Gordon W. Gribble - Publications

Affiliations: 
Chemistry Dartmouth College, Hanover, NH, United States 
Area:
Organic synthesis, biologically active natural products, heterocyclic chemistry
Website:
http://www.dartmouth.edu/~chem/faculty/gwg.html

196 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Simon WM, Trujillo HA, Pelkey ET, Gribble GW, Jasinski JP. The fused heterocycle 2-benzyl-3-methyl-1-phenyl-4-phenylsulfonyl-2H,4H-pyrrolo[3,4-b]indole Acta Crystallographica Section C: Crystal Structure Communications. 56: 461-462.  0.96
2015 Mannes PZ, Onyango EO, Gribble GW. Triple Benzannulation of Naphthalene via a 1,3,6-Naphthotriyne Synthetic Equivalent. Synthesis of Dibenz[a,c]anthracene. The Journal of Organic Chemistry. 80: 11189-92. PMID 26452053 DOI: 10.1021/acs.joc.5b01972  0.96
2015 Cao M, Onyango EO, Williams CR, Royce DB, Gribble GW, Sporn MB, Liby KT. Novel Synthetic Pyridyl Analogues of CDDO-Imidazolide Are Useful New Tools in Cancer Prevention. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. PMID 26238177 DOI: 10.1016/j.phrs.2015.07.024  0.96
2015 Gribble GW. Biological Activity of Recently Discovered Halogenated Marine Natural Products. Marine Drugs. 13: 4044-136. PMID 26133553 DOI: 10.3390/md13074044  0.96
2015 Onyango EO, Kelley AR, Qian DC, Gribble GW. Syntheses of 1-Bromo-8-methylnaphthalene and 1-Bromo-5-methylnaphthalene. The Journal of Organic Chemistry. 80: 5970-2. PMID 25923236 DOI: 10.1021/acs.joc.5b00730  0.96
2015 Montgomery WL, Lopchuk JM, Gribble GW, Jasinski JP. Synthesis, crystal structures, and dft calculations of three new cyano(Phenylsulfonyl)indoles and a key synthetic precursor compound Crystals. 5: 376-393. DOI: 10.3390/cryst5030376  0.96
2015 Gribble GW. A recent survey of naturally occurring organohalogen compounds Environmental Chemistry. 12: 396-405. DOI: 10.1071/EN15002  0.96
2015 Lopchuk JM, Song M, Butler B, Gribble GW. Synthesis of Heteroaryl-Substituted Pyrroles via the 1,3-Dipolar Cycloaddition of Unsymmetrical Münchnones and Nitrovinylheterocycles Synthesis (Germany). DOI: 10.1055/s-0034-1380720  0.96
2014 Fu L, Lin QX, Liby KT, Sporn MB, Gribble GW. An efficient synthesis of methyl 2-cyano-3,12-dioxoursol-1,9-dien-28-oate (CDDU-methyl ester): analogues, biological activities, and comparison with oleanolic acid derivatives. Organic & Biomolecular Chemistry. 12: 5192-200. PMID 24915424 DOI: 10.1039/c4ob00679h  0.96
2014 Lopchuk JM, Gribble GW, Jasinski JP. Methyl 1-benzyl-5-methyl-2,4-diphenyl-1H-pyrrole-3-carboxyl-ate. Acta Crystallographica. Section E, Structure Reports Online. 70: o338-9. PMID 24765032 DOI: 10.1107/S1600536814003316  0.72
2014 Onyango EO, Fu L, Cao M, Liby KT, Sporn MB, Gribble GW. Synthesis and biological evaluation of amino acid methyl ester conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid against the production of nitric oxide (NO) Bioorganic and Medicinal Chemistry Letters. 24: 532-534. PMID 24388806 DOI: 10.1016/j.bmcl.2013.12.034  0.96
2014 Onyango EO, Fu L, Gribble GW. Synthesis of a dicyano abietane, a key intermediate for the anti-inflammatory agent TBE-31 Organic Letters. 16: 322-324. PMID 24303944 DOI: 10.1021/ol403289y  0.96
2014 Lopchuk JM, Gribble GW, Jasinski JP. Methyl 1-benzyl-5-methyl-2,4-diphenyl-1H-pyrrole-3-carboxylate Acta Crystallographica Section E: Structure Reports Online. 70: o338-o339. DOI: 10.1107/S1600536814003316  0.96
2014 Lopchuk JM, Gribble GW. Total synthesis of atorvastatin via a late-stage, regioselective 1,3-dipolar münchnone cycloaddition Tetrahedron Letters. DOI: 10.1016/j.tetlet.2014.12.104  0.96
2014 Onyango EO, Fu L, Gribble GW. Synthesis of a furano abietane cyano enone - A new scaffold for biological exploration Tetrahedron Letters. 55: 4636-4638. DOI: 10.1016/j.tetlet.2014.06.087  0.96
2014 Lopchuk JM, Gribble GW. The reaction of arynes with münchnones: Synthesis of isoindoles and azaisoindoles Tetrahedron Letters. 55: 2809-2812. DOI: 10.1016/j.tetlet.2014.03.055  0.96
2014 Gribble GW, Joule JA. Foreword Progress in Heterocyclic Chemistry. 26: xii-xiii. DOI: 10.1016/B978-0-08-100017-5.22001-3  0.96
2013 Lopchuk JM, Gribble GW, Millikan SP, Jasinski JP. Bruceolline J: 2-hy-droxy-3,3-dimethyl-2,3-di-hydro-cyclo-penta-[b]indol-1(4H)-one. Acta Crystallographica. Section E, Structure Reports Online. 69: o1351-2. PMID 24109417 DOI: 10.1107/S1600536813020527  0.72
2013 Lopchuk JM, Hughes RP, Gribble GW. What controls regiochemistry in 1,3-dipolar cycloadditions of münchnones with nitrostyrenes? Organic Letters. 15: 5218-21. PMID 24073889 DOI: 10.1021/ol402385v  0.96
2013 Lopchuk JM, Gribble GW, Jasinski JP. Bruceolline D: 3,3-dimethyl-1H,4H-cyclo-penta-[b]indol-2(3H)-one. Acta Crystallographica. Section E, Structure Reports Online. 69: o1043. PMID 24046619 DOI: 10.1107/S1600536813014955  0.72
2013 Lopchuk JM, Green IL, Badenock JC, Gribble GW. A short, protecting group-free total synthesis of bruceollines D, E, and J Organic Letters. 15: 4485-4487. PMID 23937106 DOI: 10.1021/ol402042f  0.96
2013 Fu L, Gribble GW. Efficient and scalable synthesis of bardoxolone methyl (CDDO-methyl ester) Organic Letters. 15: 1622-1625. PMID 23530743 DOI: 10.1021/ol400399x  0.96
2013 Lopchuk JM, Gribble GW, Millikan SP, Jasinski JP. Bruceolline J: 2-hydroxy-3,3-dimethyl-2,3-dihydrocyclopenta[b]indol-1(4H)- one Acta Crystallographica Section E: Structure Reports Online. 69: o1351-o1352. DOI: 10.1107/S1600536813020527  0.96
