David W.C. MacMillan - Publications

Affiliations: 
2000-2006 California Institute of Technology, Pasadena, CA 
 2006- Princeton University, Princeton, NJ 
Area:
Organic Synthesis, enantioselective catalysis
Website:
http://www.princeton.edu/chemistry/macmillan/david-macmillan/

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Smith RT, Zhang X, Rincon JA, Agejas J, Mateos C, Barberis M, García-Cerrada S, de Frutos O, MacMillan DWC. Metallaphotoredox-Catalyzed Cross-Electrophile Csp3-Csp3 Coupling of Aliphatic Bromides. Journal of the American Chemical Society. PMID 30516995 DOI: 10.1021/jacs.8b12025  1
2018 Perry IB, Brewer TF, Sarver PJ, Schultz DM, DiRocco DA, MacMillan DWC. Direct arylation of strong aliphatic C-H bonds. Nature. 560: 70-75. PMID 30068953 DOI: 10.1038/s41586-018-0366-x  0.68
2018 Liang Y, Zhang X, MacMillan DWC. Decarboxylative sp C-N coupling via dual copper and photoredox catalysis. Nature. PMID 29925943 DOI: 10.1038/s41586-018-0234-8  1
2018 Le C, Chen TQ, Liang T, Zhang P, MacMillan DWC. A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes. Science (New York, N.Y.). 360: 1010-1014. PMID 29853683 DOI: 10.1126/science.aat4133  0.96
2018 Kautzky JA, Wang T, Evans RW, MacMillan DWC. Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids. Journal of the American Chemical Society. PMID 29754491 DOI: 10.1021/jacs.8b02650  0.68
2018 Till NA, Smith RT, MacMillan DWC. Decarboxylative Hydroalkylation of Alkynes. Journal of the American Chemical Society. PMID 29664294 DOI: 10.1021/jacs.8b02834  0.32
2018 Twilton J, Christensen M, DiRocco DA, Ruck RT, Davies IW, MacMillan DW. Selective Hydrogen Atom Abstraction via Induced Bond Polarization: The Direct -Arylation of Alcohols via Photoredox, HAT and Nickel Catalysis. Angewandte Chemie (International Ed. in English). PMID 29490112 DOI: 10.1002/anie.201800749  0.72
2018 Kim T, McCarver S, Lee C, MacMillan DW. Sulfonamidation of Aryl and Heteroaryl Halides via Photosensitized Nickel Catalysis. Angewandte Chemie (International Ed. in English). PMID 29424956 DOI: 10.1002/anie.201800699  0.64
2018 Nacsa ED, MacMillan DWC. Spin-Center Shift-Enabled Direct Enantioselective a-Benzylation of Aldehydes with Alcohols. Journal of the American Chemical Society. PMID 29400958 DOI: 10.1021/jacs.7b12768  0.76
2018 Bloom S, Liu C, Kölmel DK, Qiao JX, Zhang Y, Poss MA, Ewing WR, MacMillan DWC. Decarboxylative alkylation for site-selective bioconjugation of native proteins via oxidation potentials. Nature Chemistry. 10: 205-211. PMID 29359756 DOI: 10.1038/nchem.2888  0.72
2017 Jamison CR, Badillo JJ, Lipshultz JM, Comito RJ, MacMillan DWC. Catalyst-controlled oligomerization for the collective synthesis of polypyrroloindoline natural products. Nature Chemistry. 9: 1165-1169. PMID 29168485 DOI: 10.1038/nchem.2825  0.88
2017 Loh YY, Nagao K, Hoover AJ, Hesk D, Rivera NR, Colletti SL, Davies IW, MacMillan DWC. Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds. Science (New York, N.Y.). PMID 29123019 DOI: 10.1126/science.aap9674  0.68
2017 Capacci AG, Malinowski JT, McAlpine NJ, Kuhne J, MacMillan DWC. Direct, enantioselective α-alkylation of aldehydes using simple olefins. Nature Chemistry. 9: 1073-1077. PMID 29064486 DOI: 10.1038/nchem.2797  0.76
2017 Zhang X, MacMillan DWC. Direct Aldehyde C-H Arylation and Alkylation via the Combination of Nickel, HAT, and Photoredox Catalysis. Journal of the American Chemical Society. PMID 28780856 DOI: 10.1021/jacs.7b07078  1
2017 Le CC, Wismer MK, Shi ZC, Zhang R, Conway DV, Li G, Vachal P, Davies IW, MacMillan DWC. A General Small-Scale Reactor To Enable Standardization and Acceleration of Photocatalytic Reactions. Acs Central Science. 3: 647-653. PMID 28691077 DOI: 10.1021/acscentsci.7b00159  0.8
2017 Le C, Liang Y, Evans RW, Li X, MacMillan DWC. Selective sp(3) C-H alkylation via polarity-match-based cross-coupling. Nature. PMID 28636596 DOI: 10.1038/nature22813  0.96
2017 Welin ER, Le C, Arias-Rotondo DM, McCusker JK, MacMillan DW. Photosensitized, energy transfer-mediated organometallic catalysis through electronically excited nickel(II). Science (New York, N.Y.). 355: 380-385. PMID 28126814 DOI: 10.1126/science.aal2490  0.96
2016 McCarver SJ, Qiao JX, Carpenter J, Borzilleri RM, Poss MA, Eastgate MD, Miller M, MacMillan DW. Decarboxylative Peptide Macrocyclization through Photoredox Catalysis. Angewandte Chemie (International Ed. in English). PMID 27860140 DOI: 10.1002/anie.201608207  0.76
