
1997 Kohlmann O, Cesaretti ML, Ginoza M, Tavares A, Zanella MT, Ribeiro AB, Ramos OL, Leeman SE, Gavras I, Gavras H. Role of substance P in blood pressure regulation in salt-dependent experimental hypertension. Hypertension. 29: 506-9. PMID 9039150 DOI: 10.1161/01.Hyp.29.1.506  0.311
1997 Leeman SE, Boyd ND. Chapter 7 Substance P Principles of Medical Biology. 8: 133-139. DOI: 10.1016/S1569-2582(97)80069-4  0.363
1996 Castagliuolo I, Leeman SE, Bartolak-Suki E, Nikulasson S, Qiu B, Carraway RE, Pothoulakis C. A neurotensin antagonist, SR 48692, inhibits colonic responses to immobilization stress in rats. Proceedings of the National Academy of Sciences of the United States of America. 93: 12611-5. PMID 8901630 DOI: 10.1073/Pnas.93.22.12611  0.36
1996 Rittenhouse PA, Marchand JE, Chen J, Kream RM, Leeman SE. Streptozotocin-induced diabetes is associated with altered expression of peptide-encoding mRNAs in rat sensory neurons. Peptides. 17: 1017-22. PMID 8899822 DOI: 10.1016/0196-9781(96)00129-5  0.317
1996 Rittenhouse PA, Markle RA, Marchand JE, Kream RM, Leeman SE. Streptozotocin-induced diabetes produces a decrease in pituitary substance P content and preprotachykinin mRNA. Neuroscience Letters. 211: 77-80. PMID 8830848 DOI: 10.1016/0304-3940(96)12727-0  0.323
1996 Kage R, Leeman SE, Krause JE, Costello CE, Boyd ND. Identification of methionine as the site of covalent attachment of a p-benzoyl-phenylalanine-containing analogue of substance P on the substance P (NK-1) receptor. The Journal of Biological Chemistry. 271: 25797-800. PMID 8824208 DOI: 10.1074/Jbc.271.42.25797  0.403
1996 Fisher CE, Sutherland JA, Krause JE, Murphy JR, Leeman SE, vanderSpek JC. Genetic construction and properties of a diphtheria toxin-related substance P fusion protein: in vitro destruction of cells bearing substance P receptors. Proceedings of the National Academy of Sciences of the United States of America. 93: 7341-5. PMID 8692995 DOI: 10.1073/Pnas.93.14.7341  0.695
1996 MacDonald D, Silberman SC, Lowe JA, Drozda SE, Leeman SE, Boyd ND. Photoaffinity labeling of the human substance P (neurokinin-1) receptor with [3H2]azido-CP-96,345, a photoreactive derivative of a nonpeptide antagonist. Molecular Pharmacology. 49: 808-13. PMID 8622630  0.537
1996 Li H, Hsu P, Sachais BS, Krause JE, Leeman SE, Boyd ND. Identification of the site in the substance P (NK-1) receptor for modulation of peptide binding by sulfhydryl reagents. The Journal of Biological Chemistry. 271: 1950-6. PMID 8567643 DOI: 10.1074/Jbc.271.4.1950  0.403
1996 Boyd ND, Kage R, Dumas JJ, Krause JE, Leeman SE. The peptide binding site of the substance P (NK-1) receptor localized by a photoreactive analogue of substance P: presence of a disulfide bond. Proceedings of the National Academy of Sciences of the United States of America. 93: 433-7. PMID 8552654 DOI: 10.1073/Pnas.93.1.433  0.408
1995 Chancellor-Freeland C, Zhu GF, Kage R, Beller DI, Leeman SE, Black PH. Substance P and stress-induced changes in macrophages. Annals of the New York Academy of Sciences. 771: 472-84. PMID 8597423 DOI: 10.1111/J.1749-6632.1995.Tb44703.X  0.362