2013 Lopchuk JM, Gribble GW, Jasinski JP. Bruceolline D: 3,3-dimethyl-1H,4H-cyclopenta[b]indol-2(3H)-one Acta Crystallographica Section E: Structure Reports Online. 69: o1043. DOI: 10.1107/S1600536813014955  0.96
2013 Lopchuk JM, Montgomery WL, Jasinski JP, Gorjifard S, Gribble GW. Manganese(III)-mediated oxidative radical addition of malonates to 2-cyanoindoles Tetrahedron Letters. 54: 6142-6145. DOI: 10.1016/j.tetlet.2013.09.012  0.96
2013 Badenock JC, Jordan JA, Gribble GW. Synthetic approaches toward the marine alkaloid prenostodione Tetrahedron Letters. 54: 2759-2762. DOI: 10.1016/j.tetlet.2013.02.116  0.96
2013 Gribble GW, Fu L, Lin QX. Attachment at Ring Positions Pyridines. 153-373. DOI: 10.1016/B978-0-12-385235-9.00003-5  0.96
2013 Gribble GW. Food chemistry and chemophobia Food Security. 5: 177-187. DOI: 10.1007/s12571-013-0251-2  0.96
2013 Gribble GW, Roy S. Fluorinated imidazoles and benzimidazoles Fluorine in Heterocyclic Chemistry. 1: 323-367. DOI: 10.1007/978-3-319-04346-3_8  0.96
2013 Pelkey ET, Jiang J, Gribble GW. Synthesis and Diels-Alder reactions of pyrrolo[3,4-b]indoles. A synthesis of 4-acetamidocarbazoles and an approach to the antiostatins Journal of the Indian Chemical Society. 90: 1525-1536.  0.96
2012 Gribble GW. Occurrence of Halogenated Alkaloids Alkaloids: Chemistry and Biology. 71: 1-165. PMID 23189746 DOI: 10.1016/B978-0-12-398282-7.00001-1  0.96
2012 Jordon JA, Badenock JC, Gribble GW, Jasinski JP, Golen JA. 3,3-Dimethyl-1,2,3,4-tetra-hydro-cyclo-penta-[b]indole-1,2-dione (bruceolline E). Acta Crystallographica. Section E, Structure Reports Online. 68: o364-5. PMID 22346990 DOI: 10.1107/S1600536812000517  0.72
2012 Jordon JA, Badenock JC, Gribble GW, Jasinski JP, Golen JA. 3,3-Dimethyl-1,2,3,4-tetrahydrocyclopenta-[b]indole-1,2-dione (bruceolline E) Acta Crystallographica Section E: Structure Reports Online. 68: o364-o365. DOI: 10.1107/S1600536812000517  0.96
2012 Roy S, Gribble GW. Metal-catalyzed amidation Tetrahedron. 68: 9867-9923. DOI: 10.1016/j.tet.2012.08.065  0.96
2012 Wamhoff H, Gribble GW. Wine and Heterocycles Advances in Heterocyclic Chemistry. 106: 185-225. DOI: 10.1016/B978-0-12-396531-8.00003-1  0.96
2011 Honda T, Yoshizawa H, Sundararajan C, David E, Lajoie MJ, Favaloro FG, Janosik T, Su X, Honda Y, Roebuck BD, Gribble GW. Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents Journal of Medicinal Chemistry. 54: 1762-1778. PMID 21361338 DOI: 10.1021/jm101445p  0.96
2011 Sporn MB, Liby KT, Yore MM, Fu L, Lopchuk JM, Gribble GW. New synthetic triterpenoids: Potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress Journal of Natural Products. 74: 537-545. PMID 21309592 DOI: 10.1021/np100826q  0.96
2011 Hughes LM, Lanteri CA, O'Neil MT, Johnson JD, Gribble GW, Trumpower BL. Design of anti-parasitic and anti-fungal hydroxy-naphthoquinones that are less susceptible to drug resistance. Molecular and Biochemical Parasitology. 177: 12-9. PMID 21251932 DOI: 10.1016/j.molbiopara.2011.01.002  0.96
2011 Gribble GW. Recently discovered naturally occurring heterocyclic organohalogen compounds Heterocycles. 84: 157-207. DOI: 10.3987/REV-11-SR(P)5  0.96
2011 Jordan JA, Gribble GW, Badenock JC. A concise total synthesis of bruceolline e Tetrahedron Letters. 52: 6772-6774. DOI: 10.1016/j.tetlet.2011.10.023  0.96
2011 Lopchuk JM, Gribble GW. A convenient 1,3-dipolar cycloaddition approach to pyridylpyrroles Tetrahedron Letters. 52: 4106-4108. DOI: 10.1016/j.tetlet.2011.05.111  0.96
2011 Alford PE, Fu L, Kubert JK, Wang L, Gribble GW. A convenient Fischer indole synthesis of 2,3′-biindoles Tetrahedron Letters. 52: 2642-2644. DOI: 10.1016/j.tetlet.2011.03.049  0.96
2011 Roy S, Gregg BT, Gribble GW, Le VD. Trifluoromethylation of aryl and heteroaryl halides Tetrahedron. 67: 2161-2195. DOI: 10.1016/j.tet.2011.01.002  0.96
2010 Badenock JC, Jordan JA, Pelkey ET, Gribble GW, Jasinski JP. 4-Phenyl-sulfon-yl-2-(p-tolyl-sulfon-yl)-1H,8H-pyrrolo-[2,3-b]indole. Acta Crystallographica. Section E, Structure Reports Online. 66: o2757-8. PMID 21588961 DOI: 10.1107/S1600536810039425  0.72
2010 Rosenfelder N, Ostrowicz P, Fu L, Gribble GW, Tittlemier SA, Frey W, Vetter W. Enantioseparation and absolute configuration of the atropisomers of a naturally produced hexahalogenated 1,1′-dimethyl-2,2′-bipyrrole Journal of Chromatography A. 1217: 2050-2055. PMID 20176363 DOI: 10.1016/j.chroma.2010.01.083  0.96
2010 Gribble GW. Outlook. Fortschritte Der Chemie Organischer Naturstoffe. Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 377-378. PMID 19953390  0.96
2010 Gribble GW. Significance. Fortschritte Der Chemie Organischer Naturstoffe. Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 375-376. PMID 19953389  0.96
2010 Gribble GW. Natural function. Fortschritte Der Chemie Organischer Naturstoffe. Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 369-374. PMID 19953388  0.96
2010 Gribble GW. Biodegradation. Fortschritte Der Chemie Organischer Naturstoffe. Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 367-368. PMID 19953387  0.96
2010 Gribble GW. Biohalogenation. Fortschritte Der Chemie Organischer Naturstoffe. Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 349-365. PMID 19953386  0.96
2010 Gribble GW. Occurrence. Fortschritte Der Chemie Organischer Naturstoffe = Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 9-348. PMID 19953385 DOI: 10.1007/978-3-211-99323-1_3  0.96