2016 Zhang X, MacMillan DW. Alcohols as Latent Coupling Fragments for Metallaphotoredox Catalysis: sp3-sp2 Cross-Coupling of Oxalates with Aryl Halides. Journal of the American Chemical Society. PMID 27718570 DOI: 10.1021/jacs.6b09533  1
2016 Johnston CP, Smith RT, Allmendinger S, MacMillan DW. Metallaphotoredox-catalysed sp(3)-sp(3) cross-coupling of carboxylic acids with alkyl halides. Nature. 536: 322-5. PMID 27535536 DOI: 10.1038/nature19056  0.32
2016 Shaw MH, Twilton J, MacMillan DW. Photoredox Catalysis in Organic Chemistry. The Journal of Organic Chemistry. PMID 27477076 DOI: 10.1021/acs.joc.6b01449  0.68
2016 Corcoran EB, Pirnot MT, Lin S, Dreher SD, DiRocco DA, Davies IW, Buchwald SL, MacMillan DW. Aryl amination using ligand-free Ni(II) salts and photoredox catalysis. Science (New York, N.Y.). 353: 279-83. PMID 27338703 DOI: 10.1126/science.aag0209  0.68
2016 Zhang P, Le CC, MacMillan DW. Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross-Electrophile Coupling. Journal of the American Chemical Society. PMID 27263662 DOI: 10.1021/jacs.6b04818  0.8
2016 Shaw MH, Shurtleff VW, Terrett JA, Cuthbertson JD, MacMillan DW. Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles. Science (New York, N.Y.). PMID 27127237 DOI: 10.1126/science.aaf6635  1
2016 Zuo Z, Cong H, Li W, Choi J, Fu GC, MacMillan DW. Enantioselective Decarboxylative Arylation of α-Amino Acids via the Merger of Photoredox and Nickel Catalysis. Journal of the American Chemical Society. PMID 26849354 DOI: 10.1021/jacs.5b13211  1
2016 Nawrat CC, Jamison CR, Slutskyy Y, MacMillan DW, Overman LE. Correction to "Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling". Journal of the American Chemical Society. PMID 26820773 DOI: 10.1021/jacs.6b00456  0.92
2016 Liu C, Oblak EZ, Vander Wal MN, Dilger AK, Almstead DK, MacMillan DW. Oxy-Allyl Cation Catalysis: An Enantioselective Electrophilic Activation Mode. Journal of the American Chemical Society. PMID 26797012 DOI: 10.1021/jacs.5b13041  1
2015 Le CC, MacMillan DW. Fragment Couplings via CO2 Extrusion-Recombination: Expansion of a Classic Bond-Forming Strategy via Metallaphotoredox. Journal of the American Chemical Society. 137: 11938-41. PMID 26333771 DOI: 10.1021/jacs.5b08304  0.8
2015 Nawrat CC, Jamison CR, Slutskyy Y, MacMillan DW, Overman LE. Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling. Journal of the American Chemical Society. 137: 11270-3. PMID 26322524 DOI: 10.1021/jacs.5b07678  1
2015 Jeffrey JL, Terrett JA, MacMillan DW. O-H hydrogen bonding promotes H-atom transfer from α C-H bonds for C-alkylation of alcohols. Science (New York, N.Y.). 349: 1532-6. PMID 26316601 DOI: 10.1126/science.aac8555  0.72
2015 Jin J, MacMillan DW. Alcohols as alkylating agents in heteroarene C-H functionalization. Nature. 525: 87-90. PMID 26308895 DOI: 10.1038/nature14885  1
2015 Terrett JA, Cuthbertson JD, Shurtleff VW, MacMillan DW. Switching on elusive organometallic mechanisms with photoredox catalysis. Nature. 524: 330-4. PMID 26266976 DOI: 10.1038/nature14875  0.88
2015 Welin ER, Warkentin AA, Conrad JC, MacMillan DW. Enantioselective α-Alkylation of Aldehydes by Photoredox Organocatalysis: Rapid Access to Pharmacophore Fragments from β-Cyanoaldehydes. Angewandte Chemie (International Ed. in English). 54: 9668-72. PMID 26130043 DOI: 10.1002/anie.201503789  1
2015 Jeffrey JL, Petronijevi? FR, MacMillan DW. Selective Radical-Radical Cross-Couplings: Design of a Formal β-Mannich Reaction. Journal of the American Chemical Society. 137: 8404-7. PMID 26075347 DOI: 10.1021/jacs.5b05376  0.84
2015 Chu L, Lipshultz JM, MacMillan DW. Merging Photoredox and Nickel Catalysis: The Direct Synthesis of Ketones by the Decarboxylative Arylation of α-Oxo Acids. Angewandte Chemie (International Ed. in English). 54: 7929-33. PMID 26014029 DOI: 10.1002/anie.201501908  0.8
2015 Ventre S, Petronijevic FR, MacMillan DW. Decarboxylative Fluorination of Aliphatic Carboxylic Acids via Photoredox Catalysis. Journal of the American Chemical Society. 137: 5654-7. PMID 25881929 DOI: 10.1021/jacs.5b02244  0.36
2015 Cuthbertson JD, MacMillan DWC. The direct arylation of allylic sp3 C-H bonds via organic and photoredox catalysis Nature. 519: 74-77. PMID 25739630 DOI: 10.1038/nature14255  0.88
2015 Noble A, McCarver SJ, MacMillan DW. Merging photoredox and nickel catalysis: decarboxylative cross-coupling of carboxylic acids with vinyl halides. Journal of the American Chemical Society. 137: 624-7. PMID 25521443 DOI: 10.1021/ja511913h  1