1995 Boyd ND, Kage R, Dumas JJ, Silberman SC, Krause JE, Leeman SE. Localization of the peptide binding domain of the NK-1 tachykinin receptor using photoreactive analogues of substance P. Annals of the New York Academy of Sciences. 757: 405-9. PMID 7541973 DOI: 10.1111/J.1749-6632.1995.Tb17498.X  0.357
1995 Kage R, Hershey AD, Krause JE, Boyd ND, Leeman SE. Characterization of the substance P (NK-1) receptor in tunicamycin-treated transfected cells using a photoaffinity analogue of substance P. Journal of Neurochemistry. 64: 316-21. PMID 7528264 DOI: 10.1046/J.1471-4159.1995.64010316.X  0.403
1995 Kohlmann O, Ginoza M, Cezaretti ML, Zanella MT, Ribeiro AB, Tavares A, Ramos OL, Leeman SE, Gavras I, Gavras H. Cardiovascular effects of a specific nonpeptide antagonist of substance P (NK-1) receptor in DOCA-salt hypertension. Hypertension. 26: 1186-9. PMID 7498993 DOI: 10.1161/01.Hyp.26.6.1186  0.315
1994 Vijayan E, Carraway R, Leeman SE, McCann SM. Physiological significance of neurotensin in pituitary glycoprotein hormone release as revealed by in vivo and in vitro studies with neurotensin antiserum. Neuroendocrinology. 60: 157-64. PMID 7969773 DOI: 10.1159/000126746  0.315
1994 Alexander MJ, Leeman SE. Estrogen-inducible neurotensin immunoreactivity in the preoptic area of the female rat. The Journal of Comparative Neurology. 345: 496-509. PMID 7962697 DOI: 10.1002/Cne.903450403  0.316
1994 Pothoulakis C, Castagliuolo I, LaMont JT, Jaffer A, O'Keane JC, Snider RM, Leeman SE. CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proceedings of the National Academy of Sciences of the United States of America. 91: 947-51. PMID 7508124 DOI: 10.1073/Pnas.91.3.947  0.384
1993 Kage R, Leeman SE, Boyd ND. Biochemical characterization of two different forms of the substance P receptor in rat submaxillary gland. Journal of Neurochemistry. 60: 347-51. PMID 8380195 DOI: 10.1111/J.1471-4159.1993.Tb05857.X  0.328
1992 Leeman SE, Munson PL. Thoughts concerning women in science. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 3327. PMID 1464367 DOI: 10.1096/Fasebj.6.15.1464367  0.537
1992 Shamgochian MD, Leeman SE. Substance P stimulates luteinizing hormone secretion from anterior pituitary cells in culture. Endocrinology. 131: 871-5. PMID 1379165 DOI: 10.1210/Endo.131.2.1379165  0.353
1992 Luber-Narod J, Kage R, Leeman SE. SUBSTANCE P (SP) AUGMENTS THE SECRETION OF TUMOR NECROSIS FACTOR (TNF) FROM GLIAL CELLS IN A SYNERGISTIC MANNER. Clinical Neuropharmacology. 15: 72B. DOI: 10.1097/00002826-199202001-00139  0.331
1991 Chung ES, Leeman SE, Cuénoud HF. The effect of neonatal treatment with capsaicin on focal arteriolar insudation. Microvascular Research. 42: 316-24. PMID 1779885 DOI: 10.1016/0026-2862(91)90065-J  0.321
1991 Snider RM, Longo KP, Drozda SE, Lowe JA, Leeman SE. Effect of CP-96,345, a nonpeptide substance P receptor antagonist, on salivation in rats. Proceedings of the National Academy of Sciences of the United States of America. 88: 10042-4. PMID 1719543 DOI: 10.1073/Pnas.88.22.10042  0.357
1991 Boyd ND, MacDonald SG, Kage R, Luber-Narod J, Leeman SE. Substance P receptor. Biochemical characterization and interactions with G proteins. Annals of the New York Academy of Sciences. 632: 79-93. PMID 1659301 DOI: 10.1111/J.1749-6632.1991.Tb33096.X  0.341