2010 Gribble GW. Origins. Fortschritte Der Chemie Organischer Naturstoffe. Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 3-8. PMID 19953384  0.96
2010 Gribble GW. Introduction. Fortschritte Der Chemie Organischer Naturstoffe. Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 91: 1. PMID 19953383  0.96
2010 Hughes LM, Covian R, Gribble GW, Trumpower BL. Probing binding determinants in center P of the cytochrome bc(1) complex using novel hydroxy-naphthoquinones. Biochimica Et Biophysica Acta. 1797: 38-43. PMID 19660431 DOI: 10.1016/j.bbabio.2009.07.010  0.96
2010 Lopchuk JM, Gribble GW. Synthesis of 2-and 3-indolylpyrroles via 1,3-dipolar cycloadditions of münchnones and nitroalkenes Heterocycles. 82: 1617-1631. DOI: 10.3987/COM-10-S(E)125  0.96
2010 Alford PE, Kishbaugh TLS, Gribble GW. Nucleophilic addition of hetaryllithium compounds to 3-Nitro-1- (phenylsulfonyl)indole: Synthesis of tetracyclic thieno[3,2-c]-δ- carbolines Heterocycles. 80: 831-840. DOI: 10.3987/COM-09-S(S)99  0.96
2010 Badenock JC, Jordan JA, Pelkey ET, Gribble GW, Jasinski JP. 4-Phenyl-sulfon-yl-2-(p-tolyl-sulfon-yl)-1H,8H-pyrrolo-[2,3-b]indole Acta Crystallographica Section E: Structure Reports Online. 66: o2757-o2758. DOI: 10.1107/S1600536810039425  0.96
2010 Fu L, Gribble GW. Total synthesis of lycogarubin C utilizing the Kornfeld-Boger ring contraction Tetrahedron Letters. 51: 537-539. DOI: 10.1016/j.tetlet.2009.11.085  0.96
2010 Jasinski JP, Rinderspacher A, Gribble GW. Structures of three new (phenylsulfonyl)indole derivatives Journal of Chemical Crystallography. 40: 40-47. DOI: 10.1007/s10870-009-9603-3  0.96
2010 Gribble GW. Miscellaneous Functional Group Manipulations: Balz-Schiemann Reaction Name Reactions For Functional Group Transformations. 552-563. DOI: 10.1002/9780470176511.ch7  0.96
2010 Qian DC, Alford PE, Kishbaugh TLS, Jones ST, Gribble GW. 1,2-Bis(phenylsulfonyl)-1H-indole as an acceptor of organocuprate nucleophiles Arkivoc. 2010: 66-73.  0.96
2009 Gribble GW, Joule JA. Progress in Heterocyclic Chemistry: Foreword Progress in Heterocyclic Chemistry. 21: xi. DOI: 10.1016/S0959-6380(09)70026-1  0.96
2009 Gribble GW. Miscellaneous Homologation Reactions: Parham Cyclization Name Reactions For Homologations, Part Ii. 749-764. DOI: 10.1002/9780470487044.ch3  0.96
2009 Gribble GW. Rearrangements: Hofmann Rearrangement Name Reactions For Homologations, Part Ii. 164-199. DOI: 10.1002/9780470487044.ch1  0.96
2009 Gribble GW. Organometallics: Organocopper Reagents: Glaser Coupling Name Reactions For Homologations, Part I. 236-257. DOI: 10.1002/9780470487020.ch1  0.96
2008 Liby K, Yore MM, Roebuck BD, Baumgartner KJ, Honda T, Sundararajan C, Yoshizawa H, Gribble GW, Williams CR, Risingsong R, Royce DB, Dinkova-Kostova AT, Stephenson KK, Egner PA, Yates MS, et al. A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin Cancer Research. 68: 6727-6733. PMID 18701497 DOI: 10.1158/0008-5472.CAN-08-1123  0.96
2008 Liby K, Risingsong R, Royce DB, R. Williams C, Yore MM, Honda T, Gribble GW, Lamph WW, Vannini N, Sogno I, Albini A, Sporn MB. Prevention and treatment of experimental estrogen receptor- negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl ester and the rexinoid LG100268 Clinical Cancer Research. 14: 4556-4563. PMID 18628471 DOI: 10.1158/1078-0432.CCR-08-0040  0.96
2008 Liby K, Black CC, Royce DB, Williams CR, Risingsong R, Yore MM, Liu X, Honda T, Gribble GW, Lamph WW, Sporn TA, Dmitrovsky E, Sporn MB. The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis Molecular Cancer Therapeutics. 7: 1251-1257. PMID 18483313 DOI: 10.1158/1535-7163.MCT-08-0023  0.96
2008 Sponholtz WR, Bianco MA, Gribble GW. Isolation and structure determination of the cembranoid eunicin from a new genus of octocoral, Pseudoplexaura. Natural Product Research. 22: 440-7. PMID 18404564 DOI: 10.1080/14786410701591788  0.96
2008 To C, Kulkarni S, Pawson T, Honda T, Gribble GW, Sporn MB, Wrana JL, Di Guglielmo GM. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid-imidazolide alters transforming growth factor β-dependent signaling and cell migration by affecting the cytoskeleton and the polarity complex Journal of Biological Chemistry. 283: 11700-11713. PMID 18283107 DOI: 10.1074/jbc.M704064200  0.96
2008 Dinkova-Kostova AT, Jenkins SN, Wehage SL, Huso DL, Benedict AL, Stephenson KK, Fahey JW, Liu H, Liby KT, Honda T, Gribble GW, Sporn MB, Talalay P. A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice Biochemical and Biophysical Research Communications. 367: 859-865. PMID 18206646 DOI: 10.1016/j.bbrc.2008.01.026  0.96
2008 Sponholtz WR, Bianco MA, Gribble GW. Isolation and structure determination of the cembranoid eunicin from a new genus of octocoral, Pseudoplexaura Natural Product Research. 22: 441-448. DOI: 10.1080/14786410701591788  0.96
2008 Fu L, Gribble GW. A short synthesis of the naturally occurring 2,3',4,4',5,5'- heptachloro- ("Q1") and heptabromo-1'-methyl-l,2'-bipyrroles Organic Preparations and Procedures International. 40: 561-566. DOI: 10.1080/00304940809458121  0.96
2008 Fu L, Gribble GW. One-pot synthesis of pyrrolylamides and pyrrolylimides by tin- and indium-mediated reductive acylation of 2- and 3-nitropyrroles Synthesis. 788-794. DOI: 10.1055/s-2008-1032170  0.96