2015 Jin J, MacMillan DW. Direct α-arylation of ethers through the combination of photoredox-mediated C-H functionalization and the Minisci reaction. Angewandte Chemie (International Ed. in English). 54: 1565-9. PMID 25470570 DOI: 10.1002/anie.201410432  1
2015 Jeffrey JL, Petronijevi? FR, Macmillan DWC. Selective Radical-Radical Cross-Couplings: Design of a Formal β-Mannich Reaction Journal of the American Chemical Society. 137: 8404-8407. DOI: 10.1021/jacs.5b05376  1
2015 Ventre S, Petronijevic FR, Macmillan DWC. Decarboxylative fluorination of aliphatic carboxylic acids via photoredox catalysis Journal of the American Chemical Society. 137: 5654-5657. DOI: 10.1021/jacs.5b02244  1
2015 Chu L, Lipshultz JM, Macmillan DWC. Merging Photoredox and Nickel Catalysis: The Direct Synthesis of Ketones by the Decarboxylative Arylation of α-Oxo Acids Angewandte Chemie - International Edition. 54: 7929-7933. DOI: 10.1002/anie.201501908  0.8
2015 Jin J, MacMillan DWC. Direct α-arylation of ethers through the combination of photoredox-mediated C-H functionalization and the minisci reaction Angewandte Chemie - International Edition. 54: 1565-1569. DOI: 10.1002/anie.201410432  1
2014 Prier CK, MacMillan DW. Amine α-heteroarylation via photoredox catalysis: a homolytic aromatic substitution pathway. Chemical Science (Royal Society of Chemistry : 2010). 5: 4173-4178. PMID 26236461 DOI: 10.1039/C4SC02155J  1
2014 Hager D, MacMillan DW. Activation of C-H bonds via the merger of photoredox and organocatalysis: a coupling of benzylic ethers with Schiff bases. Journal of the American Chemical Society. 136: 16986-9. PMID 25457231 DOI: 10.1021/ja5102695  0.4
2014 Chu L, Ohta C, Zuo Z, MacMillan DW. Carboxylic acids as a traceless activation group for conjugate additions: a three-step synthesis of (±)-pregabalin. Journal of the American Chemical Society. 136: 10886-9. PMID 25032785 DOI: 10.1021/ja505964r  1
2014 Noble A, MacMillan DW. Photoredox α-vinylation of α-amino acids and N-aryl amines. Journal of the American Chemical Society. 136: 11602-5. PMID 25026314 DOI: 10.1021/ja506094d  1
2014 Zuo Z, Ahneman DT, Chu L, Terrett JA, Doyle AG, MacMillan DW. Dual catalysis. Merging photoredox with nickel catalysis: coupling of α-carboxyl sp³-carbons with aryl halides. Science (New York, N.Y.). 345: 437-40. PMID 24903563 DOI: 10.1126/science.1255525  1
2014 Terrett JA, Clift MD, MacMillan DW. Direct β-alkylation of aldehydes via photoredox organocatalysis. Journal of the American Chemical Society. 136: 6858-61. PMID 24754456 DOI: 10.1021/ja502639e  0.64
2014 Zuo Z, MacMillan DW. Decarboxylative arylation of α-amino acids via photoredox catalysis: a one-step conversion of biomass to drug pharmacophore. Journal of the American Chemical Society. 136: 5257-60. PMID 24712922 DOI: 10.1021/ja501621q  1
2014 Peifer M, Berger R, Shurtleff VW, Conrad JC, MacMillan DW. A general and enantioselective approach to pentoses: a rapid synthesis of PSI-6130, the nucleoside core of sofosbuvir. Journal of the American Chemical Society. 136: 5900-3. PMID 24670208 DOI: 10.1021/ja502205q  1
2014 Qvortrup K, Rankic DA, MacMillan DWC. A general strategy for organocatalytic activation of c-h bonds via photoredox catalysis: Direct arylation of benzylic ethers Journal of the American Chemical Society. 136: 626-629. PMID 24341523 DOI: 10.1021/ja411596q  0.68
2014 Prier CK, MacMillan DWC. Amine α-heteroarylation via photoredox catalysis: A homolytic aromatic substitution pathway Chemical Science. 5: 4173-4178. DOI: 10.1039/c4sc02155j  1
2014 Hager D, Macmillan DWC. Activation of C-H bonds via the merger of photoredox and organocatalysis: A coupling of benzylic ethers with schiff bases Journal of the American Chemical Society. 136: 16986-16989. DOI: 10.1021/ja5102695  0.4
2014 Chu L, Ohta C, Zuo Z, MacMillan DWC. Carboxylic acids as A traceless activation group for conjugate additions: A three-step synthesis of (±)-pregabalin Journal of the American Chemical Society. 136: 10886-10889. DOI: 10.1021/ja505964r  1
2014 Terrett JA, Clift MD, MaCmillan DWC. Direct β-alkylation of aldehydes via photoredox organocatalysis Journal of the American Chemical Society. 136: 6858-6861. DOI: 10.1021/ja502639e  0.64
2014 Zuo Z, Macmillan DWC. Decarboxylative arylation of α-Amino acids via photoredox catalysis: A one-step conversion of biomass to drug pharmacophore Journal of the American Chemical Society. 136: 5257-5260. DOI: 10.1021/ja501621q  1
2013 Petronijevi? FR, Nappi M, MacMillan DWC. Direct β-functionalization of cyclic ketones with aryl ketones via the merger of photoredox and organocatalysis Journal of the American Chemical Society. 135: 18323-18326. PMID 24237366 DOI: 10.1021/ja410478a  0.76