1990 Luber-Narod J, Boyd ND, Leeman SE. Guanine nucleotides decrease the affinity of substance P binding to its receptor. European Journal of Pharmacology. 188: 185-91. PMID 1694776 DOI: 10.1016/0922-4106(90)90001-E  0.326
1990 Oblas B, Boyd ND, Luber-Narod J, Reyes VE, Leeman SE. Isolation and identification of a polypeptide in the Hsp 70 family that binds substance P. Biochemical and Biophysical Research Communications. 166: 978-83. PMID 1689156 DOI: 10.1016/0006-291X(90)90907-5  0.315
1989 Alexander MJ, Dobner PR, Miller MA, Bullock BP, Dorsa DM, Leeman SE. Estrogen induces neurotensin/neuromedin N messenger ribonucleic acid in a preoptic nucleus essential for the preovulatory surge of luteinizing hormone in the rat. Endocrinology. 125: 2111-7. PMID 2791980 DOI: 10.1210/Endo-125-4-2111  0.327
1989 Barber DL, Buchan AM, Leeman SE, Soll AH. Canine enteric submucosal cultures: transmitter release from neurotensin-immunoreactive neurons. Neuroscience. 32: 245-53. PMID 2511502 DOI: 10.1016/0306-4522(89)90123-1  0.312
1989 Prabhakar NR, Landis SC, Kumar GK, Mullikin-Kilpatrick D, Cherniack NS, Leeman S. Substance P and neurokinin A in the cat carotid body: localization, exogenous effects and changes in content in response to arterial pO2. Brain Research. 481: 205-14. PMID 2470465 DOI: 10.1016/0006-8993(89)90795-6  0.311
1988 Vijayan E, Carraway R, Leeman SE, McCann SM. Use of antiserum to neurotensin reveals a physiological role for the peptide in rat prolactin release. Proceedings of the National Academy of Sciences of the United States of America. 85: 9866-9. PMID 3200862 DOI: 10.1073/Pnas.85.24.9866  0.304
1988 Naftchi NE, Maker H, Lapin E, Sleis J, Lajtha A, Leeman S. Acute reduction of brain substance P induced by nicotine. Neurochemical Research. 13: 305-9. PMID 2455873 DOI: 10.1007/Bf00972478  0.311
1988 Armstrong MJ, Leeman SE. Neurotensin and Substance P Advances in Metabolic Disorders. 11: 469-492. DOI: 10.1016/B978-0-12-027311-9.50020-2  0.352
1987 Canick JA, Tobet SA, Baum MJ, Vaccaro DE, Ryan KJ, Leeman SE, Fox TO. Studies on the role of catecholamines in the regulation of the developmental pattern of hypothalamic aromatase. Steroids. 50: 509-21. PMID 3504614 DOI: 10.1016/0039-128X(87)90035-3  0.305
1987 Jonassen JA, Mullikin-Kilpatrick D, McAdam A, Leeman SE. Thyroid hormone status regulates preprotachykinin-A gene expression in male rat anterior pituitary. Endocrinology. 121: 1555-61. PMID 2820702 DOI: 10.1210/Endo-121-4-1555  0.334
1987 Boyd ND, Leeman SE. Multiple actions of substance P that regulate the functional properties of acetylcholine receptors of clonal rat PC12 cells. The Journal of Physiology. 389: 69-97. PMID 2445982 DOI: 10.1113/Jphysiol.1987.Sp016647  0.384
1986 Armstrong MJ, Parker MC, Ferris CF, Leeman SE. Neurotensin stimulates [3H]oleic acid translocation across rat small intestine. The American Journal of Physiology. 251: G823-9. PMID 3789148 DOI: 10.1152/Ajpgi.1986.251.6.G823  0.302
1986 Aronin N, Coslovsky R, Leeman SE. Substance P and neurotensin: their roles in the regulation of anterior pituitary function. Annual Review of Physiology. 48: 537-49. PMID 2423025 DOI: 10.1146/Annurev.Ph.48.030186.002541  0.319