2008 Fu L, Gribble GW. A simple synthesis of 2,2′-bipyrroles from pyrrole Tetrahedron Letters. 49: 7352-7354. DOI: 10.1016/j.tetlet.2008.10.034  0.96
2008 Androsov DA, Kishbaugh TLS, Gribble GW. Mn(III)-based radical addition reactions of 2-nitroindole with activated CH compounds Tetrahedron Letters. 49: 6621-6623. DOI: 10.1016/j.tetlet.2008.09.020  0.96
2008 Fu L, Gribble GW. Synthesis of 1,2′- and 1,3′-bipyrroles from 2- and 3-nitropyrroles Tetrahedron Letters. 49: 3545-3548. DOI: 10.1016/j.tetlet.2008.04.025  0.96
2008 Roy S, Gribble GW. Efficient reductive acylation of 3-nitroindoles Tetrahedron Letters. 49: 1531-1533. DOI: 10.1016/j.tetlet.2007.12.108  0.96
2008 Gribble GW. The indole alkaloids Second Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds: a Modern Comprehensive Treatise. 4: 69-164. DOI: 10.1016/B978-044453347-0.50159-2  0.96
2008 Gribble GW. Natural products containing a cyclohexane, cyclohexene, or cyclohexadiene subunit Second Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds: a Modern Comprehensive Treatise. 2: 375-445. DOI: 10.1016/B978-044453347-0.50066-5  0.96
2007 Vetter W, Gribble GW. Anthropogenic persistent organic pollutants - Lessons to learn from halogenated natural products Environmental Toxicology and Chemistry. 26: 2249-2252. PMID 17941728 DOI: 10.1897/06-615R.1  0.96
2007 Liby K, Honda T, Williams CR, Risingsong R, Royce DB, Suh N, Dinkova-Kostova AT, Stephenson KK, Talalay P, Sundararajan C, Gribble GW, Sporn MB. Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities Molecular Cancer Therapeutics. 6: 2113-2119. PMID 17620440 DOI: 10.1158/1535-7163.MCT-07-0180  0.96
2007 Kessl JJ, Moskalev NV, Gribble GW, Nasr M, Meshnick SR, Trumpower BL. Parameters determining the relative efficacy of hydroxy-naphthoquinone inhibitors of the cytochrome bc1 complex. Biochimica Et Biophysica Acta. 1767: 319-26. PMID 17383607 DOI: 10.1016/j.bbabio.2007.02.014  0.96
2007 Honda T, Sundararajan C, Yoshizawa H, Su X, Honda Y, Liby KT, Sporn MB, Gribble GW. Novel tricyclic compounds having acetylene groups at C-8a and cyano enones in rings A and C: Highly potent anti-inflammatory and cytoprotective agents Journal of Medicinal Chemistry. 50: 1731-1734. PMID 17367124 DOI: 10.1021/jm070141c  0.96
2007 Liby K, Royce DB, Williams CR, Risingsong R, Yore MM, Honda T, Gribble GW, Dmitrovsky E, Sporn TA, Sporn MB. The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice Cancer Research. 67: 2414-2419. PMID 17363558 DOI: 10.1158/0008-5472.CAN-06-4534  0.96
2007 Fava RA, Elliott S, Raymond L, Mollmark J, Hays E, Honda T, Gribble GW, Sporn MB, Vincenti MP. The synthetic triterpenoid TP-222 inhibits RANKL stimulation of osteoclastogenesis and matrix metalloproteinase-9 expression. The Journal of Rheumatology. 34: 1058-68. PMID 17361985  0.96
2007 Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, Kensler TW. Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes. Molecular Cancer Therapeutics. 6: 154-62. PMID 17237276 DOI: 10.1158/1535-7163.MCT-06-0516  0.96
2007 Kishbaugh TLS, Gribble GW, Jasinski JP. 2-(4-Methoxy-benz-yl)-4-(phenyl-sulfon-yl)-1,2,3,4-tetra-hydro-pyrrolo[3, 4-b]indole Acta Crystallographica Section E: Structure Reports Online. 63: o3411. DOI: 10.1107/S1600536807032436  0.96
2007 Kishbaugh TLS, Gribble GW, Jasinski JP. 2-Benzyl-4-(phenyl-sulfon-yl)-1,2,3,4-tetra-hydro-pyrrolo[3,4-b]indole Acta Crystallographica Section E: Structure Reports Online. 63: o3410. DOI: 10.1107/S1600536807032424  0.96
2007 Kishbaugh TLS, Gribble GW, Jasinski JP. 2-tert-Butyl-4-(phenyl-sulfon-yl)-1,2,3,4-tetra-hydro-pyrrolo[3,4-b]indole Acta Crystallographica Section E: Structure Reports Online. 63: o3409. DOI: 10.1107/S1600536807032412  0.96
2007 Kishbaugh TLS, Gribble GW, Jasinski JP. 2-Isopropyl-4-(phenyl-sulfon-yl)-1,2,3,4-tetra-hydro-pyrrolo[3,4-b]indole Acta Crystallographica Section E: Structure Reports Online. 63: o3408. DOI: 10.1107/S1600536807032400  0.96
2007 Roy S, Gribble GW, Jasinski JP. 2-Nitro-1-(phenylsulfonyl)-1H-indole Acta Crystallographica Section E: Structure Reports Online. 63: o2628-o2629. DOI: 10.1107/S160053680701896X  0.96
2007 Fraser HL, Badenock JC, Gribble GW, Jasinski JP. Azepinyl 2-bromo-1-methyl-1H-indol-3-yl ketone Acta Crystallographica Section E: Structure Reports Online. 63: o2480-o2481. DOI: 10.1107/S1600536807018090  0.96
2007 Badenock JC, Fraser HL, Gribble GW, Jasinski JP. 2-Bromo-N-tertbutyl-N,1-dimethyl-1H-indole-3-carboxamide Acta Crystallographica Section E: Structure Reports Online. 63: o2478-o2479. DOI: 10.1107/S1600536807018089  0.96
2007 Fraser HL, Badenock JC, Gribble GW, Jasinski JP. 1-(2-Bromo-1-methyl-1H-indol-3-ylcarbonyl)piperidine Acta Crystallographica Section E: Structure Reports Online. 63: o2476-o2477. DOI: 10.1107/S1600536807017928  0.96
2007 Badenock JC, Fraser HL, Gribble GW, Jasinski JP. 1-(2-Bromo-1-methyl-1H-indol-3-ylcarbonyl)pyrrolidine Acta Crystallographica Section E: Structure Reports Online. 63: o2474-o2475. DOI: 10.1107/S1600536807017898  0.96
2007 Kishbaugh TLS, Gribble GW, Jasinski JP. 9-(Phenylsulfonyl)-9H-carbazol-2-ol Acta Crystallographica Section E: Structure Reports Online. 63: o2472-o2473. DOI: 10.1107/S160053680701745X  0.96
2007 Kishbaugh TLS, Gribble GW, Jasinski JP. 4-Methoxy-4a-nitro-9-(phenylsulfonyl)-4,4a,9,9a-tetrahydro-1H-carbazol- 2(3H)-one Acta Crystallographica Section E: Structure Reports Online. 63: o2470-o2471. DOI: 10.1107/S1600536807017448  0.96