2013 Evans RW, Zbieg JR, Zhu S, Li W, MacMillan DW. Simple catalytic mechanism for the direct coupling of α-carbonyls with functionalized amines: a one-step synthesis of Plavix. Journal of the American Chemical Society. 135: 16074-7. PMID 24107144 DOI: 10.1021/ja4096472  1
2013 Laforteza BN, Pickworth M, MacMillan DWC. Enantioselective total synthesis of (-)-minovincine in nine chemical steps: An approach to ketone activation in cascade catalysis Angewandte Chemie - International Edition. 52: 11269-11272. PMID 24000234 DOI: 10.1002/anie.201305171  1
2013 Stevens JM, MacMillan DWC. Enantioselective α-alkenylation of aldehydes with boronic acids via the synergistic combination of copper(II) and amine catalysis Journal of the American Chemical Society. 135: 11756-11759. PMID 23889497 DOI: 10.1021/ja406356c  1
2013 Cecere G, König CM, Alleva JL, MacMillan DW. Enantioselective direct α-amination of aldehydes via a photoredox mechanism: a strategy for asymmetric amine fragment coupling. Journal of the American Chemical Society. 135: 11521-4. PMID 23869694 DOI: 10.1021/ja406181e  1
2013 Comito RJ, Finelli FG, Macmillan DWC. Enantioselective intramolecular aldehyde α-alkylation with simple olefins: Direct access to homo-ene products Journal of the American Chemical Society. 135: 9358-9361. PMID 23745728 DOI: 10.1021/ja4047312  1
2013 Horning BD, MacMillan DWC. Nine-step enantioselective total synthesis of (-)-vincorine Journal of the American Chemical Society. 135: 6442-6445. PMID 23586842 DOI: 10.1021/ja402933s  1
2013 Pirnot MT, Rankic DA, Martin DB, MacMillan DW. Photoredox activation for the direct β-arylation of ketones and aldehydes. Science (New York, N.Y.). 339: 1593-6. PMID 23539600 DOI: 10.1126/science.1232993  1
2013 Prier CK, Rankic DA, MacMillan DW. Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis. Chemical Reviews. 113: 5322-63. PMID 23509883 DOI: 10.1021/cr300503r  1
2013 Vander Wal MN, Dilger AK, Macmillan DWC. Development of a generic activation mode: Nucleophilic α-substitution of ketones via oxy-allyl cations Chemical Science. 4: 3075-3079. DOI: 10.1039/c3sc51266e  1
2013 MacMillan DWC, Rendler S. Enantioselective Organo-SOMO Catalysis: A Novel Activation Mode for Asymmetric Synthesis Asymmetric Synthesis Ii: More Methods and Applications. 87-94. DOI: 10.1002/9783527652235.ch12  0.92
2012 Jui NT, Garber JA, Finelli FG, MacMillan DW. Enantioselective organo-SOMO cycloadditions: a catalytic approach to complex pyrrolidines from olefins and aldehydes. Journal of the American Chemical Society. 134: 11400-3. PMID 22764834 DOI: 10.1021/ja305076b  1
2012 Zhu S, MacMillan DW. Enantioselective copper-catalyzed construction of aryl pyrroloindolines via an arylation-cyclization cascade. Journal of the American Chemical Society. 134: 10815-8. PMID 22716914 DOI: 10.1021/ja305100g  1
2012 Skucas E, MacMillan DWC. Enantioselective α-vinylation of aldehydes via the synergistic combination of copper and amine catalysis Journal of the American Chemical Society. 134: 9090-9093. PMID 22616631 DOI: 10.1021/ja303116v  0.44
2012 Allen AE, Macmillan DW. Synergistic Catalysis: A Powerful Synthetic Strategy for New Reaction Development. Chemical Science (Royal Society of Chemistry : 2010). 2012: 633-658. PMID 22518271 DOI: 10.1039/C2SC00907B  1
2012 Simonovich SP, Van Humbeck JF, Macmillan DW. A general approach to the enantioselective α-oxidation of aldehydes via synergistic catalysis. Chemical Science (Royal Society of Chemistry : 2010). 3: 58-61. PMID 22308217 DOI: 10.1039/c1sc00556a  0.96
2012 Graham TH, Horning BD, MacMillan DWC. The preparation of (2r,5s)-2-t-butyl-3,5-dimethylimidazolidin-4-one Organic Syntheses. 88: 42-53. DOI: 10.15227/orgsyn.088.0042  1
2012 MacMillan D, Eagling RD, Thomson J, Ross P. Chemical Science - The best new journal Chemical Science. 3: 15-19. DOI: 10.1039/c1sc90051j  1
2012 Simonovich SP, Van Humbeck JF, MacMillan DWC. A general approach to the enantioselective α-oxidation of aldehydes via synergistic catalysis Chemical Science. 3: 58-61. DOI: 10.1039/c1sc00556a  1
2011 Pham PV, Ashton K, Macmillan DW. The Intramolecular Asymmetric Allylation of Aldehydes via Organo-SOMO Catalysis: A Novel Approach to Ring Construction. Chemical Science (Royal Society of Chemistry : 2010). 2: 1470-1473. PMID 23087809 DOI: 10.1039/C1SC00176K  0.92
