Gareth Tibbs - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Neuroscience Biology

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Joyce RL, Tibbs GR, David Warren J, Costa CJ, Aromolaran K, Lea Sanford R, Andersen OS, Li Z, Zhang G, Willis DE, Goldstein PA. Probucol is anti-hyperalgesic in a mouse peripheral nerve injury model of neuropathic pain. Neurobiology of Pain (Cambridge, Mass.). 14: 100141. PMID 38099280 DOI: 10.1016/j.ynpai.2023.100141  0.351
2019 Joyceadat RL, Beyer NP, Vasilopoulos G, Woll K, Hall AC, Eckenhoff RG, Barman DN, David Warren J, Tibbs GR, Goldstein PA. Alkylphenol inverse agonists of HCN1 gating: H-bond propensity, ring saturation and adduct geometry differentially determine efficacy and potency. Biochemical Pharmacology. PMID 30768926 DOI: 10.1016/J.Bcp.2019.02.013  0.488
2018 Riegelhaupt PM, Tibbs GR, Goldstein PA. HCN and KChannels in Anesthetic Mechanisms Research. Methods in Enzymology. 602: 391-416. PMID 29588040 DOI: 10.1016/Bs.Mie.2018.01.015  0.433
2016 Tibbs GR, Posson DJ, Goldstein PA. Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain? Trends in Pharmacological Sciences. PMID 27233519 DOI: 10.1016/J.Tips.2016.05.002  0.35
2014 Lyashchenko AK, Redd KJ, Goldstein PA, Tibbs GR. cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore. Plos One. 9: e101236. PMID 24983358 DOI: 10.1371/Journal.Pone.0101236  0.69
2013 Tibbs GR, Rowley TJ, Sanford RL, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD. HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 345: 363-73. PMID 23549867 DOI: 10.1124/Jpet.113.203620  0.553
2011 Ying SW, Tibbs GR, Picollo A, Abbas SY, Sanford RL, Accardi A, Hofmann F, Ludwig A, Goldstein PA. PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10412-23. PMID 21753018 DOI: 10.1523/Jneurosci.0021-11.2011  0.552
2009 Rozario AO, Turbendian HK, Fogle KJ, Olivier NB, Tibbs GR. Voltage-dependent opening of HCN channels: Facilitation or inhibition by the phytoestrogen, genistein, is determined by the activation status of the cyclic nucleotide gating ring. Biochimica Et Biophysica Acta. 1788: 1939-49. PMID 19524546 DOI: 10.1016/J.Bbamem.2009.06.003  0.731
2009 Bell DC, Turbendian HK, Valley MT, Zhou L, Riley JH, Siegelbaum SA, Tibbs GR. Probing S4 and S5 segment proximity in mammalian hyperpolarization-activated HCN channels by disulfide bridging and Cd2+ coordination. PflüGers Archiv : European Journal of Physiology. 458: 259-72. PMID 19034494 DOI: 10.1007/S00424-008-0613-3  0.592
2008 Lyashchenko AK, Tibbs GR. Ion binding in the open HCN pacemaker channel pore: fast mechanisms to shape "slow" channels. The Journal of General Physiology. 131: 227-43. PMID 18270171 DOI: 10.1085/Jgp.200709868  0.525
2007 Lyashchenko AK, Redd KJ, Yang J, Tibbs GR. Propofol inhibits HCN1 pacemaker channels by selective association with the closed states of the membrane embedded channel core. The Journal of Physiology. 583: 37-56. PMID 17569731 DOI: 10.1113/Jphysiol.2007.136465  0.687
2007 Fogle KJ, Lyashchenko AK, Turbendian HK, Tibbs GR. HCN pacemaker channel activation is controlled by acidic lipids downstream of diacylglycerol kinase and phospholipase A2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2802-14. PMID 17360902 DOI: 10.1523/Jneurosci.4376-06.2007  0.693