2007 Roy S, Pelkey ET, Gribble GW, Jasinski JP. 3-Nitro-1-(phenyl-sulfon-yl)-1H-indole Acta Crystallographica Section E: Structure Reports Online. 63: o1829-o1831. DOI: 10.1107/S1600536807011373  0.96
2007 Moskalev NV, Gribble GW, Jasinski JP. 4,6-diphenyl-1-(phenylsulfonyl)-1H-furo[3,4-b]pyrrole Acta Crystallographica Section E: Structure Reports Online. 63: o1279-o1281. DOI: 10.1107/S1600536807005764  0.96
2007 Rinderspacher A, Gribble GW, Butcher RJ, Jasinski JP. 2,3-Diiodo-1-(phenylsulfonyl)-1H-indole Acta Crystallographica Section E: Structure Reports Online. 63: o671-o672. DOI: 10.1107/S1600536807000578  0.96
2007 Rinderspacher A, Gribble GW, Jasinski JP. 2,3-Dibenzyl -(phenylsulfonyl)-1H-indole Acta Crystallographica Section E: Structure Reports Online. 63: o339-o370. DOI: 10.1107/S1600536807000566  0.96
2007 Rinderspacher A, Gribble GW, Jasinski JP. 2,3-Bis(dibromomethyl)-1-(phenylsulfonyl)-1H-indole Acta Crystallographica Section E: Structure Reports Online. 63: o666-o668. DOI: 10.1107/S1600536807000554  0.96
2007 Liu Y, Gribble GW, Jasinski JP. 2,3-Diphenyl-1-(phenylsulfonyl)indole Acta Crystallographica Section E: Structure Reports Online. 63: o738-o740. DOI: 10.1107/S1600536806053694  0.96
2007 Liu Y, Gribble GW, Jasinski JP. 1-(Phenylsulfonyl)-2,3-di-p-tolyl-1H-indole Acta Crystallographica Section E: Structure Reports Online. 63: o735-o737. DOI: 10.1107/S1600536806053682  0.96
2007 Moskalev NV, Gribble GW, Jasinski JP. 4-Ethyl-8-methyl-6-phenyl-1-(phenylsulfonyl)-1H,6H-pyrrolo[3,4-f]indole-5, 7(1H,6H)-dione Acta Crystallographica Section E: Structure Reports Online. 63: o673-o674. DOI: 10.1107/S1600536806053670  0.96
2007 Badenock JC, Fraser HL, Gribble GW, Jasinski JP. 5-methyl-5bβ,6,7,8,9,11 aα-hexahydro-5H-indolizino-[1,2-6]indol- 11(5aαH)-one Acta Crystallographica Section E: Structure Reports Online. 63: o349-o350. DOI: 10.1107/S1600536806053669  0.96
2007 Roy S, Gribble GW. Synthesis of a novel N-nitroalkyl bisindolylmaleimide Synthetic Communications. 37: 1879-1886. DOI: 10.1080/00397910701319205  0.96
2007 Roy S, Gribble GW. Convenient synthesis of bis(3-indolyl)-acetylene via Sonogashira coupling Synthetic Communications. 37: 829-837. DOI: 10.1080/00397910601133631  0.96
2007 Gribble GW. Chapter 3 Indoles Tetrahedron Organic Chemistry Series. 26: 81-188. DOI: 10.1016/S1460-1567(07)80052-3  0.96
2007 Gribble GW. Chapter 2 Pyrroles Tetrahedron Organic Chemistry Series. 26: 37-79. DOI: 10.1016/S1460-1567(07)80051-1  0.96
2007 Li J, Gribble G. Preface to the first edition Tetrahedron Organic Chemistry Series. 26: ix-x. DOI: 10.1016/S1460-1567(07)80048-1  0.96
2007 Li J, Gribble G. Preface to the second edition Tetrahedron Organic Chemistry Series. 26: vii. DOI: 10.1016/S1460-1567(07)80047-X  0.96
2007 Fu L, Gribble GW. Reductive acylation of 2- and 3-nitropyrroles-efficient syntheses of pyrrolylamides and pyrrolylimides Tetrahedron Letters. 48: 9155-9158. DOI: 10.1016/j.tetlet.2007.10.113  0.96
2007 Roy S, Kishbaugh TLS, Jasinski JP, Gribble GW. 1,3-Dipolar cycloaddition of 2- and 3-nitroindoles with azomethine ylides. A new approach to pyrrolo[3,4-b]indoles Tetrahedron Letters. 48: 1313-1316. DOI: 10.1016/j.tetlet.2006.12.125  0.96
2007 Roy S, Gribble GW. Nucleophilic amination of 2-iodo-3-nitro-1-(phenylsulfonyl)indole Tetrahedron Letters. 48: 1003-1005. DOI: 10.1016/j.tetlet.2006.12.004  0.96
2007 Sporn MB, Liby K, Yore MM, Suh N, Albini A, Honda T, Sundararajan C, Gribble GW. Platforms and networks in triterpenoid pharmacology Drug Development Research. 68: 174-182. DOI: 10.1002/ddr.20179  0.96
2007 Gribble GW. Structure and Biosynthesis of Halogenated Alkaloids Modern Alkaloids: Structure, Isolation, Synthesis and Biology. 591-618. DOI: 10.1002/9783527621071.ch19  0.96
2006 Yore MM, Liby KT, Honda T, Gribble GW, Sporn MB. The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta. Molecular Cancer Therapeutics. 5: 3232-9. PMID 17148759 DOI: 10.1158/1535-7163.MCT-06-0444  0.96
2006 Roy S, Eastman A, Gribble GW. Synthesis of bisindolylmaleimides related to GF109203x and their efficient conversion to the bioactive indolocarbazoles. Organic & Biomolecular Chemistry. 4: 3228-34. PMID 17036110 DOI: 10.1039/b607504e  0.96
2006 Roy S, Roy S, Gribble GW. A practical method for the synthesis of indolylaryl- and bisindolylmaleimides. Organic Letters. 8: 4975-7. PMID 17020350 DOI: 10.1021/ol0621203  0.96
2006 Honda T, Liby KT, Su X, Sundararajan C, Honda Y, Suh N, Risingsong R, Williams CR, Royce DB, Sporn MB, Gribble GW. Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A. Bioorganic & Medicinal Chemistry Letters. 16: 6306-9. PMID 16996735 DOI: 10.1016/j.bmcl.2006.09.012  0.96
2006 Liby K, Voong N, Williams CR, Risingsong R, Royce DB, Honda T, Gribble GW, Sporn MB, Letterio JJ. The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4288-93. PMID 16857804 DOI: 10.1158/1078-0432.CCR-06-0215  0.96
2006 Honda T, Yoshizawa H, Sundararajan C, Gribble GW. Synthesis of a novel dicyano abietane analogue: a potential antiinflammatory agent. The Journal of Organic Chemistry. 71: 3314-6. PMID 16599639 DOI: 10.1021/jo060059+  0.96
2006 Yates MS, Kwak MK, Egner PA, Groopman JD, Bodreddigari S, Sutter TR, Baumgartner KJ, Roebuck BD, Liby KT, Yore MM, Honda T, Gribble GW, Sporn MB, Kensler TW. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole. Cancer Research. 66: 2488-94. PMID 16489057 DOI: 10.1158/0008-5472.CAN-05-3823  0.96