1985 Ferris CF, Parker MC, Armstrong MJ, Leeman SE. Inhibition of neurotensin release by a cyclic hexapeptide analog of somatostatin. Peptides. 6: 945-8. PMID 2867526 DOI: 10.1016/0196-9781(85)90326-2  0.329
1985 Coslovsky R, Braverman LE, Leeman SE, Aronin N. The differential effects of thyroid and gonadal hormones on substance P content in the anterior pituitary of the prepubertal rat. Endocrinology. 117: 2198-202. PMID 2412805 DOI: 10.1210/Endo-117-5-2198  0.31
1984 Ferris CF, Pan JX, Singer EA, Boyd ND, Carraway RE, Leeman SE. Stimulation of luteinizing hormone release after stereotaxic microinjection of neurotensin into the medial preoptic area of rats. Neuroendocrinology. 38: 145-51. PMID 6717745 DOI: 10.1159/000123882  0.328
1984 Coslovsky R, Evans RW, Leeman SE, Braverman LE, Aronin N. The effects of gonadal steroids on the content of substance P in the rat anterior pituitary. Endocrinology. 115: 2285-9. PMID 6209122 DOI: 10.1210/Endo-115-6-2285  0.324
1984 Aronin N, Morency K, Leeman SE, Braverman LE, Coslovsky R. Regulation by thyroid hormone of the concentration of substance P in the rat anterior pituitary. Endocrinology. 114: 2138-42. PMID 6202496 DOI: 10.1210/Endo-114-6-2138  0.317
1983 Aronin N, Cooper PE, Lorenz LJ, Bird ED, Sagar SM, Leeman SE, Martin JB. Somatostatin is increased in the basal ganglia in Huntington disease. Annals of Neurology. 13: 519-26. PMID 6191621 DOI: 10.1002/Ana.410130508  0.304
1982 Leeman SE, Aronin N, Ferris C. Substance P and neurotensin. Recent Progress in Hormone Research. 38: 93-132. PMID 6181544 DOI: 10.1007/978-1-4613-4130-7_5  0.302
1982 Floor E, Grad O, Leeman SE. Synaptic vesicles containing substance P purified by chromatography on controlled pore glass. Neuroscience. 7: 1647-55. PMID 6181432 DOI: 10.1016/0306-4522(82)90023-9  0.326
1982 Carraway R, Cochrane DE, Lansman JB, Leeman SE, Paterson BM, Welch HJ. Neurotensin stimulates exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels. The Journal of Physiology. 323: 403-14. PMID 6178820 DOI: 10.1113/Jphysiol.1982.Sp014080  0.335
1981 Role LW, Leeman SE, Perlman RL. Somatostatin and substance P inhibit catecholamine secretion from isolated cells of guinea-pig adrenal medulla. Neuroscience. 6: 1813-21. PMID 6170913 DOI: 10.1016/0306-4522(81)90215-3  0.351
1981 Gamse R, Leeman SE, Holzer P, Lembeck F. Differential effects of capsaicin on the content of somatostatin, substance P, and neurotensin in the nervous system of the rat. Naunyn-Schmiedeberg's Archives of Pharmacology. 317: 140-8. PMID 6170896 DOI: 10.1007/Bf00500070  0.353
1981 Gamse R, Lackner D, Gamse G, Leeman SE. Effect of capsaicin pretreatment on capsaicin-evoked release of immunoreactive somatostatin and substance P from primary sensory neurons. Naunyn-Schmiedeberg's Archives of Pharmacology. 316: 38-41. PMID 6168921 DOI: 10.1007/Bf00507224  0.329
1981 Gamse R, Wax A, Zigmond RE, Leeman SE. Immunoreactive substance P in sympathetic ganglia: distribution and sensitivity towards capsaicin. Neuroscience. 6: 437-41. PMID 6164015 DOI: 10.1016/0306-4522(81)90136-6  0.332
1980 ZeytinoÄŸlu FN, Gagel RF, Tashjian AH, Hammer RA, Leeman SE. Characterization of neurotensin production by a line of rat medullary thyroid carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 77: 3741-5. PMID 6932046 DOI: 10.1073/Pnas.77.6.3741  0.312