2005 Cacheaux LP, Topf N, Tibbs GR, Schaefer UR, Levi R, Harrison NL, Abbott GW, Goldstein PA. Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol. The Journal of Pharmacology and Experimental Therapeutics. 315: 517-25. PMID 16033909 DOI: 10.1124/Jpet.105.091801  0.722
2001 Wainger BJ, DeGennaro M, Santoro B, Siegelbaum SA, Tibbs GR. Molecular mechanism of cAMP modulation of HCN pacemaker channels. Nature. 411: 805-10. PMID 11459060 DOI: 10.1038/35081088  0.765
2000 Santoro B, Chen S, Lüthi A, Pavlidis P, Shumyatsky GP, Tibbs GR, Siegelbaum SA. Molecular and Functional Heterogeneity of Hyperpolarization-Activated Pacemaker Channels in the Mouse CNS The Journal of Neuroscience. 20: 5264-5275. DOI: 10.1523/JNEUROSCI.20-14-05264.2000  0.636
1999 Santoro B, Tibbs GR. The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels. Annals of the New York Academy of Sciences. 868: 741-64. PMID 10414361 DOI: 10.1111/j.1749-6632.1999.tb11353.x  0.73
1998 Liu DT, Tibbs GR, Paoletti P, Siegelbaum SA. Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers. Neuron. 21: 235-48. PMID 9697867 DOI: 10.1016/S0896-6273(00)80530-9  0.575
1998 Santoro B, Liu DT, Yao H, Bartsch D, Kandel ER, Siegelbaum SA, Tibbs GR. Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell. 93: 717-29. PMID 9630217 DOI: 10.1016/S0092-8674(00)81434-8  0.592
1998 Tibbs GR, Liu DT, Leypold BG, Siegelbaum SA. A state-independent interaction between ligand and a conserved arginine residue in cyclic nucleotide-gated channels reveals a functional polarity of the cyclic nucleotide binding site. The Journal of Biological Chemistry. 273: 4497-505. PMID 9468504 DOI: 10.1074/jbc.273.8.4497  0.643
1997 Tibbs GR, Goulding EH, Siegelbaum SA. Allosteric activation and tuning of ligand efficacy in cyclic-nucleotide-gated channels. Nature. 386: 612-5. PMID 9121585 DOI: 10.1038/386612a0  0.685
1996 Liu DT, Tibbs GR, Siegelbaum SA. Subunit stoichiometry of cyclic nucleotide-gated channels and effects of subunit order on channel function. Neuron. 16: 983-90. PMID 8630256 DOI: 10.1016/S0896-6273(00)80121-X  0.716
1996 Kramer R, Tibbs G. Antagonists of cyclic nucleotide-gated channels and molecular mapping of their site of action The Journal of Neuroscience. 16: 1285-1293. DOI: 10.1523/jneurosci.16-04-01285.1996  0.571
1994 Goulding EH, Tibbs GR, Siegelbaum SA. Molecular mechanism of cyclic-nucleotide-gated channel activation. Nature. 372: 369-74. PMID 7969497 DOI: 10.1038/372369a0  0.753
1994 Hall A, Tibbs G, Dolly J, Lieb W, Franks N. A simple method for recording single-channel activity from synaptic plasma membranes Journal of Pharmacological and Toxicological Methods. 31: 173. DOI: 10.1016/1056-8719(94)90083-3  0.459
1993 Hall AC, Tibbs GR, Dolly JO, Lieb WR, Franks NP. A simple method for recording single-channel activity from synaptic plasma membranes. Journal of Neuroscience Methods. 49: 81-91. PMID 8271834 DOI: 10.1016/0165-0270(93)90111-4  0.579
1993 Goulding EH, Tibbs GR, Liu D, Siegelbaum SA. Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels. Nature. 364: 61-4. PMID 7686276 DOI: 10.1038/364061a0  0.646
1990 Muniz ZM, Tibbs GR, Maschot P, Bougis P, Nicholls DG, Dolly JO. Homologues of a K+ channel blocker α-dendrotoxin: characterization of synaptosomal binding sites and their coupling to elevation of cytosolic free calcium concentration Neurochemistry International. 16: 105-112. DOI: 10.1016/0197-0186(90)90130-L  0.436
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