2006 Payette JN, Honda T, Yoshizawa H, Favaloro FG, Gribble GW. Study on the base-catalyzed reverse vinylogous aldol reaction of (4abeta,5beta)-4,4a,5,6,7,8-hexahydro-5-hydroxy-1,4a-dimethylnaphthalen-2(3H)-one under Robinson annulation conditions. The Journal of Organic Chemistry. 71: 416-9. PMID 16388674 DOI: 10.1021/jo0520036  0.96
2006 Pelkey ET, Gribble GW. Novel electrophilic ipso acylation - Detosylation reaction of pyrroles Canadian Journal of Chemistry. 84: 1338-1342. DOI: 10.1139/V06-075  0.96
2006 Kishbaugh T, Pelkey ET, Gribble GW, Jasinski JP. 6-Nitro-1-(phenylsulfonyl)-1H-indole Acta Crystallographica Section E: Structure Reports Online. 62: o5760-o5762. DOI: 10.1107/S1600536806048616  0.96
2006 Roy S, Gribble GW. Convenient synthesis of N,N′-bis-protected-3,3′-diiodo-2, 2′-biindoles Synthetic Communications. 36: 3487-3492. DOI: 10.1080/00397910600943253  0.96
2006 Roy S, Haque S, Gribble GW. Synthesis of novel oxazolyl-indoles Synthesis. 3948-3954. DOI: 10.1055/s-2006-950318  0.96
2006 Gribble GW. The synthetic versatility of acyloxyborohydrides Organic Process Research and Development. 10: 1062-1075. DOI: 10.1021/op060107s  0.96
2006 Roy S, Eastman A, Gribble GW. Synthesis of N-alkyl substituted bioactive indolocarbazoles related to Gö6976 Tetrahedron. 62: 7838-7845. DOI: 10.1016/j.tet.2006.05.049  0.96
2006 Roy S, Gribble GW. Convenient synthesis of masked aminoindoles by indium mediated one-pot reductive acylation of 3- and 2-nitroindoles Heterocycles. 70: 51-56.  0.96
2005 Honda T, Honda Y, Yoshizawa H, Gribble GW. AN EFFICIENT SYNTHESIS OF TRICYCLIC COMPOUNDS, (+/-)-(4abeta8abeta10aalpha)-1,2,3,4,4a,6,7,8,8a,9,10,10a-DODECAHYDRO-1,1,4a-TRIMETHYL-2-OXOPHENANTHRENE-8a-CARBOXYLIC ACID, ITS METHYL ESTER, AND (+/-)-(4abeta,8abeta10aalpha)-3,4,4a,6,7,8,8a,9,10,10a-DECAHYDRO-8a-HYDROXYMETHYL-1,1,4a-TRIMETHYLPHENANTHREN-2(1H)-ONE. Organic Preparations and Procedures International. 37: 546-550. PMID 19122785 DOI: 10.1080/00304940509354983  0.96
2005 Samudio I, Konopleva M, Hail N, Shi YX, McQueen T, Hsu T, Evans R, Honda T, Gribble GW, Sporn M, Gilbert HF, Safe S, Andreeff M. 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer. The Journal of Biological Chemistry. 280: 36273-82. PMID 16118208 DOI: 10.1074/jbc.M507518200  0.96
2005 Mohr JT, Gribble GW, Lin SS, Eckenhoff RG, Cantor RS. Anesthetic potency of two novel synthetic polyhydric alkanols longer than the n-alkanol cutoff: evidence for a bilayer-mediated mechanism of anesthesia? Journal of Medicinal Chemistry. 48: 4172-6. PMID 15943489 DOI: 10.1021/jm049459k  0.96
2005 Liby K, Hock T, Yore MM, Suh N, Place AE, Risingsong R, Williams CR, Royce DB, Honda T, Honda Y, Gribble GW, Hill-Kapturczak N, Agarwal A, Sporn MB. The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling. Cancer Research. 65: 4789-98. PMID 15930299 DOI: 10.1158/0008-5472.CAN-04-4539  0.96
2005 Couch RD, Browning RG, Honda T, Gribble GW, Wright DL, Sporn MB, Anderson AC. Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action. Bioorganic & Medicinal Chemistry Letters. 15: 2215-9. PMID 15837296 DOI: 10.1016/j.bmcl.2005.03.031  0.96
2005 Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, Sporn MB, Talalay P. Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress Proceedings of the National Academy of Sciences of the United States of America. 102: 4584-4589. PMID 15767573 DOI: 10.1073/pnas.0500815102  0.96
2005 Gribble GW, Saulnier MG, Pelkey ET, Kishbaugh TLS, Liu Y, Jiang J, Trujillo HA, Keavy DJ, Davis DA, Conway SC, Switzer FL, Roy S, Silva RA, Obaza-Nutaitis JA, Sibi MP, et al. Novel indole chemistry in the synthesis of heterocycles Current Organic Chemistry. 9: 1493-1519. DOI: 10.2174/138527205774370487  0.96
2005 Roy S, Eastman A, Gribble GW. Synthesis of 7-keto-Gö6976 (ICP-103) Synthetic Communications. 35: 595-601. DOI: 10.1081/SCC-200049803  0.96
2005 Roy S, Gribble GW. A convenient synthesis of 2-nitroindoles Tetrahedron Letters. 46: 1325-1328. DOI: 10.1016/j.tetlet.2004.12.112  0.96
2005 Gribble GW. Barton-zard reaction Name Reactions in Heterocyclic Chemistry. 70-78. DOI: 10.1002/0471704156.ch2  0.96
2004 Honda T, Janosik T, Honda Y, Han J, Liby KT, Williams CR, Couch RD, Anderson AC, Sporn MB, Gribble GW. Design, synthesis, and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets. Journal of Medicinal Chemistry. 47: 4923-32. PMID 15369396 DOI: 10.1021/jm049727e  0.96
2004 Chauhan D, Li G, Podar K, Hideshima T, Shringarpure R, Catley L, Mitsiades C, Munshi N, Tai YT, Suh N, Gribble GW, Honda T, Schlossman R, Richardson P, Sporn MB, et al. The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance. Blood. 103: 3158-66. PMID 15070698 DOI: 10.1182/blood-2003-08-2873  0.96
2004 Pedersen IM, Zapata JM, Samuel T, Scott FL, Salvesen GS, Honda T, Gribble GW, Suh N, Sporn MB, Kipps TJ, Reed JC. Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells. Blood. 104: 932. PMID 14739219 DOI: 10.1182/blood-2003-11-3774  0.96
2004 Gribble GW. Natural organohalogens: A new frontier for medicinal agents? Journal of Chemical Education. 81: 1441-1449.  0.96
2004 Janosik T, Lipson AC, Gribble GW. An efficient synthesis of 2,3-dicyanoindole Organic Preparations and Procedures International. 36: 289-292.  0.96