2011 Knowles RR, Carpenter J, Blakey SB, Kayano A, Mangion IK, Sinz CJ, Macmillan DW. Total synthesis of diazonamide A. Chemical Science (Royal Society of Chemistry : 2010). 2011: 308-311. PMID 22860227 DOI: 10.1039/C0SC00577K  1
2011 Nagib DA, Macmillan DWC. Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis Nature. 480: 224-228. PMID 22158245 DOI: 10.1038/nature10647  1
2011 McNally A, Prier CK, MacMillan DW. Discovery of an α-amino C-H arylation reaction using the strategy of accelerated serendipity. Science (New York, N.Y.). 334: 1114-7. PMID 22116882 DOI: 10.1126/science.1213920  1
2011 Harvey JS, Simonovich SP, Jamison CR, MacMillan DW. Enantioselective α-arylation of carbonyls via Cu(I)-bisoxazoline catalysis. Journal of the American Chemical Society. 133: 13782-5. PMID 21848265 DOI: 10.1021/ja206050b  1
2011 Jones SB, Simmons B, Mastracchio A, MacMillan DWC. Collective synthesis of natural products by means of organocascade catalysis Nature. 475: 183-188. PMID 21753848 DOI: 10.1038/nature10232  1
2011 Pham PV, Nagib DA, MacMillan DWC. Photoredox catalysis: A mild, operationally simple approach to the synthesis of α-trifluoromethyl carbonyl compounds Angewandte Chemie - International Edition. 50: 6119-6122. PMID 21604347 DOI: 10.1002/anie.201101861  1
2011 Allen AE, MacMillan DWC. Enantioselective α-arylation of aldehydes via the productive merger of iodonium salts and organocatalysis Journal of the American Chemical Society. 133: 4260-4263. PMID 21388207 DOI: 10.1021/ja2008906  1
2011 Kwiatkowski P, Beeson TD, Conrad JC, MacMillan DW. Enantioselective organocatalytic α-fluorination of cyclic ketones. Journal of the American Chemical Society. 133: 1738-41. PMID 21247133 DOI: 10.1021/ja111163u  1
2011 Pham PV, Ashton K, MacMillan DWC. The intramolecular asymmetric allylation of aldehydes via organo-SOMO catalysis: A novel approach to ring construction Chemical Science. 2: 1470-1473. DOI: 10.1039/c1sc00176k  1
2010 Reiter M, Torssell S, Lee S, Macmillan DW. The organocatalytic three-step total synthesis of (+)-frondosin B. Chemical Science (Royal Society of Chemistry : 2010). 1: 37-42. PMID 22299067 DOI: 10.1039/C0SC00204F  1
2010 Jacobsen EN, MacMillan DW. Organocatalysis. Proceedings of the National Academy of Sciences of the United States of America. 107: 20618-9. PMID 21119011 DOI: 10.1073/pnas.1016087107  1
2010 Mastracchio A, Warkentin AA, Walji AM, MacMillan DW. Direct and enantioselective {alpha}-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis. Proceedings of the National Academy of Sciences of the United States of America. 107: 20648-51. PMID 20921367 DOI: 10.1073/pnas.1002845107  0.92
2010 Shih HW, Vander Wal MN, Grange RL, MacMillan DWC. Enantioselective α-benzylation of aldehydes via photoredox organocatalysis Journal of the American Chemical Society. 132: 13600-13603. PMID 20831195 DOI: 10.1021/ja106593m  1
2010 Devery JJ, Conrad JC, MacMillan DW, Flowers RA. Mechanistic complexity in organo-SOMO activation. Angewandte Chemie (International Ed. in English). 49: 6106-10. PMID 20632343 DOI: 10.1002/anie.201001673  1
2010 Van Humbeck JF, Simonovich SP, Knowles RR, MacMillan DW. Concerning the mechanism of the FeCl3-catalyzed alpha-oxyamination of aldehydes: evidence for a non-SOMO activation pathway. Journal of the American Chemical Society. 132: 10012-4. PMID 20608675 DOI: 10.1021/ja1043006  1
2010 Jui NT, Lee ECY, MacMillan DWC. Enantioselective organo-SOMO cascade cycloadditions: A rapid approach to molecular complexity from simple aldehydes and olefins Journal of the American Chemical Society. 132: 10015-10017. PMID 20593858 DOI: 10.1021/ja104313x  1
2010 Um JM, Gutierrez O, Schoenebeck F, Houk KN, Macmillan DWC. Nature of intermediates in organo-somo catalysis of α-arylation of aldehydes Journal of the American Chemical Society. 132: 6001-6005. PMID 20387888 DOI: 10.1021/ja9063074  0.56
2010 Rendler S, MacMillan DWC. Enantioselective polyene cyclization via organo-SOMO catalysis Journal of the American Chemical Society. 132: 5027-5029. PMID 20334384 DOI: 10.1021/ja100185p  0.92
2010 Allen AE, MacMillan DWC. The productive merger of iodonium salts and organocatalysis: A non-photolytic approach to the enantioselective α-trifluoromethylation of aldehydes Journal of the American Chemical Society. 132: 4986-4987. PMID 20297822 DOI: 10.1021/ja100748y  1
2010 Mastracchio A, Warkentin AA, Walji AM, MacMillan DWC. Direct and enantioselective a-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis Proceedings of the National Academy of Sciences of the United States of America. 107: 20648-20651. DOI: 10.1073/pnas.1002845107  1