1980 Pettibone DJ, Wurtman RJ, Leeman SE. Striatal substance P-like immunoreactivity: characterization of high-performance liquid chromatography and aspects of subcellular distribution and in vitro release by potassium. Life Sciences. 27: 1593-602. PMID 6160368 DOI: 10.1016/0024-3205(80)90569-X  0.323
1980 Yaksh TL, Jessell TM, Gamse R, Mudge AW, Leeman SE. Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature. 286: 155-7. PMID 6157098 DOI: 10.1038/286155A0  0.312
1980 Floor E, Leeman SE. Substance P sulfoxide: separation from substance P by high-pressure liquid chromatography, biological and immunological activities, and chemical reduction. Analytical Biochemistry. 101: 498-503. PMID 6153871 DOI: 10.1016/0003-2697(80)90220-1  0.325
1979 Guyenet PG, Mroz EA, Aghajanian GK, Leeman SE. Delayed iontophoretic ejection of substance P from glass micropipettes: correlation with time-course of neuronal excitation in vivo. Neuropharmacology. 18: 553-8. PMID 481708 DOI: 10.1016/0028-3908(79)90100-X  0.335
1979 Yaksh TL, Farb DH, Leeman SE, Jessell TM. Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science (New York, N.Y.). 206: 481-3. PMID 228392 DOI: 10.1126/Science.228392  0.607
1979 Mudge AW, Leeman SE, Fischbach GD. Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration. Proceedings of the National Academy of Sciences of the United States of America. 76: 526-30. PMID 218204 DOI: 10.1073/Pnas.76.1.526  0.585
1978 Pettibone DJ, Wurtman RJ, Leeman SE. D-amphetamine administration reduces substance P concentration in the rat striatum. Biochemical Pharmacology. 27: 839-12. PMID 656130 DOI: 10.1016/0006-2952(78)90541-5  0.303
1977 Mroz EA, Brownstein MJ, Leeman SE. Evidence for substance P in the striato-nigral tract. Brain Research. 125: 305-11. PMID 856411 DOI: 10.1016/0006-8993(77)90623-0  0.314
1976 Brownstein MJ, Mroz EA, Kizer JS, Palkovits M, Leeman SE. Regional distribution of substance P in the brain of the rat. Brain Research. 116: 299-305. PMID 974776 DOI: 10.1016/0006-8993(76)90907-0  0.306
1976 Mroz ED, Brownstein MJ, Leeman SE. Evidence for substance P in the habenulo-interpeduncular tract. Brain Research. 113: 597-9. PMID 953755 DOI: 10.1016/0006-8993(76)90061-5  0.301
1976 Schenker C, Mroz EA, Leeman SE. Release of substance P from isolated nerve endings. Nature. 264: 790-2. PMID 13307 DOI: 10.1038/264790A0  0.312
1974 Takahashi T, Konishi S, Powell D, Leeman SE, Otsuka M. Identification of the motoneuron-depolarizing peptide in bovine dorsal root as hypothalamic substance P. Brain Research. 73: 59-69. PMID 4407840 DOI: 10.1016/0006-8993(74)91007-5  0.302
1973 Powell D, Leeman S, Tregear GW, Niall HD, Potts JT. Radioimmunoassay for substance P. Nature: New Biology. 241: 252-4. PMID 4512485 DOI: 10.1038/Newbio241252A0  0.336
1971 Chang MM, Leeman SE, Niall HD. Amino-acid sequence of substance P. Nature: New Biology. 232: 86-7. PMID 5285346 DOI: 10.1038/Newbio232086A0  0.312
1967 Leeman SE, Hammerschlag R. Stimulation of salivary secretion by a factor extracted from hypothalamic tissue. Endocrinology. 81: 803-10. PMID 6042694 DOI: 10.1210/Endo-81-4-803  0.31
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