2003 Honda T, Favaloro FG, Janosik T, Honda Y, Suh N, Sporn MB, Gribble GW. Efficient synthesis of (-)- and (+)-tricyclic compounds with enone functionalities in rings A and C. A novel class of orally active anti-inflammatory and cancer chemopreventive agents. Organic & Biomolecular Chemistry. 1: 4384-91. PMID 14685310 DOI: 10.1039/b307491a  0.96
2003 Ikeda T, Sporn M, Honda T, Gribble GW, Kufe D. The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance. Cancer Research. 63: 5551-8. PMID 14500394  0.96
2003 Place AE, Suh N, Williams CR, Risingsong R, Honda T, Honda Y, Gribble GW, Leesnitzer LM, Stimmel JB, Willson TM, Rosen E, Sporn MB. The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2798-806. PMID 12855660  0.96
2003 Honda Y, Honda T, Roy S, Gribble GW. Revision and confirmation of the regiochemistry of isoxazoles derived from methyl oleanonate and lanost-8-en-3-one. Synthesis of a new lanostane triterpenoid with a cyano-enone functionality in ring A. The Journal of Organic Chemistry. 68: 4991-3. PMID 12790619 DOI: 10.1021/jo034056y  0.96
2003 Gribble GW. The diversity of naturally produced organohalogens. Chemosphere. 52: 289-97. PMID 12738253 DOI: 10.1016/S0045-6535(03)00207-8  0.96
2003 Suh N, Roberts AB, Birkey Reffey S, Miyazono K, Itoh S, ten Dijke P, Heiss EH, Place AE, Risingsong R, Williams CR, Honda T, Gribble GW, Sporn MB. Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling. Cancer Research. 63: 1371-6. PMID 12649201  0.96
2003 Gribble GW. Chapter 3 Naturally occurring halogenated pyrroles and Indoles Progress in Heterocyclic Chemistry. 15: 58-74. DOI: 10.1016/S0959-6380(03)80005-3  0.96
2003 Gribble GW. Novel chemistry of indole in the synthesis of heterocycles Pure and Applied Chemistry. 75: 1417-1432.  0.96
2002 Wu J, Vetter W, Gribble GW, Schneekloth JS, Blank DH, Görls H. Structure and synthesis of the natural heptachloro-1'-methyl-1,2'-bipyrrole (Q1). Angewandte Chemie (International Ed. in English). 41: 1740-3. PMID 19750701 DOI: 10.1002/1521-3773(20020517)41:10<1740::AID-ANIE1740>3.0.CO;2-7  0.96
2002 Eastman A, Kohn EA, Brown MK, Rathman J, Livingstone M, Blank DH, Gribble GW. A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: similarities and differences to the cell cycle checkpoint abrogator UCN-01. Molecular Cancer Therapeutics. 1: 1067-78. PMID 12481430  0.96
2002 Kim KB, Lotan R, Yue P, Sporn MB, Suh N, Gribble GW, Honda T, Wu GS, Hong WK, Sun SY. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells. Molecular Cancer Therapeutics. 1: 177-84. PMID 12467212  0.96
2002 Favaloro FG, Honda T, Honda Y, Gribble GW, Suh N, Risingsong R, Sporn MB. Design and synthesis of tricyclic compounds with enone functionalities in rings A and C: a novel class of highly active inhibitors of nitric oxide production in mouse macrophages. Journal of Medicinal Chemistry. 45: 4801-5. PMID 12383005 DOI: 10.1021/jm025565f  0.96
2002 Bore L, Honda T, Gribble GW. Partial synthesis of 23-hydroxyursolic acid isolated from medicinal plants of the Rubiaceae family. Natural Product Letters. 16: 273-6. PMID 12168764 DOI: 10.1080/10575630290020622  0.96
2002 Liu Y, Gribble GW. Syntheses of polybrominated indoles from the red alga Laurencia brongniartii and the brittle star Ophiocoma erinaceus. Journal of Natural Products. 65: 748-9. PMID 12027758 DOI: 10.1021/np010610s  0.96
2002 Honda T, Honda Y, Favaloro FG, Gribble GW, Suh N, Place AE, Rendi MH, Sporn MB. A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production. Bioorganic & Medicinal Chemistry Letters. 12: 1027-30. PMID 11909709 DOI: 10.1016/S0960-894X(02)00105-1  0.96
2002 Bore L, Honda T, Gribble GW, Lork E, Jasinski JP. The anti-inflammatory triterpenoid methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate methanol solvate hydrate. Acta Crystallographica. Section C, Crystal Structure Communications. 58: o199-200. PMID 11870328 DOI: 10.1107/S010827010102176X  0.96
2002 Gribble GW, Jiang J, Liu Y. An efficient synthesis of 4-(phenylsulfonyl)-4H-furo[3,4-b]indoles. The Journal of Organic Chemistry. 67: 1001-3. PMID 11856051 DOI: 10.1021/jo010938q  0.96
2002 Tittlemier SA, Blank DH, Gribble GW, Norstrom RJ. Structure elucidation of four possible biogenic organohalogens using isotope exchange mass spectrometry. Chemosphere. 46: 511-7. PMID 11838429 DOI: 10.1016/S0045-6535(01)00174-6  0.96
2002 Jiang J, Gribble GW. A direct lithiation route to 2-acyl-1-(phenylsulfonyl)indoles Synthetic Communications. 32: 2035-2040. DOI: 10.1081/SCC-120004854  0.96
2002 Kishbaugh TLS, Gribble GW. Synthesis of N-substituted pyrrolo[3,4-b]indoles from 2,3-dimethylindole Synthetic Communications. 32: 2003-2008. DOI: 10.1081/SCC-120004850  0.96
2002 Blank DH, Gribble GW, Schneekloth JS, Jasinski JP. A novel class of naturally occurring halogenated pyrroles, 1,1′-dimethyl-3,3′,4,4′,5,5′-hexabromo-2, 2′-bipyrrole, 5,5′-dichloro-1,1′-dimethyl-3,3′ ,4,4′-tetrabromo-2,2′-bipyrrole, and 1,1′-dimethyl-3,3′ ,4,4′,5,5′-hexachloro-2,2′-bipyrrole Journal of Chemical Crystallography. 32: 541-546. DOI: 10.1023/A:1021117431367  0.96
2002 Liu Y, Gribble GW. Selective lithiation of 2,3-dibromo-1-methylindole. A synthesis of 2,3-disubstituted indoles Tetrahedron Letters. 43: 7135-7137. DOI: 10.1016/S0040-4039(02)01710-0  0.96
2002 Jiang J, Gribble GW. A new synthesis of 2-nitroindoles Tetrahedron Letters. 43: 4115-4117. DOI: 10.1016/S0040-4039(02)00696-2  0.96