2010 Reiter M, Torssell S, Lee S, MacMillan DWC. The organocatalytic three-step total synthesis of (+)-frondosin B Chemical Science. 1: 37-42. DOI: 10.1039/c0sc00204f  1
2010 MacMillan D, Eagling R. Introducing Chemical Science - Recognition starts here Chemical Science. 1: 11-12. DOI: 10.1039/c005351c  1
2010 Watson AJB, MacMillan DWC, Wang Y, Deng L, Shirakawa S, Maruoka K. Asymmetric Organocatalysis Catalytic Asymmetric Synthesis: Third Edition. 37-117. DOI: 10.1002/9780470584248.ch2  1
2010 Nicewicz DA, MacMillan DWC. Merging photoredox catalysis with organocatalysis: The direct asymmetric alkylation of aldehydes Chemtracts. 23: 73-76.  0.88
2009 Borths CJ, Carrera DE, MacMillan DW. Development of a general, enantioselective organocatalytic Mukaiyama-Michael reaction with α,β-unsaturated aldehydes. Tetrahedron. 65: 6746-6753. PMID 25214677 DOI: 10.1016/j.tet.2009.06.066  0.48
2009 Jones SB, Simmons B, MacMillan DWC. Nine-step enantioselective total synthesis of (+)-minfiensine Journal of the American Chemical Society. 131: 13606-13607. PMID 19725517 DOI: 10.1021/ja906472m  1
2009 Nagib DA, Scott ME, MacMillan DWC. Enantioselective α-trifluoromethylation of aldehydes via photoredox organocatalysis Journal of the American Chemical Society. 131: 10875-10877. PMID 19722670 DOI: 10.1021/ja9053338  1
2009 Conrad JC, Kong J, Laforteza BN, MacMillan DW. Enantioselective alpha-arylation of aldehydes via organo-SOMO catalysis. An ortho-selective arylation reaction based on an open-shell pathway. Journal of the American Chemical Society. 131: 11640-1. PMID 19639997 DOI: 10.1021/ja9026902  1
2009 Wilson JE, Casarez AD, MacMillan DW. Enantioselective aldehyde alpha-nitroalkylation via oxidative organocatalysis. Journal of the American Chemical Society. 131: 11332-4. PMID 19627154 DOI: 10.1021/ja904504j  1
2009 Amatore M, Beeson TD, Brown SP, MacMillan DW. Enantioselective linchpin catalysis by SOMO catalysis: an approach to the asymmetric alpha-chlorination of aldehydes and terminal epoxide formation. Angewandte Chemie (International Ed. in English). 48: 5121-4. PMID 19526479 DOI: 10.1002/anie.200901855  1
2009 Simmons B, Walji AM, MacMillan DWC. Cycle-specific organocascade catalysis: Application to olefin hydroamination, hydro-oxidation, and amino-oxidation, and to natural product synthesis Angewandte Chemie - International Edition. 48: 4349-4353. PMID 19434637 DOI: 10.1002/anie.200900220  1
2009 Brimble M, St Clair Black D, Ciufolini MA, Fukuyama T, Fürstner A, Grigg R, Hiemstra H, MacMillan DWC, Shibasaki M, Tietze L, Wipf P. Editorial Advisory Board Members Progress in Heterocyclic Chemistry 2008-2009 Progress in Heterocyclic Chemistry. 21: xii. DOI: 10.1016/S0959-6380(09)70027-3  1
2009 Borths CJ, Carrera DE, MacMillan DWC. Development of a general, enantioselective organocatalytic Mukaiyama-Michael reaction with α,β-unsaturated aldehydes Tetrahedron. 65: 6746-6753. DOI: 10.1016/j.tet.2009.06.066  0.48
2009 Paras NA, Simmons B, MacMillan DWC. A process for the rapid removal of dialkylamino-substituents from aromatic rings. Application to the expedient synthesis of (R)-tolterodine Tetrahedron. 65: 3232-3238. DOI: 10.1016/j.tet.2008.12.054  1
2008 Graham TH, Jones CM, Jui NT, MacMillan DW. Enantioselective organo-singly occupied molecular orbital catalysis: the carbo-oxidation of styrenes. Journal of the American Chemical Society. 130: 16494-5. PMID 19049447 DOI: 10.1021/ja8075633  1
2008 Nicewicz DA, MacMillan DW. Merging photoredox catalysis with organocatalysis: the direct asymmetric alkylation of aldehydes. Science (New York, N.Y.). 322: 77-80. PMID 18772399 DOI: 10.1126/science.1161976  1
2008 Carpenter J, Northrup AB, Chung D, Wiener JJM, Kim SG, MacMillan DWC. Total synthesis and structural revision of callipeltoside C Angewandte Chemie - International Edition. 47: 3568-3572. PMID 18381726 DOI: 10.1002/anie.200800086  1
2008 Kim H, MacMillan DWC. Enantioselective organo-SOMO catalysis: The α-vinylation of aldehydes Journal of the American Chemical Society. 130: 398-399. PMID 18095690 DOI: 10.1021/ja077212h  0.96
2008 Lee S, MacMillan DWC. Organocatalytic vinyl and friedel-crafts alkylations with trifluoroborate salts Chemtracts. 21: 306-307. DOI: 10.1021/ja0767480  1
2007 Ouellet SG, Walji AM, Macmillan DWC. Enantioselective organocatalytic transfer hydrogenation reactions using Hantzsch esters Accounts of Chemical Research. 40: 1327-1339. PMID 18085748 DOI: 10.1021/ar7001864  1
2007 Lee S, MacMillan DW. Organocatalytic vinyl and Friedel-Crafts alkylations with trifluoroborate salts. Journal of the American Chemical Society. 129: 15438-9. PMID 18031044 DOI: 10.1021/ja0767480  1
2007 Jang HY, Hong JB, MacMillan DWC. Enantioselective organocatalytic singly occupied molecular orbital activation: The enantioselective α-enolation of aldehydes Journal of the American Chemical Society. 129: 7004-7005. PMID 17497866 DOI: 10.1021/ja0719428  1
2007 Beeson TD, Mastracchio A, Hong JB, Ashton K, MacMillan DWC. Enantioselective organocatalysis using SOMO activation Science. 316: 582-585. PMID 17395791 DOI: 10.1126/science.  1
2007 Walji AM, MacMillan DWC. Strategies to bypass the taxol problem. Enantioselective cascade catalysis, a new approach for the efficient construction of molecular complexity Synlett. 1477-1489. DOI: 10.1055/s-2007-980382  1
2007 Lelais G, MacMillan DWC. Iminium Catalysis Enantioselective Organocatalysis: Reactions and Experimental Procedures. 95-120. DOI: 10.1002/9783527610945.ch3  0.72
2006 Tuttle JB, Ouellet SG, MacMillan DWC. Organocatalytic transfer hydrogenation of cyclic enones Journal of the American Chemical Society. 128: 12662-12663. PMID 17002356 DOI: 10.1021/ja0653066  1
2006 Chen YK, Yoshida M, MacMillan DWC. Enantioselective organocatalytic amine conjugate addition Journal of the American Chemical Society. 128: 9328-9329. PMID 16848457 DOI: 10.1021/ja063267s  1
2006 Storer RI, Carrera DE, Ni Y, MacMillan DWC. Enantioselective organocatalytic reductive amination Journal of the American Chemical Society. 128: 84-86. PMID 16390133 DOI: 10.1021/ja057222n  0.48
2006 Lee S, MacMillan DWC. Enantioselective organocatalytic epoxidation using hypervalent iodine reagents Tetrahedron. 62: 11413-11424. DOI: 10.1016/j.tet.2006.07.055  1
2006 Lelais G, Macmillan DWC. History and Perspective of Chiral Organic Catalysts New Frontiers in Asymmetric Catalysis. 313-358. DOI: 10.1002/0470098007.ch11  0.72
2006 Lelais G, MacMillan DWC. Modern strategies in organic catalysis: The advent and development of iminium activation Aldrichimica Acta. 39: 79-87.  0.72
2005 Huang Y, Walji AM, Larsen CH, MacMillan DW. Enantioselective organo-cascade catalysis. Journal of the American Chemical Society. 127: 15051-3. PMID 16248643 DOI: 10.1021/ja055545d  1
2005 Wilson RM, Jen WS, MacMillan DWC. Enantioselective organocatalytic intramolecular Diels-Alder reactions. The asymmetric synthesis of solanapyrone D Journal of the American Chemical Society. 127: 11616-11617. PMID 16104734 DOI: 10.1021/ja054008q  1
2005 Beeson TD, MacMillan DWC. Enantioselective organocatalytic α-fluorination of aldehydes Journal of the American Chemical Society. 127: 8826-8828. PMID 15954790 DOI: 10.1021/ja051805f  1
2005 Mangion IK, MacMillan DWC. Total synthesis of brasoside and littoralisone Journal of the American Chemical Society. 127: 3696-3697. PMID 15771494 DOI: 10.1021/ja050064f  0.68
2005 Kunz RK, MacMillan DWC. Enantioselective organocatalytic cyclopropanations. The identification of a new class of iminium catalyst based upon directed electrostatic activation Journal of the American Chemical Society. 127: 3240-3241. PMID 15755116 DOI: 10.1021/ja042774b  1
2005 Ouellet SG, Tuttle JB, MacMillan DWC. Enantioselective organocatalytic hydride reduction Journal of the American Chemical Society. 127: 32-33. PMID 15631434 DOI: 10.1021/ja043834g  1
2004 Mangion IK, Northrup AB, MacMillan DWC. The importance of iminium geometry control in enamine catalysis: Identification of a new catalyst architecture for aldehyde-aldehyde couplings Angewandte Chemie - International Edition. 43: 6722-6724. PMID 15593153 DOI: 10.1002/anie.200461851  1
2004 Northrup AB, MacMillan DWC. Two-step synthesis of carbohydrates by selective aldol reactions Science. 305: 1752-1755. PMID 15308765 DOI: 10.1126/science.1101710  1
2004 Northrup AB, Mangion IK, Hettche F, MacMillan DW. Enantioselective organocatalytic direct aldol reactions of alpha-oxyaldehydes: step one in a two-step synthesis of carbohydrates. Angewandte Chemie (International Ed. in English). 43: 2152-4. PMID 15083470 DOI: 10.1002/anie.200453716  0.72
2004 Austin JF, Kim SG, Sinz CJ, Xiao WJ, MacMillan DW. Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition-cyclization strategy: synthesis of (-)-flustramine B. Proceedings of the National Academy of Sciences of the United States of America. 101: 5482-7. PMID 15067109 DOI: 10.1073/pnas.0308177101  1