2002 Finlay HJ, Honda T, Gribble GW. Synthesis of novel [3,2-b]indole fused oleanolic acids as potential inhibitors of cell proliferation Arkivoc. 2002: 38-46.  0.96
2002 Jiang J, Gribble GW. An efficient synthesis of 1,3-dimethyl-4-(phenylsulfonyl)-4H-furo[3,4-b]indole Organic Preparations and Procedures International. 34: 533-535.  0.96
2002 Moskalev NV, Gribble GW. Synthesis and Diels-Alder reactions of the furo[3,4-b]pyrrole ring system. A new indole ring synthesis Tetrahedron Letters. 43: 197-201.  0.96
2001 Fraser HL, Gribble GW. A synthesis of 6,11-disubstituted benzo[b]carbazoles Canadian Journal of Chemistry. 79: 1515-1521. DOI: 10.1139/cjc-79-11-1515  0.96
2001 Kishbaugh TLS, Gribble GW. Diels-Alder reactions of 2- and 3-nitroindoles. A simple hydroxycarbazole synthesis Tetrahedron Letters. 42: 4783-4785. DOI: 10.1016/S0040-4039(01)00854-1  0.96
2001 Liu Y, Gribble GW. Generation and reactions of 2,3-dilithio-N-methylindole. Synthesis of 2,3-disubstituted indoles Tetrahedron Letters. 42: 2949-2951. DOI: 10.1016/S0040-4039(01)00332-X  0.96
2001 Gribble GW, Liu Y. Ruthenium catalyzed oxidation of haloindoles to isatins Organic Preparations and Procedures International. 33: 615-619.  0.96
2001 Gribble GW, Fraser HL, Badenock JC. A novel radical cyclization of 2-bromoindoles. Synthesis of hexahydropyrrolo[3,4-b]indoles Chemical Communications. 805-806.  0.96
2000 Honda T, Rounds BV, Bore L, Finlay HJ, Favaloro FG, Suh N, Wang Y, Sporn MB, Gribble GW. Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages. Journal of Medicinal Chemistry. 43: 4233-46. PMID 11063620 DOI: 10.1021/jm0002230  0.96
2000 Wang Y, Porter WW, Suh N, Honda T, Gribble GW, Leesnitzer LM, Plunket KD, Mangelsdorf DJ, Blanchard SG, Willson TM, Sporn MB. A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma. Molecular Endocrinology (Baltimore, Md.). 14: 1550-6. PMID 11043571 DOI: 10.1210/mend.14.10.0545  0.96
2000 Bore L, Honda T, Gribble GW. Synthesis of beta-Boswellic acid analogues with a carboxyl group at C-17 isolated from the bark of Schefflera octophylla. The Journal of Organic Chemistry. 65: 6278-82. PMID 10987979 DOI: 10.1021/jo0008688  0.96
2000 Ito Y, Pandey P, Place A, Sporn MB, Gribble GW, Honda T, Kharbanda S, Kufe D. The novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 11: 261-7. PMID 10845427  0.96
2000 Simon WM, Trujillo HA, Pelkey ET, Gribble GW, Jasinski JP. The fused heterocycle 2-benzyl-3-methyl-1-phenyl-4-phenylsulfonyl-2H,4H-pyrrolo Acta Crystallographica. Section C, Crystal Structure Communications. 56: 461-2. PMID 10815210  0.72
2000 Honda T, Gribble GW, Suh N, Finlay HJ, Rounds BV, Bore L, Favaloro FG, Wang Y, Sporn MB. Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages. Journal of Medicinal Chemistry. 43: 1866-77. PMID 10794703 DOI: 10.1021/jm000008j  0.96
2000 Trujillo HA, Simon WM, Pelkey ET, Gribble GW, Jasinski JP. A novel class of fused heterocycles, benzo Acta Crystallographica. Section C, Crystal Structure Communications. 56: 386-8. PMID 10777962  0.72
2000 Gribble GW. Recent developments in indole ring synthesis - Methodology and applications Journal of the Chemical Society, Perkin Transactions 1. 1045-1075. DOI: 10.1039/a909834h  0.96
2000 Sponholtz WR, Trujillo HA, Gribble GW. Tandem 1,3-dipolar cycloaddition of mesoionic 2,4-diphenyl-1,3- oxathiolium-5-olate with cycloocta-1,5-diene. A new synthesis of the tetracyclo[6.2.0.04,10.05,9]decane ring system Tetrahedron Letters. 41: 1687-1690. DOI: 10.1016/S0040-4039(00)00042-3  0.96
2000 Gribble GW, Pelkey ET, Simon WM, Trujillo HA. Regioselective 1,3-dipolar cycloaddition reactions of unsymmetrical munchnones (1,3-oxazolium-5-olates) with 2- and 3-nitroindoles. A new synthesis of pyrrolo[3,4-b]indoles Tetrahedron. 56: 10133-10140. DOI: 10.1016/S0040-4020(00)00858-9  0.96
2000 Liu Y, Gribble GW. Bis-Suzuki reactions of 2,3-dihaloindoles. A convenient synthesis of 2,3-diarylindoles Tetrahedron Letters. 41: 8717-8721.  0.96
1999 Honda T, Rounds BV, Bore L, Favaloro FG, Gribble GW, Suh N, Wang Y, Spor MB. Novel synthetic oleanane triterpenoids: a series of highly active inhibitors of nitric oxide production in mouse macrophages. Bioorganic & Medicinal Chemistry Letters. 9: 3429-34. PMID 10617085  0.36
1999 Suh N, Wang Y, Honda T, Gribble GW, Dmitrovsky E, Hickey WF, Maue RA, Place AE, Porter DM, Spinella MJ, Williams CR, Wu G, Dannenberg AJ, Flanders KC, Letterio JJ, et al. A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. Cancer Research. 59: 336-41. PMID 9927043  0.96
1998 Honda T, Rounds BV, Gribble GW, Suh N, Wang Y, Sporn MB. Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages. Bioorganic & Medicinal Chemistry Letters. 8: 2711-4. PMID 9873608  0.36
1998 Suh N, Honda T, Finlay HJ, Barchowsky A, Williams C, Benoit NE, Xie QW, Nathan C, Gribble GW, Sporn MB. Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages. Cancer Research. 58: 717-23. PMID 9485026  0.96
1986 Obaza-Nutaitis JA, Gribble GW. Synthesis of 13-oxoellipticine. Journal of Natural Products. 49: 449-51. PMID 3760885  0.48
1986 Von Jagow G, Gribble GW, Trumpower BL. Mucidin and strobilurin A are identical and inhibit electron transfer in the cytochrome bc1 complex of the mitochondrial respiratory chain at the same site as myxothiazol. Biochemistry. 25: 775-80. PMID 3008811  0.96
Show low-probability matches.