2004 Brochu MP, Brown SP, MacMillan DW. Direct and enantioselective organocatalytic alpha-chlorination of aldehydes. Journal of the American Chemical Society. 126: 4108-9. PMID 15053591 DOI: 10.1021/ja049562z  1
2004 Ian Storer R, MacMillan DWC. Enantioselective organocatalytic aldehyde-aldehyde cross-aldol couplings. The broad utility of α-thioacetal aldehydes Tetrahedron. 60: 7705-7714. DOI: 10.1016/j.tet.2004.04.089  0.48
2004 Northrup AB, Mangion IK, Hettche F, MacMillan DWC. Enantioselective organocatalytic direct aldol reactions of α-oxyaldehydes: Step one in a two-step synthesis of carbohydrates Angewandte Chemie - International Edition. 43: 2152-2154. DOI: 10.1002/anie.200453716  1
2003 Brown SP, Brochu MP, Sinz CJ, MacMillan DW. The direct and enantioselective organocatalytic alpha-oxidation of aldehydes. Journal of the American Chemical Society. 125: 10808-9. PMID 12952459 DOI: 10.1021/ja037096s  1
2003 Blakey SB, MacMillan DW. The first Suzuki cross-couplings of aryltrimethylammonium salts. Journal of the American Chemical Society. 125: 6046-7. PMID 12785821 DOI: 10.1021/ja034908b  0.68
2003 Brown SP, Goodwin NC, MacMillan DW. The first enantioselective organocatalytic Mukaiyama-Michael reaction: a direct method for the synthesis of enantioenriched gamma-butenolide architecture. Journal of the American Chemical Society. 125: 1192-4. PMID 12553821 DOI: 10.1021/ja029095q  1
2002 Lambert TH, MacMillan DW. Development of a new Lewis acid-catalyzed [3,3]-sigmatropic rearrangement: the allenoate-Claisen rearrangement. Journal of the American Chemical Society. 124: 13646-7. PMID 12431073 DOI: 10.1021/ja028090q  1
2002 Evans DA, Wu J, Masse CE, MacMillan DW. A general method for the enantioselective synthesis of pantolactone derivatives. Organic Letters. 4: 3379-82. PMID 12323023 DOI: 10.1021/ol026489d  1
2002 Paras NA, MacMillan DW. The enantioselective organocatalytic 1,4-addition of electron-rich benzenes to alpha,beta-unsaturated aldehydes. Journal of the American Chemical Society. 124: 7894-5. PMID 12095321 DOI: 10.1021/ja025981p  1
2002 Northrup AB, MacMillan DW. The first direct and enantioselective cross-aldol reaction of aldehydes. Journal of the American Chemical Society. 124: 6798-9. PMID 12059180 DOI: 10.1021/ja0262378  1
2002 Northrup AB, MacMillan DW. The first general enantioselective catalytic Diels-Alder reaction with simple alpha,beta-unsaturated ketones. Journal of the American Chemical Society. 124: 2458-60. PMID 11890793 DOI: 10.1021/ja017641u  1
2002 Austin JF, MacMillan DW. Enantioselective organocatalytic indole alkylations. Design of a new and highly effective chiral amine for iminium catalysis. Journal of the American Chemical Society. 124: 1172-3. PMID 11841277 DOI: 10.1021/ja017255c  1
2001 MacMillan DW, Overman LE, Pennington LD. A general strategy for the synthesis of cladiellin diterpenes: enantioselective total syntheses of 6-acetoxycladiell-7(16),11-dien-3-ol (deacetoxyalcyonin acetate), cladiell-11-ene-3,6,7-triol, sclerophytin A, and the initially purported structure of sclerophytin A. Journal of the American Chemical Society. 123: 9033-44. PMID 11552811 DOI: 10.1021/ja016351a  1
2001 Paras NA, MacMillan DW. New strategies in organic catalysis: the first enantioselective organocatalytic Friedel-Crafts alkylation. Journal of the American Chemical Society. 123: 4370-1. PMID 11457218  1
2001 Yoon TP, MacMillan DW. Enantioselective Claisen rearrangements: development of a first generation asymmetric acyl-Claisen reaction. Journal of the American Chemical Society. 123: 2911-2. PMID 11456990 DOI: 10.1021/ja015612d  1
2001 Dong VM, MacMillan DW. Design of a new cascade reaction for the construction of complex acyclic architecture: the tandem acyl-claisen rearrangement. Journal of the American Chemical Society. 123: 2448-9. PMID 11456904 DOI: 10.1021/ja005925t  1
2001 Gallou F, MacMillan DW, Overman LE, Paquette LA, Pennington LD, Yang J. Enantioselective syntheses of authentic sclerophytin A, sclerophytin B, and cladiell-11-ene-3,6,7-triol. Organic Letters. 3: 135-7. PMID 11429857 DOI: 10.1021/ol000345m  1
2001 Cohen F, MacMillan DW, Overman LE, Romero A. Stereoselection in the Prins-pinacol synthesis of acyltetrahydrofurans. Organic Letters. 3: 1225-8. PMID 11348200 DOI: 10.1021/ol0157003  1
2000 Hanaki N, Link JT, MacMillan DW, Overman LE, Trankle WG, Wurster JA. Stereoselection in the prins-pinacol synthesis of 2,2-disubstituted 4-acyltetrahydrofurans. Enantioselective synthesis of (-)-citreoviral. Organic Letters. 2: 223-6. PMID 10814287  1
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